GREMLIN Database
Chlam_OMP6 - Chlamydia cysteine-rich outer membrane protein 6
PFAM: PF03504 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 91 (78)
Sequences: 779 (681)
Seq/√Len: 77.1
META: 0.935

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
55_F58_A5.5201.00
49_L53_V3.6331.00
30_I34_N3.3271.00
28_Y34_N3.3151.00
62_A70_L3.0841.00
78_A81_E2.3861.00
70_L87_V2.3481.00
45_V85_I2.0551.00
32_V83_A1.9451.00
63_T72_W1.8251.00
23_T26_S1.7831.00
12_V16_K1.7151.00
30_I36_G1.7041.00
57_S88_T1.6171.00
39_D76_T1.6031.00
58_A62_A1.6021.00
31_T84_T1.5790.99
16_K47_D1.5190.99
72_W85_I1.2860.98
20_A25_G1.2600.97
49_L70_L1.2600.97
12_V40_A1.2490.97
41_T81_E1.1760.96
65_T70_L1.1260.95
43_V75_G1.1160.95
32_V36_G1.0970.94
29_T47_D1.0970.94
53_V89_V1.0910.94
62_A72_W1.0840.94
19_P22_A1.0350.92
22_A33_T1.0190.92
15_T31_T1.0020.91
47_D70_L0.9870.90
32_V45_V0.9670.90
21_E25_G0.9660.89
40_A43_V0.9610.89
83_A87_V0.9540.89
28_Y32_V0.9250.87
40_A79_A0.9080.86
70_L74_I0.9060.86
64_V68_G0.9010.86
64_V67_G0.8950.86
72_W87_V0.8800.85
60_P64_V0.8680.84
59_T86_T0.8570.83
53_V87_V0.8520.83
26_S51_A0.8380.82
21_E26_S0.7990.78
25_G75_G0.7970.78
28_Y53_V0.7910.78
68_G71_T0.7900.78
14_I52_G0.7880.77
34_N37_P0.7820.77
64_V72_W0.7760.76
40_A52_G0.7730.76
48_T54_T0.7680.76
39_D78_A0.7680.76
48_T69_T0.7620.75
20_A23_T0.7510.74
28_Y44_V0.7460.73
43_V85_I0.7410.73
37_P69_T0.7310.72
29_T86_T0.7300.72
36_G40_A0.7200.71
47_D69_T0.7150.70
50_P54_T0.7070.69
63_T69_T0.6980.68
29_T84_T0.6950.68
38_S79_A0.6930.68
60_P72_W0.6810.67
66_A69_T0.6680.65
65_T69_T0.6630.65
16_K25_G0.6610.64
44_V81_E0.6550.64
53_V79_A0.6540.63
31_T58_A0.6520.63
44_V71_T0.6510.63
63_T70_L0.6460.62
45_V75_G0.6450.62
64_V70_L0.6450.62
44_V83_A0.6420.62
55_F72_W0.6390.62
27_T56_V0.6350.61
45_V67_G0.6320.61
22_A68_G0.6320.61
56_V61_A0.6300.61
44_V56_V0.6200.59
34_N77_L0.6080.58
16_K19_P0.6020.57
49_L89_V0.6010.57
63_T84_T0.5970.56
22_A26_S0.5950.56
24_V85_I0.5910.56
20_A43_V0.5860.55
42_N84_T0.5820.55
54_T65_T0.5790.54
85_I88_T0.5770.54
20_A24_V0.5740.54
61_A82_S0.5720.53
33_T37_P0.5680.53
26_S76_T0.5610.52
50_P53_V0.5580.52
74_I85_I0.5490.50
59_T88_T0.5490.50
13_T23_T0.5460.50
37_P49_L0.5450.50
36_G41_T0.5430.50
13_T52_G0.5420.50
18_A23_T0.5310.48
42_N61_A0.5290.48
27_T57_S0.5270.48
35_T53_V0.5220.47
33_T82_S0.5210.47
12_V17_T0.5200.47
38_S51_A0.5160.46
18_A24_V0.5090.45
21_E24_V0.5000.44
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3iduA 1 0.7912 95.4 0.775 Contact Map
2l0dA 1 0.7582 93.3 0.796 Contact Map
2kutA 1 0.7802 90.2 0.813 Contact Map
4phzA 3 0.956 89.1 0.817 Contact Map
4ziqA 2 0.989 81.7 0.835 Contact Map
4hsqA 1 0.8681 81.2 0.836 Contact Map
2iaaC 1 0.9121 77.3 0.842 Contact Map
4tshB 1 1 77.1 0.842 Contact Map
1cuoA 1 0.8462 75.4 0.844 Contact Map
1yewA 3 0.956 75 0.845 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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