GREMLIN Database
Q9HSZ5 - Uncharacterized protein
UniProt: Q9HSZ5 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 69 (64)
Sequences: 844 (364)
Seq/√Len: 45.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
21_V26_L4.4871.00
2_V29_A3.0161.00
2_V37_A2.8521.00
47_Y60_L2.4811.00
45_I64_R2.4691.00
21_V35_V2.4171.00
51_P60_L2.3681.00
11_E18_S2.1241.00
21_V25_D2.0160.99
54_W57_G1.9910.99
21_V29_A1.8220.99
51_P55_V1.8210.99
14_I23_S1.7210.98
47_Y64_R1.5560.96
2_V21_V1.4480.94
58_K62_R1.2660.89
4_A10_T1.2590.89
9_C17_Y1.2500.89
8_S18_S1.2440.89
51_P57_G1.2360.88
45_I63_Y1.2350.88
4_A26_L1.1390.84
9_C19_I1.0950.81
8_S61_E1.0370.77
10_T24_T1.0230.76
1_M16_A1.0210.76
3_G33_G0.9840.74
61_E64_R0.9840.74
45_I54_W0.9780.73
3_G42_T0.9610.72
27_A31_A0.9500.71
8_S28_F0.9490.71
11_E19_I0.9480.71
28_F34_W0.9460.71
46_N53_G0.9340.70
37_A41_E0.8880.66
50_E53_G0.8810.65
10_T27_A0.8560.63
46_N50_E0.8430.62
3_G39_V0.8430.62
26_L29_A0.7820.56
24_T42_T0.7730.55
33_G37_A0.7700.55
9_C24_T0.7680.54
25_D33_G0.7560.53
25_D35_V0.7510.53
3_G18_S0.7500.53
21_V32_F0.7320.51
29_A35_V0.7320.51
48_V52_T0.7320.51
30_M53_G0.7220.50
22_G25_D0.7200.50
4_A23_S0.7190.50
38_R41_E0.7170.50
45_I48_V0.7160.49
20_G36_W0.7150.49
32_F44_R0.7110.49
2_V35_V0.6950.47
34_W39_V0.6900.47
14_I18_S0.6790.46
19_I38_R0.6670.45
50_E55_V0.6650.44
13_A63_Y0.6570.44
33_G39_V0.6570.44
13_A45_I0.6430.42
4_A30_M0.6420.42
3_G41_E0.6420.42
29_A48_V0.6380.42
8_S24_T0.6310.41
15_G53_G0.6100.39
13_A34_W0.6010.38
36_W39_V0.6000.38
11_E37_A0.5970.38
1_M26_L0.5940.38
10_T58_K0.5930.38
50_E63_Y0.5910.37
18_S25_D0.5900.37
3_G11_E0.5890.37
47_Y63_Y0.5860.37
51_P54_W0.5800.36
3_G60_L0.5790.36
23_S42_T0.5790.36
42_T57_G0.5710.36
15_G47_Y0.5630.35
31_A37_A0.5620.35
24_T33_G0.5600.35
27_A58_K0.5600.35
2_V14_I0.5430.33
16_A56_S0.5400.33
1_M43_T0.5290.32
15_G26_L0.5270.32
51_P63_Y0.5250.32
35_V39_V0.5120.31
31_A54_W0.5030.30
19_I37_A0.5020.30
20_G25_D0.5000.30
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4kp1A 1 1 100 0.173 Contact Map
4kp2A 2 0.9855 100 0.192 Contact Map
1c96A 1 1 99.9 0.202 Contact Map
2b3yA 1 1 99.9 0.217 Contact Map
1l5jA 1 0.9565 99.9 0.319 Contact Map
3nioA 5 0.8986 9.7 0.921 Contact Map
1wohA 5 0.942 8.5 0.923 Contact Map
3g5sA 1 0.8696 8.3 0.924 Contact Map
4mykA 3 0.8261 7 0.926 Contact Map
2cevA 5 0.9565 6.5 0.927 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0047 seconds.