GREMLIN Database
OPT - OPT oligopeptide transporter protein
PFAM: PF03169 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 615 (582)
Sequences: 9459 (5667)
Seq/√Len: 234.9
META: 0.633

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
416_G419_L3.9871.00
4_L8_L3.9501.00
415_F419_L3.8311.00
416_G420_P3.6001.00
507_A511_E3.1911.00
169_G173_G3.1731.00
159_R163_L2.9951.00
415_F418_L2.9401.00
166_A169_G2.9031.00
170_G173_G2.8711.00
266_I269_I2.8691.00
458_R462_I2.8631.00
119_L354_G2.5781.00
171_F174_G2.5761.00
267_S270_L2.5601.00
160_A164_L2.5041.00
176_L180_L2.4971.00
230_L578_W2.4951.00
169_G174_G2.4561.00
415_F420_P2.4501.00
364_A368_F2.4471.00
159_R162_F2.4291.00
160_A163_L2.3951.00
266_I270_L2.3951.00
166_A173_G2.3371.00
414_I418_L2.2921.00
344_R458_R2.2751.00
237_L571_F2.2441.00
366_L370_F2.2391.00
205_G208_L2.2311.00
25_G88_I2.1571.00
362_A366_L2.1211.00
577_R581_D2.1201.00
320_L324_R2.1091.00
74_I463_A2.0931.00
371_F374_P2.0791.00
575_L579_L2.0641.00
413_L416_G2.0591.00
162_F166_A2.0561.00
306_A309_L2.0401.00
513_G516_G1.9911.00
306_A310_K1.9861.00
578_W582_R1.9851.00
163_L166_A1.9791.00
8_L12_L1.9791.00
174_G178_L1.9501.00
415_F421_G1.9471.00
191_T195_P1.9241.00
546_G550_L1.9221.00
362_A367_P1.9211.00
414_I419_L1.9141.00
526_I530_L1.9081.00
349_W353_I1.9061.00
526_I529_A1.8721.00
587_E591_R1.8721.00
111_L469_L1.8651.00
167_F170_G1.8641.00
55_K61_G1.8631.00
163_L167_F1.8601.00
207_G210_K1.8601.00
166_A174_G1.8571.00
192_W195_P1.8551.00
65_I146_L1.8531.00
365_L369_L1.8471.00
311_T315_G1.8301.00
347_P350_W1.8141.00
418_L421_G1.8131.00
265_N268_A1.8091.00
265_N269_I1.7931.00
234_A571_F1.7861.00
188_S191_T1.7721.00
523_G527_G1.7701.00
309_L312_I1.7691.00
258_A261_Y1.7231.00
234_A238_A1.6991.00
170_G174_G1.6861.00
242_L246_V1.6861.00
267_S271_A1.6761.00
162_F165_I1.6691.00
314_S318_S1.6621.00
352_L356_V1.6621.00
314_S317_K1.6621.00
177_P180_L1.6491.00
529_A533_V1.6471.00
158_S162_F1.6461.00
7_V466_I1.6331.00
257_W262_L1.6281.00
439_I468_V1.6271.00
162_F596_L1.6261.00
310_K314_S1.6211.00
24_L220_A1.6171.00
115_L465_L1.6161.00
340_M343_E1.6161.00
222_L576_I1.6091.00
11_L470_V1.6021.00
362_A370_F1.6001.00
259_P263_P1.5941.00
315_G318_S1.5891.00
70_I463_A1.5891.00
173_G178_L1.5791.00
528_G532_G1.5711.00
273_A277_N1.5631.00
532_G535_L1.5591.00
307_K319_A1.5591.00
318_S321_A1.5571.00
243_A560_M1.5461.00
174_G177_P1.5451.00
319_A322_A1.5451.00
531_I535_L1.5401.00
318_S322_A1.5381.00
173_G176_L1.5341.00
253_F256_G1.5311.00
164_L168_G1.5251.00
243_A279_V1.5241.00
54_P62_P1.5221.00
188_S192_W1.5221.00
545_R549_F1.5151.00
364_A367_P1.5141.00
182_P186_G1.5121.00
258_A262_L1.5101.00
358_A362_A1.5071.00
530_L534_V1.4941.00
587_E590_E1.4861.00
366_L369_L1.4791.00
527_G531_I1.4791.00
367_P370_F1.4741.00
157_K160_A1.4731.00
165_I169_G1.4681.00
5_R67_E1.4581.00
257_W261_Y1.4561.00
533_V537_L1.4561.00
97_L101_P1.4551.00
161_K165_I1.4531.00
312_I315_G1.4481.00
359_L363_I1.4471.00
205_G210_K1.4451.00
128_L393_G1.4451.00
520_L523_G1.4441.00
494_G497_A1.4371.00
194_F197_N1.4351.00
414_I420_P1.4341.00
182_P187_F1.4341.00
138_E400_G1.4341.00
168_G173_G1.4321.00
241_V246_V1.4301.00
362_A365_L1.4281.00
96_I507_A1.4271.00
256_G261_Y1.4191.00
143_A452_L1.4121.00
546_G549_F1.4101.00
2_L462_I1.4091.00
537_L541_F1.4071.00
477_P481_L1.4041.00
417_L420_P1.4021.00
542_P545_R1.3981.00
353_I357_L1.3891.00
307_K311_T1.3871.00
42_S46_L1.3861.00
186_G189_W1.3861.00
514_V517_G1.3811.00
161_K164_L1.3761.00
363_I367_P1.3751.00
184_L187_F1.3741.00
206_L209_A1.3731.00
241_V245_G1.3701.00
186_G190_V1.3681.00
278_Y282_I1.3661.00
308_L311_T1.3651.00
313_L316_F1.3641.00
230_L575_L1.3631.00
306_A312_I1.3491.00
547_K550_L1.3431.00
309_L315_G1.3371.00
160_A166_A1.3351.00
310_K317_K1.3341.00
159_R165_I1.3301.00
144_E147_K1.3291.00
289_V529_A1.3281.00
362_A369_L1.3271.00
392_A402_N1.3261.00
266_I271_A1.3261.00
187_F190_V1.3231.00
244_W275_W1.3131.00
363_I366_L1.3121.00
190_V194_F1.3101.00
167_F171_F1.3041.00
521_P524_L1.3021.00
320_L323_L1.2971.00
11_L466_I1.2971.00
171_F175_L1.2961.00
252_Y257_W1.2921.00
490_G495_S1.2911.00
308_L312_I1.2881.00
583_R586_P1.2881.00
312_I319_A1.2881.00
182_P189_W1.2851.00
182_P185_S1.2841.00
253_F257_W1.2831.00
413_L420_P1.2801.00
114_G468_V1.2781.00
118_V468_V1.2771.00
107_F473_L1.2691.00
306_A311_T1.2651.00
532_G536_I1.2611.00
158_S161_K1.2531.00
360_V364_A1.2511.00
310_K313_L1.2461.00
181_F185_S1.2371.00
316_F319_A1.2351.00
311_T314_S1.2311.00
361_L366_L1.2291.00
205_G209_A1.2271.00
97_L100_W1.2271.00
188_S193_I1.2271.00
361_L365_L1.2241.00
185_S192_W1.2111.00
186_G192_W1.2081.00
167_F173_G1.2011.00
570_I573_G1.2001.00
15_V470_V1.1991.00
289_V533_V1.1991.00
363_I368_F1.1971.00
486_Y489_G1.1961.00
164_L167_F1.1941.00
264_Y273_A1.1941.00
108_L112_L1.1931.00
606_L610_L1.1911.00
103_F107_F1.1881.00
358_A363_I1.1871.00
307_K310_K1.1861.00
309_L313_L1.1791.00
226_Y593_G1.1681.00
264_Y268_A1.1681.00
315_G319_A1.1671.00
255_G261_Y1.1661.00
545_R550_L1.1651.00
228_V232_V1.1651.00
361_L367_P1.1641.00
279_V283_G1.1621.00
359_L382_L1.1601.00
316_F320_L1.1591.00
308_L319_A1.1591.00
259_P262_L1.1561.00
413_L418_L1.1561.00
265_N270_L1.1561.00
215_W568_L1.1551.00
257_W263_P1.1541.00
268_A271_A1.1521.00
380_L418_L1.1511.00
450_G460_Q1.1511.00
359_L362_A1.1501.00
528_G531_I1.1391.00
38_A75_A1.1391.00
469_L473_L1.1371.00
413_L419_L1.1331.00
372_G376_W1.1311.00
157_K161_K1.1301.00
11_L15_V1.1271.00
373_L376_W1.1241.00
350_W354_G1.1171.00
389_A440_A1.1141.00
183_A186_G1.1091.00
293_I533_V1.1091.00
14_G471_G1.1081.00
183_A187_F1.1061.00
247_L279_V1.1061.00
260_A263_P1.1061.00
346_L350_W1.1051.00
473_L477_P1.1031.00
363_I369_L1.1031.00
240_G567_T1.1021.00
4_L7_V1.1011.00
474_V478_V1.0991.00
319_A323_L1.0931.00
312_I316_F1.0911.00
310_K315_G1.0901.00
49_L61_G1.0901.00
73_T460_Q1.0831.00
189_W195_P1.0821.00
310_K316_F1.0781.00
188_S195_P1.0771.00
43_M47_R1.0761.00
308_L316_F1.0721.00
308_L318_S1.0721.00
254_G257_W1.0701.00
317_K321_A1.0691.00
492_G495_S1.0681.00
163_L170_G1.0671.00
181_F187_F1.0661.00
189_W193_I1.0651.00
309_L316_F1.0621.00
223_G600_L1.0621.00
185_S189_W1.0601.00
524_L527_G1.0601.00
414_I417_L1.0541.00
191_T194_F1.0531.00
257_W260_A1.0501.00
311_T316_F1.0491.00
168_G172_V1.0471.00
13_L41_I1.0461.00
184_L190_V1.0461.00
317_K320_L1.0441.00
443_L447_L1.0431.00
255_G260_A1.0431.00
230_L234_A1.0411.00
365_L370_F1.0391.00
252_Y255_G1.0361.00
323_L326_A1.0321.00
179_Y182_P1.0281.00
42_S68_N1.0261.00
181_F186_G1.0251.00
237_L241_V1.0251.00
15_V474_V1.0231.00
255_G259_P1.0201.00
278_Y281_Y1.0201.00
485_A488_F1.0191.00
313_L317_K1.0191.00
402_N441_G1.0191.00
535_L556_F1.0131.00
252_Y256_G1.0101.00
362_A378_A1.0101.00
174_G179_Y1.0091.00
19_A478_V1.0051.00
187_F191_T1.0041.00
542_P547_K1.0031.00
465_L469_L1.0031.00
187_F192_W1.0001.00
308_L314_S1.0001.00
264_Y267_S0.9991.00
348_M352_L0.9991.00
159_R166_A0.9951.00
180_L184_L0.9941.00
375_L379_L0.9891.00
311_T318_S0.9861.00
255_G258_A0.9841.00
192_W196_T0.9781.00
191_T196_T0.9781.00
2_L459_K0.9771.00
361_L370_F0.9761.00
256_G262_L0.9751.00
9_L45_L0.9741.00
185_S188_S0.9711.00
189_W192_W0.9711.00
607_M610_L0.9691.00
143_A449_T0.9681.00
190_V193_I0.9601.00
404_V438_A0.9591.00
166_A596_L0.9591.00
237_L568_L0.9551.00
545_R548_R0.9531.00
264_Y269_I0.9491.00
168_G174_G0.9481.00
586_P589_A0.9431.00
242_L247_L0.9411.00
244_W248_I0.9371.00
459_K462_I0.9321.00
176_L179_Y0.9301.00
35_S72_Q0.9281.00
568_L572_V0.9271.00
280_R283_G0.9251.00
120_F386_F0.9241.00
184_L192_W0.9241.00
6_A70_I0.9241.00
256_G259_P0.9231.00
173_G177_P0.9221.00
167_F174_G0.9181.00
254_G259_P0.9171.00
371_F376_W0.9151.00
159_R164_L0.9151.00
306_A319_A0.9151.00
63_F71_V0.9131.00
201_A204_F0.9131.00
175_L178_L0.9121.00
142_T449_T0.9071.00
314_S319_A0.9071.00
322_A325_A0.9061.00
166_A171_F0.9051.00
542_P546_G0.9051.00
316_F326_A0.9041.00
519_N522_W0.9021.00
134_L397_G0.9001.00
495_S499_P0.8981.00
103_F477_P0.8970.99
233_A574_G0.8960.99
417_L421_G0.8960.99
111_L472_A0.8950.99
34_A79_G0.8930.99
522_W525_L0.8920.99
272_E276_S0.8910.99
2_L7_V0.8890.99
3_T6_A0.8880.99
308_L315_G0.8860.99
306_A315_G0.8810.99
163_L174_G0.8800.99
341_R344_R0.8800.99
41_I45_L0.8800.99
372_G375_L0.8800.99
173_G180_L0.8790.99
594_V598_S0.8790.99
504_T507_A0.8790.99
544_R548_R0.8780.99
309_L314_S0.8760.99
307_K313_L0.8700.99
206_L210_K0.8700.99
178_L181_F0.8680.99
389_A436_A0.8660.99
68_N71_V0.8630.99
188_S194_F0.8630.99
228_V400_G0.8620.99
265_N271_A0.8620.99
313_L319_A0.8620.99
564_L568_L0.8610.99
17_F38_A0.8600.99
126_R131_D0.8580.99
269_I273_A0.8570.99
2_L6_A0.8570.99
190_V195_P0.8530.99
488_F491_A0.8510.99
181_F184_L0.8500.99
275_W280_R0.8480.99
531_I536_I0.8460.99
578_W581_D0.8450.99
182_P188_S0.8440.99
322_A326_A0.8430.99
254_G261_Y0.8420.99
255_G263_P0.8420.99
165_I168_G0.8410.99
5_R49_L0.8410.99
254_G258_A0.8400.99
481_L613_F0.8400.99
568_L571_F0.8390.99
256_G260_A0.8340.99
68_N150_H0.8330.99
87_V110_A0.8310.99
318_S323_L0.8310.99
569_P572_V0.8290.99
66_L455_A0.8270.99
151_K154_G0.8270.99
74_I467_G0.8260.99
254_G260_A0.8250.99
586_P590_E0.8250.99
513_G517_G0.8230.99
360_V368_F0.8220.99
55_K62_P0.8220.99
315_G320_L0.8210.99
306_A316_F0.8200.99
544_R549_F0.8200.99
307_K315_G0.8180.99
489_G504_T0.8170.99
306_A313_L0.8160.99
361_L364_A0.8140.99
487_G495_S0.8120.99
160_A167_F0.8120.99
610_L613_F0.8110.99
308_L322_A0.8110.99
112_L362_A0.8110.99
264_Y270_L0.8090.99
42_S71_V0.8080.99
525_L528_G0.8080.99
309_L319_A0.8060.99
98_G102_G0.8040.99
341_R345_D0.8030.99
480_N484_K0.8000.99
536_I539_D0.7980.99
307_K320_L0.7980.99
408_T434_C0.7960.99
519_N523_G0.7940.99
178_L184_L0.7930.99
230_L571_F0.7920.99
64_T67_E0.7910.99
252_Y259_P0.7900.99
314_S323_L0.7890.99
180_L186_G0.7890.99
43_M46_L0.7880.99
426_A430_G0.7870.99
99_L102_G0.7870.99
21_N25_G0.7850.99
312_I318_S0.7820.99
179_Y190_V0.7810.99
49_L54_P0.7780.99
416_G426_A0.7750.99
361_L368_F0.7730.98
607_M611_I0.7730.98
488_F495_S0.7720.98
184_L189_W0.7700.98
187_F194_F0.7690.98
5_R62_P0.7680.98
107_F111_L0.7680.98
271_A275_W0.7680.98
69_N72_Q0.7680.98
185_S190_V0.7660.98
414_I421_G0.7660.98
522_W527_G0.7650.98
90_T427_L0.7630.98
534_V538_L0.7630.98
258_A263_P0.7620.98
585_R589_A0.7620.98
484_K487_G0.7600.98
185_S191_T0.7600.98
311_T319_A0.7600.98
487_G496_N0.7590.98
365_L368_F0.7580.98
290_G553_P0.7560.98
187_F213_F0.7520.98
572_V576_I0.7520.98
193_I196_T0.7500.98
534_V537_L0.7480.98
339_L343_E0.7480.98
293_I536_I0.7470.98
609_V613_F0.7470.98
89_F92_P0.7460.98
552_P555_A0.7420.98
174_G607_M0.7420.98
307_K314_S0.7420.98
180_L187_F0.7410.98
542_P550_L0.7410.98
234_A575_L0.7400.98
270_L273_A0.7400.98
575_L578_W0.7370.98
520_L524_L0.7360.98
532_G539_D0.7350.98
285_G289_V0.7350.98
115_L358_A0.7340.98
359_L365_L0.7340.98
256_G263_P0.7330.98
574_G577_R0.7320.98
172_V176_L0.7310.98
85_A89_F0.7280.98
181_F188_S0.7280.98
139_G449_T0.7270.98
245_G249_P0.7260.98
10_G74_I0.7260.98
579_L584_R0.7260.98
416_G421_G0.7250.98
213_F245_G0.7240.98
584_R588_W0.7230.98
292_I306_A0.7230.98
542_P548_R0.7230.98
364_A370_F0.7220.98
551_P557_A0.7220.98
581_D586_P0.7190.98
139_G445_Q0.7180.98
169_G178_L0.7160.98
520_L525_L0.7160.98
528_G535_L0.7160.98
183_A188_S0.7150.98
585_R588_W0.7150.98
184_L188_S0.7140.97
359_L370_F0.7140.97
98_G101_P0.7120.97
160_A165_I0.7120.97
367_P375_L0.7110.97
174_G180_L0.7110.97
281_Y286_A0.7110.97
496_N499_P0.7100.97
162_F592_Y0.7100.97
193_I197_N0.7100.97
535_L539_D0.7090.97
342_T345_D0.7090.97
13_L45_L0.7090.97
596_L600_L0.7060.97
286_A557_A0.7060.97
158_S163_L0.7060.97
544_R550_L0.7050.97
307_K322_A0.7050.97
351_V354_G0.7040.97
412_L426_A0.7040.97
358_A361_L0.7040.97
18_G22_A0.7030.97
252_Y258_A0.7020.97
307_K312_I0.7020.97
477_P480_N0.7020.97
411_T433_V0.7020.97
359_L367_P0.7020.97
455_A459_K0.7020.97
567_T570_I0.7020.97
179_Y184_L0.7010.97
482_L498_L0.7010.97
186_G191_T0.7010.97
182_P190_V0.7000.97
235_S556_F0.7000.97
289_V293_I0.6990.97
422_G425_A0.6960.97
86_G92_P0.6960.97
396_V441_G0.6960.97
520_L527_G0.6950.97
581_D590_E0.6940.97
599_G603_G0.6910.97
108_L111_L0.6910.97
44_A160_A0.6890.97
306_A314_S0.6880.97
252_Y263_P0.6860.97
307_K318_S0.6860.97
536_I553_P0.6850.97
486_Y490_G0.6850.97
253_F258_A0.6830.97
470_V474_V0.6830.97
247_L282_I0.6830.97
544_R547_K0.6830.97
584_R587_E0.6810.97
344_R347_P0.6810.97
166_A170_G0.6810.97
66_L454_G0.6810.97
468_V472_A0.6800.97
523_G526_I0.6780.97
489_G494_G0.6780.97
340_M344_R0.6780.97
9_L46_L0.6770.97
310_K318_S0.6770.97
175_L179_Y0.6770.97
478_V482_L0.6760.97
576_I580_V0.6760.97
38_A42_S0.6740.96
240_G564_L0.6740.96
338_A344_R0.6730.96
5_R64_T0.6700.96
154_G161_K0.6680.96
275_W278_Y0.6670.96
125_R345_D0.6670.96
306_A318_S0.6650.96
551_P556_F0.6630.96
352_L355_L0.6630.96
536_I540_V0.6630.96
601_I604_E0.6610.96
314_S322_A0.6610.96
494_G499_P0.6610.96
388_F411_T0.6600.96
490_G494_G0.6600.96
311_T317_K0.6590.96
321_A324_R0.6590.96
140_T452_L0.6580.96
97_L102_G0.6580.96
157_K162_F0.6570.96
339_L344_R0.6570.96
171_F607_M0.6560.96
339_L342_T0.6550.96
194_F198_V0.6540.96
106_I476_G0.6540.96
110_A472_A0.6530.96
552_P559_G0.6530.96
35_S142_T0.6530.96
25_G28_A0.6520.96
35_S449_T0.6520.96
226_Y580_V0.6510.96
353_I356_V0.6500.96
396_V404_V0.6500.96
179_Y186_G0.6500.96
73_T450_G0.6490.96
314_S321_A0.6480.96
76_S80_S0.6480.96
66_L69_N0.6480.96
63_F68_N0.6450.95
279_V282_I0.6450.95
87_V91_L0.6450.95
130_V345_D0.6430.95
335_A338_A0.6420.95
415_F429_V0.6410.95
121_A444_L0.6390.95
521_P527_G0.6380.95
112_L358_A0.6370.95
214_G565_S0.6360.95
563_P566_L0.6360.95
583_R587_E0.6350.95
175_L180_L0.6350.95
527_G530_L0.6350.95
393_G444_L0.6340.95
86_G89_F0.6340.95
189_W194_F0.6340.95
182_P192_W0.6330.95
168_G171_F0.6330.95
487_G490_G0.6330.95
442_D446_D0.6320.95
13_L42_S0.6310.95
24_L31_T0.6300.95
241_V571_F0.6290.95
115_L469_L0.6290.95
6_A10_G0.6270.95
562_L566_L0.6270.95
527_G532_G0.6260.95
571_F575_L0.6260.95
361_L369_L0.6250.95
69_N73_T0.6250.95
594_V601_I0.6240.95
316_F323_L0.6240.95
348_M351_V0.6240.95
394_Y398_L0.6210.94
309_L323_L0.6180.94
232_V399_T0.6180.94
351_V355_L0.6180.94
608_G612_A0.6170.94
235_S238_A0.6160.94
240_G243_A0.6140.94
250_L527_G0.6130.94
180_L185_S0.6120.94
280_R284_A0.6110.94
162_F173_G0.6110.94
360_V363_I0.6110.94
184_L195_P0.6100.94
179_Y183_A0.6100.94
611_I614_L0.6100.94
360_V365_L0.6100.94
214_G218_S0.6100.94
187_F193_I0.6090.94
231_R539_D0.6090.94
505_L508_A0.6080.94
80_S442_D0.6080.94
309_L325_A0.6060.94
363_I370_F0.6030.94
466_I470_V0.6020.93
135_P140_T0.6020.93
446_D464_Q0.6010.93
159_R167_F0.5990.93
208_L213_F0.5990.93
366_L432_V0.5990.93
502_Q513_G0.5980.93
177_P181_F0.5970.93
125_R447_L0.5970.93
195_P198_V0.5960.93
313_L320_L0.5960.93
272_E275_W0.5950.93
163_L173_G0.5920.93
341_R456_T0.5920.93
80_S439_I0.5910.93
362_A368_F0.5900.93
309_L320_L0.5900.93
479_L483_N0.5890.93
379_L383_V0.5890.93
315_G322_A0.5880.93
337_A340_M0.5880.93
488_F494_G0.5870.93
5_R63_F0.5860.93
493_D496_N0.5860.93
358_A364_A0.5820.92
516_G519_N0.5810.92
502_Q505_L0.5810.92
527_G536_I0.5780.92
360_V369_L0.5770.92
228_V570_I0.5750.92
283_G291_G0.5730.92
219_P222_L0.5730.92
373_L377_A0.5730.92
190_V196_T0.5720.92
360_V366_L0.5710.92
46_L71_V0.5700.92
173_G179_Y0.5690.91
346_L462_I0.5680.91
443_L464_Q0.5680.91
498_L501_P0.5680.91
610_L614_L0.5670.91
309_L318_S0.5660.91
313_L318_S0.5650.91
358_A370_F0.5650.91
184_L191_T0.5650.91
405_S502_Q0.5650.91
384_L411_T0.5650.91
419_L422_G0.5640.91
378_A382_L0.5640.91
311_T322_A0.5640.91
129_V451_Y0.5630.91
360_V367_P0.5630.91
588_W592_Y0.5630.91
187_F195_P0.5630.91
370_F373_L0.5610.91
541_F545_R0.5610.91
91_L106_I0.5600.91
170_G176_L0.5600.91
176_L182_P0.5590.91
357_L361_L0.5590.91
508_A511_E0.5580.91
533_V536_I0.5580.91
120_F382_L0.5580.91
94_L424_A0.5560.90
175_L181_F0.5550.90
541_F544_R0.5550.90
283_G560_M0.5540.90
478_V481_L0.5530.90
86_G90_T0.5520.90
224_V597_A0.5520.90
521_P525_L0.5520.90
138_E445_Q0.5510.90
539_D552_P0.5500.90
334_D337_A0.5500.90
538_L551_P0.5500.90
491_A494_G0.5500.90
88_I92_P0.5500.90
116_L382_L0.5490.90
580_V588_W0.5490.90
535_L538_L0.5490.90
477_P482_L0.5480.90
282_I527_G0.5470.90
318_S325_A0.5460.90
500_A503_A0.5460.90
141_A227_I0.5450.90
336_H339_L0.5450.90
502_Q561_Y0.5450.90
25_G31_T0.5420.89
242_L531_I0.5410.89
511_E519_N0.5390.89
371_F375_L0.5380.89
488_F493_D0.5380.89
358_A365_L0.5370.89
334_D340_M0.5370.89
240_G558_L0.5360.89
243_A247_L0.5360.89
111_L473_L0.5360.89
126_R345_D0.5340.89
215_W569_P0.5320.88
284_A291_G0.5310.88
263_P269_I0.5310.88
275_W279_V0.5310.88
54_P61_G0.5300.88
102_G105_Q0.5300.88
34_A37_P0.5300.88
364_A369_L0.5300.88
246_V250_L0.5300.88
192_W197_N0.5280.88
283_G295_L0.5260.88
171_F178_L0.5260.88
17_F20_A0.5250.88
65_I147_K0.5250.88
359_L366_L0.5250.88
140_T451_Y0.5230.88
347_P354_G0.5230.88
45_L48_L0.5220.88
139_G455_A0.5200.87
28_A570_I0.5200.87
349_W352_L0.5200.87
233_A237_L0.5190.87
103_F476_G0.5190.87
254_G263_P0.5180.87
308_L313_L0.5180.87
115_L119_L0.5180.87
409_I509_V0.5170.87
21_N32_V0.5170.87
107_F476_G0.5170.87
106_I480_N0.5160.87
315_G321_A0.5160.87
23_Y29_G0.5160.87
348_M353_I0.5160.87
33_S37_P0.5160.87
42_S45_L0.5160.87
24_L28_A0.5140.87
183_A190_V0.5130.87
471_G475_I0.5120.87
204_F207_G0.5120.87
291_G294_T0.5110.86
133_K451_Y0.5110.86
86_G91_L0.5100.86
178_L182_P0.5090.86
157_K165_I0.5090.86
15_V18_G0.5080.86
485_A495_S0.5070.86
527_G535_L0.5070.86
442_D464_Q0.5070.86
265_N273_A0.5070.86
540_V552_P0.5060.86
8_L49_L0.5060.86
109_I428_M0.5060.86
75_A81_L0.5050.86
158_S165_I0.5050.86
161_K166_A0.5040.86
69_N146_L0.5030.86
73_T76_S0.5030.86
198_V202_Q0.5030.86
246_V249_P0.5030.86
49_L55_K0.5030.86
507_A510_A0.5020.85
6_A67_E0.5020.85
355_L382_L0.5010.85
316_F322_A0.5010.85
31_T40_V0.5010.85
504_T508_A0.5010.85
189_W196_T0.5000.85
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3nd0A 2 0.2146 13 0.977 Contact Map
4eneA 2 0.2163 11.4 0.978 Contact Map
3rlbA 1 0.2764 9.2 0.979 Contact Map
4tkrA 2 0.2829 7.4 0.98 Contact Map
1kf6D 2 0.1935 2.9 0.983 Contact Map
2l35A 2 0.0439 2.4 0.984 Contact Map
2l34A 2 0.0439 2.3 0.984 Contact Map
1v54K 1 0.0455 2 0.985 Contact Map
4p6vB 1 0.0943 2 0.985 Contact Map
4w6vA 1 0.2065 1.8 0.985 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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