MUTL - HALSA - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

MUTL - DNA mismatch repair protein MutL

UniProt:	Q9HSM6	Sequences: MTDRIRALDDATVARIAAGEVVERPASVVKELVENSLDAGAASVDVSVDAGGTDRIVVADDGRGMTGDDLRMAVRQHTTSKLDDASGLDGVGTLGFRGEALYTIGSVAELTVTTRPRNAGDTGARITVDHGDAGSVAPAGHPAGTTVEVTDLFGETPARRKYLKRAATEFGHVNRAVTRYALANPDVAVSLTHDGREVFATTGTGDVQDAALAVYGREVAQSLRTVDADPAADSVERVHGYVSDPEVTRSTREYLATFVNGRAVTDAVLREAVLDGYGDQLAPDRYPFAVLFVDCEGVDANVHPRKLEVRFEDEAGVKAAVEAGVRDALLDAGLVRAGAPRGASKPGDAEISPEHSPTDRDAGAAGGGDAAGQSDGNGQRTAASGATSESPASAFETGGGDEAADSAASTDGTRERPGSGTESRTGRFDAPAENARLPTGAGGPEADDQDTTSERDSLPDLRVLGQLHDTYVVAEAGDGLVLVDQHAADERVHYERLQARVDGASQALVAPAELELTAGEAAVFEAALGGLRELGFDAELAGRTARVTAVPAVLADALDAELARDVLSSFLADADGTPVADAADAVLADLACSPAIKGNTSLAEGSVVALLDALDACENPYACPHGRPTIVEVDGDELAARFERDYPGHAGRRREDAGN	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	659 (610)
Sequences:	3407 (2719)
Seq/√Len:	110.1

ECOLI - MUTL
BACSU - MUTL
HALSA - MUTL

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
42_A	61_D	9.880	1.00
115_R	143_A	5.677	1.00
40_G	63_R	5.516	1.00
37_L	187_V	5.396	1.00
46_V	177_V	5.383	1.00
109_E	151_D	5.097	1.00
237_R	294_D	4.909	1.00
29_V	56_I	3.806	1.00
493_H	595_A	3.597	1.00
66_T	69_D	3.305	1.00
33_V	177_V	3.281	1.00
123_G	141_H	3.178	1.00
117_R	143_A	3.132	1.00
70_L	114_T	3.101	1.00
43_S	61_D	3.063	1.00
473_V	480_L	3.014	1.00
560_A	564_R	2.978	1.00
116_P	119_A	2.967	1.00
227_D	237_R	2.879	1.00
70_L	124_A	2.869	1.00
125_R	137_A	2.841	1.00
74_V	110_L	2.818	1.00
298_V	309_V	2.769	1.00
6_R	83_D	2.765	1.00
593_S	597_K	2.710	1.00
111_T	125_R	2.681	1.00
48_V	173_V	2.676	1.00
28_V	152_L	2.582	1.00
229_D	237_R	2.575	1.00
4_R	69_D	2.521	1.00
483_V	611_L	2.507	1.00
130_H	154_G	2.495	1.00
47_S	57_V	2.493	1.00
462_R	475_E	2.485	1.00
259_V	309_V	2.484	1.00
472_V	607_V	2.476	1.00
466_Q	485_Q	2.447	1.00
50_A	54_D	2.446	1.00
539_E	548_T	2.436	1.00
473_V	482_L	2.435	1.00
129_D	134_G	2.406	1.00
45_D	190_S	2.400	1.00
239_H	294_D	2.391	1.00
273_V	289_A	2.389	1.00
55_R	148_E	2.363	1.00
211_A	241_Y	2.344	1.00
109_E	129_D	2.340	1.00
65_M	70_L	2.307	1.00
623_C	627_R	2.298	1.00
49_D	55_R	2.190	1.00
609_A	613_A	2.186	1.00
71_R	136_V	2.180	1.00
257_T	273_V	2.139	1.00
113_T	125_R	2.079	1.00
9_D	12_T	2.072	1.00
53_T	166_A	2.070	1.00
592_C	625_H	2.056	1.00
55_R	150_T	2.052	1.00
30_K	34_E	2.012	1.00
463_V	472_V	2.010	1.00
72_M	78_T	2.005	1.00
505_S	549_A	1.998	1.00
57_V	146_T	1.994	1.00
313_D	316_G	1.986	1.00
44_V	187_V	1.966	1.00
520_E	571_L	1.961	1.00
111_T	150_T	1.960	1.00
537_D	549_A	1.955	1.00
227_D	239_H	1.946	1.00
226_V	242_V	1.945	1.00
28_V	56_I	1.920	1.00
72_M	75_R	1.915	1.00
513_E	544_T	1.913	1.00
608_V	612_D	1.899	1.00
113_T	139_A	1.895	1.00
592_C	623_C	1.894	1.00
226_V	291_L	1.873	1.00
273_V	325_V	1.869	1.00
596_I	602_L	1.867	1.00
114_T	124_A	1.846	1.00
464_L	480_L	1.837	1.00
170_F	193_H	1.825	1.00
170_F	198_V	1.805	1.00
47_S	59_A	1.800	1.00
7_A	75_R	1.797	1.00
73_A	101_L	1.787	1.00
532_R	537_D	1.785	1.00
201_T	210_A	1.784	1.00
206_D	209_D	1.771	1.00
215_Y	256_A	1.768	1.00
584_D	588_A	1.765	1.00
592_C	627_R	1.757	1.00
484_D	487_A	1.757	1.00
529_G	532_R	1.739	1.00
113_T	148_E	1.737	1.00
203_G	210_A	1.723	1.00
65_M	73_A	1.719	1.00
228_A	324_G	1.714	1.00
257_T	269_L	1.705	1.00
463_V	607_V	1.703	1.00
486_H	592_C	1.688	1.00
491_R	617_C	1.657	1.00
128_V	133_A	1.655	1.00
486_H	627_R	1.641	1.00
74_V	112_V	1.623	1.00
175_R	179_R	1.609	1.00
470_T	598_G	1.604	1.00
634_D	637_E	1.603	1.00
82_L	87_G	1.590	1.00
525_E	540_L	1.589	1.00
238_V	320_A	1.584	1.00
527_A	530_G	1.569	1.00
259_V	311_F	1.539	1.00
276_G	322_E	1.530	1.00
353_P	356_S	1.528	1.00
43_S	188_A	1.525	1.00
112_V	126_I	1.523	1.00
48_V	170_F	1.522	1.00
188_A	203_G	1.518	1.00
492_V	610_L	1.517	1.00
474_A	483_V	1.514	1.00
197_E	200_A	1.511	1.00
47_S	192_T	1.507	1.00
603_A	606_S	1.507	1.00
528_L	532_R	1.490	1.00
37_L	184_N	1.488	1.00
561_E	565_D	1.486	1.00
524_F	545_A	1.484	1.00
224_R	328_A	1.475	1.00
113_T	141_H	1.475	1.00
130_H	155_E	1.474	1.00
170_F	191_L	1.469	1.00
458_L	461_L	1.467	1.00
70_L	126_I	1.464	1.00
495_E	617_C	1.463	1.00
355_H	360_R	1.456	1.00
239_H	292_F	1.454	1.00
29_V	173_V	1.454	1.00
113_T	123_G	1.448	1.00
596_I	610_L	1.438	1.00
614_L	620_P	1.436	1.00
425_T	428_F	1.417	1.00
464_L	473_V	1.416	1.00
467_L	480_L	1.416	1.00
614_L	617_C	1.416	1.00
10_D	14_A	1.415	1.00
65_M	69_D	1.412	1.00
255_L	289_A	1.410	1.00
604_E	608_V	1.410	1.00
33_V	189_V	1.405	1.00
111_T	148_E	1.400	1.00
236_E	293_V	1.399	1.00
489_D	493_H	1.389	1.00
466_Q	602_L	1.379	1.00
613_A	616_A	1.377	1.00
486_H	625_H	1.377	1.00
487_A	490_E	1.375	1.00
517_T	520_E	1.356	1.00
67_G	119_A	1.353	1.00
486_H	490_E	1.351	1.00
65_M	71_R	1.344	1.00
425_T	429_D	1.344	1.00
368_G	371_A	1.344	1.00
228_A	320_A	1.343	1.00
70_L	112_V	1.343	1.00
491_R	495_E	1.341	1.00
583_A	587_L	1.340	1.00
490_E	623_C	1.326	1.00
414_R	417_P	1.320	0.99
483_V	488_A	1.318	0.99
37_L	94_L	1.312	0.99
486_H	623_C	1.308	0.99
94_L	261_G	1.307	0.99
410_T	413_T	1.305	0.99
490_E	625_H	1.303	0.99
73_A	112_V	1.296	0.99
486_H	489_D	1.295	0.99
588_A	591_A	1.288	0.99
168_T	172_H	1.286	0.99
363_G	366_G	1.280	0.99
485_Q	602_L	1.274	0.99
45_D	192_T	1.267	0.99
102_Y	106_S	1.265	0.99
248_T	285_R	1.261	0.99
123_G	140_G	1.258	0.99
479_G	632_E	1.257	0.99
568_S	572_A	1.251	0.99
490_E	592_C	1.248	0.99
190_S	200_A	1.243	0.99
28_V	149_V	1.235	0.99
467_L	473_V	1.231	0.99
275_D	322_E	1.230	0.99
4_R	66_T	1.227	0.99
58_V	147_V	1.221	0.99
411_D	415_E	1.216	0.99
421_T	424_R	1.212	0.99
547_V	563_A	1.204	0.99
74_V	128_V	1.202	0.99
496_R	613_A	1.199	0.99
472_V	485_Q	1.199	0.99
382_A	385_G	1.198	0.99
422_E	425_T	1.193	0.99
17_A	20_E	1.191	0.99
126_I	133_A	1.189	0.99
204_T	209_D	1.180	0.99
50_A	166_A	1.179	0.99
369_D	372_G	1.172	0.99
496_R	500_R	1.172	0.99
604_E	607_V	1.170	0.99
522_A	526_A	1.169	0.99
180_Y	189_V	1.164	0.99
520_E	564_R	1.155	0.99
420_G	423_S	1.154	0.99
177_V	189_V	1.146	0.99
466_Q	486_H	1.146	0.99
468_H	479_G	1.145	0.99
467_L	638_L	1.140	0.99
380_R	383_A	1.139	0.98
625_H	628_P	1.135	0.98
367_G	371_A	1.134	0.98
521_A	545_A	1.133	0.98
127_T	135_S	1.119	0.98
421_T	425_T	1.118	0.98
141_H	146_T	1.111	0.98
520_E	568_S	1.109	0.98
211_A	290_V	1.106	0.98
170_F	174_N	1.103	0.98
82_L	91_V	1.099	0.98
563_A	567_L	1.092	0.98
12_T	85_A	1.092	0.98
271_E	318_K	1.090	0.98
498_Q	587_L	1.086	0.98
362_A	365_A	1.086	0.98
10_D	132_D	1.080	0.98
28_V	32_L	1.079	0.98
622_A	629_T	1.078	0.98
359_D	367_G	1.076	0.98
270_R	289_A	1.074	0.98
243_S	247_V	1.074	0.98
29_V	33_V	1.073	0.98
493_H	496_R	1.073	0.98
464_L	467_L	1.070	0.98
353_P	358_T	1.070	0.98
410_T	414_R	1.068	0.98
417_P	423_S	1.068	0.98
90_G	296_E	1.068	0.98
461_L	474_A	1.067	0.98
208_Q	220_A	1.065	0.98
174_N	191_L	1.062	0.98
208_Q	241_Y	1.061	0.98
541_A	544_T	1.059	0.98
600_T	606_S	1.058	0.98
358_T	367_G	1.054	0.98
414_R	419_S	1.052	0.97
297_G	312_E	1.052	0.97
469_D	601_S	1.045	0.97
365_A	368_G	1.044	0.97
364_A	367_G	1.043	0.97
412_G	416_R	1.039	0.97
493_H	594_P	1.039	0.97
361_D	370_A	1.035	0.97
111_T	127_T	1.032	0.97
67_G	124_A	1.030	0.97
410_T	416_R	1.027	0.97
501_V	587_L	1.025	0.97
302_V	310_R	1.017	0.97
592_C	597_K	1.017	0.97
515_E	544_T	1.014	0.97
118_N	143_A	1.009	0.97
513_E	546_R	1.009	0.97
466_Q	607_V	1.006	0.97
368_G	372_G	1.003	0.97
261_G	294_D	0.997	0.97
67_G	136_V	0.997	0.97
365_A	374_S	0.995	0.96
256_A	263_A	0.993	0.96
96_F	306_K	0.993	0.96
516_L	524_F	0.991	0.96
105_G	126_I	0.991	0.96
226_V	240_G	0.990	0.96
11_A	15_R	0.989	0.96
499_A	503_G	0.989	0.96
53_T	163_L	0.988	0.96
530_G	533_E	0.988	0.96
20_E	25_P	0.988	0.96
188_A	200_A	0.987	0.96
366_G	372_G	0.986	0.96
240_G	291_L	0.982	0.96
293_V	320_A	0.980	0.96
415_E	418_G	0.976	0.96
349_A	352_S	0.976	0.96
436_R	439_T	0.976	0.96
230_P	320_A	0.971	0.96
359_D	365_A	0.964	0.96
323_A	327_D	0.961	0.96
445_E	449_Q	0.960	0.96
369_D	373_Q	0.959	0.96
379_Q	382_A	0.958	0.96
592_C	628_P	0.955	0.96
366_G	369_D	0.946	0.95
15_R	85_A	0.946	0.95
444_P	447_D	0.944	0.95
377_N	380_R	0.944	0.95
381_T	385_G	0.943	0.95
374_S	379_Q	0.943	0.95
580_A	583_A	0.943	0.95
469_D	599_N	0.941	0.95
416_R	420_G	0.941	0.95
266_D	314_E	0.941	0.95
378_G	382_A	0.939	0.95
279_D	622_A	0.939	0.95
365_A	370_A	0.939	0.95
354_E	358_T	0.937	0.95
116_P	143_A	0.935	0.95
54_D	151_D	0.933	0.95
175_R	178_T	0.931	0.95
365_A	369_D	0.929	0.95
370_A	373_Q	0.928	0.95
366_G	371_A	0.928	0.95
295_C	298_V	0.923	0.95
558_L	561_E	0.915	0.94
434_N	439_T	0.915	0.94
322_E	326_R	0.915	0.94
114_T	119_A	0.912	0.94
415_E	419_S	0.911	0.94
4_R	63_R	0.911	0.94
236_E	317_V	0.910	0.94
375_D	378_G	0.910	0.94
110_L	128_V	0.908	0.94
242_V	289_A	0.908	0.94
355_H	358_T	0.908	0.94
619_N	622_A	0.905	0.94
413_T	425_T	0.904	0.94
112_V	147_V	0.904	0.94
359_D	362_A	0.902	0.94
412_G	415_E	0.899	0.94
352_S	355_H	0.894	0.94
417_P	421_T	0.894	0.94
104_I	149_V	0.894	0.94
411_D	414_R	0.894	0.94
258_F	292_F	0.893	0.94
523_V	527_A	0.890	0.93
414_R	418_G	0.889	0.93
67_G	138_P	0.888	0.93
412_G	418_G	0.886	0.93
107_V	152_L	0.886	0.93
623_C	628_P	0.884	0.93
354_E	361_D	0.884	0.93
487_A	495_E	0.881	0.93
174_N	178_T	0.880	0.93
299_D	306_K	0.880	0.93
521_A	540_L	0.878	0.93
614_L	621_Y	0.878	0.93
516_L	567_L	0.878	0.93
243_S	288_F	0.874	0.93
490_E	627_R	0.872	0.93
65_M	68_D	0.872	0.93
529_G	533_E	0.872	0.93
499_A	618_E	0.872	0.93
468_H	635_G	0.871	0.93
36_S	40_G	0.870	0.93
356_S	359_D	0.868	0.93
460_D	463_V	0.868	0.93
115_R	121_D	0.865	0.93
351_I	354_E	0.865	0.93
621_Y	630_I	0.863	0.92
282_A	622_A	0.863	0.92
348_D	351_I	0.862	0.92
413_T	416_R	0.861	0.92
547_V	559_D	0.861	0.92
434_N	437_L	0.860	0.92
368_G	373_Q	0.860	0.92
326_R	330_L	0.859	0.92
96_F	99_E	0.859	0.92
437_L	441_A	0.857	0.92
414_R	421_T	0.857	0.92
297_G	313_D	0.856	0.92
224_R	242_V	0.856	0.92
361_D	372_G	0.855	0.92
349_A	353_P	0.855	0.92
327_D	331_D	0.852	0.92
419_S	423_S	0.851	0.92
472_V	486_H	0.851	0.92
352_S	358_T	0.850	0.92
66_T	116_P	0.850	0.92
444_P	448_D	0.848	0.92
485_Q	490_E	0.847	0.92
236_E	320_A	0.846	0.92
350_E	353_P	0.841	0.91
494_Y	498_Q	0.838	0.91
592_C	596_I	0.837	0.91
413_T	418_G	0.837	0.91
367_G	373_Q	0.836	0.91
435_A	439_T	0.835	0.91
366_G	370_A	0.835	0.91
71_R	133_A	0.835	0.91
11_A	293_V	0.835	0.91
282_A	285_R	0.834	0.91
229_D	235_V	0.833	0.91
471_Y	486_H	0.831	0.91
358_T	361_D	0.831	0.91
489_D	597_K	0.829	0.91
243_S	248_T	0.828	0.91
484_D	489_D	0.827	0.91
507_A	549_A	0.824	0.91
165_R	168_T	0.824	0.91
16_I	20_E	0.824	0.91
470_T	484_D	0.821	0.90
486_H	495_E	0.820	0.90
487_A	627_R	0.819	0.90
76_Q	114_T	0.819	0.90
361_D	383_A	0.819	0.90
362_A	367_G	0.819	0.90
252_R	274_L	0.817	0.90
65_M	116_P	0.817	0.90
597_K	625_H	0.816	0.90
360_R	364_A	0.816	0.90
476_A	479_G	0.816	0.90
151_D	154_G	0.816	0.90
21_V	52_G	0.815	0.90
45_D	59_A	0.814	0.90
18_A	25_P	0.813	0.90
376_G	381_T	0.813	0.90
418_G	421_T	0.813	0.90
370_A	378_G	0.811	0.90
265_T	307_L	0.809	0.90
418_G	425_T	0.809	0.90
257_T	270_R	0.809	0.90
96_F	299_D	0.807	0.90
346_P	349_A	0.806	0.90
470_T	639_A	0.805	0.90
367_G	372_G	0.804	0.89
201_T	204_T	0.801	0.89
228_A	327_D	0.801	0.89
51_G	170_F	0.799	0.89
524_F	567_L	0.799	0.89
96_F	100_A	0.798	0.89
589_D	593_S	0.795	0.89
33_V	44_V	0.794	0.89
219_V	288_F	0.794	0.89
617_C	620_P	0.793	0.89
364_A	371_A	0.789	0.89
205_G	210_A	0.788	0.89
372_G	375_D	0.786	0.88
70_L	73_A	0.784	0.88
71_R	75_R	0.784	0.88
29_V	48_V	0.783	0.88
493_H	497_L	0.782	0.88
29_V	32_L	0.781	0.88
25_P	303_H	0.779	0.88
263_A	307_L	0.778	0.88
497_L	594_P	0.778	0.88
222_S	244_D	0.777	0.88
623_C	626_G	0.777	0.88
97_R	100_A	0.776	0.88
53_T	160_R	0.776	0.88
33_V	180_Y	0.775	0.88
361_D	364_A	0.775	0.88
361_D	371_A	0.774	0.88
374_S	378_G	0.772	0.88
15_R	106_S	0.771	0.87
637_E	640_A	0.770	0.87
217_R	221_Q	0.770	0.87
420_G	425_T	0.770	0.87
65_M	72_M	0.770	0.87
363_G	367_G	0.769	0.87
33_V	46_V	0.769	0.87
468_H	491_R	0.766	0.87
474_A	611_L	0.765	0.87
20_E	303_H	0.763	0.87
127_T	134_G	0.763	0.87
179_R	263_A	0.762	0.87
521_A	525_E	0.762	0.87
487_A	592_C	0.762	0.87
527_A	570_F	0.761	0.87
365_A	375_D	0.761	0.87
426_G	429_D	0.761	0.87
21_V	77_H	0.760	0.87
348_D	360_R	0.759	0.87
363_G	369_D	0.758	0.87
541_A	546_R	0.758	0.87
225_T	240_G	0.756	0.86
60_D	64_G	0.754	0.86
17_A	303_H	0.754	0.86
411_D	424_R	0.753	0.86
208_Q	225_T	0.753	0.86
497_L	587_L	0.751	0.86
236_E	295_C	0.750	0.86
602_L	607_V	0.748	0.86
5_I	114_T	0.747	0.86
352_S	356_S	0.747	0.86
612_D	615_D	0.746	0.86
515_E	543_R	0.745	0.86
352_S	359_D	0.745	0.86
61_D	143_A	0.742	0.85
222_S	246_E	0.741	0.85
445_E	448_D	0.739	0.85
580_A	584_D	0.737	0.85
466_Q	472_V	0.737	0.85
513_E	542_G	0.736	0.85
413_T	420_G	0.734	0.85
411_D	418_G	0.734	0.85
243_S	277_Y	0.734	0.85
320_A	324_G	0.734	0.85
238_V	293_V	0.733	0.85
358_T	364_A	0.733	0.85
368_G	381_T	0.730	0.84
350_E	357_P	0.730	0.84
252_R	286_Y	0.730	0.84
225_T	239_H	0.728	0.84
428_F	431_P	0.727	0.84
531_L	563_A	0.724	0.84
425_T	430_A	0.724	0.84
249_R	254_Y	0.723	0.84
597_K	627_R	0.722	0.84
370_A	376_G	0.722	0.84
372_G	377_N	0.721	0.84
17_A	77_H	0.720	0.84
351_I	358_T	0.719	0.84
23_E	310_R	0.719	0.84
357_P	364_A	0.719	0.84
230_P	235_V	0.718	0.83
364_A	368_G	0.717	0.83
34_E	301_N	0.715	0.83
68_D	71_R	0.715	0.83
481_V	491_R	0.714	0.83
414_R	420_G	0.714	0.83
424_R	427_R	0.713	0.83
77_H	106_S	0.711	0.83
417_P	424_R	0.710	0.83
423_S	428_F	0.709	0.83
597_K	623_C	0.707	0.83
301_N	304_P	0.707	0.83
472_V	484_D	0.707	0.83
413_T	419_S	0.706	0.82
482_L	599_N	0.702	0.82
424_R	429_D	0.701	0.82
192_T	197_E	0.701	0.82
419_S	424_R	0.700	0.82
421_T	426_G	0.699	0.82
367_G	370_A	0.698	0.82
484_D	592_C	0.698	0.82
466_Q	484_D	0.697	0.82
353_P	359_D	0.696	0.82
412_G	419_S	0.696	0.82
124_A	136_V	0.695	0.81
366_G	453_S	0.695	0.81
371_A	375_D	0.695	0.81
470_T	485_Q	0.695	0.81
14_A	102_Y	0.695	0.81
39_A	58_V	0.695	0.81
182_L	290_V	0.694	0.81
25_P	51_G	0.694	0.81
97_R	299_D	0.692	0.81
373_Q	376_G	0.691	0.81
355_H	362_A	0.691	0.81
377_N	381_T	0.691	0.81
482_L	638_L	0.689	0.81
415_E	422_E	0.688	0.81
416_R	421_T	0.687	0.81
238_V	520_E	0.686	0.81
410_T	417_P	0.686	0.81
378_G	384_S	0.684	0.80
416_R	425_T	0.684	0.80
299_D	304_P	0.683	0.80
375_D	382_A	0.681	0.80
413_T	423_S	0.680	0.80
598_G	625_H	0.679	0.80
347_G	350_E	0.678	0.80
370_A	375_D	0.676	0.80
354_E	357_P	0.676	0.80
419_S	422_E	0.675	0.80
30_K	301_N	0.675	0.80
17_A	25_P	0.675	0.80
418_G	422_E	0.675	0.80
28_V	108_A	0.674	0.79
28_V	104_I	0.674	0.79
482_L	633_V	0.673	0.79
440_G	446_A	0.672	0.79
133_A	136_V	0.672	0.79
249_R	253_E	0.672	0.79
321_V	328_A	0.672	0.79
487_A	623_C	0.670	0.79
364_A	373_Q	0.668	0.79
620_P	630_I	0.668	0.79
353_P	360_R	0.666	0.79
597_K	631_V	0.665	0.79
20_E	24_R	0.664	0.78
365_A	372_G	0.662	0.78
362_A	369_D	0.662	0.78
360_R	370_A	0.662	0.78
365_A	371_A	0.661	0.78
94_L	183_A	0.661	0.78
368_G	374_S	0.661	0.78
590_L	594_P	0.661	0.78
490_E	495_E	0.661	0.78
356_S	361_D	0.660	0.78
528_L	538_A	0.660	0.78
26_A	176_A	0.660	0.78
240_G	243_S	0.658	0.78
318_K	322_E	0.658	0.78
435_A	440_G	0.658	0.78
410_T	422_E	0.658	0.78
301_N	306_K	0.657	0.78
99_E	260_N	0.657	0.78
412_G	417_P	0.657	0.78
242_V	325_V	0.657	0.78
586_V	589_D	0.656	0.78
444_P	452_T	0.656	0.78
410_T	415_E	0.655	0.77
522_A	525_E	0.655	0.77
420_G	426_G	0.654	0.77
458_L	615_D	0.652	0.77
415_E	421_T	0.652	0.77
225_T	241_Y	0.651	0.77
319_A	323_A	0.650	0.77
102_Y	196_R	0.650	0.77
421_T	427_R	0.650	0.77
367_G	374_S	0.648	0.77
461_L	615_D	0.645	0.76
281_L	329_L	0.645	0.76
524_F	563_A	0.645	0.76
372_G	380_R	0.644	0.76
97_R	304_P	0.643	0.76
528_L	545_A	0.641	0.76
379_Q	384_S	0.640	0.76
592_C	598_G	0.639	0.76
486_H	596_I	0.639	0.76
490_E	497_L	0.638	0.76
624_P	627_R	0.638	0.76
513_E	541_A	0.638	0.76
417_P	420_G	0.638	0.76
521_A	543_R	0.638	0.76
431_P	435_A	0.637	0.76
115_R	118_N	0.637	0.76
374_S	384_S	0.637	0.76
357_P	360_R	0.634	0.75
372_G	449_Q	0.633	0.75
7_A	13_V	0.632	0.75
185_P	241_Y	0.631	0.75
371_A	374_S	0.631	0.75
255_L	274_L	0.630	0.75
181_A	214_V	0.630	0.75
420_G	427_R	0.629	0.75
384_S	451_T	0.629	0.75
358_T	363_G	0.628	0.74
484_D	627_R	0.628	0.74
416_R	419_S	0.627	0.74
484_D	495_E	0.624	0.74
415_E	426_G	0.623	0.74
48_V	191_L	0.622	0.74
377_N	384_S	0.621	0.74
352_S	357_P	0.620	0.74
201_T	214_V	0.620	0.74
257_T	289_A	0.619	0.73
598_G	623_C	0.619	0.73
364_A	372_G	0.618	0.73
498_Q	618_E	0.618	0.73
224_R	244_D	0.618	0.73
607_V	622_A	0.618	0.73
596_I	625_H	0.618	0.73
94_L	184_N	0.618	0.73
417_P	425_T	0.617	0.73
19_G	304_P	0.617	0.73
446_A	451_T	0.616	0.73
411_D	427_R	0.615	0.73
271_E	275_D	0.615	0.73
585_A	589_D	0.614	0.73
167_A	171_G	0.613	0.73
598_G	627_R	0.613	0.73
277_Y	329_L	0.613	0.73
615_D	618_E	0.612	0.73
276_G	325_V	0.611	0.72
594_P	597_K	0.610	0.72
57_V	148_E	0.610	0.72
492_V	617_C	0.609	0.72
558_L	562_L	0.608	0.72
418_G	429_D	0.608	0.72
539_E	542_G	0.608	0.72
358_T	378_G	0.607	0.72
357_P	363_G	0.607	0.72
35_N	38_D	0.607	0.72
427_R	430_A	0.606	0.72
70_L	128_V	0.606	0.72
362_A	373_Q	0.605	0.72
447_D	450_D	0.605	0.72
12_T	91_V	0.603	0.71
363_G	380_R	0.603	0.71
282_A	639_A	0.602	0.71
259_V	264_V	0.602	0.71
71_R	126_I	0.601	0.71
448_D	452_T	0.601	0.71
485_Q	489_D	0.601	0.71
16_I	19_G	0.598	0.71
41_A	44_V	0.598	0.71
172_H	271_E	0.598	0.71
486_H	597_K	0.597	0.71
416_R	423_S	0.596	0.71
96_F	304_P	0.596	0.71
415_E	425_T	0.596	0.71
346_P	387_T	0.596	0.71
379_Q	386_A	0.596	0.71
593_S	598_G	0.596	0.71
9_D	282_A	0.595	0.70
485_Q	620_P	0.594	0.70
617_C	629_T	0.594	0.70
348_D	352_S	0.594	0.70
420_G	424_R	0.593	0.70
426_G	430_A	0.591	0.70
18_A	303_H	0.591	0.70
203_G	215_Y	0.590	0.70
441_A	444_P	0.590	0.70
465_G	470_T	0.589	0.70
497_L	501_V	0.589	0.70
96_F	301_N	0.589	0.70
210_A	266_D	0.588	0.70
34_E	52_G	0.586	0.69
4_R	68_D	0.586	0.69
591_A	594_P	0.586	0.69
210_A	215_Y	0.585	0.69
476_A	632_E	0.585	0.69
317_V	321_V	0.584	0.69
211_A	223_L	0.584	0.69
419_S	426_G	0.584	0.69
177_V	199_F	0.583	0.69
358_T	362_A	0.583	0.69
411_D	417_P	0.583	0.69
376_G	387_T	0.583	0.69
65_M	93_T	0.583	0.69
491_R	494_Y	0.582	0.69
620_P	624_P	0.581	0.69
512_A	560_A	0.581	0.69
356_S	360_R	0.580	0.69
368_G	375_D	0.580	0.69
356_S	365_A	0.580	0.69
162_Y	311_F	0.580	0.69
364_A	376_G	0.579	0.68
19_G	25_P	0.579	0.68
355_H	359_D	0.579	0.68
417_P	427_R	0.578	0.68
448_D	451_T	0.577	0.68
377_N	383_A	0.576	0.68
69_D	73_A	0.576	0.68
537_D	548_T	0.575	0.68
411_D	419_S	0.575	0.68
22_V	158_A	0.575	0.68
436_R	452_T	0.574	0.68
598_G	622_A	0.573	0.68
474_A	481_V	0.572	0.67
487_A	493_H	0.572	0.67
380_R	385_G	0.570	0.67
353_P	386_A	0.570	0.67
539_E	546_R	0.569	0.67
463_V	611_L	0.569	0.67
596_I	627_R	0.568	0.67
481_V	632_E	0.568	0.67
100_A	299_D	0.568	0.67
481_V	487_A	0.566	0.67
364_A	379_Q	0.565	0.67
36_S	58_V	0.565	0.67
369_D	387_T	0.563	0.66
354_E	386_A	0.563	0.66
361_D	369_D	0.562	0.66
185_P	210_A	0.562	0.66
272_A	276_G	0.561	0.66
411_D	430_A	0.561	0.66
616_A	633_V	0.561	0.66
377_N	437_L	0.561	0.66
115_R	119_A	0.561	0.66
547_V	636_D	0.561	0.66
33_V	176_A	0.560	0.66
366_G	374_S	0.560	0.66
488_A	614_L	0.559	0.66
436_R	440_G	0.559	0.66
82_L	96_F	0.558	0.66
367_G	375_D	0.558	0.66
359_D	364_A	0.558	0.66
14_A	179_R	0.557	0.65
324_G	328_A	0.557	0.65
359_D	363_G	0.556	0.65
360_R	363_G	0.555	0.65
372_G	378_G	0.555	0.65
424_R	434_N	0.553	0.65
314_E	318_K	0.553	0.65
366_G	451_T	0.553	0.65
415_E	423_S	0.553	0.65
351_I	357_P	0.553	0.65
360_R	366_G	0.552	0.65
377_N	382_A	0.552	0.65
14_A	180_Y	0.552	0.65
348_D	353_P	0.552	0.65
463_V	608_V	0.551	0.65
255_L	472_V	0.551	0.65
355_H	364_A	0.549	0.64
101_L	110_L	0.549	0.64
614_L	630_I	0.548	0.64
119_A	124_A	0.548	0.64
516_L	545_A	0.547	0.64
383_A	417_P	0.547	0.64
412_G	420_G	0.546	0.64
351_I	356_S	0.546	0.64
359_D	369_D	0.545	0.64
16_I	106_S	0.545	0.64
22_V	107_V	0.545	0.64
100_A	306_K	0.545	0.64
376_G	380_R	0.543	0.64
607_V	621_Y	0.543	0.64
487_A	629_T	0.543	0.64
223_L	243_S	0.543	0.64
350_E	363_G	0.543	0.64
420_G	429_D	0.542	0.63
472_V	491_R	0.542	0.63
471_Y	484_D	0.542	0.63
303_H	308_E	0.542	0.63
466_Q	490_E	0.541	0.63
422_E	428_F	0.541	0.63
550_V	559_D	0.541	0.63
438_P	452_T	0.540	0.63
498_Q	584_D	0.539	0.63
19_G	303_H	0.539	0.63
18_A	78_T	0.539	0.63
212_L	220_A	0.538	0.63
359_D	370_A	0.537	0.63
361_D	365_A	0.536	0.63
348_D	365_A	0.536	0.63
363_G	371_A	0.536	0.63
364_A	384_S	0.535	0.62
65_M	282_A	0.535	0.62
57_V	174_N	0.535	0.62
351_I	360_R	0.535	0.62
349_A	364_A	0.533	0.62
65_M	74_V	0.533	0.62
418_G	428_F	0.532	0.62
440_G	444_P	0.532	0.62
311_F	318_K	0.532	0.62
497_L	591_A	0.530	0.62
494_Y	624_P	0.530	0.62
373_Q	378_G	0.530	0.62
423_S	429_D	0.529	0.62
361_D	366_G	0.529	0.62
108_A	296_E	0.529	0.62
521_A	544_T	0.528	0.61
348_D	366_G	0.528	0.61
20_E	23_E	0.527	0.61
349_A	355_H	0.527	0.61
364_A	369_D	0.527	0.61
413_T	417_P	0.527	0.61
346_P	350_E	0.527	0.61
369_D	374_S	0.526	0.61
262_R	306_K	0.525	0.61
468_H	475_E	0.525	0.61
495_E	498_Q	0.525	0.61
443_G	447_D	0.525	0.61
350_E	361_D	0.525	0.61
13_V	90_G	0.525	0.61
415_E	424_R	0.525	0.61
620_P	629_T	0.524	0.61
105_G	128_V	0.524	0.61
445_E	451_T	0.524	0.61
346_P	370_A	0.524	0.61
354_E	369_D	0.523	0.61
173_V	191_L	0.523	0.61
418_G	423_S	0.522	0.61
347_G	351_I	0.521	0.60
82_L	122_T	0.521	0.60
370_A	380_R	0.520	0.60
421_T	428_F	0.519	0.60
582_A	587_L	0.518	0.60
347_G	352_S	0.517	0.60
359_D	371_A	0.517	0.60
494_Y	588_A	0.516	0.60
376_G	446_A	0.515	0.59
349_A	354_E	0.515	0.59
487_A	625_H	0.515	0.59
91_V	483_V	0.515	0.59
30_K	300_A	0.515	0.59
439_T	452_T	0.515	0.59
442_G	448_D	0.515	0.59
550_V	555_A	0.514	0.59
356_S	369_D	0.514	0.59
443_G	446_A	0.514	0.59
235_V	316_G	0.513	0.59
447_D	452_T	0.513	0.59
487_A	491_R	0.512	0.59
611_L	615_D	0.512	0.59
358_T	365_A	0.512	0.59
58_V	585_A	0.511	0.59
350_E	426_G	0.511	0.59
378_G	381_T	0.511	0.59
441_A	447_D	0.511	0.59
22_V	612_D	0.511	0.59
615_D	620_P	0.511	0.59
423_S	426_G	0.510	0.59
350_E	354_E	0.510	0.59
97_R	306_K	0.510	0.59
376_G	384_S	0.510	0.59
211_A	214_V	0.509	0.59
383_A	386_A	0.509	0.59
215_Y	254_Y	0.509	0.59
370_A	444_P	0.508	0.58
381_T	420_G	0.507	0.58
416_R	428_F	0.507	0.58
442_G	450_D	0.505	0.58
59_A	141_H	0.505	0.58
217_R	514_L	0.503	0.58
29_V	46_V	0.503	0.58
425_T	431_P	0.503	0.58
76_Q	99_E	0.502	0.58
428_F	444_P	0.502	0.58
355_H	361_D	0.502	0.58
598_G	639_A	0.502	0.58
119_A	122_T	0.501	0.57
52_G	301_N	0.501	0.57
355_H	380_R	0.501	0.57
36_S	148_E	0.500	0.57

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3h4lA	2	0.4977	100	0.561	Contact Map
1b63A	2	0.4917	100	0.566	Contact Map
1h7sA	1	0.4476	100	0.567	Contact Map
4p7aA	2	0.4476	100	0.573	Contact Map
3ncvA	2	0.2792	100	0.711	Contact Map
3kdgA	2	0.2853	100	0.715	Contact Map
4e4wB	1	0.3111	100	0.728	Contact Map
3cwvA	1	0.4643	100	0.737	Contact Map
1kijA	2	0.5068	100	0.763	Contact Map
4ipeA	2	0.7906	100	0.763	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0158 seconds.