GerA - PFAM28P - GREMLIN Contacts

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GerA - Bacillus/Clostridium GerA spore germination protein

PFAM:	PF03323	Sequences: QYLKEIFGNSSDLVIREFKIGGIKAALVYIDGLVDKELINEFILKPLMELSEEELEEDEELLENLLPVSEVKEVDDLDEIIDAILSGDTVLLIDGEDEALIIDTRGWPKRSVEEPETEKVVRGPREGFTETLRTNTALIRRRIRDPNLKIESLTVGRRSKTDVAIAYIEGIANPELVEEVKKRLKKIDIDGILDSGYIEELIEDNPYSPFPQVLYTERPDVVAAALLEGRVAILVDGSPFVLIVPATFFEFFQSPEDYYQRPIIGSFLRLLRFLAFFISLLLPALYVALTTFHPEMIPTELLLSIAASREGVPFPAFVEALLMEITFELLREAGIRLPKPIGQAISIVGALVIGQAAVQAGLVSPIMVIVVALTAIASFAIPSYELSIAIRLLRFPLLILAALFGLYGIILGLILLLIHLASLRSFGVPYLSPLAPFNLKDLKDTLIRAPLWKMKKRPSY	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_10
Length:	460 (457)
Sequences:	7032 (5528)
Seq/√Len:	258.6
META:	0.514

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
151_E	181_K	6.095	1.00
222_V	232_A	5.277	1.00
400_L	412_G	4.476	1.00
157_R	188_D	4.184	1.00
89_T	104_T	4.147	1.00
355_Q	359_Q	4.097	1.00
172_A	177_V	3.307	1.00
150_I	166_A	3.167	1.00
203_E	261_R	3.116	1.00
76_D	79_E	2.839	1.00
165_I	181_K	2.805	1.00
320_A	367_M	2.755	1.00
150_I	164_A	2.749	1.00
74_V	101_I	2.711	1.00
73_E	98_E	2.689	1.00
191_G	227_L	2.679	1.00
287_V	398_L	2.658	1.00
147_N	170_G	2.652	1.00
90_V	101_I	2.640	1.00
281_L	413_L	2.630	1.00
149_K	169_E	2.599	1.00
213_V	244_V	2.572	1.00
155_V	184_L	2.561	1.00
80_I	90_V	2.541	1.00
397_L	412_G	2.514	1.00
153_L	185_K	2.497	1.00
168_I	171_I	2.475	1.00
126_E	142_R	2.475	1.00
84_I	90_V	2.375	1.00
139_I	166_A	2.342	1.00
133_R	136_T	2.301	1.00
74_V	79_E	2.301	1.00
234_L	241_V	2.234	1.00
139_I	234_L	2.230	1.00
401_A	409_I	2.173	1.00
397_L	416_L	2.163	1.00
145_D	158_R	2.144	1.00
252_F	276_F	2.131	1.00
13_L	30_I	2.128	1.00
216_T	222_V	2.105	1.00
178_E	182_K	2.072	1.00
88_D	105_R	2.062	1.00
194_D	238_S	2.025	1.00
179_E	182_K	2.024	1.00
169_E	174_P	2.015	1.00
158_R	170_G	2.012	1.00
83_A	101_I	1.996	1.00
317_F	402_A	1.954	1.00
180_V	231_V	1.948	1.00
17_E	24_K	1.945	1.00
132_L	164_A	1.931	1.00
174_P	178_E	1.911	1.00
195_S	235_V	1.903	1.00
177_V	231_V	1.898	1.00
37_E	41_E	1.863	1.00
82_D	160_K	1.856	1.00
83_A	88_D	1.848	1.00
284_A	401_A	1.847	1.00
91_L	102_I	1.843	1.00
182_K	186_K	1.843	1.00
324_E	394_R	1.838	1.00
147_N	169_E	1.836	1.00
266_S	270_L	1.817	1.00
10_S	149_K	1.817	1.00
179_E	183_R	1.808	1.00
8_G	149_K	1.807	1.00
320_A	398_L	1.798	1.00
233_I	244_V	1.782	1.00
19_K	24_K	1.769	1.00
421_A	431_L	1.769	1.00
155_V	163_V	1.768	1.00
225_A	243_I	1.767	1.00
153_L	181_K	1.765	1.00
180_V	244_V	1.738	1.00
92_L	99_A	1.733	1.00
189_I	201_L	1.723	1.00
246_A	251_F	1.721	1.00
75_D	98_E	1.718	1.00
13_L	28_V	1.690	1.00
9_N	151_E	1.682	1.00
115_P	127_G	1.681	1.00
15_I	26_A	1.660	1.00
124_P	259_Y	1.657	1.00
154_T	162_D	1.653	1.00
163_V	235_V	1.645	1.00
437_F	442_L	1.643	1.00
152_S	162_D	1.635	1.00
183_R	204_D	1.624	1.00
143_I	223_A	1.611	1.00
159_S	191_G	1.603	1.00
152_S	164_A	1.602	1.00
35_D	106_G	1.594	1.00
41_E	45_K	1.579	1.00
31_D	133_R	1.574	1.00
168_I	226_L	1.571	1.00
275_A	329_L	1.529	1.00
114_E	127_G	1.525	1.00
284_A	397_L	1.516	1.00
4_K	15_I	1.511	1.00
88_D	103_D	1.506	1.00
15_I	28_V	1.496	1.00
407_Y	411_L	1.496	1.00
315_P	318_V	1.493	1.00
90_V	99_A	1.485	1.00
153_L	165_I	1.468	1.00
172_A	231_V	1.468	1.00
34_V	39_I	1.453	1.00
258_Y	444_D	1.445	1.00
86_S	144_R	1.439	1.00
70_E	103_D	1.437	1.00
154_T	160_K	1.433	1.00
114_E	125_R	1.427	1.00
396_P	400_L	1.427	1.00
139_I	148_L	1.414	1.00
419_H	423_L	1.402	1.00
107_W	141_R	1.395	1.00
109_K	134_T	1.383	1.00
136_T	150_I	1.383	1.00
275_A	380_A	1.367	1.00
80_I	99_A	1.365	1.00
287_V	320_A	1.361	1.00
283_P	374_T	1.361	1.00
88_D	101_I	1.359	1.00
267_F	392_L	1.356	1.00
420_L	431_L	1.354	1.00
59_E	63_E	1.353	1.00
82_D	154_T	1.351	1.00
328_E	395_F	1.349	1.00
393_L	416_L	1.345	1.00
72_K	83_A	1.343	1.00
230_R	250_E	1.337	1.00
9_N	169_E	1.325	1.00
276_F	390_I	1.324	1.00
143_I	227_L	1.323	1.00
158_R	171_I	1.314	1.00
33_L	137_A	1.308	1.00
132_L	234_L	1.305	1.00
208_S	212_Q	1.294	1.00
32_G	137_A	1.286	1.00
180_V	233_I	1.283	1.00
166_A	234_L	1.273	1.00
74_V	80_I	1.268	1.00
116_E	125_R	1.267	1.00
68_V	102_I	1.265	1.00
213_V	242_L	1.258	1.00
20_I	25_A	1.255	1.00
176_L	231_V	1.246	1.00
62_L	73_E	1.241	1.00
178_E	181_K	1.236	1.00
208_S	419_H	1.230	1.00
327_F	375_A	1.229	1.00
113_E	116_E	1.225	1.00
247_T	428_V	1.225	1.00
210_F	430_Y	1.213	1.00
16_R	71_V	1.208	1.00
438_N	441_D	1.201	1.00
251_F	386_L	1.188	1.00
324_E	395_F	1.182	1.00
25_A	93_I	1.181	1.00
26_A	92_L	1.175	1.00
433_P	436_P	1.172	1.00
210_F	393_L	1.172	1.00
317_F	399_I	1.171	1.00
7_F	85_L	1.170	1.00
112_V	126_E	1.163	1.00
39_I	89_T	1.158	1.00
326_T	352_V	1.155	1.00
119_K	339_K	1.152	1.00
187_I	198_I	1.150	1.00
324_E	398_L	1.150	1.00
109_K	131_T	1.149	1.00
126_E	141_R	1.149	1.00
128_F	222_V	1.148	1.00
222_V	241_V	1.148	1.00
317_F	398_L	1.145	1.00
17_E	26_A	1.140	1.00
139_I	222_V	1.136	1.00
247_T	250_E	1.135	1.00
288_A	409_I	1.134	1.00
314_F	318_V	1.129	1.00
434_L	445_T	1.126	1.00
181_K	185_K	1.121	1.00
193_L	197_Y	1.114	1.00
194_D	259_Y	1.111	1.00
165_I	231_V	1.110	1.00
270_L	274_L	1.099	1.00
147_N	158_R	1.096	1.00
107_W	131_T	1.095	1.00
232_A	243_I	1.092	1.00
122_R	199_E	1.091	1.00
214_L	243_I	1.087	1.00
449_A	454_M	1.084	1.00
231_V	244_V	1.083	1.00
200_E	448_R	1.082	1.00
39_I	104_T	1.077	1.00
12_D	140_R	1.076	1.00
43_I	102_I	1.074	1.00
249_F	434_L	1.067	1.00
214_L	246_A	1.055	1.00
175_E	178_E	1.052	1.00
285_L	409_I	1.051	1.00
290_T	316_A	1.045	1.00
136_T	166_A	1.044	1.00
281_L	397_L	1.037	1.00
129_T	135_N	1.036	1.00
159_S	227_L	1.035	1.00
280_L	393_L	1.035	1.00
7_F	81_I	1.024	1.00
108_P	134_T	1.024	1.00
173_N	428_V	1.020	1.00
9_N	149_K	1.016	1.00
243_I	250_E	1.015	1.00
316_A	367_M	1.012	1.00
79_E	82_D	1.011	1.00
182_K	185_K	1.010	1.00
27_L	91_L	1.010	1.00
32_G	133_R	1.005	1.00
442_L	445_T	0.999	1.00
165_I	180_V	0.997	1.00
443_K	449_A	0.992	1.00
166_A	226_L	0.991	1.00
232_A	241_V	0.986	1.00
171_I	457_R	0.984	1.00
190_D	457_R	0.982	1.00
59_E	73_E	0.975	1.00
210_F	420_L	0.971	1.00
321_L	398_L	0.969	1.00
279_S	390_I	0.968	1.00
3_L	28_V	0.968	1.00
171_I	190_D	0.967	1.00
143_I	168_I	0.966	1.00
34_V	104_T	0.966	1.00
144_R	236_D	0.964	1.00
6_I	81_I	0.962	1.00
170_G	174_P	0.961	1.00
10_S	13_L	0.959	1.00
176_L	426_F	0.959	1.00
72_K	79_E	0.958	1.00
137_A	141_R	0.954	1.00
248_F	431_L	0.953	1.00
11_S	151_E	0.953	1.00
28_V	92_L	0.950	1.00
32_G	136_T	0.948	1.00
252_F	273_F	0.947	1.00
144_R	162_D	0.947	1.00
125_R	240_F	0.946	1.00
158_R	190_D	0.943	1.00
277_F	281_L	0.939	1.00
214_L	221_V	0.938	1.00
399_I	402_A	0.934	1.00
308_S	366_I	0.934	1.00
120_V	256_E	0.933	1.00
30_I	33_L	0.932	1.00
440_K	456_K	0.927	1.00
80_I	92_L	0.923	1.00
281_L	409_I	0.919	1.00
279_S	381_I	0.919	1.00
224_A	228_E	0.917	1.00
225_A	250_E	0.916	1.00
109_K	129_T	0.913	1.00
117_T	240_F	0.913	1.00
111_S	129_T	0.912	1.00
377_A	380_A	0.911	1.00
77_L	80_I	0.910	1.00
166_A	241_V	0.908	1.00
35_D	38_L	0.907	1.00
214_L	250_E	0.900	1.00
221_V	255_P	0.899	1.00
448_R	451_L	0.887	1.00
14_V	31_D	0.886	1.00
200_E	451_L	0.885	1.00
189_I	192_I	0.885	1.00
128_F	139_I	0.880	1.00
209_P	419_H	0.880	1.00
222_V	243_I	0.879	1.00
308_S	365_P	0.877	1.00
317_F	321_L	0.875	1.00
77_L	92_L	0.875	1.00
129_T	134_T	0.874	1.00
24_K	94_D	0.872	1.00
120_V	255_P	0.870	1.00
275_A	377_A	0.868	1.00
126_E	138_L	0.868	1.00
19_K	64_N	0.867	1.00
187_I	201_L	0.865	1.00
131_T	134_T	0.862	1.00
274_L	325_I	0.861	1.00
11_S	152_S	0.861	1.00
44_L	48_M	0.857	1.00
120_V	254_S	0.857	1.00
62_L	100_L	0.855	1.00
395_F	399_I	0.853	0.99
384_Y	388_I	0.852	0.99
324_E	371_V	0.851	0.99
291_T	316_A	0.851	0.99
210_F	416_L	0.850	0.99
27_L	89_T	0.848	0.99
126_E	237_G	0.848	0.99
203_E	212_Q	0.844	0.99
389_A	393_L	0.844	0.99
139_I	223_A	0.839	0.99
396_P	415_L	0.834	0.99
214_L	225_A	0.832	0.99
440_K	443_K	0.832	0.99
248_F	386_L	0.831	0.99
196_G	200_E	0.829	0.99
287_V	402_A	0.828	0.99
346_S	351_L	0.828	0.99
177_V	180_V	0.826	0.99
212_Q	261_R	0.825	0.99
270_L	446_L	0.824	0.99
417_L	421_A	0.824	0.99
134_T	137_A	0.823	0.99
209_P	263_I	0.823	0.99
328_E	331_R	0.819	0.99
184_L	233_I	0.818	0.99
215_Y	242_L	0.818	0.99
25_A	91_L	0.818	0.99
18_F	27_L	0.816	0.99
28_V	84_I	0.816	0.99
359_Q	365_P	0.813	0.99
225_A	230_R	0.812	0.99
305_I	366_I	0.811	0.99
280_L	390_I	0.807	0.99
145_D	160_K	0.805	0.99
329_L	380_A	0.805	0.99
215_Y	240_F	0.805	0.99
121_V	256_E	0.804	0.99
206_P	452_W	0.804	0.99
158_R	168_I	0.803	0.99
73_E	100_L	0.803	0.99
180_V	426_F	0.802	0.99
176_L	180_V	0.801	0.99
174_P	177_V	0.799	0.99
267_F	328_E	0.798	0.99
293_H	405_G	0.796	0.99
59_E	62_L	0.794	0.99
253_Q	258_Y	0.793	0.99
166_A	232_A	0.792	0.99
6_I	146_P	0.787	0.99
159_S	193_L	0.787	0.99
14_V	29_Y	0.786	0.99
409_I	412_G	0.784	0.99
183_R	202_I	0.784	0.99
249_F	445_T	0.782	0.99
60_E	64_N	0.782	0.99
244_V	426_F	0.781	0.99
411_L	415_L	0.781	0.99
122_R	215_Y	0.781	0.99
439_L	443_K	0.781	0.99
133_R	162_D	0.778	0.99
142_R	237_G	0.775	0.99
112_V	138_L	0.775	0.99
269_R	444_D	0.774	0.99
62_L	65_L	0.774	0.99
324_E	331_R	0.774	0.99
438_N	459_S	0.774	0.99
400_L	403_L	0.774	0.99
38_L	104_T	0.774	0.99
86_S	162_D	0.773	0.99
432_S	438_N	0.771	0.99
19_K	63_E	0.769	0.99
443_K	454_M	0.767	0.99
162_D	236_D	0.764	0.99
260_Q	388_I	0.763	0.99
109_K	141_R	0.763	0.99
348_V	375_A	0.761	0.99
108_P	137_A	0.760	0.99
414_I	417_L	0.760	0.99
161_T	235_V	0.759	0.99
7_F	10_S	0.758	0.99
202_I	213_V	0.757	0.99
282_L	373_L	0.757	0.99
3_L	15_I	0.757	0.99
158_R	457_R	0.754	0.99
5_E	8_G	0.753	0.99
266_S	447_I	0.753	0.99
203_E	206_P	0.753	0.99
205_N	212_Q	0.751	0.99
213_V	426_F	0.749	0.99
145_D	168_I	0.747	0.99
79_E	83_A	0.746	0.99
142_R	223_A	0.742	0.99
432_S	441_D	0.741	0.99
74_V	99_A	0.740	0.99
248_F	276_F	0.740	0.99
278_I	282_L	0.739	0.99
211_P	251_F	0.737	0.99
212_Q	423_L	0.736	0.98
172_A	176_L	0.735	0.98
187_I	190_D	0.734	0.98
304_S	361_G	0.733	0.98
267_F	325_I	0.729	0.98
214_L	251_F	0.728	0.98
136_T	164_A	0.726	0.98
46_P	67_P	0.725	0.98
199_E	215_Y	0.724	0.98
45_K	49_E	0.722	0.98
247_T	251_F	0.718	0.98
397_L	401_A	0.718	0.98
434_L	446_L	0.717	0.98
321_L	325_I	0.716	0.98
246_A	249_F	0.715	0.98
17_E	63_E	0.714	0.98
228_E	258_Y	0.714	0.98
197_Y	451_L	0.714	0.98
198_I	202_I	0.712	0.98
449_A	453_K	0.711	0.98
283_P	398_L	0.710	0.98
115_P	217_E	0.708	0.98
78_D	82_D	0.708	0.98
18_F	44_L	0.707	0.98
358_V	365_P	0.706	0.98
396_P	416_L	0.706	0.98
194_D	197_Y	0.705	0.98
31_D	36_K	0.704	0.98
281_L	285_L	0.700	0.98
356_A	360_A	0.699	0.98
249_F	273_F	0.699	0.98
197_Y	224_A	0.696	0.98
113_E	127_G	0.696	0.98
122_R	195_S	0.695	0.98
153_L	184_L	0.692	0.98
14_V	70_E	0.692	0.98
72_K	88_D	0.691	0.98
82_D	86_S	0.691	0.98
398_L	402_A	0.691	0.98
278_I	373_L	0.690	0.98
75_D	97_D	0.688	0.98
19_K	22_G	0.688	0.98
448_R	454_M	0.687	0.98
323_M	363_V	0.687	0.98
110_R	130_E	0.687	0.98
334_G	342_G	0.686	0.98
355_Q	372_A	0.685	0.98
192_I	197_Y	0.684	0.98
148_L	166_A	0.684	0.98
358_V	369_I	0.683	0.98
157_R	190_D	0.680	0.97
176_L	428_V	0.680	0.97
71_V	102_I	0.677	0.97
195_S	242_L	0.677	0.97
131_T	162_D	0.675	0.97
450_P	453_K	0.674	0.97
443_K	456_K	0.673	0.97
260_Q	385_E	0.670	0.97
132_L	152_S	0.669	0.97
324_E	391_R	0.668	0.97
169_E	172_A	0.667	0.97
23_I	94_D	0.667	0.97
31_D	70_E	0.664	0.97
18_F	25_A	0.663	0.97
74_V	90_V	0.662	0.97
391_R	395_F	0.661	0.97
224_A	253_Q	0.661	0.97
93_I	96_E	0.659	0.97
142_R	161_T	0.659	0.97
23_I	96_E	0.659	0.97
131_T	141_R	0.659	0.97
253_Q	444_D	0.658	0.97
3_L	13_L	0.658	0.97
193_L	227_L	0.658	0.97
270_L	447_I	0.656	0.97
399_I	403_L	0.655	0.97
262_P	266_S	0.654	0.97
75_D	79_E	0.653	0.97
38_L	42_F	0.652	0.97
151_E	169_E	0.652	0.97
81_I	146_P	0.652	0.97
34_V	89_T	0.651	0.97
148_L	226_L	0.651	0.97
155_V	187_I	0.650	0.97
309_R	312_V	0.649	0.97
125_R	217_E	0.649	0.97
314_F	362_L	0.646	0.97
406_L	409_I	0.645	0.97
293_H	406_L	0.644	0.97
201_L	451_L	0.644	0.97
246_A	250_E	0.644	0.97
167_Y	172_A	0.643	0.96
334_G	340_P	0.642	0.96
279_S	378_S	0.640	0.96
47_L	91_L	0.639	0.96
118_E	221_V	0.638	0.96
86_S	105_R	0.638	0.96
4_K	17_E	0.634	0.96
155_V	198_I	0.633	0.96
138_L	141_R	0.632	0.96
351_L	372_A	0.632	0.96
207_Y	453_K	0.630	0.96
151_E	165_I	0.628	0.96
198_I	235_V	0.628	0.96
262_P	450_P	0.627	0.96
444_D	454_M	0.624	0.96
128_F	241_V	0.623	0.96
3_L	92_L	0.623	0.96
282_L	370_V	0.622	0.96
143_I	226_L	0.622	0.96
192_I	198_I	0.621	0.96
339_K	345_I	0.621	0.96
251_F	383_S	0.619	0.96
292_F	403_L	0.617	0.96
105_R	133_R	0.617	0.96
179_E	204_D	0.617	0.96
337_L	379_F	0.616	0.96
384_Y	387_S	0.615	0.96
18_F	48_M	0.615	0.96
253_Q	269_R	0.614	0.95
49_E	52_E	0.612	0.95
179_E	186_K	0.610	0.95
178_E	185_K	0.609	0.95
122_R	194_D	0.608	0.95
289_L	406_L	0.607	0.95
201_L	452_W	0.605	0.95
381_I	390_I	0.604	0.95
283_P	324_E	0.602	0.95
248_F	420_L	0.602	0.95
173_N	177_V	0.601	0.95
127_G	217_E	0.600	0.95
378_S	387_S	0.599	0.95
334_G	344_A	0.599	0.95
119_K	340_P	0.599	0.95
31_D	136_T	0.598	0.95
132_L	236_D	0.597	0.95
163_V	198_I	0.596	0.95
142_R	193_L	0.595	0.95
322_L	326_T	0.595	0.95
59_E	98_E	0.595	0.95
328_E	391_R	0.595	0.95
206_P	261_R	0.594	0.95
27_L	44_L	0.593	0.95
117_T	127_G	0.593	0.95
165_I	233_I	0.591	0.94
131_T	236_D	0.591	0.94
258_Y	269_R	0.590	0.94
163_V	195_S	0.590	0.94
265_G	268_L	0.590	0.94
255_P	259_Y	0.587	0.94
287_V	291_T	0.586	0.94
122_R	196_G	0.586	0.94
206_P	209_P	0.586	0.94
186_K	424_R	0.585	0.94
285_L	289_L	0.585	0.94
143_I	159_S	0.584	0.94
74_V	83_A	0.583	0.94
210_F	419_H	0.582	0.94
337_L	345_I	0.581	0.94
122_R	242_L	0.581	0.94
215_Y	383_S	0.580	0.94
11_S	150_I	0.579	0.94
396_P	412_G	0.579	0.94
344_A	350_A	0.578	0.94
32_G	107_W	0.577	0.94
66_L	102_I	0.577	0.94
189_I	451_L	0.576	0.94
33_L	141_R	0.574	0.94
386_L	389_A	0.573	0.93
106_G	109_K	0.573	0.93
6_I	147_N	0.572	0.93
307_A	311_G	0.572	0.93
397_L	413_L	0.572	0.93
205_N	208_S	0.570	0.93
96_E	100_L	0.570	0.93
323_M	367_M	0.569	0.93
200_E	203_E	0.569	0.93
288_A	401_A	0.568	0.93
16_R	48_M	0.568	0.93
451_L	454_M	0.567	0.93
46_P	49_E	0.567	0.93
204_D	425_S	0.566	0.93
71_V	100_L	0.566	0.93
263_I	266_S	0.566	0.93
187_I	192_I	0.565	0.93
77_L	81_I	0.565	0.93
6_I	77_L	0.564	0.93
360_A	369_I	0.562	0.93
40_N	69_S	0.562	0.93
304_S	308_S	0.562	0.93
301_L	313_P	0.562	0.93
8_G	169_E	0.561	0.93
309_R	316_A	0.560	0.93
211_P	430_Y	0.559	0.93
78_D	160_K	0.558	0.93
238_S	259_Y	0.556	0.92
158_R	227_L	0.556	0.92
228_E	253_Q	0.554	0.92
179_E	424_R	0.554	0.92
334_G	343_Q	0.554	0.92
432_S	436_P	0.553	0.92
393_L	396_P	0.552	0.92
331_R	395_F	0.552	0.92
327_F	346_S	0.552	0.92
208_S	423_L	0.550	0.92
326_T	373_L	0.549	0.92
264_I	392_L	0.548	0.92
329_L	373_L	0.546	0.92
300_E	303_L	0.546	0.92
348_V	372_A	0.544	0.92
18_F	26_A	0.543	0.92
42_F	67_P	0.543	0.92
439_L	442_L	0.541	0.91
173_N	178_E	0.540	0.91
452_W	455_K	0.540	0.91
204_D	424_R	0.540	0.91
453_K	456_K	0.539	0.91
214_L	383_S	0.539	0.91
25_A	44_L	0.538	0.91
417_L	431_L	0.536	0.91
287_V	401_A	0.536	0.91
289_L	296_M	0.535	0.91
308_S	364_S	0.535	0.91
421_A	435_A	0.534	0.91
83_A	90_V	0.534	0.91
135_N	138_L	0.534	0.91
120_V	124_P	0.532	0.91
279_S	377_A	0.532	0.91
118_E	275_A	0.532	0.91
176_L	179_E	0.532	0.91
133_R	152_S	0.530	0.91
401_A	405_G	0.529	0.90
332_E	336_R	0.528	0.90
456_K	459_S	0.528	0.90
61_L	65_L	0.527	0.90
11_S	136_T	0.527	0.90
409_I	413_L	0.527	0.90
179_E	202_I	0.527	0.90
362_L	369_I	0.527	0.90
340_P	344_A	0.526	0.90
48_M	51_S	0.525	0.90
212_Q	425_S	0.523	0.90
299_T	303_L	0.523	0.90
304_S	366_I	0.523	0.90
444_D	447_I	0.523	0.90
50_L	53_E	0.520	0.90
45_K	67_P	0.520	0.90
411_L	418_I	0.517	0.89
4_K	9_N	0.517	0.89
105_R	162_D	0.517	0.89
81_I	84_I	0.517	0.89
260_Q	268_L	0.516	0.89
345_I	375_A	0.516	0.89
34_V	106_G	0.516	0.89
289_L	297_I	0.516	0.89
43_I	46_P	0.515	0.89
339_K	344_A	0.515	0.89
305_I	308_S	0.515	0.89
80_I	84_I	0.515	0.89
39_I	43_I	0.515	0.89
280_L	284_A	0.515	0.89
340_P	346_S	0.514	0.89
424_R	429_P	0.513	0.89
286_Y	316_A	0.513	0.89
3_L	81_I	0.512	0.89
196_G	199_E	0.510	0.89
418_I	422_S	0.510	0.89
150_I	234_L	0.509	0.89
327_F	379_F	0.509	0.89
431_L	435_A	0.509	0.89
43_I	89_T	0.509	0.89
297_I	300_E	0.509	0.89
60_E	63_E	0.509	0.89
193_L	223_A	0.508	0.89
374_T	394_R	0.508	0.89
442_L	449_A	0.508	0.89
337_L	341_I	0.507	0.89
11_S	164_A	0.507	0.89
364_S	367_M	0.507	0.89
440_K	459_S	0.506	0.88
220_D	259_Y	0.506	0.88
400_L	411_L	0.506	0.88
112_V	129_T	0.506	0.88
44_L	67_P	0.506	0.88
358_V	363_V	0.505	0.88
432_S	435_A	0.505	0.88
48_M	67_P	0.505	0.88
63_E	73_E	0.504	0.88
252_F	386_L	0.504	0.88
70_E	88_D	0.502	0.88
171_I	177_V	0.502	0.88
221_V	225_A	0.502	0.88
194_D	235_V	0.501	0.88
7_F	13_L	0.501	0.88
303_L	306_A	0.501	0.88
222_V	226_L	0.501	0.88
209_P	392_L	0.500	0.88
444_D	448_R	0.500	0.88

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3hh1A	2	0.2261	20.5	0.98	Contact Map
4g3oA	1	0.0957	17.1	0.981	Contact Map
3kpeA	3	0.1065	16.4	0.981	Contact Map
2qx0A	2	0.1587	12.8	0.982	Contact Map
1rybA	1	0.1522	11.9	0.982	Contact Map
1xtiA	1	0.35	11.5	0.982	Contact Map
1t5iA	1	0.3326	8.8	0.983	Contact Map
2k8yA	1	0.3109	8.5	0.983	Contact Map
1cbkA	2	0.163	8.5	0.983	Contact Map
4bemA	3	0.1761	8.4	0.983	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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