GREMLIN Database
FlgI - Flagellar P-ring protein
PFAM: PF02119 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 342 (341)
Sequences: 8543 (4980)
Seq/√Len: 269.7
META: 0.833

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
68_V103_T3.9511.00
114_A149_A3.8391.00
2_I180_I3.4331.00
13_D71_T3.3601.00
183_A223_L2.9561.00
78_P154_E2.8471.00
270_V283_V2.8271.00
164_S202_R2.8091.00
253_V330_L2.8081.00
61_K93_K2.7301.00
77_R197_D2.6861.00
187_A219_R2.6721.00
6_A180_I2.6381.00
7_S170_R2.6321.00
274_N277_S2.5561.00
212_Q215_A2.5451.00
175_T179_R2.4931.00
12_R152_E2.4241.00
269_Q283_V2.4011.00
232_R341_E2.3851.00
268_P285_R2.3791.00
188_F216_F2.3621.00
185_N193_A2.3511.00
203_V220_I2.2651.00
19_Y41_S2.2091.00
196_L202_R2.2061.00
206_P216_F2.1971.00
3_K173_D2.1831.00
180_I201_V2.1801.00
251_S337_Q2.1631.00
175_T221_E2.1351.00
120_L143_G2.1091.00
84_V116_A2.0781.00
269_Q285_R2.0721.00
181_A195_A2.0691.00
268_P284_P2.0551.00
179_R227_P2.0281.00
197_D200_T2.0131.00
271_S280_T2.0101.00
266_E286_T2.0041.00
233_V336_L1.9951.00
6_A167_L1.9841.00
310_V327_L1.9731.00
194_R202_R1.9011.00
195_A214_V1.8811.00
62_N88_S1.8591.00
188_F192_T1.8521.00
85_T142_V1.8331.00
72_L151_V1.8241.00
175_T218_A1.8221.00
172_P199_G1.8171.00
272_Q280_T1.8151.00
178_S182_D1.8081.00
169_L177_A1.7911.00
137_K292_E1.7701.00
31_S91_D1.7651.00
131_G286_T1.7401.00
307_Q311_R1.7391.00
14_N152_E1.7311.00
5_I225_V1.7031.00
76_A151_V1.6881.00
54_P57_D1.6881.00
3_K228_D1.6831.00
84_V149_A1.6811.00
17_V101_L1.6781.00
175_T222_N1.6651.00
131_G266_E1.6431.00
71_T81_R1.6281.00
8_V217_L1.6251.00
108_A115_V1.6221.00
268_P282_V1.6181.00
9_E166_R1.6031.00
31_S59_K1.5831.00
67_M101_L1.5781.00
180_I225_V1.5771.00
166_R202_R1.5741.00
174_F217_L1.5651.00
298_F316_L1.5451.00
35_T60_L1.5411.00
6_A221_E1.5321.00
130_G286_T1.5201.00
266_E284_P1.5141.00
166_R200_T1.5081.00
205_V213_R1.5001.00
70_A82_I1.4841.00
26_N140_P1.4771.00
2_I220_I1.4631.00
77_R200_T1.4631.00
130_G133_S1.4471.00
102_M108_A1.4471.00
1_R4_D1.4361.00
107_G113_Y1.4261.00
42_L60_L1.4151.00
8_V167_L1.3951.00
72_L155_V1.3941.00
11_V174_F1.3901.00
94_S122_V1.3901.00
87_S99_T1.3641.00
37_F60_L1.3621.00
250_I335_A1.3531.00
184_I223_L1.3501.00
31_S34_Q1.3311.00
236_N239_T1.3291.00
277_S280_T1.3261.00
177_A195_A1.3111.00
136_T140_P1.3061.00
109_D113_Y1.3001.00
297_L313_L1.2901.00
306_L310_V1.2821.00
244_M310_V1.2771.00
125_F137_K1.2561.00
271_S281_V1.2491.00
273_P280_T1.2481.00
177_A181_A1.2471.00
179_R228_D1.2431.00
19_Y65_A1.2401.00
2_I223_L1.2341.00
188_F219_R1.2261.00
189_G192_T1.2011.00
182_D186_A1.2001.00
41_S65_A1.2001.00
102_M115_V1.1991.00
230_P339_E1.1921.00
292_E321_R1.1821.00
218_A222_N1.1811.00
121_S342_V1.1731.00
7_S80_Q1.1691.00
259_N293_E1.1561.00
178_S215_A1.1251.00
206_P209_Y1.1231.00
133_S286_T1.1201.00
80_Q168_N1.1131.00
13_D81_R1.1111.00
77_R154_E1.1031.00
13_D150_I1.0981.00
271_S283_V1.0901.00
176_T227_P1.0871.00
272_Q278_G1.0831.00
21_L63_V1.0831.00
165_L217_L1.0801.00
135_V290_V1.0801.00
99_T102_M1.0761.00
125_F290_V1.0711.00
158_D161_Q1.0621.00
237_E321_R1.0591.00
267_T285_R1.0511.00
5_I180_I1.0431.00
262_V309_L1.0421.00
5_I227_P1.0391.00
256_A297_L1.0391.00
73_P76_A1.0381.00
159_F174_F1.0371.00
297_L300_L1.0361.00
1_R228_D1.0331.00
111_Q153_R1.0301.00
265_T285_R1.0301.00
139_H142_V1.0291.00
235_I324_I1.0131.00
172_P198_A1.0051.00
3_K221_E1.0051.00
42_L49_L1.0031.00
126_G140_P1.0031.00
60_L63_V0.9921.00
267_T287_D0.9901.00
176_T225_V0.9851.00
271_S277_S0.9821.00
167_L203_V0.9801.00
8_V165_L0.9781.00
133_S266_E0.9681.00
297_L323_L0.9671.00
180_I223_L0.9551.00
121_S237_E0.9541.00
2_I6_A0.9541.00
180_I184_I0.9521.00
181_A193_A0.9511.00
99_T142_V0.9511.00
176_T228_D0.9501.00
331_K339_E0.9491.00
115_V150_I0.9491.00
15_Q71_T0.9471.00
159_F217_L0.9461.00
77_R199_G0.9431.00
21_L45_M0.9421.00
27_G61_K0.9411.00
245_G305_T0.9381.00
208_D212_Q0.9351.00
308_D311_R0.9301.00
331_K338_A0.9181.00
232_R339_E0.9131.00
209_Y212_Q0.9131.00
192_T216_F0.9101.00
33_R59_K0.9101.00
182_D215_A0.9081.00
44_N51_V0.9071.00
235_I327_L0.9071.00
69_T99_T0.9061.00
34_Q59_K0.9041.00
270_V273_P0.9031.00
255_V262_V0.9031.00
233_V330_L0.9021.00
48_R106_K0.8991.00
252_P299_V0.8971.00
42_L89_I0.8971.00
177_A201_V0.8961.00
252_P302_E0.8951.00
44_N91_D0.8931.00
318_A326_I0.8901.00
11_V75_F0.8901.00
96_R237_E0.8871.00
59_K91_D0.8871.00
336_L340_L0.8861.00
268_P283_V0.8771.00
244_M327_L0.8761.00
68_V84_V0.8741.00
246_G252_P0.8661.00
165_L203_V0.8631.00
96_R321_R0.8611.00
318_A323_L0.8611.00
34_Q91_D0.8611.00
184_I203_V0.8591.00
168_N199_G0.8561.00
235_I340_L0.8551.00
4_D231_A0.8501.00
144_R332_A0.8501.00
2_I225_V0.8491.00
185_N192_T0.8481.00
174_F198_A0.8481.00
179_R182_D0.8481.00
178_S214_V0.8481.00
73_P82_I0.8481.00
250_I309_L0.8471.00
82_I151_V0.8461.00
183_A186_A0.8451.00
33_R61_K0.8441.00
15_Q150_I0.8360.99
327_L330_L0.8360.99
128_S288_I0.8340.99
81_R150_I0.8320.99
252_P301_P0.8320.99
168_N200_T0.8310.99
187_A223_L0.8290.99
38_T41_S0.8280.99
15_Q102_M0.8280.99
325_A328_Q0.8260.99
126_G134_S0.8250.99
39_V60_L0.8230.99
209_Y219_R0.8180.99
31_S61_K0.8170.99
31_S93_K0.8100.99
39_V42_L0.8090.99
30_D64_A0.8070.99
123_G237_E0.8060.99
38_T63_V0.8040.99
65_A117_Q0.8020.99
30_D90_G0.8010.99
19_Y38_T0.8000.99
43_A55_P0.8000.99
144_R328_Q0.7990.99
42_L45_M0.7980.99
132_G285_R0.7940.99
81_R147_N0.7920.99
17_V49_L0.7880.99
265_T287_D0.7870.99
77_R168_N0.7820.99
11_V14_N0.7810.99
173_D221_E0.7810.99
125_F138_N0.7810.99
241_T245_G0.7790.99
306_L327_L0.7730.99
270_V280_T0.7730.99
233_V340_L0.7730.99
245_G306_L0.7720.99
273_P278_G0.7690.99
16_L72_L0.7690.99
330_L333_A0.7680.99
297_L309_L0.7680.99
163_G204_R0.7670.99
276_F280_T0.7590.99
185_N191_G0.7530.99
37_F65_A0.7530.99
32_T60_L0.7470.99
194_R204_R0.7460.99
254_A297_L0.7410.99
281_V284_P0.7410.99
266_E285_R0.7380.99
246_G307_Q0.7370.99
273_P277_S0.7370.99
63_V89_I0.7340.99
259_N322_D0.7330.99
256_A320_P0.7300.99
325_A329_A0.7290.99
64_A90_G0.7240.99
142_V238_R0.7230.99
31_S54_P0.7220.99
131_G284_P0.7220.99
125_F245_G0.7210.99
128_S134_S0.7180.98
171_N337_Q0.7150.98
272_Q276_F0.7140.98
96_R122_V0.7140.98
309_L318_A0.7130.98
327_L340_L0.7120.98
88_S92_A0.7110.98
86_V142_V0.7100.98
275_P278_G0.7090.98
271_S278_G0.7070.98
24_G29_G0.7030.98
173_D176_T0.7000.98
253_V335_A0.6950.98
126_G136_T0.6950.98
43_A53_V0.6930.98
45_M67_M0.6900.98
254_A310_V0.6900.98
272_Q277_S0.6890.98
20_G24_G0.6880.98
207_A210_P0.6850.98
135_V263_T0.6830.98
282_V285_R0.6820.98
330_L336_L0.6810.98
96_R137_K0.6810.98
133_S288_I0.6780.98
106_K112_V0.6770.98
295_G319_T0.6760.98
71_T74_P0.6750.98
41_S45_M0.6730.98
205_V209_Y0.6720.98
8_V203_V0.6690.98
123_G239_T0.6690.98
45_M49_L0.6680.98
177_A214_V0.6680.98
43_A58_L0.6670.98
178_S218_A0.6670.98
170_R339_E0.6660.98
25_L29_G0.6650.97
72_L75_F0.6630.97
254_A306_L0.6620.97
303_G309_L0.6620.97
132_G286_T0.6610.97
263_T289_E0.6610.97
334_G338_A0.6580.97
31_S36_P0.6580.97
276_F279_Q0.6580.97
222_N228_D0.6570.97
174_F214_V0.6570.97
125_F321_R0.6550.97
311_R315_A0.6540.97
178_S219_R0.6510.97
72_L82_I0.6510.97
31_S35_T0.6500.97
60_L91_D0.6470.97
320_P323_L0.6460.97
85_T119_P0.6460.97
244_M248_V0.6460.97
204_R207_A0.6420.97
187_A190_P0.6420.97
270_V282_V0.6420.97
122_V143_G0.6420.97
37_F63_V0.6410.97
270_V281_V0.6410.97
164_S204_R0.6410.97
86_V145_I0.6390.97
15_Q115_V0.6380.97
205_V216_F0.6380.97
216_F220_I0.6380.97
122_V125_F0.6350.97
96_R124_G0.6340.97
121_S139_H0.6330.97
304_A308_D0.6320.97
159_F198_A0.6320.97
127_A288_I0.6300.97
32_T59_K0.6300.97
191_G204_R0.6290.96
271_S279_Q0.6290.96
166_R196_L0.6270.96
12_R15_Q0.6270.96
106_K111_Q0.6270.96
12_R107_G0.6260.96
37_F51_V0.6230.96
53_V58_L0.6230.96
67_M89_I0.6230.96
309_L313_L0.6220.96
169_L180_I0.6190.96
2_I167_L0.6170.96
305_T309_L0.6170.96
331_K340_L0.6170.96
39_V55_P0.6160.96
281_V285_R0.6150.96
9_E168_N0.6140.96
175_T228_D0.6140.96
41_S51_V0.6130.96
91_D141_T0.6120.96
163_G210_P0.6110.96
10_G14_N0.6110.96
65_A69_T0.6100.96
291_E294_K0.6100.96
299_V307_Q0.6100.96
188_F220_I0.6090.96
41_S44_N0.6090.96
237_E255_V0.6090.96
261_T296_R0.6090.96
128_S133_S0.6070.96
23_V101_L0.6060.96
231_A338_A0.6060.96
42_L63_V0.6050.96
257_H325_A0.6040.96
122_V126_G0.6030.96
115_V149_A0.6020.96
107_G111_Q0.6010.95
39_V58_L0.6000.95
122_V237_E0.5970.95
18_G24_G0.5970.95
113_Y153_R0.5970.95
314_N320_P0.5960.95
80_Q199_G0.5960.95
130_G134_S0.5940.95
257_H322_D0.5930.95
305_T308_D0.5930.95
227_P230_P0.5910.95
298_F301_P0.5880.95
104_P115_V0.5870.95
12_R149_A0.5870.95
180_I183_A0.5860.95
38_T65_A0.5840.95
279_Q282_V0.5840.95
14_N82_I0.5820.95
69_T117_Q0.5810.95
132_G266_E0.5810.95
172_P177_A0.5750.94
224_E227_P0.5740.94
130_G266_E0.5740.94
188_F223_L0.5720.94
19_Y67_M0.5700.94
273_P276_F0.5700.94
84_V145_I0.5680.94
181_A201_V0.5670.94
250_I304_A0.5670.94
317_G323_L0.5660.94
26_N141_T0.5660.94
137_K237_E0.5650.94
126_G321_R0.5650.94
26_N96_R0.5640.94
287_D290_V0.5630.94
239_T257_H0.5620.94
242_I245_G0.5610.94
36_P91_D0.5590.93
75_F174_F0.5590.93
242_I310_V0.5580.93
322_D326_I0.5580.93
335_A339_E0.5550.93
83_D144_R0.5530.93
17_V41_S0.5520.93
205_V210_P0.5510.93
32_T35_T0.5500.93
215_A218_A0.5500.93
28_T92_A0.5490.93
183_A187_A0.5460.93
299_V310_V0.5460.93
80_Q237_E0.5450.93
157_F162_G0.5450.93
127_A134_S0.5440.92
139_H237_E0.5420.92
12_R115_V0.5420.92
229_A247_D0.5390.92
121_S146_P0.5390.92
20_G29_G0.5390.92
179_R226_E0.5380.92
41_S46_L0.5380.92
246_G254_A0.5380.92
127_A130_G0.5370.92
3_K176_T0.5350.92
35_T39_V0.5350.92
6_A203_V0.5340.92
107_G115_V0.5330.92
278_G281_V0.5330.92
236_N328_Q0.5330.92
82_I149_A0.5320.92
123_G325_A0.5320.92
252_P306_L0.5320.92
31_S40_Q0.5300.91
132_G284_P0.5290.91
25_L28_T0.5290.91
330_L337_Q0.5280.91
242_I324_I0.5270.91
14_N113_Y0.5270.91
255_V330_L0.5270.91
252_P259_N0.5270.91
96_R136_T0.5260.91
306_L314_N0.5250.91
19_Y37_F0.5220.91
31_S39_V0.5210.91
173_D228_D0.5210.91
203_V217_L0.5200.91
102_M150_I0.5190.91
17_V102_M0.5190.91
194_R212_Q0.5180.91
74_P157_F0.5150.90
330_L335_A0.5140.90
233_V337_Q0.5130.90
194_R211_G0.5130.90
125_F140_P0.5110.90
209_Y216_F0.5110.90
256_A314_N0.5100.90
133_S263_T0.5100.90
34_Q37_F0.5090.90
234_V245_G0.5070.90
60_L89_I0.5060.89
297_L320_P0.5040.89
120_L145_I0.5040.89
158_D162_G0.5040.89
234_V341_E0.5030.89
31_S60_L0.5010.89
37_F41_S0.5000.89
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1nhaA 1 0.1637 10.5 0.976 Contact Map
3dptA 2 0.1754 9.5 0.977 Contact Map
3smaA 2 0.1374 9.2 0.977 Contact Map
2zf9A 1 0.3158 6.7 0.978 Contact Map
2pfuA 1 0.2251 6.5 0.979 Contact Map
2xvcA 1 0.1637 6.4 0.979 Contact Map
2pmyA 4 0.1667 6.4 0.979 Contact Map
2i7aA 2 0.1374 5.7 0.979 Contact Map
4y66B 1 0.1696 5.6 0.979 Contact Map
2jwkA 2 0.1725 5.4 0.979 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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