Mlo - PFAM28P - GREMLIN Contacts

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Mlo - Mlo family

PFAM:	PF03094	Sequences: ERSLEETPTWAVAVVCFVIVLISLLIERLLHRLGKWLKKKHKKALFEALEKIKEELMLLGFISLLLTVGQGPISKICIPESVASTMLPCKKEEEEKEEEEEHRRRLLSFSDSGSGRRLLAAGGSDYCAKKGKVPLLSLEGLHQLHIFIFVLAVFHVLYSVLTMALGRAKIRRWKAWEDETKTLEYQFSNDPERFRFTRQTSFVRRHLGFWSKSPILLWIVCFFRQFYGSVTKSDYLTLRHGFIMAHLAPNSKFDFHKYIKRSLEDDFKVVVGISPYLWFFVVIFLLLNVHGWHTYFWLSFIPLILLLLVGTKLQHIITKLALEIAERHAVVKGAPVVQPSDDLFWFGRPRLVLFLIHFILFQNAFELAFFFWIWYEFGFKSCFHENVELIIIRLVLGVIVQFLCSYSTLPLYALVTQMGSSMKKAIFDEQVAKALKGWHKKAKKKKKHGKSSSSSTPSSSRPTTPSHGSSPVHLLHNYK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_10
Length:	479 (463)
Sequences:	636 (386)
Seq/√Len:	18.0
META:	0.009

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
116_R	119_L	5.915	1.00
116_R	120_A	5.830	1.00
104_R	107_L	4.180	1.00
34_G	46_F	3.799	1.00
387_V	391_I	3.605	1.00
117_R	120_A	3.447	1.00
158_Y	221_C	3.083	0.99
78_I	82_V	2.926	0.99
142_H	145_H	2.847	0.98
142_H	146_I	2.774	0.98
22_I	69_G	2.640	0.97
170_I	233_S	2.633	0.97
147_F	393_R	2.627	0.97
280_F	358_F	2.611	0.97
459_S	462_P	2.608	0.97
393_R	401_Q	2.600	0.97
31_H	61_F	2.597	0.97
69_G	199_Q	2.484	0.96
103_R	107_L	2.368	0.95
289_V	299_S	2.327	0.94
38_K	46_F	2.301	0.94
203_V	207_L	2.241	0.93
136_L	140_G	2.239	0.93
317_I	401_Q	2.207	0.93
147_F	339_P	2.198	0.92
42_K	167_R	2.180	0.92
83_A	228_G	2.163	0.92
67_T	374_W	2.144	0.91
139_E	358_F	2.142	0.91
103_R	108_S	2.133	0.91
376_E	393_R	2.114	0.91
458_S	464_T	2.107	0.91
55_E	145_H	2.100	0.91
78_I	85_T	2.057	0.90
172_R	282_V	2.056	0.90
265_D	308_L	2.013	0.89
381_S	393_R	2.008	0.88
75_K	126_Y	2.006	0.88
311_T	386_N	1.986	0.88
201_S	206_H	1.982	0.88
366_E	393_R	1.976	0.88
305_L	359_I	1.948	0.87
187_F	366_E	1.905	0.86
118_L	121_A	1.899	0.85
105_R	108_S	1.892	0.85
34_G	264_E	1.884	0.85
219_I	223_F	1.855	0.84
281_V	405_S	1.832	0.83
106_L	118_L	1.823	0.83
299_S	422_M	1.819	0.83
79_P	303_L	1.804	0.82
362_Q	374_W	1.779	0.81
460_S	464_T	1.760	0.81
299_S	389_L	1.738	0.80
317_I	442_A	1.712	0.79
56_L	149_F	1.708	0.78
143_Q	165_L	1.697	0.78
461_R	464_T	1.688	0.78
144_L	267_F	1.677	0.77
317_I	393_R	1.673	0.77
78_I	265_D	1.672	0.77
400_V	409_L	1.649	0.76
30_L	447_K	1.649	0.76
33_L	338_Q	1.645	0.76
127_C	130_K	1.635	0.75
166_G	263_L	1.630	0.75
17_F	78_I	1.629	0.75
131_G	402_F	1.628	0.75
426_I	435_L	1.627	0.75
70_Q	148_I	1.627	0.75
161_L	376_E	1.626	0.75
280_F	374_W	1.602	0.74
425_A	428_D	1.596	0.73
79_P	82_V	1.589	0.73
298_L	380_K	1.586	0.73
376_E	401_Q	1.585	0.73
166_G	409_L	1.584	0.73
159_S	445_K	1.572	0.72
83_A	159_S	1.572	0.72
218_W	339_P	1.571	0.72
70_Q	263_L	1.568	0.72
18_V	206_H	1.556	0.72
443_K	447_K	1.552	0.71
158_Y	343_L	1.548	0.71
104_R	118_L	1.531	0.70
55_E	65_L	1.517	0.70
190_D	193_R	1.516	0.69
425_A	443_K	1.500	0.69
103_R	106_L	1.490	0.68
291_G	296_F	1.489	0.68
62_I	314_Q	1.489	0.68
40_K	340_S	1.480	0.68
179_E	232_K	1.480	0.68
246_H	274_S	1.477	0.67
221_C	416_T	1.476	0.67
170_I	245_A	1.470	0.67
26_I	190_D	1.464	0.67
86_M	367_L	1.458	0.66
74_S	338_Q	1.452	0.66
160_V	279_F	1.452	0.66
97_E	120_A	1.451	0.66
195_R	335_P	1.450	0.66
12_V	427_F	1.446	0.66
29_L	90_K	1.432	0.65
46_F	301_I	1.429	0.65
193_R	330_V	1.425	0.65
418_M	423_K	1.423	0.64
365_F	372_W	1.421	0.64
284_F	288_N	1.406	0.63
150_V	339_P	1.396	0.63
459_S	463_T	1.390	0.63
86_M	139_E	1.389	0.62
324_I	335_P	1.385	0.62
5_E	368_A	1.382	0.62
17_F	21_L	1.378	0.62
66_L	166_G	1.377	0.62
156_V	264_E	1.372	0.61
282_V	373_I	1.364	0.61
11_A	200_T	1.364	0.61
370_F	384_H	1.352	0.60
156_V	373_I	1.350	0.60
159_S	279_F	1.347	0.60
147_F	319_K	1.344	0.60
193_R	200_T	1.335	0.59
109_F	112_S	1.331	0.59
181_K	186_Q	1.327	0.59
37_L	394_L	1.326	0.59
289_V	321_A	1.326	0.59
348_R	424_K	1.325	0.59
173_W	176_W	1.321	0.58
180_T	366_E	1.319	0.58
250_N	314_Q	1.316	0.58
25_L	107_L	1.315	0.58
149_F	361_F	1.302	0.57
247_L	320_L	1.294	0.57
215_I	322_L	1.282	0.56
40_K	136_L	1.282	0.56
27_E	31_H	1.279	0.56
228_G	231_T	1.278	0.56
150_V	218_W	1.265	0.55
88_P	307_L	1.261	0.55
379_F	387_V	1.260	0.55
246_H	361_F	1.257	0.55
59_L	358_F	1.256	0.55
171_R	256_H	1.248	0.54
449_G	455_S	1.242	0.54
153_V	391_I	1.240	0.54
301_I	342_D	1.236	0.53
237_T	425_A	1.234	0.53
147_F	317_I	1.222	0.52
3_S	338_Q	1.221	0.52
287_L	374_W	1.218	0.52
118_L	394_L	1.217	0.52
37_L	238_L	1.214	0.52
279_F	414_L	1.213	0.52
286_L	292_W	1.210	0.52
159_S	364_A	1.207	0.52
155_H	435_L	1.206	0.51
457_P	460_S	1.205	0.51
311_T	326_E	1.189	0.50
150_V	368_A	1.188	0.50
15_V	78_I	1.184	0.50
180_T	185_Y	1.182	0.50
74_S	238_L	1.175	0.50
371_F	374_W	1.174	0.50
435_L	438_W	1.168	0.49
138_L	283_I	1.168	0.49
427_F	438_W	1.162	0.49
425_A	445_K	1.159	0.49
165_L	376_E	1.154	0.48
4_L	13_A	1.151	0.48
6_E	90_K	1.148	0.48
198_R	201_S	1.148	0.48
414_L	431_V	1.143	0.48
190_D	194_F	1.142	0.48
245_A	332_K	1.142	0.48
106_L	121_A	1.140	0.47
3_S	464_T	1.140	0.47
139_E	238_L	1.137	0.47
55_E	142_H	1.136	0.47
15_V	56_L	1.136	0.47
337_V	390_I	1.133	0.47
330_V	333_G	1.132	0.47
157_L	183_L	1.132	0.47
209_F	316_I	1.118	0.46
220_V	317_I	1.117	0.46
14_V	228_G	1.107	0.45
458_S	463_T	1.102	0.45
287_L	294_T	1.102	0.45
343_L	373_I	1.102	0.45
412_Y	415_V	1.098	0.45
442_A	445_K	1.097	0.45
101_E	130_K	1.096	0.45
423_K	445_K	1.094	0.45
9_T	12_V	1.093	0.45
281_V	401_Q	1.091	0.44
55_E	133_V	1.089	0.44
75_K	443_K	1.089	0.44
52_I	402_F	1.088	0.44
175_A	232_K	1.086	0.44
218_W	368_A	1.085	0.44
76_I	425_A	1.083	0.44
3_S	30_L	1.082	0.44
166_G	266_D	1.078	0.44
37_L	431_V	1.077	0.44
180_T	205_R	1.076	0.44
198_R	217_L	1.074	0.43
30_L	323_E	1.073	0.43
165_L	375_Y	1.071	0.43
147_F	286_L	1.070	0.43
16_C	27_E	1.068	0.43
18_V	53_K	1.065	0.43
104_R	114_S	1.062	0.43
100_E	301_I	1.061	0.43
78_I	435_L	1.055	0.42
425_A	435_L	1.054	0.42
76_I	238_L	1.053	0.42
33_L	165_L	1.049	0.42
410_P	417_Q	1.046	0.42
316_I	403_L	1.043	0.42
59_L	292_W	1.041	0.41
105_R	118_L	1.038	0.41
422_M	435_L	1.036	0.41
52_I	161_L	1.033	0.41
76_I	229_S	1.032	0.41
351_L	445_K	1.030	0.41
305_L	324_I	1.027	0.41
161_L	425_A	1.026	0.41
59_L	66_L	1.023	0.40
163_M	378_G	1.021	0.40
197_T	330_V	1.019	0.40
152_A	434_A	1.016	0.40
135_L	232_K	1.016	0.40
3_S	139_E	1.016	0.40
237_T	270_V	1.013	0.40
157_L	352_V	1.010	0.40
215_I	237_T	1.008	0.39
86_M	294_T	1.001	0.39
47_E	67_T	1.001	0.39
196_F	200_T	1.000	0.39
295_Y	300_F	0.999	0.39
136_L	288_N	0.998	0.39
99_E	102_H	0.997	0.39
299_S	321_A	0.996	0.39
386_N	394_L	0.995	0.39
81_S	208_G	0.992	0.39
170_I	205_R	0.991	0.38
58_L	359_I	0.989	0.38
262_S	269_V	0.986	0.38
304_I	316_I	0.986	0.38
240_H	316_I	0.985	0.38
147_F	401_Q	0.977	0.38
295_Y	366_E	0.976	0.38
25_L	29_L	0.973	0.37
171_R	337_V	0.967	0.37
156_V	338_Q	0.961	0.37
182_T	221_C	0.958	0.37
73_I	132_K	0.957	0.37
30_L	340_S	0.955	0.36
267_F	271_V	0.954	0.36
351_L	444_K	0.953	0.36
22_I	65_L	0.950	0.36
165_L	399_I	0.950	0.36
270_V	290_H	0.950	0.36
99_E	395_V	0.948	0.36
395_V	416_T	0.948	0.36
78_I	130_K	0.947	0.36
116_R	121_A	0.946	0.36
147_F	158_Y	0.946	0.36
289_V	371_F	0.945	0.36
8_P	381_S	0.941	0.36
241_G	420_S	0.941	0.36
74_S	315_H	0.941	0.36
14_V	386_N	0.940	0.36
209_F	304_I	0.938	0.35
78_I	230_V	0.937	0.35
35_K	339_P	0.937	0.35
259_I	414_L	0.933	0.35
169_K	435_L	0.932	0.35
273_I	393_R	0.932	0.35
193_R	232_K	0.929	0.35
456_T	461_R	0.929	0.35
17_F	265_D	0.928	0.35
88_P	412_Y	0.928	0.35
340_S	343_L	0.928	0.35
383_F	389_L	0.925	0.35
106_L	111_D	0.925	0.35
262_S	413_A	0.924	0.35
91_K	265_D	0.923	0.35
326_E	426_I	0.923	0.35
75_K	161_L	0.922	0.35
22_I	285_L	0.922	0.35
448_H	451_S	0.921	0.35
179_E	194_F	0.920	0.34
11_A	224_R	0.916	0.34
10_W	15_V	0.916	0.34
376_E	402_F	0.916	0.34
12_V	49_L	0.913	0.34
282_V	288_N	0.912	0.34
320_L	325_A	0.907	0.34
147_F	231_T	0.906	0.34
436_K	439_H	0.903	0.34
171_R	227_Y	0.902	0.33
367_L	371_F	0.898	0.33
335_P	434_A	0.897	0.33
158_Y	392_I	0.895	0.33
277_L	299_S	0.891	0.33
103_R	109_F	0.891	0.33
206_H	364_A	0.890	0.33
314_Q	341_D	0.888	0.33
409_L	413_A	0.885	0.33
141_L	145_H	0.882	0.32
260_K	269_V	0.881	0.32
264_E	301_I	0.880	0.32
164_A	380_K	0.880	0.32
305_L	398_V	0.879	0.32
82_V	452_S	0.874	0.32
78_I	269_V	0.873	0.32
422_M	427_F	0.872	0.32
425_A	446_K	0.872	0.32
28_R	58_L	0.871	0.32
28_R	68_V	0.871	0.32
3_S	74_S	0.866	0.32
217_L	315_H	0.866	0.32
130_K	367_L	0.865	0.31
153_V	364_A	0.865	0.31
24_L	27_E	0.864	0.31
31_H	67_T	0.863	0.31
15_V	27_E	0.861	0.31
104_R	108_S	0.861	0.31
339_P	401_Q	0.858	0.31
299_S	366_E	0.856	0.31
259_I	320_L	0.850	0.31
115_G	119_L	0.849	0.31
459_S	464_T	0.847	0.31
260_K	305_L	0.846	0.30
319_K	352_V	0.845	0.30
45_L	53_K	0.845	0.30
311_T	331_V	0.845	0.30
2_R	206_H	0.842	0.30
306_L	376_E	0.842	0.30
54_E	296_F	0.842	0.30
410_P	414_L	0.842	0.30
158_Y	306_L	0.840	0.30
449_G	452_S	0.840	0.30
134_P	326_E	0.838	0.30
321_A	364_A	0.835	0.30
23_S	62_I	0.834	0.30
367_L	409_L	0.833	0.30
94_E	398_V	0.832	0.30
68_V	368_A	0.826	0.29
207_L	210_W	0.826	0.29
389_L	395_V	0.824	0.29
149_F	246_H	0.823	0.29
374_W	399_I	0.822	0.29
80_E	301_I	0.818	0.29
390_I	402_F	0.818	0.29
169_K	396_L	0.818	0.29
457_P	462_P	0.817	0.29
67_T	271_V	0.817	0.29
155_H	362_Q	0.816	0.29
357_H	361_F	0.816	0.29
200_T	206_H	0.815	0.29
32_R	54_E	0.814	0.29
195_R	200_T	0.814	0.29
258_Y	264_E	0.813	0.29
43_K	311_T	0.809	0.29
165_L	200_T	0.805	0.28
410_P	415_V	0.805	0.28
114_S	118_L	0.804	0.28
226_F	229_S	0.800	0.28
151_L	257_K	0.799	0.28
265_D	425_A	0.799	0.28
358_F	374_W	0.799	0.28
224_R	439_H	0.799	0.28
248_A	320_L	0.797	0.28
358_F	403_L	0.795	0.28
414_L	417_Q	0.791	0.28
419_G	427_F	0.791	0.28
26_I	83_A	0.790	0.28
34_G	142_H	0.789	0.28
85_T	407_S	0.789	0.28
252_K	426_I	0.788	0.28
157_L	402_F	0.787	0.27
26_I	316_I	0.785	0.27
62_I	142_H	0.785	0.27
30_L	131_G	0.784	0.27
308_L	362_Q	0.784	0.27
216_L	351_L	0.783	0.27
125_D	153_V	0.782	0.27
12_V	16_C	0.782	0.27
179_E	206_H	0.782	0.27
446_K	449_G	0.780	0.27
96_K	283_I	0.779	0.27
10_W	16_C	0.778	0.27
330_V	336_V	0.778	0.27
339_P	393_R	0.777	0.27
136_L	227_Y	0.773	0.27
185_Y	193_R	0.773	0.27
3_S	342_D	0.773	0.27
213_S	431_V	0.771	0.27
71_G	139_E	0.768	0.27
85_T	179_E	0.767	0.27
87_L	373_I	0.765	0.26
25_L	392_I	0.764	0.26
13_A	58_L	0.762	0.26
221_C	322_L	0.761	0.26
206_H	216_L	0.758	0.26
237_T	336_V	0.758	0.26
259_I	315_H	0.756	0.26
165_L	303_L	0.755	0.26
314_Q	319_K	0.752	0.26
427_F	434_A	0.751	0.26
4_L	12_V	0.751	0.26
104_R	113_G	0.750	0.26
201_S	217_L	0.750	0.26
62_I	147_F	0.750	0.26
80_E	84_S	0.750	0.26
323_E	397_G	0.748	0.26
9_T	13_A	0.748	0.26
342_D	350_R	0.745	0.25
39_K	319_K	0.745	0.25
452_S	455_S	0.744	0.25
301_I	362_Q	0.743	0.25
246_H	258_Y	0.741	0.25
358_F	378_G	0.739	0.25
87_L	135_L	0.739	0.25
153_V	316_I	0.739	0.25
421_S	442_A	0.738	0.25
309_V	385_E	0.736	0.25
82_V	130_K	0.734	0.25
281_V	298_L	0.731	0.25
110_S	115_G	0.731	0.25
254_D	270_V	0.731	0.25
58_L	149_F	0.728	0.25
24_L	34_G	0.728	0.25
129_K	283_I	0.725	0.25
171_R	263_L	0.724	0.25
75_K	215_I	0.723	0.24
414_L	420_S	0.721	0.24
145_H	361_F	0.721	0.24
185_Y	366_E	0.716	0.24
421_S	433_K	0.716	0.24
206_H	414_L	0.716	0.24
383_F	397_G	0.712	0.24
418_M	438_W	0.710	0.24
28_R	32_R	0.710	0.24
135_L	174_K	0.709	0.24
163_M	358_F	0.708	0.24
58_L	361_F	0.707	0.24
170_I	184_E	0.707	0.24
250_N	256_H	0.707	0.24
133_V	331_V	0.706	0.24
99_E	120_A	0.704	0.24
143_Q	200_T	0.703	0.24
342_D	430_Q	0.702	0.24
8_P	267_F	0.701	0.23
32_R	354_F	0.700	0.23
161_L	165_L	0.698	0.23
36_W	143_Q	0.697	0.23
12_V	264_E	0.695	0.23
11_A	50_E	0.695	0.23
30_L	307_L	0.693	0.23
71_G	265_D	0.691	0.23
359_I	431_V	0.691	0.23
143_Q	217_L	0.690	0.23
96_K	108_S	0.690	0.23
207_L	254_D	0.688	0.23
86_M	358_F	0.688	0.23
36_W	50_E	0.686	0.23
289_V	445_K	0.685	0.23
137_S	147_F	0.685	0.23
17_F	394_L	0.685	0.23
288_N	383_F	0.683	0.23
343_L	393_R	0.683	0.23
145_H	364_A	0.682	0.23
87_L	357_H	0.681	0.23
54_E	384_H	0.681	0.23
186_Q	254_D	0.679	0.23
250_N	334_A	0.678	0.22
73_I	454_S	0.677	0.22
317_I	339_P	0.677	0.22
20_V	366_E	0.677	0.22
225_Q	229_S	0.677	0.22
56_L	246_H	0.675	0.22
179_E	190_D	0.675	0.22
175_A	347_G	0.675	0.22
199_Q	232_K	0.674	0.22
400_V	420_S	0.673	0.22
308_L	328_H	0.672	0.22
7_T	16_C	0.672	0.22
165_L	353_L	0.670	0.22
241_G	282_V	0.669	0.22
143_Q	191_P	0.666	0.22
174_K	377_F	0.665	0.22
180_T	200_T	0.662	0.22
254_D	352_V	0.661	0.22
307_L	409_L	0.660	0.22
273_I	401_Q	0.660	0.22
65_L	69_G	0.659	0.22
37_L	291_G	0.659	0.22
184_E	358_F	0.658	0.22
298_L	393_R	0.657	0.22
443_K	458_S	0.656	0.22
408_T	416_T	0.656	0.22
115_G	118_L	0.655	0.22
306_L	314_Q	0.654	0.21
139_E	369_F	0.653	0.21
23_S	31_H	0.652	0.21
311_T	429_E	0.652	0.21
57_M	63_S	0.652	0.21
236_L	379_F	0.651	0.21
45_L	238_L	0.649	0.21
210_W	220_V	0.647	0.21
174_K	253_F	0.646	0.21
262_S	425_A	0.646	0.21
374_W	384_H	0.646	0.21
94_E	102_H	0.645	0.21
174_K	338_Q	0.644	0.21
19_I	352_V	0.644	0.21
86_M	373_I	0.644	0.21
158_Y	237_T	0.643	0.21
230_V	357_H	0.643	0.21
177_E	261_R	0.642	0.21
39_K	358_F	0.640	0.21
245_A	348_R	0.640	0.21
147_F	343_L	0.640	0.21
283_I	289_V	0.639	0.21
219_I	335_P	0.638	0.21
5_E	10_W	0.637	0.21
71_G	116_R	0.636	0.21
81_S	431_V	0.635	0.21
78_I	456_T	0.634	0.21
219_I	371_F	0.633	0.21
275_P	286_L	0.633	0.21
238_L	319_K	0.632	0.21
59_L	62_I	0.632	0.21
203_V	277_L	0.631	0.21
82_V	398_V	0.631	0.21
101_E	106_L	0.630	0.20
82_V	273_I	0.628	0.20
223_F	447_K	0.627	0.20
280_F	362_Q	0.626	0.20
214_P	221_C	0.625	0.20
230_V	263_L	0.624	0.20
300_F	445_K	0.624	0.20
282_V	338_Q	0.623	0.20
424_K	434_A	0.623	0.20
139_E	287_L	0.622	0.20
113_G	254_D	0.621	0.20
22_I	62_I	0.620	0.20
218_W	315_H	0.619	0.20
65_L	169_K	0.618	0.20
143_Q	423_K	0.616	0.20
183_L	371_F	0.615	0.20
30_L	49_L	0.614	0.20
21_L	342_D	0.611	0.20
216_L	393_R	0.611	0.20
71_G	215_I	0.610	0.20
47_E	268_K	0.607	0.20
396_L	413_A	0.605	0.20
78_I	254_D	0.603	0.19
356_I	359_I	0.603	0.19
18_V	285_L	0.602	0.19
306_L	400_V	0.601	0.19
218_W	314_Q	0.601	0.19
286_L	357_H	0.601	0.19
410_P	413_A	0.600	0.19
68_V	150_V	0.600	0.19
60_G	63_S	0.598	0.19
124_S	134_P	0.598	0.19
428_D	447_K	0.596	0.19
299_S	386_N	0.595	0.19
327_R	331_V	0.594	0.19
107_L	110_S	0.593	0.19
29_L	414_L	0.592	0.19
23_S	27_E	0.592	0.19
5_E	396_L	0.592	0.19
21_L	136_L	0.592	0.19
272_G	362_Q	0.591	0.19
14_V	364_A	0.591	0.19
219_I	299_S	0.591	0.19
216_L	347_G	0.590	0.19
401_Q	405_S	0.590	0.19
272_G	357_H	0.590	0.19
230_V	416_T	0.589	0.19
19_I	138_L	0.588	0.19
161_L	435_L	0.587	0.19
369_F	393_R	0.586	0.19
348_R	386_N	0.586	0.19
145_H	149_F	0.586	0.19
155_H	354_F	0.586	0.19
28_R	368_A	0.585	0.19
198_R	340_S	0.584	0.19
105_R	316_I	0.584	0.19
33_L	314_Q	0.582	0.19
460_S	463_T	0.581	0.19
79_P	126_Y	0.580	0.19
286_L	373_I	0.579	0.19
163_M	375_Y	0.578	0.18
334_A	368_A	0.577	0.18
299_S	371_F	0.577	0.18
24_L	182_T	0.577	0.18
339_P	368_A	0.576	0.18
311_T	416_T	0.575	0.18
34_G	49_L	0.574	0.18
14_V	445_K	0.573	0.18
101_E	104_R	0.571	0.18
17_F	159_S	0.571	0.18
240_H	333_G	0.571	0.18
56_L	361_F	0.571	0.18
202_F	246_H	0.570	0.18
276_Y	426_I	0.568	0.18
60_G	77_C	0.565	0.18
256_H	336_V	0.562	0.18
178_D	267_F	0.562	0.18
70_Q	142_H	0.562	0.18
414_L	434_A	0.561	0.18
328_H	331_V	0.559	0.18
404_C	408_T	0.559	0.18
105_R	115_G	0.559	0.18
188_S	288_N	0.557	0.18
67_T	267_F	0.557	0.18
82_V	254_D	0.557	0.18
86_M	138_L	0.556	0.18
323_E	424_K	0.554	0.18
143_Q	377_F	0.553	0.18
150_V	295_Y	0.552	0.18
58_L	320_L	0.551	0.18
213_S	400_V	0.551	0.18
386_N	402_F	0.549	0.17
296_F	299_S	0.549	0.17
243_I	420_S	0.548	0.17
110_S	117_R	0.547	0.17
71_G	358_F	0.547	0.17
33_L	78_I	0.545	0.17
18_V	301_I	0.545	0.17
196_F	416_T	0.545	0.17
171_R	253_F	0.544	0.17
142_H	361_F	0.544	0.17
133_V	369_F	0.542	0.17
199_Q	328_H	0.542	0.17
374_W	379_F	0.541	0.17
6_E	26_I	0.541	0.17
108_S	115_G	0.540	0.17
86_M	167_R	0.540	0.17
189_N	193_R	0.538	0.17
428_D	432_A	0.538	0.17
260_K	320_L	0.537	0.17
456_T	460_S	0.537	0.17
73_I	91_K	0.537	0.17
424_K	448_H	0.535	0.17
281_V	339_P	0.535	0.17
281_V	317_I	0.534	0.17
323_E	340_S	0.534	0.17
135_L	340_S	0.533	0.17
218_W	295_Y	0.533	0.17
154_F	159_S	0.533	0.17
78_I	83_A	0.532	0.17
218_W	334_A	0.532	0.17
98_E	169_K	0.531	0.17
55_E	362_Q	0.530	0.17
456_T	462_P	0.530	0.17
145_H	405_S	0.528	0.17
348_R	448_H	0.527	0.17
281_V	357_H	0.527	0.17
180_T	206_H	0.526	0.17
30_L	41_H	0.525	0.17
67_T	360_L	0.525	0.17
406_Y	413_A	0.525	0.17
312_K	316_I	0.525	0.17
220_V	414_L	0.523	0.17
197_T	335_P	0.519	0.16
161_L	400_V	0.519	0.16
215_I	318_T	0.518	0.16
318_T	409_L	0.514	0.16
125_D	314_Q	0.513	0.16
41_H	105_R	0.512	0.16
408_T	412_Y	0.512	0.16
108_S	124_S	0.512	0.16
136_L	306_L	0.511	0.16
284_F	287_L	0.511	0.16
103_R	113_G	0.510	0.16
16_C	263_L	0.510	0.16
56_L	202_F	0.508	0.16
117_R	121_A	0.508	0.16
183_L	351_L	0.507	0.16
300_F	392_I	0.507	0.16
275_P	282_V	0.506	0.16
224_R	314_Q	0.505	0.16
155_H	210_W	0.503	0.16
347_G	452_S	0.503	0.16
33_L	163_M	0.500	0.16
96_K	311_T	0.500	0.16

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2m3eA	1	0.0939	46.1	0.984	Contact Map
2kncA	1	0.1023	22.7	0.987	Contact Map
2k1aA	1	0.0814	14	0.988	Contact Map
4k0jA	3	0.1879	13.7	0.988	Contact Map
4b19A	1	0.0626	13.6	0.988	Contact Map
2l8sA	1	0.0898	10.1	0.989	Contact Map
3alzB	1	0.1378	9.8	0.989	Contact Map
4mt1A	3	0.2025	7.1	0.989	Contact Map
1vqsA	6	0.2213	7.1	0.989	Contact Map
3aqpA	1	0.1712	5.6	0.99	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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