GREMLIN Database
Bac_export_3 - Bacterial export proteins, family 3
PFAM: PF01313 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 74 (72)
Sequences: 24204 (12774)
Seq/√Len: 1505.4
META: 0.91

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
23_V57_V3.3851.00
23_V53_A3.0631.00
27_V53_A2.5471.00
4_D8_Q2.5461.00
57_V61_L2.4881.00
33_L37_A2.2051.00
8_Q11_W2.1221.00
11_W15_L1.9971.00
12_T68_T1.9721.00
16_L65_M1.8281.00
24_A54_V1.8281.00
67_S71_D1.7871.00
46_S49_P1.7491.00
66_L70_V1.6631.00
18_A22_L1.6181.00
19_P23_V1.5681.00
7_R11_W1.5591.00
15_L68_T1.4681.00
21_L48_V1.4491.00
4_D7_R1.4081.00
13_A55_F1.3761.00
16_L69_L1.3261.00
12_T15_L1.2851.00
30_V34_F1.2811.00
36_A43_Q1.2431.00
25_L48_V1.2261.00
12_T16_L1.2101.00
37_A62_G1.1801.00
45_L49_P1.1801.00
22_L26_V1.1641.00
69_L73_T1.1601.00
23_V61_L1.1591.00
64_W68_T1.0621.00
56_L60_L1.0291.00
68_T71_D0.9571.00
58_L62_G0.9371.00
23_V27_V0.9031.00
8_Q12_T0.8661.00
14_L52_L0.8521.00
61_L65_M0.8501.00
25_L28_G0.8491.00
32_S40_I0.8421.00
28_G50_K0.8351.00
24_A46_S0.8341.00
14_L55_F0.8321.00
25_L42_E0.8241.00
3_L6_A0.8131.00
20_L57_V0.8121.00
8_Q72_F0.8051.00
52_L56_L0.8021.00
20_L58_L0.8001.00
47_F50_K0.7901.00
6_A10_L0.7771.00
9_A13_A0.7771.00
6_A9_A0.7721.00
29_L33_L0.7691.00
27_V49_P0.7651.00
13_A16_L0.7501.00
26_V30_V0.7411.00
12_T72_F0.7371.00
13_A17_S0.7361.00
63_P67_S0.7321.00
53_A57_V0.7321.00
34_F40_I0.7271.00
33_L40_I0.7251.00
12_T39_Q0.7201.00
9_A72_F0.7071.00
8_Q15_L0.6971.00
20_L54_V0.6901.00
5_L9_A0.6771.00
67_S70_V0.6721.00
20_L23_V0.6711.00
42_E46_S0.6631.00
36_A41_Q0.6621.00
20_L61_L0.6541.00
64_W70_V0.6511.00
9_A12_T0.6451.00
32_S45_L0.6401.00
32_S36_A0.6391.00
46_S50_K0.6381.00
3_L66_L0.6341.00
36_A39_Q0.6321.00
43_Q46_S0.6251.00
31_V44_T0.6221.00
37_A41_Q0.6151.00
70_V73_T0.6131.00
11_W14_L0.6101.00
4_D11_W0.6041.00
7_R15_L0.5851.00
3_L62_G0.5851.00
10_L14_L0.5801.00
39_Q65_M0.5761.00
25_L49_P0.5711.00
10_L59_L0.5651.00
59_L62_G0.5651.00
3_L7_R0.5571.00
58_L65_M0.5541.00
2_V6_A0.5491.00
43_Q48_V0.5471.00
41_Q45_L0.5461.00
20_L65_M0.5361.00
24_A27_V0.5361.00
30_V53_A0.5331.00
65_M68_T0.5331.00
31_V46_S0.5141.00
25_L47_F0.5081.00
46_S51_L0.5051.00
43_Q50_K0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4eneA 2 1 1.7 0.901 Contact Map
3nd0A 2 1 1.4 0.906 Contact Map
4pd6A 3 0.4189 1.3 0.907 Contact Map
4u9nA 2 0.9324 1 0.915 Contact Map
4kppA 1 0.3919 0.8 0.918 Contact Map
4wqkA 1 0.4459 0.8 0.919 Contact Map
4pj0R 1 0.3649 0.7 0.923 Contact Map
1xl3C 1 0.3378 0.7 0.923 Contact Map
1oedA 1 0.4595 0.7 0.923 Contact Map
3mktA 1 0.8919 0.6 0.925 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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