SYM - HALSA - GREMLIN Contacts

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SYM - Methionine--tRNA ligase

UniProt:	Q9HSA4	Sequences: MTDEDYPTDDPAVVTCGLPYPTGDLHIGHLRTYVSGDAFSRALRKLGQETVFVSGTDMHGTPIAVQAIEAGVGPLDLGLERHEQYADTFEEFSVAFDTYGHTDEETNVELTREFVGAWEDNDHVYETEIQVAYDPDADQWLPDRYVEGTCPYCGEHARGDECDEGCQRHLEPGEIEAPVSTITGNSAEYHERAHKFLRLSDFQEYLEGFINRMEGTNNAKNQPREWIEGGLEDFCITRDLDWGIDYPGEGGDDLVLYVWVDAPIEYVAATKQYSERVGTEEFDWASVWKDGDGEIIHVIGRDIIQHHTVFWPSMLAGADYAEPRAVCATGFVNIDGRGLSTSKNRAIWAAEYLDAGFHPDLLRYYLATASGFERDVNFSWAEFAQRVNTELADAVGNFAYRALLFANRNFDGTPQEVSLTDDVETEIAQAMDDYEDALNEYDLRTAGERAVALARFGNEYIQHNEPWNLDSEAAAPVMRDCVQLVKAVAVLLQPFLPEKTETLWAQLGEDGRVSDATIADCLQAPPAEFGEPAELFEKIEDDRVTELDEALAAKIEAASSEDADGEGMADETADDGIELEPLAEDDISFEEFQALDLRVGEVVEAEGIEGADDLARLEVDIGHEVRQIVAGIKQLHDLDALPGTRVVVVANMEPSELFGVESNGMVLAAGEDADLLTTHEDSEPGTKVM	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	689 (543)
Sequences:	11771 (5777)
Seq/√Len:	247.9

ECOLI - SYM SYV SYI SYL
BACSU - SYM SYV SYI SYL
HALSA - SYM SYV SYI SYL
SULSO - SYM SYV SYI SYL2 SYL1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
43_L	48_Q	5.665	1.00
337_R	343_K	3.661	1.00
204_E	208_G	3.611	1.00
73_G	76_D	3.565	1.00
433_D	449_R	3.441	1.00
134_D	183_T	3.435	1.00
46_L	435_E	3.333	1.00
208_G	212_R	3.252	1.00
117_A	120_D	3.144	1.00
121_N	317_G	3.060	1.00
486_K	490_V	3.048	1.00
38_A	367_A	3.020	1.00
66_Q	69_E	3.017	1.00
165_G	169_H	2.935	1.00
288_W	315_L	2.929	1.00
436_D	440_E	2.880	1.00
198_R	201_D	2.761	1.00
113_E	117_A	2.757	1.00
10_D	48_Q	2.690	1.00
211_N	220_K	2.684	1.00
425_T	530_G	2.613	1.00
211_N	224_R	2.561	1.00
137_A	183_T	2.560	1.00
134_D	180_S	2.517	1.00
128_E	191_E	2.503	1.00
128_E	193_A	2.495	1.00
126_E	193_A	2.473	1.00
421_D	526_P	2.454	1.00
134_D	137_A	2.441	1.00
116_G	120_D	2.427	1.00
295_I	324_R	2.423	1.00
432_D	436_D	2.422	1.00
86_A	90_E	2.403	1.00
70_A	80_E	2.360	1.00
427_I	487_A	2.359	1.00
435_E	518_I	2.354	1.00
91_E	354_D	2.352	1.00
152_Y	174_E	2.344	1.00
180_S	183_T	2.315	1.00
43_L	46_L	2.270	1.00
211_N	228_E	2.253	1.00
49_E	287_V	2.219	1.00
107_N	268_A	2.182	1.00
24_D	84_Q	2.181	1.00
136_D	185_N	2.170	1.00
40_S	50_T	2.144	1.00
117_A	121_N	2.124	1.00
208_G	211_N	2.120	1.00
429_Q	530_G	2.106	1.00
207_E	228_E	2.091	1.00
93_S	498_E	2.087	1.00
426_E	455_R	2.080	1.00
160_D	163_D	2.068	1.00
399_A	503_L	2.058	1.00
6_Y	9_D	2.054	1.00
42_A	46_L	2.047	1.00
438_L	495_F	2.031	1.00
157_A	160_D	2.008	1.00
435_E	439_N	1.997	1.00
207_E	224_R	1.996	1.00
14_V	40_S	1.989	1.00
431_M	491_L	1.982	1.00
442_D	445_T	1.980	1.00
245_D	251_G	1.980	1.00
205_Y	319_D	1.949	1.00
334_I	379_S	1.946	1.00
44_R	95_A	1.935	1.00
49_E	286_S	1.935	1.00
42_A	435_E	1.931	1.00
492_L	500_T	1.922	1.00
137_A	180_S	1.916	1.00
200_S	204_E	1.896	1.00
11_P	49_E	1.885	1.00
392_A	496_L	1.872	1.00
281_E	285_A	1.871	1.00
334_I	381_A	1.869	1.00
423_V	484_L	1.863	1.00
325_A	441_Y	1.860	1.00
217_N	220_K	1.822	1.00
446_A	495_F	1.816	1.00
83_E	86_A	1.815	1.00
470_D	473_A	1.808	1.00
399_A	485_V	1.787	1.00
136_D	183_T	1.780	1.00
160_D	165_G	1.717	1.00
130_Q	191_E	1.700	1.00
209_F	212_R	1.697	1.00
526_P	529_F	1.676	1.00
420_T	460_Y	1.671	1.00
161_E	166_C	1.670	1.00
45_K	490_V	1.668	1.00
554_K	557_A	1.661	1.00
205_Y	208_G	1.655	1.00
454_A	488_V	1.644	1.00
430_A	453_L	1.643	1.00
352_Y	362_L	1.642	1.00
351_E	354_D	1.630	1.00
41_R	497_P	1.617	1.00
282_F	285_A	1.615	1.00
555_I	559_S	1.614	1.00
72_V	76_D	1.610	1.00
42_A	439_N	1.609	1.00
424_E	483_Q	1.603	1.00
426_E	429_Q	1.594	1.00
517_T	520_D	1.594	1.00
431_M	487_A	1.590	1.00
437_A	449_R	1.589	1.00
43_L	439_N	1.578	1.00
545_T	549_E	1.576	1.00
304_I	328_A	1.568	1.00
221_N	225_E	1.568	1.00
198_R	233_D	1.566	1.00
544_V	548_D	1.550	1.00
161_E	165_G	1.544	1.00
410_F	413_T	1.541	1.00
425_T	429_Q	1.537	1.00
109_E	275_E	1.536	1.00
350_A	354_D	1.534	1.00
543_R	546_E	1.525	1.00
276_R	285_A	1.517	1.00
490_V	516_A	1.508	1.00
271_K	274_S	1.501	1.00
220_K	224_R	1.501	1.00
157_A	161_E	1.497	1.00
392_A	499_K	1.496	1.00
84_Q	87_D	1.494	1.00
76_D	80_E	1.492	1.00
432_D	521_C	1.489	1.00
215_G	312_P	1.475	1.00
58_M	103_D	1.471	1.00
486_K	509_E	1.459	1.00
135_P	185_N	1.446	1.00
150_C	176_E	1.426	1.00
449_R	452_A	1.424	1.00
501_E	512_R	1.415	1.00
33_Y	89_F	1.412	1.00
489_A	513_V	1.407	1.00
46_L	439_N	1.406	1.00
512_R	515_D	1.390	1.00
33_Y	94_V	1.375	1.00
545_T	553_A	1.372	1.00
100_G	106_T	1.371	1.00
428_A	431_M	1.368	1.00
201_D	204_E	1.367	1.00
487_A	491_L	1.363	1.00
545_T	548_D	1.361	1.00
427_I	431_M	1.352	1.00
429_Q	433_D	1.340	1.00
437_A	445_T	1.338	1.00
118_W	317_G	1.333	1.00
166_C	169_H	1.333	1.00
167_Q	170_L	1.323	1.00
64_A	68_I	1.320	1.00
487_A	490_V	1.319	1.00
438_L	446_A	1.318	1.00
105_E	109_E	1.318	1.00
180_S	185_N	1.317	1.00
156_H	160_D	1.317	1.00
467_W	477_V	1.309	1.00
415_Q	418_S	1.308	1.00
224_R	228_E	1.306	1.00
432_D	523_Q	1.302	1.00
489_A	503_L	1.302	1.00
203_Q	207_E	1.296	1.00
427_I	484_L	1.295	1.00
381_A	384_A	1.293	1.00
179_V	186_S	1.293	1.00
250_G	253_D	1.290	1.00
209_F	316_A	1.288	1.00
132_A	189_Y	1.277	1.00
429_Q	527_A	1.277	1.00
123_H	202_F	1.271	1.00
214_E	325_A	1.270	1.00
70_A	73_G	1.266	1.00
83_E	87_D	1.265	1.00
492_L	496_L	1.256	1.00
406_A	482_V	1.255	1.00
76_D	79_L	1.247	1.00
87_D	90_E	1.244	1.00
556_E	559_S	1.244	1.00
433_D	436_D	1.235	1.00
36_G	298_V	1.232	1.00
45_K	493_Q	1.221	1.00
426_E	430_A	1.220	1.00
39_F	43_L	1.219	1.00
205_Y	316_A	1.218	1.00
86_A	99_Y	1.217	1.00
548_D	553_A	1.216	1.00
501_E	505_A	1.215	1.00
430_A	449_R	1.210	1.00
457_G	484_L	1.210	1.00
167_Q	173_G	1.209	1.00
474_A	478_M	1.205	1.00
123_H	201_D	1.201	1.00
510_D	516_A	1.193	1.00
431_M	435_E	1.193	1.00
75_L	79_L	1.191	1.00
557_A	560_S	1.184	1.00
124_V	236_I	1.183	1.00
32_T	329_T	1.182	1.00
71_G	74_P	1.166	1.00
528_E	532_P	1.162	1.00
348_W	351_E	1.160	1.00
169_H	173_G	1.153	1.00
12_A	296_I	1.151	1.00
152_Y	172_P	1.150	1.00
53_V	269_A	1.149	1.00
464_N	477_V	1.146	1.00
114_F	318_A	1.142	1.00
548_D	551_L	1.139	1.00
147_E	181_T	1.139	1.00
336_G	344_N	1.135	1.00
9_D	49_E	1.132	1.00
56_T	86_A	1.130	1.00
547_L	551_L	1.128	1.00
493_Q	514_S	1.128	1.00
471_S	474_A	1.128	1.00
165_G	168_R	1.127	1.00
321_A	324_R	1.121	1.00
450_A	492_L	1.118	1.00
134_D	185_N	1.116	1.00
25_L	29_H	1.114	1.00
465_E	468_N	1.112	1.00
118_W	314_M	1.112	1.00
82_H	101_H	1.111	1.00
136_D	180_S	1.110	1.00
87_D	91_E	1.105	1.00
151_P	179_V	1.105	1.00
80_E	83_E	1.105	1.00
420_T	476_P	1.105	1.00
148_G	176_E	1.104	1.00
197_L	236_I	1.102	1.00
434_Y	446_A	1.102	1.00
296_I	325_A	1.095	1.00
79_L	83_E	1.095	1.00
101_H	104_E	1.092	1.00
476_P	480_D	1.090	1.00
410_F	475_A	1.083	1.00
308_T	326_V	1.080	1.00
80_E	84_Q	1.079	1.00
548_D	552_A	1.078	1.00
489_A	500_T	1.074	1.00
150_C	174_E	1.071	1.00
546_E	550_A	1.070	1.00
364_Y	447_G	1.067	1.00
6_Y	49_E	1.065	1.00
39_F	296_I	1.062	1.00
82_H	86_A	1.061	1.00
130_Q	189_Y	1.057	1.00
398_F	457_G	1.055	1.00
107_N	265_E	1.050	1.00
244_I	261_D	1.047	1.00
430_A	434_Y	1.041	1.00
148_G	179_V	1.041	1.00
91_E	350_A	1.041	1.00
129_I	196_F	1.038	1.00
551_L	554_K	1.038	1.00
515_D	518_I	1.036	1.00
534_E	537_E	1.035	1.00
236_I	256_L	1.033	1.00
434_Y	491_L	1.030	1.00
207_E	211_N	1.028	1.00
283_D	286_S	1.027	1.00
154_G	176_E	1.024	1.00
483_Q	487_A	1.021	1.00
263_P	314_M	1.019	1.00
553_A	558_A	1.018	1.00
546_E	549_E	1.017	1.00
409_N	413_T	1.017	1.00
332_V	376_V	1.016	1.00
12_A	39_F	1.015	1.00
89_F	94_V	1.011	1.00
42_A	438_L	1.007	1.00
518_I	521_C	1.002	1.00
105_E	108_V	1.001	1.00
299_I	308_T	0.999	1.00
533_A	536_F	0.997	1.00
549_E	552_A	0.984	1.00
38_A	438_L	0.983	1.00
132_A	146_V	0.982	1.00
16_C	52_F	0.980	1.00
137_A	185_N	0.979	1.00
266_Y	288_W	0.978	1.00
431_M	519_A	0.972	1.00
424_E	480_D	0.969	1.00
545_T	552_A	0.968	1.00
433_D	437_A	0.966	1.00
511_G	515_D	0.966	1.00
365_Y	386_R	0.963	1.00
66_Q	70_A	0.960	1.00
427_I	453_L	0.960	1.00
425_T	525_P	0.958	1.00
401_R	464_N	0.956	1.00
34_V	38_A	0.955	1.00
109_E	112_R	0.952	1.00
434_Y	450_A	0.951	1.00
77_L	81_R	0.951	1.00
111_T	256_L	0.946	1.00
125_Y	198_R	0.945	1.00
40_S	95_A	0.943	1.00
368_T	447_G	0.942	1.00
480_D	484_L	0.940	1.00
528_E	531_E	0.940	1.00
423_V	453_L	0.938	1.00
426_E	456_F	0.934	1.00
39_F	443_L	0.931	1.00
227_I	309_V	0.930	1.00
98_T	104_E	0.928	1.00
428_A	432_D	0.926	1.00
426_E	534_E	0.925	1.00
81_R	84_Q	0.924	1.00
447_G	495_F	0.923	1.00
8_T	49_E	0.922	1.00
46_L	520_D	0.919	1.00
110_L	113_E	0.913	1.00
527_A	531_E	0.912	1.00
281_E	284_W	0.912	1.00
24_D	88_T	0.907	1.00
423_V	456_F	0.906	1.00
207_E	227_I	0.906	1.00
225_E	228_E	0.904	1.00
135_P	188_E	0.903	1.00
437_A	440_E	0.901	1.00
227_I	312_P	0.899	1.00
434_Y	449_R	0.897	1.00
7_P	10_D	0.897	1.00
418_S	472_E	0.896	1.00
89_F	96_F	0.894	1.00
148_G	178_P	0.894	1.00
296_I	327_C	0.894	1.00
448_E	452_A	0.892	1.00
16_C	36_G	0.891	1.00
467_W	473_A	0.885	1.00
79_L	103_D	0.883	1.00
163_D	172_P	0.881	1.00
16_C	33_Y	0.880	1.00
432_D	525_P	0.880	1.00
154_G	158_R	0.880	1.00
560_S	563_A	0.879	1.00
221_N	224_R	0.876	1.00
534_E	538_K	0.875	1.00
511_G	516_A	0.875	1.00
16_C	96_F	0.871	0.99
239_D	254_L	0.870	0.99
112_R	116_G	0.870	0.99
435_E	520_D	0.869	0.99
27_I	332_V	0.867	0.99
527_A	530_G	0.863	0.99
11_P	286_S	0.861	0.99
125_Y	233_D	0.858	0.99
428_A	522_L	0.858	0.99
7_P	49_E	0.857	0.99
437_A	446_A	0.856	0.99
204_E	207_E	0.856	0.99
496_L	499_K	0.853	0.99
364_Y	496_L	0.851	0.99
302_D	331_F	0.850	0.99
167_Q	171_E	0.849	0.99
430_A	491_L	0.848	0.99
115_V	256_L	0.847	0.99
9_D	48_Q	0.846	0.99
16_C	89_F	0.846	0.99
428_A	523_Q	0.844	0.99
276_R	281_E	0.843	0.99
395_V	489_A	0.843	0.99
536_F	540_E	0.841	0.99
149_T	184_G	0.841	0.99
545_T	555_I	0.841	0.99
179_V	184_G	0.840	0.99
421_D	425_T	0.840	0.99
428_A	525_P	0.838	0.99
334_I	337_R	0.836	0.99
27_I	346_A	0.832	0.99
98_T	106_T	0.830	0.99
553_A	559_S	0.829	0.99
433_D	445_T	0.828	0.99
35_S	298_V	0.825	0.99
34_V	367_A	0.821	0.99
473_A	476_P	0.819	0.99
420_T	477_V	0.818	0.99
353_L	359_P	0.818	0.99
552_A	556_E	0.817	0.99
171_E	174_E	0.815	0.99
475_A	478_M	0.815	0.99
100_G	107_N	0.811	0.99
543_R	548_D	0.810	0.99
493_Q	500_T	0.809	0.99
548_D	559_S	0.808	0.99
266_Y	315_L	0.806	0.99
545_T	563_A	0.804	0.99
549_E	553_A	0.804	0.99
110_L	271_K	0.803	0.99
556_E	560_S	0.803	0.99
210_I	224_R	0.802	0.99
10_D	43_L	0.797	0.99
111_T	244_I	0.795	0.99
197_L	260_V	0.795	0.99
339_L	346_A	0.795	0.99
184_G	343_K	0.795	0.99
469_L	474_A	0.792	0.99
245_D	253_D	0.792	0.99
215_G	326_V	0.790	0.99
52_F	96_F	0.790	0.99
548_D	556_E	0.788	0.99
15_T	265_E	0.788	0.99
502_T	505_A	0.788	0.99
535_L	538_K	0.788	0.99
274_S	281_E	0.787	0.99
420_T	467_W	0.785	0.99
18_L	107_N	0.783	0.99
553_A	557_A	0.781	0.99
30_L	92_F	0.781	0.99
170_L	173_G	0.779	0.99
11_P	295_I	0.777	0.99
540_E	545_T	0.775	0.99
219_A	328_A	0.775	0.99
339_L	345_R	0.773	0.99
378_F	383_F	0.773	0.99
140_W	235_C	0.770	0.99
553_A	563_A	0.769	0.99
60_G	64_A	0.768	0.99
545_T	559_S	0.766	0.99
429_Q	432_D	0.766	0.99
56_T	99_Y	0.765	0.99
334_I	380_W	0.764	0.99
398_F	461_I	0.764	0.99
395_V	488_V	0.762	0.99
194_H	235_C	0.762	0.99
215_G	223_P	0.762	0.99
46_L	518_I	0.761	0.99
282_F	286_S	0.760	0.99
489_A	504_W	0.760	0.99
422_D	426_E	0.759	0.99
206_L	209_F	0.759	0.99
111_T	261_D	0.757	0.99
493_Q	504_W	0.757	0.99
45_K	517_T	0.756	0.99
44_R	50_T	0.756	0.99
548_D	554_K	0.753	0.99
184_G	342_S	0.752	0.98
285_A	289_K	0.752	0.98
538_K	541_D	0.751	0.98
545_T	554_K	0.749	0.98
78_G	82_H	0.749	0.98
552_A	555_I	0.749	0.98
425_T	428_A	0.748	0.98
548_D	557_A	0.748	0.98
549_E	558_A	0.747	0.98
200_S	233_D	0.747	0.98
158_R	161_E	0.746	0.98
258_V	261_D	0.745	0.98
549_E	555_I	0.744	0.98
473_A	477_V	0.743	0.98
98_T	283_D	0.743	0.98
544_V	551_L	0.743	0.98
39_F	441_Y	0.742	0.98
543_R	547_L	0.742	0.98
91_E	353_L	0.741	0.98
402_A	481_C	0.741	0.98
428_A	524_A	0.740	0.98
114_F	260_V	0.739	0.98
426_E	530_G	0.739	0.98
276_R	282_F	0.738	0.98
462_Q	465_E	0.737	0.98
548_D	558_A	0.736	0.98
119_E	124_V	0.735	0.98
301_R	331_F	0.734	0.98
551_L	555_I	0.731	0.98
210_I	215_G	0.731	0.98
119_E	248_G	0.730	0.98
368_T	386_R	0.728	0.98
320_Y	324_R	0.728	0.98
87_D	350_A	0.727	0.98
430_A	433_D	0.727	0.98
13_V	270_T	0.726	0.98
12_A	441_Y	0.726	0.98
482_V	486_K	0.726	0.98
519_A	522_L	0.726	0.98
401_R	405_F	0.725	0.98
485_V	507_L	0.722	0.98
33_Y	96_F	0.722	0.98
296_I	441_Y	0.720	0.98
459_E	537_E	0.718	0.98
477_V	480_D	0.718	0.98
6_Y	44_R	0.718	0.98
115_V	124_V	0.718	0.98
67_A	74_P	0.718	0.98
249_E	252_D	0.716	0.98
35_S	367_A	0.715	0.98
149_T	179_V	0.714	0.98
498_E	502_T	0.714	0.98
11_P	287_V	0.712	0.98
516_A	519_A	0.711	0.98
121_N	319_D	0.708	0.98
13_V	295_I	0.707	0.98
551_L	559_S	0.707	0.98
288_W	320_Y	0.706	0.98
40_S	44_R	0.706	0.98
431_M	521_C	0.701	0.98
472_E	476_P	0.701	0.98
537_E	541_D	0.699	0.98
51_V	287_V	0.697	0.98
205_Y	209_F	0.696	0.98
450_A	488_V	0.695	0.97
206_L	313_S	0.691	0.97
526_P	530_G	0.690	0.97
309_V	313_S	0.689	0.97
129_I	235_C	0.689	0.97
429_Q	525_P	0.688	0.97
419_L	464_N	0.688	0.97
558_A	562_D	0.687	0.97
343_K	346_A	0.686	0.97
209_F	213_M	0.684	0.97
424_E	524_A	0.684	0.97
555_I	560_S	0.683	0.97
209_F	321_A	0.682	0.97
405_F	478_M	0.680	0.97
222_Q	225_E	0.680	0.97
38_A	495_F	0.679	0.97
210_I	227_I	0.679	0.97
88_T	348_W	0.676	0.97
423_V	480_D	0.676	0.97
139_Q	183_T	0.675	0.97
559_S	563_A	0.674	0.97
504_W	516_A	0.674	0.97
544_V	549_E	0.674	0.97
436_D	439_N	0.674	0.97
284_W	320_Y	0.673	0.97
159_G	172_P	0.672	0.97
548_D	563_A	0.672	0.97
382_E	385_Q	0.671	0.97
395_V	503_L	0.671	0.97
420_T	480_D	0.671	0.97
395_V	454_A	0.666	0.97
65_V	69_E	0.665	0.97
537_E	540_E	0.664	0.97
545_T	551_L	0.662	0.97
424_E	428_A	0.662	0.97
219_A	222_Q	0.661	0.97
459_E	463_H	0.660	0.97
352_Y	380_W	0.660	0.97
31_R	376_V	0.659	0.97
555_I	558_A	0.659	0.97
336_G	377_N	0.657	0.96
156_H	172_P	0.656	0.96
548_D	555_I	0.655	0.96
62_P	182_I	0.653	0.96
45_K	494_P	0.653	0.96
450_A	491_L	0.653	0.96
546_E	551_L	0.652	0.96
150_C	153_C	0.651	0.96
152_Y	168_R	0.650	0.96
550_A	553_A	0.649	0.96
199_L	231_L	0.647	0.96
116_G	119_E	0.646	0.96
484_L	487_A	0.646	0.96
15_T	290_D	0.645	0.96
176_E	179_V	0.645	0.96
475_A	479_R	0.644	0.96
100_G	265_E	0.644	0.96
122_D	198_R	0.644	0.96
133_Y	138_D	0.644	0.96
445_T	448_E	0.644	0.96
428_A	521_C	0.641	0.96
409_N	412_G	0.641	0.96
533_A	537_E	0.641	0.96
557_A	562_D	0.640	0.96
547_L	554_K	0.640	0.96
493_Q	513_V	0.640	0.96
557_A	561_E	0.639	0.96
532_P	548_D	0.638	0.96
464_N	467_W	0.638	0.96
493_Q	501_E	0.636	0.96
367_A	495_F	0.635	0.96
10_D	49_E	0.634	0.96
414_P	417_V	0.634	0.96
114_F	264_I	0.633	0.96
118_W	197_L	0.632	0.96
41_R	95_A	0.632	0.96
544_V	552_A	0.632	0.96
484_L	488_V	0.631	0.96
31_R	332_V	0.627	0.95
156_H	163_D	0.626	0.95
213_M	220_K	0.626	0.95
264_I	314_M	0.625	0.95
7_P	286_S	0.624	0.95
127_T	196_F	0.623	0.95
470_D	474_A	0.623	0.95
395_V	499_K	0.622	0.95
137_A	184_G	0.622	0.95
471_S	475_A	0.622	0.95
536_F	539_I	0.621	0.95
409_N	478_M	0.621	0.95
445_T	449_R	0.620	0.95
431_M	434_Y	0.620	0.95
206_L	312_P	0.620	0.95
79_L	101_H	0.620	0.95
36_G	52_F	0.619	0.95
554_K	559_S	0.618	0.95
60_G	74_P	0.617	0.95
502_T	506_Q	0.617	0.95
202_F	317_G	0.613	0.95
124_V	197_L	0.612	0.95
66_Q	342_S	0.609	0.95
25_L	85_Y	0.608	0.95
335_D	346_A	0.607	0.95
540_E	544_V	0.606	0.95
333_N	337_R	0.606	0.95
10_D	295_I	0.604	0.94
146_V	187_A	0.604	0.94
212_R	320_Y	0.604	0.94
213_M	321_A	0.603	0.94
552_A	557_A	0.602	0.94
532_P	536_F	0.602	0.94
58_M	101_H	0.601	0.94
298_V	329_T	0.601	0.94
334_I	344_N	0.601	0.94
300_G	329_T	0.600	0.94
533_A	540_E	0.600	0.94
12_A	43_L	0.600	0.94
109_E	113_E	0.599	0.94
223_P	326_V	0.598	0.94
346_A	349_A	0.598	0.94
434_Y	438_L	0.597	0.94
540_E	548_D	0.596	0.94
548_D	562_D	0.596	0.94
403_L	407_N	0.595	0.94
553_A	556_E	0.595	0.94
427_I	480_D	0.595	0.94
352_Y	378_F	0.594	0.94
273_Y	276_R	0.594	0.94
544_V	547_L	0.593	0.94
266_Y	314_M	0.593	0.94
499_K	502_T	0.592	0.94
199_L	202_F	0.592	0.94
300_G	331_F	0.592	0.94
333_N	377_N	0.591	0.94
267_V	288_W	0.590	0.94
370_S	376_V	0.590	0.94
297_H	311_W	0.589	0.94
549_E	554_K	0.589	0.94
546_E	557_A	0.589	0.94
206_L	309_V	0.588	0.94
121_N	318_A	0.587	0.94
424_E	484_L	0.587	0.94
551_L	556_E	0.587	0.94
554_K	558_A	0.586	0.94
408_R	478_M	0.586	0.94
333_N	344_N	0.586	0.94
98_T	272_Q	0.584	0.93
106_T	275_E	0.584	0.93
543_R	558_A	0.583	0.93
200_S	203_Q	0.582	0.93
402_A	456_F	0.581	0.93
127_T	233_D	0.580	0.93
419_L	463_H	0.580	0.93
71_G	75_L	0.579	0.93
549_E	559_S	0.577	0.93
347_I	352_Y	0.577	0.93
43_L	50_T	0.576	0.93
515_D	521_C	0.576	0.93
546_E	558_A	0.575	0.93
118_W	121_N	0.575	0.93
399_A	403_L	0.575	0.93
502_T	533_A	0.575	0.93
72_V	77_L	0.574	0.93
464_N	473_A	0.574	0.93
469_L	477_V	0.572	0.93
60_G	68_I	0.572	0.93
23_G	29_H	0.572	0.93
217_N	221_N	0.571	0.93
531_E	534_E	0.571	0.93
434_Y	518_I	0.571	0.93
558_A	563_A	0.570	0.93
214_E	220_K	0.570	0.93
330_G	374_R	0.567	0.92
478_M	482_V	0.567	0.92
32_T	36_G	0.567	0.92
13_V	287_V	0.566	0.92
518_I	522_L	0.566	0.92
396_G	499_K	0.566	0.92
88_T	350_A	0.566	0.92
558_A	561_E	0.565	0.92
131_V	141_L	0.564	0.92
210_I	220_K	0.564	0.92
557_A	563_A	0.563	0.92
180_S	184_G	0.563	0.92
335_D	344_N	0.561	0.92
311_W	323_P	0.561	0.92
256_L	260_V	0.561	0.92
505_A	512_R	0.561	0.92
35_S	443_L	0.560	0.92
142_P	145_Y	0.559	0.92
24_D	81_R	0.557	0.92
395_V	492_L	0.557	0.92
365_Y	382_E	0.556	0.92
331_F	338_G	0.556	0.92
64_A	241_D	0.555	0.92
394_A	454_A	0.554	0.91
175_I	179_V	0.554	0.91
148_G	175_I	0.554	0.91
53_V	270_T	0.554	0.91
75_L	78_G	0.554	0.91
149_T	177_A	0.554	0.91
497_P	500_T	0.553	0.91
367_A	447_G	0.553	0.91
68_I	74_P	0.553	0.91
72_V	80_E	0.553	0.91
437_A	442_D	0.553	0.91
403_L	506_Q	0.552	0.91
400_Y	403_L	0.551	0.91
479_R	483_Q	0.551	0.91
543_R	549_E	0.550	0.91
131_V	140_W	0.550	0.91
312_P	321_A	0.549	0.91
114_F	118_W	0.549	0.91
423_V	460_Y	0.548	0.91
546_E	552_A	0.548	0.91
199_L	313_S	0.548	0.91
406_A	478_M	0.547	0.91
351_E	380_W	0.545	0.91
9_D	517_T	0.545	0.91
531_E	535_L	0.544	0.91
409_N	479_R	0.544	0.91
547_L	550_A	0.543	0.91
66_Q	81_R	0.543	0.91
108_V	112_R	0.542	0.91
95_A	514_S	0.542	0.91
194_H	239_D	0.541	0.91
426_E	453_L	0.541	0.91
401_R	461_I	0.539	0.90
400_Y	506_Q	0.539	0.90
402_A	485_V	0.538	0.90
425_T	527_A	0.537	0.90
62_P	181_T	0.536	0.90
543_R	559_S	0.535	0.90
51_V	283_D	0.533	0.90
382_E	386_R	0.533	0.90
218_N	301_R	0.532	0.90
56_T	82_H	0.530	0.90
438_L	518_I	0.530	0.90
545_T	550_A	0.530	0.90
349_A	352_Y	0.530	0.90
48_Q	439_N	0.530	0.90
428_A	487_A	0.530	0.90
459_E	462_Q	0.530	0.90
246_Y	256_L	0.530	0.90
121_N	316_A	0.529	0.90
425_T	524_A	0.528	0.89
114_F	267_V	0.528	0.89
32_T	35_S	0.528	0.89
333_N	336_G	0.526	0.89
158_R	162_C	0.526	0.89
545_T	562_D	0.526	0.89
456_F	459_E	0.526	0.89
399_A	506_Q	0.525	0.89
270_T	287_V	0.525	0.89
271_K	283_D	0.523	0.89
421_D	424_E	0.523	0.89
112_R	245_D	0.523	0.89
425_T	526_P	0.521	0.89
210_I	213_M	0.520	0.89
159_G	163_D	0.520	0.89
380_W	384_A	0.520	0.89
535_L	539_I	0.518	0.89
202_F	206_L	0.518	0.89
141_L	180_S	0.517	0.88
389_T	393_D	0.517	0.88
276_R	286_S	0.517	0.88
399_A	402_A	0.516	0.88
249_E	253_D	0.516	0.88
163_D	169_H	0.516	0.88
109_E	271_K	0.516	0.88
132_A	187_A	0.514	0.88
237_T	246_Y	0.514	0.88
486_K	508_G	0.511	0.88
223_P	312_P	0.511	0.88
525_P	530_G	0.511	0.88
427_I	430_A	0.511	0.88
301_R	328_A	0.511	0.88
275_E	281_E	0.510	0.88
357_F	383_F	0.509	0.88
108_V	245_D	0.509	0.88
80_E	87_D	0.509	0.88
544_V	553_A	0.508	0.88
129_I	192_R	0.508	0.88
398_F	454_A	0.508	0.88
62_P	142_P	0.508	0.88
483_Q	486_K	0.508	0.88
316_A	321_A	0.507	0.87
231_L	313_S	0.507	0.87
504_W	508_G	0.507	0.87
339_L	344_N	0.506	0.87
410_F	414_P	0.506	0.87
482_V	508_G	0.506	0.87
347_I	378_F	0.505	0.87
218_N	221_N	0.505	0.87
27_I	362_L	0.504	0.87
559_S	562_D	0.504	0.87
32_T	298_V	0.504	0.87
214_E	440_E	0.504	0.87
54_S	96_F	0.504	0.87
196_F	235_C	0.504	0.87
371_G	444_R	0.503	0.87
45_K	518_I	0.502	0.87
486_K	504_W	0.502	0.87
124_V	256_L	0.502	0.87
66_Q	77_L	0.501	0.87
267_V	315_L	0.501	0.87
543_R	551_L	0.501	0.87
25_L	92_F	0.500	0.87
240_L	255_V	0.500	0.87
65_V	137_A	0.500	0.87
305_Q	309_V	0.500	0.87

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1rqgA	2	0.8142	100	0.204	Contact Map
1gaxA	1	0.9507	100	0.332	Contact Map
1ffyA	1	0.8955	100	0.361	Contact Map
1ileA	1	0.7837	100	0.382	Contact Map
3kflA	1	0.7344	100	0.403	Contact Map
1wz2A	1	0.9231	100	0.412	Contact Map
3h99A	1	0.7692	100	0.413	Contact Map
3ziuA	1	0.7533	100	0.427	Contact Map
4qreA	1	0.7242	100	0.432	Contact Map
4arcA	1	0.7431	100	0.436	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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