Q9HSR7 - HALSA - GREMLIN Contacts

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Q9HSR7 - Type I restriction modification enzyme, R subunit

UniProt:	Q9HSR7	Sequences: MPVHTPDRAMSSLPSEQGVETSLLSWLDGLGWETHGLDGSQGASVLDERYSRSTADVIYWDLLAEQAIALNDAVTEDNVDRLVSSLKLDLDTDDLLAGNREFYAILTKGKQFQIDGEDGTEYVYVDLIDFADIERNRFHAVNQFSVSRGTTIRPDVNLFVNGIPLVTMELKSLAQDNDYYDAISDLHNYEETVPRLFVPGLFNVAADTTALRYGAVGAPTQFYMKWADAPEQYESDNEMRQAVQALCNPATLLDICKRFVFYDQRAGGDAKIVPRYMQYYAVTRLLDRVREGEPHPDPDERGHLDRGLVWHTQGSGKSFTMLYAAENLLSQDILDTPQVFLIVDTDKLASQMRDTLSNIGFEQSVVAESIDHLQELIEQGRSEVVLTTIQKFQDVEPNTQGNDEVVVMSDEAHRFMEKDLGSRLDAALPGCFHFGFTGTPVREGDEKSDRNTFDEFSPEGEEYLHRYSVKEGIEDGLILPVYFRLRHQMEWNVDEAGLDEEFEQQFAGLTTEEKREFIRESVTSRELAELEPRVETVVDEIDTHFDGVDKNGWKGMVVTPSRKSAAMYGERLMERRSEDEIEVLYTATSDDSDLIQQFHTENEERDQIVKQFNDEDEPKLLVVHNMLLTGFDAPNLKTMYLDRNLKNHNLMQAIARTNRVAEGKENGEIVDFQGVFENIDDALDYDPETQEYAARDREELFAELETQLDFVLDIFEDIPMDDSQEAIDQCLARVSTHPEKRKFKQGFRRLQNLYESVSPDGRLAQAGIQDDYKWLARVYTAFQRHHNRKDRPEDAMREKTRDIIEEHVDVGEIKRDFPVYELGQGHLEAIEDMDPATAATNVAHATREHLQPKTGQNPKYKRLSERVNDIVEEWEQGDRSDPEAVEALTEVEEEVLTVEAQAGDQAKAQAEFAIYTHLTEETPAAVDSEDEAQAIAADIVDEFEERIDRGYPGWEANETTVQTLEVVLLDALLKDHDRPALAKDDAFLDAVRGYLVENYV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	1000 (862)
Sequences:	3833 (2816)
Seq/√Len:	95.9

ECOLI - T1RK
HALSA - Q9HSR7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
20_E	143_Q	5.935	1.00
569_G	573_M	5.059	1.00
160_V	165_L	4.721	1.00
571_R	574_E	4.534	1.00
66_Q	69_A	4.465	1.00
555_G	620_L	4.273	1.00
540_E	672_F	4.154	1.00
280_Y	465_H	3.969	1.00
372_H	376_L	3.802	1.00
204_V	247_C	3.722	1.00
607_Q	611_Q	3.667	1.00
534_V	571_R	3.558	1.00
166_V	252_L	3.546	1.00
144_F	159_F	3.524	1.00
145_S	153_R	3.403	1.00
23_L	243_V	3.352	1.00
32_W	158_L	3.310	1.00
24_L	34_T	3.189	1.00
129_D	135_R	3.161	1.00
571_R	575_R	3.148	1.00
372_H	375_E	3.049	1.00
531_E	567_M	2.937	1.00
254_D	258_R	2.885	1.00
569_G	622_V	2.840	1.00
535_E	571_R	2.838	1.00
24_L	142_N	2.809	1.00
254_D	283_T	2.749	1.00
699_E	702_A	2.749	1.00
145_S	151_T	2.724	1.00
287_D	291_E	2.723	1.00
865_E	869_D	2.576	1.00
24_L	156_V	2.559	1.00
571_R	576_R	2.509	1.00
609_V	612_F	2.479	1.00
62_L	139_H	2.474	1.00
166_V	247_C	2.470	1.00
604_E	607_Q	2.468	1.00
27_L	158_L	2.396	1.00
141_V	144_F	2.392	1.00
843_A	847_R	2.389	1.00
772_Y	776_A	2.387	1.00
182_A	205_A	2.379	1.00
64_A	80_D	2.334	1.00
535_E	574_E	2.331	1.00
24_L	140_A	2.313	1.00
246_L	255_I	2.305	1.00
539_D	575_R	2.293	1.00
140_A	156_V	2.284	1.00
34_T	142_N	2.264	1.00
486_R	540_E	2.259	1.00
605_R	611_Q	2.247	1.00
571_R	577_S	2.238	1.00
33_E	137_R	2.226	1.00
736_T	739_E	2.209	1.00
605_R	608_I	2.206	1.00
202_F	273_V	2.196	1.00
605_R	613_N	2.189	1.00
605_R	612_F	2.165	1.00
883_E	887_A	2.149	1.00
597_Q	601_E	2.144	1.00
711_V	715_F	2.139	1.00
397_P	400_Q	2.120	1.00
284_R	465_H	2.113	1.00
884_A	888_L	2.106	1.00
677_E	681_D	2.101	1.00
595_I	601_E	2.100	1.00
342_I	387_T	2.093	1.00
17_Q	21_T	2.085	1.00
489_M	493_V	2.075	1.00
869_D	873_E	2.075	1.00
240_R	244_Q	2.064	1.00
64_A	68_I	2.053	1.00
58_I	163_I	2.045	1.00
602_N	605_R	2.044	1.00
281_A	320_T	2.024	1.00
840_T	843_A	2.016	1.00
536_T	539_D	2.014	1.00
570_E	574_E	2.013	1.00
737_H	740_K	2.012	1.00
143_Q	153_R	2.003	1.00
596_Q	601_E	1.999	1.00
318_S	355_T	1.999	1.00
20_E	142_N	1.997	1.00
601_E	604_E	1.997	1.00
609_V	613_N	1.980	1.00
146_V	157_N	1.978	1.00
129_D	132_D	1.977	1.00
531_E	535_E	1.976	1.00
287_D	290_R	1.972	1.00
861_K	865_E	1.971	1.00
132_D	135_R	1.971	1.00
25_S	28_D	1.963	1.00
828_E	832_D	1.959	1.00
99_N	102_F	1.958	1.00
23_L	168_M	1.958	1.00
259_F	283_T	1.945	1.00
350_S	606_D	1.943	1.00
772_Y	775_L	1.941	1.00
607_Q	613_N	1.935	1.00
489_M	492_N	1.923	1.00
56_D	60_W	1.913	1.00
533_R	537_V	1.910	1.00
605_R	609_V	1.908	1.00
556_M	636_L	1.907	1.00
823_G	826_H	1.895	1.00
165_L	252_L	1.866	1.00
472_G	478_I	1.857	1.00
884_A	887_A	1.847	1.00
322_L	355_T	1.839	1.00
371_D	375_E	1.836	1.00
826_H	830_I	1.823	1.00
597_Q	600_T	1.812	1.00
21_T	25_S	1.806	1.00
350_S	354_D	1.790	1.00
887_A	890_E	1.789	1.00
361_F	364_S	1.784	1.00
572_L	576_R	1.784	1.00
900_A	903_G	1.781	1.00
595_I	598_F	1.779	1.00
569_G	581_I	1.772	1.00
284_R	287_D	1.758	1.00
158_L	166_V	1.741	1.00
628_L	653_A	1.737	1.00
849_H	853_K	1.733	1.00
771_D	775_L	1.728	1.00
68_I	76_E	1.727	1.00
689_T	692_Y	1.709	1.00
93_D	97_A	1.705	1.00
723_S	734_V	1.705	1.00
595_I	600_T	1.704	1.00
889_T	893_E	1.703	1.00
20_E	153_R	1.694	1.00
676_F	680_D	1.690	1.00
362_E	366_V	1.675	1.00
27_L	247_C	1.672	1.00
62_L	137_R	1.665	1.00
263_D	272_I	1.662	1.00
886_E	890_E	1.649	1.00
118_D	121_E	1.649	1.00
15_S	18_G	1.634	1.00
533_R	642_D	1.633	1.00
65_E	69_A	1.630	1.00
607_Q	610_K	1.627	1.00
412_A	435_G	1.624	1.00
77_D	80_D	1.621	1.00
699_E	703_E	1.614	1.00
573_M	581_I	1.596	1.00
868_N	872_E	1.583	1.00
62_L	66_Q	1.576	1.00
555_G	640_Y	1.569	1.00
35_H	40_S	1.564	1.00
697_R	704_L	1.564	1.00
839_A	847_R	1.563	1.00
873_E	876_Q	1.563	1.00
598_F	601_E	1.560	1.00
538_V	572_L	1.553	1.00
157_N	167_T	1.552	1.00
712_L	771_D	1.549	1.00
463_Y	466_R	1.547	1.00
23_L	156_V	1.545	1.00
693_A	696_D	1.534	1.00
883_E	886_E	1.526	1.00
36_G	39_G	1.524	1.00
490_E	493_V	1.522	1.00
724_Q	728_D	1.520	1.00
147_S	151_T	1.510	1.00
730_C	734_V	1.508	1.00
104_A	108_K	1.505	1.00
772_Y	779_Y	1.501	1.00
701_F	705_E	1.501	1.00
872_E	876_Q	1.495	1.00
539_D	543_T	1.495	1.00
601_E	605_R	1.488	1.00
840_T	844_H	1.484	1.00
103_Y	107_T	1.481	1.00
368_E	372_H	1.481	1.00
874_W	877_G	1.475	1.00
326_E	330_S	1.471	1.00
99_N	103_Y	1.467	1.00
186_L	203_N	1.464	1.00
689_T	693_A	1.463	1.00
607_Q	612_F	1.454	1.00
400_Q	405_V	1.450	1.00
282_V	324_A	1.450	1.00
67_A	79_V	1.447	1.00
531_E	571_R	1.441	1.00
471_E	474_E	1.438	1.00
887_A	891_V	1.437	1.00
738_P	742_K	1.434	1.00
362_E	365_V	1.434	1.00
146_V	152_I	1.434	1.00
288_R	291_E	1.430	1.00
306_R	432_F	1.429	1.00
774_W	778_V	1.426	1.00
325_A	339_V	1.425	1.00
595_I	599_H	1.423	1.00
470_K	474_E	1.421	1.00
166_V	202_F	1.418	0.99
134_E	249_P	1.402	0.99
842_V	849_H	1.398	0.99
860_Y	863_L	1.396	0.99
558_V	643_R	1.394	0.99
367_A	376_L	1.392	0.99
369_S	391_K	1.388	0.99
111_Q	124_Y	1.384	0.99
346_D	350_S	1.379	0.99
202_F	213_Y	1.376	0.99
81_R	85_S	1.373	0.99
885_V	888_L	1.372	0.99
890_E	894_E	1.365	0.99
538_V	571_R	1.364	0.99
213_Y	246_L	1.363	0.99
742_K	746_G	1.356	0.99
726_A	729_Q	1.351	0.99
360_G	364_S	1.350	0.99
116_G	119_G	1.348	0.99
711_V	714_I	1.343	0.99
894_E	897_T	1.338	0.99
60_W	64_A	1.334	0.99
100_R	104_A	1.333	0.99
891_V	895_V	1.327	0.99
828_E	831_E	1.325	0.99
826_H	829_A	1.325	0.99
726_A	734_V	1.320	0.99
201_L	260_V	1.318	0.99
849_H	852_P	1.314	0.99
453_F	462_E	1.311	0.99
869_D	872_E	1.309	0.99
106_L	109_G	1.308	0.99
896_L	899_E	1.300	0.99
857_N	916_T	1.297	0.99
604_E	613_N	1.297	0.99
363_Q	366_V	1.294	0.99
559_T	565_A	1.292	0.99
608_I	613_N	1.288	0.99
854_T	857_N	1.288	0.99
604_E	611_Q	1.287	0.99
538_V	575_R	1.281	0.99
603_E	612_F	1.279	0.99
172_S	175_Q	1.279	0.99
740_K	743_F	1.278	0.99
342_I	392_F	1.276	0.99
565_A	624_H	1.276	0.99
423_R	426_A	1.274	0.99
611_Q	616_D	1.273	0.99
27_L	140_A	1.269	0.99
116_G	121_E	1.268	0.99
867_V	870_I	1.265	0.99
897_T	900_A	1.263	0.99
703_E	707_Q	1.258	0.99
283_T	327_N	1.257	0.99
839_A	858_P	1.255	0.99
739_E	742_K	1.254	0.99
503_E	506_F	1.253	0.99
819_V	826_H	1.251	0.99
596_Q	600_T	1.251	0.99
75_T	78_N	1.247	0.99
541_I	545_F	1.247	0.99
714_I	719_P	1.246	0.99
842_V	845_A	1.243	0.99
870_I	873_E	1.241	0.99
611_Q	614_D	1.239	0.99
891_V	899_E	1.239	0.99
313_Q	651_M	1.238	0.99
60_W	87_K	1.236	0.99
289_V	324_A	1.235	0.99
728_D	734_V	1.230	0.99
367_A	385_V	1.225	0.99
897_T	901_Q	1.220	0.98
289_V	434_F	1.220	0.98
692_Y	695_R	1.219	0.98
604_E	609_V	1.218	0.98
700_L	703_E	1.216	0.98
37_L	40_S	1.216	0.98
572_L	622_V	1.216	0.98
847_R	850_L	1.215	0.98
908_A	911_E	1.210	0.98
37_L	141_V	1.203	0.98
731_L	734_V	1.202	0.98
723_S	727_I	1.200	0.98
498_L	501_E	1.198	0.98
572_L	581_I	1.196	0.98
532_P	536_T	1.196	0.98
705_E	709_D	1.196	0.98
602_N	606_D	1.196	0.98
779_Y	783_Q	1.190	0.98
183_I	205_A	1.189	0.98
613_N	633_A	1.184	0.98
288_R	292_G	1.184	0.98
98_G	102_F	1.181	0.98
715_F	721_D	1.179	0.98
728_D	732_A	1.178	0.98
909_Q	912_F	1.178	0.98
887_A	901_Q	1.175	0.98
535_E	575_R	1.169	0.98
701_F	707_Q	1.167	0.98
836_A	840_T	1.167	0.98
544_H	547_G	1.165	0.98
313_Q	655_A	1.164	0.98
66_Q	71_N	1.163	0.98
912_F	916_T	1.162	0.98
887_A	892_E	1.159	0.98
514_K	517_F	1.159	0.98
272_I	319_F	1.157	0.98
175_Q	181_D	1.157	0.98
776_A	780_T	1.156	0.98
534_V	537_V	1.155	0.98
880_S	883_E	1.152	0.98
840_T	851_Q	1.150	0.98
211_L	242_A	1.147	0.98
59_Y	62_L	1.146	0.98
573_M	577_S	1.145	0.98
890_E	893_E	1.144	0.98
895_V	901_Q	1.143	0.98
251_T	279_Y	1.142	0.98
34_T	37_L	1.142	0.98
158_L	168_M	1.142	0.98
715_F	719_P	1.141	0.98
276_Y	471_E	1.138	0.98
80_D	84_S	1.138	0.98
865_E	868_N	1.137	0.98
820_Y	823_G	1.136	0.98
773_K	777_R	1.135	0.98
28_D	34_T	1.135	0.98
318_S	352_M	1.134	0.98
819_V	827_L	1.134	0.98
729_Q	733_R	1.134	0.98
798_E	813_I	1.134	0.98
27_L	165_L	1.133	0.98
771_D	774_W	1.130	0.97
822_L	829_A	1.124	0.97
77_D	81_R	1.123	0.97
15_S	19_V	1.121	0.97
697_R	701_F	1.120	0.97
689_T	694_A	1.118	0.97
128_I	165_L	1.115	0.97
723_S	726_A	1.115	0.97
840_T	847_R	1.115	0.97
805_E	808_V	1.111	0.97
158_L	247_C	1.111	0.97
819_V	823_G	1.110	0.97
83_V	87_K	1.110	0.97
280_Y	471_E	1.110	0.97
847_R	851_Q	1.108	0.97
215_A	218_A	1.108	0.97
529_E	564_S	1.107	0.97
65_E	68_I	1.105	0.97
289_V	292_G	1.105	0.97
862_R	866_R	1.102	0.97
608_I	611_Q	1.102	0.97
864_S	868_N	1.101	0.97
340_F	407_V	1.101	0.97
898_V	902_A	1.100	0.97
340_F	377_I	1.100	0.97
532_P	535_E	1.098	0.97
821_E	826_H	1.095	0.97
179_Y	205_A	1.094	0.97
698_E	702_A	1.093	0.97
609_V	627_L	1.092	0.97
876_Q	880_S	1.091	0.97
537_V	541_I	1.090	0.97
892_E	895_V	1.089	0.97
839_A	850_L	1.087	0.97
893_E	897_T	1.087	0.97
416_M	421_G	1.085	0.97
866_R	894_E	1.083	0.97
502_F	506_F	1.083	0.97
886_E	889_T	1.082	0.97
874_W	879_R	1.082	0.97
717_D	720_M	1.082	0.97
887_A	893_E	1.080	0.97
873_E	877_G	1.080	0.97
279_Y	283_T	1.078	0.97
160_V	252_L	1.077	0.97
496_A	500_E	1.074	0.97
89_D	93_D	1.073	0.97
601_E	613_N	1.073	0.97
343_V	349_A	1.072	0.97
870_I	879_R	1.069	0.96
34_T	140_A	1.068	0.96
884_A	892_E	1.068	0.96
824_Q	827_L	1.068	0.96
603_E	607_Q	1.067	0.96
884_A	891_V	1.066	0.96
850_L	853_K	1.066	0.96
355_T	359_I	1.066	0.96
258_R	330_S	1.063	0.96
134_E	250_A	1.062	0.96
559_T	568_Y	1.056	0.96
361_F	365_V	1.056	0.96
603_E	606_D	1.055	0.96
540_E	545_F	1.053	0.96
827_L	830_I	1.049	0.96
776_A	779_Y	1.049	0.96
181_D	184_S	1.047	0.96
898_V	901_Q	1.047	0.96
714_I	717_D	1.046	0.96
561_S	564_S	1.044	0.96
167_T	186_L	1.043	0.96
53_S	56_D	1.041	0.96
360_G	363_Q	1.040	0.96
568_Y	642_D	1.040	0.96
367_A	372_H	1.040	0.96
891_V	896_L	1.039	0.96
95_L	99_N	1.039	0.96
598_F	602_N	1.039	0.96
784_R	787_N	1.038	0.96
907_K	911_E	1.038	0.96
285_L	324_A	1.037	0.96
819_V	822_L	1.035	0.96
35_H	139_H	1.033	0.96
76_E	80_D	1.033	0.96
839_A	843_A	1.032	0.96
686_D	689_T	1.029	0.96
94_D	97_A	1.028	0.96
563_K	567_M	1.028	0.96
625_N	649_N	1.028	0.96
396_E	399_T	1.027	0.96
79_V	83_V	1.026	0.96
887_A	897_T	1.026	0.96
507_A	510_T	1.025	0.96
708_L	712_L	1.025	0.96
154_P	196_L	1.024	0.96
214_G	221_Q	1.023	0.95
863_L	870_I	1.019	0.95
97_A	100_R	1.019	0.95
318_S	343_V	1.018	0.95
887_A	895_V	1.016	0.95
654_I	671_D	1.016	0.95
604_E	608_I	1.012	0.95
152_I	192_T	1.009	0.95
686_D	690_Q	1.008	0.95
715_F	718_I	1.007	0.95
254_D	327_N	1.007	0.95
170_L	206_A	1.004	0.95
691_E	694_A	1.003	0.95
541_I	557_V	1.003	0.95
56_D	59_Y	1.002	0.95
562_R	599_H	1.002	0.95
21_T	142_N	1.001	0.95
557_V	622_V	1.000	0.95
778_V	782_F	0.998	0.95
160_V	256_C	0.998	0.95
882_P	886_E	0.996	0.95
724_Q	727_I	0.995	0.95
179_Y	212_R	0.995	0.95
747_F	775_L	0.994	0.95
820_Y	824_Q	0.992	0.95
822_L	827_L	0.990	0.95
101_E	104_A	0.989	0.95
538_V	545_F	0.989	0.95
700_L	707_Q	0.989	0.95
899_E	903_G	0.988	0.95
695_R	699_E	0.987	0.95
892_E	896_L	0.987	0.95
387_T	391_K	0.987	0.95
286_L	327_N	0.984	0.94
840_T	850_L	0.983	0.94
508_G	511_T	0.981	0.94
99_N	106_L	0.981	0.94
575_R	578_E	0.981	0.94
102_F	106_L	0.980	0.94
700_L	705_E	0.977	0.94
496_A	499_D	0.976	0.94
248_N	251_T	0.975	0.94
654_I	669_I	0.973	0.94
361_F	366_V	0.973	0.94
837_T	842_V	0.972	0.94
243_V	247_C	0.972	0.94
716_E	720_M	0.971	0.94
888_L	891_V	0.970	0.94
714_I	718_I	0.970	0.94
52_R	56_D	0.970	0.94
184_S	188_N	0.969	0.94
167_T	200_G	0.969	0.94
873_E	887_A	0.968	0.94
892_E	903_G	0.966	0.94
723_S	731_L	0.966	0.94
102_F	107_T	0.966	0.94
822_L	830_I	0.965	0.94
605_R	626_M	0.965	0.94
138_F	253_L	0.963	0.94
533_R	541_I	0.962	0.94
126_D	131_A	0.961	0.94
545_F	620_L	0.959	0.94
678_N	681_D	0.958	0.94
501_E	504_Q	0.958	0.94
341_L	352_M	0.957	0.94
866_R	869_D	0.957	0.94
246_L	251_T	0.955	0.93
889_T	895_V	0.954	0.93
390_Q	420_L	0.953	0.93
64_A	76_E	0.952	0.93
690_Q	694_A	0.952	0.93
725_E	728_D	0.949	0.93
572_L	578_E	0.948	0.93
204_V	242_A	0.948	0.93
737_H	741_R	0.947	0.93
743_F	747_F	0.947	0.93
732_A	735_S	0.946	0.93
255_I	279_Y	0.946	0.93
775_L	778_V	0.945	0.93
602_N	607_Q	0.945	0.93
534_V	564_S	0.944	0.93
842_V	847_R	0.942	0.93
798_E	801_R	0.941	0.93
699_E	707_Q	0.941	0.93
425_D	433_H	0.940	0.93
86_L	90_L	0.937	0.93
588_T	594_L	0.936	0.93
713_D	717_D	0.936	0.93
730_C	733_R	0.936	0.93
280_Y	284_R	0.935	0.93
146_V	154_P	0.933	0.93
565_A	622_V	0.932	0.93
827_L	831_E	0.929	0.93
115_D	118_D	0.929	0.93
802_D	813_I	0.929	0.93
342_I	424_L	0.927	0.92
594_L	601_E	0.925	0.92
490_E	537_V	0.924	0.92
829_A	832_D	0.922	0.92
32_W	249_P	0.922	0.92
853_K	857_N	0.922	0.92
602_N	612_F	0.920	0.92
515_R	518_I	0.920	0.92
887_A	903_G	0.917	0.92
703_E	706_T	0.915	0.92
139_H	159_F	0.911	0.92
81_R	112_F	0.911	0.92
601_E	612_F	0.911	0.92
775_L	780_T	0.908	0.92
152_I	193_V	0.908	0.92
538_V	581_I	0.905	0.92
494_D	497_G	0.903	0.91
538_V	542_D	0.901	0.91
840_T	845_A	0.901	0.91
534_V	568_Y	0.901	0.91
394_D	399_T	0.900	0.91
600_T	604_E	0.900	0.91
770_D	775_L	0.898	0.91
707_Q	710_F	0.897	0.91
63_L	71_N	0.896	0.91
621_L	627_L	0.894	0.91
802_D	808_V	0.893	0.91
228_D	245_A	0.893	0.91
690_Q	693_A	0.892	0.91
596_Q	599_H	0.890	0.91
724_Q	730_C	0.888	0.91
206_A	239_M	0.888	0.91
608_I	612_F	0.888	0.91
777_R	781_A	0.887	0.91
708_L	768_I	0.885	0.91
826_H	831_E	0.884	0.91
26_W	244_Q	0.883	0.91
560_P	564_S	0.883	0.91
906_A	910_A	0.881	0.90
390_Q	415_F	0.879	0.90
891_V	903_G	0.879	0.90
785_H	789_K	0.879	0.90
542_D	546_D	0.878	0.90
641_L	645_L	0.877	0.90
16_E	19_V	0.873	0.90
839_A	851_Q	0.872	0.90
96_L	99_N	0.872	0.90
594_L	597_Q	0.872	0.90
311_H	320_T	0.871	0.90
594_L	598_F	0.870	0.90
557_V	620_L	0.869	0.90
821_E	829_A	0.868	0.90
882_P	888_L	0.866	0.90
876_Q	881_D	0.866	0.90
124_Y	128_I	0.866	0.90
600_T	603_E	0.865	0.90
840_T	858_P	0.864	0.90
160_V	253_L	0.863	0.89
794_D	797_R	0.862	0.89
860_Y	866_R	0.862	0.89
696_D	699_E	0.861	0.89
836_A	847_R	0.861	0.89
741_R	745_Q	0.861	0.89
306_R	457_S	0.860	0.89
774_W	779_Y	0.858	0.89
525_R	529_E	0.857	0.89
885_V	892_E	0.853	0.89
697_R	708_L	0.853	0.89
96_L	201_L	0.853	0.89
78_N	82_L	0.852	0.89
572_L	577_S	0.851	0.89
651_M	655_A	0.851	0.89
883_E	891_V	0.850	0.89
37_L	41_Q	0.850	0.89
888_L	893_E	0.849	0.89
206_A	211_L	0.849	0.89
848_E	852_P	0.848	0.89
422_S	426_A	0.847	0.89
603_E	613_N	0.846	0.89
546_D	637_K	0.845	0.88
237_N	240_R	0.843	0.88
711_V	716_E	0.843	0.88
855_G	858_P	0.843	0.88
840_T	849_H	0.842	0.88
553_W	637_K	0.842	0.88
501_E	506_F	0.841	0.88
889_T	892_E	0.840	0.88
853_K	858_P	0.840	0.88
772_Y	778_V	0.837	0.88
158_L	249_P	0.837	0.88
820_Y	826_H	0.837	0.88
843_A	853_K	0.836	0.88
883_E	890_E	0.834	0.88
128_I	132_D	0.834	0.88
702_A	705_E	0.833	0.88
867_V	872_E	0.832	0.88
470_K	480_P	0.832	0.88
349_A	388_T	0.832	0.88
35_H	38_D	0.831	0.88
567_M	570_E	0.830	0.88
707_Q	715_F	0.830	0.88
771_D	777_R	0.829	0.88
787_N	790_D	0.829	0.88
574_E	578_E	0.827	0.87
59_Y	67_A	0.827	0.87
78_N	81_R	0.826	0.87
790_D	793_E	0.826	0.87
888_L	892_E	0.825	0.87
825_G	829_A	0.823	0.87
774_W	782_F	0.823	0.87
777_R	780_T	0.822	0.87
710_F	715_F	0.822	0.87
53_S	57_V	0.821	0.87
107_T	112_F	0.821	0.87
52_R	55_A	0.817	0.87
852_P	855_G	0.815	0.87
184_S	187_H	0.814	0.87
845_A	849_H	0.814	0.87
891_V	894_E	0.814	0.87
718_I	721_D	0.813	0.86
581_I	620_L	0.813	0.86
713_D	716_E	0.812	0.86
537_V	540_E	0.810	0.86
534_V	567_M	0.809	0.86
821_E	824_Q	0.808	0.86
16_E	20_E	0.807	0.86
740_K	744_K	0.806	0.86
81_R	84_S	0.806	0.86
819_V	824_Q	0.806	0.86
822_L	831_E	0.805	0.86
726_A	730_C	0.805	0.86
712_L	716_E	0.804	0.86
66_Q	70_L	0.804	0.86
156_V	170_L	0.803	0.86
324_A	434_F	0.802	0.86
703_E	709_D	0.802	0.86
899_E	902_A	0.801	0.86
897_T	903_G	0.800	0.86
255_I	274_P	0.799	0.86
710_F	713_D	0.799	0.86
654_I	679_I	0.799	0.86
534_V	541_I	0.797	0.85
901_Q	916_T	0.794	0.85
829_A	833_M	0.794	0.85
261_F	359_I	0.794	0.85
580_E	617_E	0.794	0.85
834_D	851_Q	0.793	0.85
846_T	850_L	0.793	0.85
165_L	256_C	0.792	0.85
822_L	826_H	0.792	0.85
677_E	680_D	0.790	0.85
254_D	279_Y	0.790	0.85
54_T	59_Y	0.789	0.85
824_Q	828_E	0.787	0.85
257_K	260_V	0.785	0.85
854_T	858_P	0.785	0.85
821_E	827_L	0.785	0.85
883_E	892_E	0.784	0.84
499_D	506_F	0.784	0.84
729_Q	732_A	0.783	0.84
777_R	782_F	0.783	0.84
506_F	517_F	0.783	0.84
892_E	901_Q	0.783	0.84
610_K	614_D	0.782	0.84
802_D	806_E	0.782	0.84
680_D	683_L	0.782	0.84
602_N	608_I	0.779	0.84
801_R	805_E	0.777	0.84
212_R	225_K	0.777	0.84
850_L	858_P	0.777	0.84
308_L	452_T	0.776	0.84
862_R	865_E	0.776	0.84
773_K	776_A	0.775	0.84
870_I	877_G	0.775	0.84
70_L	126_D	0.774	0.84
58_I	63_L	0.773	0.84
836_A	849_H	0.772	0.84
598_F	605_R	0.772	0.84
728_D	731_L	0.772	0.84
562_R	566_A	0.772	0.84
704_L	707_Q	0.771	0.83
76_E	375_E	0.771	0.83
54_T	58_I	0.770	0.83
57_V	60_W	0.770	0.83
393_Q	399_T	0.769	0.83
136_N	140_A	0.769	0.83
841_N	845_A	0.768	0.83
830_I	833_M	0.768	0.83
835_P	840_T	0.767	0.83
814_K	817_F	0.766	0.83
893_E	903_G	0.764	0.83
708_L	771_D	0.764	0.83
845_A	853_K	0.764	0.83
736_T	743_F	0.763	0.83
58_I	86_L	0.763	0.83
370_I	374_Q	0.761	0.83
340_F	387_T	0.761	0.83
516_E	519_R	0.760	0.83
896_L	900_A	0.760	0.83
138_F	160_V	0.759	0.82
772_Y	780_T	0.759	0.82
910_A	913_A	0.759	0.82
215_A	273_V	0.759	0.82
368_E	391_K	0.758	0.82
618_P	621_L	0.758	0.82
374_Q	378_E	0.757	0.82
38_D	41_Q	0.757	0.82
727_I	731_L	0.757	0.82
794_D	799_K	0.757	0.82
843_A	850_L	0.756	0.82
387_T	846_T	0.756	0.82
318_S	322_L	0.755	0.82
394_D	397_P	0.754	0.82
138_F	252_L	0.754	0.82
775_L	779_Y	0.753	0.82
265_R	270_A	0.753	0.82
697_R	700_L	0.752	0.82
700_L	708_L	0.752	0.82
32_W	252_L	0.752	0.82
740_K	781_A	0.751	0.82
863_L	874_W	0.750	0.82
895_V	898_V	0.750	0.82
502_F	505_Q	0.750	0.82
704_L	708_L	0.748	0.82
15_S	22_S	0.747	0.81
863_L	875_E	0.747	0.81
538_V	541_I	0.745	0.81
67_A	86_L	0.745	0.81
727_I	730_C	0.744	0.81
709_D	713_D	0.744	0.81
810_V	816_D	0.743	0.81
409_S	435_G	0.743	0.81
887_A	899_E	0.742	0.81
907_K	910_A	0.742	0.81
415_F	456_F	0.741	0.81
281_A	309_V	0.741	0.81
824_Q	832_D	0.741	0.81
86_L	103_Y	0.740	0.81
82_L	86_L	0.739	0.81
353_R	386_L	0.738	0.81
891_V	900_A	0.737	0.81
128_I	160_V	0.736	0.81
67_A	78_N	0.735	0.80
288_R	307_G	0.735	0.80
651_M	682_A	0.735	0.80
896_L	901_Q	0.735	0.80
343_V	386_L	0.734	0.80
27_L	249_P	0.733	0.80
820_Y	825_G	0.733	0.80
393_Q	396_E	0.733	0.80
282_V	327_N	0.733	0.80
851_Q	858_P	0.732	0.80
117_E	121_E	0.731	0.80
813_I	816_D	0.731	0.80
353_R	357_S	0.730	0.80
178_D	181_D	0.730	0.80
500_E	503_E	0.729	0.80
866_R	870_I	0.729	0.80
206_A	242_A	0.729	0.80
839_A	846_T	0.728	0.80
35_H	39_G	0.728	0.80
866_R	871_V	0.728	0.80
129_D	133_I	0.727	0.80
261_F	319_F	0.726	0.80
895_V	899_E	0.726	0.80
715_F	720_M	0.726	0.80
98_G	103_Y	0.726	0.80
26_W	29_G	0.725	0.80
724_Q	733_R	0.723	0.79
136_N	141_V	0.723	0.79
820_Y	827_L	0.722	0.79
911_E	914_I	0.722	0.79
603_E	611_Q	0.722	0.79
737_H	744_K	0.722	0.79
534_V	538_V	0.718	0.79
96_L	100_R	0.718	0.79
601_E	611_Q	0.717	0.79
698_E	703_E	0.717	0.79
700_L	704_L	0.716	0.79
64_A	79_V	0.716	0.79
834_D	837_T	0.715	0.79
499_D	864_S	0.715	0.79
35_H	141_V	0.715	0.79
875_E	878_D	0.714	0.78
870_I	874_W	0.714	0.78
202_F	252_L	0.713	0.78
55_A	59_Y	0.713	0.78
312_T	478_I	0.712	0.78
691_E	696_D	0.711	0.78
812_E	816_D	0.708	0.78
712_L	718_I	0.708	0.78
544_H	640_Y	0.708	0.78
745_Q	749_R	0.708	0.78
533_R	545_F	0.707	0.78
175_Q	178_D	0.706	0.78
121_E	125_V	0.704	0.78
819_V	830_I	0.703	0.77
100_R	106_L	0.703	0.77
16_E	22_S	0.703	0.77
914_I	917_H	0.703	0.77
604_E	612_F	0.702	0.77
603_E	609_V	0.702	0.77
751_Q	754_Y	0.702	0.77
837_T	841_N	0.701	0.77
54_T	57_V	0.701	0.77
835_P	838_A	0.701	0.77
572_L	575_R	0.700	0.77
506_F	514_K	0.700	0.77
834_D	838_A	0.699	0.77
707_Q	749_R	0.697	0.77
884_A	893_E	0.697	0.77
702_A	706_T	0.697	0.77
768_I	778_V	0.696	0.77
877_G	880_S	0.696	0.77
407_V	428_L	0.695	0.77
556_M	621_L	0.695	0.77
33_E	139_H	0.695	0.77
415_F	418_K	0.695	0.77
867_V	871_V	0.695	0.77
801_R	804_I	0.695	0.77
870_I	876_Q	0.694	0.77
558_V	653_A	0.694	0.77
686_D	693_A	0.693	0.76
729_Q	734_V	0.693	0.76
27_L	32_W	0.691	0.76
596_Q	602_N	0.691	0.76
523_T	527_L	0.690	0.76
840_T	857_N	0.690	0.76
331_Q	335_D	0.690	0.76
133_I	250_A	0.690	0.76
396_E	400_Q	0.690	0.76
722_D	734_V	0.690	0.76
723_S	735_S	0.689	0.76
887_A	900_A	0.687	0.76
863_L	866_R	0.686	0.76
837_T	850_L	0.686	0.76
821_E	830_I	0.685	0.76
247_C	252_L	0.684	0.75
895_V	900_A	0.683	0.75
30_L	248_N	0.683	0.75
27_L	166_V	0.683	0.75
74_V	125_V	0.682	0.75
692_Y	696_D	0.682	0.75
602_N	609_V	0.682	0.75
367_A	391_K	0.681	0.75
276_Y	465_H	0.681	0.75
129_D	134_E	0.679	0.75
699_E	708_L	0.679	0.75
55_A	67_A	0.678	0.75
96_L	102_F	0.677	0.75
754_Y	758_S	0.675	0.75
800_T	813_I	0.675	0.75
420_L	423_R	0.675	0.75
320_T	436_F	0.674	0.74
874_W	878_D	0.674	0.74
825_G	828_E	0.674	0.74
839_A	849_H	0.673	0.74
557_V	572_L	0.673	0.74
274_P	282_V	0.673	0.74
600_T	605_R	0.672	0.74
313_Q	478_I	0.672	0.74
836_A	841_N	0.671	0.74
847_R	853_K	0.671	0.74
884_A	903_G	0.670	0.74
844_H	854_T	0.669	0.74
133_I	253_L	0.669	0.74
594_L	599_H	0.668	0.74
557_V	568_Y	0.668	0.74
887_A	896_L	0.668	0.74
19_V	23_L	0.667	0.74
369_S	372_H	0.667	0.74
499_D	505_Q	0.666	0.74
502_F	509_L	0.665	0.73
68_I	71_N	0.665	0.73
647_N	678_N	0.664	0.73
883_E	888_L	0.664	0.73
614_D	619_K	0.663	0.73
180_Y	220_T	0.663	0.73
125_V	132_D	0.663	0.73
741_R	744_K	0.663	0.73
19_V	239_M	0.663	0.73
714_I	720_M	0.662	0.73
25_S	29_G	0.661	0.73
311_H	315_S	0.659	0.73
407_V	433_H	0.659	0.73
725_E	730_C	0.658	0.73
29_G	38_D	0.656	0.72
571_R	578_E	0.656	0.72
701_F	708_L	0.655	0.72
276_Y	475_D	0.654	0.72
203_N	223_Y	0.654	0.72
877_G	881_D	0.654	0.72
75_T	114_I	0.654	0.72
823_G	830_I	0.654	0.72
594_L	604_E	0.654	0.72
894_E	899_E	0.653	0.72
895_V	903_G	0.653	0.72
821_E	825_G	0.653	0.72
869_D	876_Q	0.652	0.72
838_A	842_V	0.652	0.72
510_T	513_E	0.652	0.72
736_T	740_K	0.651	0.72
195_R	198_V	0.651	0.72
183_I	212_R	0.651	0.72
69_A	72_D	0.651	0.72
543_T	547_G	0.650	0.72
562_R	601_E	0.650	0.72
722_D	725_E	0.649	0.72
904_D	910_A	0.648	0.71
515_R	519_R	0.647	0.71
890_E	902_A	0.647	0.71
100_R	103_Y	0.647	0.71
750_L	754_Y	0.647	0.71
703_E	708_L	0.646	0.71
635_N	661_A	0.646	0.71
566_A	595_I	0.645	0.71
789_K	792_P	0.645	0.71
360_G	366_V	0.643	0.71
350_S	610_K	0.642	0.71
824_Q	833_M	0.642	0.71
595_I	604_E	0.641	0.71
701_F	709_D	0.641	0.71
194_P	197_F	0.640	0.71
908_A	913_A	0.640	0.71
20_E	24_L	0.640	0.71
69_A	135_R	0.640	0.71
597_Q	602_N	0.639	0.70
503_E	514_K	0.638	0.70
185_D	625_N	0.638	0.70
697_R	707_Q	0.637	0.70
871_V	874_W	0.635	0.70
706_T	710_F	0.634	0.70
61_D	65_E	0.634	0.70
313_Q	463_Y	0.634	0.70
693_A	708_L	0.634	0.70
897_T	902_A	0.633	0.70
548_V	637_K	0.633	0.70
324_A	328_L	0.633	0.70
746_G	749_R	0.632	0.70
874_W	880_S	0.632	0.70
315_S	648_H	0.632	0.70
58_I	87_K	0.632	0.70
142_N	153_R	0.631	0.69
16_E	170_L	0.630	0.69
498_L	506_F	0.629	0.69
102_F	105_I	0.628	0.69
883_E	900_A	0.628	0.69
441_V	451_N	0.627	0.69
306_R	434_F	0.627	0.69
507_A	511_T	0.627	0.69
601_E	607_Q	0.626	0.69
144_F	157_N	0.626	0.69
75_T	79_V	0.626	0.69
185_D	472_G	0.626	0.69
52_R	58_I	0.625	0.69
103_Y	106_L	0.625	0.69
561_S	624_H	0.625	0.69
390_Q	424_L	0.624	0.69
845_A	848_E	0.624	0.69
891_V	901_Q	0.624	0.69
883_E	889_T	0.622	0.68
540_E	543_T	0.622	0.68
711_V	718_I	0.622	0.68
554_K	612_F	0.622	0.68
531_E	570_E	0.622	0.68
776_A	784_R	0.621	0.68
671_D	674_G	0.621	0.68
891_V	898_V	0.621	0.68
189_Y	192_T	0.620	0.68
902_A	917_H	0.620	0.68
876_Q	879_R	0.620	0.68
340_F	405_V	0.620	0.68
80_D	681_D	0.619	0.68
797_R	800_T	0.619	0.68
823_G	831_E	0.619	0.68
883_E	899_E	0.618	0.68
376_L	385_V	0.618	0.68
754_Y	757_V	0.617	0.68
711_V	720_M	0.617	0.68
908_A	912_F	0.616	0.68
85_S	703_E	0.616	0.68
285_L	464_L	0.616	0.68
861_K	867_V	0.616	0.68
524_S	528_A	0.616	0.68
152_I	589_S	0.616	0.68
888_L	901_Q	0.616	0.68
606_D	609_V	0.615	0.68
871_V	875_E	0.615	0.68
69_A	73_A	0.614	0.67
158_L	250_A	0.614	0.67
165_L	378_E	0.613	0.67
680_D	684_D	0.611	0.67
768_I	771_D	0.611	0.67
438_G	667_G	0.611	0.67
839_A	853_K	0.611	0.67
506_F	509_L	0.610	0.67
885_V	889_T	0.610	0.67
771_D	778_V	0.610	0.67
870_I	878_D	0.609	0.67
157_N	164_P	0.609	0.67
602_N	613_N	0.608	0.67
535_E	539_D	0.607	0.67
58_I	62_L	0.607	0.67
838_A	845_A	0.606	0.66
717_D	721_D	0.606	0.66
274_P	323_Y	0.606	0.66
75_T	117_E	0.605	0.66
32_W	40_S	0.605	0.66
24_L	28_D	0.605	0.66
883_E	893_E	0.604	0.66
529_E	561_S	0.603	0.66
724_Q	734_V	0.603	0.66
893_E	899_E	0.603	0.66
228_D	231_E	0.601	0.66
515_R	620_L	0.601	0.66
901_Q	912_F	0.600	0.66
834_D	841_N	0.600	0.66
712_L	720_M	0.600	0.66
94_D	99_N	0.599	0.65
772_Y	782_F	0.598	0.65
74_V	79_V	0.598	0.65
892_E	900_A	0.597	0.65
843_A	849_H	0.597	0.65
599_H	604_E	0.596	0.65
867_V	879_R	0.596	0.65
704_L	715_F	0.595	0.65
533_R	538_V	0.595	0.65
710_F	714_I	0.595	0.65
443_E	450_R	0.595	0.65
156_V	168_M	0.594	0.65
883_E	896_L	0.594	0.65
573_M	576_R	0.593	0.65
202_F	246_L	0.593	0.65
873_E	890_E	0.593	0.65
94_D	100_R	0.593	0.65
213_Y	273_V	0.592	0.65
285_L	434_F	0.592	0.65
813_I	817_F	0.592	0.65
438_G	650_L	0.592	0.65
213_Y	216_V	0.590	0.64
760_D	763_L	0.590	0.64
468_S	471_E	0.590	0.64
481_V	639_M	0.589	0.64
803_I	807_H	0.589	0.64
868_N	875_E	0.588	0.64
155_D	171_K	0.586	0.64
112_F	127_L	0.586	0.64
768_I	772_Y	0.585	0.64
540_E	544_H	0.585	0.64
62_L	65_E	0.584	0.64
524_S	529_E	0.584	0.64
884_A	901_Q	0.584	0.64
318_S	359_I	0.583	0.63
888_L	897_T	0.583	0.63
180_Y	184_S	0.583	0.63
529_E	534_V	0.583	0.63
882_P	895_V	0.582	0.63
878_D	881_D	0.581	0.63
731_L	735_S	0.581	0.63
152_I	188_N	0.581	0.63
606_D	613_N	0.581	0.63
694_A	700_L	0.581	0.63
851_Q	854_T	0.580	0.63
249_P	252_L	0.580	0.63
238_E	241_Q	0.579	0.63
36_G	340_F	0.577	0.63
888_L	900_A	0.577	0.63
601_E	609_V	0.577	0.63
913_A	917_H	0.576	0.62
826_H	833_M	0.575	0.62
594_L	607_Q	0.575	0.62
549_D	637_K	0.575	0.62
355_T	358_N	0.575	0.62
122_Y	405_V	0.574	0.62
836_A	839_A	0.574	0.62
770_D	774_W	0.573	0.62
538_V	568_Y	0.572	0.62
126_D	129_D	0.572	0.62
822_L	828_E	0.571	0.62
839_A	842_V	0.571	0.62
837_T	847_R	0.570	0.62
133_I	249_P	0.570	0.62
712_L	715_F	0.570	0.62
514_K	521_S	0.569	0.62
890_E	900_A	0.569	0.62
861_K	869_D	0.569	0.62
349_A	352_M	0.569	0.62
681_D	684_D	0.568	0.61
894_E	900_A	0.568	0.61
143_Q	146_V	0.567	0.61
509_L	512_E	0.567	0.61
874_W	881_D	0.566	0.61
884_A	895_V	0.566	0.61
698_E	701_F	0.566	0.61
867_V	876_Q	0.566	0.61
723_S	728_D	0.566	0.61
106_L	110_K	0.566	0.61
501_E	505_Q	0.566	0.61
537_V	545_F	0.565	0.61
693_A	697_R	0.565	0.61
229_A	232_Q	0.565	0.61
888_L	895_V	0.565	0.61
481_V	657_T	0.564	0.61
778_V	787_N	0.564	0.61
779_Y	784_R	0.563	0.61
227_A	474_E	0.563	0.61
637_K	667_G	0.562	0.61
775_L	786_H	0.562	0.61
200_G	203_N	0.561	0.60
123_V	129_D	0.561	0.60
33_E	39_G	0.561	0.60
596_Q	604_E	0.560	0.60
558_V	639_M	0.559	0.60
141_V	159_F	0.559	0.60
290_R	331_Q	0.559	0.60
861_K	864_S	0.559	0.60
18_G	21_T	0.559	0.60
866_R	873_E	0.559	0.60
85_S	89_D	0.559	0.60
800_T	803_I	0.559	0.60
600_T	612_F	0.558	0.60
536_T	540_E	0.558	0.60
882_P	885_V	0.558	0.60
834_D	853_K	0.558	0.60
318_S	416_M	0.558	0.60
508_G	512_E	0.558	0.60
909_Q	913_A	0.557	0.60
21_T	24_L	0.557	0.60
554_K	633_A	0.556	0.60
883_E	897_T	0.554	0.60
490_E	497_G	0.554	0.60
26_W	240_R	0.554	0.60
744_K	782_F	0.554	0.60
788_R	793_E	0.553	0.59
248_N	252_L	0.553	0.59
534_V	540_E	0.552	0.59
60_W	79_V	0.552	0.59
674_G	677_E	0.552	0.59
811_G	817_F	0.552	0.59
170_L	277_M	0.551	0.59
757_V	763_L	0.551	0.59
310_W	667_G	0.551	0.59
633_A	636_L	0.551	0.59
193_V	196_L	0.550	0.59
32_W	36_G	0.550	0.59
57_V	61_D	0.550	0.59
769_Q	772_Y	0.548	0.59
850_L	857_N	0.547	0.59
105_I	108_K	0.547	0.59
556_M	620_L	0.546	0.58
32_W	160_V	0.545	0.58
723_S	733_R	0.545	0.58
727_I	734_V	0.545	0.58
163_I	199_P	0.545	0.58
313_Q	624_H	0.544	0.58
796_M	807_H	0.543	0.58
836_A	851_Q	0.543	0.58
870_I	884_A	0.543	0.58
478_I	639_M	0.543	0.58
56_D	70_L	0.541	0.58
467_Y	475_D	0.540	0.58
85_S	105_I	0.540	0.58
893_E	896_L	0.540	0.58
770_D	773_K	0.540	0.58
697_R	711_V	0.539	0.57
722_D	727_I	0.539	0.57
846_T	879_R	0.539	0.57
711_V	717_D	0.538	0.57
482_Y	666_N	0.538	0.57
846_T	849_H	0.538	0.57
489_M	494_D	0.537	0.57
19_V	170_L	0.536	0.57
130_F	134_E	0.536	0.57
313_Q	650_L	0.535	0.57
389_I	424_L	0.535	0.57
539_D	578_E	0.535	0.57
63_L	66_Q	0.534	0.57
68_I	79_V	0.534	0.57
835_P	842_V	0.534	0.57
154_P	648_H	0.534	0.57
105_I	109_G	0.533	0.57
312_T	438_G	0.532	0.56
843_A	855_G	0.532	0.56
519_R	522_V	0.532	0.56
823_G	827_L	0.532	0.56
867_V	878_D	0.531	0.56
573_M	622_V	0.531	0.56
650_L	667_G	0.530	0.56
341_L	356_L	0.530	0.56
636_L	657_T	0.530	0.56
80_D	83_V	0.530	0.56
18_G	22_S	0.529	0.56
744_K	747_F	0.529	0.56
844_H	852_P	0.529	0.56
505_Q	512_E	0.529	0.56
724_Q	731_L	0.528	0.56
890_E	897_T	0.528	0.56
835_P	843_A	0.527	0.56
710_F	746_G	0.527	0.56
528_A	564_S	0.527	0.56
811_G	814_K	0.527	0.56
606_D	611_Q	0.527	0.56
289_V	432_F	0.527	0.56
566_A	570_E	0.526	0.56
502_F	508_G	0.525	0.55
86_L	127_L	0.525	0.55
826_H	832_D	0.523	0.55
839_A	844_H	0.522	0.55
479_L	662_E	0.522	0.55
251_T	254_D	0.522	0.55
58_I	64_A	0.521	0.55
100_R	264_Q	0.521	0.55
490_E	494_D	0.521	0.55
597_Q	603_E	0.521	0.55
66_Q	137_R	0.520	0.55
861_K	866_R	0.520	0.55
863_L	867_V	0.520	0.55
178_D	210_A	0.520	0.55
768_I	775_L	0.520	0.55
441_V	648_H	0.519	0.55
206_A	626_M	0.519	0.55
310_W	438_G	0.519	0.55
835_P	839_A	0.519	0.55
144_F	196_L	0.518	0.55
492_N	495_E	0.518	0.55
669_I	719_P	0.518	0.55
20_E	145_S	0.518	0.55
896_L	903_G	0.517	0.54
507_A	512_E	0.517	0.54
887_A	902_A	0.516	0.54
884_A	899_E	0.516	0.54
691_E	695_R	0.516	0.54
873_E	878_D	0.515	0.54
41_Q	52_R	0.515	0.54
222_F	275_R	0.515	0.54
778_V	781_A	0.514	0.54
20_E	189_Y	0.513	0.54
98_G	101_E	0.513	0.54
582_E	618_P	0.513	0.54
904_D	908_A	0.513	0.54
723_S	730_C	0.513	0.54
908_A	914_I	0.512	0.54
59_Y	82_L	0.512	0.54
853_K	856_Q	0.512	0.54
885_V	895_V	0.511	0.54
798_E	804_I	0.511	0.54
549_D	552_G	0.510	0.53
17_Q	25_S	0.509	0.53
701_F	711_V	0.509	0.53
709_D	712_L	0.509	0.53
330_S	361_F	0.509	0.53
725_E	733_R	0.509	0.53
313_Q	558_V	0.509	0.53
548_V	551_N	0.509	0.53
705_E	708_L	0.508	0.53
407_V	431_C	0.507	0.53
842_V	853_K	0.507	0.53
837_T	857_N	0.507	0.53
30_L	249_P	0.506	0.53
277_M	352_M	0.506	0.53
530_L	536_T	0.505	0.53
799_K	804_I	0.505	0.53
844_H	848_E	0.505	0.53
839_A	855_G	0.505	0.53
331_Q	336_T	0.505	0.53
212_R	238_E	0.504	0.53
438_G	478_I	0.504	0.53
910_A	915_Y	0.504	0.53
85_S	91_D	0.503	0.52
867_V	874_W	0.503	0.52
55_A	63_L	0.503	0.52
82_L	87_K	0.502	0.52
148_R	151_T	0.502	0.52
256_C	557_V	0.501	0.52
28_D	249_P	0.500	0.52

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2w00A	1	0.734	100	0.453	Contact Map
3h1tA	1	0.473	100	0.68	Contact Map
2ocaA	1	0.474	100	0.831	Contact Map
2fwrA	1	0.414	100	0.855	Contact Map
4zcfC	1	0.478	100	0.857	Contact Map
3sqwA	1	0.468	100	0.858	Contact Map
3i5xA	1	0.459	100	0.859	Contact Map
3oiyA	1	0.36	100	0.864	Contact Map
1wp9A	1	0.378	100	0.868	Contact Map
1fuuA	2	0.361	100	0.87	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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