Q9HSA2 - HALSA - GREMLIN Contacts

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Q9HSA2 - Zinc metalloproteinase homolog

UniProt:	Q9HSA2	Sequences: MLVHHVVFLALVAGTTLLFASLAALNVRYAERTVRERSAWLATHIGVDDPGELLAYHRLGTAVSQLRSVVLAGAVLGVLYTGAFGAAVAFVYDTVGSDVLAGVALLVGATVAMQVARVPFDAVETFGVESAFGFNEQSPALFARDALLSAGLAGVFVAVLGGAVLVAVAALPEWWFVAATGIVGVFLLATQVLVPRVVMPLFYDFDPVDEGGLRDAIEDVFDRAGFACEQVYVMNASSRSGHSNAFFTGFGATKRVVLFDTLIDQMGETELQAVLAHELAHWKNGHIWQTIGAATLQAGVVLFVASRLLDAGWLYGMFGVPEQPAAGLLLAGVWLQPLSRLTAPLQNRLWLANEREADAFAVDVMGGGEPLADALGALTSQNLGNPFPHPYYEAFHYQHPPVPERIRYLTAADSGAAAERSACRERNR	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	428 (401)
Sequences:	1241 (973)
Seq/√Len:	48.6

BACSU - YHFN
HALSA - Q9HSA2 Q9HS47

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
59_L	132_F	5.656	1.00
362_V	409_L	5.294	1.00
372_A	406_I	4.794	1.00
122_A	139_P	4.629	1.00
25_L	389_H	4.206	1.00
199_M	246_F	4.086	1.00
193_L	197_V	4.022	1.00
212_G	268_E	3.439	1.00
144_R	148_L	3.215	1.00
216_A	272_Q	3.152	1.00
46_G	49_D	3.026	1.00
125_T	137_Q	2.999	1.00
164_V	179_A	2.960	1.00
270_E	377_A	2.915	1.00
216_A	268_E	2.897	1.00
276_A	361_A	2.800	1.00
47_V	51_G	2.783	1.00
194_V	199_M	2.781	1.00
203_Y	235_N	2.706	1.00
199_M	205_F	2.706	1.00
211_G	214_R	2.638	1.00
286_H	356_E	2.585	1.00
206_D	209_D	2.539	1.00
140_A	144_R	2.454	1.00
184_G	295_T	2.437	1.00
163_A	182_I	2.397	1.00
194_V	246_F	2.390	1.00
359_A	408_Y	2.339	1.00
284_N	356_E	2.278	1.00
205_F	234_M	2.251	1.00
290_T	353_N	2.244	1.00
355_R	401_P	2.216	1.00
214_R	218_E	2.164	1.00
70_V	120_F	2.133	1.00
70_V	116_A	2.111	1.00
393_E	397_Y	2.107	1.00
270_E	373_D	2.077	1.00
289_Q	356_E	2.074	1.00
352_A	356_E	2.057	1.00
88_V	324_P	2.043	1.00
269_T	370_P	2.039	1.00
122_A	142_F	2.027	1.00
21_S	25_L	2.001	0.99
303_F	307_R	1.992	0.99
210_E	214_R	1.966	0.99
397_Y	401_P	1.957	0.99
179_A	302_L	1.938	0.99
145_D	239_R	1.936	0.99
103_V	107_V	1.924	0.99
39_A	42_A	1.914	0.99
74_A	116_A	1.902	0.99
30_A	57_H	1.897	0.99
221_F	228_C	1.893	0.99
49_D	380_S	1.844	0.99
368_G	409_L	1.839	0.99
224_A	360_F	1.811	0.99
95_V	100_L	1.784	0.99
51_G	55_A	1.781	0.99
385_N	388_P	1.773	0.99
147_L	151_G	1.767	0.99
175_W	344_P	1.753	0.99
91_V	108_G	1.752	0.99
246_F	255_R	1.744	0.99
393_E	401_P	1.739	0.99
246_F	257_V	1.732	0.98
186_F	190_T	1.724	0.98
130_S	135_N	1.718	0.98
139_P	142_F	1.717	0.98
130_S	136_E	1.714	0.98
236_A	240_S	1.706	0.98
139_P	143_A	1.704	0.98
289_Q	353_N	1.694	0.98
67_R	120_F	1.672	0.98
137_Q	141_L	1.657	0.98
372_A	410_T	1.609	0.98
393_E	404_E	1.606	0.98
353_N	356_E	1.603	0.97
235_N	238_S	1.586	0.97
233_V	263_I	1.582	0.97
123_V	127_G	1.579	0.97
52_E	123_V	1.551	0.97
177_V	181_G	1.518	0.97
111_V	115_V	1.515	0.96
265_Q	381_Q	1.511	0.96
59_L	128_V	1.511	0.96
160_L	182_I	1.502	0.96
392_Y	396_H	1.498	0.96
373_D	377_A	1.484	0.96
401_P	404_E	1.478	0.96
49_D	52_E	1.471	0.96
129_E	242_H	1.470	0.96
95_V	101_A	1.464	0.96
217_I	272_Q	1.459	0.96
66_L	69_V	1.455	0.96
171_L	178_A	1.452	0.95
27_V	61_T	1.437	0.95
205_F	255_R	1.430	0.95
16_T	69_V	1.402	0.95
136_E	241_G	1.399	0.94
129_E	240_S	1.392	0.94
77_G	81_T	1.391	0.94
70_V	74_A	1.371	0.94
243_S	265_Q	1.366	0.94
152_L	157_V	1.363	0.94
359_A	363_D	1.363	0.94
72_A	76_L	1.362	0.94
203_Y	234_M	1.350	0.93
134_F	242_H	1.348	0.93
146_A	149_S	1.346	0.93
22_L	395_F	1.345	0.93
234_M	246_F	1.332	0.93
91_V	104_A	1.331	0.93
182_I	186_F	1.310	0.92
212_G	215_D	1.299	0.92
205_F	246_F	1.297	0.92
14_G	18_L	1.288	0.92
40_W	410_T	1.280	0.91
367_G	370_P	1.278	0.91
400_P	405_R	1.275	0.91
98_D	169_A	1.270	0.91
56_Y	129_E	1.267	0.91
277_H	281_H	1.255	0.91
75_V	333_V	1.253	0.90
220_V	279_L	1.252	0.90
273_A	371_L	1.245	0.90
59_L	131_A	1.238	0.90
180_T	299_G	1.237	0.90
215_D	218_E	1.229	0.90
315_Y	327_G	1.219	0.89
90_F	108_G	1.218	0.89
285_G	288_W	1.218	0.89
187_L	190_T	1.212	0.89
208_V	233_V	1.200	0.88
88_V	92_Y	1.196	0.88
78_V	83_A	1.194	0.88
87_A	112_A	1.185	0.88
360_F	392_Y	1.183	0.88
266_M	377_A	1.180	0.88
45_I	386_P	1.178	0.87
78_V	116_A	1.176	0.87
218_E	231_V	1.168	0.87
121_D	146_A	1.168	0.87
152_L	197_V	1.166	0.87
146_A	150_A	1.164	0.87
131_A	204_D	1.160	0.87
88_V	326_A	1.158	0.87
143_A	147_L	1.150	0.86
41_L	402_V	1.143	0.86
31_E	58_R	1.142	0.86
355_R	408_Y	1.140	0.86
9_L	13_A	1.138	0.86
91_V	101_A	1.138	0.86
362_V	368_G	1.134	0.85
243_S	393_E	1.130	0.85
21_S	389_H	1.126	0.85
79_L	82_G	1.126	0.85
73_G	147_L	1.119	0.85
243_S	381_Q	1.119	0.85
94_T	97_S	1.119	0.85
184_G	291_I	1.113	0.84
145_D	260_D	1.113	0.84
385_N	389_H	1.108	0.84
209_D	214_R	1.107	0.84
63_V	67_R	1.101	0.84
52_E	136_E	1.093	0.83
23_A	61_T	1.084	0.83
389_H	393_E	1.083	0.83
18_L	395_F	1.082	0.83
107_V	158_A	1.082	0.83
277_H	354_E	1.081	0.83
145_D	244_N	1.080	0.82
252_A	401_P	1.078	0.82
162_G	166_V	1.074	0.82
13_A	17_L	1.062	0.81
234_M	259_F	1.060	0.81
388_P	397_Y	1.049	0.81
345_L	349_L	1.041	0.80
99_V	162_G	1.039	0.80
226_F	247_F	1.033	0.80
145_D	202_F	1.032	0.79
92_Y	101_A	1.027	0.79
99_V	155_V	1.026	0.79
251_G	255_R	1.017	0.78
126_F	138_S	1.015	0.78
237_S	260_D	1.014	0.78
187_L	191_Q	1.012	0.78
40_W	407_R	1.009	0.78
281_H	354_E	1.007	0.78
308_L	314_L	1.007	0.78
170_A	181_G	1.006	0.78
172_P	308_L	1.003	0.77
185_V	189_A	0.998	0.77
102_G	165_L	0.996	0.77
245_A	399_H	0.994	0.77
379_T	402_V	0.993	0.77
171_L	174_W	0.992	0.77
23_A	64_S	0.990	0.77
23_A	396_H	0.986	0.76
274_V	399_H	0.978	0.76
274_V	374_A	0.975	0.75
141_L	144_R	0.974	0.75
195_P	205_F	0.969	0.75
263_I	271_L	0.967	0.75
390_P	394_A	0.964	0.75
234_M	272_Q	0.964	0.75
258_L	263_I	0.960	0.74
181_G	185_V	0.958	0.74
375_L	402_V	0.956	0.74
60_G	124_E	0.955	0.74
134_F	239_R	0.952	0.74
195_P	248_T	0.949	0.73
16_T	20_A	0.947	0.73
103_V	158_A	0.945	0.73
76_L	360_F	0.944	0.73
176_F	282_W	0.943	0.73
126_F	135_N	0.937	0.72
105_L	339_S	0.936	0.72
182_I	246_F	0.934	0.72
399_H	405_R	0.928	0.72
127_G	130_S	0.928	0.72
297_Q	339_S	0.925	0.72
21_S	28_R	0.924	0.71
350_W	398_Q	0.924	0.71
26_N	385_N	0.921	0.71
20_A	65_Q	0.917	0.71
196_R	253_T	0.916	0.71
14_G	31_E	0.914	0.71
78_V	109_A	0.914	0.71
73_G	304_V	0.911	0.70
200_P	255_R	0.908	0.70
239_R	259_F	0.908	0.70
17_L	321_P	0.906	0.70
48_D	52_E	0.904	0.70
304_V	345_L	0.893	0.69
202_F	260_D	0.892	0.69
268_E	272_Q	0.887	0.68
167_A	182_I	0.883	0.68
259_F	262_L	0.882	0.68
26_N	389_H	0.881	0.68
244_N	261_T	0.881	0.68
126_F	240_S	0.879	0.68
157_V	161_G	0.877	0.67
218_E	222_D	0.874	0.67
235_N	239_R	0.868	0.67
14_G	345_L	0.861	0.66
145_D	203_Y	0.861	0.66
392_Y	397_Y	0.848	0.65
43_T	163_A	0.847	0.65
177_V	299_G	0.847	0.65
332_G	335_L	0.847	0.65
371_L	375_L	0.845	0.64
50_P	383_L	0.842	0.64
194_V	257_V	0.840	0.64
184_G	299_G	0.839	0.64
24_A	28_R	0.839	0.64
19_F	396_H	0.837	0.64
240_S	275_L	0.836	0.64
211_G	215_D	0.832	0.63
23_A	283_K	0.828	0.63
213_L	217_I	0.826	0.63
257_V	261_T	0.823	0.62
52_E	204_D	0.820	0.62
236_A	239_R	0.819	0.62
358_D	405_R	0.818	0.62
18_L	27_V	0.818	0.62
122_A	143_A	0.817	0.62
234_M	257_V	0.816	0.62
214_R	287_I	0.813	0.61
379_T	386_P	0.812	0.61
199_M	248_T	0.810	0.61
85_G	404_E	0.808	0.61
293_A	349_L	0.804	0.61
253_T	344_P	0.803	0.61
163_A	186_F	0.802	0.60
145_D	261_T	0.802	0.60
315_Y	330_L	0.800	0.60
29_Y	32_R	0.798	0.60
354_E	357_A	0.790	0.59
203_Y	246_F	0.790	0.59
202_F	239_R	0.789	0.59
111_V	296_L	0.787	0.59
247_F	261_T	0.787	0.59
327_G	330_L	0.785	0.59
393_E	409_L	0.782	0.58
232_Y	255_R	0.782	0.58
138_S	141_L	0.782	0.58
176_F	303_F	0.780	0.58
54_L	58_R	0.778	0.58
107_V	154_G	0.776	0.58
199_M	234_M	0.774	0.58
304_V	331_A	0.774	0.58
375_L	382_N	0.773	0.58
228_C	282_W	0.773	0.58
134_F	202_F	0.771	0.57
187_L	360_F	0.768	0.57
273_A	375_L	0.765	0.57
45_I	197_V	0.765	0.57
123_V	254_K	0.764	0.57
263_I	268_E	0.763	0.57
13_A	18_L	0.762	0.57
107_V	150_A	0.762	0.57
107_V	181_G	0.761	0.56
112_A	186_F	0.761	0.56
70_V	209_D	0.760	0.56
132_F	221_F	0.758	0.56
355_R	404_E	0.758	0.56
244_N	382_N	0.757	0.56
389_H	394_A	0.755	0.56
145_D	237_S	0.751	0.55
319_G	330_L	0.748	0.55
176_F	388_P	0.745	0.55
50_P	54_L	0.744	0.55
22_L	25_L	0.743	0.55
221_F	279_L	0.741	0.54
299_G	302_L	0.741	0.54
155_V	407_R	0.741	0.54
97_S	100_L	0.736	0.54
154_G	158_A	0.732	0.54
46_G	51_G	0.726	0.53
243_S	282_W	0.724	0.53
152_L	184_G	0.724	0.53
392_Y	404_E	0.723	0.53
213_L	263_I	0.723	0.53
7_V	335_L	0.723	0.53
216_A	219_D	0.720	0.52
10_A	13_A	0.720	0.52
128_V	270_E	0.720	0.52
203_Y	239_R	0.720	0.52
302_L	312_G	0.717	0.52
406_I	410_T	0.717	0.52
128_V	274_V	0.716	0.52
8_F	184_G	0.715	0.52
258_L	271_L	0.714	0.52
73_G	115_V	0.713	0.52
282_W	285_G	0.711	0.51
174_W	177_V	0.710	0.51
23_A	26_N	0.709	0.51
50_P	386_P	0.709	0.51
270_E	383_L	0.709	0.51
114_Q	146_A	0.707	0.51
140_A	155_V	0.707	0.51
218_E	228_C	0.707	0.51
320_V	330_L	0.706	0.51
397_Y	404_E	0.703	0.51
129_E	134_F	0.703	0.51
245_A	260_D	0.699	0.50
245_A	274_V	0.698	0.50
342_T	346_Q	0.695	0.50
254_K	282_W	0.695	0.50
103_V	301_V	0.694	0.50
259_F	375_L	0.693	0.50
127_G	131_A	0.690	0.49
183_V	302_L	0.688	0.49
239_R	375_L	0.688	0.49
93_D	108_G	0.687	0.49
155_V	159_V	0.687	0.49
252_A	255_R	0.686	0.49
242_H	393_E	0.686	0.49
256_V	360_F	0.683	0.49
267_G	377_A	0.681	0.48
166_V	170_A	0.681	0.48
312_G	316_G	0.680	0.48
304_V	334_W	0.679	0.48
217_I	258_L	0.677	0.48
354_E	399_H	0.676	0.48
149_S	288_W	0.673	0.48
156_F	349_L	0.672	0.47
134_F	259_F	0.671	0.47
247_F	282_W	0.670	0.47
226_F	279_L	0.669	0.47
335_L	339_S	0.668	0.47
129_E	135_N	0.668	0.47
111_V	150_A	0.668	0.47
92_Y	97_S	0.662	0.46
254_K	392_Y	0.661	0.46
314_L	318_F	0.660	0.46
403_P	407_R	0.660	0.46
243_S	404_E	0.659	0.46
45_I	256_V	0.659	0.46
290_T	294_A	0.657	0.46
145_D	257_V	0.656	0.46
354_E	358_D	0.652	0.45
19_F	189_A	0.652	0.45
213_L	272_Q	0.652	0.45
343_A	350_W	0.649	0.45
347_N	383_L	0.649	0.45
375_L	409_L	0.648	0.45
82_G	326_A	0.648	0.45
145_D	236_A	0.647	0.45
175_W	297_Q	0.646	0.45
12_V	72_A	0.644	0.45
11_L	18_L	0.643	0.45
274_V	385_N	0.643	0.45
247_F	262_L	0.642	0.44
66_L	345_L	0.641	0.44
124_E	309_L	0.640	0.44
7_V	14_G	0.639	0.44
288_W	292_G	0.638	0.44
228_C	236_A	0.636	0.44
164_V	212_G	0.634	0.44
85_G	320_V	0.634	0.44
238_S	377_A	0.634	0.44
277_H	399_H	0.633	0.44
216_A	269_T	0.633	0.44
60_G	136_E	0.633	0.44
244_N	278_E	0.631	0.43
377_A	386_P	0.630	0.43
357_A	405_R	0.629	0.43
51_G	151_G	0.629	0.43
281_H	358_D	0.629	0.43
164_V	302_L	0.628	0.43
402_V	406_I	0.627	0.43
182_I	404_E	0.626	0.43
240_S	247_F	0.625	0.43
17_L	36_E	0.625	0.43
30_A	53_L	0.624	0.43
266_M	381_Q	0.623	0.43
199_M	203_Y	0.623	0.43
195_P	253_T	0.622	0.42
155_V	171_L	0.622	0.42
266_M	274_V	0.622	0.42
66_L	93_D	0.622	0.42
263_I	279_L	0.621	0.42
284_N	288_W	0.621	0.42
50_P	208_V	0.620	0.42
211_G	263_I	0.620	0.42
133_G	239_R	0.619	0.42
220_V	256_V	0.619	0.42
349_L	352_A	0.619	0.42
148_L	202_F	0.619	0.42
43_T	47_V	0.618	0.42
247_F	259_F	0.618	0.42
52_E	63_V	0.617	0.42
9_L	28_R	0.616	0.42
335_L	338_L	0.615	0.42
103_V	165_L	0.614	0.42
136_E	231_V	0.612	0.41
358_D	400_P	0.612	0.41
207_P	378_L	0.607	0.41
145_D	148_L	0.604	0.41
114_Q	150_A	0.604	0.41
256_V	284_N	0.604	0.41
126_F	129_E	0.603	0.41
376_G	406_I	0.602	0.40
63_V	128_V	0.602	0.40
141_L	148_L	0.601	0.40
128_V	294_A	0.601	0.40
217_I	229_E	0.598	0.40
246_F	261_T	0.595	0.40
10_A	28_R	0.594	0.40
109_A	276_A	0.594	0.40
290_T	350_W	0.592	0.40
244_N	361_A	0.592	0.40
26_N	392_Y	0.591	0.39
159_V	162_G	0.591	0.39
203_Y	236_A	0.591	0.39
244_N	399_H	0.590	0.39
194_V	203_Y	0.590	0.39
135_N	138_S	0.589	0.39
16_T	72_A	0.589	0.39
111_V	114_Q	0.587	0.39
37_R	47_V	0.587	0.39
378_L	383_L	0.586	0.39
286_H	353_N	0.585	0.39
174_W	185_V	0.585	0.39
164_V	327_G	0.585	0.39
40_W	406_I	0.584	0.39
307_R	314_L	0.582	0.39
245_A	262_L	0.582	0.39
312_G	323_Q	0.581	0.38
121_D	320_V	0.581	0.38
102_G	337_P	0.581	0.38
124_E	204_D	0.580	0.38
110_T	161_G	0.579	0.38
239_R	244_N	0.579	0.38
255_R	261_T	0.578	0.38
175_W	195_P	0.577	0.38
248_T	287_I	0.577	0.38
17_L	67_R	0.576	0.38
289_Q	349_L	0.576	0.38
244_N	378_L	0.575	0.38
167_A	176_F	0.575	0.38
103_V	141_L	0.575	0.38
17_L	369_E	0.575	0.38
184_G	193_L	0.575	0.38
205_F	239_R	0.574	0.38
62_A	69_V	0.573	0.38
7_V	293_A	0.573	0.38
118_V	309_L	0.573	0.38
13_A	76_L	0.571	0.38
115_V	360_F	0.569	0.37
40_W	131_A	0.569	0.37
110_T	296_L	0.568	0.37
252_A	318_F	0.568	0.37
124_E	264_D	0.568	0.37
219_D	300_V	0.567	0.37
296_L	300_V	0.567	0.37
135_N	145_D	0.567	0.37
184_G	189_A	0.565	0.37
321_P	349_L	0.565	0.37
119_P	200_P	0.565	0.37
285_G	360_F	0.565	0.37
49_D	383_L	0.562	0.37
278_E	399_H	0.561	0.37
96_G	108_G	0.561	0.37
173_E	310_D	0.560	0.36
279_L	282_W	0.560	0.36
391_Y	406_I	0.560	0.36
388_P	401_P	0.560	0.36
25_L	385_N	0.560	0.36
355_R	398_Q	0.558	0.36
330_L	337_P	0.557	0.36
221_F	227_A	0.556	0.36
153_A	183_V	0.556	0.36
222_D	360_F	0.555	0.36
140_A	167_A	0.555	0.36
240_S	286_H	0.554	0.36
132_F	181_G	0.553	0.36
243_S	382_N	0.551	0.36
241_G	271_L	0.551	0.36
236_A	259_F	0.550	0.36
48_D	89_A	0.548	0.35
133_G	261_T	0.548	0.35
125_T	180_T	0.546	0.35
26_N	128_V	0.545	0.35
60_G	370_P	0.545	0.35
199_M	339_S	0.545	0.35
213_L	268_E	0.544	0.35
236_A	257_V	0.544	0.35
70_V	96_G	0.543	0.35
79_L	83_A	0.543	0.35
104_A	111_V	0.542	0.35
72_A	80_Y	0.542	0.35
63_V	70_V	0.541	0.35
11_L	15_T	0.540	0.35
8_F	30_A	0.540	0.35
175_W	221_F	0.539	0.35
24_A	349_L	0.539	0.35
24_A	65_Q	0.537	0.34
219_D	222_D	0.537	0.34
242_H	361_A	0.536	0.34
141_L	239_R	0.536	0.34
91_V	99_V	0.536	0.34
205_F	263_I	0.534	0.34
378_L	382_N	0.534	0.34
377_A	381_Q	0.534	0.34
239_R	261_T	0.533	0.34
7_V	21_S	0.533	0.34
292_G	321_P	0.531	0.34
53_L	190_T	0.531	0.34
219_D	363_D	0.531	0.34
175_W	305_A	0.530	0.34
8_F	11_L	0.530	0.34
86_A	90_F	0.528	0.34
10_A	99_V	0.528	0.34
237_S	245_A	0.528	0.34
111_V	250_F	0.527	0.33
36_E	89_A	0.527	0.33
286_H	360_F	0.526	0.33
200_P	260_D	0.526	0.33
50_P	385_N	0.526	0.33
225_G	274_V	0.525	0.33
305_A	331_A	0.525	0.33
38_S	41_L	0.524	0.33
181_G	264_D	0.523	0.33
197_V	294_A	0.522	0.33
300_V	373_D	0.521	0.33
315_Y	320_V	0.521	0.33
168_V	325_A	0.521	0.33
31_E	69_V	0.520	0.33
142_F	360_F	0.520	0.33
22_L	392_Y	0.520	0.33
202_F	236_A	0.519	0.33
76_L	80_Y	0.519	0.33
89_A	121_D	0.518	0.33
374_A	381_Q	0.516	0.32
15_T	26_N	0.516	0.32
18_L	349_L	0.515	0.32
221_F	256_V	0.514	0.32
168_V	175_W	0.513	0.32
307_R	394_A	0.513	0.32
224_A	279_L	0.513	0.32
203_Y	347_N	0.512	0.32
340_R	344_P	0.512	0.32
165_L	304_V	0.512	0.32
135_N	240_S	0.511	0.32
119_P	205_F	0.511	0.32
271_L	343_A	0.510	0.32
200_P	261_T	0.509	0.32
236_A	371_L	0.508	0.32
156_F	189_A	0.508	0.32
66_L	120_F	0.507	0.32
369_E	410_T	0.507	0.32
76_L	90_F	0.506	0.32
183_V	298_A	0.505	0.31
28_R	115_V	0.505	0.31
284_N	360_F	0.504	0.31
239_R	246_F	0.504	0.31
195_P	257_V	0.503	0.31
54_L	385_N	0.502	0.31
176_F	344_P	0.501	0.31
206_D	233_V	0.500	0.31

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4aw6A	2	0.9556	100	0.195	Contact Map
4il3A	1	0.9533	100	0.198	Contact Map
3c37A	1	0.4743	100	0.721	Contact Map
3cqbA	4	0.2313	99.8	0.829	Contact Map
4qhjA	2	0.229	97.4	0.929	Contact Map
4jiuA	1	0.236	95.9	0.94	Contact Map
3dteA	2	0.3551	95.3	0.943	Contact Map
4jixA	2	0.2523	94.3	0.946	Contact Map
2kw0A	1	0.1636	36.1	0.969	Contact Map
4o66A	2	0.1636	35.8	0.969	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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