Q9HSQ8 - HALSA - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

Q9HSQ8 - Uncharacterized protein

UniProt:	Q9HSQ8	Sequences: MRWTVLVVAAFVVGAGCGGPPMAAQDPPSTPESGDAPMVTVVDADTGVEHGSVAVAVAATRGERYTGLSTRESLSADEGMLFVHERAGSRAYVMRSMAFPIDIIYVGADRNITSIHHATVPDGDGPLTRYEGHGKWVLEVSLNWTAAHNVSVGDRVRIPAAGE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	163 (129)
Sequences:	832 (670)
Seq/√Len:	59.0

HALSA - Q9HSQ8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
95_R	124_D	3.111	1.00
56_A	71_R	3.054	1.00
74_L	141_S	2.996	1.00
140_V	144_W	2.900	1.00
123_G	126_P	2.777	1.00
106_V	138_L	2.625	1.00
144_W	147_A	2.605	1.00
69_S	96_S	2.532	1.00
111_N	155_R	2.423	1.00
117_H	146_A	2.306	1.00
106_V	156_V	2.260	1.00
59_A	63_E	2.256	1.00
72_E	98_A	2.208	1.00
75_S	78_E	2.175	1.00
76_A	141_S	2.149	1.00
60_T	63_E	2.096	1.00
113_T	134_G	2.041	1.00
87_A	108_A	2.019	1.00
90_R	134_G	1.972	1.00
98_A	122_D	1.945	1.00
104_I	140_V	1.853	1.00
104_I	145_T	1.798	0.99
112_I	154_D	1.723	0.99
140_V	145_T	1.719	0.99
92_Y	103_I	1.698	0.99
53_V	144_W	1.670	0.99
114_S	131_E	1.604	0.99
127_L	130_Y	1.559	0.98
113_T	132_G	1.517	0.98
104_I	137_V	1.517	0.98
55_V	138_L	1.507	0.98
74_L	99_F	1.499	0.98
62_G	66_T	1.452	0.98
64_R	84_H	1.423	0.97
84_H	92_Y	1.412	0.97
46_T	49_E	1.406	0.97
144_W	148_H	1.331	0.96
130_Y	134_G	1.279	0.95
107_G	111_N	1.269	0.95
116_H	119_T	1.260	0.94
68_L	74_L	1.224	0.93
115_I	145_T	1.216	0.93
137_V	145_T	1.209	0.93
112_I	115_I	1.180	0.92
119_T	123_G	1.179	0.92
69_S	97_M	1.166	0.92
107_G	113_T	1.165	0.92
61_R	64_R	1.160	0.91
53_V	148_H	1.157	0.91
84_H	137_V	1.145	0.91
119_T	142_L	1.134	0.90
108_A	135_K	1.125	0.90
73_S	99_F	1.116	0.90
68_L	141_S	1.082	0.88
104_I	118_A	1.079	0.88
118_A	137_V	1.074	0.88
89_S	133_H	1.068	0.88
114_S	152_V	1.065	0.87
36_A	54_A	1.036	0.86
97_M	101_I	1.032	0.86
64_R	90_R	1.025	0.85
105_Y	114_S	1.022	0.85
99_F	141_S	0.997	0.84
76_A	147_A	0.988	0.83
120_V	123_G	0.987	0.83
84_H	90_R	0.986	0.83
118_A	142_L	0.981	0.83
72_E	99_F	0.975	0.82
102_D	117_H	0.966	0.82
54_A	77_D	0.959	0.81
117_H	145_T	0.957	0.81
102_D	142_L	0.955	0.81
124_D	127_L	0.955	0.81
123_G	128_T	0.935	0.80
141_S	147_A	0.934	0.80
106_V	112_I	0.922	0.79
74_L	78_E	0.919	0.78
102_D	137_V	0.918	0.78
104_I	150_V	0.917	0.78
104_I	112_I	0.911	0.78
117_H	142_L	0.908	0.78
35_D	38_M	0.898	0.77
101_I	143_N	0.889	0.76
74_L	79_G	0.876	0.75
103_I	137_V	0.869	0.74
99_F	142_L	0.865	0.74
122_D	130_Y	0.863	0.74
41_V	44_A	0.860	0.74
118_A	145_T	0.846	0.72
107_G	136_W	0.844	0.72
83_V	92_Y	0.835	0.71
114_S	130_Y	0.833	0.71
35_D	54_A	0.832	0.71
90_R	137_V	0.828	0.71
136_W	158_I	0.823	0.70
119_T	128_T	0.819	0.70
36_A	40_T	0.815	0.70
145_T	148_H	0.806	0.69
68_L	99_F	0.800	0.68
95_R	121_P	0.781	0.66
53_V	140_V	0.766	0.65
106_V	150_V	0.759	0.64
102_D	115_I	0.756	0.64
38_M	42_V	0.747	0.63
87_A	134_G	0.747	0.63
66_T	93_V	0.742	0.62
70_T	96_S	0.734	0.61
100_P	150_V	0.733	0.61
45_D	77_D	0.708	0.59
81_L	106_V	0.706	0.58
87_A	133_H	0.700	0.58
149_N	157_R	0.698	0.58
111_N	132_G	0.698	0.58
110_R	158_I	0.696	0.57
80_M	139_E	0.695	0.57
49_E	149_N	0.695	0.57
67_G	139_E	0.683	0.56
146_A	149_N	0.682	0.56
62_G	65_Y	0.681	0.56
30_T	87_A	0.667	0.54
111_N	152_V	0.664	0.54
93_V	97_M	0.661	0.54
55_V	79_G	0.659	0.53
65_Y	124_D	0.658	0.53
121_P	134_G	0.653	0.53
91_A	129_R	0.652	0.53
37_P	78_E	0.651	0.52
56_A	156_V	0.646	0.52
36_A	41_V	0.643	0.52
42_V	46_T	0.643	0.52
70_T	122_D	0.639	0.51
83_V	136_W	0.632	0.50
103_I	118_A	0.623	0.49
107_G	134_G	0.623	0.49
113_T	136_W	0.622	0.49
77_D	141_S	0.616	0.49
53_V	158_I	0.609	0.48
29_S	32_E	0.602	0.47
104_I	119_T	0.593	0.46
38_M	41_V	0.591	0.46
45_D	49_E	0.590	0.46
52_S	77_D	0.589	0.46
110_R	138_L	0.589	0.46
33_S	37_P	0.585	0.45
85_E	92_Y	0.583	0.45
81_L	138_L	0.582	0.45
54_A	78_E	0.579	0.44
118_A	129_R	0.578	0.44
37_P	55_V	0.575	0.44
42_V	89_S	0.571	0.44
103_I	138_L	0.571	0.44
118_A	159_P	0.570	0.43
121_P	128_T	0.570	0.43
75_S	115_I	0.567	0.43
92_Y	129_R	0.567	0.43
124_D	128_T	0.567	0.43
45_D	66_T	0.563	0.43
56_A	106_V	0.562	0.43
33_S	76_A	0.561	0.42
35_D	59_A	0.561	0.42
85_E	126_P	0.555	0.42
83_V	135_K	0.555	0.42
83_V	158_I	0.553	0.42
89_S	116_H	0.552	0.42
66_T	70_T	0.551	0.41
66_T	98_A	0.543	0.41
74_L	140_V	0.541	0.40
65_Y	151_S	0.541	0.40
114_S	132_G	0.538	0.40
128_T	144_W	0.534	0.40
72_E	97_M	0.534	0.40
50_H	157_R	0.532	0.39
31_P	47_G	0.528	0.39
103_I	114_S	0.526	0.39
55_V	128_T	0.526	0.39
29_S	72_E	0.525	0.39
51_G	144_W	0.525	0.39
60_T	85_E	0.525	0.39
92_Y	127_L	0.524	0.39
80_M	93_V	0.520	0.38
151_S	154_D	0.519	0.38
100_P	119_T	0.518	0.38
87_A	141_S	0.518	0.38
129_R	132_G	0.516	0.38
72_E	146_A	0.516	0.38
38_M	54_A	0.515	0.38
73_S	98_A	0.512	0.37
73_S	100_P	0.512	0.37
102_D	145_T	0.512	0.37
92_Y	104_I	0.509	0.37
57_V	158_I	0.508	0.37
50_H	156_V	0.504	0.36
85_E	151_S	0.503	0.36
123_G	127_L	0.500	0.36

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3pjyA	1	0.7914	100	0.276	Contact Map
3m7aA	1	0.8589	100	0.278	Contact Map
3k6vA	1	0.6135	35.8	0.938	Contact Map
3zbiC	1	0.1656	25.5	0.943	Contact Map
4r2fA	1	0.7362	23.9	0.943	Contact Map
2oa4A	1	0.4233	23.6	0.943	Contact Map
1yfbA	2	0.2577	20.8	0.945	Contact Map
3vxbA	1	0.7791	20	0.945	Contact Map
2jrtA	1	0.4172	18.9	0.946	Contact Map
4r9fA	1	0.773	18.4	0.946	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0064 seconds.