GREMLIN Database
G3P_acyltransf - Glycerol-3-phosphate acyltransferase
PFAM: PF02660 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 163 (163)
Sequences: 41298 (27317)
Seq/√Len: 2139.6
META: 0.907

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
10_F51_L3.5431.00
69_G96_V3.2531.00
57_A99_A2.9141.00
11_G31_I2.6451.00
115_V128_V2.5741.00
26_V39_T2.5551.00
33_A49_L2.3351.00
2_A68_A2.0861.00
21_I26_V2.0381.00
77_L89_G2.0321.00
9_P82_L2.0311.00
154_W157_R2.0101.00
57_A61_L1.9981.00
37_L45_G1.9041.00
3_Y80_V1.8951.00
101_A104_A1.8741.00
127_L153_I1.8211.00
56_G92_T1.8141.00
121_Y163_L1.8081.00
137_A145_A1.7951.00
12_Y82_L1.7651.00
7_S81_F1.7611.00
5_L59_A1.7441.00
79_P82_L1.6981.00
157_R161_R1.6911.00
90_V152_I1.6581.00
77_L155_R1.6401.00
74_L78_F1.6041.00
111_V136_L1.5721.00
8_I13_L1.5481.00
36_V48_T1.5451.00
130_A152_I1.5261.00
18_F44_A1.5051.00
111_V132_A1.4731.00
14_L44_A1.4471.00
73_V93_A1.4431.00
33_A91_A1.4291.00
63_A68_A1.4251.00
77_L151_L1.4081.00
107_I136_L1.4041.00
22_D25_E1.3791.00
9_P31_I1.3721.00
73_V148_L1.3581.00
73_V77_L1.3551.00
7_S80_V1.3281.00
54_L57_A1.3211.00
11_G48_T1.3051.00
12_Y31_I1.2881.00
90_V126_S1.2851.00
19_G44_A1.2681.00
14_L51_L1.2681.00
98_L105_A1.2571.00
23_I31_I1.2531.00
30_N88_K1.2501.00
116_A125_A1.2431.00
131_A153_I1.2341.00
2_A71_A1.2311.00
115_V119_T1.2291.00
134_P149_A1.2291.00
61_L65_L1.2241.00
158_A162_R1.2171.00
132_A136_L1.2161.00
36_V40_L1.2131.00
31_I82_L1.2051.00
53_A98_L1.1971.00
121_Y124_L1.1911.00
12_Y24_R1.1881.00
37_L42_K1.1841.00
15_G19_G1.1831.00
94_L105_A1.1731.00
59_A68_A1.1551.00
158_A161_R1.1471.00
15_G21_I1.1451.00
133_L145_A1.1311.00
59_A72_A1.1261.00
13_L17_L1.1211.00
49_L53_A1.1171.00
112_W122_V1.1151.00
149_A153_I1.1131.00
61_L64_R1.1131.00
40_L44_A1.1101.00
15_G40_L1.1021.00
60_V64_R1.1011.00
42_K46_A1.0911.00
60_V99_A1.0841.00
12_Y23_I1.0811.00
127_L160_I1.0751.00
4_L81_F1.0681.00
138_L142_L1.0451.00
34_T122_V1.0361.00
103_L106_L1.0301.00
41_G44_A1.0261.00
43_K47_L1.0241.00
70_L147_L0.9911.00
142_L146_L0.9891.00
49_L91_A0.9831.00
113_L117_A0.9791.00
21_I40_L0.9591.00
47_L51_L0.9481.00
134_P142_L0.9431.00
115_V124_L0.9401.00
15_G36_V0.9391.00
108_A133_L0.9381.00
32_G35_N0.9201.00
134_P138_L0.9151.00
108_A129_A0.9141.00
112_W116_A0.9141.00
94_L129_A0.9001.00
91_A95_G0.8991.00
77_L152_I0.8991.00
143_L147_L0.8961.00
23_I36_V0.8911.00
69_G72_A0.8871.00
136_L140_L0.8871.00
135_L139_L0.8871.00
36_V44_A0.8861.00
12_Y15_G0.8791.00
93_A148_L0.8731.00
3_Y79_P0.8671.00
50_L54_L0.8621.00
79_P85_K0.8601.00
142_L145_A0.8591.00
115_V125_A0.8541.00
14_L48_T0.8491.00
52_D76_H0.8451.00
54_L59_A0.8441.00
10_F14_L0.8381.00
104_A137_A0.8291.00
122_V126_S0.8261.00
2_A6_G0.8241.00
21_I25_E0.8191.00
44_A47_L0.8151.00
137_A142_L0.8141.00
73_V96_V0.8091.00
46_A50_L0.8041.00
131_A149_A0.8041.00
71_A74_L0.8011.00
150_L154_W0.7911.00
134_P146_L0.7911.00
15_G23_I0.7871.00
20_G41_G0.7841.00
94_L109_L0.7801.00
60_V63_A0.7731.00
61_L99_A0.7651.00
11_G30_N0.7561.00
73_V89_G0.7471.00
111_V115_V0.7331.00
39_T43_K0.7321.00
112_W125_A0.7321.00
14_L47_L0.7291.00
106_L110_A0.7291.00
14_L18_F0.7271.00
4_L7_S0.7251.00
49_L94_L0.7221.00
53_A94_L0.7221.00
67_L71_A0.7141.00
114_L118_L0.7021.00
24_R82_L0.6971.00
2_A72_A0.6951.00
123_S163_L0.6941.00
64_R99_A0.6921.00
62_L66_L0.6911.00
27_G35_N0.6791.00
78_F155_R0.6771.00
93_A152_I0.6761.00
19_G40_L0.6761.00
130_A153_I0.6761.00
101_A137_A0.6731.00
141_L145_A0.6721.00
128_V131_A0.6661.00
62_L65_L0.6621.00
119_T124_L0.6611.00
138_L146_L0.6581.00
56_G96_V0.6551.00
72_A92_T0.6521.00
15_G26_V0.6501.00
144_F148_L0.6491.00
124_L128_V0.6481.00
93_A130_A0.6451.00
56_G95_G0.6451.00
116_A122_V0.6431.00
97_L105_A0.6361.00
77_L93_A0.6341.00
5_L10_F0.6331.00
59_A63_A0.6321.00
102_P106_L0.6271.00
134_P145_A0.6191.00
33_A45_G0.6191.00
60_V96_V0.6171.00
70_L144_F0.6151.00
40_L43_K0.6121.00
12_Y16_R0.6101.00
103_L107_I0.6041.00
7_S79_P0.6041.00
28_S34_T0.5971.00
37_L40_L0.5971.00
96_V144_F0.5951.00
53_A57_A0.5921.00
34_T123_S0.5911.00
97_L133_L0.5881.00
95_G99_A0.5861.00
78_F151_L0.5841.00
14_L17_L0.5821.00
123_S127_L0.5731.00
89_G155_R0.5731.00
54_L58_L0.5721.00
141_L144_F0.5691.00
50_L53_A0.5651.00
115_V118_L0.5651.00
17_L21_I0.5621.00
13_L82_L0.5531.00
151_L155_R0.5501.00
68_A71_A0.5471.00
97_L145_A0.5471.00
108_A132_A0.5401.00
155_R158_A0.5401.00
24_R79_P0.5371.00
154_W158_A0.5361.00
122_V127_L0.5331.00
4_L80_V0.5331.00
97_L148_L0.5321.00
1_L5_L0.5311.00
15_G18_F0.5301.00
128_V132_A0.5301.00
146_L150_L0.5281.00
9_P12_Y0.5271.00
56_G60_V0.5231.00
107_I140_L0.5201.00
58_L61_L0.5171.00
137_A140_L0.5161.00
56_G72_A0.5151.00
143_L146_L0.5141.00
112_W129_A0.5141.00
136_L139_L0.5141.00
36_V39_T0.5121.00
117_A120_R0.5101.00
7_S82_L0.5061.00
119_T125_A0.5051.00
2_A5_L0.5041.00
37_L46_A0.5031.00
132_A135_L0.5031.00
107_I110_A0.5031.00
30_N35_N0.5031.00
153_I157_R0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2f95B 2 0.3252 3.5 0.948 Contact Map
2mfrA 1 0.2945 3.4 0.948 Contact Map
2bzwB 1 0.1656 1.4 0.959 Contact Map
4dveA 3 0.4724 1.2 0.96 Contact Map
2j5dA 2 0.2699 1.2 0.96 Contact Map
2l2tA 2 0.2638 1.1 0.961 Contact Map
2jwaA 2 0.2699 0.9 0.964 Contact Map
3wu2F 1 0.0982 0.8 0.964 Contact Map
3zuxA 1 0.4785 0.8 0.964 Contact Map
2wscI 1 0.184 0.8 0.964 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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