GREMLIN Database
Transposase_24 - Plant transposase (Ptta/En/Spm family)
PFAM: PF03004 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 141 (129)
Sequences: 735 (583)
Seq/√Len: 51.3
META: 0.004

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
41_K49_E6.2311.00
24_N27_N3.6141.00
81_E85_E3.2731.00
14_S17_F3.1991.00
56_R62_E2.9321.00
8_L12_W2.7161.00
50_M53_E2.4811.00
75_F84_I2.2821.00
133_R138_G2.1711.00
120_F124_L2.1431.00
15_P18_K2.0231.00
12_W17_F1.9951.00
19_K23_K1.9771.00
38_S46_V1.9310.99
53_E66_K1.9070.99
86_K89_E1.8850.99
48_E51_E1.7510.99
20_K24_N1.7090.99
36_H39_G1.7000.99
44_A47_R1.6530.98
68_H134_G1.6430.98
51_E58_P1.6210.98
50_M66_K1.5570.97
14_S21_S1.5210.97
23_K27_N1.4920.97
38_S67_T1.4840.97
41_K46_V1.4800.97
59_S62_E1.4320.96
15_P19_K1.4190.96
46_V67_T1.4130.96
96_S99_S1.4010.95
43_F46_V1.3820.95
5_W9_V1.3500.94
125_G129_K1.3340.94
50_M54_L1.3300.94
65_K69_T1.3180.93
19_K26_A1.2870.93
3_D19_K1.2850.93
84_I87_L1.2730.92
35_K77_D1.2330.91
124_L127_E1.2070.90
22_E26_A1.2030.90
25_K70_K1.1630.88
39_G42_S1.1600.88
117_N120_F1.1520.88
93_E97_Q1.1490.88
96_S100_S1.1460.88
9_V13_N1.1440.87
70_K74_T1.1420.87
116_E119_I1.1280.87
37_T68_H1.1250.87
87_L91_V1.1240.86
61_L65_K1.0820.84
30_G33_K1.0760.84
10_A22_E1.0620.83
56_R59_S1.0490.82
38_S43_F1.0420.82
21_S32_G1.0290.81
90_L93_E1.0270.81
7_E13_N1.0190.81
124_L129_K1.0160.80
3_D6_E1.0150.80
4_Q9_V1.0040.80
77_D80_A0.9750.77
85_E88_E0.9740.77
4_Q17_F0.9510.76
2_P6_E0.9510.76
96_S104_S0.9510.76
94_R97_Q0.9380.75
132_V138_G0.9270.74
25_K30_G0.9060.72
73_G85_E0.8990.72
83_I87_L0.8870.70
65_K88_E0.8860.70
15_P22_E0.8820.70
125_G132_V0.8810.70
68_H88_E0.8730.69
82_E86_K0.8630.68
41_K45_R0.8610.68
129_K133_R0.8610.68
7_E11_Y0.8550.68
72_D76_V0.8410.66
28_R36_H0.8370.66
58_P64_F0.8330.66
26_A30_G0.8280.65
9_V15_P0.8270.65
40_S43_F0.8270.65
133_R139_V0.8250.65
8_L25_K0.8200.64
118_D121_L0.8080.63
55_G66_K0.8070.63
66_K69_T0.8050.63
12_W42_S0.8030.63
92_E96_S0.7990.62
5_W40_S0.7980.62
132_V136_G0.7970.62
19_K22_E0.7950.62
23_K33_K0.7920.62
6_E15_P0.7900.61
16_K19_K0.7880.61
18_K22_E0.7840.61
17_F21_S0.7830.61
92_E97_Q0.7810.61
118_D122_E0.7670.59
76_V80_A0.7640.59
124_L132_V0.7640.59
58_P67_T0.7600.58
16_K22_E0.7560.58
51_E56_R0.7550.58
78_E81_E0.7540.58
21_S25_K0.7330.56
12_W27_N0.7300.55
100_S105_E0.7220.55
30_G77_D0.7220.55
15_P20_K0.7210.55
95_E102_S0.7190.54
25_K125_G0.7140.54
11_Y17_F0.7060.53
8_L11_Y0.7050.53
132_V139_V0.7030.53
26_A79_K0.7030.53
24_N39_G0.7030.53
32_G138_G0.7000.52
20_K139_V0.6940.52
44_A56_R0.6910.51
89_E94_R0.6900.51
47_R131_R0.6860.51
4_Q24_N0.6840.51
3_D69_T0.6780.50
90_L95_E0.6750.50
84_I90_L0.6750.50
115_E118_D0.6700.49
56_R61_L0.6670.49
18_K25_K0.6660.49
124_L138_G0.6620.48
88_E97_Q0.6600.48
5_W37_T0.6590.48
13_N17_F0.6580.48
21_S39_G0.6540.48
35_K46_V0.6480.47
98_L101_D0.6470.47
40_S46_V0.6380.46
18_K24_N0.6370.46
51_E54_L0.6320.45
3_D13_N0.6300.45
94_R101_D0.6300.45
3_D16_K0.6300.45
72_D80_A0.6280.45
127_E133_R0.6220.44
66_K80_A0.6170.44
99_S104_S0.6160.44
2_P22_E0.6140.43
33_K38_S0.6140.43
35_K40_S0.6130.43
4_Q8_L0.6120.43
19_K66_K0.6110.43
32_G35_K0.6090.43
23_K69_T0.6020.42
88_E96_S0.5990.42
56_R76_V0.5990.42
52_K69_T0.5950.42
34_H38_S0.5930.41
5_W68_H0.5890.41
37_T83_I0.5880.41
17_F24_N0.5850.41
35_K42_S0.5790.40
21_S24_N0.5750.40
53_E75_F0.5660.39
5_W134_G0.5640.38
20_K62_E0.5620.38
87_L95_E0.5580.38
34_H43_F0.5530.37
118_D123_V0.5530.37
24_N42_S0.5470.37
100_S103_S0.5470.37
17_F127_E0.5460.37
40_S125_G0.5430.36
88_E92_E0.5420.36
28_R55_G0.5380.36
89_E92_E0.5320.35
11_Y67_T0.5290.35
125_G128_K0.5270.35
25_K33_K0.5270.35
129_K135_L0.5240.35
39_G43_F0.5100.33
91_V98_L0.5070.33
92_E103_S0.5070.33
10_A58_P0.5060.33
85_E92_E0.5040.33
98_L103_S0.5030.33
70_K80_A0.5020.33
10_A13_N0.5000.32
14_S25_K0.5000.32
40_S45_R0.5000.32
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3j7aY 1 0.6241 13.7 0.922 Contact Map
4w23T 1 0.617 7.7 0.931 Contact Map
3j60T 1 0.6099 6.2 0.934 Contact Map
4bpeT 1 0.6667 5.8 0.935 Contact Map
2wcvA 7 0.3333 4 0.939 Contact Map
1pcfA 2 0.156 3.8 0.94 Contact Map
3j38T 1 0.6879 3.8 0.94 Contact Map
4ujpU 1 0.6099 3.7 0.941 Contact Map
3e7nA 6 0.3333 3.4 0.941 Contact Map
2eixA 2 0.4539 2.3 0.947 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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