Q9HSV4 - HALSA - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

Q9HSV4 - LPS glycosyltransferase

UniProt:	Q9HSV4	Sequences: MARLLSELQPSEFDITVVAIADTPPDVVSMLPDHVEVKHLKMTRRTALLQLGEISKIVKSTDILVCSLFHATAIGVPLGLLLQVPKLLVWQHSTSYSNQIRSAYYRLAYRAADRVLADSDAVMEMLVDSVGVPDQKISTLPIAGIDVKEYQPSKTHPSHENITVSTVGRLANVKGYDDLIRCARDIGDDLQFQIAGEGEERERLESKTPDNVNFQGMVPNEQIPQFLNNSDIYFQPSKYEGLCMAVIEAMACGLPVVASDVGGITESVVPGETGFLCRPRDIDCFSERLQQLSENPALRKQMGTAGRKRVISEYSQKALARQFRKAIDQTETV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	333 (307)
Sequences:	56669 (48454)
Seq/√Len:	2765.4

ECOLI - WCAL RFAG GLGA RFAB WBBK WCAI WCAC
BACSU - YPJH COTSA TUAC GLGA EPSF YTCC EPSD YQGM TUAH YKVP CGEB TAGE
HALSA - Q9HSV4 Q9HQQ0 Q9HSV2 Q9HSW1 Q9HS45 Q9HRP8 Q9HRP9 Q9HQT2
SULSO - Q97UM0 Q97V61 Q97V80 Q97VL4 Q980C8 Q97XT7 Q97XT1 Q97ZD3 Q97XU2 Q7LXI2 Q97XT8 Q97XT9 Q97UU3 Q97XF6 Q97XT5 Q7LXM9 Q7LXF8 Q97XT6 Q7LXF5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
165_S	230_S	4.747	1.00
191_Q	213_N	3.561	1.00
233_Y	249_A	3.101	1.00
114_R	138_S	3.088	1.00
163_T	193_Q	2.952	1.00
65_V	327_I	2.906	1.00
185_D	286_S	2.726	1.00
193_Q	215_Q	2.718	1.00
309_R	313_E	2.696	1.00
161_N	191_Q	2.635	1.00
166_T	176_Y	2.627	1.00
201_R	205_E	2.579	1.00
181_R	207_K	2.220	1.00
123_M	127_V	2.207	1.00
16_T	61_T	2.166	1.00
175_G	178_D	2.163	1.00
181_R	282_I	2.136	1.00
162_I	293_S	2.106	1.00
163_T	191_Q	2.023	1.00
195_A	226_F	2.002	1.00
260_D	265_T	1.993	1.00
288_R	291_Q	1.966	1.00
193_Q	213_N	1.959	1.00
295_N	298_L	1.930	1.00
16_T	38_K	1.918	1.00
183_A	192_F	1.908	1.00
164_V	232_I	1.895	1.00
273_T	309_R	1.879	1.00
163_T	229_N	1.878	1.00
200_E	203_R	1.868	1.00
162_I	231_D	1.862	1.00
269_V	272_E	1.859	1.00
299_R	303_G	1.850	1.00
185_D	283_D	1.849	1.00
291_Q	298_L	1.841	1.00
268_V	274_G	1.828	1.00
144_G	316_Q	1.823	1.00
253_G	307_R	1.815	1.00
65_V	89_V	1.810	1.00
179_L	192_F	1.767	1.00
275_F	288_R	1.764	1.00
175_G	238_K	1.747	1.00
318_A	322_Q	1.718	1.00
120_D	123_M	1.708	1.00
233_Y	254_L	1.706	1.00
114_R	326_A	1.671	1.00
123_M	139_T	1.665	1.00
291_Q	295_N	1.663	1.00
120_D	266_E	1.660	1.00
117_A	137_I	1.641	1.00
260_D	278_R	1.635	1.00
278_R	284_C	1.627	1.00
167_V	223_I	1.621	1.00
290_Q	294_E	1.621	1.00
269_V	309_R	1.595	1.00
88_L	112_A	1.589	1.00
187_G	290_Q	1.572	1.00
272_E	305_A	1.572	1.00
173_V	239_Y	1.566	1.00
179_L	234_F	1.551	1.00
183_A	190_L	1.550	1.00
219_P	222_Q	1.530	1.00
284_C	288_R	1.510	1.00
281_D	284_C	1.508	1.00
269_V	273_T	1.499	1.00
298_L	301_Q	1.482	1.00
123_M	137_I	1.463	1.00
275_F	291_Q	1.456	1.00
120_D	139_T	1.452	1.00
324_R	328_D	1.437	1.00
195_A	215_Q	1.434	1.00
186_I	290_Q	1.429	1.00
163_T	231_D	1.427	1.00
16_T	36_E	1.412	1.00
301_Q	305_A	1.409	1.00
193_Q	226_F	1.389	1.00
230_S	254_L	1.386	1.00
178_D	282_I	1.383	1.00
258_A	264_I	1.381	1.00
178_D	238_K	1.362	1.00
193_Q	230_S	1.362	1.00
308_K	312_S	1.361	1.00
222_Q	225_Q	1.360	1.00
218_V	222_Q	1.350	1.00
116_L	323_F	1.345	1.00
282_I	286_S	1.341	1.00
176_Y	194_I	1.323	1.00
177_D	207_K	1.318	1.00
185_D	282_I	1.315	1.00
166_T	179_L	1.301	1.00
158_S	161_N	1.298	1.00
277_C	288_R	1.292	1.00
116_L	326_A	1.292	1.00
170_L	194_I	1.284	1.00
224_P	252_C	1.281	1.00
117_A	123_M	1.275	1.00
242_L	247_I	1.274	1.00
182_C	285_F	1.272	1.00
164_V	234_F	1.264	1.00
220_N	223_I	1.260	1.00
305_A	308_K	1.246	1.00
164_V	289_L	1.232	1.00
197_E	201_R	1.229	1.00
165_S	195_A	1.212	1.00
318_A	321_R	1.209	1.00
284_C	287_E	1.201	1.00
322_Q	325_K	1.200	1.00
127_V	134_D	1.199	1.00
228_N	252_C	1.198	1.00
150_Y	252_C	1.187	1.00
162_I	232_I	1.180	1.00
66_C	86_K	1.179	1.00
120_D	124_E	1.178	1.00
223_I	227_L	1.177	1.00
133_P	136_K	1.172	1.00
91_Q	244_M	1.144	1.00
303_G	306_G	1.137	1.00
178_D	259_S	1.135	1.00
246_V	264_I	1.135	1.00
124_E	127_V	1.134	1.00
316_Q	319_L	1.134	1.00
235_Q	246_V	1.132	1.00
149_E	224_P	1.128	1.00
169_R	173_V	1.118	1.00
118_D	122_V	1.114	1.00
237_S	240_E	1.112	1.00
270_P	288_R	1.112	1.00
78_L	82_L	1.111	1.00
177_D	181_R	1.107	1.00
259_S	277_C	1.105	1.00
286_S	290_Q	1.104	1.00
319_L	322_Q	1.096	1.00
300_K	304_T	1.096	1.00
162_I	190_L	1.094	1.00
178_D	181_R	1.094	1.00
235_Q	245_A	1.084	1.00
253_G	304_T	1.084	1.00
296_P	299_R	1.084	1.00
117_A	126_L	1.084	1.00
238_K	280_R	1.083	1.00
315_S	318_A	1.080	1.00
236_P	285_F	1.077	1.00
243_C	264_I	1.074	1.00
163_T	230_S	1.074	1.00
178_D	280_R	1.069	1.00
298_L	302_M	1.068	1.00
227_L	252_C	1.068	1.00
118_D	143_A	1.064	1.00
67_S	91_Q	1.054	1.00
319_L	323_F	1.051	1.00
277_C	285_F	1.049	1.00
258_A	276_L	1.046	1.00
275_F	302_M	1.039	1.00
292_L	302_M	1.037	1.00
164_V	183_A	1.035	1.00
202_E	205_E	1.034	1.00
117_A	122_V	1.031	1.00
215_Q	226_F	1.028	1.00
254_L	303_G	1.025	1.00
143_A	244_M	1.023	1.00
202_E	206_S	1.019	1.00
233_Y	245_A	1.015	1.00
150_Y	224_P	1.013	1.00
118_D	241_G	1.011	1.00
162_I	189_D	1.005	1.00
55_S	59_K	1.002	1.00
193_Q	229_N	0.998	1.00
263_G	266_E	0.997	1.00
250_M	256_V	0.996	1.00
167_V	227_L	0.981	1.00
161_N	189_D	0.979	1.00
165_S	226_F	0.977	1.00
195_A	218_V	0.975	1.00
177_D	238_K	0.973	1.00
224_P	228_N	0.964	1.00
208_T	214_F	0.963	1.00
112_A	115_V	0.962	1.00
186_I	190_L	0.960	1.00
275_F	292_L	0.959	1.00
125_M	128_D	0.957	1.00
287_E	291_Q	0.956	1.00
246_V	258_A	0.956	1.00
147_V	315_S	0.952	1.00
187_G	294_E	0.949	1.00
144_G	319_L	0.947	1.00
167_V	195_A	0.931	1.00
250_M	306_G	0.931	1.00
179_L	236_P	0.925	1.00
296_P	300_K	0.923	1.00
124_E	128_D	0.921	1.00
174_K	240_E	0.919	1.00
166_T	194_I	0.916	1.00
86_K	112_A	0.915	1.00
249_A	254_L	0.914	1.00
302_M	305_A	0.908	1.00
257_V	277_C	0.907	1.00
183_A	211_N	0.905	1.00
321_R	325_K	0.903	1.00
273_T	306_G	0.902	1.00
190_L	293_S	0.901	1.00
262_G	265_T	0.893	1.00
138_S	326_A	0.892	1.00
174_K	245_A	0.891	1.00
303_G	307_R	0.891	1.00
218_V	226_F	0.890	1.00
304_T	308_K	0.890	1.00
177_D	203_R	0.886	1.00
235_Q	264_I	0.883	1.00
240_E	243_C	0.883	1.00
191_Q	211_N	0.879	1.00
186_I	289_L	0.878	1.00
258_A	268_V	0.877	1.00
178_D	285_F	0.874	1.00
246_V	256_V	0.873	1.00
300_K	303_G	0.872	1.00
203_R	207_K	0.871	1.00
275_F	298_L	0.869	1.00
66_C	88_L	0.867	1.00
215_Q	218_V	0.862	1.00
182_C	286_S	0.859	1.00
186_I	293_S	0.858	1.00
255_P	303_G	0.858	1.00
227_L	254_L	0.855	1.00
146_D	149_E	0.850	1.00
77_P	81_L	0.844	1.00
55_S	81_L	0.842	1.00
250_M	309_R	0.841	1.00
315_S	319_L	0.841	1.00
232_I	292_L	0.838	1.00
246_V	267_S	0.835	1.00
159_H	162_I	0.833	1.00
174_K	237_S	0.833	1.00
180_I	208_T	0.832	1.00
261_V	264_I	0.830	1.00
226_F	229_N	0.827	1.00
127_V	137_I	0.826	1.00
87_L	116_L	0.824	1.00
171_A	199_E	0.822	1.00
270_P	273_T	0.821	1.00
166_T	236_P	0.820	1.00
14_D	36_E	0.820	1.00
203_R	206_S	0.820	1.00
268_V	276_L	0.819	1.00
181_R	185_D	0.819	1.00
220_N	224_P	0.816	1.00
250_M	273_T	0.814	1.00
116_L	140_L	0.813	1.00
121_A	124_E	0.808	1.00
257_V	288_R	0.807	1.00
234_F	289_L	0.806	1.00
79_G	86_K	0.803	1.00
278_R	281_D	0.800	1.00
186_I	286_S	0.795	1.00
138_S	322_Q	0.794	1.00
168_G	174_K	0.793	1.00
52_G	56_K	0.792	1.00
316_Q	320_A	0.782	1.00
260_D	276_L	0.775	1.00
158_S	191_Q	0.775	1.00
61_T	84_V	0.774	1.00
140_L	326_A	0.772	1.00
166_T	192_F	0.771	1.00
181_R	184_R	0.771	1.00
165_S	227_L	0.771	1.00
225_Q	229_N	0.770	1.00
182_C	282_I	0.770	1.00
309_R	314_Y	0.765	1.00
52_G	55_S	0.763	1.00
153_S	228_N	0.762	1.00
255_P	292_L	0.761	1.00
225_Q	228_N	0.759	1.00
118_D	244_M	0.757	1.00
65_V	323_F	0.754	1.00
166_T	233_Y	0.754	1.00
232_I	289_L	0.751	1.00
302_M	306_G	0.751	1.00
172_N	238_K	0.749	1.00
87_L	114_R	0.749	1.00
48_L	52_G	0.747	1.00
103_A	106_R	0.744	1.00
103_A	107_L	0.743	1.00
231_D	299_R	0.742	1.00
167_V	233_Y	0.742	1.00
172_N	177_D	0.741	1.00
121_A	125_M	0.738	1.00
287_E	290_Q	0.738	1.00
323_F	327_I	0.733	1.00
283_D	287_E	0.732	1.00
259_S	279_P	0.730	1.00
307_R	310_V	0.727	1.00
141_P	322_Q	0.726	1.00
242_L	314_Y	0.726	1.00
85_P	113_D	0.725	1.00
271_G	291_Q	0.725	1.00
63_I	327_I	0.724	1.00
270_P	275_F	0.721	1.00
301_Q	304_T	0.720	1.00
107_L	111_A	0.719	1.00
259_S	285_F	0.718	1.00
68_L	71_A	0.717	1.00
146_D	150_Y	0.717	1.00
265_T	276_L	0.716	1.00
67_S	89_V	0.712	1.00
247_I	314_Y	0.708	1.00
164_V	190_L	0.706	1.00
257_V	292_L	0.705	1.00
79_G	82_L	0.705	1.00
168_G	176_Y	0.705	1.00
91_Q	118_D	0.703	1.00
51_L	55_S	0.698	1.00
140_L	143_A	0.690	1.00
140_L	323_F	0.690	1.00
320_A	324_R	0.689	1.00
184_R	209_P	0.688	1.00
291_Q	294_E	0.687	1.00
177_D	200_E	0.686	1.00
243_C	246_V	0.685	1.00
63_I	87_L	0.672	1.00
87_L	327_I	0.670	1.00
66_C	72_T	0.669	1.00
273_T	305_A	0.667	1.00
283_D	286_S	0.666	1.00
89_V	323_F	0.666	1.00
99_Q	103_A	0.666	1.00
325_K	328_D	0.665	1.00
297_A	301_Q	0.664	1.00
169_R	174_K	0.664	1.00
295_N	299_R	0.662	1.00
198_G	201_R	0.656	1.00
235_Q	243_C	0.655	1.00
204_L	208_T	0.655	1.00
147_V	251_A	0.654	1.00
250_M	303_G	0.653	1.00
121_A	265_T	0.652	1.00
164_V	293_S	0.652	1.00
49_L	53_E	0.650	1.00
123_M	134_D	0.648	1.00
292_L	299_R	0.648	1.00
162_I	296_P	0.648	1.00
183_A	186_I	0.647	1.00
234_F	285_F	0.646	1.00
187_G	190_L	0.646	1.00
127_V	131_G	0.644	1.00
321_R	324_R	0.643	1.00
61_T	64_L	0.640	1.00
106_R	110_R	0.640	1.00
165_S	233_Y	0.640	1.00
205_E	208_T	0.638	1.00
90_W	122_V	0.637	1.00
196_G	216_G	0.635	1.00
188_D	290_Q	0.633	1.00
237_S	245_A	0.633	1.00
180_I	212_V	0.631	1.00
64_L	84_V	0.629	1.00
162_I	165_S	0.629	1.00
306_G	309_R	0.628	1.00
140_L	322_Q	0.628	1.00
122_V	125_M	0.627	1.00
268_V	273_T	0.626	1.00
99_Q	102_S	0.624	1.00
189_D	211_N	0.624	1.00
170_L	201_R	0.623	1.00
204_L	207_K	0.622	1.00
182_C	289_L	0.621	1.00
245_A	249_A	0.621	1.00
170_L	176_Y	0.620	1.00
226_F	230_S	0.620	1.00
237_S	241_G	0.619	1.00
208_T	212_V	0.618	1.00
86_K	113_D	0.617	1.00
178_D	182_C	0.617	1.00
151_Q	228_N	0.614	1.00
80_L	111_A	0.612	1.00
66_C	75_G	0.610	1.00
175_G	280_R	0.610	1.00
227_L	245_A	0.604	1.00
119_S	122_V	0.602	1.00
165_S	254_L	0.600	1.00
47_A	50_Q	0.598	1.00
200_E	204_L	0.598	1.00
54_I	57_I	0.598	1.00
233_Y	256_V	0.595	1.00
188_D	294_E	0.594	1.00
182_C	234_F	0.592	1.00
197_E	217_M	0.591	1.00
297_A	300_K	0.589	1.00
313_E	318_A	0.589	1.00
277_C	284_C	0.588	1.00
151_Q	154_K	0.587	1.00
232_I	257_V	0.585	1.00
304_T	307_R	0.584	1.00
95_S	98_N	0.583	1.00
165_S	193_Q	0.583	1.00
169_R	245_A	0.580	1.00
243_C	247_I	0.580	1.00
100_I	103_A	0.579	1.00
172_N	200_E	0.577	1.00
53_E	56_K	0.577	1.00
236_P	259_S	0.576	1.00
127_V	130_V	0.576	1.00
117_A	139_T	0.575	1.00
162_I	299_R	0.575	1.00
179_L	183_A	0.575	1.00
19_A	37_V	0.573	1.00
317_K	321_R	0.573	1.00
175_G	259_S	0.573	1.00
305_A	309_R	0.572	1.00
205_E	214_F	0.571	1.00
182_C	186_I	0.569	1.00
187_G	211_N	0.567	1.00
195_A	223_I	0.567	1.00
175_G	236_P	0.566	1.00
163_T	226_F	0.565	1.00
64_L	79_G	0.562	1.00
247_I	310_V	0.562	1.00
232_I	299_R	0.559	1.00
121_A	266_E	0.559	1.00
299_R	302_M	0.557	1.00
261_V	265_T	0.556	1.00
249_A	256_V	0.555	1.00
257_V	289_L	0.554	1.00
91_Q	143_A	0.554	1.00
176_Y	200_E	0.553	1.00
250_M	310_V	0.553	1.00
122_V	241_G	0.550	1.00
107_L	110_R	0.549	1.00
53_E	58_V	0.547	1.00
148_K	151_Q	0.546	1.00
255_P	299_R	0.539	1.00
231_D	296_P	0.538	1.00
160_E	189_D	0.537	1.00
31_L	34_H	0.536	1.00
237_S	243_C	0.535	1.00
192_F	212_V	0.532	1.00
89_V	327_I	0.531	1.00
89_V	116_L	0.530	1.00
118_D	243_C	0.529	1.00
75_G	79_G	0.527	1.00
30_M	39_H	0.527	1.00
53_E	57_I	0.526	1.00
161_N	229_N	0.526	1.00
177_D	204_L	0.525	1.00
227_L	233_Y	0.525	1.00
220_N	226_F	0.522	1.00
218_V	223_I	0.522	1.00
94_T	97_S	0.521	1.00
247_I	267_S	0.515	1.00
261_V	279_P	0.515	1.00
50_Q	53_E	0.514	1.00
244_M	248_E	0.513	1.00
160_E	163_T	0.513	1.00
188_D	211_N	0.509	1.00
104_Y	107_L	0.508	1.00
147_V	310_V	0.507	1.00
39_H	42_M	0.507	1.00
219_P	223_I	0.506	1.00
149_E	220_N	0.505	1.00
184_R	207_K	0.504	1.00
260_D	279_P	0.503	1.00
227_L	249_A	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2r60A	1	0.994	100	0.171	Contact Map
4n9wA	1	0.9399	100	0.181	Contact Map
3c48A	2	0.982	100	0.195	Contact Map
1rzuA	1	0.985	100	0.2	Contact Map
3froA	3	0.988	100	0.203	Contact Map
2qzsA	1	0.976	100	0.205	Contact Map
2x0dA	2	0.9279	100	0.22	Contact Map
3okpA	1	0.979	100	0.226	Contact Map
2x6qA	1	0.961	100	0.226	Contact Map
2jjmA	4	0.9489	100	0.226	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0099 seconds.