Q9HSA1 - HALSA - GREMLIN Contacts

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Q9HSA1 - Phosphoenolpyruvate synthase

UniProt:	Q9HSA1	Sequences: MAVRWLEDVRADDIDSVGGKGASLGELTDAGLPVPPGFVVTAGTYRTFIEEAGIDQELFDAVGVDAEDSDALADAAARASDLILNTDFPASLREDILSSYDALDDGAAFVAVRSSATAEDLPDASFAGQQETFLNITREALLDHVKRCWASLFTERAIYYRQEQGFDHDRVNIAVVVQRMVDAEKSGVLFTSHPSTGAHEAIVEAAWGLGEAVVSGAVSPDNYVVDRDTDTVEEATVADKKVMHVKDDDTGETVSRDVPDRKRTQRVLDDGEISDLVTIGERVEAHYDAPQDVEWAIVDGDVYMLQSRPITTIEDDTDGAVANTDGGGGDAVVTGLGASPGVASGPARVVTSLDELDKIGEGDIIATEMTTPDMVPAMKRAAGIVTDEGGMTSHAAIVSRELGCPAVVGATDATTTLCDDQAVTLDGDRGVVRDGREETTTEHDPIEDARPTTPVKPMTATEVKVNVSIPEAAERAAATGADGVGLLRMEHMILSTNKTPKRYIDDHGEDAYVQELVDGIRGVAEEFYPRPVRVRTLDAPTDEFRQLEGGNDEPHEHNPMLGYRGVRRSLDRPDVFKHELSAFRRLYEMGYDNVEVMFPLVNDAQDVARARDLMADAGIDVEKRSWGVMIETPAAALAIEEIAQEGVDFASFGTNDLTQYTLAVDRNNGSVADRFDELHPSVLTLIERTIDACREHDVATSICGQAGSKPEMVDFLVETGVSSISANIDAVRDVQHEVKRVEQRLLLESARE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	752 (714)
Sequences:	2726 (1449)
Seq/√Len:	54.2

ECOLI - PPSA
HALSA - Q9HSA1
SULSO - Q97ZL2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
347_A	417_L	6.992	1.00
383_G	425_L	4.956	1.00
648_D	695_E	4.678	1.00
346_P	361_E	4.380	1.00
684_T	692_A	4.108	1.00
288_D	292_D	3.999	1.00
687_E	691_D	3.788	1.00
300_G	457_P	3.780	1.00
702_I	716_L	3.635	1.00
525_E	589_M	3.547	1.00
362_G	382_A	3.542	1.00
126_F	132_T	3.478	1.00
299_D	302_V	3.402	1.00
598_F	614_M	3.320	1.00
536_T	598_F	3.257	1.00
205_A	267_V	3.210	1.00
502_R	515_E	3.199	1.00
105_D	114_S	3.165	1.00
563_Y	571_D	3.153	1.00
117_T	121_L	3.067	1.00
632_T	660_Y	3.065	1.00
506_D	510_D	2.992	1.00
640_E	692_A	2.983	1.00
116_A	121_L	2.978	1.00
477_A	530_R	2.947	1.00
118_A	121_L	2.900	1.00
321_V	424_T	2.889	1.00
183_A	270_D	2.842	1.00
212_A	255_S	2.836	1.00
461_T	717_V	2.772	1.00
91_S	171_V	2.768	1.00
105_D	109_F	2.744	1.00
510_D	514_Q	2.742	1.00
110_V	114_S	2.727	1.00
109_F	114_S	2.657	1.00
686_I	719_T	2.653	1.00
417_L	434_D	2.621	1.00
111_A	114_S	2.612	1.00
352_S	419_D	2.609	1.00
611_R	615_A	2.599	1.00
690_I	700_T	2.584	1.00
422_A	436_R	2.578	1.00
105_D	110_V	2.529	1.00
620_D	623_K	2.488	1.00
569_S	576_F	2.439	1.00
677_E	709_K	2.439	1.00
510_D	577_K	2.389	1.00
527_F	532_V	2.379	1.00
330_D	434_D	2.369	1.00
110_V	116_A	2.341	1.00
74_D	77_A	2.329	1.00
115_S	121_L	2.319	1.00
167_D	170_R	2.313	1.00
105_D	111_A	2.275	1.00
347_A	423_V	2.229	1.00
10_R	29_D	2.214	1.00
583_F	596_V	2.194	1.00
577_K	616_D	2.185	1.00
331_A	433_R	2.184	1.00
641_E	684_T	2.175	1.00
586_L	594_V	2.161	1.00
108_A	120_D	2.147	1.00
73_A	269_D	2.140	1.00
615_A	626_W	2.094	1.00
162_Q	168_H	2.092	1.00
459_T	482_D	2.092	1.00
576_F	610_A	2.090	1.00
684_T	688_R	2.074	1.00
462_E	482_D	2.029	1.00
456_K	459_T	2.025	1.00
630_I	689_T	2.012	1.00
47_T	51_E	2.007	1.00
602_N	632_T	1.997	1.00
116_A	120_D	1.982	1.00
115_S	118_A	1.970	1.00
595_E	625_S	1.968	1.00
364_I	383_G	1.963	1.00
107_A	111_A	1.952	1.00
460_A	717_V	1.936	1.00
347_A	434_D	1.930	1.00
304_M	458_M	1.929	1.00
334_T	431_V	1.922	1.00
364_I	423_V	1.922	1.00
234_E	238_A	1.913	1.00
108_A	114_S	1.896	0.99
474_E	478_A	1.896	0.99
385_V	425_L	1.886	0.99
110_V	115_S	1.885	0.99
523_V	532_V	1.884	0.99
680_P	718_E	1.882	0.99
637_L	685_L	1.874	0.99
577_K	613_L	1.871	0.99
348_R	356_L	1.867	0.99
107_A	110_V	1.866	0.99
522_G	526_E	1.862	0.99
15_D	91_S	1.857	0.99
634_A	681_S	1.857	0.99
333_V	410_A	1.844	0.99
714_D	718_E	1.828	0.99
689_T	700_T	1.820	0.99
464_K	595_E	1.813	0.99
661_T	682_V	1.810	0.99
206_A	213_V	1.802	0.99
684_T	687_E	1.785	0.99
125_S	131_E	1.778	0.99
347_A	366_A	1.778	0.99
355_E	358_K	1.776	0.99
346_P	422_A	1.772	0.99
333_V	432_V	1.761	0.99
232_V	238_A	1.761	0.99
110_V	121_L	1.757	0.99
58_L	79_A	1.747	0.99
693_C	698_V	1.740	0.99
117_T	120_D	1.730	0.99
475_R	478_A	1.728	0.99
233_E	238_A	1.722	0.99
615_A	619_I	1.716	0.99
584_R	618_G	1.715	0.99
477_A	526_E	1.711	0.99
518_D	522_G	1.709	0.99
618_G	626_W	1.704	0.99
288_D	447_E	1.704	0.99
36_P	179_R	1.701	0.99
577_K	617_A	1.683	0.99
109_F	112_V	1.678	0.99
521_R	525_E	1.678	0.99
201_A	251_G	1.674	0.99
533_R	699_A	1.673	0.99
505_D	508_G	1.662	0.99
612_D	616_D	1.660	0.99
107_A	114_S	1.657	0.99
106_G	110_V	1.651	0.99
71_A	75_A	1.638	0.99
661_T	685_L	1.623	0.98
484_V	527_F	1.619	0.98
687_E	719_T	1.618	0.98
686_I	716_L	1.618	0.98
336_L	391_M	1.613	0.98
473_A	527_F	1.610	0.98
299_D	303_Y	1.602	0.98
205_A	229_T	1.595	0.98
193_H	200_E	1.591	0.98
92_L	171_V	1.586	0.98
232_V	235_A	1.585	0.98
641_E	644_Q	1.584	0.98
580_L	614_M	1.581	0.98
351_T	376_P	1.581	0.98
225_V	228_D	1.575	0.98
301_D	458_M	1.567	0.98
605_Q	608_A	1.563	0.98
415_T	434_D	1.559	0.98
55_D	58_L	1.555	0.98
677_E	711_E	1.553	0.98
638_A	641_E	1.552	0.98
16_S	41_T	1.552	0.98
456_K	735_Q	1.546	0.98
611_R	648_D	1.541	0.98
50_E	55_D	1.540	0.98
536_T	583_F	1.532	0.98
106_G	109_F	1.526	0.98
62_V	145_V	1.524	0.98
16_S	43_G	1.518	0.98
352_S	356_L	1.518	0.98
617_A	620_D	1.498	0.97
115_S	120_D	1.495	0.97
620_D	624_R	1.492	0.97
521_R	589_M	1.484	0.97
694_R	722_S	1.483	0.97
458_M	742_E	1.476	0.97
261_R	280_G	1.471	0.97
368_E	387_D	1.460	0.97
105_D	121_L	1.455	0.97
637_L	684_T	1.454	0.97
473_A	523_V	1.452	0.97
110_V	113_R	1.445	0.97
616_D	620_D	1.444	0.97
191_T	293_V	1.444	0.97
585_R	621_V	1.436	0.97
108_A	111_A	1.430	0.96
230_D	233_E	1.418	0.96
189_L	237_V	1.418	0.96
473_A	532_V	1.408	0.96
146_K	150_A	1.408	0.96
234_E	237_V	1.406	0.96
524_A	594_V	1.402	0.96
604_A	638_A	1.399	0.96
581_S	585_R	1.397	0.96
687_E	718_E	1.396	0.96
283_V	304_M	1.392	0.96
322_A	438_E	1.389	0.96
9_V	13_D	1.383	0.96
502_R	511_A	1.381	0.96
205_A	225_V	1.381	0.96
378_M	384_I	1.380	0.96
605_Q	679_H	1.379	0.96
105_D	112_V	1.379	0.96
159_Y	163_E	1.379	0.96
344_S	436_R	1.379	0.96
259_P	302_V	1.377	0.96
105_D	108_A	1.376	0.96
517_V	585_R	1.374	0.96
296_A	305_L	1.368	0.95
93_R	97_L	1.358	0.95
484_V	523_V	1.353	0.95
298_V	306_Q	1.347	0.95
608_A	612_D	1.344	0.95
354_D	376_P	1.342	0.95
236_T	239_D	1.340	0.95
167_D	171_V	1.340	0.95
81_D	85_N	1.339	0.95
580_L	584_R	1.338	0.95
686_I	689_T	1.337	0.95
322_A	440_T	1.330	0.95
110_V	117_T	1.320	0.94
418_C	421_Q	1.316	0.94
118_A	122_P	1.307	0.94
153_F	158_I	1.299	0.94
205_A	223_Y	1.295	0.94
91_S	170_R	1.293	0.94
507_H	510_D	1.290	0.94
619_I	622_E	1.290	0.94
52_A	86_T	1.286	0.94
57_E	60_D	1.285	0.94
112_V	115_S	1.284	0.94
106_G	111_A	1.281	0.93
348_R	363_D	1.281	0.93
463_V	724_I	1.279	0.93
59_F	142_L	1.278	0.93
510_D	585_R	1.272	0.93
356_L	361_E	1.268	0.93
566_V	610_A	1.268	0.93
62_V	142_L	1.266	0.93
139_E	143_D	1.265	0.93
105_D	116_A	1.263	0.93
145_V	175_V	1.262	0.93
90_A	93_R	1.261	0.93
204_E	391_M	1.261	0.93
10_R	13_D	1.255	0.93
106_G	114_S	1.252	0.93
630_I	636_A	1.242	0.92
259_P	262_K	1.241	0.92
111_A	117_T	1.240	0.92
678_L	716_L	1.239	0.92
235_A	238_A	1.235	0.92
111_A	115_S	1.233	0.92
159_Y	375_V	1.228	0.92
221_D	225_V	1.228	0.92
272_E	297_I	1.227	0.92
300_G	458_M	1.227	0.92
602_N	664_V	1.226	0.92
644_Q	696_H	1.224	0.92
584_R	596_V	1.218	0.92
621_V	624_R	1.217	0.92
604_A	608_A	1.214	0.91
717_V	742_E	1.214	0.91
607_V	647_V	1.213	0.91
534_V	583_F	1.210	0.91
468_S	487_L	1.208	0.91
375_V	402_L	1.202	0.91
688_R	692_A	1.201	0.91
477_A	527_F	1.195	0.91
615_A	620_D	1.195	0.91
47_T	50_E	1.193	0.91
111_A	116_A	1.191	0.91
305_L	743_Q	1.190	0.91
602_N	662_L	1.189	0.91
116_A	119_E	1.189	0.91
105_D	117_T	1.188	0.91
475_R	729_D	1.185	0.90
614_M	626_W	1.184	0.90
105_D	113_R	1.174	0.90
613_L	616_D	1.156	0.89
660_Y	676_D	1.151	0.89
672_A	677_E	1.149	0.89
113_R	116_A	1.149	0.89
683_L	715_F	1.144	0.89
603_D	638_A	1.143	0.89
358_K	419_D	1.142	0.89
364_I	425_L	1.142	0.89
641_E	680_P	1.137	0.89
124_A	129_Q	1.136	0.89
105_D	115_S	1.136	0.89
54_I	58_L	1.130	0.88
314_E	318_D	1.129	0.88
46_R	55_D	1.128	0.88
550_G	553_E	1.128	0.88
339_S	397_I	1.127	0.88
670_S	673_D	1.127	0.88
192_S	199_H	1.126	0.88
465_V	476_A	1.126	0.88
640_E	695_E	1.115	0.88
344_S	439_T	1.115	0.88
110_V	118_A	1.114	0.88
291_Q	294_E	1.113	0.87
542_D	667_N	1.112	0.87
57_E	61_A	1.111	0.87
332_V	417_L	1.106	0.87
417_L	423_V	1.104	0.87
327_G	437_E	1.104	0.87
109_F	121_L	1.101	0.87
691_D	719_T	1.101	0.87
107_A	115_S	1.097	0.87
585_R	588_E	1.091	0.86
638_A	692_A	1.091	0.86
482_D	530_R	1.088	0.86
46_R	172_N	1.086	0.86
109_F	116_A	1.084	0.86
111_A	121_L	1.082	0.86
114_S	117_T	1.082	0.86
114_S	120_D	1.080	0.86
110_V	120_D	1.077	0.86
131_E	139_E	1.077	0.86
426_D	431_V	1.076	0.86
421_Q	434_D	1.075	0.86
337_G	391_M	1.075	0.86
581_S	624_R	1.075	0.86
331_A	431_V	1.071	0.85
28_T	36_P	1.067	0.85
232_V	237_V	1.065	0.85
570_L	609_R	1.064	0.85
520_I	596_V	1.062	0.85
463_V	738_V	1.061	0.85
186_S	213_V	1.059	0.85
262_K	265_Q	1.059	0.85
639_I	689_T	1.057	0.85
618_G	622_E	1.056	0.85
321_V	439_T	1.056	0.85
191_T	280_G	1.055	0.85
94_E	98_S	1.051	0.84
501_K	575_V	1.051	0.84
353_L	363_D	1.046	0.84
7_E	36_P	1.044	0.84
109_F	113_R	1.043	0.84
107_A	112_V	1.042	0.84
226_D	268_L	1.040	0.84
690_I	721_V	1.038	0.84
604_A	644_Q	1.035	0.83
534_V	594_V	1.034	0.83
155_E	159_Y	1.033	0.83
678_L	709_K	1.032	0.83
108_A	117_T	1.030	0.83
25_G	39_V	1.030	0.83
417_L	421_Q	1.030	0.83
715_F	719_T	1.027	0.83
233_E	237_V	1.026	0.83
223_Y	267_V	1.026	0.83
368_E	388_E	1.023	0.83
643_A	698_V	1.019	0.82
461_T	742_E	1.019	0.82
569_S	610_A	1.016	0.82
90_A	94_E	1.015	0.82
615_A	648_D	1.014	0.82
330_D	415_T	1.010	0.82
105_D	118_A	1.008	0.82
92_L	154_T	1.007	0.82
204_E	219_S	1.006	0.82
598_F	610_A	1.002	0.81
106_G	112_V	1.001	0.81
471_E	495_S	0.997	0.81
114_S	121_L	0.996	0.81
39_V	174_A	0.994	0.81
22_A	26_E	0.992	0.81
465_V	731_V	0.992	0.81
231_T	234_E	0.991	0.81
611_R	695_E	0.983	0.80
412_D	416_T	0.975	0.79
199_H	251_G	0.973	0.79
185_K	207_W	0.972	0.79
108_A	112_V	0.968	0.79
604_A	641_E	0.967	0.79
224_V	227_R	0.960	0.78
633_P	663_A	0.960	0.78
680_P	683_L	0.960	0.78
233_E	236_T	0.959	0.78
233_E	268_L	0.959	0.78
91_S	167_D	0.957	0.78
576_F	613_L	0.956	0.78
678_L	711_E	0.954	0.78
385_V	432_V	0.953	0.78
185_K	268_L	0.951	0.78
514_Q	581_S	0.946	0.77
632_T	664_V	0.942	0.77
226_D	234_E	0.940	0.77
361_E	380_R	0.939	0.77
352_S	355_E	0.939	0.77
109_F	115_S	0.937	0.77
548_E	551_N	0.934	0.76
163_E	375_V	0.933	0.76
226_D	230_D	0.933	0.76
159_Y	376_P	0.932	0.76
232_V	236_T	0.929	0.76
536_T	596_V	0.926	0.76
299_D	305_L	0.926	0.76
109_F	117_T	0.926	0.76
226_D	229_T	0.926	0.76
112_V	117_T	0.925	0.76
332_V	415_T	0.923	0.76
43_G	47_T	0.923	0.76
692_A	696_H	0.922	0.76
237_V	266_R	0.919	0.75
610_A	613_L	0.913	0.75
321_V	326_G	0.913	0.75
117_T	122_P	0.912	0.75
641_E	692_A	0.911	0.75
7_E	70_D	0.910	0.75
11_A	14_I	0.909	0.75
108_A	116_A	0.908	0.74
634_A	679_H	0.907	0.74
473_A	477_A	0.906	0.74
143_D	146_K	0.904	0.74
609_R	612_D	0.903	0.74
230_D	234_E	0.903	0.74
487_L	523_V	0.902	0.74
459_T	735_Q	0.902	0.74
477_A	529_P	0.898	0.74
379_K	402_L	0.895	0.73
680_P	711_E	0.893	0.73
660_Y	664_V	0.892	0.73
373_D	501_K	0.890	0.73
204_E	220_P	0.886	0.73
235_A	239_D	0.885	0.73
660_Y	663_A	0.884	0.72
226_D	233_E	0.882	0.72
509_E	512_Y	0.882	0.72
206_A	212_A	0.881	0.72
460_A	722_S	0.878	0.72
639_I	650_A	0.876	0.72
329_G	433_R	0.875	0.72
636_A	689_T	0.875	0.72
650_A	693_C	0.875	0.72
65_D	68_D	0.873	0.71
308_R	311_T	0.872	0.71
638_A	684_T	0.871	0.71
256_R	297_I	0.866	0.71
97_L	101_D	0.865	0.71
576_F	598_F	0.865	0.71
104_D	108_A	0.862	0.71
652_F	689_T	0.861	0.70
482_D	735_Q	0.861	0.70
494_L	670_S	0.860	0.70
194_P	202_I	0.860	0.70
68_D	71_A	0.859	0.70
509_E	513_V	0.859	0.70
9_V	12_D	0.857	0.70
385_V	423_V	0.856	0.70
333_V	417_L	0.855	0.70
54_I	146_K	0.854	0.70
413_A	417_L	0.851	0.70
154_T	158_I	0.850	0.69
61_A	78_R	0.849	0.69
636_A	685_L	0.848	0.69
346_P	356_L	0.847	0.69
470_P	522_G	0.844	0.69
211_E	214_V	0.844	0.69
376_P	405_P	0.842	0.69
625_S	699_A	0.840	0.69
405_P	433_R	0.839	0.68
239_D	253_T	0.839	0.68
709_K	713_V	0.838	0.68
49_I	83_I	0.835	0.68
119_E	122_P	0.834	0.68
200_E	224_V	0.833	0.68
601_V	632_T	0.832	0.68
371_T	494_L	0.832	0.68
291_Q	307_S	0.831	0.68
87_D	93_R	0.828	0.67
82_L	85_N	0.827	0.67
611_R	626_W	0.827	0.67
357_D	382_A	0.826	0.67
477_A	532_V	0.823	0.67
360_G	363_D	0.819	0.67
163_E	379_K	0.817	0.66
506_D	577_K	0.817	0.66
477_A	528_Y	0.816	0.66
580_L	617_A	0.816	0.66
191_T	278_T	0.812	0.66
333_V	412_D	0.811	0.66
71_A	269_D	0.810	0.66
643_A	696_H	0.810	0.66
686_I	690_I	0.808	0.66
101_D	104_D	0.807	0.65
637_L	688_R	0.807	0.65
47_T	55_D	0.806	0.65
293_V	300_G	0.806	0.65
700_T	721_V	0.806	0.65
124_A	128_G	0.805	0.65
356_L	359_I	0.805	0.65
141_L	175_V	0.804	0.65
541_T	575_V	0.803	0.65
164_Q	402_L	0.800	0.65
410_A	413_A	0.799	0.65
524_A	583_F	0.798	0.65
73_A	80_S	0.798	0.65
46_R	49_I	0.798	0.65
603_D	660_Y	0.797	0.64
203_V	273_I	0.796	0.64
15_D	171_V	0.796	0.64
524_A	591_Y	0.796	0.64
45_Y	153_F	0.795	0.64
46_R	50_E	0.791	0.64
595_E	627_G	0.790	0.64
124_A	127_A	0.789	0.64
94_E	101_D	0.787	0.63
595_E	699_A	0.787	0.63
313_I	316_D	0.787	0.63
54_I	57_E	0.786	0.63
348_R	360_G	0.784	0.63
262_K	278_T	0.783	0.63
51_E	55_D	0.782	0.63
143_D	147_R	0.780	0.63
695_E	698_V	0.780	0.63
30_A	253_T	0.780	0.63
632_T	663_A	0.780	0.63
442_E	446_I	0.777	0.62
189_L	275_D	0.776	0.62
189_L	293_V	0.776	0.62
505_D	552_D	0.775	0.62
643_A	650_A	0.775	0.62
680_P	684_T	0.775	0.62
348_R	353_L	0.774	0.62
423_V	432_V	0.774	0.62
142_L	146_K	0.772	0.62
225_V	229_T	0.772	0.62
163_E	402_L	0.771	0.62
509_E	581_S	0.769	0.62
250_T	275_D	0.769	0.62
524_A	534_V	0.768	0.62
132_T	213_V	0.768	0.62
500_P	516_L	0.767	0.61
489_M	575_V	0.766	0.61
408_V	500_P	0.766	0.61
614_M	618_G	0.765	0.61
520_I	583_F	0.762	0.61
95_D	101_D	0.762	0.61
136_I	144_H	0.760	0.61
109_F	118_A	0.759	0.61
57_E	82_L	0.758	0.61
56_Q	59_F	0.757	0.60
113_R	117_T	0.756	0.60
433_R	437_E	0.756	0.60
189_L	280_G	0.753	0.60
207_W	221_D	0.753	0.60
359_I	363_D	0.752	0.60
329_G	405_P	0.752	0.60
581_S	621_V	0.752	0.60
43_G	46_R	0.750	0.60
373_D	499_T	0.749	0.60
387_D	413_A	0.748	0.60
474_E	526_E	0.748	0.60
112_V	119_E	0.748	0.60
329_G	431_V	0.746	0.59
63_G	66_A	0.745	0.59
9_V	17_V	0.744	0.59
580_L	610_A	0.744	0.59
460_A	742_E	0.744	0.59
117_T	123_D	0.744	0.59
155_E	376_P	0.743	0.59
540_P	544_F	0.742	0.59
158_I	168_H	0.742	0.59
520_I	586_L	0.741	0.59
46_R	170_R	0.741	0.59
327_G	632_T	0.740	0.59
735_Q	739_K	0.740	0.59
189_L	264_T	0.739	0.59
501_K	504_I	0.738	0.58
207_W	258_V	0.738	0.58
126_F	130_Q	0.737	0.58
602_N	638_A	0.737	0.58
115_S	122_P	0.736	0.58
467_V	726_A	0.736	0.58
355_E	359_I	0.735	0.58
653_G	656_D	0.735	0.58
581_S	617_A	0.734	0.58
605_Q	609_R	0.734	0.58
136_I	139_E	0.733	0.58
142_L	145_V	0.733	0.58
717_V	738_V	0.732	0.58
76_A	80_S	0.731	0.58
702_I	721_V	0.729	0.58
65_D	74_D	0.728	0.57
190_F	214_V	0.727	0.57
326_G	329_G	0.727	0.57
533_R	649_F	0.727	0.57
222_N	227_R	0.725	0.57
153_F	168_H	0.725	0.57
656_D	666_R	0.723	0.57
636_A	700_T	0.722	0.57
40_V	172_N	0.719	0.57
323_N	440_T	0.719	0.57
21_G	39_V	0.717	0.56
561_L	660_Y	0.717	0.56
699_A	722_S	0.717	0.56
707_G	724_I	0.716	0.56
545_R	549_G	0.715	0.56
159_Y	162_Q	0.712	0.56
401_E	472_A	0.710	0.56
44_T	54_I	0.710	0.56
74_D	588_E	0.709	0.55
204_E	336_L	0.706	0.55
329_G	437_E	0.706	0.55
87_D	90_A	0.705	0.55
572_R	575_V	0.703	0.55
165_G	672_A	0.703	0.55
458_M	743_Q	0.701	0.55
629_M	655_N	0.701	0.55
67_E	84_L	0.700	0.54
601_V	607_V	0.700	0.54
333_V	423_V	0.698	0.54
364_I	382_A	0.697	0.54
686_I	702_I	0.696	0.54
629_M	656_D	0.696	0.54
55_D	59_F	0.695	0.54
58_L	61_A	0.694	0.54
139_E	332_V	0.693	0.54
636_A	693_C	0.692	0.54
549_G	553_E	0.692	0.54
443_H	446_I	0.691	0.54
207_W	268_L	0.691	0.54
464_K	699_A	0.689	0.53
46_R	91_S	0.689	0.53
600_L	663_A	0.688	0.53
193_H	201_A	0.688	0.53
227_R	235_A	0.687	0.53
126_F	129_Q	0.687	0.53
474_E	525_E	0.687	0.53
54_I	142_L	0.687	0.53
231_T	238_A	0.686	0.53
83_I	87_D	0.685	0.53
566_V	598_F	0.684	0.53
284_E	447_E	0.683	0.53
207_W	225_V	0.683	0.53
558_N	659_Q	0.682	0.53
491_H	494_L	0.681	0.52
349_V	419_D	0.680	0.52
366_A	423_V	0.680	0.52
106_G	414_T	0.679	0.52
177_V	691_D	0.678	0.52
580_L	618_G	0.677	0.52
356_L	363_D	0.676	0.52
88_F	93_R	0.675	0.52
56_Q	60_D	0.674	0.52
102_A	105_D	0.672	0.52
596_V	614_M	0.672	0.52
643_A	699_A	0.670	0.51
706_A	738_V	0.669	0.51
326_G	433_R	0.669	0.51
375_V	408_V	0.669	0.51
504_I	575_V	0.668	0.51
640_E	696_H	0.667	0.51
125_S	129_Q	0.667	0.51
526_E	529_P	0.666	0.51
379_K	408_V	0.666	0.51
178_Q	699_A	0.666	0.51
494_L	671_V	0.665	0.51
95_D	98_S	0.663	0.51
516_L	520_I	0.663	0.51
592_D	624_R	0.663	0.51
185_K	223_Y	0.663	0.51
150_A	153_F	0.662	0.50
188_V	214_V	0.662	0.50
525_E	591_Y	0.661	0.50
505_D	574_D	0.661	0.50
371_T	378_M	0.661	0.50
628_V	698_V	0.660	0.50
87_D	101_D	0.659	0.50
157_A	161_R	0.659	0.50
231_T	237_V	0.659	0.50
39_V	176_V	0.658	0.50
678_L	702_I	0.657	0.50
302_V	306_Q	0.656	0.50
351_T	355_E	0.656	0.50
326_G	440_T	0.656	0.50
87_D	95_D	0.655	0.50
726_A	734_V	0.655	0.50
121_L	710_P	0.654	0.50
231_T	235_A	0.654	0.50
520_I	524_A	0.654	0.50
34_V	60_D	0.653	0.49
13_D	25_G	0.651	0.49
491_H	600_L	0.650	0.49
123_D	164_Q	0.649	0.49
481_A	530_R	0.649	0.49
655_N	659_Q	0.649	0.49
231_T	236_T	0.648	0.49
65_D	69_S	0.647	0.49
726_A	731_V	0.646	0.49
159_Y	164_Q	0.645	0.49
184_E	297_I	0.644	0.49
387_D	411_T	0.643	0.48
419_D	433_R	0.641	0.48
604_A	607_V	0.640	0.48
113_R	118_A	0.639	0.48
41_T	44_T	0.639	0.48
576_F	580_L	0.638	0.48
683_L	718_E	0.637	0.48
350_V	359_I	0.637	0.48
200_E	205_A	0.635	0.48
612_D	615_A	0.635	0.48
220_P	391_M	0.635	0.48
523_V	526_E	0.635	0.48
468_S	472_A	0.634	0.47
53_G	56_Q	0.632	0.47
307_S	547_L	0.631	0.47
194_P	204_E	0.631	0.47
305_L	419_D	0.631	0.47
230_D	238_A	0.631	0.47
195_S	336_L	0.631	0.47
657_L	685_L	0.630	0.47
221_D	229_T	0.628	0.47
26_E	257_D	0.628	0.47
151_S	214_V	0.627	0.47
494_L	600_L	0.627	0.47
252_E	256_R	0.627	0.47
467_V	476_A	0.626	0.47
112_V	121_L	0.626	0.47
494_L	498_K	0.625	0.47
85_N	93_R	0.625	0.47
33_P	301_D	0.624	0.46
191_T	264_T	0.624	0.46
294_E	300_G	0.624	0.46
350_V	354_D	0.623	0.46
613_L	617_A	0.622	0.46
86_T	101_D	0.622	0.46
203_V	206_A	0.622	0.46
465_V	697_D	0.621	0.46
318_D	442_E	0.621	0.46
113_R	121_L	0.620	0.46
397_I	401_E	0.619	0.46
378_M	494_L	0.618	0.46
672_A	711_E	0.618	0.46
627_G	649_F	0.618	0.46
71_A	80_S	0.617	0.46
407_V	427_G	0.617	0.46
373_D	670_S	0.617	0.46
95_D	104_D	0.617	0.46
534_V	561_L	0.616	0.46
566_V	601_V	0.616	0.46
327_G	438_E	0.615	0.45
673_D	679_H	0.615	0.45
528_Y	592_D	0.615	0.45
664_V	669_G	0.614	0.45
154_T	159_Y	0.613	0.45
71_A	179_R	0.613	0.45
607_V	628_V	0.612	0.45
713_V	717_V	0.612	0.45
740_R	743_Q	0.612	0.45
576_F	609_R	0.612	0.45
107_A	117_T	0.612	0.45
71_A	74_D	0.611	0.45
597_M	651_S	0.611	0.45
286_H	290_P	0.609	0.45
251_G	264_T	0.609	0.45
528_Y	591_Y	0.608	0.45
655_N	666_R	0.607	0.45
463_V	713_V	0.606	0.44
737_E	740_R	0.606	0.44
465_V	484_V	0.606	0.44
371_T	501_K	0.605	0.44
226_D	231_T	0.604	0.44
425_L	695_E	0.603	0.44
615_A	618_G	0.602	0.44
418_C	697_D	0.602	0.44
632_T	662_L	0.602	0.44
275_D	278_T	0.601	0.44
378_M	633_P	0.600	0.44
509_E	578_H	0.599	0.44
463_V	735_Q	0.598	0.44
17_V	39_V	0.598	0.44
716_L	721_V	0.597	0.44
369_M	388_E	0.597	0.44
67_E	71_A	0.597	0.44
81_D	93_R	0.597	0.44
154_T	375_V	0.596	0.43
71_A	274_S	0.596	0.43
16_S	42_A	0.596	0.43
350_V	377_A	0.596	0.43
76_A	158_I	0.596	0.43
459_T	739_K	0.596	0.43
468_S	522_G	0.595	0.43
401_E	469_I	0.595	0.43
494_L	501_K	0.594	0.43
373_D	494_L	0.594	0.43
258_V	262_K	0.594	0.43
190_F	194_P	0.592	0.43
426_D	429_R	0.592	0.43
17_V	25_G	0.591	0.43
46_R	171_V	0.591	0.43
629_M	653_G	0.591	0.43
500_P	547_L	0.591	0.43
462_E	465_V	0.590	0.43
344_S	438_E	0.590	0.43
98_S	101_D	0.589	0.43
125_S	132_T	0.589	0.43
269_D	272_E	0.589	0.43
638_A	642_I	0.588	0.43
287_Y	307_S	0.587	0.43
98_S	103_L	0.587	0.43
202_I	336_L	0.587	0.43
601_V	628_V	0.586	0.42
689_T	692_A	0.586	0.42
459_T	738_V	0.586	0.42
705_Q	727_N	0.586	0.42
225_V	238_A	0.585	0.42
603_D	662_L	0.585	0.42
512_Y	516_L	0.584	0.42
484_V	526_E	0.584	0.42
64_V	138_R	0.584	0.42
66_A	70_D	0.583	0.42
328_G	697_D	0.583	0.42
99_S	177_V	0.582	0.42
15_D	46_R	0.582	0.42
569_S	602_N	0.581	0.42
20_K	210_G	0.581	0.42
343_A	364_I	0.580	0.42
408_V	447_E	0.579	0.42
54_I	193_H	0.579	0.42
310_I	549_G	0.578	0.42
488_R	629_M	0.578	0.42
705_Q	729_D	0.578	0.42
546_Q	549_G	0.577	0.41
256_R	474_E	0.577	0.41
193_H	198_A	0.577	0.41
471_E	523_V	0.576	0.41
602_N	660_Y	0.576	0.41
470_P	523_V	0.575	0.41
15_D	177_V	0.575	0.41
465_V	473_A	0.575	0.41
587_Y	622_E	0.575	0.41
136_I	252_E	0.574	0.41
81_D	101_D	0.573	0.41
201_A	238_A	0.573	0.41
663_A	667_N	0.573	0.41
570_L	610_A	0.572	0.41
309_P	740_R	0.570	0.41
85_N	101_D	0.570	0.41
84_L	147_R	0.569	0.41
185_K	267_V	0.569	0.41
219_S	336_L	0.568	0.41
331_A	437_E	0.567	0.40
110_V	141_L	0.567	0.40
686_I	712_M	0.566	0.40
469_I	522_G	0.566	0.40
130_Q	134_L	0.566	0.40
494_L	499_T	0.566	0.40
735_Q	738_V	0.566	0.40
494_L	673_D	0.566	0.40
188_V	276_L	0.566	0.40
206_A	267_V	0.565	0.40
75_A	80_S	0.565	0.40
356_L	420_D	0.565	0.40
629_M	666_R	0.565	0.40
587_Y	594_V	0.564	0.40
15_D	92_L	0.564	0.40
609_R	613_L	0.563	0.40
54_I	82_L	0.563	0.40
472_A	475_R	0.563	0.40
653_G	666_R	0.562	0.40
597_M	699_A	0.562	0.40
555_H	598_F	0.562	0.40
542_D	560_M	0.561	0.40
631_E	656_D	0.561	0.40
16_S	95_D	0.561	0.40
186_S	215_S	0.560	0.40
83_I	95_D	0.560	0.40
275_D	301_D	0.560	0.40
97_L	141_L	0.560	0.40
631_E	653_G	0.560	0.40
444_D	448_D	0.558	0.40
655_N	703_C	0.558	0.40
190_F	211_E	0.558	0.40
362_G	436_R	0.558	0.40
140_A	574_D	0.557	0.39
151_S	190_F	0.557	0.39
95_D	102_A	0.556	0.39
501_K	670_S	0.556	0.39
540_P	635_A	0.556	0.39
44_T	201_A	0.555	0.39
337_G	456_K	0.554	0.39
382_A	404_C	0.554	0.39
115_S	128_G	0.554	0.39
96_I	203_V	0.554	0.39
108_A	115_S	0.554	0.39
512_Y	572_R	0.553	0.39
81_D	87_D	0.552	0.39
185_K	233_E	0.552	0.39
730_A	735_Q	0.552	0.39
191_T	251_G	0.552	0.39
354_D	358_K	0.551	0.39
405_P	425_L	0.551	0.39
463_V	481_A	0.551	0.39
19_G	188_V	0.551	0.39
545_R	550_G	0.551	0.39
11_A	23_S	0.551	0.39
525_E	588_E	0.551	0.39
656_D	703_C	0.550	0.39
489_M	534_V	0.550	0.39
549_G	624_R	0.550	0.39
307_S	736_H	0.550	0.39
78_R	434_D	0.550	0.39
521_R	585_R	0.549	0.39
640_E	648_D	0.548	0.38
182_D	207_W	0.548	0.38
584_R	622_E	0.548	0.38
631_E	666_R	0.547	0.38
633_P	667_N	0.547	0.38
528_Y	593_N	0.547	0.38
146_K	177_V	0.547	0.38
472_A	476_A	0.547	0.38
521_R	588_E	0.545	0.38
407_V	425_L	0.545	0.38
40_V	74_D	0.545	0.38
38_F	84_L	0.545	0.38
554_P	563_Y	0.544	0.38
514_Q	555_H	0.544	0.38
222_N	225_V	0.544	0.38
327_G	433_R	0.544	0.38
250_T	268_L	0.544	0.38
356_L	399_S	0.543	0.38
307_S	311_T	0.543	0.38
666_R	703_C	0.543	0.38
36_P	475_R	0.543	0.38
636_A	661_T	0.543	0.38
88_F	97_L	0.542	0.38
737_E	741_V	0.542	0.38
23_S	280_G	0.541	0.38
560_M	659_Q	0.541	0.38
563_Y	572_R	0.541	0.38
294_E	553_E	0.541	0.38
63_G	75_A	0.540	0.38
99_S	102_A	0.540	0.38
146_K	529_P	0.539	0.38
12_D	460_A	0.539	0.38
580_L	621_V	0.538	0.37
221_D	226_D	0.538	0.37
256_R	259_P	0.538	0.37
47_T	91_S	0.538	0.37
657_L	686_I	0.537	0.37
629_M	703_C	0.537	0.37
491_H	633_P	0.537	0.37
509_E	572_R	0.536	0.37
88_F	101_D	0.536	0.37
282_R	285_A	0.536	0.37
656_D	659_Q	0.535	0.37
334_T	429_R	0.535	0.37
600_L	633_P	0.534	0.37
706_A	730_A	0.534	0.37
63_G	67_E	0.534	0.37
533_R	595_E	0.534	0.37
287_Y	550_G	0.533	0.37
78_R	416_T	0.532	0.37
496_T	499_T	0.532	0.37
106_G	117_T	0.530	0.37
124_A	284_E	0.530	0.37
42_A	46_R	0.529	0.37
714_D	729_D	0.529	0.37
278_T	282_R	0.529	0.37
89_P	93_R	0.529	0.37
93_R	101_D	0.528	0.36
155_E	165_G	0.527	0.36
188_V	206_A	0.527	0.36
121_L	166_F	0.527	0.36
488_R	655_N	0.527	0.36
356_L	419_D	0.527	0.36
235_A	266_R	0.527	0.36
227_R	238_A	0.526	0.36
109_F	303_Y	0.526	0.36
662_L	742_E	0.526	0.36
82_L	88_F	0.525	0.36
124_A	308_R	0.525	0.36
318_D	339_S	0.525	0.36
613_L	626_W	0.525	0.36
531_P	595_E	0.525	0.36
159_Y	379_K	0.525	0.36
600_L	660_Y	0.524	0.36
223_Y	273_I	0.524	0.36
673_D	676_D	0.524	0.36
210_G	214_V	0.524	0.36
689_T	721_V	0.524	0.36
705_Q	708_S	0.523	0.36
471_E	475_R	0.523	0.36
391_M	401_E	0.523	0.36
313_I	733_D	0.523	0.36
150_A	201_A	0.523	0.36
627_G	635_A	0.522	0.36
74_D	78_R	0.522	0.36
293_V	304_M	0.521	0.36
225_V	232_V	0.521	0.36
501_K	574_D	0.520	0.36
649_F	707_G	0.520	0.36
619_I	623_K	0.520	0.36
536_T	576_F	0.520	0.36
652_F	707_G	0.520	0.36
207_W	226_D	0.520	0.36
140_A	144_H	0.520	0.36
156_R	214_V	0.519	0.36
50_E	691_D	0.518	0.36
87_D	102_A	0.518	0.36
63_G	71_A	0.518	0.36
506_D	574_D	0.518	0.36
405_P	500_P	0.518	0.36
146_K	711_E	0.518	0.36
630_I	650_A	0.518	0.36
488_R	656_D	0.517	0.35
649_F	652_F	0.517	0.35
305_L	740_R	0.517	0.35
577_K	614_M	0.517	0.35
408_V	425_L	0.516	0.35
686_I	699_A	0.516	0.35
47_T	57_E	0.516	0.35
540_P	567_R	0.516	0.35
237_V	334_T	0.516	0.35
687_E	690_I	0.516	0.35
344_S	425_L	0.515	0.35
355_E	440_T	0.515	0.35
156_R	211_E	0.515	0.35
329_G	439_T	0.515	0.35
713_V	724_I	0.515	0.35
186_S	217_A	0.515	0.35
692_A	698_V	0.514	0.35
342_V	439_T	0.514	0.35
201_A	237_V	0.513	0.35
658_T	675_F	0.513	0.35
734_V	738_V	0.512	0.35
56_Q	62_V	0.512	0.35
567_R	649_F	0.511	0.35
8_D	484_V	0.511	0.35
97_L	102_A	0.511	0.35
633_P	660_Y	0.511	0.35
549_G	593_N	0.511	0.35
371_T	670_S	0.511	0.35
74_D	687_E	0.510	0.35
376_P	424_T	0.510	0.35
350_V	356_L	0.510	0.35
571_D	576_F	0.509	0.35
703_C	725_S	0.508	0.35
146_K	153_F	0.507	0.34
333_V	404_C	0.507	0.34
202_I	337_G	0.507	0.34
331_A	334_T	0.507	0.34
223_Y	251_G	0.507	0.34
85_N	89_P	0.507	0.34
61_A	70_D	0.506	0.34
626_W	662_L	0.506	0.34
464_K	625_S	0.506	0.34
473_A	526_E	0.506	0.34
631_E	655_N	0.506	0.34
118_A	304_M	0.505	0.34
151_S	211_E	0.505	0.34
506_D	687_E	0.505	0.34
121_L	157_A	0.505	0.34
49_I	407_V	0.504	0.34
547_L	550_G	0.504	0.34
320_A	339_S	0.504	0.34
23_S	26_E	0.504	0.34
230_D	237_V	0.504	0.34
64_V	75_A	0.504	0.34
333_V	413_A	0.504	0.34
76_A	155_E	0.503	0.34
501_K	563_Y	0.503	0.34
126_F	232_V	0.503	0.34
72_L	80_S	0.503	0.34
140_A	317_T	0.502	0.34
556_E	560_M	0.502	0.34
184_E	272_E	0.501	0.34
139_E	142_L	0.501	0.34
225_V	311_T	0.501	0.34
463_V	731_V	0.501	0.34
66_A	256_R	0.501	0.34
112_V	116_A	0.501	0.34
80_S	154_T	0.501	0.34
194_P	397_I	0.500	0.34

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1vbgA	2	0.9654	100	0.304	Contact Map
2x0sA	2	0.9867	100	0.306	Contact Map
1kblA	2	0.9734	100	0.306	Contact Map
2olsA	2	0.8936	100	0.311	Contact Map
2hwgA	2	0.6941	100	0.637	Contact Map
2wqdA	2	0.6955	100	0.649	Contact Map
2xz9A	2	0.383	100	0.77	Contact Map
4l9zA	5	0.3364	100	0.881	Contact Map
4roqA	5	0.3378	100	0.887	Contact Map
3qz6A	5	0.3045	100	0.888	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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