Alg6_Alg8 - PFAM28P - GREMLIN Contacts

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Alg6_Alg8 - ALG6, ALG8 glycosyltransferase family

PFAM:	PF03155	Sequences: ATLLKLLLPPMYRSTDFEVHRHWLAITHSLPISQWYFNYYEDLSYWTLDYPPLFAYFEWLLGQVAAKFVDPEMVALHTSRGYESWSTKLFMRLTVIVSDLLLYYPAVLLFSSIAALLILLSPGLLLIDHGHFQYNGFLLGLLLLSIAALRQGRDLLLGAFLFALLLNFKHMYLYYAPAYFVYLLRKYCLKPGRFGFLRLIKLGLVVIATFALSFGPFLYGQLPQVLSRLFPFSRGLFHAYWANFWCLYNVLDKVLIFASMTDTSFAVLPSILPLLTFLLTLLAQLPSLIKLWRKPTPRLFLLALTLCSLAFFLFGWHVHEKAILLVLLPLSLLALEDPRDARAFLWLSVVGHFSLFPLLFTDGLLLIKVVLTLLWLILSLLSLSRLAPKSESPVFLLDRLELLYLLGLIGMLILHCLLHLLVFGPPPARYPFLPLMLTSVYCAFGVFYSWLLW	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_10
Length:	453 (441)
Sequences:	830 (589)
Seq/√Len:	28.1
META:	0.108

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
283_A	310_A	4.603	1.00
160_F	205_V	4.582	1.00
65_A	74_V	4.453	1.00
244_F	314_F	4.362	1.00
145_S	179_Y	4.308	1.00
167_N	213_S	3.627	1.00
214_F	225_V	3.598	1.00
248_Y	254_V	3.530	1.00
415_H	419_H	3.513	1.00
90_F	94_T	3.485	1.00
149_L	158_G	3.419	1.00
183_L	202_L	3.316	1.00
146_I	304_L	3.309	1.00
354_S	443_A	3.297	1.00
308_S	326_V	3.129	1.00
137_F	168_F	3.073	1.00
148_A	161_L	2.952	1.00
59_W	63_Q	2.952	1.00
244_F	444_F	2.910	1.00
154_D	186_K	2.906	1.00
155_L	205_V	2.900	1.00
167_N	214_F	2.881	1.00
249_N	265_F	2.862	1.00
323_I	326_V	2.780	1.00
368_K	415_H	2.777	1.00
17_F	87_T	2.744	1.00
70_D	73_M	2.739	1.00
172_Y	175_Y	2.732	1.00
141_L	168_F	2.688	1.00
105_P	144_L	2.686	1.00
167_N	210_F	2.603	0.99
73_M	87_T	2.569	0.99
138_L	172_Y	2.566	0.99
42_D	80_R	2.514	0.99
166_L	210_F	2.505	0.99
237_F	249_N	2.365	0.99
8_L	125_L	2.344	0.99
180_F	206_V	2.337	0.99
284_Q	310_A	2.274	0.98
41_E	76_L	2.214	0.98
57_F	98_S	2.193	0.98
410_G	441_Y	2.139	0.98
107_V	143_L	2.025	0.97
149_L	182_Y	2.007	0.96
326_V	329_P	1.996	0.96
43_L	47_T	1.974	0.96
327_L	351_G	1.947	0.96
199_L	203_G	1.935	0.96
125_L	371_L	1.928	0.96
171_M	174_Y	1.926	0.95
166_L	176_A	1.917	0.95
425_P	434_P	1.885	0.95
154_D	158_G	1.881	0.95
214_F	229_L	1.863	0.95
283_A	286_P	1.854	0.94
29_S	76_L	1.854	0.94
224_Q	227_S	1.815	0.94
284_Q	307_C	1.796	0.93
273_P	316_W	1.780	0.93
298_R	336_E	1.776	0.93
432_F	436_M	1.769	0.93
349_V	376_L	1.728	0.92
159_A	206_V	1.718	0.92
60_L	64_V	1.699	0.91
115_A	119_L	1.697	0.91
171_M	325_L	1.696	0.91
72_E	75_A	1.695	0.91
181_V	288_L	1.687	0.91
111_S	429_R	1.668	0.91
103_Y	119_L	1.666	0.90
15_T	19_V	1.645	0.90
178_A	202_L	1.627	0.89
26_I	32_I	1.627	0.89
308_S	325_L	1.613	0.89
138_L	168_F	1.612	0.89
123_G	327_L	1.590	0.88
232_F	316_W	1.588	0.88
47_T	54_F	1.587	0.88
65_A	73_M	1.581	0.88
240_Y	432_F	1.575	0.88
325_L	329_P	1.572	0.88
28_H	63_Q	1.553	0.87
165_L	172_Y	1.545	0.87
129_H	136_G	1.545	0.87
16_D	23_W	1.533	0.86
198_R	201_K	1.530	0.86
26_I	123_G	1.525	0.86
28_H	62_G	1.519	0.86
232_F	273_P	1.519	0.86
252_D	266_A	1.516	0.86
123_G	351_G	1.515	0.86
15_T	20_H	1.510	0.85
73_M	82_Y	1.496	0.85
18_E	21_R	1.493	0.85
149_L	179_Y	1.491	0.85
4_L	333_L	1.488	0.85
177_P	284_Q	1.485	0.85
65_A	90_F	1.484	0.84
159_A	163_A	1.480	0.84
19_V	22_H	1.475	0.84
54_F	58_E	1.457	0.83
253_K	314_F	1.447	0.83
206_V	210_F	1.432	0.82
121_S	177_P	1.415	0.81
180_F	184_L	1.408	0.81
310_A	313_L	1.401	0.81
303_A	313_L	1.385	0.80
227_S	233_S	1.383	0.80
361_T	364_L	1.376	0.80
254_V	279_L	1.375	0.80
139_L	172_Y	1.374	0.80
76_L	79_S	1.368	0.79
189_L	194_F	1.351	0.78
180_F	203_G	1.349	0.78
75_A	78_T	1.337	0.78
199_L	202_L	1.336	0.78
95_V	134_Y	1.332	0.77
231_P	234_R	1.331	0.77
241_W	246_C	1.329	0.77
20_H	54_F	1.328	0.77
214_F	222_L	1.320	0.77
248_Y	439_S	1.319	0.77
54_F	57_F	1.313	0.76
228_R	231_P	1.312	0.76
58_E	91_M	1.311	0.76
163_A	202_L	1.310	0.76
129_H	307_C	1.300	0.76
61_L	90_F	1.295	0.75
19_V	54_F	1.292	0.75
306_L	310_A	1.287	0.75
217_F	225_V	1.286	0.75
347_L	446_V	1.283	0.75
22_H	26_I	1.269	0.74
283_A	314_F	1.269	0.74
6_L	93_L	1.264	0.73
206_V	209_T	1.263	0.73
407_G	446_V	1.263	0.73
309_L	326_V	1.261	0.73
435_L	439_S	1.261	0.73
19_V	25_A	1.242	0.72
228_R	234_R	1.237	0.72
160_F	209_T	1.229	0.71
121_S	351_G	1.225	0.71
164_L	209_T	1.225	0.71
20_H	25_A	1.225	0.71
364_L	416_C	1.224	0.71
208_A	428_A	1.210	0.70
238_H	241_W	1.209	0.70
269_P	273_P	1.205	0.70
158_G	203_G	1.204	0.70
175_Y	311_F	1.194	0.69
143_L	430_Y	1.191	0.69
174_Y	178_A	1.188	0.69
94_T	134_Y	1.180	0.68
178_A	291_L	1.180	0.68
228_R	235_G	1.177	0.68
221_Q	224_Q	1.175	0.68
204_L	207_I	1.175	0.68
18_E	82_Y	1.174	0.68
19_V	47_T	1.166	0.67
124_L	136_G	1.164	0.67
39_Y	44_S	1.157	0.67
133_Q	169_K	1.153	0.66
181_V	185_R	1.153	0.66
6_L	9_P	1.152	0.66
214_F	355_L	1.149	0.66
231_P	235_G	1.147	0.66
15_T	22_H	1.133	0.65
15_T	25_A	1.129	0.65
236_L	272_L	1.128	0.65
144_L	148_A	1.124	0.64
18_E	79_S	1.118	0.64
59_W	62_G	1.110	0.63
176_A	202_L	1.102	0.63
288_L	307_C	1.088	0.62
47_T	55_A	1.086	0.62
161_L	203_G	1.085	0.61
146_I	300_F	1.072	0.61
72_E	82_Y	1.069	0.60
432_F	435_L	1.065	0.60
121_S	168_F	1.061	0.60
11_M	54_F	1.060	0.60
25_A	79_S	1.058	0.60
20_H	58_E	1.051	0.59
138_L	408_L	1.048	0.59
438_T	442_C	1.045	0.59
9_P	93_L	1.044	0.58
96_I	125_L	1.040	0.58
126_L	364_L	1.038	0.58
109_L	148_A	1.038	0.58
309_L	323_I	1.034	0.58
72_E	141_L	1.032	0.58
74_V	87_T	1.031	0.58
20_H	43_L	1.030	0.57
285_L	373_L	1.029	0.57
174_Y	280_T	1.029	0.57
39_Y	43_L	1.025	0.57
59_W	68_F	1.013	0.56
210_F	214_F	1.010	0.56
18_E	324_L	1.005	0.56
130_G	362_D	0.999	0.55
57_F	87_T	0.993	0.55
200_I	203_G	0.990	0.54
244_F	254_V	0.987	0.54
45_Y	237_F	0.985	0.54
98_S	444_F	0.979	0.54
408_L	442_C	0.979	0.54
308_S	311_F	0.979	0.54
22_H	25_A	0.978	0.53
23_W	27_T	0.978	0.53
54_F	316_W	0.976	0.53
128_D	132_F	0.973	0.53
33_S	227_S	0.971	0.53
279_L	322_A	0.966	0.53
211_A	373_L	0.966	0.53
131_H	228_R	0.966	0.53
76_L	80_R	0.964	0.52
57_F	61_L	0.963	0.52
112_S	153_R	0.957	0.52
89_L	93_L	0.956	0.52
16_D	27_T	0.951	0.51
129_H	140_G	0.949	0.51
415_H	420_L	0.949	0.51
152_G	297_P	0.948	0.51
135_N	321_K	0.941	0.51
238_H	246_C	0.939	0.50
17_F	84_S	0.938	0.50
58_E	322_A	0.937	0.50
254_V	444_F	0.937	0.50
163_A	210_F	0.934	0.50
4_L	143_L	0.933	0.50
121_S	348_S	0.932	0.50
81_G	137_F	0.929	0.50
97_V	227_S	0.923	0.49
116_L	332_L	0.922	0.49
71_P	74_V	0.919	0.49
136_G	232_F	0.918	0.49
182_Y	291_L	0.917	0.49
228_R	238_H	0.917	0.49
25_A	47_T	0.913	0.48
182_Y	242_A	0.910	0.48
182_Y	303_A	0.910	0.48
150_R	297_P	0.907	0.48
154_D	195_G	0.906	0.48
247_L	251_L	0.906	0.48
143_L	328_L	0.905	0.48
277_F	290_K	0.900	0.47
166_L	180_F	0.900	0.47
149_L	436_M	0.895	0.47
64_V	75_A	0.895	0.47
397_L	421_L	0.895	0.47
5_K	8_L	0.895	0.47
172_Y	177_P	0.893	0.47
291_L	296_T	0.892	0.47
22_H	47_T	0.892	0.47
154_D	182_Y	0.885	0.46
94_T	100_L	0.884	0.46
172_Y	326_V	0.882	0.46
22_H	91_M	0.881	0.46
120_L	296_T	0.880	0.46
272_L	275_L	0.873	0.45
159_A	205_V	0.871	0.45
20_H	47_T	0.871	0.45
29_S	75_A	0.871	0.45
45_Y	81_G	0.868	0.45
43_L	62_G	0.866	0.45
244_F	248_Y	0.865	0.45
56_Y	216_P	0.861	0.45
94_T	277_F	0.860	0.44
239_A	361_T	0.856	0.44
110_F	143_L	0.853	0.44
273_P	276_T	0.852	0.44
370_V	412_L	0.850	0.44
15_T	47_T	0.848	0.44
436_M	440_V	0.843	0.43
174_Y	354_S	0.842	0.43
258_A	431_P	0.841	0.43
120_L	126_L	0.840	0.43
88_K	91_M	0.840	0.43
73_M	84_S	0.839	0.43
2_T	101_L	0.836	0.43
43_L	54_F	0.835	0.43
248_Y	444_F	0.834	0.42
70_D	136_G	0.830	0.42
323_I	340_D	0.828	0.42
168_F	229_L	0.826	0.42
131_H	358_L	0.824	0.42
48_L	55_A	0.820	0.41
131_H	231_P	0.819	0.41
354_S	442_C	0.818	0.41
268_L	271_I	0.817	0.41
57_F	168_F	0.815	0.41
344_F	375_W	0.814	0.41
15_T	54_F	0.810	0.41
376_L	380_L	0.801	0.40
5_K	129_H	0.798	0.40
173_L	230_F	0.798	0.40
322_A	328_L	0.797	0.40
70_D	86_S	0.797	0.40
203_G	206_V	0.795	0.40
185_R	292_W	0.795	0.40
123_G	312_F	0.794	0.40
105_P	416_C	0.793	0.39
131_H	135_N	0.792	0.39
278_L	289_I	0.791	0.39
14_S	19_V	0.790	0.39
90_F	281_L	0.790	0.39
263_T	447_F	0.789	0.39
26_I	436_M	0.788	0.39
281_L	352_H	0.787	0.39
62_G	166_L	0.786	0.39
18_E	71_P	0.785	0.39
210_F	225_V	0.783	0.39
19_V	58_E	0.782	0.39
47_T	238_H	0.780	0.38
126_L	258_A	0.780	0.38
132_F	135_N	0.780	0.38
432_F	439_S	0.778	0.38
331_S	351_G	0.777	0.38
141_L	428_A	0.775	0.38
138_L	175_Y	0.775	0.38
273_P	277_F	0.773	0.38
32_I	418_L	0.772	0.38
144_L	147_A	0.771	0.38
61_L	436_M	0.768	0.38
131_H	235_G	0.767	0.38
8_L	316_W	0.767	0.38
112_S	296_T	0.766	0.37
372_T	375_W	0.766	0.37
414_L	437_L	0.764	0.37
87_T	178_A	0.759	0.37
32_I	417_L	0.759	0.37
33_S	40_Y	0.757	0.37
14_S	20_H	0.756	0.37
159_A	309_L	0.755	0.37
73_M	76_L	0.754	0.37
140_G	178_A	0.753	0.37
412_L	416_C	0.753	0.37
102_L	118_I	0.753	0.37
436_M	439_S	0.751	0.36
111_S	205_V	0.748	0.36
90_F	196_F	0.748	0.36
257_F	264_S	0.747	0.36
106_A	109_L	0.747	0.36
53_L	213_S	0.746	0.36
70_D	221_Q	0.746	0.36
71_P	403_L	0.746	0.36
391_E	406_L	0.745	0.36
127_I	152_G	0.743	0.36
56_Y	87_T	0.742	0.36
404_Y	441_Y	0.742	0.36
162_F	312_F	0.741	0.36
146_I	271_I	0.741	0.36
374_L	378_L	0.741	0.36
100_L	143_L	0.740	0.36
285_L	417_L	0.740	0.36
128_D	131_H	0.740	0.36
34_Q	278_L	0.736	0.35
240_Y	435_L	0.735	0.35
168_F	240_Y	0.734	0.35
387_A	407_G	0.733	0.35
284_Q	308_S	0.729	0.35
300_F	451_L	0.728	0.35
163_A	209_T	0.722	0.34
95_V	166_L	0.721	0.34
321_K	358_L	0.721	0.34
235_G	238_H	0.718	0.34
345_L	375_W	0.714	0.34
132_F	140_G	0.712	0.34
31_P	35_W	0.711	0.34
199_L	430_Y	0.710	0.34
110_F	118_I	0.710	0.34
97_V	108_L	0.709	0.33
81_G	313_L	0.709	0.33
282_L	337_D	0.707	0.33
6_L	208_A	0.707	0.33
34_Q	40_Y	0.706	0.33
313_L	447_F	0.706	0.33
224_Q	434_P	0.705	0.33
177_P	288_L	0.704	0.33
26_I	300_F	0.704	0.33
232_F	333_L	0.703	0.33
249_N	263_T	0.702	0.33
165_L	175_Y	0.702	0.33
348_S	351_G	0.699	0.33
131_H	318_V	0.699	0.33
49_D	55_A	0.698	0.33
31_P	310_A	0.697	0.33
153_R	157_L	0.697	0.33
307_C	311_F	0.695	0.33
404_Y	445_G	0.694	0.32
65_A	87_T	0.694	0.32
347_L	351_G	0.694	0.32
183_L	243_N	0.694	0.32
444_F	448_Y	0.693	0.32
71_P	82_Y	0.689	0.32
185_R	295_P	0.689	0.32
401_E	448_Y	0.689	0.32
207_I	421_L	0.688	0.32
21_R	30_L	0.688	0.32
110_F	281_L	0.688	0.32
152_G	203_G	0.688	0.32
137_F	283_A	0.688	0.32
185_R	432_F	0.687	0.32
224_Q	281_L	0.686	0.32
250_V	440_V	0.685	0.32
318_V	321_K	0.685	0.32
203_G	359_L	0.685	0.32
79_S	82_Y	0.685	0.32
185_R	288_L	0.683	0.32
196_F	212_L	0.683	0.32
346_W	350_V	0.682	0.32
246_C	311_F	0.681	0.32
207_I	418_L	0.679	0.31
308_S	328_L	0.678	0.31
47_T	58_E	0.678	0.31
11_M	43_L	0.677	0.31
105_P	140_G	0.675	0.31
73_M	79_S	0.674	0.31
45_Y	80_R	0.674	0.31
242_A	312_F	0.673	0.31
236_L	242_A	0.672	0.31
236_L	276_T	0.672	0.31
64_V	369_V	0.670	0.31
183_L	187_Y	0.669	0.31
99_D	341_A	0.661	0.30
199_L	207_I	0.660	0.30
81_G	340_D	0.657	0.30
53_L	262_D	0.656	0.30
64_V	90_F	0.656	0.30
132_F	358_L	0.654	0.30
144_L	182_Y	0.654	0.30
115_A	450_W	0.652	0.30
237_F	354_S	0.652	0.30
27_T	318_V	0.651	0.30
142_L	165_L	0.651	0.30
110_F	295_P	0.651	0.30
34_Q	205_V	0.650	0.30
110_F	195_G	0.649	0.29
69_V	116_L	0.646	0.29
312_F	374_L	0.644	0.29
97_V	278_L	0.643	0.29
176_A	205_V	0.642	0.29
214_F	253_K	0.642	0.29
92_R	135_N	0.642	0.29
23_W	49_D	0.641	0.29
116_L	199_L	0.641	0.29
23_W	51_P	0.641	0.29
290_K	306_L	0.640	0.29
167_N	300_F	0.639	0.29
131_H	321_K	0.637	0.29
93_L	97_V	0.637	0.29
53_L	212_L	0.637	0.29
214_F	226_L	0.635	0.29
207_I	452_L	0.634	0.29
385_R	400_L	0.633	0.28
212_L	332_L	0.633	0.28
412_L	443_A	0.633	0.28
57_F	240_Y	0.632	0.28
288_L	292_W	0.631	0.28
311_F	315_G	0.631	0.28
286_P	371_L	0.631	0.28
111_S	412_L	0.631	0.28
18_E	46_W	0.630	0.28
54_F	238_H	0.629	0.28
187_Y	439_S	0.628	0.28
133_Q	320_E	0.627	0.28
131_H	234_R	0.627	0.28
168_F	264_S	0.626	0.28
99_D	263_T	0.625	0.28
400_L	406_L	0.624	0.28
39_Y	47_T	0.624	0.28
29_S	70_D	0.622	0.28
151_Q	443_A	0.622	0.28
32_I	127_I	0.621	0.28
293_R	451_L	0.619	0.28
110_F	302_L	0.619	0.28
149_L	300_F	0.619	0.28
313_L	449_S	0.618	0.28
241_W	315_G	0.618	0.28
442_C	447_F	0.618	0.28
16_D	50_Y	0.618	0.28
20_H	317_H	0.618	0.28
327_L	348_S	0.617	0.27
312_F	319_H	0.617	0.27
95_V	183_L	0.615	0.27
312_F	320_E	0.614	0.27
248_Y	252_D	0.614	0.27
409_I	412_L	0.614	0.27
198_R	326_V	0.612	0.27
125_L	429_R	0.612	0.27
288_L	309_L	0.609	0.27
244_F	253_K	0.609	0.27
386_L	389_K	0.608	0.27
11_M	44_S	0.608	0.27
253_K	263_T	0.607	0.27
303_A	369_V	0.605	0.27
374_L	428_A	0.605	0.27
20_H	57_F	0.605	0.27
220_G	225_V	0.604	0.27
364_L	368_K	0.604	0.27
135_N	169_K	0.604	0.27
173_L	323_I	0.603	0.27
181_V	417_L	0.603	0.27
250_V	436_M	0.603	0.27
143_L	392_S	0.603	0.27
98_S	168_F	0.602	0.27
247_L	440_V	0.601	0.27
95_V	136_G	0.599	0.26
142_L	172_Y	0.598	0.26
68_F	164_L	0.594	0.26
439_S	445_G	0.593	0.26
132_F	228_R	0.593	0.26
168_F	175_Y	0.593	0.26
96_I	421_L	0.593	0.26
80_R	83_E	0.591	0.26
103_Y	176_A	0.591	0.26
112_S	184_L	0.590	0.26
436_M	444_F	0.590	0.26
323_I	351_G	0.587	0.26
132_F	321_K	0.587	0.26
343_A	348_S	0.586	0.26
87_T	90_F	0.585	0.26
305_T	326_V	0.585	0.26
353_F	443_A	0.584	0.26
362_D	444_F	0.584	0.26
177_P	243_N	0.584	0.26
306_L	325_L	0.583	0.25
121_S	352_H	0.582	0.25
4_L	96_I	0.582	0.25
204_L	418_L	0.580	0.25
110_F	332_L	0.580	0.25
312_F	446_V	0.579	0.25
94_T	98_S	0.579	0.25
18_E	80_R	0.578	0.25
2_T	5_K	0.576	0.25
174_Y	311_F	0.575	0.25
83_E	309_L	0.575	0.25
403_L	406_L	0.574	0.25
34_Q	211_A	0.573	0.25
210_F	295_P	0.573	0.25
171_M	246_C	0.572	0.25
47_T	240_Y	0.571	0.25
78_T	81_G	0.571	0.25
49_D	52_P	0.570	0.25
120_L	186_K	0.570	0.25
19_V	43_L	0.568	0.25
25_A	54_F	0.568	0.25
313_L	374_L	0.568	0.25
77_H	269_P	0.567	0.25
25_A	80_R	0.567	0.25
94_T	110_F	0.567	0.25
48_L	51_P	0.567	0.25
177_P	307_C	0.566	0.24
222_L	322_A	0.566	0.24
199_L	363_G	0.565	0.24
195_G	198_R	0.562	0.24
249_N	314_F	0.562	0.24
50_Y	55_A	0.561	0.24
167_N	291_L	0.561	0.24
51_P	55_A	0.559	0.24
252_D	268_L	0.559	0.24
282_L	289_I	0.558	0.24
238_H	315_G	0.557	0.24
193_R	208_A	0.557	0.24
160_F	279_L	0.557	0.24
114_A	285_L	0.554	0.24
79_S	83_E	0.554	0.24
15_T	238_H	0.551	0.24
230_F	236_L	0.550	0.24
135_N	231_P	0.549	0.24
148_A	253_K	0.549	0.24
197_L	211_A	0.548	0.23
241_W	322_A	0.548	0.23
142_L	175_Y	0.548	0.23
135_N	234_R	0.547	0.23
99_D	435_L	0.546	0.23
35_W	55_A	0.545	0.23
60_L	106_A	0.544	0.23
4_L	276_T	0.544	0.23
17_F	248_Y	0.543	0.23
202_L	278_L	0.543	0.23
65_A	434_P	0.542	0.23
111_S	155_L	0.541	0.23
212_L	366_L	0.541	0.23
168_F	182_Y	0.540	0.23
135_N	235_G	0.540	0.23
58_E	88_K	0.540	0.23
185_R	401_E	0.539	0.23
359_L	364_L	0.539	0.23
346_W	404_Y	0.539	0.23
181_V	292_W	0.538	0.23
47_T	239_A	0.538	0.23
270_S	379_S	0.538	0.23
366_L	377_I	0.537	0.23
350_V	411_M	0.536	0.23
253_K	257_F	0.536	0.23
167_N	225_V	0.535	0.23
341_A	379_S	0.532	0.23
20_H	41_E	0.532	0.23
110_F	374_L	0.532	0.23
194_F	418_L	0.531	0.23
46_W	174_Y	0.531	0.23
97_V	289_I	0.531	0.23
46_W	50_Y	0.530	0.22
114_A	155_L	0.529	0.22
188_C	209_T	0.528	0.22
139_L	175_Y	0.528	0.22
92_R	321_K	0.527	0.22
62_G	81_G	0.527	0.22
44_S	47_T	0.527	0.22
178_A	303_A	0.526	0.22
121_S	327_L	0.525	0.22
437_L	440_V	0.525	0.22
122_P	265_F	0.525	0.22
54_F	170_H	0.524	0.22
146_I	149_L	0.524	0.22
20_H	23_W	0.523	0.22
303_A	361_T	0.523	0.22
146_I	333_L	0.523	0.22
4_L	183_L	0.522	0.22
42_D	76_L	0.521	0.22
182_Y	210_F	0.521	0.22
439_S	443_A	0.521	0.22
215_G	334_A	0.520	0.22
110_F	147_A	0.520	0.22
124_L	165_L	0.520	0.22
18_E	65_A	0.518	0.22
82_Y	100_L	0.518	0.22
174_Y	325_L	0.518	0.22
330_L	350_V	0.518	0.22
172_Y	178_A	0.516	0.22
357_P	439_S	0.516	0.22
287_S	362_D	0.516	0.22
351_G	415_H	0.515	0.22
254_V	277_F	0.515	0.22
143_L	276_T	0.514	0.22
86_S	373_L	0.513	0.22
57_F	450_W	0.513	0.22
32_I	450_W	0.511	0.21
305_T	309_L	0.510	0.21
18_E	73_M	0.510	0.21
22_H	43_L	0.509	0.21
107_V	119_L	0.509	0.21
171_M	280_T	0.508	0.21
119_L	127_I	0.508	0.21
94_T	114_A	0.508	0.21
407_G	441_Y	0.507	0.21
167_N	206_V	0.506	0.21
178_A	325_L	0.505	0.21
135_N	318_V	0.505	0.21
171_M	322_A	0.504	0.21
361_T	366_L	0.504	0.21
104_Y	108_L	0.503	0.21
221_Q	378_L	0.503	0.21
159_A	262_D	0.503	0.21
159_A	203_G	0.503	0.21
59_W	125_L	0.503	0.21
230_F	234_R	0.503	0.21
47_T	62_G	0.500	0.21
240_Y	322_A	0.500	0.21
100_L	104_Y	0.500	0.21

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3wajA	1	0.7373	43.9	0.977	Contact Map
2ki9A	1	0.0728	41.5	0.977	Contact Map
4qncA	2	0.1722	3	0.987	Contact Map
1rh5B	1	0.117	2.5	0.987	Contact Map
2ljbA	3	0.0662	2.3	0.988	Contact Map
3rjaA	1	0.1678	2.2	0.988	Contact Map
3ahqA	1	0.1258	1.5	0.989	Contact Map
2dawA	1	0.1634	1.4	0.989	Contact Map
1tc1A	2	0.1038	1.4	0.989	Contact Map
1spfA	1	0.0773	1.2	0.989	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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