Serinc - PFAM28P - GREMLIN Contacts

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Serinc - Serine incorporator (Serinc)

PFAM:	PF03348	Sequences: CCCGSAACSLCCSCCPSCKNSTSTRLAYALILLLGSIVAWIMLSPGVEEKLKKFIPFCEGLQGGGDCYGYLAVYRVCFALALFFFLLALLMIGVKSSKDPRAAIQNGFWFFKILLLLGLIVGAFFIPNGFFITVWNYIGLIGAFLFILIQLILLVDFAHSWNESWVEKAEEGNSKLWYAALLGSTLLMYALSIAGTVLLYVFYAPSGCSLNKFFISINLILCIIVSVVSIHPKVQEAQPRSGLLQSSVVSLYCTYLTWSALSSEPDEECNPLLLSSIGTRTTTVILGLIITFLCVLYSTIRASSNSQVNKLRASRAAVEEGSLPASALDDEDDEEDGDDEDGGRVEDDERDGVQYSYSFFHFIFFLASLYVAMLLTNWYSPDSADLKVTIGSGWAAVWVKIVSSWVCLLLYLWTLVAPLVLPDRD	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_10
Length:	425 (423)
Sequences:	941 (539)
Seq/√Len:	26.2
META:	0.142

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
200_Y	216_S	6.568	1.00
213_F	217_I	6.469	1.00
161_W	165_W	5.754	1.00
194_A	198_L	5.648	1.00
58_C	67_C	4.564	1.00
197_V	201_V	4.446	1.00
208_C	269_C	4.064	1.00
228_V	412_L	3.645	1.00
217_I	221_L	3.607	1.00
264_E	397_V	3.220	1.00
165_W	180_A	3.136	1.00
189_Y	226_S	3.062	1.00
394_W	397_V	2.975	1.00
225_V	412_L	2.927	1.00
218_N	404_S	2.923	1.00
190_A	194_A	2.895	1.00
88_A	362_F	2.838	1.00
78_F	131_F	2.596	0.99
193_I	197_V	2.556	0.99
211_N	264_E	2.556	0.99
192_S	250_S	2.530	0.99
210_L	213_F	2.506	0.99
134_V	138_I	2.498	0.99
222_C	250_S	2.490	0.99
264_E	394_W	2.466	0.99
195_G	199_L	2.429	0.99
216_S	220_I	2.420	0.99
142_G	369_L	2.401	0.99
191_L	251_L	2.322	0.98
214_F	397_V	2.314	0.98
4_G	12_C	2.280	0.98
81_A	365_F	2.224	0.98
216_S	219_L	2.197	0.97
417_A	424_R	2.189	0.97
155_V	297_Y	2.122	0.97
421_L	424_R	2.088	0.97
1_C	8_C	2.018	0.96
398_W	405_W	1.975	0.95
229_S	246_S	1.948	0.95
195_G	254_T	1.908	0.94
414_T	421_L	1.888	0.94
181_L	185_T	1.884	0.94
203_Y	211_N	1.876	0.94
4_G	8_C	1.857	0.93
257_T	401_I	1.847	0.93
95_K	99_D	1.846	0.93
3_C	17_S	1.835	0.93
10_L	16_P	1.806	0.92
34_L	410_L	1.783	0.92
5_S	17_S	1.773	0.92
265_P	400_K	1.771	0.92
355_Y	361_H	1.762	0.91
198_L	201_V	1.760	0.91
373_M	378_W	1.756	0.91
109_W	112_K	1.754	0.91
85_F	365_F	1.747	0.91
241_S	245_Q	1.745	0.91
105_Q	394_W	1.739	0.91
105_Q	162_N	1.711	0.90
164_S	168_K	1.699	0.90
188_M	251_L	1.698	0.90
81_A	85_F	1.691	0.90
265_P	394_W	1.674	0.89
256_L	376_T	1.668	0.89
413_W	417_A	1.668	0.89
299_T	304_S	1.660	0.89
1_C	4_G	1.654	0.89
413_W	418_P	1.649	0.88
18_C	23_S	1.647	0.88
180_A	184_S	1.644	0.88
225_V	408_L	1.623	0.88
218_N	257_T	1.619	0.87
2_C	9_S	1.615	0.87
50_K	53_K	1.611	0.87
159_H	240_R	1.604	0.87
188_M	247_S	1.600	0.87
308_V	312_R	1.598	0.87
31_I	162_N	1.591	0.86
34_L	287_G	1.567	0.86
196_T	254_T	1.521	0.84
253_C	408_L	1.506	0.83
21_S	24_T	1.495	0.83
78_F	123_A	1.489	0.83
242_G	245_Q	1.477	0.82
369_L	374_L	1.469	0.82
11_C	14_C	1.464	0.81
102_A	352_G	1.455	0.81
7_A	11_C	1.445	0.81
40_W	364_F	1.445	0.81
300_I	303_S	1.441	0.80
220_I	420_V	1.440	0.80
415_L	418_P	1.405	0.79
413_W	424_R	1.404	0.79
162_N	166_V	1.403	0.79
318_V	324_P	1.402	0.78
203_Y	270_N	1.398	0.78
44_S	47_V	1.390	0.78
192_S	254_T	1.380	0.77
370_Y	378_W	1.370	0.77
3_C	6_A	1.358	0.76
200_Y	219_L	1.356	0.76
211_N	261_L	1.349	0.76
1_C	16_P	1.324	0.74
12_C	15_C	1.318	0.74
211_N	357_Y	1.317	0.74
319_E	323_L	1.313	0.74
185_T	226_S	1.311	0.74
120_I	285_I	1.309	0.73
335_E	340_E	1.307	0.73
263_S	400_K	1.305	0.73
136_N	393_G	1.295	0.73
89_L	92_I	1.294	0.73
38_V	115_L	1.291	0.72
320_E	326_S	1.290	0.72
85_F	88_A	1.289	0.72
118_G	122_G	1.286	0.72
1_C	5_S	1.285	0.72
8_C	11_C	1.271	0.71
309_N	312_R	1.265	0.71
161_W	177_W	1.264	0.71
97_S	349_E	1.255	0.70
2_C	14_C	1.248	0.70
321_G	324_P	1.246	0.70
123_A	126_I	1.244	0.70
321_G	327_A	1.240	0.69
218_N	239_P	1.237	0.69
159_H	414_T	1.236	0.69
161_W	188_M	1.234	0.69
31_I	113_I	1.227	0.68
220_I	224_I	1.225	0.68
369_L	372_A	1.224	0.68
193_I	220_I	1.221	0.68
83_F	87_L	1.215	0.68
115_L	201_V	1.213	0.68
1_C	12_C	1.211	0.67
148_L	402_V	1.208	0.67
261_L	308_V	1.206	0.67
6_A	12_C	1.188	0.66
237_A	419_L	1.176	0.65
117_L	223_I	1.170	0.65
414_T	424_R	1.165	0.64
2_C	11_C	1.163	0.64
135_W	139_G	1.161	0.64
35_G	80_L	1.153	0.63
298_S	304_S	1.151	0.63
72_A	124_F	1.148	0.63
27_A	31_I	1.148	0.63
69_G	414_T	1.143	0.63
86_L	115_L	1.143	0.63
143_A	376_T	1.139	0.63
79_A	119_L	1.135	0.62
150_Q	244_L	1.133	0.62
359_F	373_M	1.132	0.62
256_L	407_C	1.132	0.62
223_I	348_D	1.125	0.62
25_R	101_R	1.122	0.61
82_L	123_A	1.120	0.61
139_G	372_A	1.116	0.61
23_S	27_A	1.113	0.61
173_N	230_I	1.111	0.61
376_T	403_S	1.108	0.60
6_A	9_S	1.103	0.60
9_S	15_C	1.103	0.60
384_A	387_K	1.102	0.60
42_M	72_A	1.101	0.60
4_G	17_S	1.099	0.60
168_K	199_L	1.098	0.60
49_E	52_K	1.092	0.59
165_W	178_Y	1.092	0.59
90_L	186_L	1.087	0.59
256_L	259_S	1.086	0.59
182_L	341_D	1.085	0.59
127_P	287_G	1.085	0.59
5_S	8_C	1.079	0.58
250_S	296_L	1.077	0.58
10_L	17_S	1.075	0.58
77_C	135_W	1.073	0.58
84_F	257_T	1.073	0.58
215_I	229_S	1.072	0.58
265_P	397_V	1.070	0.58
30_L	34_L	1.055	0.57
228_V	231_H	1.053	0.56
39_A	76_V	1.050	0.56
6_A	10_L	1.050	0.56
124_F	361_H	1.048	0.56
3_C	7_A	1.046	0.56
144_F	359_F	1.044	0.56
294_C	374_L	1.041	0.56
225_V	253_C	1.040	0.55
5_S	10_L	1.038	0.55
41_I	228_V	1.034	0.55
91_M	105_Q	1.033	0.55
264_E	365_F	1.030	0.55
199_L	211_N	1.026	0.54
310_K	322_S	1.022	0.54
7_A	13_S	1.014	0.54
224_I	416_V	1.014	0.54
94_V	101_R	1.014	0.54
316_A	320_E	1.012	0.53
335_E	338_D	1.010	0.53
1_C	14_C	1.009	0.53
161_W	180_A	1.006	0.53
199_L	261_L	1.001	0.53
145_L	363_I	0.998	0.52
159_H	247_S	0.993	0.52
317_A	321_G	0.993	0.52
242_G	260_A	0.992	0.52
55_I	71_L	0.991	0.52
356_S	420_V	0.984	0.51
257_T	404_S	0.983	0.51
8_C	28_Y	0.979	0.51
196_T	219_L	0.978	0.51
123_A	139_G	0.976	0.51
336_D	339_D	0.975	0.51
14_C	18_C	0.974	0.51
67_C	75_R	0.969	0.50
241_S	263_S	0.969	0.50
198_L	202_F	0.965	0.50
301_R	304_S	0.964	0.50
1_C	6_A	0.962	0.50
391_G	396_A	0.956	0.49
113_I	287_G	0.955	0.49
403_S	407_C	0.954	0.49
152_I	311_L	0.954	0.49
360_F	373_M	0.933	0.48
11_C	17_S	0.932	0.47
422_P	425_D	0.930	0.47
228_V	234_V	0.930	0.47
1_C	10_L	0.929	0.47
136_N	258_W	0.929	0.47
34_L	53_K	0.927	0.47
233_K	362_F	0.926	0.47
122_G	187_L	0.926	0.47
172_G	206_S	0.924	0.47
293_L	375_L	0.923	0.47
9_S	12_C	0.923	0.47
162_N	393_G	0.922	0.47
166_V	193_I	0.920	0.47
312_R	363_I	0.916	0.46
227_V	231_H	0.916	0.46
266_D	401_I	0.913	0.46
244_L	258_W	0.912	0.46
211_N	394_W	0.912	0.46
327_A	333_D	0.909	0.46
159_H	245_Q	0.909	0.46
186_L	190_A	0.908	0.46
2_C	6_A	0.908	0.46
114_L	370_Y	0.905	0.45
147_I	263_S	0.904	0.45
85_F	89_L	0.902	0.45
87_L	414_T	0.900	0.45
193_I	216_S	0.891	0.44
7_A	12_C	0.889	0.44
319_E	322_S	0.885	0.44
32_L	40_W	0.884	0.44
288_L	302_A	0.883	0.44
417_A	421_L	0.882	0.44
83_F	142_G	0.881	0.44
31_I	116_L	0.880	0.44
252_Y	398_W	0.879	0.44
200_Y	215_I	0.877	0.43
87_L	344_R	0.873	0.43
308_V	313_A	0.872	0.43
416_V	420_V	0.872	0.43
143_A	395_A	0.871	0.43
310_K	313_A	0.870	0.43
29_A	155_V	0.869	0.43
271_P	403_S	0.868	0.43
389_T	397_V	0.867	0.43
137_Y	246_S	0.865	0.43
219_L	224_I	0.864	0.42
48_E	51_L	0.864	0.42
156_D	297_Y	0.863	0.42
299_T	303_S	0.862	0.42
157_F	298_S	0.861	0.42
91_M	94_V	0.859	0.42
375_L	397_V	0.849	0.41
370_Y	373_M	0.849	0.41
54_F	400_K	0.848	0.41
212_K	216_S	0.844	0.41
51_L	121_V	0.843	0.41
214_F	401_I	0.840	0.41
32_L	364_F	0.839	0.41
121_V	126_I	0.839	0.41
161_W	184_S	0.839	0.41
381_P	393_G	0.838	0.41
413_W	421_L	0.837	0.40
88_A	92_I	0.835	0.40
281_T	285_I	0.834	0.40
109_W	355_Y	0.831	0.40
313_A	321_G	0.826	0.40
187_L	409_L	0.826	0.40
307_Q	310_K	0.823	0.39
155_V	229_S	0.822	0.39
120_I	190_A	0.821	0.39
360_F	367_A	0.818	0.39
97_S	348_D	0.817	0.39
215_I	251_L	0.816	0.39
201_V	209_S	0.810	0.39
219_L	269_C	0.809	0.39
122_G	125_F	0.809	0.39
82_L	119_L	0.808	0.38
291_T	390_I	0.807	0.38
6_A	14_C	0.804	0.38
4_G	15_C	0.804	0.38
151_L	242_G	0.802	0.38
94_V	353_V	0.797	0.38
224_I	268_E	0.794	0.37
246_S	256_L	0.793	0.37
288_L	299_T	0.793	0.37
4_G	9_S	0.790	0.37
184_S	203_Y	0.790	0.37
6_A	16_P	0.788	0.37
318_V	328_L	0.787	0.37
238_Q	425_D	0.786	0.37
255_Y	259_S	0.783	0.37
115_L	289_I	0.782	0.37
85_F	194_A	0.780	0.36
361_H	367_A	0.780	0.36
19_K	22_T	0.779	0.36
318_V	321_G	0.777	0.36
162_N	169_A	0.777	0.36
338_D	341_D	0.775	0.36
225_V	261_L	0.775	0.36
236_E	239_P	0.774	0.36
285_I	289_I	0.774	0.36
21_S	25_R	0.773	0.36
106_N	407_C	0.772	0.36
172_G	295_V	0.772	0.36
114_L	117_L	0.771	0.36
32_L	43_L	0.769	0.36
298_S	370_Y	0.764	0.35
32_L	156_D	0.763	0.35
92_I	149_I	0.763	0.35
157_F	161_W	0.762	0.35
185_T	419_L	0.760	0.35
144_F	399_V	0.760	0.35
75_R	270_N	0.758	0.35
295_V	364_F	0.755	0.35
179_A	183_G	0.751	0.35
308_V	368_S	0.741	0.34
184_S	188_M	0.739	0.34
92_I	95_K	0.736	0.34
211_N	215_I	0.736	0.34
74_Y	150_Q	0.735	0.33
265_P	399_V	0.734	0.33
84_F	130_F	0.728	0.33
81_A	393_G	0.728	0.33
412_L	416_V	0.728	0.33
397_V	404_S	0.725	0.33
334_E	337_G	0.724	0.33
85_F	90_L	0.724	0.33
154_L	297_Y	0.723	0.33
319_E	327_A	0.723	0.33
189_Y	246_S	0.722	0.33
121_V	125_F	0.722	0.33
59_E	199_L	0.722	0.33
195_G	198_L	0.719	0.32
256_L	295_V	0.718	0.32
230_I	243_L	0.717	0.32
242_G	252_Y	0.714	0.32
270_N	303_S	0.714	0.32
39_A	246_S	0.714	0.32
77_C	373_M	0.714	0.32
115_L	148_L	0.712	0.32
76_V	384_A	0.711	0.32
332_D	340_E	0.710	0.32
266_D	270_N	0.709	0.32
70_Y	407_C	0.709	0.32
261_L	305_N	0.707	0.32
58_C	75_R	0.707	0.32
236_E	242_G	0.706	0.32
45_P	49_E	0.706	0.32
185_T	425_D	0.706	0.32
235_Q	417_A	0.704	0.31
146_F	189_Y	0.704	0.31
229_S	242_G	0.703	0.31
166_V	178_Y	0.700	0.31
29_A	33_L	0.699	0.31
37_I	152_I	0.697	0.31
24_T	102_A	0.694	0.31
33_L	86_L	0.694	0.31
151_L	245_Q	0.693	0.31
153_L	376_T	0.691	0.31
318_V	323_L	0.691	0.31
119_L	357_Y	0.691	0.31
140_L	218_N	0.690	0.31
138_I	191_L	0.690	0.31
260_A	265_P	0.690	0.31
399_V	405_W	0.689	0.30
384_A	410_L	0.688	0.30
2_C	13_S	0.687	0.30
159_H	185_T	0.686	0.30
106_N	245_Q	0.685	0.30
77_C	371_V	0.684	0.30
213_F	220_I	0.684	0.30
63_G	79_A	0.683	0.30
254_T	362_F	0.683	0.30
92_I	385_D	0.681	0.30
165_W	184_S	0.681	0.30
187_L	190_A	0.679	0.30
382_D	421_L	0.677	0.30
137_Y	393_G	0.675	0.30
143_A	213_F	0.675	0.30
99_D	365_F	0.674	0.30
14_C	17_S	0.674	0.30
82_L	223_I	0.673	0.29
220_I	227_V	0.672	0.29
320_E	323_L	0.671	0.29
36_S	123_A	0.671	0.29
230_I	279_T	0.670	0.29
151_L	159_H	0.667	0.29
150_Q	378_W	0.665	0.29
244_L	302_A	0.665	0.29
162_N	291_T	0.663	0.29
191_L	198_L	0.662	0.29
123_A	127_P	0.659	0.29
146_F	374_L	0.659	0.29
153_L	288_L	0.659	0.29
414_T	417_A	0.657	0.29
246_S	419_L	0.656	0.28
151_L	361_H	0.656	0.28
277_I	414_T	0.656	0.28
88_A	383_S	0.656	0.28
214_F	261_L	0.655	0.28
317_A	326_S	0.655	0.28
414_T	422_P	0.654	0.28
416_V	424_R	0.653	0.28
406_V	412_L	0.653	0.28
180_A	203_Y	0.653	0.28
154_L	365_F	0.652	0.28
25_R	245_Q	0.651	0.28
176_L	180_A	0.650	0.28
2_C	10_L	0.650	0.28
148_L	152_I	0.650	0.28
139_G	144_F	0.649	0.28
300_I	305_N	0.649	0.28
308_V	311_L	0.648	0.28
290_I	410_L	0.647	0.28
11_C	309_N	0.647	0.28
259_S	376_T	0.645	0.28
49_E	190_A	0.645	0.28
85_F	256_L	0.645	0.28
51_L	401_I	0.645	0.28
157_F	263_S	0.643	0.28
195_G	251_L	0.643	0.28
152_I	214_F	0.643	0.28
8_C	13_S	0.639	0.27
83_F	225_V	0.639	0.27
203_Y	244_L	0.638	0.27
111_F	273_L	0.636	0.27
189_Y	231_H	0.636	0.27
67_C	112_K	0.635	0.27
281_T	409_L	0.635	0.27
359_F	378_W	0.635	0.27
31_I	143_A	0.632	0.27
259_S	400_K	0.632	0.27
353_V	356_S	0.628	0.27
106_N	242_G	0.628	0.27
156_D	177_W	0.628	0.27
127_P	398_W	0.627	0.27
227_V	351_D	0.626	0.27
151_L	218_N	0.625	0.27
46_G	54_F	0.624	0.27
317_A	327_A	0.621	0.26
306_S	310_K	0.618	0.26
84_F	238_Q	0.618	0.26
47_V	76_V	0.618	0.26
156_D	376_T	0.617	0.26
319_E	324_P	0.614	0.26
247_S	367_A	0.612	0.26
153_L	403_S	0.612	0.26
124_F	405_W	0.612	0.26
357_Y	361_H	0.611	0.26
334_E	342_G	0.611	0.26
334_E	341_D	0.609	0.26
402_V	409_L	0.609	0.26
98_K	358_S	0.608	0.26
299_T	397_V	0.607	0.26
143_A	228_V	0.606	0.26
380_S	383_S	0.605	0.25
277_I	341_D	0.605	0.25
211_N	256_L	0.605	0.25
139_G	369_L	0.603	0.25
40_W	44_S	0.603	0.25
77_C	393_G	0.602	0.25
322_S	327_A	0.601	0.25
221_L	348_D	0.601	0.25
24_T	216_S	0.600	0.25
150_Q	165_W	0.600	0.25
181_L	235_Q	0.600	0.25
94_V	283_T	0.597	0.25
6_A	17_S	0.597	0.25
125_F	128_N	0.596	0.25
241_S	403_S	0.596	0.25
39_A	108_F	0.595	0.25
74_Y	108_F	0.595	0.25
332_D	335_E	0.594	0.25
124_F	241_S	0.594	0.25
225_V	270_N	0.593	0.25
357_Y	400_K	0.590	0.25
23_S	113_I	0.589	0.25
38_V	87_L	0.589	0.25
43_L	377_N	0.585	0.24
349_E	353_V	0.585	0.24
78_F	135_W	0.585	0.24
177_W	287_G	0.585	0.24
138_I	385_D	0.585	0.24
136_N	143_A	0.584	0.24
171_E	230_I	0.582	0.24
299_T	393_G	0.582	0.24
4_G	7_A	0.582	0.24
18_C	27_A	0.580	0.24
189_Y	374_L	0.580	0.24
210_L	214_F	0.579	0.24
337_G	340_E	0.578	0.24
303_S	308_V	0.578	0.24
208_C	211_N	0.577	0.24
126_I	284_V	0.576	0.24
418_P	424_R	0.574	0.24
373_M	398_W	0.574	0.24
261_L	277_I	0.572	0.24
245_Q	357_Y	0.571	0.24
126_I	270_N	0.571	0.24
264_E	357_Y	0.571	0.24
46_G	196_T	0.570	0.24
162_N	368_S	0.568	0.23
38_V	42_M	0.568	0.23
81_A	230_I	0.567	0.23
78_F	82_L	0.567	0.23
125_F	132_I	0.563	0.23
58_C	69_G	0.562	0.23
315_R	318_V	0.560	0.23
52_K	409_L	0.558	0.23
11_C	22_T	0.557	0.23
11_C	345_V	0.556	0.23
46_G	396_A	0.556	0.23
138_I	171_E	0.556	0.23
102_A	247_S	0.555	0.23
81_A	368_S	0.554	0.23
26_L	419_L	0.552	0.23
154_L	397_V	0.552	0.23
126_I	153_L	0.552	0.23
138_I	266_D	0.550	0.22
210_L	217_I	0.550	0.22
254_T	302_A	0.549	0.22
143_A	369_L	0.549	0.22
128_N	207_G	0.549	0.22
193_I	337_G	0.549	0.22
247_S	252_Y	0.548	0.22
153_L	159_H	0.547	0.22
365_F	369_L	0.546	0.22
162_N	173_N	0.544	0.22
235_Q	240_R	0.544	0.22
123_A	131_F	0.542	0.22
25_R	91_M	0.542	0.22
267_E	367_A	0.540	0.22
246_S	384_A	0.540	0.22
291_T	391_G	0.540	0.22
366_L	421_L	0.540	0.22
79_A	234_V	0.540	0.22
207_G	211_N	0.539	0.22
91_M	99_D	0.538	0.22
45_P	379_Y	0.537	0.22
393_G	396_A	0.537	0.22
137_Y	140_L	0.537	0.22
155_V	158_A	0.536	0.22
212_K	218_N	0.536	0.22
369_L	379_Y	0.536	0.22
216_S	223_I	0.536	0.22
152_I	201_V	0.536	0.22
314_S	319_E	0.536	0.22
290_I	351_D	0.535	0.22
83_F	369_L	0.533	0.22
65_G	113_I	0.532	0.22
157_F	170_E	0.532	0.22
70_Y	87_L	0.531	0.22
30_L	123_A	0.531	0.22
135_W	407_C	0.530	0.21
96_S	197_V	0.530	0.21
46_G	51_L	0.529	0.21
159_H	235_Q	0.529	0.21
364_F	390_I	0.529	0.21
232_P	245_Q	0.528	0.21
98_K	120_I	0.527	0.21
291_T	302_A	0.527	0.21
84_F	87_L	0.527	0.21
138_I	168_K	0.527	0.21
211_N	364_F	0.526	0.21
74_Y	116_L	0.525	0.21
203_Y	272_L	0.525	0.21
139_G	363_I	0.525	0.21
303_S	363_I	0.524	0.21
63_G	255_Y	0.524	0.21
373_M	396_A	0.524	0.21
197_V	364_F	0.523	0.21
17_S	103_A	0.523	0.21
220_I	289_I	0.523	0.21
264_E	393_G	0.521	0.21
151_L	260_A	0.521	0.21
48_E	52_K	0.519	0.21
303_S	310_K	0.519	0.21
25_R	32_L	0.518	0.21
222_C	408_L	0.517	0.21
262_S	380_S	0.517	0.21
86_L	227_V	0.517	0.21
305_N	359_F	0.516	0.21
141_I	203_Y	0.515	0.21
398_W	401_I	0.514	0.21
154_L	251_L	0.513	0.21
2_C	254_T	0.513	0.21
219_L	417_A	0.512	0.21
220_I	343_G	0.512	0.21
405_W	424_R	0.512	0.21
150_Q	373_M	0.511	0.21
77_C	368_S	0.510	0.20
11_C	15_C	0.510	0.20
90_L	219_L	0.509	0.20
263_S	370_Y	0.506	0.20
203_Y	258_W	0.506	0.20
188_M	211_N	0.505	0.20
393_G	408_L	0.504	0.20
278_G	323_L	0.504	0.20
180_A	290_I	0.503	0.20
29_A	40_W	0.503	0.20
405_W	415_L	0.503	0.20
26_L	226_S	0.503	0.20
313_A	325_A	0.502	0.20
106_N	185_T	0.502	0.20
27_A	48_E	0.502	0.20
59_E	425_D	0.502	0.20
152_I	344_R	0.501	0.20
28_Y	361_H	0.500	0.20
149_I	377_N	0.500	0.20

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4pypA	1	0.6329	19.5	0.975	Contact Map
3dl8E	1	0.1482	9.3	0.979	Contact Map
4bgnA	3	0.4565	7.3	0.98	Contact Map
1yewC	1	0.1624	6.2	0.98	Contact Map
3j1rA	5	0.0612	4.8	0.981	Contact Map
4ymkA	1	0.1859	4.2	0.982	Contact Map
4zw9A	1	0.1718	4.2	0.982	Contact Map
5a63B	1	0.0635	4.1	0.982	Contact Map
1dl0A	1	0.08	2.8	0.983	Contact Map
2mf3A	1	0.0424	2.6	0.984	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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