Q9HSR9 - HALSA - GREMLIN Contacts

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Q9HSR9 - Type I restriction modification enzyme, M subunit

UniProt:	Q9HSR9	Sequences: MSLTLDELDSHLFKCADIIRDAVDPTDYKEYILPLVFYKAISDEYEQEREEIVEEYGEDFADNANLYDVPIVPEGHRWNDLRQESENVDEAINNAFTEFTQANPDLSGIFNANFMEAGGLTDDRLIKLVEHLSTYDLDRDSVPPDMLGEAYMDLVRHFAEEEGKSGGQFFTPPHIVQLCVRLVDDFADGMTFHDPTVGSGGMLTEAAKYYREAQGGDPSKLTFTGQEINPDIAAIARMNLSLHTLNGEIERGDSLASPGFTDGDDLERFDRVLANFPFSADWAKDDLQDDQYGRFDWHTKLPRADRGDYAFIMHIAEQLKEPDCGDESGGKAAIVIPHGVLFRKHEQRYRQPMLENDLVEAIVGLPENLFQNNSIPSAILVLNTDKPADREGEVQFIHAADEAFYEELSNQNELTDDGLDHIVENFDDWTTEERVSRTVGIEEIEENDFNLNIALYVDTTEPEEDIDVNEELAELRELQAEREEIESRMTEHMEALQYE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	499 (453)
Sequences:	6850 (4439)
Seq/√Len:	208.6

ECOLI - T1MK
BACSU - YEEA YTXK
HALSA - Q9HSR9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
351_Q	355_E	5.697	1.00
319_L	332_A	4.333	1.00
179_C	333_A	3.862	1.00
270_D	320_K	3.669	1.00
348_R	351_Q	3.525	1.00
315_I	332_A	3.406	1.00
420_D	424_E	3.256	1.00
75_G	80_D	3.243	1.00
415_T	418_G	3.184	1.00
181_R	209_Y	3.072	1.00
442_E	445_E	3.021	1.00
437_R	443_E	3.019	1.00
312_I	336_I	2.929	1.00
352_P	356_N	2.812	1.00
179_C	273_L	2.782	1.00
442_E	446_E	2.659	1.00
477_E	481_E	2.633	1.00
333_A	381_V	2.624	1.00
192_F	206_A	2.570	1.00
440_G	443_E	2.549	1.00
445_E	449_F	2.534	1.00
315_I	334_I	2.448	1.00
197_V	236_A	2.425	1.00
480_A	484_E	2.393	1.00
441_I	445_E	2.336	1.00
394_V	444_I	2.304	1.00
360_E	383_N	2.239	1.00
177_Q	205_E	2.168	1.00
14_K	17_D	2.112	1.00
347_Q	351_Q	2.104	1.00
197_V	225_G	2.082	1.00
474_E	478_L	1.984	1.00
481_E	484_E	1.945	1.00
190_M	271_R	1.930	1.00
193_H	318_Q	1.923	1.00
474_E	477_E	1.919	1.00
417_D	420_D	1.916	1.00
196_T	311_F	1.893	1.00
482_R	485_I	1.888	1.00
90_E	94_N	1.886	1.00
320_K	329_G	1.870	1.00
216_G	220_K	1.863	1.00
196_T	274_A	1.859	1.00
467_D	470_E	1.855	1.00
478_L	481_E	1.851	1.00
393_E	440_G	1.849	1.00
479_Q	482_R	1.832	1.00
476_R	480_A	1.831	1.00
200_G	236_A	1.824	1.00
190_M	331_K	1.804	1.00
468_V	472_L	1.804	1.00
316_A	357_D	1.801	1.00
423_V	426_F	1.789	1.00
131_H	134_T	1.770	1.00
333_A	379_I	1.769	1.00
425_N	435_V	1.749	1.00
478_L	482_R	1.746	1.00
441_I	449_F	1.743	1.00
368_N	374_S	1.741	1.00
341_L	362_I	1.740	1.00
89_D	93_N	1.721	1.00
197_V	249_I	1.718	1.00
39_K	43_D	1.718	1.00
453_I	457_V	1.691	1.00
338_H	364_G	1.663	1.00
354_L	394_V	1.661	1.00
418_G	421_H	1.658	1.00
168_Q	229_N	1.655	1.00
473_A	477_E	1.646	1.00
181_R	423_V	1.642	1.00
319_L	330_G	1.639	1.00
367_E	374_S	1.625	1.00
177_Q	416_D	1.614	1.00
471_E	475_L	1.613	1.00
419_L	423_V	1.611	1.00
429_W	432_E	1.610	1.00
355_E	445_E	1.604	1.00
373_N	376_P	1.596	1.00
183_V	271_R	1.583	1.00
331_K	383_N	1.578	1.00
48_E	51_E	1.574	1.00
404_F	407_E	1.561	1.00
279_S	307_G	1.558	1.00
103_N	106_L	1.551	1.00
274_A	315_I	1.544	1.00
316_A	353_M	1.541	1.00
367_E	376_P	1.533	1.00
454_A	458_D	1.527	1.00
443_E	446_E	1.526	1.00
335_V	379_I	1.520	1.00
421_H	424_E	1.513	1.00
10_S	14_K	1.509	1.00
479_Q	483_E	1.508	1.00
227_E	233_A	1.505	1.00
193_H	272_V	1.501	1.00
368_N	373_N	1.496	1.00
466_I	470_E	1.491	1.00
405_Y	408_L	1.482	1.00
472_L	476_R	1.474	1.00
183_V	333_A	1.465	1.00
453_I	456_Y	1.463	1.00
355_E	449_F	1.461	1.00
399_A	422_I	1.458	1.00
177_Q	181_R	1.455	1.00
421_H	425_N	1.450	1.00
78_W	82_R	1.449	1.00
316_A	358_L	1.441	1.00
450_N	453_I	1.436	1.00
184_D	209_Y	1.436	1.00
74_E	77_R	1.428	1.00
453_I	458_D	1.423	1.00
236_A	249_I	1.415	1.00
233_A	249_I	1.405	1.00
468_V	471_E	1.397	1.00
27_D	30_E	1.397	1.00
309_Y	346_E	1.382	1.00
361_A	381_V	1.380	1.00
87_N	92_I	1.375	1.00
321_E	384_T	1.375	1.00
205_E	208_K	1.369	1.00
471_E	474_E	1.362	1.00
126_I	130_E	1.357	1.00
347_Q	448_D	1.356	1.00
338_H	376_P	1.350	1.00
178_L	182_L	1.350	1.00
451_L	457_V	1.343	1.00
423_V	427_D	1.340	1.00
227_E	232_I	1.338	1.00
180_V	209_Y	1.332	1.00
449_F	453_I	1.327	1.00
180_V	273_L	1.325	1.00
184_D	427_D	1.322	1.00
284_K	288_Q	1.315	1.00
363_V	379_I	1.311	1.00
457_V	460_T	1.308	1.00
444_I	448_D	1.291	1.00
452_N	456_Y	1.282	1.00
362_I	380_L	1.282	1.00
452_N	455_L	1.273	1.00
343_R	346_E	1.272	1.00
468_V	479_Q	1.271	1.00
451_L	456_Y	1.261	1.00
291_Q	310_A	1.260	1.00
73_P	78_W	1.247	1.00
179_C	379_I	1.240	1.00
477_E	480_A	1.230	1.00
451_L	454_A	1.227	1.00
424_E	427_D	1.227	1.00
87_N	91_A	1.225	1.00
79_N	83_Q	1.217	1.00
339_G	343_R	1.213	1.00
353_M	358_L	1.210	1.00
271_R	331_K	1.210	1.00
98_E	101_Q	1.207	1.00
46_E	79_N	1.205	1.00
458_D	461_E	1.194	1.00
62_D	65_N	1.193	1.00
332_A	382_L	1.190	1.00
331_K	360_E	1.188	1.00
480_A	483_E	1.182	1.00
253_D	256_A	1.180	1.00
475_L	479_Q	1.178	1.00
193_H	269_F	1.170	1.00
193_H	254_S	1.169	1.00
123_D	127_K	1.168	1.00
186_F	190_M	1.166	1.00
176_V	202_M	1.164	1.00
11_H	134_T	1.164	1.00
78_W	81_L	1.163	1.00
455_L	458_D	1.161	1.00
441_I	444_I	1.160	1.00
89_D	96_F	1.159	1.00
444_I	456_Y	1.159	1.00
454_A	457_V	1.156	1.00
190_M	270_D	1.140	1.00
329_G	385_D	1.137	1.00
94_N	97_T	1.137	1.00
466_I	474_E	1.130	1.00
336_I	380_L	1.129	1.00
338_H	342_F	1.128	1.00
285_D	289_D	1.128	1.00
92_I	95_A	1.124	1.00
437_R	440_G	1.120	1.00
62_D	66_L	1.112	1.00
462_P	465_D	1.110	1.00
439_V	443_E	1.107	1.00
312_I	334_I	1.105	1.00
195_P	274_A	1.100	1.00
87_N	95_A	1.098	1.00
466_I	471_E	1.090	1.00
24_D	29_K	1.089	1.00
91_A	94_N	1.087	1.00
431_T	437_R	1.085	1.00
451_L	458_D	1.078	1.00
452_N	457_V	1.076	1.00
250_E	259_G	1.075	1.00
73_P	76_H	1.074	1.00
448_D	452_N	1.071	1.00
449_F	456_Y	1.062	1.00
339_G	346_E	1.062	1.00
456_Y	461_E	1.060	1.00
93_N	96_F	1.059	1.00
195_P	315_I	1.058	1.00
366_P	377_S	1.057	1.00
450_N	454_A	1.055	1.00
96_F	100_T	1.054	1.00
55_E	58_E	1.053	1.00
368_N	376_P	1.049	1.00
393_E	438_T	1.049	1.00
95_A	99_F	1.044	1.00
447_N	450_N	1.040	1.00
449_F	455_L	1.036	1.00
118_G	121_T	1.036	1.00
444_I	449_F	1.030	1.00
471_E	478_L	1.029	1.00
339_G	376_P	1.027	1.00
467_D	471_E	1.023	1.00
475_L	482_R	1.022	1.00
431_T	436_S	1.021	1.00
308_D	337_P	1.018	1.00
357_D	386_K	1.018	1.00
359_V	382_L	1.015	1.00
336_I	378_A	1.015	1.00
447_N	455_L	1.014	1.00
91_A	95_A	1.014	1.00
226_Q	252_G	1.009	1.00
127_K	131_H	1.007	1.00
473_A	480_A	1.007	1.00
439_V	444_I	1.006	1.00
73_P	77_R	1.006	1.00
180_V	206_A	1.002	1.00
255_L	311_F	0.999	1.00
203_L	225_G	0.999	1.00
275_N	370_F	0.998	1.00
312_I	380_L	0.998	1.00
476_R	479_Q	0.994	1.00
470_E	474_E	0.991	1.00
414_L	418_G	0.990	1.00
424_E	428_D	0.985	1.00
74_E	80_D	0.985	1.00
77_R	82_R	0.982	1.00
339_G	345_H	0.979	1.00
209_Y	212_E	0.978	1.00
359_V	362_I	0.975	1.00
87_N	90_E	0.973	1.00
89_D	95_A	0.972	1.00
353_M	359_V	0.968	1.00
272_V	319_L	0.968	1.00
428_D	432_E	0.967	1.00
478_L	485_I	0.967	1.00
404_F	408_L	0.959	1.00
395_Q	399_A	0.957	1.00
446_E	452_N	0.953	0.99
152_M	170_F	0.953	0.99
338_H	373_N	0.948	0.99
88_V	91_A	0.947	0.99
444_I	453_I	0.945	0.99
369_L	373_N	0.943	0.99
461_E	465_D	0.943	0.99
82_R	133_S	0.940	0.99
438_T	441_I	0.939	0.99
469_N	473_A	0.938	0.99
357_D	384_T	0.934	0.99
357_D	392_G	0.934	0.99
18_I	127_K	0.933	0.99
466_I	472_L	0.929	0.99
468_V	475_L	0.928	0.99
440_G	445_E	0.924	0.99
314_H	317_E	0.924	0.99
450_N	457_V	0.924	0.99
431_T	438_T	0.919	0.99
207_A	223_F	0.918	0.99
447_N	453_I	0.917	0.99
473_A	483_E	0.917	0.99
475_L	478_L	0.916	0.99
50_E	54_E	0.914	0.99
96_F	99_F	0.912	0.99
368_N	375_I	0.911	0.99
338_H	375_I	0.910	0.99
88_V	93_N	0.908	0.99
65_N	68_D	0.905	0.99
30_E	231_D	0.904	0.99
85_S	91_A	0.903	0.99
53_V	56_Y	0.902	0.99
191_T	224_T	0.900	0.99
106_L	110_F	0.900	0.99
472_L	479_Q	0.899	0.99
365_L	369_L	0.898	0.99
278_F	375_I	0.897	0.99
416_D	420_D	0.895	0.99
93_N	97_T	0.893	0.99
159_A	162_E	0.892	0.99
477_E	483_E	0.891	0.99
109_I	112_A	0.890	0.99
252_G	257_S	0.888	0.99
473_A	476_R	0.887	0.99
77_R	81_L	0.887	0.99
373_N	377_S	0.887	0.99
200_G	203_L	0.887	0.99
303_R	310_A	0.886	0.99
472_L	482_R	0.886	0.99
280_A	283_A	0.885	0.99
449_F	457_V	0.884	0.99
432_E	436_S	0.884	0.99
191_T	267_E	0.883	0.99
316_A	382_L	0.883	0.99
14_K	131_H	0.879	0.99
446_E	451_L	0.876	0.99
439_V	445_E	0.876	0.99
458_D	465_D	0.874	0.99
173_P	201_G	0.871	0.99
268_R	321_E	0.868	0.99
439_V	457_V	0.865	0.99
224_T	269_F	0.864	0.99
16_A	20_R	0.861	0.99
49_R	53_V	0.860	0.99
363_V	381_V	0.859	0.99
113_N	116_E	0.856	0.99
274_A	334_I	0.853	0.99
272_V	315_I	0.852	0.99
402_E	418_G	0.852	0.99
398_H	401_D	0.851	0.99
359_V	394_V	0.851	0.99
313_M	317_E	0.850	0.99
243_H	247_G	0.848	0.99
176_V	205_E	0.847	0.99
80_D	83_Q	0.846	0.99
102_A	105_D	0.845	0.99
186_F	189_G	0.845	0.99
439_V	455_L	0.842	0.99
109_I	115_M	0.841	0.99
192_F	210_Y	0.841	0.99
439_V	456_Y	0.841	0.99
176_V	201_G	0.840	0.99
402_E	421_H	0.840	0.99
210_Y	221_L	0.839	0.99
440_G	444_I	0.838	0.99
450_N	456_Y	0.837	0.99
448_D	451_L	0.837	0.99
394_V	397_I	0.837	0.99
461_E	464_E	0.836	0.99
170_F	232_I	0.835	0.99
481_E	485_I	0.832	0.99
303_R	313_M	0.830	0.99
184_D	213_A	0.829	0.99
233_A	251_R	0.825	0.99
449_F	452_N	0.823	0.99
444_I	452_N	0.822	0.99
422_I	426_F	0.822	0.99
77_R	80_D	0.821	0.98
456_Y	459_T	0.820	0.98
285_D	288_Q	0.819	0.98
135_Y	139_R	0.817	0.98
270_D	329_G	0.816	0.98
87_N	94_N	0.815	0.98
308_D	336_I	0.814	0.98
458_D	462_P	0.813	0.98
445_E	454_A	0.813	0.98
286_D	289_D	0.812	0.98
321_E	329_G	0.809	0.98
437_R	457_V	0.804	0.98
54_E	57_G	0.802	0.98
367_E	373_N	0.802	0.98
450_N	455_L	0.801	0.98
440_G	456_Y	0.797	0.98
95_A	100_T	0.796	0.98
145_D	239_N	0.796	0.98
95_A	98_E	0.796	0.98
181_R	420_D	0.792	0.98
460_T	463_E	0.790	0.98
437_R	445_E	0.790	0.98
448_D	458_D	0.790	0.98
182_L	363_V	0.787	0.98
339_G	342_F	0.786	0.98
479_Q	485_I	0.785	0.98
394_V	399_A	0.785	0.98
396_F	399_A	0.784	0.98
454_A	460_T	0.783	0.98
361_A	426_F	0.781	0.98
52_I	56_Y	0.781	0.98
206_A	273_L	0.779	0.98
284_K	289_D	0.775	0.98
171_T	275_N	0.774	0.98
419_L	424_E	0.774	0.98
471_E	482_R	0.773	0.98
438_T	446_E	0.772	0.98
469_N	472_L	0.769	0.98
466_I	469_N	0.768	0.98
37_F	238_M	0.768	0.98
197_V	200_G	0.768	0.98
472_L	478_L	0.768	0.98
476_R	483_E	0.767	0.98
438_T	444_I	0.767	0.98
352_P	355_E	0.766	0.98
153_D	157_H	0.766	0.98
338_H	366_P	0.764	0.98
456_Y	460_T	0.761	0.98
11_H	14_K	0.760	0.98
291_Q	295_F	0.759	0.97
279_S	338_H	0.759	0.97
455_L	462_P	0.759	0.97
365_L	368_N	0.758	0.97
364_G	453_I	0.756	0.97
88_V	95_A	0.754	0.97
14_K	18_I	0.754	0.97
301_L	305_D	0.753	0.97
451_L	455_L	0.752	0.97
91_A	99_F	0.750	0.97
254_S	314_H	0.748	0.97
336_I	340_V	0.747	0.97
454_A	459_T	0.747	0.97
439_V	442_E	0.746	0.97
240_L	249_I	0.746	0.97
111_N	118_G	0.740	0.97
394_V	398_H	0.739	0.97
444_I	447_N	0.739	0.97
340_V	380_L	0.738	0.97
329_G	383_N	0.737	0.97
372_N	375_I	0.735	0.97
24_D	229_N	0.733	0.97
446_E	450_N	0.730	0.97
183_V	273_L	0.728	0.97
312_I	349_Y	0.728	0.97
183_V	331_K	0.727	0.97
278_F	377_S	0.725	0.97
177_Q	208_K	0.724	0.97
46_E	49_R	0.721	0.97
43_D	46_E	0.721	0.97
452_N	465_D	0.721	0.97
110_F	115_M	0.720	0.97
182_L	381_V	0.719	0.97
445_E	456_Y	0.718	0.96
74_E	78_W	0.715	0.96
444_I	450_N	0.712	0.96
191_T	270_D	0.710	0.96
455_L	460_T	0.706	0.96
17_D	20_R	0.706	0.96
369_L	375_I	0.704	0.96
428_D	431_T	0.704	0.96
392_G	396_F	0.704	0.96
89_D	92_I	0.702	0.96
362_I	394_V	0.701	0.96
175_I	369_L	0.700	0.96
359_V	380_L	0.700	0.96
437_R	444_I	0.699	0.96
287_L	290_D	0.699	0.96
422_I	427_D	0.699	0.96
439_V	452_N	0.698	0.96
364_G	396_F	0.698	0.96
360_E	381_V	0.698	0.96
474_E	485_I	0.698	0.96
449_F	454_A	0.694	0.96
53_V	57_G	0.689	0.96
471_E	479_Q	0.688	0.96
337_P	376_P	0.688	0.96
368_N	372_N	0.687	0.96
448_D	455_L	0.687	0.96
293_G	296_D	0.686	0.95
13_F	157_H	0.686	0.95
425_N	432_E	0.683	0.95
18_I	131_H	0.682	0.95
448_D	456_Y	0.682	0.95
365_L	377_S	0.681	0.95
40_A	44_E	0.680	0.95
24_D	27_D	0.680	0.95
446_E	454_A	0.678	0.95
63_N	67_Y	0.678	0.95
460_T	465_D	0.675	0.95
452_N	458_D	0.672	0.95
456_Y	462_P	0.672	0.95
456_Y	465_D	0.671	0.95
156_R	160_E	0.671	0.95
437_R	441_I	0.670	0.95
477_E	485_I	0.670	0.95
97_T	100_T	0.670	0.95
62_D	68_D	0.669	0.95
445_E	448_D	0.668	0.95
407_E	411_Q	0.667	0.95
395_Q	398_H	0.667	0.95
440_G	446_E	0.666	0.95
393_E	429_W	0.666	0.95
193_H	226_Q	0.665	0.95
340_V	378_A	0.657	0.94
179_C	202_M	0.657	0.94
339_G	354_L	0.657	0.94
438_T	452_N	0.655	0.94
87_N	93_N	0.654	0.94
296_D	300_K	0.650	0.94
84_E	91_A	0.648	0.94
406_E	415_T	0.648	0.94
191_T	320_K	0.646	0.94
207_A	218_P	0.646	0.94
474_E	481_E	0.645	0.94
351_Q	445_E	0.645	0.94
444_I	451_L	0.644	0.94
419_L	426_F	0.644	0.94
443_E	447_N	0.644	0.94
252_G	259_G	0.644	0.94
334_I	382_L	0.642	0.94
393_E	396_F	0.640	0.93
143_P	146_M	0.640	0.93
13_F	16_A	0.640	0.93
13_F	20_R	0.637	0.93
421_H	435_V	0.637	0.93
459_T	464_E	0.636	0.93
439_V	450_N	0.635	0.93
63_N	66_L	0.635	0.93
76_H	98_E	0.634	0.93
474_E	479_Q	0.632	0.93
12_L	150_A	0.632	0.93
185_D	190_M	0.630	0.93
474_E	482_R	0.630	0.93
408_L	411_Q	0.630	0.93
312_I	353_M	0.630	0.93
84_E	87_N	0.630	0.93
178_L	423_V	0.630	0.93
365_L	370_F	0.627	0.93
42_S	46_E	0.626	0.93
441_I	452_N	0.626	0.93
71_I	78_W	0.625	0.93
416_D	419_L	0.619	0.92
16_A	19_I	0.619	0.92
450_N	458_D	0.618	0.92
471_E	477_E	0.617	0.92
202_M	273_L	0.615	0.92
338_H	374_S	0.612	0.92
177_Q	212_E	0.610	0.92
416_D	423_V	0.610	0.92
437_R	452_N	0.608	0.92
21_D	25_P	0.604	0.91
416_D	424_E	0.604	0.91
313_M	352_P	0.604	0.91
166_G	229_N	0.603	0.91
366_P	373_N	0.603	0.91
338_H	367_E	0.602	0.91
94_N	98_E	0.601	0.91
474_E	483_E	0.600	0.91
69_V	77_R	0.599	0.91
313_M	316_A	0.599	0.91
456_Y	464_E	0.597	0.91
181_R	427_D	0.595	0.91
335_V	374_S	0.595	0.91
38_Y	81_L	0.595	0.91
69_V	73_P	0.594	0.91
106_L	116_E	0.592	0.91
457_V	479_Q	0.589	0.90
15_C	128_L	0.588	0.90
144_P	149_E	0.588	0.90
338_H	346_E	0.587	0.90
66_L	70_P	0.586	0.90
208_K	211_R	0.586	0.90
290_D	294_R	0.586	0.90
337_P	343_R	0.585	0.90
313_M	349_Y	0.583	0.90
279_S	308_D	0.583	0.90
71_I	74_E	0.583	0.90
288_Q	291_Q	0.582	0.90
56_Y	66_L	0.581	0.90
181_R	212_E	0.581	0.90
70_P	74_E	0.580	0.90
448_D	457_V	0.580	0.90
308_D	339_G	0.578	0.90
76_H	80_D	0.578	0.90
397_I	402_E	0.576	0.89
429_W	434_R	0.576	0.89
104_P	107_S	0.576	0.89
165_S	229_N	0.575	0.89
316_A	384_T	0.575	0.89
467_D	474_E	0.575	0.89
364_G	376_P	0.575	0.89
203_L	223_F	0.575	0.89
238_M	242_L	0.574	0.89
459_T	465_D	0.574	0.89
455_L	463_E	0.573	0.89
366_P	376_P	0.573	0.89
436_S	439_V	0.572	0.89
302_P	305_D	0.571	0.89
219_S	222_T	0.571	0.89
230_P	251_R	0.570	0.89
313_M	334_I	0.570	0.89
47_Q	51_E	0.570	0.89
475_L	483_E	0.569	0.89
463_E	467_D	0.569	0.89
421_H	426_F	0.568	0.89
437_R	454_A	0.567	0.89
70_P	76_H	0.567	0.89
416_D	421_H	0.565	0.88
372_N	376_P	0.564	0.88
191_T	222_T	0.564	0.88
371_Q	374_S	0.562	0.88
439_V	449_F	0.562	0.88
75_G	79_N	0.562	0.88
164_K	169_F	0.561	0.88
362_I	378_A	0.559	0.88
43_D	170_F	0.558	0.88
51_E	54_E	0.558	0.88
70_P	78_W	0.556	0.88
439_V	458_D	0.555	0.88
441_I	446_E	0.555	0.88
443_E	451_L	0.554	0.87
450_N	460_T	0.553	0.87
455_L	459_T	0.553	0.87
50_E	53_V	0.552	0.87
466_I	479_Q	0.548	0.87
106_L	115_M	0.548	0.87
250_E	253_D	0.548	0.87
68_D	72_V	0.548	0.87
189_G	270_D	0.547	0.87
38_Y	42_S	0.547	0.87
452_N	462_P	0.547	0.87
360_E	429_W	0.544	0.87
446_E	458_D	0.544	0.87
437_R	456_Y	0.544	0.87
272_V	332_A	0.544	0.87
315_I	319_L	0.543	0.86
176_V	180_V	0.542	0.86
420_D	423_V	0.541	0.86
306_R	337_P	0.541	0.86
48_E	52_I	0.541	0.86
99_F	102_A	0.540	0.86
51_E	56_Y	0.539	0.86
448_D	454_A	0.538	0.86
473_A	484_E	0.537	0.86
84_E	126_I	0.536	0.86
155_V	235_I	0.536	0.86
39_K	133_S	0.535	0.86
465_D	468_V	0.535	0.86
112_A	115_M	0.535	0.86
319_L	384_T	0.535	0.86
156_R	166_G	0.535	0.86
464_E	467_D	0.534	0.86
282_W	307_G	0.533	0.85
338_H	368_N	0.532	0.85
27_D	116_E	0.531	0.85
280_A	310_A	0.531	0.85
306_R	340_V	0.529	0.85
440_G	457_V	0.528	0.85
51_E	55_E	0.526	0.85
16_A	28_Y	0.525	0.85
439_V	447_N	0.525	0.85
70_P	73_P	0.524	0.84
339_G	373_N	0.524	0.84
107_S	110_F	0.523	0.84
465_D	471_E	0.523	0.84
173_P	205_E	0.522	0.84
31_Y	34_P	0.521	0.84
195_P	272_V	0.521	0.84
472_L	475_L	0.519	0.84
440_G	447_N	0.518	0.84
191_T	268_R	0.518	0.84
53_V	58_E	0.517	0.84
460_T	466_I	0.516	0.84
425_N	436_S	0.516	0.84
460_T	464_E	0.516	0.84
244_T	247_G	0.515	0.83
437_R	453_I	0.515	0.83
371_Q	375_I	0.514	0.83
471_E	485_I	0.514	0.83
170_F	274_A	0.514	0.83
447_N	458_D	0.511	0.83
309_Y	345_H	0.510	0.83
308_D	346_E	0.510	0.83
173_P	208_K	0.510	0.83
232_I	235_I	0.509	0.83
339_G	374_S	0.509	0.83
337_P	373_N	0.506	0.82
364_G	378_A	0.505	0.82
443_E	450_N	0.505	0.82
337_P	377_S	0.504	0.82
337_P	372_N	0.504	0.82
437_R	442_E	0.503	0.82
209_Y	213_A	0.503	0.82
225_G	249_I	0.503	0.82
470_E	473_A	0.503	0.82
458_D	468_V	0.502	0.82
373_N	378_A	0.502	0.82
34_P	42_S	0.501	0.82
339_G	366_P	0.501	0.82
393_E	398_H	0.500	0.82
191_T	221_L	0.500	0.82

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3lkdA	1	0.8677	100	0.261	Contact Map
3khkA	1	0.8597	100	0.304	Contact Map
2ar0A	1	0.8196	100	0.305	Contact Map
3ufbA	1	0.8737	100	0.323	Contact Map
2okcA	1	0.8176	100	0.373	Contact Map
3s1sA	1	0.9118	100	0.531	Contact Map
2f8lA	1	0.6353	100	0.555	Contact Map
2ih2A	1	0.5511	100	0.672	Contact Map
3v97A	1	0.8016	99.9	0.758	Contact Map
3lduA	1	0.6152	99.8	0.808	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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