GREMLIN Database
FliD_N - Flagellar hook-associated protein 2 N-terminus
PFAM: PF02465 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 97 (96)
Sequences: 27080 (21017)
Seq/√Len: 2145.0
META: 0.89

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
4_D7_S3.1191.00
7_S11_Q2.3751.00
6_N10_D2.3111.00
21_T24_Q2.0381.00
19_P22_R1.9531.00
5_T9_V1.8621.00
17_R20_L1.8541.00
11_Q14_A1.8151.00
11_Q15_A1.7921.00
36_A39_S1.7911.00
28_T32_A1.7161.00
18_A22_R1.6921.00
18_A21_T1.6611.00
65_A75_A1.6591.00
34_I38_G1.6551.00
39_S43_K1.6481.00
20_L24_Q1.6481.00
10_D14_A1.6081.00
9_V13_M1.6051.00
69_D72_V1.5321.00
24_Q27_Q1.4991.00
30_L33_K1.4801.00
14_A21_T1.4621.00
73_V88_I1.4501.00
38_G41_K1.4441.00
31_Q34_I1.4321.00
41_K45_S1.4241.00
50_A53_A1.4181.00
15_A18_A1.4051.00
35_S38_G1.3871.00
14_A17_R1.3811.00
43_K46_A1.3811.00
27_Q31_Q1.3461.00
28_T31_Q1.3411.00
63_R83_A1.2821.00
21_T25_T1.2711.00
45_S48_Q1.2691.00
30_L34_I1.2601.00
48_Q52_S1.2541.00
13_M17_R1.2511.00
22_R25_T1.2431.00
55_S59_T1.2321.00
13_M16_E1.2291.00
8_I12_L1.1791.00
63_R77_A1.1751.00
29_T33_K1.1681.00
5_T8_I1.1551.00
45_S49_T1.1521.00
56_S59_T1.1111.00
17_R21_T1.0831.00
26_Q29_T1.0751.00
24_Q28_T1.0531.00
32_A35_S1.0441.00
70_S74_T1.0431.00
25_T29_T1.0371.00
27_Q30_L1.0341.00
12_L15_A1.0031.00
67_S73_V1.0031.00
52_S55_S0.9841.00
42_S45_S0.9831.00
77_A81_A0.9621.00
14_A18_A0.9501.00
67_S72_V0.9461.00
31_Q35_S0.9161.00
25_T28_T0.9071.00
46_A50_A0.8971.00
65_A77_A0.8931.00
46_A49_T0.8811.00
26_Q30_L0.8791.00
59_T62_A0.8641.00
22_R26_Q0.8601.00
53_A56_S0.8531.00
29_T32_A0.8491.00
52_S56_S0.8491.00
16_E19_P0.8341.00
67_S70_S0.8321.00
7_S10_D0.8321.00
49_T52_S0.8251.00
92_Q95_T0.8091.00
57_A61_N0.8091.00
3_L8_I0.8051.00
12_L16_E0.8051.00
35_S39_S0.7941.00
23_L30_L0.7901.00
42_S46_A0.7781.00
20_L23_L0.7751.00
54_L60_F0.7671.00
59_T63_R0.7641.00
66_T70_S0.7581.00
39_S42_S0.7531.00
5_T12_L0.7451.00
67_S75_A0.7401.00
23_L27_Q0.7351.00
13_M20_L0.7001.00
15_A19_P0.7001.00
6_N9_V0.6951.00
53_A59_T0.6901.00
23_L26_Q0.6881.00
32_A36_A0.6721.00
40_L43_K0.6681.00
74_T77_A0.6591.00
8_I11_Q0.6551.00
86_Y89_E0.6481.00
72_V75_A0.6351.00
34_I41_K0.6341.00
19_P23_L0.6331.00
87_S95_T0.6291.00
57_A60_F0.6281.00
49_T53_A0.6221.00
72_V90_V0.6181.00
13_M18_A0.6171.00
9_V12_L0.6081.00
47_L51_A0.6061.00
25_T32_A0.5981.00
63_R82_A0.5971.00
38_G42_S0.5971.00
68_S73_V0.5891.00
6_N11_Q0.5881.00
89_E92_Q0.5871.00
72_V89_E0.5831.00
48_Q51_A0.5821.00
41_K48_Q0.5691.00
58_S61_N0.5551.00
38_G45_S0.5531.00
37_L41_K0.5471.00
33_K36_A0.5451.00
8_I15_A0.5381.00
81_A84_G0.5311.00
4_D8_I0.5291.00
5_T13_M0.5291.00
54_L59_T0.5271.00
50_A54_L0.5241.00
47_L50_A0.5221.00
90_V93_L0.5201.00
60_F63_R0.5191.00
65_A68_S0.5181.00
3_L6_N0.5151.00
41_K44_L0.5121.00
10_D13_M0.5041.00
20_L88_I0.5021.00
52_S59_T0.5021.00
53_A57_A0.5011.00
58_S62_A0.5011.00
5_T15_A0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3gw6A 3 0.3299 11.3 0.872 Contact Map
2vz4A 2 0.4536 8.3 0.879 Contact Map
1r8dA 2 0.5361 8.1 0.88 Contact Map
4u6uA 1 0.567 4.8 0.892 Contact Map
3n7nE 1 0.0103 4.7 0.892 Contact Map
2k5cA 1 0.6186 4.7 0.892 Contact Map
3e5nA 2 0.268 4.2 0.895 Contact Map
3tqtA 2 0.3711 4.2 0.895 Contact Map
4cwcA 2 0.299 4 0.896 Contact Map
3zg9B 1 0 3.8 0.897 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0052 seconds.