GREMLIN Database
EMP70 - Endomembrane protein 70
PFAM: PF02990 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 506 (499)
Sequences: 1542 (983)
Seq/√Len: 44.0
META: 0.28

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
46_E49_K7.4831.00
352_G355_L6.0011.00
303_A376_G5.7391.00
107_L154_V5.3741.00
127_V165_S4.6381.00
112_D159_S4.4501.00
57_T60_D4.4271.00
253_V305_L4.2911.00
38_Y111_L4.0791.00
48_C142_C4.0331.00
5_Y13_P3.6321.00
306_Y311_G3.6211.00
53_T153_E3.5611.00
76_W113_F3.4901.00
455_C482_G3.4451.00
110_H157_T3.3201.00
78_V115_I3.2821.00
119_K164_E3.2681.00
237_G390_N3.1931.00
302_S317_N3.1681.00
298_A321_T3.1431.00
76_W93_F3.1231.00
114_V163_E3.0301.00
252_L479_F3.0041.00
318_T373_S2.9881.00
41_K44_E2.9551.00
55_T153_E2.8231.00
302_S321_T2.6811.00
40_L162_W2.6671.00
45_D163_E2.6651.00
53_T155_T2.6381.00
116_L163_E2.6041.00
483_G486_A2.5611.00
11_C52_C2.5581.00
76_W111_L2.5451.00
17_I35_N2.4791.00
289_V293_L2.4621.00
61_A65_K2.4191.00
257_V301_V2.4061.00
40_L115_I2.3341.00
447_V450_I2.3311.00
351_F355_L2.3281.00
172_S175_D2.2751.00
45_D161_K2.2571.00
356_A359_L2.2361.00
112_D161_K2.2341.00
39_E49_K2.1371.00
43_L117_Y2.1161.00
69_K105_Y2.0620.99
42_M126_I2.0560.99
81_L177_Y2.0280.99
439_Y443_F2.0190.99
252_L325_F1.9810.99
393_P472_Y1.9790.99
238_D241_R1.9570.99
116_L127_V1.9520.99
449_I453_I1.9200.99
33_I77_I1.8950.99
293_L297_V1.8830.99
112_D134_D1.8790.99
111_L131_V1.8740.99
429_F495_Y1.8330.99
248_L324_L1.8050.98
40_L78_V1.7910.98
484_S487_L1.7890.98
121_E124_E1.7830.98
481_T484_S1.7710.98
247_M250_S1.7670.98
466_Q475_W1.7630.98
330_F334_F1.7580.98
41_K46_E1.7500.98
411_L487_L1.6980.98
82_P173_R1.6940.98
333_F349_V1.6930.98
338_L342_A1.6860.97
10_F95_L1.6720.97
58_K62_K1.6440.97
13_P17_I1.6430.97
65_K105_Y1.6410.97
247_M317_N1.6360.97
10_F64_F1.6180.97
77_I80_N1.6100.97
9_P60_D1.6060.97
338_L341_W1.5450.96
117_Y162_W1.5420.96
84_A89_Y1.5360.96
420_A424_E1.5190.95
334_F354_M1.5160.95
463_T481_T1.5100.95
276_S279_N1.5070.95
241_R394_R1.5060.95
5_Y8_L1.5030.95
114_V161_K1.4970.95
81_L173_R1.4950.95
74_V95_L1.4860.95
32_R350_P1.4830.95
180_M347_G1.4790.95
221_Y235_V1.4730.94
188_H424_E1.4670.94
332_I335_V1.4600.94
23_N80_N1.4570.94
203_S457_E1.4520.94
334_F338_L1.4490.94
67_A95_L1.4230.93
415_I419_G1.4150.93
17_I126_I1.4140.93
405_R408_P1.4080.93
54_K60_D1.4080.93
408_P412_L1.4070.93
116_L128_G1.4060.93
12_K17_I1.4030.93
2_Y503_I1.3970.93
25_G281_G1.3950.93
297_V301_V1.3930.93
47_T159_S1.3820.92
217_D233_K1.3800.92
289_V359_L1.3790.92
330_F365_S1.3770.92
490_F494_I1.3740.92
252_L260_L1.3730.92
78_V129_F1.3720.92
427_F439_Y1.3720.92
307_K376_G1.3680.92
118_H127_V1.3600.92
321_T361_W1.3550.92
394_R397_P1.3520.91
291_Y297_V1.3420.91
64_F156_F1.3390.91
285_T289_V1.3170.90
355_L359_L1.3050.90
95_L105_Y1.3020.90
31_D36_S1.3020.90
249_L478_S1.2990.90
127_V170_W1.2900.89
332_I336_L1.2900.89
46_E159_S1.2840.89
192_I447_V1.2730.89
461_V468_C1.2700.89
275_L352_G1.2690.89
40_L113_F1.2600.88
236_H389_T1.2570.88
423_I485_T1.2570.88
308_T385_H1.2570.88
496_Y501_L1.2400.87
201_F205_M1.2390.87
240_F386_P1.2370.87
115_I126_I1.2130.86
471_D478_S1.2120.86
190_F419_G1.2110.86
224_L227_E1.2080.86
191_S194_N1.2040.86
214_L218_I1.2000.86
298_A302_S1.1970.86
8_L64_F1.1930.85
16_G259_L1.1880.85
254_G302_S1.1840.85
250_S305_L1.1750.84
38_Y51_L1.1740.84
47_T161_K1.1740.84
257_V297_V1.1740.84
497_F504_T1.1640.84
188_H438_Y1.1630.84
255_S324_L1.1590.84
56_L61_A1.1520.83
426_Y447_V1.1480.83
416_L419_G1.1430.83
318_T322_A1.1370.82
151_E355_L1.1350.82
248_L255_S1.1350.82
261_V294_T1.1260.82
9_P64_F1.1250.82
205_M208_M1.1250.82
124_E291_Y1.1240.82
401_P406_P1.1240.82
205_M415_I1.1230.82
50_V155_T1.1210.82
166_D396_I1.1200.81
409_S462_L1.1100.81
303_A373_S1.1000.80
348_A352_G1.1000.80
402_W458_V1.0960.80
440_V447_V1.0900.80
245_N248_L1.0900.80
238_D433_W1.0890.80
322_A369_V1.0810.79
128_G165_S1.0810.79
401_P404_L1.0800.79
124_E140_T1.0770.79
248_L483_G1.0770.79
63_F67_A1.0740.79
44_E57_T1.0730.79
27_V32_R1.0720.79
169_K172_S1.0690.78
334_F341_W1.0670.78
26_E188_H1.0670.78
210_L461_V1.0660.78
226_E263_T1.0640.78
466_Q481_T1.0620.78
247_M251_V1.0590.78
162_W188_H1.0540.77
79_D82_P1.0520.77
10_F37_P1.0510.77
294_T297_V1.0460.77
311_G345_S1.0450.77
217_D232_W1.0440.77
419_G425_L1.0350.76
499_T502_E1.0350.76
232_W241_R1.0340.76
43_L161_K1.0200.75
77_I93_F1.0180.75
216_R219_A1.0170.75
304_R376_G1.0160.75
262_M362_F1.0150.75
207_A457_E1.0080.74
340_L347_G1.0010.74
240_F299_G1.0010.74
140_T143_P0.9980.73
109_N135_S0.9980.73
236_H386_P0.9950.73
283_L448_F0.9930.73
203_S216_R0.9890.73
254_G403_Y0.9750.72
126_I305_L0.9700.71
205_M215_R0.9680.71
288_I484_S0.9630.71
313_N316_K0.9620.71
420_A477_R0.9590.70
262_M283_L0.9580.70
2_Y108_N0.9580.70
414_G418_F0.9550.70
337_N348_A0.9530.70
422_F429_F0.9510.70
76_W83_A0.9490.70
271_L437_I0.9440.69
268_L288_I0.9430.69
457_E488_Y0.9430.69
273_G280_R0.9400.69
261_V297_V0.9380.69
194_N418_F0.9370.69
397_P470_E0.9320.68
53_T366_V0.9300.68
385_H389_T0.9290.68
462_L483_G0.9290.68
54_K57_T0.9290.68
271_L445_F0.9260.68
83_A113_F0.9240.67
494_I497_F0.9240.67
67_A70_D0.9230.67
217_D231_G0.9210.67
106_Y428_I0.9210.67
92_G96_G0.9200.67
177_Y188_H0.9200.67
228_E425_L0.9190.67
140_T144_K0.9190.67
261_V268_L0.9180.67
56_L64_F0.9170.67
373_S454_T0.9160.67
307_K315_K0.9130.66
26_E31_D0.9100.66
81_L188_H0.9080.66
218_I303_A0.9080.66
292_V298_A0.9070.66
15_G18_K0.9070.66
466_Q477_R0.9060.66
156_F164_E0.9040.66
45_D164_E0.9030.66
447_V451_L0.9000.65
279_N283_L0.8990.65
413_G482_G0.8980.65
93_F111_L0.8950.65
194_N419_G0.8950.65
61_A152_T0.8930.65
218_I222_N0.8920.65
250_S254_G0.8900.64
265_V290_L0.8900.64
116_L130_E0.8890.64
164_E169_K0.8880.64
233_K464_Y0.8870.64
73_R156_F0.8850.64
238_D389_T0.8840.64
290_L297_V0.8820.64
267_L360_L0.8820.64
214_L217_D0.8780.63
23_N289_V0.8750.63
208_M419_G0.8730.63
12_K37_P0.8710.63
241_R397_P0.8710.63
303_A307_K0.8690.63
42_M162_W0.8660.62
265_V360_L0.8610.62
39_E45_D0.8600.62
241_R470_E0.8580.62
255_S319_L0.8550.61
308_T382_A0.8540.61
466_Q483_G0.8510.61
497_F503_I0.8490.61
139_L159_S0.8470.61
491_L494_I0.8460.61
241_R386_P0.8450.60
25_G28_L0.8450.60
26_E177_Y0.8440.60
238_D394_R0.8430.60
197_V212_R0.8420.60
60_D63_F0.8410.60
330_F362_F0.8390.60
416_L450_I0.8380.60
211_L218_I0.8370.60
130_E485_T0.8330.59
74_V130_E0.8280.59
79_D92_G0.8270.59
280_R350_P0.8260.59
285_T328_I0.8250.59
109_N174_W0.8250.59
229_E236_H0.8240.58
124_E144_K0.8220.58
372_G376_G0.8220.58
318_T370_F0.8220.58
66_E70_D0.8210.58
138_H141_T0.8200.58
213_T429_F0.8180.58
262_M294_T0.8180.58
309_F483_G0.8160.58
207_A267_L0.8150.58
84_A177_Y0.8140.58
13_P31_D0.8130.57
394_R470_E0.8120.57
416_L465_F0.8120.57
461_V471_D0.8120.57
190_F427_F0.8110.57
238_D386_P0.8110.57
309_F475_W0.8100.57
250_S302_S0.8100.57
296_F375_F0.8100.57
324_L328_I0.8080.57
295_G369_V0.8070.57
26_E29_F0.8070.57
345_S348_A0.8060.57
318_T492_Y0.8050.57
19_K34_E0.8040.57
433_W493_S0.8040.57
2_Y94_P0.8040.57
126_I129_F0.8030.57
61_A405_R0.8020.56
140_T324_L0.8010.56
56_L152_T0.8000.56
120_D125_R0.8000.56
208_M465_F0.7960.56
187_I444_L0.7950.56
301_V437_I0.7940.56
485_T489_V0.7940.56
282_S358_L0.7930.56
229_E235_V0.7920.55
410_I480_L0.7910.55
239_V397_P0.7910.55
94_P108_N0.7910.55
333_F435_H0.7910.55
300_Y321_T0.7910.55
424_E433_W0.7900.55
81_L438_Y0.7880.55
260_L263_T0.7880.55
156_F320_L0.7860.55
83_A89_Y0.7860.55
134_D159_S0.7840.55
108_N144_K0.7840.55
39_E51_L0.7810.54
41_K264_L0.7780.54
22_E26_E0.7760.54
354_M432_I0.7760.54
285_T406_P0.7760.54
168_I172_S0.7730.54
275_L486_A0.7730.54
108_N111_L0.7730.54
310_G359_L0.7730.54
56_L60_D0.7720.54
410_I498_F0.7680.53
141_T145_N0.7640.53
319_L323_L0.7620.53
419_G439_Y0.7590.52
157_T173_R0.7580.52
309_F459_T0.7580.52
413_G454_T0.7560.52
254_G258_Q0.7540.52
333_F373_S0.7530.52
1_P203_S0.7530.52
201_F419_G0.7520.52
310_G363_G0.7510.52
266_T362_F0.7510.52
45_D87_K0.7490.51
197_V473_R0.7490.51
119_K166_D0.7470.51
349_V354_M0.7460.51
391_Q395_Q0.7440.51
192_I423_I0.7440.51
48_C133_P0.7440.51
43_L95_L0.7420.51
188_H442_G0.7420.51
237_G389_T0.7400.50
161_K405_R0.7380.50
426_Y450_I0.7370.50
197_V419_G0.7360.50
194_N201_F0.7350.50
223_E253_V0.7320.50
133_P218_I0.7310.50
16_G37_P0.7310.50
13_P336_L0.7280.49
344_G496_Y0.7260.49
108_N133_P0.7250.49
21_S339_F0.7250.49
191_S458_V0.7240.49
288_I339_F0.7200.49
157_T357_L0.7200.49
404_L466_Q0.7200.49
36_S76_W0.7180.48
352_G356_A0.7180.48
337_N345_S0.7170.48
169_K325_F0.7170.48
277_P394_R0.7150.48
400_Q469_A0.7150.48
207_A263_T0.7100.48
151_E154_V0.7080.47
494_I498_F0.7070.47
257_V491_L0.7060.47
126_I274_F0.7050.47
312_K452_I0.7040.47
389_T395_Q0.7030.47
455_C503_I0.7030.47
259_L274_F0.7030.47
198_I205_M0.7030.47
227_E449_I0.7030.47
31_D420_A0.7010.47
355_L379_K0.6990.47
107_L348_A0.6980.46
337_N351_F0.6980.46
335_V494_I0.6950.46
218_I406_P0.6950.46
422_F461_V0.6940.46
462_L466_Q0.6940.46
50_V56_L0.6930.46
166_D331_G0.6920.46
210_L421_I0.6910.46
107_L356_A0.6900.46
205_M454_T0.6870.45
238_D397_P0.6870.45
255_S259_L0.6860.45
368_L396_I0.6860.45
188_H440_V0.6840.45
484_S492_Y0.6840.45
214_L320_L0.6830.45
40_L213_T0.6830.45
419_G443_F0.6820.45
195_S416_L0.6810.45
456_A460_I0.6810.45
201_F206_V0.6780.45
9_P57_T0.6770.44
421_I433_W0.6770.44
273_G283_L0.6750.44
383_I429_F0.6750.44
421_I488_Y0.6720.44
151_E489_V0.6700.44
400_Q413_G0.6700.44
62_K65_K0.6690.44
431_S436_K0.6690.44
56_L154_V0.6690.44
293_L359_L0.6690.44
65_K220_R0.6670.44
9_P20_K0.6660.43
340_L503_I0.6650.43
190_F201_F0.6650.43
408_P432_I0.6650.43
307_K384_E0.6650.43
61_A225_D0.6640.43
327_G455_C0.6630.43
254_G306_Y0.6630.43
40_L160_V0.6610.43
451_L488_Y0.6600.43
249_L479_F0.6590.43
18_K69_K0.6590.43
97_Y157_T0.6580.43
9_P29_F0.6580.43
311_G376_G0.6580.43
127_V319_L0.6580.43
28_L206_V0.6580.43
215_R308_T0.6570.43
414_G488_Y0.6570.43
244_R473_R0.6570.43
201_F500_K0.6560.42
302_S345_S0.6550.42
116_L165_S0.6540.42
232_W239_V0.6540.42
315_K370_F0.6530.42
415_I460_I0.6520.42
190_F194_N0.6500.42
233_K367_P0.6490.42
259_L389_T0.6490.42
250_S344_G0.6470.42
307_K453_I0.6460.42
232_W238_D0.6460.42
311_G317_N0.6460.42
232_W240_F0.6440.41
2_Y41_K0.6430.41
447_V457_E0.6420.41
185_H443_F0.6400.41
107_L156_F0.6390.41
144_K147_E0.6380.41
112_D132_T0.6380.41
421_I485_T0.6370.41
188_H325_F0.6370.41
451_L493_S0.6370.41
239_V394_R0.6360.41
46_E249_L0.6360.41
450_I459_T0.6340.40
421_I451_L0.6330.40
246_P249_L0.6310.40
97_Y101_K0.6310.40
126_I351_F0.6310.40
56_L70_D0.6280.40
49_K159_S0.6280.40
305_L317_N0.6260.40
349_V369_V0.6250.40
418_F488_Y0.6240.39
36_S93_F0.6240.39
325_F345_S0.6230.39
335_V355_L0.6230.39
207_A211_L0.6220.39
22_E33_I0.6200.39
328_I344_G0.6200.39
393_P431_S0.6180.39
29_F32_R0.6160.39
244_R393_P0.6160.39
291_Y460_I0.6160.39
202_L418_F0.6160.39
16_G310_G0.6160.39
239_V368_L0.6150.39
40_L335_V0.6140.39
124_E245_N0.6140.39
275_L286_A0.6130.38
353_T357_L0.6120.38
260_L265_V0.6110.38
359_L473_R0.6110.38
269_F274_F0.6100.38
205_M422_F0.6100.38
57_T318_T0.6090.38
166_D487_L0.6090.38
89_Y287_M0.6090.38
318_T369_V0.6090.38
438_Y442_G0.6070.38
308_T383_I0.6060.38
37_P51_L0.6060.38
40_L51_L0.6050.38
260_L452_I0.6040.38
412_L423_I0.6040.38
224_L364_I0.6040.38
231_G238_D0.6040.38
246_P305_L0.6020.37
231_G234_L0.6020.37
482_G486_A0.6010.37
71_D356_A0.6000.37
5_Y9_P0.6000.37
307_K382_A0.5990.37
71_D489_V0.5990.37
125_R170_W0.5980.37
473_R503_I0.5970.37
293_L364_I0.5960.37
240_F361_W0.5960.37
126_I185_H0.5940.37
115_I257_V0.5940.37
285_T390_N0.5940.37
262_M360_L0.5930.37
125_R236_H0.5930.37
272_L412_L0.5930.37
252_L282_S0.5920.37
197_V205_M0.5910.37
89_Y116_L0.5910.37
430_S448_F0.5910.37
46_E137_K0.5900.36
138_H159_S0.5890.36
175_D178_L0.5880.36
302_S306_Y0.5880.36
75_N190_F0.5870.36
5_Y42_M0.5860.36
269_F275_L0.5840.36
55_T449_I0.5840.36
310_G396_I0.5840.36
41_K113_F0.5840.36
324_L500_K0.5820.36
198_I450_I0.5820.36
89_Y92_G0.5810.36
127_V262_M0.5800.36
138_H155_T0.5800.36
118_H128_G0.5800.36
50_V53_T0.5780.35
124_E319_L0.5780.35
339_F486_A0.5760.35
224_L303_A0.5750.35
467_L470_E0.5740.35
330_F351_F0.5730.35
371_L493_S0.5730.35
153_E159_S0.5730.35
168_I354_M0.5720.35
2_Y30_G0.5720.35
214_L229_E0.5710.35
288_I359_L0.5710.35
232_W243_P0.5710.35
332_I396_I0.5690.35
10_F56_L0.5690.35
267_L329_V0.5670.34
319_L389_T0.5670.34
305_L308_T0.5670.34
45_D53_T0.5670.34
32_R197_V0.5660.34
341_W348_A0.5650.34
195_S425_L0.5650.34
1_P129_F0.5650.34
144_K166_D0.5650.34
241_R393_P0.5640.34
233_K470_E0.5640.34
90_S113_F0.5630.34
24_L330_F0.5630.34
293_L296_F0.5620.34
269_F428_I0.5610.34
426_Y430_S0.5610.34
135_S174_W0.5610.34
116_L168_I0.5600.34
194_N439_Y0.5600.34
302_S361_W0.5600.34
106_Y120_D0.5600.34
395_Q472_Y0.5590.34
244_R260_L0.5580.34
238_D470_E0.5570.34
248_L298_A0.5560.33
12_K54_K0.5560.33
73_R91_T0.5550.33
341_W351_F0.5540.33
286_A325_F0.5540.33
308_T328_I0.5530.33
40_L102_D0.5530.33
179_D182_P0.5530.33
213_T216_R0.5530.33
464_Y470_E0.5520.33
71_D421_I0.5520.33
307_K449_I0.5510.33
38_Y59_E0.5510.33
24_L349_V0.5510.33
249_L253_V0.5510.33
272_L293_L0.5510.33
47_T114_V0.5500.33
201_F420_A0.5480.33
157_T216_R0.5480.33
302_S373_S0.5480.33
48_C109_N0.5470.33
193_I197_V0.5470.33
186_Q450_I0.5460.33
101_K335_V0.5450.33
272_L362_F0.5440.32
13_P37_P0.5440.32
169_K268_L0.5440.32
202_L450_I0.5430.32
208_M400_Q0.5430.32
432_I456_A0.5430.32
269_F392_I0.5420.32
108_N204_G0.5420.32
258_Q345_S0.5410.32
148_L371_L0.5400.32
229_E458_V0.5390.32
126_I179_D0.5390.32
91_T159_S0.5380.32
89_Y128_G0.5380.32
206_V413_G0.5380.32
401_P458_V0.5370.32
249_L252_L0.5360.32
195_S438_Y0.5350.32
242_P428_I0.5350.32
57_T151_E0.5340.32
217_D464_Y0.5340.32
144_K331_G0.5340.32
440_V461_V0.5340.32
252_L497_F0.5330.32
218_I221_Y0.5320.31
436_K482_G0.5320.31
44_E264_L0.5320.31
157_T480_L0.5310.31
456_A462_L0.5310.31
301_V431_S0.5310.31
198_I454_T0.5300.31
200_L255_S0.5300.31
190_F208_M0.5290.31
330_F361_W0.5270.31
432_I498_F0.5270.31
487_L491_L0.5260.31
258_Q321_T0.5240.31
148_L460_I0.5220.31
249_L278_S0.5220.31
141_T144_K0.5220.31
206_V457_E0.5220.31
65_K69_K0.5210.31
162_W384_E0.5210.31
287_M456_A0.5210.31
198_I419_G0.5210.31
132_T355_L0.5200.30
18_K22_E0.5200.30
153_E268_L0.5200.30
12_K200_L0.5200.30
248_L320_L0.5190.30
97_Y156_F0.5190.30
162_W320_L0.5190.30
128_G135_S0.5180.30
439_Y442_G0.5180.30
450_I465_F0.5180.30
221_Y388_R0.5170.30
142_C174_W0.5170.30
272_L383_I0.5170.30
262_M273_G0.5160.30
55_T253_V0.5160.30
115_I162_W0.5160.30
434_L484_S0.5150.30
203_S409_S0.5150.30
445_F488_Y0.5140.30
176_K267_L0.5140.30
364_I368_L0.5140.30
170_W441_F0.5130.30
322_A363_G0.5120.30
213_T275_L0.5120.30
428_I433_W0.5100.30
473_R481_T0.5100.30
114_V166_D0.5100.30
124_E328_I0.5100.30
188_H195_S0.5090.30
285_T412_L0.5090.30
252_L456_A0.5090.30
280_R326_P0.5080.29
230_S401_P0.5080.29
134_D143_P0.5080.29
267_L293_L0.5070.29
6_S20_K0.5070.29
45_D210_L0.5060.29
119_K124_E0.5060.29
321_T369_V0.5060.29
124_E151_E0.5050.29
20_K35_N0.5050.29
162_W297_V0.5050.29
27_V350_P0.5040.29
87_K297_V0.5040.29
424_E427_F0.5040.29
114_V132_T0.5030.29
353_T432_I0.5030.29
126_I171_A0.5010.29
182_P475_W0.5000.29
253_V342_A0.5000.29
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2kncB 1 0.1462 35.7 0.977 Contact Map
2kncA 1 0.1028 19 0.98 Contact Map
2z73A 2 0.5277 8 0.983 Contact Map
3rlfF 1 0.168 6.8 0.984 Contact Map
2c35A 1 0.1364 4.4 0.985 Contact Map
1pw4A 1 0.4368 4.4 0.985 Contact Map
4dveA 3 0.3024 4.2 0.985 Contact Map
3axsA 2 0.1265 3.5 0.986 Contact Map
2m3eA 1 0.0949 3.3 0.986 Contact Map
1x0gA 4 0.1798 3.2 0.986 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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