GREMLIN Database
SYM - Methionine--tRNA ligase
UniProt: Q9HSA4 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 689 (543)
Sequences: 11771 (5777)
Seq/√Len: 247.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
43_L48_Q5.6651.00
337_R343_K3.6611.00
204_E208_G3.6111.00
73_G76_D3.5651.00
433_D449_R3.4411.00
134_D183_T3.4351.00
46_L435_E3.3331.00
208_G212_R3.2521.00
117_A120_D3.1441.00
121_N317_G3.0601.00
486_K490_V3.0481.00
38_A367_A3.0201.00
66_Q69_E3.0171.00
165_G169_H2.9351.00
288_W315_L2.9291.00
436_D440_E2.8801.00
198_R201_D2.7611.00
113_E117_A2.7571.00
10_D48_Q2.6901.00
211_N220_K2.6841.00
425_T530_G2.6131.00
211_N224_R2.5611.00
137_A183_T2.5601.00
134_D180_S2.5171.00
128_E191_E2.5031.00
128_E193_A2.4951.00
126_E193_A2.4731.00
421_D526_P2.4541.00
134_D137_A2.4411.00
116_G120_D2.4271.00
295_I324_R2.4231.00
432_D436_D2.4221.00
86_A90_E2.4031.00
70_A80_E2.3601.00
427_I487_A2.3591.00
435_E518_I2.3541.00
91_E354_D2.3521.00
152_Y174_E2.3441.00
180_S183_T2.3151.00
43_L46_L2.2701.00
211_N228_E2.2531.00
49_E287_V2.2191.00
107_N268_A2.1821.00
24_D84_Q2.1811.00
136_D185_N2.1701.00
40_S50_T2.1441.00
117_A121_N2.1241.00
208_G211_N2.1201.00
429_Q530_G2.1061.00
207_E228_E2.0911.00
93_S498_E2.0871.00
426_E455_R2.0801.00
160_D163_D2.0681.00
399_A503_L2.0581.00
6_Y9_D2.0541.00
42_A46_L2.0471.00
438_L495_F2.0311.00
157_A160_D2.0081.00
435_E439_N1.9971.00
207_E224_R1.9961.00
14_V40_S1.9891.00
431_M491_L1.9821.00
442_D445_T1.9801.00
245_D251_G1.9801.00
205_Y319_D1.9491.00
334_I379_S1.9461.00
44_R95_A1.9351.00
49_E286_S1.9351.00
42_A435_E1.9311.00
492_L500_T1.9221.00
137_A180_S1.9161.00
200_S204_E1.8961.00
11_P49_E1.8851.00
392_A496_L1.8721.00
281_E285_A1.8711.00
334_I381_A1.8691.00
423_V484_L1.8631.00
325_A441_Y1.8601.00
217_N220_K1.8221.00
446_A495_F1.8161.00
83_E86_A1.8151.00
470_D473_A1.8081.00
399_A485_V1.7871.00
136_D183_T1.7801.00
160_D165_G1.7171.00
130_Q191_E1.7001.00
209_F212_R1.6971.00
526_P529_F1.6761.00
420_T460_Y1.6711.00
161_E166_C1.6701.00
45_K490_V1.6681.00
554_K557_A1.6611.00
205_Y208_G1.6551.00
454_A488_V1.6441.00
430_A453_L1.6431.00
352_Y362_L1.6421.00
351_E354_D1.6301.00
41_R497_P1.6171.00
282_F285_A1.6151.00
555_I559_S1.6141.00
72_V76_D1.6101.00
42_A439_N1.6091.00
424_E483_Q1.6031.00
426_E429_Q1.5941.00
517_T520_D1.5941.00
431_M487_A1.5901.00
437_A449_R1.5891.00
43_L439_N1.5781.00
545_T549_E1.5761.00
304_I328_A1.5681.00
221_N225_E1.5681.00
198_R233_D1.5661.00
544_V548_D1.5501.00
161_E165_G1.5441.00
410_F413_T1.5411.00
425_T429_Q1.5371.00
109_E275_E1.5361.00
350_A354_D1.5341.00
543_R546_E1.5251.00
276_R285_A1.5171.00
490_V516_A1.5081.00
271_K274_S1.5011.00
220_K224_R1.5011.00
157_A161_E1.4971.00
392_A499_K1.4961.00
84_Q87_D1.4941.00
76_D80_E1.4921.00
432_D521_C1.4891.00
215_G312_P1.4751.00
58_M103_D1.4711.00
486_K509_E1.4591.00
135_P185_N1.4461.00
150_C176_E1.4261.00
449_R452_A1.4241.00
501_E512_R1.4151.00
33_Y89_F1.4121.00
489_A513_V1.4071.00
46_L439_N1.4061.00
512_R515_D1.3901.00
33_Y94_V1.3751.00
545_T553_A1.3721.00
100_G106_T1.3711.00
428_A431_M1.3681.00
201_D204_E1.3671.00
487_A491_L1.3631.00
545_T548_D1.3611.00
427_I431_M1.3521.00
429_Q433_D1.3401.00
437_A445_T1.3381.00
118_W317_G1.3331.00
166_C169_H1.3331.00
167_Q170_L1.3231.00
64_A68_I1.3201.00
487_A490_V1.3191.00
438_L446_A1.3181.00
105_E109_E1.3181.00
180_S185_N1.3171.00
156_H160_D1.3171.00
467_W477_V1.3091.00
415_Q418_S1.3081.00
224_R228_E1.3061.00
432_D523_Q1.3021.00
489_A503_L1.3021.00
203_Q207_E1.2961.00
427_I484_L1.2951.00
381_A384_A1.2931.00
179_V186_S1.2931.00
250_G253_D1.2901.00
209_F316_A1.2881.00
132_A189_Y1.2771.00
429_Q527_A1.2771.00
123_H202_F1.2711.00
214_E325_A1.2701.00
70_A73_G1.2661.00
83_E87_D1.2651.00
492_L496_L1.2561.00
406_A482_V1.2551.00
76_D79_L1.2471.00
87_D90_E1.2441.00
556_E559_S1.2441.00
433_D436_D1.2351.00
36_G298_V1.2321.00
45_K493_Q1.2211.00
426_E430_A1.2201.00
39_F43_L1.2191.00
205_Y316_A1.2181.00
86_A99_Y1.2171.00
548_D553_A1.2161.00
501_E505_A1.2151.00
430_A449_R1.2101.00
457_G484_L1.2101.00
167_Q173_G1.2091.00
474_A478_M1.2051.00
123_H201_D1.2011.00
510_D516_A1.1931.00
431_M435_E1.1931.00
75_L79_L1.1911.00
557_A560_S1.1841.00
124_V236_I1.1831.00
32_T329_T1.1821.00
71_G74_P1.1661.00
528_E532_P1.1621.00
348_W351_E1.1601.00
169_H173_G1.1531.00
12_A296_I1.1511.00
152_Y172_P1.1501.00
53_V269_A1.1491.00
464_N477_V1.1461.00
114_F318_A1.1421.00
548_D551_L1.1391.00
147_E181_T1.1391.00
336_G344_N1.1351.00
9_D49_E1.1321.00
56_T86_A1.1301.00
547_L551_L1.1281.00
493_Q514_S1.1281.00
471_S474_A1.1281.00
165_G168_R1.1271.00
321_A324_R1.1211.00
450_A492_L1.1181.00
134_D185_N1.1161.00
25_L29_H1.1141.00
465_E468_N1.1121.00
118_W314_M1.1121.00
82_H101_H1.1111.00
136_D180_S1.1101.00
87_D91_E1.1051.00
151_P179_V1.1051.00
80_E83_E1.1051.00
420_T476_P1.1051.00
148_G176_E1.1041.00
197_L236_I1.1021.00
434_Y446_A1.1021.00
296_I325_A1.0951.00
79_L83_E1.0951.00
101_H104_E1.0921.00
476_P480_D1.0901.00
410_F475_A1.0831.00
308_T326_V1.0801.00
80_E84_Q1.0791.00
548_D552_A1.0781.00
489_A500_T1.0741.00
150_C174_E1.0711.00
546_E550_A1.0701.00
364_Y447_G1.0671.00
6_Y49_E1.0651.00
39_F296_I1.0621.00
82_H86_A1.0611.00
130_Q189_Y1.0571.00
398_F457_G1.0551.00
107_N265_E1.0501.00
244_I261_D1.0471.00
430_A434_Y1.0411.00
148_G179_V1.0411.00
91_E350_A1.0411.00
129_I196_F1.0381.00
551_L554_K1.0381.00
515_D518_I1.0361.00
534_E537_E1.0351.00
236_I256_L1.0331.00
434_Y491_L1.0301.00
207_E211_N1.0281.00
283_D286_S1.0271.00
154_G176_E1.0241.00
483_Q487_A1.0211.00
263_P314_M1.0191.00
553_A558_A1.0181.00
546_E549_E1.0171.00
409_N413_T1.0171.00
332_V376_V1.0161.00
12_A39_F1.0151.00
89_F94_V1.0111.00
42_A438_L1.0071.00
518_I521_C1.0021.00
105_E108_V1.0011.00
299_I308_T0.9991.00
533_A536_F0.9971.00
549_E552_A0.9841.00
38_A438_L0.9831.00
132_A146_V0.9821.00
16_C52_F0.9801.00
137_A185_N0.9791.00
266_Y288_W0.9781.00
431_M519_A0.9721.00
424_E480_D0.9691.00
545_T552_A0.9681.00
433_D437_A0.9661.00
511_G515_D0.9661.00
365_Y386_R0.9631.00
66_Q70_A0.9601.00
427_I453_L0.9601.00
425_T525_P0.9581.00
401_R464_N0.9561.00
34_V38_A0.9551.00
109_E112_R0.9521.00
434_Y450_A0.9511.00
77_L81_R0.9511.00
111_T256_L0.9461.00
125_Y198_R0.9451.00
40_S95_A0.9431.00
368_T447_G0.9421.00
480_D484_L0.9401.00
528_E531_E0.9401.00
423_V453_L0.9381.00
426_E456_F0.9341.00
39_F443_L0.9311.00
227_I309_V0.9301.00
98_T104_E0.9281.00
428_A432_D0.9261.00
426_E534_E0.9251.00
81_R84_Q0.9241.00
447_G495_F0.9231.00
8_T49_E0.9221.00
46_L520_D0.9191.00
110_L113_E0.9131.00
527_A531_E0.9121.00
281_E284_W0.9121.00
24_D88_T0.9071.00
423_V456_F0.9061.00
207_E227_I0.9061.00
225_E228_E0.9041.00
135_P188_E0.9031.00
437_A440_E0.9011.00
227_I312_P0.8991.00
434_Y449_R0.8971.00
7_P10_D0.8971.00
418_S472_E0.8961.00
89_F96_F0.8941.00
148_G178_P0.8941.00
296_I327_C0.8941.00
448_E452_A0.8921.00
16_C36_G0.8911.00
467_W473_A0.8851.00
79_L103_D0.8831.00
163_D172_P0.8811.00
16_C33_Y0.8801.00
432_D525_P0.8801.00
154_G158_R0.8801.00
560_S563_A0.8791.00
221_N224_R0.8761.00
534_E538_K0.8751.00
511_G516_A0.8751.00
16_C96_F0.8710.99
239_D254_L0.8700.99
112_R116_G0.8700.99
435_E520_D0.8690.99
27_I332_V0.8670.99
527_A530_G0.8630.99
11_P286_S0.8610.99
125_Y233_D0.8580.99
428_A522_L0.8580.99
7_P49_E0.8570.99
437_A446_A0.8560.99
204_E207_E0.8560.99
496_L499_K0.8530.99
364_Y496_L0.8510.99
302_D331_F0.8500.99
167_Q171_E0.8490.99
430_A491_L0.8480.99
115_V256_L0.8470.99
9_D48_Q0.8460.99
16_C89_F0.8460.99
428_A523_Q0.8440.99
276_R281_E0.8430.99
395_V489_A0.8430.99
536_F540_E0.8410.99
149_T184_G0.8410.99
545_T555_I0.8410.99
179_V184_G0.8400.99
421_D425_T0.8400.99
428_A525_P0.8380.99
334_I337_R0.8360.99
27_I346_A0.8320.99
98_T106_T0.8300.99
553_A559_S0.8290.99
433_D445_T0.8280.99
35_S298_V0.8250.99
34_V367_A0.8210.99
473_A476_P0.8190.99
420_T477_V0.8180.99
353_L359_P0.8180.99
552_A556_E0.8170.99
171_E174_E0.8150.99
475_A478_M0.8150.99
100_G107_N0.8110.99
543_R548_D0.8100.99
493_Q500_T0.8090.99
548_D559_S0.8080.99
266_Y315_L0.8060.99
545_T563_A0.8040.99
549_E553_A0.8040.99
110_L271_K0.8030.99
556_E560_S0.8030.99
210_I224_R0.8020.99
10_D43_L0.7970.99
111_T244_I0.7950.99
197_L260_V0.7950.99
339_L346_A0.7950.99
184_G343_K0.7950.99
469_L474_A0.7920.99
245_D253_D0.7920.99
215_G326_V0.7900.99
52_F96_F0.7900.99
548_D556_E0.7880.99
15_T265_E0.7880.99
502_T505_A0.7880.99
535_L538_K0.7880.99
274_S281_E0.7870.99
420_T467_W0.7850.99
18_L107_N0.7830.99
553_A557_A0.7810.99
30_L92_F0.7810.99
170_L173_G0.7790.99
11_P295_I0.7770.99
540_E545_T0.7750.99
219_A328_A0.7750.99
339_L345_R0.7730.99
378_F383_F0.7730.99
140_W235_C0.7700.99
553_A563_A0.7690.99
60_G64_A0.7680.99
545_T559_S0.7660.99
429_Q432_D0.7660.99
56_T99_Y0.7650.99
334_I380_W0.7640.99
398_F461_I0.7640.99
395_V488_V0.7620.99
194_H235_C0.7620.99
215_G223_P0.7620.99
46_L518_I0.7610.99
282_F286_S0.7600.99
489_A504_W0.7600.99
422_D426_E0.7590.99
206_L209_F0.7590.99
111_T261_D0.7570.99
493_Q504_W0.7570.99
45_K517_T0.7560.99
44_R50_T0.7560.99
548_D554_K0.7530.99
184_G342_S0.7520.98
285_A289_K0.7520.98
538_K541_D0.7510.98
545_T554_K0.7490.98
78_G82_H0.7490.98
552_A555_I0.7490.98
425_T428_A0.7480.98
548_D557_A0.7480.98
549_E558_A0.7470.98
200_S233_D0.7470.98
158_R161_E0.7460.98
258_V261_D0.7450.98
549_E555_I0.7440.98
473_A477_V0.7430.98
98_T283_D0.7430.98
544_V551_L0.7430.98
39_F441_Y0.7420.98
543_R547_L0.7420.98
91_E353_L0.7410.98
402_A481_C0.7410.98
428_A524_A0.7400.98
114_F260_V0.7390.98
426_E530_G0.7390.98
276_R282_F0.7380.98
462_Q465_E0.7370.98
548_D558_A0.7360.98
119_E124_V0.7350.98
301_R331_F0.7340.98
551_L555_I0.7310.98
210_I215_G0.7310.98
119_E248_G0.7300.98
368_T386_R0.7280.98
320_Y324_R0.7280.98
87_D350_A0.7270.98
430_A433_D0.7270.98
13_V270_T0.7260.98
12_A441_Y0.7260.98
482_V486_K0.7260.98
519_A522_L0.7260.98
401_R405_F0.7250.98
485_V507_L0.7220.98
33_Y96_F0.7220.98
296_I441_Y0.7200.98
459_E537_E0.7180.98
477_V480_D0.7180.98
6_Y44_R0.7180.98
115_V124_V0.7180.98
67_A74_P0.7180.98
249_E252_D0.7160.98
35_S367_A0.7150.98
149_T179_V0.7140.98
498_E502_T0.7140.98
11_P287_V0.7120.98
516_A519_A0.7110.98
121_N319_D0.7080.98
13_V295_I0.7070.98
551_L559_S0.7070.98
288_W320_Y0.7060.98
40_S44_R0.7060.98
431_M521_C0.7010.98
472_E476_P0.7010.98
537_E541_D0.6990.98
51_V287_V0.6970.98
205_Y209_F0.6960.98
450_A488_V0.6950.97
206_L313_S0.6910.97
526_P530_G0.6900.97
309_V313_S0.6890.97
129_I235_C0.6890.97
429_Q525_P0.6880.97
419_L464_N0.6880.97
558_A562_D0.6870.97
343_K346_A0.6860.97
209_F213_M0.6840.97
424_E524_A0.6840.97
555_I560_S0.6830.97
209_F321_A0.6820.97
405_F478_M0.6800.97
222_Q225_E0.6800.97
38_A495_F0.6790.97
210_I227_I0.6790.97
88_T348_W0.6760.97
423_V480_D0.6760.97
139_Q183_T0.6750.97
559_S563_A0.6740.97
504_W516_A0.6740.97
544_V549_E0.6740.97
436_D439_N0.6740.97
284_W320_Y0.6730.97
159_G172_P0.6720.97
548_D563_A0.6720.97
382_E385_Q0.6710.97
395_V503_L0.6710.97
420_T480_D0.6710.97
395_V454_A0.6660.97
65_V69_E0.6650.97
537_E540_E0.6640.97
545_T551_L0.6620.97
424_E428_A0.6620.97
219_A222_Q0.6610.97
459_E463_H0.6600.97
352_Y380_W0.6600.97
31_R376_V0.6590.97
555_I558_A0.6590.97
336_G377_N0.6570.96
156_H172_P0.6560.96
548_D555_I0.6550.96
62_P182_I0.6530.96
45_K494_P0.6530.96
450_A491_L0.6530.96
546_E551_L0.6520.96
150_C153_C0.6510.96
152_Y168_R0.6500.96
550_A553_A0.6490.96
199_L231_L0.6470.96
116_G119_E0.6460.96
484_L487_A0.6460.96
15_T290_D0.6450.96
176_E179_V0.6450.96
475_A479_R0.6440.96
100_G265_E0.6440.96
122_D198_R0.6440.96
133_Y138_D0.6440.96
445_T448_E0.6440.96
428_A521_C0.6410.96
409_N412_G0.6410.96
533_A537_E0.6410.96
557_A562_D0.6400.96
547_L554_K0.6400.96
493_Q513_V0.6400.96
557_A561_E0.6390.96
532_P548_D0.6380.96
464_N467_W0.6380.96
493_Q501_E0.6360.96
367_A495_F0.6350.96
10_D49_E0.6340.96
414_P417_V0.6340.96
114_F264_I0.6330.96
118_W197_L0.6320.96
41_R95_A0.6320.96
544_V552_A0.6320.96
484_L488_V0.6310.96
31_R332_V0.6270.95
156_H163_D0.6260.95
213_M220_K0.6260.95
264_I314_M0.6250.95
7_P286_S0.6240.95
127_T196_F0.6230.95
470_D474_A0.6230.95
395_V499_K0.6220.95
137_A184_G0.6220.95
471_S475_A0.6220.95
536_F539_I0.6210.95
409_N478_M0.6210.95
445_T449_R0.6200.95
431_M434_Y0.6200.95
206_L312_P0.6200.95
79_L101_H0.6200.95
36_G52_F0.6190.95
554_K559_S0.6180.95
60_G74_P0.6170.95
502_T506_Q0.6170.95
202_F317_G0.6130.95
124_V197_L0.6120.95
66_Q342_S0.6090.95
25_L85_Y0.6080.95
335_D346_A0.6070.95
540_E544_V0.6060.95
333_N337_R0.6060.95
10_D295_I0.6040.94
146_V187_A0.6040.94
212_R320_Y0.6040.94
213_M321_A0.6030.94
552_A557_A0.6020.94
532_P536_F0.6020.94
58_M101_H0.6010.94
298_V329_T0.6010.94
334_I344_N0.6010.94
300_G329_T0.6000.94
533_A540_E0.6000.94
12_A43_L0.6000.94
109_E113_E0.5990.94
223_P326_V0.5980.94
346_A349_A0.5980.94
434_Y438_L0.5970.94
540_E548_D0.5960.94
548_D562_D0.5960.94
403_L407_N0.5950.94
553_A556_E0.5950.94
427_I480_D0.5950.94
352_Y378_F0.5940.94
273_Y276_R0.5940.94
544_V547_L0.5930.94
266_Y314_M0.5930.94
499_K502_T0.5920.94
199_L202_F0.5920.94
300_G331_F0.5920.94
333_N377_N0.5910.94
267_V288_W0.5900.94
370_S376_V0.5900.94
297_H311_W0.5890.94
549_E554_K0.5890.94
546_E557_A0.5890.94
206_L309_V0.5880.94
121_N318_A0.5870.94
424_E484_L0.5870.94
551_L556_E0.5870.94
554_K558_A0.5860.94
408_R478_M0.5860.94
333_N344_N0.5860.94
98_T272_Q0.5840.93
106_T275_E0.5840.93
543_R558_A0.5830.93
200_S203_Q0.5820.93
402_A456_F0.5810.93
127_T233_D0.5800.93
419_L463_H0.5800.93
71_G75_L0.5790.93
549_E559_S0.5770.93
347_I352_Y0.5770.93
43_L50_T0.5760.93
515_D521_C0.5760.93
546_E558_A0.5750.93
118_W121_N0.5750.93
399_A403_L0.5750.93
502_T533_A0.5750.93
72_V77_L0.5740.93
464_N473_A0.5740.93
469_L477_V0.5720.93
60_G68_I0.5720.93
23_G29_H0.5720.93
217_N221_N0.5710.93
531_E534_E0.5710.93
434_Y518_I0.5710.93
558_A563_A0.5700.93
214_E220_K0.5700.93
330_G374_R0.5670.92
478_M482_V0.5670.92
32_T36_G0.5670.92
13_V287_V0.5660.92
518_I522_L0.5660.92
396_G499_K0.5660.92
88_T350_A0.5660.92
558_A561_E0.5650.92
131_V141_L0.5640.92
210_I220_K0.5640.92
557_A563_A0.5630.92
180_S184_G0.5630.92
335_D344_N0.5610.92
311_W323_P0.5610.92
256_L260_V0.5610.92
505_A512_R0.5610.92
35_S443_L0.5600.92
142_P145_Y0.5590.92
24_D81_R0.5570.92
395_V492_L0.5570.92
365_Y382_E0.5560.92
331_F338_G0.5560.92
64_A241_D0.5550.92
394_A454_A0.5540.91
175_I179_V0.5540.91
148_G175_I0.5540.91
53_V270_T0.5540.91
75_L78_G0.5540.91
149_T177_A0.5540.91
497_P500_T0.5530.91
367_A447_G0.5530.91
68_I74_P0.5530.91
72_V80_E0.5530.91
437_A442_D0.5530.91
403_L506_Q0.5520.91
400_Y403_L0.5510.91
479_R483_Q0.5510.91
543_R549_E0.5500.91
131_V140_W0.5500.91
312_P321_A0.5490.91
114_F118_W0.5490.91
423_V460_Y0.5480.91
546_E552_A0.5480.91
199_L313_S0.5480.91
406_A478_M0.5470.91
351_E380_W0.5450.91
9_D517_T0.5450.91
531_E535_L0.5440.91
409_N479_R0.5440.91
547_L550_A0.5430.91
66_Q81_R0.5430.91
108_V112_R0.5420.91
95_A514_S0.5420.91
194_H239_D0.5410.91
426_E453_L0.5410.91
401_R461_I0.5390.90
400_Y506_Q0.5390.90
402_A485_V0.5380.90
425_T527_A0.5370.90
62_P181_T0.5360.90
543_R559_S0.5350.90
51_V283_D0.5330.90
382_E386_R0.5330.90
218_N301_R0.5320.90
56_T82_H0.5300.90
438_L518_I0.5300.90
545_T550_A0.5300.90
349_A352_Y0.5300.90
48_Q439_N0.5300.90
428_A487_A0.5300.90
459_E462_Q0.5300.90
246_Y256_L0.5300.90
121_N316_A0.5290.90
425_T524_A0.5280.89
114_F267_V0.5280.89
32_T35_S0.5280.89
333_N336_G0.5260.89
158_R162_C0.5260.89
545_T562_D0.5260.89
456_F459_E0.5260.89
399_A506_Q0.5250.89
270_T287_V0.5250.89
271_K283_D0.5230.89
421_D424_E0.5230.89
112_R245_D0.5230.89
425_T526_P0.5210.89
210_I213_M0.5200.89
159_G163_D0.5200.89
380_W384_A0.5200.89
535_L539_I0.5180.89
202_F206_L0.5180.89
141_L180_S0.5170.88
389_T393_D0.5170.88
276_R286_S0.5170.88
399_A402_A0.5160.88
249_E253_D0.5160.88
163_D169_H0.5160.88
109_E271_K0.5160.88
132_A187_A0.5140.88
237_T246_Y0.5140.88
486_K508_G0.5110.88
223_P312_P0.5110.88
525_P530_G0.5110.88
427_I430_A0.5110.88
301_R328_A0.5110.88
275_E281_E0.5100.88
357_F383_F0.5090.88
108_V245_D0.5090.88
80_E87_D0.5090.88
544_V553_A0.5080.88
129_I192_R0.5080.88
398_F454_A0.5080.88
62_P142_P0.5080.88
483_Q486_K0.5080.88
316_A321_A0.5070.87
231_L313_S0.5070.87
504_W508_G0.5070.87
339_L344_N0.5060.87
410_F414_P0.5060.87
482_V508_G0.5060.87
347_I378_F0.5050.87
218_N221_N0.5050.87
27_I362_L0.5040.87
559_S562_D0.5040.87
32_T298_V0.5040.87
214_E440_E0.5040.87
54_S96_F0.5040.87
196_F235_C0.5040.87
371_G444_R0.5030.87
45_K518_I0.5020.87
486_K504_W0.5020.87
124_V256_L0.5020.87
66_Q77_L0.5010.87
267_V315_L0.5010.87
543_R551_L0.5010.87
25_L92_F0.5000.87
240_L255_V0.5000.87
65_V137_A0.5000.87
305_Q309_V0.5000.87
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1rqgA 2 0.8142 100 0.204 Contact Map
1gaxA 1 0.9507 100 0.332 Contact Map
1ffyA 1 0.8955 100 0.361 Contact Map
1ileA 1 0.7837 100 0.382 Contact Map
3kflA 1 0.7344 100 0.403 Contact Map
1wz2A 1 0.9231 100 0.412 Contact Map
3h99A 1 0.7692 100 0.413 Contact Map
3ziuA 1 0.7533 100 0.427 Contact Map
4qreA 1 0.7242 100 0.432 Contact Map
4arcA 1 0.7431 100 0.436 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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