GREMLIN Database
Q9HSA1 - Phosphoenolpyruvate synthase
UniProt: Q9HSA1 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 752 (714)
Sequences: 2726 (1449)
Seq/√Len: 54.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
347_A417_L6.9921.00
383_G425_L4.9561.00
648_D695_E4.6781.00
346_P361_E4.3801.00
684_T692_A4.1081.00
288_D292_D3.9991.00
687_E691_D3.7881.00
300_G457_P3.7801.00
702_I716_L3.6351.00
525_E589_M3.5471.00
362_G382_A3.5421.00
126_F132_T3.4781.00
299_D302_V3.4021.00
598_F614_M3.3201.00
536_T598_F3.2571.00
205_A267_V3.2101.00
502_R515_E3.1991.00
105_D114_S3.1651.00
563_Y571_D3.1531.00
117_T121_L3.0671.00
632_T660_Y3.0651.00
506_D510_D2.9921.00
640_E692_A2.9831.00
116_A121_L2.9781.00
477_A530_R2.9471.00
118_A121_L2.9001.00
321_V424_T2.8891.00
183_A270_D2.8421.00
212_A255_S2.8361.00
461_T717_V2.7721.00
91_S171_V2.7681.00
105_D109_F2.7441.00
510_D514_Q2.7421.00
110_V114_S2.7271.00
109_F114_S2.6571.00
686_I719_T2.6531.00
417_L434_D2.6211.00
111_A114_S2.6121.00
352_S419_D2.6091.00
611_R615_A2.5991.00
690_I700_T2.5841.00
422_A436_R2.5781.00
105_D110_V2.5291.00
620_D623_K2.4881.00
569_S576_F2.4391.00
677_E709_K2.4391.00
510_D577_K2.3891.00
527_F532_V2.3791.00
330_D434_D2.3691.00
110_V116_A2.3411.00
74_D77_A2.3291.00
115_S121_L2.3191.00
167_D170_R2.3131.00
105_D111_A2.2751.00
347_A423_V2.2291.00
10_R29_D2.2141.00
583_F596_V2.1941.00
577_K616_D2.1851.00
331_A433_R2.1841.00
641_E684_T2.1751.00
586_L594_V2.1611.00
108_A120_D2.1471.00
73_A269_D2.1401.00
615_A626_W2.0941.00
162_Q168_H2.0921.00
459_T482_D2.0921.00
576_F610_A2.0901.00
684_T688_R2.0741.00
462_E482_D2.0291.00
456_K459_T2.0251.00
630_I689_T2.0121.00
47_T51_E2.0071.00
602_N632_T1.9971.00
116_A120_D1.9821.00
115_S118_A1.9701.00
595_E625_S1.9681.00
364_I383_G1.9631.00
107_A111_A1.9521.00
460_A717_V1.9361.00
347_A434_D1.9301.00
304_M458_M1.9291.00
334_T431_V1.9221.00
364_I423_V1.9221.00
234_E238_A1.9131.00
108_A114_S1.8960.99
474_E478_A1.8960.99
385_V425_L1.8860.99
110_V115_S1.8850.99
523_V532_V1.8840.99
680_P718_E1.8820.99
637_L685_L1.8740.99
577_K613_L1.8710.99
348_R356_L1.8670.99
107_A110_V1.8660.99
522_G526_E1.8620.99
15_D91_S1.8570.99
634_A681_S1.8570.99
333_V410_A1.8440.99
714_D718_E1.8280.99
689_T700_T1.8200.99
464_K595_E1.8130.99
661_T682_V1.8100.99
206_A213_V1.8020.99
684_T687_E1.7850.99
125_S131_E1.7780.99
347_A366_A1.7780.99
355_E358_K1.7760.99
346_P422_A1.7720.99
333_V432_V1.7610.99
232_V238_A1.7610.99
110_V121_L1.7570.99
58_L79_A1.7470.99
693_C698_V1.7400.99
117_T120_D1.7300.99
475_R478_A1.7280.99
233_E238_A1.7220.99
615_A619_I1.7160.99
584_R618_G1.7150.99
477_A526_E1.7110.99
518_D522_G1.7090.99
618_G626_W1.7040.99
288_D447_E1.7040.99
36_P179_R1.7010.99
577_K617_A1.6830.99
109_F112_V1.6780.99
521_R525_E1.6780.99
201_A251_G1.6740.99
533_R699_A1.6730.99
505_D508_G1.6620.99
612_D616_D1.6600.99
107_A114_S1.6570.99
106_G110_V1.6510.99
71_A75_A1.6380.99
661_T685_L1.6230.98
484_V527_F1.6190.98
687_E719_T1.6180.98
686_I716_L1.6180.98
336_L391_M1.6130.98
473_A527_F1.6100.98
299_D303_Y1.6020.98
205_A229_T1.5950.98
193_H200_E1.5910.98
92_L171_V1.5860.98
232_V235_A1.5850.98
641_E644_Q1.5840.98
580_L614_M1.5810.98
351_T376_P1.5810.98
225_V228_D1.5750.98
301_D458_M1.5670.98
605_Q608_A1.5630.98
415_T434_D1.5590.98
55_D58_L1.5550.98
677_E711_E1.5530.98
638_A641_E1.5520.98
16_S41_T1.5520.98
456_K735_Q1.5460.98
611_R648_D1.5410.98
50_E55_D1.5400.98
536_T583_F1.5320.98
106_G109_F1.5260.98
62_V145_V1.5240.98
16_S43_G1.5180.98
352_S356_L1.5180.98
617_A620_D1.4980.97
115_S120_D1.4950.97
620_D624_R1.4920.97
521_R589_M1.4840.97
694_R722_S1.4830.97
458_M742_E1.4760.97
261_R280_G1.4710.97
368_E387_D1.4600.97
105_D121_L1.4550.97
637_L684_T1.4540.97
473_A523_V1.4520.97
110_V113_R1.4450.97
616_D620_D1.4440.97
191_T293_V1.4440.97
585_R621_V1.4360.97
108_A111_A1.4300.96
230_D233_E1.4180.96
189_L237_V1.4180.96
473_A532_V1.4080.96
146_K150_A1.4080.96
234_E237_V1.4060.96
524_A594_V1.4020.96
604_A638_A1.3990.96
581_S585_R1.3970.96
687_E718_E1.3960.96
283_V304_M1.3920.96
322_A438_E1.3890.96
9_V13_D1.3830.96
502_R511_A1.3810.96
205_A225_V1.3810.96
378_M384_I1.3800.96
605_Q679_H1.3790.96
105_D112_V1.3790.96
159_Y163_E1.3790.96
344_S436_R1.3790.96
259_P302_V1.3770.96
105_D108_A1.3760.96
517_V585_R1.3740.96
296_A305_L1.3680.95
93_R97_L1.3580.95
484_V523_V1.3530.95
298_V306_Q1.3470.95
608_A612_D1.3440.95
354_D376_P1.3420.95
236_T239_D1.3400.95
167_D171_V1.3400.95
81_D85_N1.3390.95
580_L584_R1.3380.95
686_I689_T1.3370.95
322_A440_T1.3300.95
110_V117_T1.3200.94
418_C421_Q1.3160.94
118_A122_P1.3070.94
153_F158_I1.2990.94
205_A223_Y1.2950.94
91_S170_R1.2930.94
507_H510_D1.2900.94
619_I622_E1.2900.94
52_A86_T1.2860.94
57_E60_D1.2850.94
112_V115_S1.2840.94
106_G111_A1.2810.93
348_R363_D1.2810.93
463_V724_I1.2790.93
59_F142_L1.2780.93
510_D585_R1.2720.93
356_L361_E1.2680.93
566_V610_A1.2680.93
62_V142_L1.2660.93
139_E143_D1.2650.93
105_D116_A1.2630.93
145_V175_V1.2620.93
90_A93_R1.2610.93
204_E391_M1.2610.93
10_R13_D1.2550.93
106_G114_S1.2520.93
630_I636_A1.2420.92
259_P262_K1.2410.92
111_A117_T1.2400.92
678_L716_L1.2390.92
235_A238_A1.2350.92
111_A115_S1.2330.92
159_Y375_V1.2280.92
221_D225_V1.2280.92
272_E297_I1.2270.92
300_G458_M1.2270.92
602_N664_V1.2260.92
644_Q696_H1.2240.92
584_R596_V1.2180.92
621_V624_R1.2170.92
604_A608_A1.2140.91
717_V742_E1.2140.91
607_V647_V1.2130.91
534_V583_F1.2100.91
468_S487_L1.2080.91
375_V402_L1.2020.91
688_R692_A1.2010.91
477_A527_F1.1950.91
615_A620_D1.1950.91
47_T50_E1.1930.91
111_A116_A1.1910.91
305_L743_Q1.1900.91
602_N662_L1.1890.91
116_A119_E1.1890.91
105_D117_T1.1880.91
475_R729_D1.1850.90
614_M626_W1.1840.90
105_D113_R1.1740.90
613_L616_D1.1560.89
660_Y676_D1.1510.89
672_A677_E1.1490.89
113_R116_A1.1490.89
683_L715_F1.1440.89
603_D638_A1.1430.89
358_K419_D1.1420.89
364_I425_L1.1420.89
641_E680_P1.1370.89
124_A129_Q1.1360.89
105_D115_S1.1360.89
54_I58_L1.1300.88
314_E318_D1.1290.88
46_R55_D1.1280.88
550_G553_E1.1280.88
339_S397_I1.1270.88
670_S673_D1.1270.88
192_S199_H1.1260.88
465_V476_A1.1260.88
640_E695_E1.1150.88
344_S439_T1.1150.88
110_V118_A1.1140.88
291_Q294_E1.1130.87
542_D667_N1.1120.87
57_E61_A1.1110.87
332_V417_L1.1060.87
417_L423_V1.1040.87
327_G437_E1.1040.87
109_F121_L1.1010.87
691_D719_T1.1010.87
107_A115_S1.0970.87
585_R588_E1.0910.86
638_A692_A1.0910.86
482_D530_R1.0880.86
46_R172_N1.0860.86
109_F116_A1.0840.86
111_A121_L1.0820.86
114_S117_T1.0820.86
114_S120_D1.0800.86
110_V120_D1.0770.86
131_E139_E1.0770.86
426_D431_V1.0760.86
421_Q434_D1.0750.86
337_G391_M1.0750.86
581_S624_R1.0750.86
331_A431_V1.0710.85
28_T36_P1.0670.85
232_V237_V1.0650.85
570_L609_R1.0640.85
520_I596_V1.0620.85
463_V738_V1.0610.85
186_S213_V1.0590.85
262_K265_Q1.0590.85
639_I689_T1.0570.85
618_G622_E1.0560.85
321_V439_T1.0560.85
191_T280_G1.0550.85
94_E98_S1.0510.84
501_K575_V1.0510.84
353_L363_D1.0460.84
7_E36_P1.0440.84
109_F113_R1.0430.84
107_A112_V1.0420.84
226_D268_L1.0400.84
690_I721_V1.0380.84
604_A644_Q1.0350.83
534_V594_V1.0340.83
155_E159_Y1.0330.83
678_L709_K1.0320.83
108_A117_T1.0300.83
25_G39_V1.0300.83
417_L421_Q1.0300.83
715_F719_T1.0270.83
233_E237_V1.0260.83
223_Y267_V1.0260.83
368_E388_E1.0230.83
643_A698_V1.0190.82
461_T742_E1.0190.82
569_S610_A1.0160.82
90_A94_E1.0150.82
615_A648_D1.0140.82
330_D415_T1.0100.82
105_D118_A1.0080.82
92_L154_T1.0070.82
204_E219_S1.0060.82
598_F610_A1.0020.81
106_G112_V1.0010.81
471_E495_S0.9970.81
114_S121_L0.9960.81
39_V174_A0.9940.81
22_A26_E0.9920.81
465_V731_V0.9920.81
231_T234_E0.9910.81
611_R695_E0.9830.80
412_D416_T0.9750.79
199_H251_G0.9730.79
185_K207_W0.9720.79
108_A112_V0.9680.79
604_A641_E0.9670.79
224_V227_R0.9600.78
633_P663_A0.9600.78
680_P683_L0.9600.78
233_E236_T0.9590.78
233_E268_L0.9590.78
91_S167_D0.9570.78
576_F613_L0.9560.78
678_L711_E0.9540.78
385_V432_V0.9530.78
185_K268_L0.9510.78
514_Q581_S0.9460.77
632_T664_V0.9420.77
226_D234_E0.9400.77
361_E380_R0.9390.77
352_S355_E0.9390.77
109_F115_S0.9370.77
548_E551_N0.9340.76
163_E375_V0.9330.76
226_D230_D0.9330.76
159_Y376_P0.9320.76
232_V236_T0.9290.76
536_T596_V0.9260.76
299_D305_L0.9260.76
109_F117_T0.9260.76
226_D229_T0.9260.76
112_V117_T0.9250.76
332_V415_T0.9230.76
43_G47_T0.9230.76
692_A696_H0.9220.76
237_V266_R0.9190.75
610_A613_L0.9130.75
321_V326_G0.9130.75
117_T122_P0.9120.75
641_E692_A0.9110.75
7_E70_D0.9100.75
11_A14_I0.9090.75
108_A116_A0.9080.74
634_A679_H0.9070.74
473_A477_A0.9060.74
143_D146_K0.9040.74
609_R612_D0.9030.74
230_D234_E0.9030.74
487_L523_V0.9020.74
459_T735_Q0.9020.74
477_A529_P0.8980.74
379_K402_L0.8950.73
680_P711_E0.8930.73
660_Y664_V0.8920.73
373_D501_K0.8900.73
204_E220_P0.8860.73
235_A239_D0.8850.73
660_Y663_A0.8840.72
226_D233_E0.8820.72
509_E512_Y0.8820.72
206_A212_A0.8810.72
460_A722_S0.8780.72
639_I650_A0.8760.72
329_G433_R0.8750.72
636_A689_T0.8750.72
650_A693_C0.8750.72
65_D68_D0.8730.71
308_R311_T0.8720.71
638_A684_T0.8710.71
256_R297_I0.8660.71
97_L101_D0.8650.71
576_F598_F0.8650.71
104_D108_A0.8620.71
652_F689_T0.8610.70
482_D735_Q0.8610.70
494_L670_S0.8600.70
194_P202_I0.8600.70
68_D71_A0.8590.70
509_E513_V0.8590.70
9_V12_D0.8570.70
385_V423_V0.8560.70
333_V417_L0.8550.70
54_I146_K0.8540.70
413_A417_L0.8510.70
154_T158_I0.8500.69
61_A78_R0.8490.69
636_A685_L0.8480.69
346_P356_L0.8470.69
470_P522_G0.8440.69
211_E214_V0.8440.69
376_P405_P0.8420.69
625_S699_A0.8400.69
405_P433_R0.8390.68
239_D253_T0.8390.68
709_K713_V0.8380.68
49_I83_I0.8350.68
119_E122_P0.8340.68
200_E224_V0.8330.68
601_V632_T0.8320.68
371_T494_L0.8320.68
291_Q307_S0.8310.68
87_D93_R0.8280.67
82_L85_N0.8270.67
611_R626_W0.8270.67
357_D382_A0.8260.67
477_A532_V0.8230.67
360_G363_D0.8190.67
163_E379_K0.8170.66
506_D577_K0.8170.66
477_A528_Y0.8160.66
580_L617_A0.8160.66
191_T278_T0.8120.66
333_V412_D0.8110.66
71_A269_D0.8100.66
643_A696_H0.8100.66
686_I690_I0.8080.66
101_D104_D0.8070.65
637_L688_R0.8070.65
47_T55_D0.8060.65
293_V300_G0.8060.65
700_T721_V0.8060.65
124_A128_G0.8050.65
356_L359_I0.8050.65
141_L175_V0.8040.65
541_T575_V0.8030.65
164_Q402_L0.8000.65
410_A413_A0.7990.65
524_A583_F0.7980.65
73_A80_S0.7980.65
46_R49_I0.7980.65
603_D660_Y0.7970.64
203_V273_I0.7960.64
15_D171_V0.7960.64
524_A591_Y0.7960.64
45_Y153_F0.7950.64
46_R50_E0.7910.64
595_E627_G0.7900.64
124_A127_A0.7890.64
94_E101_D0.7870.63
595_E699_A0.7870.63
313_I316_D0.7870.63
54_I57_E0.7860.63
348_R360_G0.7840.63
262_K278_T0.7830.63
51_E55_D0.7820.63
143_D147_R0.7800.63
695_E698_V0.7800.63
30_A253_T0.7800.63
632_T663_A0.7800.63
442_E446_I0.7770.62
189_L275_D0.7760.62
189_L293_V0.7760.62
505_D552_D0.7750.62
643_A650_A0.7750.62
680_P684_T0.7750.62
348_R353_L0.7740.62
423_V432_V0.7740.62
142_L146_K0.7720.62
225_V229_T0.7720.62
163_E402_L0.7710.62
509_E581_S0.7690.62
250_T275_D0.7690.62
524_A534_V0.7680.62
132_T213_V0.7680.62
500_P516_L0.7670.61
489_M575_V0.7660.61
408_V500_P0.7660.61
614_M618_G0.7650.61
520_I583_F0.7620.61
95_D101_D0.7620.61
136_I144_H0.7600.61
109_F118_A0.7590.61
57_E82_L0.7580.61
56_Q59_F0.7570.60
113_R117_T0.7560.60
433_R437_E0.7560.60
189_L280_G0.7530.60
207_W221_D0.7530.60
359_I363_D0.7520.60
329_G405_P0.7520.60
581_S621_V0.7520.60
43_G46_R0.7500.60
373_D499_T0.7490.60
387_D413_A0.7480.60
474_E526_E0.7480.60
112_V119_E0.7480.60
329_G431_V0.7460.59
63_G66_A0.7450.59
9_V17_V0.7440.59
580_L610_A0.7440.59
460_A742_E0.7440.59
117_T123_D0.7440.59
155_E376_P0.7430.59
540_P544_F0.7420.59
158_I168_H0.7420.59
520_I586_L0.7410.59
46_R170_R0.7410.59
327_G632_T0.7400.59
735_Q739_K0.7400.59
189_L264_T0.7390.59
501_K504_I0.7380.58
207_W258_V0.7380.58
126_F130_Q0.7370.58
602_N638_A0.7370.58
115_S122_P0.7360.58
467_V726_A0.7360.58
355_E359_I0.7350.58
653_G656_D0.7350.58
581_S617_A0.7340.58
605_Q609_R0.7340.58
136_I139_E0.7330.58
142_L145_V0.7330.58
717_V738_V0.7320.58
76_A80_S0.7310.58
702_I721_V0.7290.58
65_D74_D0.7280.57
190_F214_V0.7270.57
326_G329_G0.7270.57
533_R649_F0.7270.57
222_N227_R0.7250.57
153_F168_H0.7250.57
656_D666_R0.7230.57
636_A700_T0.7220.57
40_V172_N0.7190.57
323_N440_T0.7190.57
21_G39_V0.7170.56
561_L660_Y0.7170.56
699_A722_S0.7170.56
707_G724_I0.7160.56
545_R549_G0.7150.56
159_Y162_Q0.7120.56
401_E472_A0.7100.56
44_T54_I0.7100.56
74_D588_E0.7090.55
204_E336_L0.7060.55
329_G437_E0.7060.55
87_D90_A0.7050.55
572_R575_V0.7030.55
165_G672_A0.7030.55
458_M743_Q0.7010.55
629_M655_N0.7010.55
67_E84_L0.7000.54
601_V607_V0.7000.54
333_V423_V0.6980.54
364_I382_A0.6970.54
686_I702_I0.6960.54
629_M656_D0.6960.54
55_D59_F0.6950.54
58_L61_A0.6940.54
139_E332_V0.6930.54
636_A693_C0.6920.54
549_G553_E0.6920.54
443_H446_I0.6910.54
207_W268_L0.6910.54
464_K699_A0.6890.53
46_R91_S0.6890.53
600_L663_A0.6880.53
193_H201_A0.6880.53
227_R235_A0.6870.53
126_F129_Q0.6870.53
474_E525_E0.6870.53
54_I142_L0.6870.53
231_T238_A0.6860.53
83_I87_D0.6850.53
566_V598_F0.6840.53
284_E447_E0.6830.53
207_W225_V0.6830.53
558_N659_Q0.6820.53
491_H494_L0.6810.52
349_V419_D0.6800.52
366_A423_V0.6800.52
106_G414_T0.6790.52
177_V691_D0.6780.52
580_L618_G0.6770.52
356_L363_D0.6760.52
88_F93_R0.6750.52
56_Q60_D0.6740.52
102_A105_D0.6720.52
596_V614_M0.6720.52
643_A699_A0.6700.51
706_A738_V0.6690.51
326_G433_R0.6690.51
375_V408_V0.6690.51
504_I575_V0.6680.51
640_E696_H0.6670.51
125_S129_Q0.6670.51
526_E529_P0.6660.51
379_K408_V0.6660.51
178_Q699_A0.6660.51
494_L671_V0.6650.51
95_D98_S0.6630.51
516_L520_I0.6630.51
592_D624_R0.6630.51
185_K223_Y0.6630.51
150_A153_F0.6620.50
188_V214_V0.6620.50
525_E591_Y0.6610.50
505_D574_D0.6610.50
371_T378_M0.6610.50
628_V698_V0.6600.50
87_D101_D0.6590.50
157_A161_R0.6590.50
231_T237_V0.6590.50
39_V176_V0.6580.50
678_L702_I0.6570.50
302_V306_Q0.6560.50
351_T355_E0.6560.50
326_G440_T0.6560.50
87_D95_D0.6550.50
726_A734_V0.6550.50
121_L710_P0.6540.50
231_T235_A0.6540.50
520_I524_A0.6540.50
34_V60_D0.6530.49
13_D25_G0.6510.49
491_H600_L0.6500.49
123_D164_Q0.6490.49
481_A530_R0.6490.49
655_N659_Q0.6490.49
231_T236_T0.6480.49
65_D69_S0.6470.49
726_A731_V0.6460.49
159_Y164_Q0.6450.49
184_E297_I0.6440.49
387_D411_T0.6430.48
419_D433_R0.6410.48
604_A607_V0.6400.48
113_R118_A0.6390.48
41_T44_T0.6390.48
576_F580_L0.6380.48
683_L718_E0.6370.48
350_V359_I0.6370.48
200_E205_A0.6350.48
612_D615_A0.6350.48
220_P391_M0.6350.48
523_V526_E0.6350.48
468_S472_A0.6340.47
53_G56_Q0.6320.47
307_S547_L0.6310.47
194_P204_E0.6310.47
305_L419_D0.6310.47
230_D238_A0.6310.47
195_S336_L0.6310.47
657_L685_L0.6300.47
221_D229_T0.6280.47
26_E257_D0.6280.47
151_S214_V0.6270.47
494_L600_L0.6270.47
252_E256_R0.6270.47
467_V476_A0.6260.47
112_V121_L0.6260.47
494_L498_K0.6250.47
85_N93_R0.6250.47
33_P301_D0.6240.46
191_T264_T0.6240.46
294_E300_G0.6240.46
350_V354_D0.6230.46
613_L617_A0.6220.46
86_T101_D0.6220.46
203_V206_A0.6220.46
465_V697_D0.6210.46
318_D442_E0.6210.46
113_R121_L0.6200.46
397_I401_E0.6190.46
378_M494_L0.6180.46
672_A711_E0.6180.46
627_G649_F0.6180.46
71_A80_S0.6170.46
407_V427_G0.6170.46
373_D670_S0.6170.46
95_D104_D0.6170.46
534_V561_L0.6160.46
566_V601_V0.6160.46
327_G438_E0.6150.45
673_D679_H0.6150.45
528_Y592_D0.6150.45
664_V669_G0.6140.45
154_T159_Y0.6130.45
71_A179_R0.6130.45
607_V628_V0.6120.45
713_V717_V0.6120.45
740_R743_Q0.6120.45
576_F609_R0.6120.45
107_A117_T0.6120.45
71_A74_D0.6110.45
597_M651_S0.6110.45
286_H290_P0.6090.45
251_G264_T0.6090.45
528_Y591_Y0.6080.45
655_N666_R0.6070.45
463_V713_V0.6060.44
737_E740_R0.6060.44
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226_D231_T0.6040.44
425_L695_E0.6030.44
615_A618_G0.6020.44
418_C697_D0.6020.44
632_T662_L0.6020.44
275_D278_T0.6010.44
378_M633_P0.6000.44
509_E578_H0.5990.44
463_V735_Q0.5980.44
17_V39_V0.5980.44
716_L721_V0.5970.44
369_M388_E0.5970.44
67_E71_A0.5970.44
81_D93_R0.5970.44
154_T375_V0.5960.43
71_A274_S0.5960.43
16_S42_A0.5960.43
350_V377_A0.5960.43
76_A158_I0.5960.43
459_T739_K0.5960.43
468_S522_G0.5950.43
401_E469_I0.5950.43
494_L501_K0.5940.43
373_D494_L0.5940.43
258_V262_K0.5940.43
190_F194_P0.5920.43
426_D429_R0.5920.43
17_V25_G0.5910.43
46_R171_V0.5910.43
629_M653_G0.5910.43
500_P547_L0.5910.43
462_E465_V0.5900.43
344_S438_E0.5900.43
98_S101_D0.5890.43
125_S132_T0.5890.43
269_D272_E0.5890.43
638_A642_I0.5880.43
287_Y307_S0.5870.43
98_S103_L0.5870.43
202_I336_L0.5870.43
601_V628_V0.5860.42
689_T692_A0.5860.42
459_T738_V0.5860.42
705_Q727_N0.5860.42
225_V238_A0.5850.42
603_D662_L0.5850.42
512_Y516_L0.5840.42
484_V526_E0.5840.42
64_V138_R0.5840.42
66_A70_D0.5830.42
328_G697_D0.5830.42
99_S177_V0.5820.42
15_D46_R0.5820.42
569_S602_N0.5810.42
20_K210_G0.5810.42
343_A364_I0.5800.42
408_V447_E0.5790.42
54_I193_H0.5790.42
310_I549_G0.5780.42
488_R629_M0.5780.42
705_Q729_D0.5780.42
546_Q549_G0.5770.41
256_R474_E0.5770.41
193_H198_A0.5770.41
471_E523_V0.5760.41
602_N660_Y0.5760.41
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15_D177_V0.5750.41
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587_Y622_E0.5750.41
136_I252_E0.5740.41
81_D101_D0.5730.41
201_A238_A0.5730.41
663_A667_N0.5730.41
570_L610_A0.5720.41
309_P740_R0.5700.41
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686_I712_M0.5660.40
469_I522_G0.5660.40
130_Q134_L0.5660.40
494_L499_T0.5660.40
735_Q738_V0.5660.40
494_L673_D0.5660.40
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206_A267_V0.5650.40
75_A80_S0.5650.40
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653_G666_R0.5620.40
597_M699_A0.5620.40
555_H598_F0.5620.40
542_D560_M0.5610.40
631_E656_D0.5610.40
16_S95_D0.5610.40
186_S215_S0.5600.40
83_I95_D0.5600.40
275_D301_D0.5600.40
97_L141_L0.5600.40
631_E653_G0.5600.40
444_D448_D0.5580.40
655_N703_C0.5580.40
190_F211_E0.5580.40
362_G436_R0.5580.40
140_A574_D0.5570.39
151_S190_F0.5570.39
95_D102_A0.5560.39
501_K670_S0.5560.39
540_P635_A0.5560.39
44_T201_A0.5550.39
337_G456_K0.5540.39
382_A404_C0.5540.39
115_S128_G0.5540.39
96_I203_V0.5540.39
108_A115_S0.5540.39
512_Y572_R0.5530.39
81_D87_D0.5520.39
185_K233_E0.5520.39
730_A735_Q0.5520.39
191_T251_G0.5520.39
354_D358_K0.5510.39
405_P425_L0.5510.39
463_V481_A0.5510.39
19_G188_V0.5510.39
545_R550_G0.5510.39
11_A23_S0.5510.39
525_E588_E0.5510.39
656_D703_C0.5500.39
489_M534_V0.5500.39
549_G624_R0.5500.39
307_S736_H0.5500.39
78_R434_D0.5500.39
521_R585_R0.5490.39
640_E648_D0.5480.38
182_D207_W0.5480.38
584_R622_E0.5480.38
631_E666_R0.5470.38
633_P667_N0.5470.38
528_Y593_N0.5470.38
146_K177_V0.5470.38
472_A476_A0.5470.38
521_R588_E0.5450.38
407_V425_L0.5450.38
40_V74_D0.5450.38
38_F84_L0.5450.38
554_P563_Y0.5440.38
514_Q555_H0.5440.38
222_N225_V0.5440.38
327_G433_R0.5440.38
250_T268_L0.5440.38
356_L399_S0.5430.38
307_S311_T0.5430.38
666_R703_C0.5430.38
36_P475_R0.5430.38
636_A661_T0.5430.38
88_F97_L0.5420.38
737_E741_V0.5420.38
23_S280_G0.5410.38
560_M659_Q0.5410.38
563_Y572_R0.5410.38
294_E553_E0.5410.38
63_G75_A0.5400.38
99_S102_A0.5400.38
146_K529_P0.5390.38
12_D460_A0.5390.38
580_L621_V0.5380.37
221_D226_D0.5380.37
256_R259_P0.5380.37
47_T91_S0.5380.37
657_L686_I0.5370.37
629_M703_C0.5370.37
491_H633_P0.5370.37
509_E572_R0.5360.37
88_F101_D0.5360.37
282_R285_A0.5360.37
656_D659_Q0.5350.37
334_T429_R0.5350.37
600_L633_P0.5340.37
706_A730_A0.5340.37
63_G67_E0.5340.37
533_R595_E0.5340.37
287_Y550_G0.5330.37
78_R416_T0.5320.37
496_T499_T0.5320.37
106_G117_T0.5300.37
124_A284_E0.5300.37
42_A46_R0.5290.37
714_D729_D0.5290.37
278_T282_R0.5290.37
89_P93_R0.5290.37
93_R101_D0.5280.36
155_E165_G0.5270.36
188_V206_A0.5270.36
121_L166_F0.5270.36
488_R655_N0.5270.36
356_L419_D0.5270.36
235_A266_R0.5270.36
227_R238_A0.5260.36
109_F303_Y0.5260.36
662_L742_E0.5260.36
82_L88_F0.5250.36
124_A308_R0.5250.36
318_D339_S0.5250.36
613_L626_W0.5250.36
531_P595_E0.5250.36
159_Y379_K0.5250.36
600_L660_Y0.5240.36
223_Y273_I0.5240.36
673_D676_D0.5240.36
210_G214_V0.5240.36
689_T721_V0.5240.36
705_Q708_S0.5230.36
471_E475_R0.5230.36
391_M401_E0.5230.36
313_I733_D0.5230.36
150_A201_A0.5230.36
627_G635_A0.5220.36
74_D78_R0.5220.36
293_V304_M0.5210.36
225_V232_V0.5210.36
501_K574_D0.5200.36
649_F707_G0.5200.36
619_I623_K0.5200.36
536_T576_F0.5200.36
652_F707_G0.5200.36
207_W226_D0.5200.36
140_A144_H0.5200.36
156_R214_V0.5190.36
50_E691_D0.5180.36
87_D102_A0.5180.36
63_G71_A0.5180.36
506_D574_D0.5180.36
405_P500_P0.5180.36
146_K711_E0.5180.36
630_I650_A0.5180.36
488_R656_D0.5170.35
649_F652_F0.5170.35
305_L740_R0.5170.35
577_K614_M0.5170.35
408_V425_L0.5160.35
686_I699_A0.5160.35
47_T57_E0.5160.35
540_P567_R0.5160.35
237_V334_T0.5160.35
687_E690_I0.5160.35
344_S425_L0.5150.35
355_E440_T0.5150.35
156_R211_E0.5150.35
329_G439_T0.5150.35
713_V724_I0.5150.35
186_S217_A0.5150.35
692_A698_V0.5140.35
342_V439_T0.5140.35
201_A237_V0.5130.35
658_T675_F0.5130.35
734_V738_V0.5120.35
56_Q62_V0.5120.35
567_R649_F0.5110.35
8_D484_V0.5110.35
97_L102_A0.5110.35
633_P660_Y0.5110.35
549_G593_N0.5110.35
371_T670_S0.5110.35
74_D687_E0.5100.35
376_P424_T0.5100.35
350_V356_L0.5100.35
571_D576_F0.5090.35
703_C725_S0.5080.35
146_K153_F0.5070.34
333_V404_C0.5070.34
202_I337_G0.5070.34
331_A334_T0.5070.34
223_Y251_G0.5070.34
85_N89_P0.5070.34
61_A70_D0.5060.34
626_W662_L0.5060.34
464_K625_S0.5060.34
473_A526_E0.5060.34
631_E655_N0.5060.34
118_A304_M0.5050.34
151_S211_E0.5050.34
506_D687_E0.5050.34
121_L157_A0.5050.34
49_I407_V0.5040.34
547_L550_G0.5040.34
320_A339_S0.5040.34
23_S26_E0.5040.34
230_D237_V0.5040.34
64_V75_A0.5040.34
333_V413_A0.5040.34
76_A155_E0.5030.34
501_K563_Y0.5030.34
126_F232_V0.5030.34
72_L80_S0.5030.34
140_A317_T0.5020.34
556_E560_M0.5020.34
184_E272_E0.5010.34
139_E142_L0.5010.34
225_V311_T0.5010.34
463_V731_V0.5010.34
66_A256_R0.5010.34
112_V116_A0.5010.34
80_S154_T0.5010.34
194_P397_I0.5000.34
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1vbgA 2 0.9654 100 0.304 Contact Map
2x0sA 2 0.9867 100 0.306 Contact Map
1kblA 2 0.9734 100 0.306 Contact Map
2olsA 2 0.8936 100 0.311 Contact Map
2hwgA 2 0.6941 100 0.637 Contact Map
2wqdA 2 0.6955 100 0.649 Contact Map
2xz9A 2 0.383 100 0.77 Contact Map
4l9zA 5 0.3364 100 0.881 Contact Map
4roqA 5 0.3378 100 0.887 Contact Map
3qz6A 5 0.3045 100 0.888 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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