DDE_Tnp_ISL3 - PFAM28P - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

DDE_Tnp_ISL3 - Transposase

PFAM:	PF01610	Sequences: IGIDEISLRKGHRYLTVVVDLDADTGRVLWVGEGRSKETLEAFFERLGEERRAKIEAVAMDMSPAYIKAVREHLPNAVIVFDRFHVVKLLNEALDEVRRREQRELRGEKRKLLKGSRWLLLKNPENLTEKQRERLEELLRLNPKLARAYLLKEELRQLWDYKSPAWARRFLDRWIAWARRSRLPPFKKLARTLRRHRDGILNYFDHRITNGFVEGLNNKIKVIKRRAYGFRNFENFRLRI	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_10
Length:	240 (237)
Sequences:	26090 (15172)
Seq/√Len:	985.6
META:	0.945

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
37_K	68_K	3.241	1.00
88_K	92_E	3.232	1.00
60_M	79_I	2.984	1.00
164_P	205_D	2.747	1.00
163_S	166_W	2.569	1.00
89_L	192_T	2.546	1.00
154_E	177_W	2.484	1.00
90_L	189_L	2.425	1.00
172_D	197_R	2.374	1.00
45_E	73_H	2.304	1.00
41_E	73_H	2.271	1.00
58_V	70_V	2.263	1.00
179_R	194_R	2.208	1.00
48_G	51_R	2.168	1.00
34_G	39_T	2.152	1.00
62_M	81_F	2.080	1.00
97_V	148_A	1.993	1.00
48_G	52_R	1.986	1.00
100_R	185_P	1.981	1.00
227_A	230_F	1.954	1.00
81_F	199_G	1.954	1.00
57_A	208_I	1.948	1.00
3_I	40_L	1.929	1.00
123_N	156_R	1.913	1.00
41_E	72_E	1.910	1.00
19_V	213_V	1.846	1.00
168_R	197_R	1.826	1.00
176_A	180_R	1.825	1.00
41_E	69_A	1.819	1.00
232_N	235_N	1.773	1.00
55_I	74_L	1.753	1.00
90_L	155_L	1.744	1.00
146_A	150_L	1.738	1.00
96_E	99_R	1.719	1.00
101_E	144_K	1.699	1.00
60_M	70_V	1.679	1.00
37_K	72_E	1.676	1.00
221_K	224_K	1.665	1.00
36_S	39_T	1.624	1.00
67_I	81_F	1.603	1.00
175_I	194_R	1.584	1.00
84_F	88_K	1.577	1.00
233_F	237_R	1.561	1.00
161_Y	170_F	1.555	1.00
101_E	104_E	1.540	1.00
218_N	225_R	1.535	1.00
2_G	21_L	1.531	1.00
83_R	87_V	1.530	1.00
219_K	228_Y	1.527	1.00
222_V	228_Y	1.526	1.00
164_P	168_R	1.520	1.00
117_R	121_L	1.508	1.00
199_G	202_N	1.492	1.00
49_E	53_A	1.489	1.00
44_F	70_V	1.477	1.00
123_N	126_N	1.473	1.00
215_G	218_N	1.473	1.00
69_A	73_H	1.472	1.00
20_D	25_T	1.467	1.00
2_G	213_V	1.455	1.00
67_I	71_R	1.452	1.00
6_I	221_K	1.442	1.00
17_V	220_I	1.438	1.00
78_V	205_D	1.428	1.00
95_D	99_R	1.414	1.00
158_L	170_F	1.408	1.00
128_T	131_Q	1.402	1.00
116_S	120_L	1.396	1.00
161_Y	166_W	1.386	1.00
122_K	131_Q	1.384	1.00
68_K	72_E	1.381	1.00
174_W	178_A	1.363	1.00
222_V	225_R	1.349	1.00
100_R	144_K	1.330	1.00
97_V	185_P	1.329	1.00
218_N	228_Y	1.307	1.00
57_A	206_H	1.307	1.00
59_A	208_I	1.287	1.00
7_S	11_G	1.284	1.00
51_R	54_K	1.283	1.00
179_R	191_R	1.273	1.00
59_A	210_N	1.269	1.00
210_N	213_V	1.244	1.00
41_E	45_E	1.243	1.00
127_L	135_L	1.242	1.00
19_V	216_L	1.236	1.00
178_A	186_F	1.232	1.00
184_P	187_K	1.216	1.00
78_V	202_N	1.201	1.00
165_A	169_R	1.199	1.00
57_A	80_V	1.199	1.00
18_V	43_F	1.198	1.00
175_I	179_R	1.197	1.00
67_I	199_G	1.195	1.00
37_K	41_E	1.171	1.00
175_I	190_A	1.168	1.00
92_E	96_E	1.168	1.00
87_V	156_R	1.165	1.00
179_R	187_K	1.150	1.00
52_R	73_H	1.148	1.00
60_M	67_I	1.148	1.00
197_R	201_L	1.146	1.00
35_R	63_S	1.144	1.00
168_R	201_L	1.132	1.00
16_T	20_D	1.128	1.00
151_L	178_A	1.123	1.00
196_H	199_G	1.122	1.00
95_D	98_R	1.114	1.00
222_V	226_R	1.112	1.00
176_A	179_R	1.112	1.00
67_I	79_I	1.107	1.00
215_G	219_K	1.102	1.00
167_A	204_F	1.096	1.00
125_E	156_R	1.095	1.00
168_R	172_D	1.093	1.00
44_F	74_L	1.079	1.00
26_G	212_F	1.072	1.00
33_E	233_F	1.071	1.00
89_L	92_E	1.066	1.00
99_R	103_R	1.065	1.00
96_E	100_R	1.063	1.00
71_R	79_I	1.053	1.00
67_I	196_H	1.052	1.00
31_V	237_R	1.041	1.00
175_I	197_R	1.033	1.00
218_N	222_V	1.033	1.00
83_R	203_Y	1.023	1.00
151_L	186_F	1.023	1.00
157_Q	160_D	1.020	1.00
90_L	186_F	1.013	1.00
158_L	200_I	1.012	1.00
52_R	74_L	1.009	1.00
95_D	121_L	1.009	1.00
64_P	68_K	1.004	1.00
102_Q	114_K	1.004	1.00
55_I	77_A	0.994	1.00
122_K	126_N	0.989	1.00
14_Y	20_D	0.984	1.00
151_L	177_W	0.979	1.00
94_L	152_K	0.976	1.00
124_P	153_E	0.974	1.00
93_A	188_K	0.971	1.00
181_S	187_K	0.967	1.00
224_K	236_F	0.967	1.00
89_L	189_L	0.962	1.00
203_Y	209_T	0.951	1.00
191_R	195_R	0.950	1.00
7_S	12_H	0.946	1.00
166_W	169_R	0.942	1.00
6_I	15_L	0.937	1.00
101_E	145_L	0.934	1.00
32_G	42_A	0.925	1.00
32_G	39_T	0.925	1.00
17_V	20_D	0.912	1.00
1_I	18_V	0.911	1.00
78_V	206_H	0.907	1.00
7_S	10_K	0.895	1.00
93_A	189_L	0.895	1.00
38_E	42_A	0.895	1.00
83_R	160_D	0.891	1.00
153_E	156_R	0.882	1.00
168_R	198_D	0.881	1.00
225_R	228_Y	0.877	1.00
234_E	237_R	0.876	1.00
33_E	237_R	0.873	1.00
39_T	42_A	0.869	1.00
21_L	25_T	0.869	1.00
71_R	199_G	0.867	1.00
124_P	132_R	0.860	1.00
118_W	122_K	0.858	1.00
148_A	186_F	0.854	1.00
21_L	59_A	0.846	1.00
86_V	159_W	0.846	1.00
215_G	228_Y	0.840	1.00
20_D	24_D	0.838	1.00
218_N	221_K	0.837	1.00
62_M	89_L	0.836	1.00
9_R	13_R	0.831	1.00
182_R	187_K	0.830	1.00
80_V	202_N	0.828	1.00
30_W	42_A	0.827	1.00
189_L	192_T	0.825	1.00
87_V	91_N	0.823	1.00
187_K	190_A	0.822	1.00
127_L	149_Y	0.820	1.00
80_V	206_H	0.819	1.00
187_K	191_R	0.819	1.00
202_N	205_D	0.813	1.00
212_F	216_L	0.810	1.00
96_E	188_K	0.806	1.00
53_A	76_N	0.801	1.00
60_M	81_F	0.799	1.00
95_D	117_R	0.789	1.00
96_E	185_P	0.789	1.00
116_S	138_L	0.789	1.00
203_Y	207_R	0.785	1.00
64_P	196_H	0.779	1.00
116_S	134_R	0.774	1.00
106_R	114_K	0.772	1.00
134_R	137_E	0.769	1.00
132_R	136_E	0.765	1.00
65_A	68_K	0.761	1.00
30_W	43_F	0.760	1.00
38_E	41_E	0.760	1.00
194_R	197_R	0.757	1.00
189_L	193_L	0.756	1.00
139_L	146_A	0.755	1.00
119_L	134_R	0.754	1.00
8_L	13_R	0.751	1.00
62_M	86_V	0.751	1.00
6_I	220_I	0.751	1.00
127_L	131_Q	0.750	1.00
86_V	200_I	0.750	1.00
164_P	201_L	0.744	1.00
47_L	51_R	0.743	1.00
154_E	170_F	0.741	1.00
64_P	67_I	0.738	1.00
120_L	145_L	0.734	1.00
70_V	79_I	0.734	1.00
83_R	209_T	0.733	1.00
116_S	119_L	0.733	1.00
8_L	15_L	0.729	1.00
154_E	157_Q	0.729	1.00
149_Y	153_E	0.726	1.00
223_I	226_R	0.723	1.00
100_R	104_E	0.722	1.00
124_P	149_Y	0.720	1.00
171_L	175_I	0.718	1.00
80_V	203_Y	0.709	1.00
131_Q	134_R	0.708	1.00
179_R	190_A	0.704	1.00
106_R	110_R	0.704	1.00
221_K	225_R	0.704	1.00
122_K	128_T	0.700	1.00
151_L	181_S	0.697	1.00
102_Q	106_R	0.695	1.00
14_Y	18_V	0.695	1.00
172_D	176_A	0.693	1.00
30_W	237_R	0.691	1.00
1_I	58_V	0.690	1.00
20_D	27_R	0.688	1.00
147_R	150_L	0.686	1.00
91_N	152_K	0.683	1.00
15_L	233_F	0.682	1.00
184_P	188_K	0.682	1.00
94_L	120_L	0.679	1.00
18_V	30_W	0.676	1.00
44_F	73_H	0.674	1.00
235_N	238_L	0.672	1.00
112_L	141_L	0.665	1.00
37_K	69_A	0.663	1.00
178_A	190_A	0.661	1.00
3_I	60_M	0.660	1.00
91_N	121_L	0.659	1.00
177_W	180_R	0.653	1.00
162_K	166_W	0.653	1.00
137_E	140_R	0.652	1.00
7_S	14_Y	0.651	1.00
28_V	31_V	0.651	1.00
192_T	195_R	0.651	1.00
155_L	174_W	0.649	1.00
166_W	170_F	0.649	1.00
123_N	152_K	0.646	1.00
147_R	182_R	0.641	1.00
63_S	68_K	0.639	1.00
42_A	45_E	0.636	1.00
79_I	199_G	0.634	1.00
231_R	235_N	0.633	1.00
94_L	148_A	0.632	1.00
2_G	19_V	0.627	1.00
89_L	188_K	0.627	1.00
170_F	173_R	0.624	1.00
209_T	212_F	0.622	1.00
143_P	146_A	0.613	1.00
40_L	69_A	0.613	1.00
171_L	193_L	0.611	1.00
9_R	12_H	0.604	1.00
62_M	192_T	0.603	1.00
173_R	177_W	0.597	1.00
108_E	111_K	0.596	1.00
186_F	189_L	0.596	1.00
93_A	97_V	0.596	1.00
49_E	52_R	0.595	1.00
14_Y	17_V	0.592	1.00
17_V	28_V	0.590	1.00
92_E	95_D	0.587	1.00
92_E	99_R	0.587	1.00
122_K	127_L	0.587	1.00
105_L	109_K	0.587	1.00
80_V	208_I	0.580	1.00
158_L	171_L	0.580	1.00
179_R	182_R	0.579	1.00
100_R	103_R	0.578	1.00
106_R	109_K	0.574	1.00
167_A	201_L	0.570	1.00
188_K	191_R	0.570	1.00
123_N	160_D	0.570	1.00
201_L	204_F	0.570	1.00
143_P	147_R	0.566	1.00
142_N	146_A	0.566	1.00
173_R	176_A	0.565	1.00
99_R	117_R	0.563	1.00
18_V	21_L	0.560	1.00
30_W	39_T	0.558	1.00
188_K	192_T	0.557	1.00
68_K	71_R	0.557	1.00
12_H	35_R	0.556	1.00
2_G	59_A	0.555	1.00
127_L	132_R	0.554	1.00
151_L	174_W	0.552	1.00
135_L	139_L	0.551	1.00
17_V	21_L	0.549	1.00
93_A	186_F	0.549	1.00
159_W	204_F	0.547	1.00
44_F	69_A	0.547	1.00
42_A	46_R	0.546	1.00
110_R	114_K	0.545	1.00
230_F	235_N	0.544	1.00
7_S	13_R	0.542	1.00
144_K	183_L	0.541	1.00
40_L	43_F	0.541	1.00
88_K	91_N	0.538	1.00
141_L	144_K	0.537	1.00
45_E	52_R	0.537	1.00
144_K	147_R	0.535	1.00
94_L	186_F	0.535	1.00
83_R	156_R	0.534	1.00
235_N	239_R	0.533	1.00
230_F	236_F	0.533	1.00
129_E	132_R	0.532	1.00
193_L	200_I	0.531	1.00
139_L	149_Y	0.530	1.00
150_L	154_E	0.527	1.00
140_R	143_P	0.526	1.00
158_L	167_A	0.524	1.00
57_A	78_V	0.523	1.00
21_L	24_D	0.521	1.00
15_L	20_D	0.519	1.00
216_L	219_K	0.518	1.00
35_R	65_A	0.517	1.00
129_E	133_E	0.517	1.00
58_V	74_L	0.516	1.00
157_Q	170_F	0.515	1.00
158_L	161_Y	0.513	1.00
139_L	150_L	0.511	1.00
59_A	80_V	0.510	1.00
226_R	239_R	0.508	1.00
109_K	141_L	0.507	1.00
112_L	137_E	0.506	1.00
159_W	203_Y	0.506	1.00
15_L	18_V	0.505	1.00
220_I	236_F	0.505	1.00
219_K	222_V	0.502	1.00
147_R	181_S	0.502	1.00
1_I	29_L	0.501	1.00
57_A	202_N	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4cf8A	2	0.5792	76	0.921	Contact Map
1ex4A	5	0.5792	68	0.926	Contact Map
4u7bA	2	0.6417	67.5	0.926	Contact Map
1cxqA	2	0.4833	61.1	0.929	Contact Map
4fw2A	2	0.4708	60.2	0.929	Contact Map
4fw1A	2	0.6333	48.6	0.934	Contact Map
1c6vA	4	0.575	48.5	0.934	Contact Map
3oymA	3	0.4958	34.7	0.94	Contact Map
2bw3A	3	0.9417	31.8	0.941	Contact Map
3hphA	3	0.5917	31.6	0.941	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.008 seconds.