Q9HSA5 - HALSA - GREMLIN Contacts

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Q9HSA5 - Pyruvate kinase

UniProt:	Q9HSA5	Sequences: MRNAKIVCTLGPATNDDASVRALADAGMTVARINASHGDAAARRELIETTRAVDAQTDKPLAVMLDTQGPEVRTAPIDDDGTIHIETGSDVAFVEGDTATPDRIGISTSIAAAEPGDTVLLDDGRIEADVDRVAGDTVHATVVSGGSLGSRKGVNVPGVELDVDVVTEKDRRDLALAAELDVDYVAASFVRDADDVLAVNRVLESHGADIPIVAKIERAGAVENLDGIIDAAQGVMVARGDLGVECPMEDVPMIQKRIIAQCRDAGVPVITATEMLDSMVHARRPTRAEASDVANAVLDGTDGVMLSAETAVGDNPTRVVETMDRIVREVEGSAEYSERQEQAVPTADGTAKTDALARSARYLARDIDASAVVVASESGYTARKAAKFRPSVPVVCATPSHDVRRQLALNWGVHANYAAVAEGDATTVVERAVQAAVDSGVVASGDTVVVLVGMMTELEGASTTNTLKVHVAAETLSTGRAVVDGRTTGRTYRADSGDLSDAPENAVVLLAHGFDGEFDGDLSKIGAIVSADAGLTGYPAVIARELDVPMVGDVDVDAVPAGDLVTVDGERGVVYEADQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	579 (465)
Sequences:	4038 (2243)
Seq/√Len:	104.0

ECOLI - KPYK2 KPYK1
BACSU - KPYK
HALSA - Q9HSA5
SULSO - Q97ZD7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
21_R	56_Q	4.366	1.00
131_D	141_T	4.338	1.00
214_A	232_A	4.301	1.00
226_D	261_Q	4.050	1.00
17_D	52_A	3.466	1.00
225_L	258_I	3.374	1.00
44_R	48_E	3.355	1.00
78_D	100_T	3.155	1.00
129_D	141_T	3.146	1.00
197_L	231_A	3.086	1.00
8_C	28_M	3.071	1.00
65_L	177_A	2.983	1.00
200_N	212_I	2.923	1.00
271_T	301_T	2.856	1.00
222_V	254_I	2.832	1.00
196_V	214_A	2.811	1.00
250_D	329_E	2.776	1.00
62_A	408_A	2.776	1.00
28_M	31_A	2.764	1.00
129_D	143_V	2.618	1.00
16_D	19_S	2.595	1.00
132_R	139_H	2.529	1.00
44_R	180_L	2.528	1.00
19_S	22_A	2.514	1.00
90_D	139_H	2.483	1.00
76_P	151_R	2.437	1.00
86_E	89_S	2.414	1.00
90_D	131_D	2.388	1.00
196_V	212_I	2.304	1.00
91_V	104_I	2.303	1.00
249_E	325_R	2.272	1.00
42_A	46_L	2.226	1.00
24_A	61_L	2.202	1.00
230_D	265_A	2.199	1.00
174_L	185_V	2.178	1.00
15_N	46_L	2.172	1.00
281_H	314_D	2.136	1.00
370_S	446_D	2.127	1.00
47_I	180_L	2.095	1.00
398_T	404_R	2.093	1.00
25_D	57_T	2.085	1.00
213_V	234_G	2.055	1.00
194_D	198_A	2.051	1.00
246_C	254_I	2.050	1.00
17_D	49_T	2.006	1.00
304_V	327_V	1.999	1.00
324_D	328_R	1.989	1.00
78_D	98_T	1.963	1.00
181_D	402_D	1.963	1.00
201_R	205_S	1.953	1.00
89_S	101_P	1.936	1.00
121_L	148_L	1.929	1.00
90_D	141_T	1.891	1.00
103_R	137_T	1.877	1.00
256_K	299_D	1.867	1.00
178_A	210_I	1.857	1.00
96_G	136_D	1.821	1.00
211_P	406_Q	1.813	1.00
115_P	133_V	1.810	1.00
82_T	147_S	1.809	1.00
51_R	54_D	1.804	1.00
19_S	317_T	1.791	1.00
193_A	227_G	1.759	1.00
259_I	271_T	1.744	1.00
93_F	128_A	1.734	1.00
91_V	140_A	1.730	1.00
373_V	448_V	1.728	1.00
10_L	20_V	1.722	1.00
33_I	47_I	1.719	1.00
47_I	63_V	1.719	1.00
194_D	197_L	1.719	1.00
175_A	206_H	1.715	1.00
85_I	142_V	1.713	1.00
84_H	147_S	1.705	1.00
112_A	162_D	1.703	1.00
21_R	25_D	1.703	1.00
363_L	467_L	1.700	1.00
118_T	127_E	1.698	1.00
225_L	229_I	1.694	1.00
168_E	172_R	1.693	1.00
7_V	270_I	1.684	1.00
171_R	175_A	1.684	1.00
29_T	59_K	1.683	1.00
434_Q	438_D	1.678	1.00
128_A	140_A	1.666	1.00
235_V	258_I	1.652	1.00
404_R	417_Y	1.638	1.00
169_K	173_D	1.633	1.00
17_D	56_Q	1.618	1.00
83_I	101_P	1.616	1.00
52_A	56_Q	1.597	1.00
96_G	103_R	1.597	1.00
41_A	44_R	1.596	1.00
30_V	64_M	1.584	1.00
219_A	223_E	1.580	1.00
22_A	25_D	1.574	1.00
89_S	142_V	1.573	1.00
67_T	71_E	1.573	1.00
257_R	261_Q	1.566	1.00
92_A	139_H	1.564	1.00
160_E	220_G	1.558	1.00
24_A	53_V	1.558	1.00
92_A	137_T	1.557	1.00
7_V	30_V	1.544	1.00
118_T	129_D	1.530	1.00
171_R	198_A	1.527	1.00
187_A	199_V	1.523	1.00
318_R	321_E	1.518	1.00
77_I	150_S	1.515	1.00
114_E	117_D	1.488	1.00
134_A	137_T	1.487	1.00
213_V	270_I	1.487	1.00
17_D	53_V	1.478	1.00
435_A	438_D	1.475	1.00
81_G	150_S	1.469	1.00
2_R	324_D	1.466	1.00
31_A	50_T	1.466	1.00
65_L	182_V	1.454	1.00
45_E	48_E	1.442	1.00
21_R	57_T	1.435	1.00
95_E	110_I	1.435	1.00
96_G	137_T	1.421	1.00
407_L	410_N	1.421	1.00
33_I	50_T	1.417	1.00
315_N	318_R	1.405	1.00
172_R	175_A	1.398	1.00
248_M	322_T	1.393	1.00
369_A	449_V	1.393	1.00
110_I	138_V	1.382	1.00
40_A	176_L	1.379	1.00
63_V	182_V	1.373	1.00
94_V	103_R	1.350	0.99
280_V	308_A	1.346	0.99
376_S	396_C	1.345	0.99
45_E	49_T	1.341	0.99
97_D	109_S	1.333	0.99
134_A	139_H	1.332	0.99
122_D	125_R	1.315	0.99
38_G	43_R	1.308	0.99
74_T	126_I	1.304	0.99
435_A	439_S	1.303	0.99
53_V	57_T	1.303	0.99
19_S	23_L	1.293	0.99
171_R	202_V	1.291	0.99
44_R	179_E	1.290	0.99
26_A	321_E	1.282	0.99
39_D	42_A	1.281	0.99
193_A	231_A	1.268	0.99
117_D	159_V	1.265	0.99
277_D	281_H	1.258	0.99
437_V	444_S	1.258	0.99
321_E	325_R	1.255	0.99
74_T	104_I	1.255	0.99
224_N	227_G	1.254	0.99
209_D	402_D	1.253	0.99
133_V	138_V	1.252	0.99
251_V	291_S	1.250	0.99
8_C	31_A	1.239	0.99
75_A	105_G	1.235	0.99
16_D	49_T	1.230	0.99
261_Q	265_A	1.225	0.99
297_V	327_V	1.223	0.99
121_L	128_A	1.213	0.99
48_E	52_A	1.213	0.99
218_R	221_A	1.205	0.99
23_L	320_V	1.202	0.99
18_A	21_R	1.197	0.99
175_A	179_E	1.196	0.99
113_A	138_V	1.195	0.99
94_V	137_T	1.191	0.99
14_T	19_S	1.187	0.99
355_A	363_L	1.184	0.99
329_E	332_G	1.183	0.99
4_A	327_V	1.180	0.99
254_I	258_I	1.180	0.99
21_R	53_V	1.174	0.99
10_L	46_L	1.173	0.98
178_A	203_L	1.172	0.98
87_T	145_G	1.172	0.98
33_I	182_V	1.164	0.98
229_I	261_Q	1.160	0.98
43_R	46_L	1.143	0.98
178_A	206_H	1.141	0.98
396_C	407_L	1.141	0.98
293_V	326_I	1.140	0.98
352_K	447_T	1.136	0.98
10_L	14_T	1.134	0.98
177_A	182_V	1.134	0.98
15_N	45_E	1.133	0.98
22_A	321_E	1.133	0.98
49_T	52_A	1.131	0.98
83_I	148_L	1.127	0.98
156_V	159_V	1.117	0.98
275_M	293_V	1.115	0.98
24_A	59_K	1.114	0.98
40_A	173_D	1.105	0.98
259_I	301_T	1.102	0.98
371_A	395_V	1.101	0.98
47_I	176_L	1.096	0.98
15_N	49_T	1.088	0.98
424_D	427_T	1.085	0.97
175_A	205_S	1.085	0.97
17_D	21_R	1.085	0.97
82_T	149_G	1.069	0.97
14_T	23_L	1.069	0.97
55_A	401_H	1.067	0.97
197_L	201_R	1.061	0.97
203_L	208_A	1.061	0.97
363_L	469_V	1.059	0.97
86_E	145_G	1.053	0.97
131_D	139_H	1.051	0.97
277_D	280_V	1.046	0.97
193_A	197_L	1.045	0.97
452_V	466_T	1.044	0.97
33_I	63_V	1.043	0.97
396_C	413_V	1.041	0.97
253_M	298_L	1.033	0.97
86_E	101_P	1.033	0.97
127_E	143_V	1.031	0.97
7_V	303_G	1.029	0.97
68_Q	71_E	1.029	0.97
35_A	65_L	1.026	0.96
76_P	150_S	1.022	0.96
374_V	385_A	1.020	0.96
354_D	387_K	1.016	0.96
142_V	145_G	1.013	0.96
110_I	133_V	1.012	0.96
277_D	308_A	1.007	0.96
193_A	224_N	1.005	0.96
179_E	206_H	1.004	0.96
30_V	303_G	0.999	0.96
10_L	50_T	0.995	0.96
447_T	471_V	0.993	0.96
93_F	106_I	0.991	0.96
370_S	443_A	0.989	0.96
383_R	410_N	0.989	0.96
22_A	317_T	0.986	0.96
128_A	142_V	0.984	0.96
156_V	161_L	0.983	0.96
71_E	218_R	0.983	0.96
226_D	229_I	0.978	0.95
50_T	63_V	0.977	0.95
49_T	53_V	0.973	0.95
47_I	182_V	0.971	0.95
283_R	315_N	0.970	0.95
74_T	149_G	0.969	0.95
100_T	103_R	0.967	0.95
290_A	326_I	0.966	0.95
48_E	180_L	0.962	0.95
42_A	45_E	0.962	0.95
99_A	104_I	0.960	0.95
225_L	261_Q	0.958	0.95
397_A	418_A	0.950	0.95
200_N	233_Q	0.949	0.95
171_R	201_R	0.942	0.94
121_L	140_A	0.939	0.94
118_T	143_V	0.939	0.94
198_A	201_R	0.937	0.94
87_T	314_D	0.933	0.94
166_V	171_R	0.932	0.94
108_T	112_A	0.932	0.94
395_V	436_A	0.931	0.94
68_Q	169_K	0.929	0.94
106_I	154_V	0.929	0.94
203_L	210_I	0.925	0.94
452_V	455_M	0.922	0.94
168_E	171_R	0.922	0.94
122_D	149_G	0.921	0.94
442_V	472_A	0.919	0.94
182_V	210_I	0.914	0.93
104_I	148_L	0.913	0.93
358_R	362_Y	0.909	0.93
122_D	277_D	0.907	0.93
232_A	235_V	0.907	0.93
44_R	176_L	0.905	0.93
386_A	410_N	0.905	0.93
26_A	317_T	0.904	0.93
183_D	405_R	0.903	0.93
90_D	132_R	0.902	0.93
80_D	150_S	0.901	0.93
222_V	242_L	0.901	0.93
260_A	264_D	0.898	0.93
20_V	53_V	0.896	0.93
84_H	145_G	0.895	0.93
77_I	91_V	0.893	0.93
248_M	290_A	0.893	0.93
204_E	208_A	0.892	0.93
155_N	245_E	0.891	0.93
26_A	320_V	0.891	0.93
293_V	304_V	0.891	0.93
53_V	56_Q	0.889	0.92
191_R	220_G	0.887	0.92
174_L	199_V	0.881	0.92
276_L	319_V	0.880	0.92
127_E	284_R	0.879	0.92
229_I	262_C	0.879	0.92
88_G	141_T	0.876	0.92
455_M	465_N	0.874	0.92
93_F	140_A	0.874	0.92
229_I	265_A	0.871	0.92
4_A	297_V	0.867	0.91
14_T	310_T	0.866	0.91
192_D	195_D	0.864	0.91
68_Q	173_D	0.862	0.91
77_I	148_L	0.860	0.91
64_M	186_A	0.855	0.91
357_A	385_A	0.855	0.91
227_G	230_D	0.853	0.91
36_S	173_D	0.850	0.91
219_A	250_D	0.850	0.91
196_V	232_A	0.848	0.91
77_I	81_G	0.846	0.90
174_L	202_V	0.844	0.90
126_I	148_L	0.842	0.90
40_A	44_R	0.835	0.90
229_I	258_I	0.832	0.90
176_L	180_L	0.831	0.90
226_D	265_A	0.829	0.90
315_N	319_V	0.828	0.90
60_P	404_R	0.826	0.89
113_A	119_V	0.826	0.89
57_T	60_P	0.826	0.89
54_D	61_L	0.823	0.89
93_F	104_I	0.823	0.89
60_P	415_A	0.823	0.89
24_A	57_T	0.822	0.89
178_A	185_V	0.821	0.89
253_M	330_V	0.819	0.89
398_T	417_Y	0.818	0.89
131_D	140_A	0.817	0.89
356_L	451_L	0.815	0.89
433_V	448_V	0.814	0.89
115_P	132_R	0.813	0.89
259_I	269_V	0.812	0.89
62_A	184_Y	0.812	0.89
41_A	45_E	0.811	0.89
115_P	131_D	0.807	0.88
429_V	450_V	0.805	0.88
16_D	23_L	0.804	0.88
184_Y	213_V	0.800	0.88
175_A	202_V	0.800	0.88
317_T	321_E	0.798	0.88
161_L	164_D	0.795	0.88
20_V	49_T	0.793	0.87
65_L	71_E	0.793	0.87
71_E	221_A	0.790	0.87
117_D	130_V	0.789	0.87
67_T	218_R	0.787	0.87
403_V	407_L	0.787	0.87
71_E	153_G	0.787	0.87
123_D	153_G	0.785	0.87
213_V	409_L	0.784	0.87
90_D	102_D	0.782	0.87
374_V	381_T	0.782	0.87
175_A	178_A	0.782	0.87
123_D	274_E	0.781	0.87
225_L	257_R	0.778	0.86
358_R	366_D	0.778	0.86
20_V	50_T	0.775	0.86
200_N	204_E	0.773	0.86
298_L	333_S	0.768	0.86
10_L	33_I	0.765	0.85
360_A	449_V	0.764	0.85
50_T	54_D	0.760	0.85
383_R	406_Q	0.759	0.85
77_I	149_G	0.758	0.85
177_A	185_V	0.756	0.85
199_V	212_I	0.756	0.85
78_D	101_P	0.756	0.85
402_D	406_Q	0.755	0.85
77_I	104_I	0.755	0.85
83_I	104_I	0.755	0.85
87_T	141_T	0.755	0.85
453_G	460_G	0.753	0.85
92_A	103_R	0.753	0.85
376_S	382_A	0.750	0.84
30_V	62_A	0.745	0.84
371_A	442_V	0.744	0.84
93_F	119_V	0.744	0.84
354_D	384_K	0.743	0.84
7_V	28_M	0.742	0.84
433_V	470_H	0.741	0.84
401_H	417_Y	0.740	0.84
362_Y	366_D	0.740	0.84
116_G	129_D	0.740	0.84
360_A	364_A	0.739	0.83
382_A	396_C	0.737	0.83
397_A	436_A	0.737	0.83
52_A	55_A	0.734	0.83
380_Y	384_K	0.733	0.83
158_G	219_A	0.733	0.83
364_A	372_V	0.730	0.83
91_V	100_T	0.729	0.83
122_D	153_G	0.725	0.82
369_A	469_V	0.722	0.82
40_A	172_R	0.721	0.82
230_D	267_V	0.721	0.82
429_V	468_K	0.720	0.82
263_R	302_D	0.719	0.82
24_A	54_D	0.716	0.81
14_T	317_T	0.714	0.81
114_E	133_V	0.709	0.81
39_D	151_R	0.705	0.80
225_L	262_C	0.704	0.80
126_I	142_V	0.703	0.80
377_E	400_S	0.702	0.80
367_I	447_T	0.702	0.80
329_E	333_S	0.702	0.80
234_G	268_P	0.700	0.80
126_I	145_G	0.699	0.80
298_L	330_V	0.698	0.80
35_A	173_D	0.696	0.80
54_D	57_T	0.695	0.80
21_R	52_A	0.695	0.80
24_A	50_T	0.694	0.79
436_A	442_V	0.694	0.79
76_P	98_T	0.694	0.79
225_L	235_V	0.693	0.79
19_S	49_T	0.692	0.79
184_Y	410_N	0.692	0.79
356_L	467_L	0.692	0.79
74_T	77_I	0.690	0.79
353_T	380_Y	0.689	0.79
74_T	154_V	0.689	0.79
360_A	451_L	0.689	0.79
10_L	31_A	0.688	0.79
67_T	187_A	0.688	0.79
68_Q	308_A	0.687	0.79
62_A	405_R	0.686	0.79
226_D	257_R	0.684	0.78
178_A	208_A	0.683	0.78
91_V	99_A	0.683	0.78
157_P	245_E	0.682	0.78
373_V	442_V	0.679	0.78
122_D	308_A	0.679	0.78
295_N	299_D	0.678	0.78
216_I	222_V	0.678	0.78
149_G	312_V	0.677	0.78
275_M	304_V	0.676	0.78
35_A	43_R	0.675	0.78
247_P	251_V	0.672	0.77
408_A	415_A	0.670	0.77
77_I	99_A	0.670	0.77
253_M	333_S	0.670	0.77
236_M	307_S	0.670	0.77
275_M	323_M	0.667	0.77
400_S	403_V	0.667	0.77
33_I	43_R	0.665	0.76
433_V	472_A	0.664	0.76
85_I	126_I	0.664	0.76
256_K	295_N	0.661	0.76
125_R	282_A	0.659	0.76
22_A	26_A	0.657	0.76
374_V	382_A	0.656	0.76
163_V	167_T	0.655	0.75
15_N	20_V	0.655	0.75
353_T	384_K	0.654	0.75
10_L	49_T	0.654	0.75
404_R	415_A	0.653	0.75
177_A	181_D	0.652	0.75
89_S	102_D	0.651	0.75
2_R	29_T	0.651	0.75
92_A	95_E	0.650	0.75
80_D	83_I	0.649	0.75
401_H	405_R	0.647	0.75
113_A	130_V	0.646	0.74
87_T	315_N	0.646	0.74
94_V	110_I	0.646	0.74
360_A	372_V	0.645	0.74
108_T	191_R	0.644	0.74
297_V	304_V	0.644	0.74
89_S	128_A	0.644	0.74
460_G	464_T	0.643	0.74
251_V	290_A	0.643	0.74
92_A	134_A	0.642	0.74
30_V	408_A	0.642	0.74
351_A	354_D	0.642	0.74
275_M	307_S	0.641	0.74
15_N	42_A	0.641	0.74
437_V	442_V	0.640	0.74
216_I	225_L	0.640	0.74
312_V	319_V	0.639	0.74
192_D	224_N	0.637	0.73
112_A	191_R	0.635	0.73
450_V	470_H	0.635	0.73
243_G	284_R	0.634	0.73
363_L	367_I	0.633	0.73
297_V	330_V	0.632	0.73
381_T	453_G	0.632	0.73
110_I	136_D	0.631	0.73
37_H	241_D	0.629	0.72
38_G	42_A	0.629	0.72
6_I	323_M	0.629	0.72
91_V	142_V	0.627	0.72
377_E	420_V	0.627	0.72
253_M	329_E	0.626	0.72
91_V	105_G	0.626	0.72
310_T	323_M	0.625	0.72
298_L	334_A	0.625	0.72
80_D	101_P	0.625	0.72
263_R	271_T	0.624	0.72
324_D	327_V	0.624	0.72
385_A	451_L	0.623	0.72
165_V	190_V	0.622	0.72
457_E	460_G	0.621	0.71
85_I	89_S	0.621	0.71
421_A	427_T	0.619	0.71
93_F	121_L	0.619	0.71
75_A	107_S	0.618	0.71
166_V	202_V	0.616	0.71
6_I	320_V	0.616	0.71
202_V	205_S	0.616	0.71
361_R	390_P	0.616	0.71
394_V	413_V	0.616	0.71
68_Q	221_A	0.615	0.71
91_V	101_P	0.615	0.71
126_I	146_G	0.613	0.70
2_R	6_I	0.612	0.70
43_R	177_A	0.612	0.70
339_R	342_Q	0.611	0.70
352_K	374_V	0.610	0.70
268_P	409_L	0.608	0.70
54_D	60_P	0.607	0.70
322_T	326_I	0.607	0.70
10_L	15_N	0.607	0.70
433_V	442_V	0.605	0.70
257_R	333_S	0.605	0.70
434_Q	437_V	0.605	0.70
97_D	105_G	0.603	0.69
202_V	206_H	0.603	0.69
25_D	56_Q	0.603	0.69
90_D	129_D	0.603	0.69
68_Q	218_R	0.603	0.69
77_I	126_I	0.603	0.69
364_A	369_A	0.603	0.69
451_L	464_T	0.602	0.69
297_V	354_D	0.601	0.69
184_Y	409_L	0.601	0.69
198_A	202_V	0.601	0.69
310_T	319_V	0.601	0.69
375_A	428_V	0.599	0.69
72_V	154_V	0.597	0.68
47_I	50_T	0.597	0.68
211_P	383_R	0.595	0.68
449_V	469_V	0.594	0.68
190_V	196_V	0.594	0.68
193_A	216_I	0.594	0.68
50_T	61_L	0.593	0.68
377_E	399_P	0.592	0.68
106_I	138_V	0.591	0.68
276_L	322_T	0.588	0.67
221_A	229_I	0.587	0.67
148_L	151_R	0.587	0.67
111_A	162_D	0.586	0.67
23_L	317_T	0.585	0.67
92_A	136_D	0.585	0.67
54_D	59_K	0.583	0.67
16_D	20_V	0.582	0.67
303_G	409_L	0.580	0.66
25_D	59_K	0.579	0.66
185_V	208_A	0.579	0.66
20_V	23_L	0.578	0.66
216_I	234_G	0.577	0.66
181_D	210_I	0.577	0.66
397_A	416_N	0.576	0.66
74_T	93_F	0.576	0.66
449_V	467_L	0.575	0.66
185_V	203_L	0.574	0.65
122_D	191_R	0.574	0.65
31_A	54_D	0.574	0.65
254_I	257_R	0.572	0.65
360_A	369_A	0.572	0.65
389_R	411_W	0.571	0.65
365_R	391_S	0.571	0.65
82_T	150_S	0.570	0.65
72_V	169_K	0.570	0.65
373_V	397_A	0.570	0.65
233_Q	267_V	0.568	0.65
74_T	148_L	0.568	0.65
65_L	176_L	0.567	0.65
261_Q	264_D	0.567	0.65
35_A	182_V	0.567	0.65
34_N	37_H	0.567	0.65
18_A	49_T	0.566	0.64
465_N	468_K	0.566	0.64
6_I	324_D	0.565	0.64
99_A	105_G	0.565	0.64
266_G	387_K	0.565	0.64
121_L	126_I	0.564	0.64
443_A	446_D	0.564	0.64
39_D	76_P	0.564	0.64
201_R	204_E	0.563	0.64
83_I	100_T	0.563	0.64
106_I	156_V	0.563	0.64
351_A	384_K	0.562	0.64
48_E	179_E	0.562	0.64
203_L	211_P	0.562	0.64
24_A	83_I	0.561	0.64
334_A	339_R	0.561	0.64
187_A	190_V	0.561	0.64
184_Y	211_P	0.561	0.64
14_T	312_V	0.560	0.64
266_G	390_P	0.559	0.63
110_I	135_G	0.558	0.63
236_M	305_M	0.556	0.63
91_V	103_R	0.556	0.63
252_P	411_W	0.555	0.63
23_L	28_M	0.555	0.63
165_V	191_R	0.555	0.63
421_A	428_V	0.555	0.63
166_V	174_L	0.554	0.63
111_A	133_V	0.554	0.63
371_A	393_P	0.554	0.63
71_E	163_V	0.552	0.62
189_F	241_D	0.552	0.62
236_M	272_A	0.551	0.62
235_V	265_A	0.549	0.62
403_V	453_G	0.548	0.62
10_L	28_M	0.546	0.62
270_I	305_M	0.545	0.62
194_D	201_R	0.543	0.61
396_C	415_A	0.543	0.61
367_I	449_V	0.543	0.61
83_I	89_S	0.543	0.61
229_I	267_V	0.542	0.61
425_A	452_V	0.542	0.61
204_E	209_D	0.542	0.61
155_N	167_T	0.540	0.61
216_I	258_I	0.540	0.61
111_A	136_D	0.539	0.61
91_V	149_G	0.539	0.61
384_K	429_V	0.539	0.61
253_M	290_A	0.538	0.61
174_L	207_G	0.538	0.61
367_I	469_V	0.537	0.60
117_D	158_G	0.536	0.60
39_D	172_R	0.536	0.60
322_T	325_R	0.535	0.60
153_G	244_V	0.535	0.60
425_A	466_T	0.535	0.60
98_T	103_R	0.535	0.60
120_L	186_A	0.534	0.60
336_Y	340_Q	0.534	0.60
382_A	415_A	0.533	0.60
174_L	208_A	0.532	0.60
47_I	51_R	0.532	0.60
199_V	202_V	0.532	0.60
190_V	214_A	0.532	0.60
77_I	82_T	0.531	0.60
14_T	311_A	0.531	0.60
67_T	153_G	0.530	0.59
386_A	394_V	0.528	0.59
44_R	47_I	0.527	0.59
189_F	245_E	0.526	0.59
89_S	145_G	0.526	0.59
248_M	291_S	0.524	0.59
271_T	300_G	0.524	0.59
395_V	441_V	0.524	0.59
85_I	91_V	0.523	0.58
275_M	301_T	0.523	0.58
95_E	135_G	0.523	0.58
189_F	236_M	0.522	0.58
399_P	417_Y	0.522	0.58
236_M	275_M	0.521	0.58
363_L	449_V	0.520	0.58
263_R	387_K	0.519	0.58
166_V	199_V	0.519	0.58
192_D	227_G	0.518	0.58
194_D	227_G	0.517	0.58
263_R	299_D	0.516	0.57
22_A	101_P	0.516	0.57
85_I	121_L	0.515	0.57
46_L	49_T	0.514	0.57
2_R	291_S	0.514	0.57
187_A	212_I	0.513	0.57
110_I	113_A	0.511	0.57
48_E	51_R	0.511	0.57
202_V	207_G	0.511	0.57
364_A	449_V	0.510	0.57
15_N	18_A	0.510	0.57
294_A	298_L	0.509	0.56
411_W	452_V	0.509	0.56
257_R	260_A	0.508	0.56
454_M	468_K	0.508	0.56
414_H	441_V	0.508	0.56
174_L	182_V	0.507	0.56
64_M	409_L	0.506	0.56
234_G	409_L	0.506	0.56
107_S	150_S	0.506	0.56
238_A	272_A	0.505	0.56
453_G	464_T	0.504	0.56
270_I	409_L	0.503	0.55
36_S	65_L	0.503	0.55
268_P	302_D	0.502	0.55
163_V	190_V	0.501	0.55
149_G	152_K	0.501	0.55
147_S	281_H	0.500	0.55
123_D	241_D	0.500	0.55

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2e28A	3	0.9914	100	0.175	Contact Map
3t05A	3	0.9896	100	0.178	Contact Map
3gr4A	4	0.8117	100	0.283	Contact Map
1a3wA	3	0.8066	100	0.285	Contact Map
3gg8A	3	0.8083	100	0.286	Contact Map
1e0tA	3	0.7617	100	0.289	Contact Map
3khdA	3	0.81	100	0.29	Contact Map
4kctB	3	0.81	100	0.305	Contact Map
4drsA	3	0.7945	100	0.316	Contact Map
3qtgA	3	0.7634	100	0.324	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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