GREMLIN Database
FlgH - Flagellar L-ring protein
PFAM: PF02107 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 166 (165)
Sequences: 12314 (7841)
Seq/√Len: 610.4
META: 0.869

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
46_S68_D2.9151.00
89_E97_V2.8781.00
95_N118_I2.8181.00
50_S64_S2.7431.00
120_R123_D2.5931.00
103_E110_K2.3541.00
119_V135_I2.3431.00
32_V129_T2.2851.00
131_L134_R2.2601.00
29_L85_A2.2091.00
54_S60_S2.1011.00
154_P162_D2.0891.00
20_R122_E2.0661.00
105_R110_K2.0641.00
87_V96_L2.0021.00
115_L135_I1.9961.00
48_S66_S1.9931.00
32_V82_T1.9671.00
125_S129_T1.9671.00
48_S70_K1.9581.00
52_S66_S1.9501.00
44_S74_S1.9221.00
101_E114_R1.9141.00
116_S139_R1.8401.00
119_V130_V1.8111.00
85_A100_G1.7991.00
42_S76_S1.7871.00
46_S70_K1.7471.00
91_L97_V1.7361.00
99_E116_S1.7301.00
34_V131_L1.7241.00
50_S66_S1.6911.00
33_I81_G1.6891.00
98_I135_I1.6821.00
98_I119_V1.6761.00
48_S68_D1.6671.00
46_S72_S1.6291.00
103_E139_R1.6251.00
44_S70_K1.5821.00
29_L119_V1.5271.00
3_A8_Q1.4701.00
44_S72_S1.4631.00
36_S78_S1.4441.00
45_T152_Q1.4401.00
42_S72_S1.4191.00
86_T137_D1.3881.00
88_V99_E1.3771.00
26_G86_T1.3651.00
15_S18_E1.3651.00
35_E102_K1.3631.00
30_T84_T1.3531.00
40_S78_S1.3361.00
153_R159_R1.3271.00
40_S74_S1.3141.00
50_S68_D1.3091.00
161_F165_W1.3071.00
120_R128_N1.2981.00
97_V118_I1.2981.00
82_T133_T1.2861.00
99_E114_R1.2821.00
31_V85_A1.2811.00
54_S64_S1.2801.00
42_S74_S1.2631.00
147_V154_P1.2551.00
101_E112_E1.2441.00
32_V131_L1.2411.00
53_V61_A1.1911.00
52_S64_S1.1841.00
75_R109_E1.1831.00
85_A98_I1.1821.00
114_R141_E1.1631.00
32_V125_S1.1571.00
28_I84_T1.1471.00
91_L118_I1.1161.00
147_V150_D1.1151.00
43_A148_I1.1041.00
108_Q147_V1.1001.00
52_S62_S1.0831.00
35_E104_V1.0801.00
110_K145_R1.0741.00
45_T147_V1.0681.00
105_R141_E1.0581.00
25_V89_E1.0541.00
123_D130_V1.0301.00
38_S76_S1.0291.00
51_S158_T1.0261.00
100_G115_L1.0221.00
29_L124_I1.0091.00
108_Q153_R1.0061.00
125_S134_R1.0051.00
82_T129_T1.0051.00
19_D22_A1.0021.00
41_K77_N0.9851.00
103_E112_E0.9851.00
71_G148_I0.9841.00
91_L95_N0.9761.00
45_T73_T0.9731.00
34_V80_T0.9731.00
34_V133_T0.9711.00
69_G146_G0.9611.00
151_A162_D0.9251.00
28_I95_N0.9211.00
81_G113_I0.9001.00
118_I137_D0.8951.00
8_Q11_S0.8931.00
154_P158_T0.8871.00
123_D134_R0.8821.00
105_R143_G0.8791.00
53_V65_S0.8791.00
10_G13_Y0.8781.00
38_S78_S0.8741.00
37_T81_G0.8721.00
40_S76_S0.8711.00
71_G146_G0.8671.00
55_P58_L0.8551.00
81_G132_S0.8471.00
28_I136_A0.8441.00
31_V98_I0.8401.00
88_V97_V0.8241.00
150_D159_R0.8201.00
41_K109_E0.8121.00
156_W160_F0.8081.00
57_L60_S0.8081.00
41_K79_L0.8061.00
91_L96_L0.8051.00
123_D128_N0.7971.00
106_V109_E0.7871.00
47_T151_A0.7841.00
47_T154_P0.7791.00
54_S62_S0.7771.00
79_L142_Y0.7691.00
31_V115_L0.7661.00
97_V116_S0.7631.00
44_S68_D0.7591.00
90_V96_L0.7591.00
25_V90_V0.7501.00
148_I152_Q0.7461.00
85_A135_I0.7431.00
114_R143_G0.7421.00
35_E81_G0.7271.00
49_R67_F0.7271.00
150_D163_S0.7201.00
18_E23_R0.7191.00
47_T162_D0.7151.00
39_A79_L0.7131.00
107_N144_G0.7071.00
73_T152_Q0.7031.00
95_N121_P0.7021.00
39_A106_V0.6991.00
35_E132_S0.6951.00
46_S66_S0.6951.00
109_E149_A0.6951.00
82_T132_S0.6941.00
77_N142_Y0.6891.00
154_P159_R0.6881.00
82_T134_R0.6831.00
115_L138_A0.6811.00
65_S151_A0.6811.00
73_T107_N0.6781.00
130_V134_R0.6731.00
150_D154_P0.6731.00
29_L98_I0.6721.00
14_R18_E0.6711.00
108_Q149_A0.6661.00
77_N149_A0.6641.00
37_T111_Q0.6601.00
68_D72_S0.6591.00
33_I37_T0.6571.00
71_G151_A0.6561.00
121_P124_I0.6451.00
38_S80_T0.6371.00
47_T147_V0.6341.00
45_T69_G0.6331.00
9_A12_R0.6321.00
94_G121_P0.6311.00
36_S80_T0.6201.00
155_G158_T0.6181.00
45_T148_I0.6151.00
43_A75_R0.6131.00
77_N144_G0.6121.00
41_K106_V0.6121.00
86_T136_A0.6091.00
159_R163_S0.6091.00
41_K75_R0.6081.00
132_S140_I0.6031.00
158_T162_D0.6011.00
32_V127_D0.5981.00
77_N111_Q0.5971.00
31_V135_I0.5951.00
47_T71_G0.5871.00
73_T108_Q0.5841.00
156_W163_S0.5831.00
102_K138_A0.5811.00
28_I123_D0.5781.00
155_G159_R0.5771.00
50_S62_S0.5761.00
26_G100_G0.5761.00
86_T118_I0.5721.00
129_T134_R0.5691.00
43_A152_Q0.5681.00
75_R107_N0.5651.00
84_T136_A0.5631.00
41_K73_T0.5621.00
139_R143_G0.5611.00
51_S65_S0.5611.00
112_E141_E0.5591.00
84_T128_N0.5531.00
11_S15_S0.5521.00
157_L161_F0.5490.99
86_T95_N0.5490.99
37_T142_Y0.5460.99
111_Q142_Y0.5450.99
148_I151_A0.5450.99
33_I132_S0.5420.99
155_G165_W0.5400.99
40_S72_S0.5390.99
16_L20_R0.5390.99
37_T113_I0.5360.99
125_S131_L0.5340.99
31_V119_V0.5340.99
51_S61_A0.5290.99
12_R15_S0.5280.99
147_V159_R0.5280.99
102_K134_R0.5260.99
51_S63_S0.5250.99
147_V153_R0.5240.99
147_V152_Q0.5180.99
96_L124_I0.5180.99
83_I102_K0.5180.99
37_T104_V0.5170.99
146_G149_A0.5170.99
42_S46_S0.5160.99
106_V111_Q0.5140.99
144_G149_A0.5140.99
112_E145_R0.5130.99
22_A29_L0.5120.99
102_K113_I0.5110.99
39_A142_Y0.5100.99
30_T128_N0.5090.99
22_A87_V0.5090.99
51_S67_F0.5060.99
158_T163_S0.5050.99
65_S162_D0.5040.99
33_I107_N0.5030.99
96_L121_P0.5020.99
77_N81_G0.5020.99
20_R23_R0.5010.99
39_A73_T0.5000.99
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2dgyA 1 0.5422 19.9 0.928 Contact Map
3tiwA 1 0.3614 14.2 0.933 Contact Map
3bdlA 2 0.5 8.7 0.939 Contact Map
4toiA 2 0.4458 6.3 0.943 Contact Map
4ql5A 4 0.3976 5 0.946 Contact Map
1gmeA 6 0.7048 4.6 0.947 Contact Map
3wbkC 1 0.006 4.6 0.947 Contact Map
2d9rA 1 0.2108 4.3 0.948 Contact Map
1hr0W 1 0.3916 3.7 0.949 Contact Map
1ah9A 1 0.3916 3.6 0.949 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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