TctA - PFAM28P - GREMLIN Contacts

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TctA - Tripartite tricarboxylate transporter TctA family

PFAM:	PF01970	Sequences: LLLLLLGVLLGTLVGALPGLGPTMAIALLLPLTFGMDPVSALIMLAGIYYGAMYGGSITAILLNIPGTPASAATTLDGYPMAKQGRAGRALGIAAIGSFIGGLIGTLLLILLAPPLAEVALKFGPPEYFALMLLGLTLIASLSGGSLLKGLIAGLLGLLLGTVGLDPITGVPRFTFGIPELLDGIDLVPVLIGLFAISEILRNLEEGGKIPPTRKDLKRSWPPILRGSLIGFFIGILPGAGATIASFLSYAVAKRLSKHPEKFGKGAIEGVAAPEAANNAAAGGALIPLLTLGIPGSATTAVLLGALMIHGIQPGPLLFTENPDLVWGLIASMLIANVLLLILNLPLIRLFVKLLRIPYRILYPIILVFCVIGAYAVNNSVFDVWVMLVFGVLGYLMRKLGFPLAPLVL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_10
Length:	409 (409)
Sequences:	17118 (10151)
Seq/√Len:	501.9
META:	0.81

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
86_R	89_R	4.906	1.00
262_K	267_A	4.512	1.00
353_K	356_R	4.220	1.00
259_H	262_K	3.924	1.00
93_I	268_I	3.187	1.00
89_R	216_D	2.974	1.00
378_N	383_D	2.901	1.00
81_M	268_I	2.887	1.00
205_E	399_K	2.881	1.00
80_P	83_K	2.777	1.00
99_F	341_L	2.688	1.00
93_I	272_A	2.633	1.00
218_K	221_W	2.558	1.00
64_N	75_T	2.515	1.00
108_L	232_F	2.513	1.00
101_G	276_A	2.489	1.00
262_K	265_K	2.451	1.00
102_G	337_N	2.418	1.00
252_V	255_R	2.412	1.00
215_K	219_R	2.411	1.00
215_K	218_K	2.406	1.00
317_L	321_E	2.368	1.00
230_I	252_V	2.341	1.00
202_R	398_R	2.302	1.00
259_H	267_A	2.242	1.00
61_I	78_G	2.237	1.00
223_P	227_G	2.229	1.00
97_G	276_A	2.217	1.00
43_I	332_S	2.212	1.00
160_L	407_L	2.199	1.00
180_E	382_F	2.167	1.00
3_L	40_S	2.162	1.00
198_S	202_R	2.159	1.00
26_I	299_T	2.151	1.00
403_P	406_P	2.061	1.00
205_E	395_Y	2.044	1.00
103_L	334_L	2.024	1.00
381_V	384_V	2.023	1.00
84_Q	262_K	2.007	1.00
110_I	334_L	1.950	1.00
249_S	273_A	1.947	1.00
37_D	40_S	1.944	1.00
219_R	269_E	1.937	1.00
124_G	127_E	1.904	1.00
104_I	108_L	1.901	1.00
221_W	225_L	1.901	1.00
100_I	224_I	1.895	1.00
381_V	385_W	1.881	1.00
104_I	232_F	1.861	1.00
229_L	233_F	1.860	1.00
214_R	218_K	1.844	1.00
197_I	367_L	1.841	1.00
220_S	272_A	1.828	1.00
222_P	226_R	1.765	1.00
226_R	256_L	1.764	1.00
226_R	253_A	1.762	1.00
178_I	182_L	1.745	1.00
39_V	328_G	1.726	1.00
225_L	229_L	1.721	1.00
33_T	310_H	1.721	1.00
64_N	80_P	1.715	1.00
317_L	320_T	1.706	1.00
385_W	389_V	1.706	1.00
252_V	256_L	1.685	1.00
57_S	61_I	1.674	1.00
185_I	190_V	1.669	1.00
82_A	87_A	1.658	1.00
74_T	271_V	1.654	1.00
220_S	223_P	1.651	1.00
139_I	154_G	1.649	1.00
156_L	407_L	1.634	1.00
79_Y	83_K	1.628	1.00
98_S	278_N	1.620	1.00
92_G	212_P	1.612	1.00
118_E	122_K	1.608	1.00
389_V	393_L	1.592	1.00
186_D	189_P	1.575	1.00
200_I	363_Y	1.526	1.00
153_A	397_M	1.525	1.00
257_S	269_E	1.524	1.00
72_A	247_F	1.519	1.00
104_I	228_S	1.511	1.00
253_A	263_F	1.509	1.00
153_A	407_L	1.506	1.00
397_M	402_F	1.500	1.00
185_I	386_V	1.494	1.00
143_S	150_G	1.489	1.00
64_N	398_R	1.467	1.00
297_S	300_T	1.465	1.00
257_S	261_E	1.463	1.00
22_P	52_A	1.460	1.00
371_V	387_M	1.454	1.00
5_L	339_L	1.453	1.00
189_P	386_V	1.450	1.00
13_L	17_L	1.442	1.00
213_T	216_D	1.437	1.00
119_V	122_K	1.436	1.00
374_A	387_M	1.436	1.00
112_L	115_P	1.435	1.00
223_P	253_A	1.435	1.00
240_A	244_I	1.404	1.00
84_Q	265_K	1.398	1.00
396_L	400_L	1.396	1.00
110_I	330_I	1.389	1.00
397_M	407_L	1.386	1.00
227_G	276_A	1.380	1.00
190_V	390_F	1.378	1.00
14_V	25_A	1.374	1.00
232_F	284_G	1.367	1.00
76_L	80_P	1.360	1.00
145_G	401_G	1.356	1.00
4_L	47_G	1.356	1.00
93_I	220_S	1.339	1.00
163_V	185_I	1.332	1.00
197_I	387_M	1.330	1.00
319_F	326_V	1.329	1.00
105_G	283_G	1.328	1.00
57_S	94_A	1.324	1.00
14_V	20_L	1.319	1.00
51_G	55_G	1.317	1.00
81_M	84_Q	1.309	1.00
103_L	107_L	1.306	1.00
289_L	304_L	1.303	1.00
245_A	281_A	1.300	1.00
172_P	175_T	1.289	1.00
160_L	185_I	1.285	1.00
79_Y	82_A	1.274	1.00
43_I	47_G	1.274	1.00
338_V	342_I	1.266	1.00
100_I	104_I	1.263	1.00
390_F	394_G	1.261	1.00
108_L	112_L	1.259	1.00
285_A	297_S	1.247	1.00
115_P	119_V	1.242	1.00
382_F	385_W	1.241	1.00
220_S	269_E	1.240	1.00
360_R	364_P	1.239	1.00
199_E	203_N	1.230	1.00
7_G	44_M	1.227	1.00
172_P	182_L	1.227	1.00
393_L	397_M	1.224	1.00
361_I	365_I	1.213	1.00
371_V	384_V	1.205	1.00
262_K	269_E	1.201	1.00
53_M	70_A	1.201	1.00
97_G	224_I	1.200	1.00
347_L	351_F	1.193	1.00
16_A	59_T	1.192	1.00
113_A	291_T	1.184	1.00
88_G	92_G	1.161	1.00
348_I	352_V	1.155	1.00
318_L	326_V	1.152	1.00
392_V	396_L	1.143	1.00
25_A	48_I	1.129	1.00
54_Y	344_N	1.123	1.00
233_F	237_L	1.122	1.00
197_I	391_G	1.121	1.00
4_L	43_I	1.120	1.00
76_L	247_F	1.120	1.00
194_L	407_L	1.118	1.00
9_L	343_L	1.118	1.00
8_V	47_G	1.113	1.00
148_L	152_I	1.109	1.00
194_L	394_G	1.106	1.00
159_L	163_V	1.104	1.00
156_L	393_L	1.103	1.00
2_L	6_L	1.097	1.00
200_I	367_L	1.096	1.00
106_T	334_L	1.089	1.00
136_L	154_G	1.087	1.00
226_R	252_V	1.083	1.00
398_R	404_L	1.082	1.00
221_W	224_I	1.082	1.00
223_P	226_R	1.080	1.00
151_L	155_L	1.079	1.00
74_T	275_E	1.079	1.00
203_N	363_Y	1.072	1.00
202_R	205_E	1.068	1.00
219_R	262_K	1.067	1.00
349_R	353_K	1.066	1.00
149_K	402_F	1.063	1.00
253_A	273_A	1.063	1.00
312_I	318_L	1.062	1.00
153_A	402_F	1.059	1.00
93_I	97_G	1.056	1.00
342_I	346_P	1.052	1.00
179_P	182_L	1.051	1.00
371_V	388_L	1.050	1.00
397_M	404_L	1.047	1.00
193_G	390_F	1.044	1.00
257_S	267_A	1.043	1.00
46_A	329_L	1.034	1.00
197_I	201_L	1.032	1.00
222_P	225_L	1.030	1.00
322_N	325_L	1.030	1.00
106_T	333_M	1.029	1.00
73_A	76_L	1.029	1.00
227_G	252_V	1.026	1.00
180_E	380_S	1.026	1.00
51_G	340_L	1.025	1.00
91_L	348_I	1.024	1.00
216_D	219_R	1.023	1.00
98_S	279_N	1.023	1.00
257_S	260_P	1.023	1.00
106_T	110_I	1.022	1.00
234_I	248_L	1.020	1.00
382_F	386_V	1.020	1.00
223_P	269_E	1.019	1.00
95_A	344_N	1.011	1.00
214_R	217_L	1.010	1.00
334_L	338_V	1.008	1.00
77_D	271_V	1.005	1.00
68_T	71_S	1.003	1.00
152_I	402_F	1.002	1.00
3_L	6_L	1.002	1.00
350_L	353_K	1.000	1.00
186_D	383_D	0.996	1.00
93_I	271_V	0.996	1.00
47_G	51_G	0.991	1.00
347_L	350_L	0.987	1.00
116_L	236_I	0.982	1.00
89_R	213_T	0.981	1.00
249_S	277_A	0.980	1.00
166_D	169_T	0.980	1.00
196_A	370_C	0.968	1.00
218_K	222_P	0.967	1.00
199_E	202_R	0.967	1.00
45_L	303_L	0.962	1.00
253_A	256_L	0.959	1.00
192_I	370_C	0.956	1.00
29_L	48_I	0.955	1.00
199_E	398_R	0.951	1.00
234_I	245_A	0.944	1.00
186_D	378_N	0.940	1.00
259_H	265_K	0.938	1.00
64_N	83_K	0.937	1.00
5_L	343_L	0.934	1.00
385_W	388_L	0.931	1.00
11_G	15_G	0.929	1.00
132_M	135_G	0.928	1.00
406_P	409_L	0.924	1.00
54_Y	57_S	0.924	1.00
352_V	355_L	0.923	1.00
56_G	68_T	0.923	1.00
89_R	268_I	0.922	1.00
213_T	218_K	0.922	1.00
203_N	359_Y	0.921	1.00
228_S	276_A	0.920	1.00
308_M	314_P	0.918	1.00
191_L	408_V	0.914	1.00
73_A	247_F	0.913	1.00
12_T	51_G	0.912	1.00
23_T	27_A	0.912	1.00
165_L	172_P	0.911	1.00
81_M	267_A	0.909	1.00
386_V	389_V	0.909	1.00
249_S	252_V	0.907	1.00
104_I	229_L	0.906	1.00
240_A	297_S	0.905	1.00
156_L	160_L	0.900	1.00
290_L	312_I	0.900	1.00
257_S	262_K	0.899	1.00
185_I	389_V	0.897	1.00
323_P	326_V	0.895	1.00
213_T	217_L	0.894	1.00
313_Q	321_E	0.893	1.00
370_C	387_M	0.893	1.00
59_T	68_T	0.892	1.00
70_A	242_A	0.889	1.00
275_E	278_N	0.888	1.00
65_I	196_A	0.886	1.00
53_M	71_S	0.883	1.00
104_I	225_L	0.882	1.00
228_S	280_A	0.880	1.00
141_S	251_A	0.880	1.00
346_P	350_L	0.878	1.00
42_L	307_L	0.873	1.00
395_Y	399_K	0.873	1.00
326_V	330_I	0.873	1.00
50_Y	102_G	0.872	1.00
251_A	255_R	0.872	1.00
341_L	345_L	0.867	1.00
21_G	24_M	0.867	1.00
221_W	229_L	0.866	1.00
99_F	103_L	0.865	1.00
290_L	329_L	0.860	1.00
38_P	41_A	0.859	1.00
289_L	300_T	0.859	1.00
61_I	90_A	0.856	1.00
23_T	302_V	0.855	1.00
46_A	286_L	0.854	1.00
202_R	206_E	0.853	1.00
45_L	306_A	0.852	1.00
49_Y	299_T	0.851	1.00
285_A	300_T	0.851	1.00
159_L	174_F	0.850	1.00
41_A	310_H	0.849	1.00
260_P	267_A	0.845	1.00
96_I	341_L	0.842	1.00
242_A	281_A	0.840	1.00
386_V	390_F	0.839	1.00
227_G	249_S	0.837	1.00
24_M	28_L	0.837	1.00
61_I	94_A	0.837	1.00
8_V	339_L	0.836	1.00
198_S	404_L	0.836	1.00
81_M	90_A	0.833	1.00
140_A	147_L	0.833	1.00
3_L	44_M	0.833	1.00
159_L	162_T	0.832	1.00
303_L	307_L	0.831	1.00
257_S	265_K	0.826	1.00
192_I	374_A	0.824	1.00
113_A	319_F	0.822	1.00
323_P	328_G	0.820	1.00
57_S	275_E	0.819	1.00
4_L	8_V	0.819	1.00
89_R	93_I	0.818	1.00
202_R	399_K	0.816	1.00
54_Y	95_A	0.816	1.00
380_S	383_D	0.814	1.00
267_A	271_V	0.812	1.00
224_I	276_A	0.809	1.00
80_P	265_K	0.809	1.00
10_L	14_V	0.809	1.00
50_Y	336_A	0.808	1.00
158_L	162_T	0.804	1.00
374_A	384_V	0.801	1.00
155_L	159_L	0.798	1.00
234_I	240_A	0.796	1.00
96_I	217_L	0.793	1.00
95_A	348_I	0.788	1.00
109_L	113_A	0.786	1.00
91_L	95_A	0.785	1.00
72_A	76_L	0.784	1.00
224_I	272_A	0.783	1.00
81_M	86_R	0.781	1.00
240_A	409_L	0.779	1.00
357_I	362_L	0.778	1.00
144_G	147_L	0.775	1.00
259_H	269_E	0.773	1.00
257_S	263_F	0.770	1.00
220_S	224_I	0.769	1.00
260_P	269_E	0.768	1.00
236_I	287_I	0.768	1.00
227_G	253_A	0.767	1.00
40_S	43_I	0.766	1.00
92_G	345_L	0.763	1.00
97_G	272_A	0.762	1.00
200_I	366_I	0.761	1.00
260_P	263_F	0.761	1.00
223_P	273_A	0.758	1.00
398_R	401_G	0.758	1.00
153_A	403_P	0.757	1.00
190_V	407_L	0.756	1.00
189_P	374_A	0.754	1.00
377_V	383_D	0.751	1.00
114_P	117_A	0.749	1.00
42_L	329_L	0.743	1.00
362_L	366_I	0.741	1.00
151_L	154_G	0.741	1.00
140_A	154_G	0.740	1.00
146_S	149_K	0.740	1.00
74_T	278_N	0.740	1.00
208_G	211_P	0.738	1.00
3_L	7_G	0.738	1.00
339_L	342_I	0.737	1.00
105_G	282_A	0.737	1.00
14_V	21_G	0.736	1.00
29_L	44_M	0.734	1.00
129_F	133_L	0.734	1.00
24_M	27_A	0.734	1.00
308_M	313_Q	0.731	1.00
115_P	118_E	0.731	1.00
363_Y	367_L	0.731	1.00
50_Y	333_M	0.724	1.00
44_M	47_G	0.723	1.00
304_L	308_M	0.723	1.00
162_T	174_F	0.723	1.00
160_L	390_F	0.722	1.00
205_E	208_G	0.719	1.00
192_I	387_M	0.716	1.00
147_L	151_L	0.715	1.00
333_M	337_N	0.714	1.00
216_D	268_I	0.713	1.00
359_Y	363_Y	0.712	1.00
33_T	36_M	0.711	1.00
56_G	59_T	0.707	1.00
223_P	256_L	0.706	1.00
77_D	274_P	0.706	1.00
223_P	272_A	0.704	1.00
137_T	141_S	0.701	1.00
365_I	369_F	0.701	1.00
255_R	260_P	0.700	1.00
160_L	163_V	0.698	1.00
4_L	339_L	0.697	1.00
130_A	133_L	0.696	1.00
5_L	9_L	0.695	1.00
328_G	332_S	0.694	1.00
320_T	323_P	0.693	1.00
158_L	161_G	0.687	1.00
217_L	221_W	0.685	1.00
3_L	36_M	0.685	1.00
81_M	93_I	0.685	1.00
69_P	243_T	0.681	1.00
234_I	296_G	0.679	1.00
113_A	117_A	0.678	1.00
14_V	52_A	0.677	1.00
16_A	21_G	0.677	1.00
110_I	331_A	0.676	1.00
324_D	328_G	0.675	1.00
39_V	43_I	0.673	1.00
99_F	338_V	0.672	1.00
243_T	298_A	0.670	1.00
261_E	265_K	0.669	1.00
90_A	271_V	0.668	1.00
40_S	44_M	0.668	1.00
245_A	248_L	0.667	1.00
135_G	237_L	0.666	1.00
165_L	182_L	0.666	1.00
390_F	393_L	0.662	1.00
222_P	269_E	0.662	1.00
296_G	300_T	0.661	1.00
212_P	216_D	0.661	1.00
227_G	273_A	0.661	1.00
246_S	274_P	0.660	1.00
111_L	115_P	0.660	1.00
343_L	347_L	0.658	1.00
153_A	156_L	0.657	1.00
128_Y	132_M	0.656	1.00
81_M	89_R	0.654	1.00
340_L	344_N	0.653	1.00
50_Y	337_N	0.652	1.00
80_P	267_A	0.651	1.00
247_F	405_A	0.648	1.00
388_L	392_V	0.647	1.00
143_S	147_L	0.647	1.00
117_A	319_F	0.646	1.00
327_W	330_I	0.643	1.00
92_G	96_I	0.642	1.00
198_S	398_R	0.642	1.00
169_T	172_P	0.642	1.00
23_T	298_A	0.641	1.00
281_A	297_S	0.640	1.00
96_I	224_I	0.638	1.00
50_Y	282_A	0.638	1.00
356_R	359_Y	0.638	1.00
100_I	225_L	0.637	1.00
46_A	332_S	0.636	1.00
34_F	309_I	0.635	1.00
87_A	271_V	0.634	1.00
16_A	58_I	0.633	1.00
283_G	286_L	0.632	1.00
226_R	230_I	0.632	1.00
330_I	334_L	0.632	1.00
243_T	246_S	0.629	1.00
274_P	277_A	0.629	1.00
370_C	374_A	0.627	1.00
27_A	302_V	0.625	1.00
312_I	325_L	0.625	1.00
99_F	340_L	0.622	1.00
52_A	68_T	0.622	1.00
229_L	232_F	0.619	1.00
183_D	186_D	0.618	1.00
258_K	261_E	0.616	1.00
160_L	389_V	0.616	1.00
220_S	268_I	0.614	1.00
190_V	194_L	0.614	1.00
384_V	387_M	0.612	1.00
72_A	75_T	0.610	1.00
12_T	58_I	0.609	0.99
109_L	330_I	0.605	0.99
245_A	277_A	0.603	0.99
14_V	22_P	0.602	0.99
313_Q	322_N	0.602	0.99
260_P	265_K	0.600	0.99
116_L	291_T	0.599	0.99
58_I	61_I	0.599	0.99
150_G	154_G	0.597	0.99
198_S	201_L	0.597	0.99
189_P	383_D	0.596	0.99
103_L	106_T	0.596	0.99
143_S	154_G	0.596	0.99
4_L	336_A	0.595	0.99
279_N	340_L	0.594	0.99
42_L	303_L	0.594	0.99
143_S	403_P	0.593	0.99
106_T	283_G	0.592	0.99
116_L	119_V	0.591	0.99
147_L	150_G	0.591	0.99
175_T	178_I	0.590	0.99
120_A	316_P	0.590	0.99
94_A	271_V	0.588	0.99
80_P	84_Q	0.587	0.99
246_S	277_A	0.587	0.99
331_A	335_I	0.586	0.99
42_L	325_L	0.584	0.99
243_T	281_A	0.583	0.99
352_V	356_R	0.582	0.99
8_V	336_A	0.581	0.99
300_T	303_L	0.580	0.99
207_G	211_P	0.580	0.99
397_M	400_L	0.579	0.99
94_A	275_E	0.578	0.99
17_L	369_F	0.576	0.99
165_L	179_P	0.574	0.99
78_G	90_A	0.574	0.99
9_L	13_L	0.573	0.99
306_A	310_H	0.573	0.99
313_Q	317_L	0.573	0.99
214_R	221_W	0.573	0.99
156_L	397_M	0.572	0.99
153_A	406_P	0.571	0.99
171_V	175_T	0.571	0.99
177_G	180_E	0.571	0.99
14_V	29_L	0.570	0.99
105_G	284_G	0.569	0.99
88_G	212_P	0.567	0.99
149_K	153_A	0.566	0.99
268_I	271_V	0.565	0.99
7_G	11_G	0.565	0.99
249_S	253_A	0.565	0.99
10_L	29_L	0.564	0.99
321_E	324_D	0.563	0.99
375_Y	379_N	0.560	0.99
339_L	343_L	0.559	0.99
84_Q	267_A	0.558	0.99
402_F	406_P	0.557	0.99
163_V	181_L	0.557	0.99
137_T	154_G	0.557	0.99
20_L	24_M	0.556	0.99
96_I	100_I	0.554	0.99
241_G	296_G	0.552	0.99
41_A	309_I	0.552	0.99
96_I	345_L	0.552	0.99
134_L	137_T	0.551	0.99
6_L	10_L	0.550	0.99
268_I	272_A	0.548	0.99
70_A	243_T	0.548	0.99
302_V	305_G	0.545	0.99
43_I	46_A	0.545	0.99
298_A	308_M	0.545	0.99
22_P	299_T	0.543	0.99
53_M	282_A	0.543	0.99
290_L	297_S	0.543	0.99
216_D	220_S	0.542	0.99
358_P	361_I	0.540	0.99
53_M	279_N	0.540	0.99
180_E	386_V	0.539	0.99
224_I	228_S	0.539	0.99
332_S	336_A	0.538	0.99
195_F	391_G	0.538	0.99
62_L	88_G	0.538	0.99
144_G	403_P	0.537	0.99
201_L	395_Y	0.537	0.99
212_P	217_L	0.536	0.99
375_Y	384_V	0.536	0.99
39_V	324_D	0.536	0.99
240_A	246_S	0.535	0.99
78_G	271_V	0.534	0.99
10_L	44_M	0.533	0.99
276_A	280_A	0.531	0.99
78_G	87_A	0.530	0.99
367_L	371_V	0.530	0.99
89_R	220_S	0.529	0.99
194_L	390_F	0.529	0.99
145_G	149_K	0.528	0.99
289_L	307_L	0.528	0.99
46_A	303_L	0.527	0.99
23_T	299_T	0.527	0.99
22_P	53_M	0.527	0.99
14_V	17_L	0.527	0.99
319_F	330_I	0.525	0.99
153_A	393_L	0.524	0.98
86_R	268_I	0.524	0.98
149_K	400_L	0.522	0.98
153_A	161_G	0.522	0.98
172_P	176_F	0.521	0.98
235_G	288_P	0.521	0.98
258_K	262_K	0.519	0.98
2_L	5_L	0.517	0.98
89_R	212_P	0.516	0.98
123_F	127_E	0.516	0.98
10_L	25_A	0.514	0.98
253_A	269_E	0.514	0.98
141_S	147_L	0.513	0.98
93_I	224_I	0.513	0.98
240_A	296_G	0.513	0.98
84_Q	89_R	0.511	0.98
135_G	244_I	0.511	0.98
154_G	158_L	0.511	0.98
197_I	370_C	0.511	0.98
318_L	322_N	0.510	0.98
186_D	190_V	0.510	0.98
261_E	267_A	0.508	0.98
318_L	323_P	0.506	0.98
12_T	343_L	0.505	0.98
322_N	326_V	0.505	0.98
226_R	255_R	0.505	0.98
128_Y	131_L	0.505	0.98
109_L	283_G	0.504	0.98
240_A	245_A	0.504	0.98
15_G	18_P	0.503	0.98
120_A	292_L	0.503	0.98
175_T	179_P	0.503	0.98
214_R	225_L	0.503	0.98
42_L	312_I	0.503	0.98
228_S	232_F	0.502	0.98
8_V	340_L	0.502	0.98
57_S	274_P	0.501	0.98
6_L	44_M	0.501	0.98
266_G	270_G	0.501	0.98
53_M	242_A	0.500	0.98
31_P	34_F	0.500	0.98

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3nd0A	2	0.5941	16.8	0.968	Contact Map
4cz8A	2	0.6284	16.2	0.968	Contact Map
4czbA	2	0.5892	15.3	0.969	Contact Map
3orgA	2	0.5208	9.6	0.971	Contact Map
2ksfA	1	0.2616	9.2	0.972	Contact Map
4bwzA	2	0.5795	8.5	0.972	Contact Map
2jwaA	2	0.1076	4.8	0.975	Contact Map
4xnjA	1	0.198	4.6	0.975	Contact Map
4eneA	2	0.6284	4.2	0.976	Contact Map
4tphA	2	0.1883	2.5	0.978	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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