Q9HS86 - HALSA - GREMLIN Contacts

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Q9HS86 - Htr14 transducer

UniProt:	Q9HS86	Sequences: MNITQAYKRSLWWSMDMVGATGSVERKMLTAVGLQFLAAGGMAFLTVFTAGTVQLIGVGGMLALSVVAFYNTYLIAEADFVEPLVALEDAADDIAAGEFERADIPSSKRDDEIASLVASFDGMQSNLEVASRQADALARQAFDDPALDESVPGAFGESITEMADSLEAYTAELEDKTAELEHQQAELERQSEQLRALVDALSEATDAARAGDLTATVDAAALDVTDDHRAAVEDFNQLLETLADTISDIQSFSDAVLAVSRTTDERVDAVADRSAAVSESVTEIADGANQQTNQLNNIAAEMDTVSATVEEIAASANDVAKTAQAAADRGEDGRGEVEETIEALRALREQSQAVAETVESLAAEVERIDGITALIEDIAEETNMLALNASIEAARTGSDGDGFAVVADEVKDLAEETREQAADISEIVDAVTEKAEDASIAIGEVDAEVERKITKAEGVLRDFEAIVDEVANVNHAVQEISDATDQGAQSVTDVVGMVEEVASVSEETAAESDTVADNAAEQTDATDEVADQMDELAEQTAALAGMLDDFTVPADAGTADQSVADDSPTAQPPAADDEPAAAVVDQPQPASDAEDEEGVPDSGGESVAVSDGGWADDRSSFTWADSQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	627 (495)
Sequences:	3522 (3207)
Seq/√Len:	144.2

ECOLI - AER MCP2 MCP4 MCP3 MCP1
BACSU - YVAQ TLPA TLPB MCPB YOAH MCPC MCPA TLPC HEMAT
HALSA - Q9HS86 HTR2 Q9HRA1 Q9HRN6 HTR4 Q9HP10 Q9HR88 COST HTR1 Q9HQX8 Q9HPA2 Q9HPQ5 HTR7 HTR9 HMAT Q9HQT5 Q9HPW6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
207_A	212_D	5.549	1.00
287_G	504_V	5.208	1.00
224_V	229_R	4.917	1.00
347_L	452_K	3.631	1.00
53_V	56_I	3.385	1.00
408_D	411_K	3.044	1.00
376_E	421_A	3.027	1.00
191_S	195_R	2.956	1.00
390_S	408_D	2.923	1.00
216_T	243_A	2.901	1.00
226_D	229_R	2.801	1.00
390_S	411_K	2.787	1.00
201_L	235_F	2.611	1.00
513_D	517_D	2.582	1.00
363_A	366_E	2.575	1.00
357_T	438_A	2.557	1.00
216_T	236_N	2.488	1.00
328_D	332_D	2.464	1.00
521_E	524_D	2.449	1.00
374_L	420_Q	2.430	1.00
77_E	80_F	2.422	1.00
261_R	265_E	2.387	1.00
520_A	524_D	2.333	1.00
364_E	434_K	2.328	1.00
510_A	514_T	2.328	1.00
364_E	430_A	2.326	1.00
192_E	196_A	2.264	1.00
329_R	465_A	2.260	1.00
341_I	460_L	2.258	1.00
208_A	239_L	2.246	1.00
205_T	235_F	2.210	1.00
213_L	242_L	2.204	1.00
258_A	262_T	2.166	1.00
69_F	73_Y	2.121	1.00
360_S	434_K	2.094	1.00
411_K	415_E	2.073	1.00
482_D	485_D	2.054	1.00
208_A	238_L	2.053	1.00
344_L	452_K	2.046	1.00
417_T	421_A	2.043	1.00
236_N	239_L	2.038	1.00
56_I	61_M	2.031	1.00
205_T	234_D	2.023	1.00
219_A	224_V	1.988	1.00
367_R	370_G	1.983	1.00
258_A	261_R	1.949	1.00
202_S	230_A	1.928	1.00
265_E	268_D	1.924	1.00
416_E	419_E	1.918	1.00
71_N	75_I	1.912	1.00
371_I	428_V	1.905	1.00
216_T	240_E	1.889	1.00
206_D	230_A	1.886	1.00
280_S	511_E	1.873	1.00
482_D	486_Q	1.871	1.00
205_T	238_L	1.866	1.00
258_A	265_E	1.819	1.00
346_A	448_E	1.804	1.00
305_V	487_G	1.803	1.00
364_E	367_R	1.783	1.00
517_D	520_A	1.781	1.00
344_L	347_L	1.763	1.00
485_D	489_Q	1.762	1.00
510_A	513_D	1.743	1.00
248_D	542_A	1.740	1.00
219_A	236_N	1.736	1.00
362_A	439_S	1.724	1.00
503_S	507_E	1.721	1.00
340_T	456_A	1.709	1.00
205_T	208_A	1.703	1.00
216_T	239_L	1.701	1.00
365_V	435_A	1.699	1.00
506_E	510_A	1.674	1.00
80_F	84_L	1.671	1.00
371_I	427_I	1.670	1.00
202_S	234_D	1.661	1.00
414_A	417_T	1.647	1.00
197_L	228_H	1.645	1.00
369_D	432_T	1.640	1.00
187_L	191_S	1.635	1.00
265_E	269_A	1.613	1.00
482_D	489_Q	1.598	1.00
205_T	231_A	1.586	1.00
373_A	377_D	1.586	1.00
269_A	272_D	1.577	1.00
215_A	239_L	1.570	1.00
333_G	466_I	1.562	1.00
367_R	423_D	1.552	1.00
304_T	307_A	1.546	1.00
330_G	467_V	1.543	1.00
207_A	215_A	1.541	1.00
517_D	524_D	1.537	1.00
358_V	439_S	1.530	1.00
340_T	459_V	1.516	1.00
351_S	449_V	1.514	1.00
332_D	335_G	1.513	1.00
206_D	234_D	1.509	1.00
447_A	450_E	1.495	1.00
137_L	142_F	1.493	1.00
463_F	466_I	1.487	1.00
77_E	81_V	1.476	1.00
283_E	286_D	1.475	1.00
386_A	411_K	1.475	1.00
76_A	80_F	1.474	1.00
457_E	461_R	1.474	1.00
295_L	501_V	1.473	1.00
298_I	494_V	1.468	1.00
194_L	198_V	1.458	1.00
138_A	142_F	1.453	1.00
472_N	475_H	1.453	1.00
458_G	461_R	1.450	1.00
212_D	215_A	1.446	1.00
91_A	94_I	1.445	1.00
306_S	495_V	1.444	1.00
486_Q	489_Q	1.442	1.00
260_S	533_M	1.440	1.00
418_R	422_A	1.432	1.00
287_G	508_T	1.432	1.00
282_T	286_D	1.431	1.00
527_D	531_D	1.429	1.00
235_F	238_L	1.421	1.00
351_S	354_V	1.419	1.00
217_V	232_V	1.407	1.00
162_M	166_L	1.405	1.00
361_L	431_V	1.400	1.00
285_A	288_A	1.393	1.00
358_V	438_A	1.391	1.00
380_E	418_R	1.388	1.00
323_A	473_V	1.387	1.00
386_A	415_E	1.383	1.00
333_G	463_F	1.382	1.00
294_Q	297_N	1.369	1.00
325_A	328_D	1.367	1.00
538_E	542_A	1.366	1.00
507_E	510_A	1.362	1.00
73_Y	77_E	1.362	1.00
297_N	300_A	1.352	1.00
381_E	409_E	1.345	1.00
303_D	307_A	1.341	1.00
399_D	410_V	1.341	1.00
198_V	231_A	1.318	1.00
56_I	68_A	1.317	1.00
519_A	523_T	1.316	1.00
56_I	70_Y	1.313	1.00
386_A	410_V	1.312	1.00
208_A	235_F	1.310	1.00
204_A	235_F	1.301	1.00
272_D	275_A	1.296	1.00
535_E	538_E	1.288	1.00
492_T	496_G	1.287	1.00
387_L	395_R	1.283	1.00
528_E	531_D	1.277	1.00
262_T	265_E	1.277	1.00
268_D	272_D	1.275	1.00
188_E	192_E	1.274	1.00
329_R	469_E	1.271	1.00
336_E	458_G	1.269	1.00
326_A	470_V	1.265	1.00
231_A	235_F	1.264	1.00
243_A	247_S	1.255	1.00
208_A	213_L	1.235	1.00
311_E	314_A	1.235	1.00
449_V	452_K	1.234	1.00
359_E	443_G	1.225	1.00
349_E	353_A	1.219	1.00
293_N	297_N	1.219	1.00
323_A	477_V	1.219	1.00
281_V	515_V	1.213	1.00
318_D	476_A	1.212	1.00
58_V	65_S	1.212	1.00
173_L	180_L	1.211	1.00
121_D	125_S	1.209	1.00
454_T	458_G	1.207	1.00
461_R	465_A	1.204	1.00
517_D	521_E	1.202	1.00
197_L	227_D	1.187	1.00
360_S	363_A	1.185	1.00
524_D	528_E	1.181	1.00
511_E	514_T	1.180	1.00
383_N	411_K	1.172	1.00
447_A	451_R	1.167	1.00
342_E	346_A	1.165	1.00
370_G	373_A	1.164	1.00
199_D	202_S	1.164	1.00
128_E	132_R	1.162	1.00
159_I	162_M	1.162	1.00
337_V	459_V	1.157	1.00
156_G	160_T	1.154	1.00
351_S	442_I	1.152	1.00
132_R	136_A	1.152	1.00
354_V	445_V	1.149	0.99
57_G	61_M	1.141	0.99
298_I	497_M	1.141	0.99
308_T	486_Q	1.134	0.99
272_D	276_A	1.133	0.99
202_S	206_D	1.123	0.99
321_K	325_A	1.119	0.99
410_V	415_E	1.118	0.99
310_E	314_A	1.116	0.99
113_I	117_V	1.114	0.99
357_T	437_D	1.113	0.99
343_A	451_R	1.109	0.99
372_T	424_I	1.109	0.99
212_D	551_T	1.105	0.99
503_S	506_E	1.105	0.99
58_V	62_L	1.102	0.99
450_E	454_T	1.100	0.99
217_V	236_N	1.098	0.99
149_E	153_G	1.097	0.99
59_G	65_S	1.091	0.99
198_V	228_H	1.091	0.99
276_A	279_E	1.089	0.99
177_T	181_E	1.086	0.99
295_L	302_M	1.079	0.99
164_D	168_A	1.078	0.99
197_L	224_V	1.072	0.99
479_E	482_D	1.072	0.99
300_A	303_D	1.071	0.99
510_A	517_D	1.070	0.99
110_D	114_A	1.066	0.99
372_T	425_S	1.064	0.99
500_E	503_S	1.064	0.99
423_D	426_E	1.064	0.99
288_A	508_T	1.061	0.99
281_V	284_I	1.060	0.99
185_A	189_R	1.054	0.99
133_Q	137_L	1.050	0.99
489_Q	493_D	1.050	0.99
324_Q	328_D	1.050	0.99
531_D	534_D	1.048	0.99
361_L	371_I	1.047	0.99
465_A	468_D	1.047	0.99
290_Q	293_N	1.047	0.99
285_A	509_A	1.047	0.99
213_L	235_F	1.046	0.99
419_E	423_D	1.038	0.99
367_R	427_I	1.035	0.99
56_I	226_D	1.034	0.99
64_L	68_A	1.027	0.99
204_A	217_V	1.024	0.99
312_I	484_T	1.021	0.99
120_F	123_M	1.018	0.99
545_G	548_D	1.016	0.99
114_A	118_A	1.014	0.99
248_D	546_M	1.013	0.99
70_Y	74_L	1.006	0.99
448_E	451_R	1.005	0.99
334_R	338_E	1.000	0.99
132_R	135_D	1.000	0.99
55_L	61_M	0.996	0.99
438_A	445_V	0.994	0.99
313_A	316_A	0.994	0.99
278_S	516_A	0.991	0.98
456_A	460_L	0.991	0.98
239_L	243_A	0.988	0.98
197_L	235_F	0.987	0.98
358_V	442_I	0.986	0.98
438_A	442_I	0.984	0.98
370_G	374_L	0.984	0.98
327_A	331_E	0.982	0.98
219_A	232_V	0.981	0.98
438_A	441_A	0.981	0.98
159_I	163_A	0.979	0.98
305_V	491_V	0.977	0.98
543_L	550_F	0.974	0.98
338_E	342_E	0.974	0.98
138_A	141_A	0.974	0.98
302_M	494_V	0.974	0.98
314_A	318_D	0.972	0.98
135_D	138_A	0.969	0.98
461_R	464_E	0.967	0.98
61_M	68_A	0.967	0.98
319_V	473_V	0.964	0.98
191_S	194_L	0.963	0.98
175_D	179_E	0.962	0.98
298_I	498_V	0.962	0.98
125_S	128_E	0.961	0.98
355_A	442_I	0.958	0.98
55_L	58_V	0.956	0.98
78_A	82_E	0.954	0.98
522_Q	536_L	0.946	0.98
195_R	228_H	0.943	0.98
285_A	517_D	0.942	0.98
359_E	363_A	0.940	0.98
180_L	184_Q	0.940	0.98
292_T	502_A	0.938	0.98
205_T	217_V	0.935	0.98
491_V	495_V	0.934	0.98
347_L	449_V	0.933	0.98
175_D	178_A	0.931	0.98
365_V	371_I	0.930	0.98
204_A	207_A	0.930	0.98
463_F	536_L	0.929	0.98
524_D	531_D	0.928	0.98
59_G	62_L	0.928	0.98
270_V	274_S	0.928	0.98
330_G	334_R	0.927	0.98
260_S	540_T	0.926	0.98
173_L	177_T	0.925	0.98
274_S	522_Q	0.922	0.98
146_A	150_S	0.922	0.98
348_R	453_I	0.914	0.97
249_I	547_L	0.913	0.97
208_A	217_V	0.912	0.97
404_A	410_V	0.912	0.97
189_R	192_E	0.910	0.97
193_Q	197_L	0.910	0.97
306_S	491_V	0.909	0.97
155_F	162_M	0.909	0.97
291_Q	505_S	0.909	0.97
524_D	527_D	0.908	0.97
412_D	415_E	0.908	0.97
108_K	112_E	0.907	0.97
371_I	420_Q	0.906	0.97
285_A	516_A	0.906	0.97
346_A	349_E	0.902	0.97
275_A	279_E	0.902	0.97
384_M	394_A	0.898	0.97
54_Q	226_D	0.897	0.97
308_T	483_A	0.896	0.97
340_T	452_K	0.896	0.97
54_Q	73_Y	0.892	0.97
129_V	132_R	0.892	0.97
140_Q	143_D	0.889	0.97
307_A	311_E	0.888	0.97
270_V	526_T	0.888	0.97
112_E	115_S	0.888	0.97
152_P	156_G	0.887	0.97
178_A	181_E	0.885	0.97
326_A	473_V	0.884	0.97
194_L	197_L	0.883	0.97
258_A	537_A	0.883	0.97
489_Q	492_T	0.881	0.97
206_D	210_A	0.880	0.97
422_A	426_E	0.880	0.97
370_G	423_D	0.880	0.97
264_D	269_A	0.879	0.97
207_A	210_A	0.879	0.97
131_S	135_D	0.879	0.97
167_E	170_T	0.877	0.97
361_L	438_A	0.875	0.97
310_E	492_T	0.872	0.97
201_L	231_A	0.871	0.97
344_L	456_A	0.870	0.97
80_F	83_P	0.869	0.97
317_N	321_K	0.869	0.97
195_R	198_V	0.866	0.96
121_D	124_Q	0.864	0.96
503_S	510_A	0.863	0.96
335_G	339_E	0.862	0.96
55_L	59_G	0.860	0.96
342_E	345_R	0.859	0.96
343_A	452_K	0.859	0.96
311_E	479_E	0.858	0.96
208_A	242_L	0.855	0.96
53_V	57_G	0.854	0.96
459_V	463_F	0.851	0.96
166_L	170_T	0.849	0.96
350_Q	448_E	0.842	0.96
445_V	452_K	0.841	0.96
134_A	140_Q	0.838	0.96
459_V	462_D	0.836	0.96
293_N	300_A	0.835	0.96
299_A	495_V	0.833	0.96
274_S	526_T	0.832	0.96
197_L	201_L	0.831	0.96
65_S	68_A	0.828	0.95
343_A	455_K	0.826	0.95
246_I	249_I	0.825	0.95
155_F	158_S	0.824	0.95
295_L	498_V	0.823	0.95
204_A	208_A	0.821	0.95
177_T	180_L	0.821	0.95
251_S	254_D	0.818	0.95
371_I	421_A	0.818	0.95
203_E	207_A	0.814	0.95
472_N	476_A	0.812	0.95
304_T	490_S	0.811	0.95
294_Q	500_E	0.808	0.95
330_G	466_I	0.808	0.95
456_A	459_V	0.807	0.95
201_L	228_H	0.805	0.95
514_T	517_D	0.804	0.95
331_E	335_G	0.803	0.95
187_L	194_L	0.803	0.95
131_S	134_A	0.802	0.95
113_I	116_L	0.802	0.95
170_T	173_L	0.802	0.95
138_A	143_D	0.802	0.95
91_A	95_A	0.800	0.94
397_G	400_G	0.799	0.94
160_T	164_D	0.799	0.94
337_V	456_A	0.799	0.94
209_R	234_D	0.798	0.94
417_T	427_I	0.796	0.94
356_E	360_S	0.793	0.94
241_T	244_D	0.793	0.94
111_D	115_S	0.791	0.94
467_V	471_A	0.791	0.94
250_Q	254_D	0.790	0.94
211_G	238_L	0.789	0.94
260_S	263_T	0.788	0.94
309_V	491_V	0.787	0.94
263_T	267_V	0.786	0.94
206_D	209_R	0.786	0.94
241_T	549_D	0.785	0.94
355_A	446_D	0.785	0.94
540_T	543_L	0.784	0.94
278_S	517_D	0.784	0.94
129_V	133_Q	0.781	0.94
205_T	239_L	0.777	0.94
276_A	514_T	0.777	0.94
343_A	448_E	0.777	0.94
340_T	460_L	0.776	0.94
363_A	367_R	0.770	0.93
54_Q	57_G	0.768	0.93
334_R	464_E	0.766	0.93
269_A	524_D	0.763	0.93
254_D	258_A	0.763	0.93
362_A	435_A	0.763	0.93
111_D	114_A	0.762	0.93
123_M	127_L	0.762	0.93
225_T	229_R	0.762	0.93
515_V	522_Q	0.762	0.93
371_I	374_L	0.761	0.93
236_N	240_E	0.759	0.93
89_D	93_D	0.759	0.93
96_A	100_E	0.759	0.93
493_D	496_G	0.759	0.93
191_S	197_L	0.758	0.93
174_E	180_L	0.756	0.93
211_G	236_N	0.756	0.93
305_V	309_V	0.753	0.93
289_N	513_D	0.752	0.92
357_T	441_A	0.752	0.92
314_A	317_N	0.749	0.92
56_I	59_G	0.749	0.92
161_E	165_S	0.749	0.92
292_T	506_E	0.746	0.92
358_V	361_L	0.746	0.92
150_S	154_A	0.745	0.92
86_A	90_A	0.744	0.92
277_V	515_V	0.744	0.92
357_T	434_K	0.741	0.92
463_F	473_V	0.741	0.92
208_A	211_G	0.740	0.92
534_D	538_E	0.740	0.92
296_N	300_A	0.739	0.92
224_V	232_V	0.736	0.92
279_E	282_T	0.735	0.92
516_A	520_A	0.735	0.92
546_M	549_D	0.735	0.92
205_T	236_N	0.735	0.92
355_A	438_A	0.734	0.92
291_Q	504_V	0.734	0.92
280_S	518_N	0.733	0.92
230_A	233_E	0.729	0.91
115_S	119_S	0.729	0.91
536_L	540_T	0.727	0.91
341_I	456_A	0.726	0.91
440_I	444_E	0.726	0.91
401_D	408_D	0.726	0.91
245_T	249_I	0.725	0.91
295_L	502_A	0.723	0.91
214_T	551_T	0.722	0.91
507_E	511_E	0.721	0.91
55_L	68_A	0.720	0.91
160_T	163_A	0.720	0.91
210_A	237_Q	0.720	0.91
398_S	401_D	0.719	0.91
69_F	72_T	0.719	0.91
323_A	330_G	0.718	0.91
415_E	419_E	0.716	0.91
157_E	161_E	0.714	0.90
88_E	92_D	0.714	0.90
158_S	165_S	0.714	0.90
432_T	435_A	0.713	0.90
139_R	143_D	0.713	0.90
246_I	552_V	0.711	0.90
376_E	425_S	0.710	0.90
436_E	440_I	0.709	0.90
289_N	293_N	0.707	0.90
312_I	483_A	0.707	0.90
319_V	326_A	0.705	0.90
147_L	150_S	0.705	0.90
176_K	180_L	0.703	0.90
361_L	435_A	0.702	0.90
379_A	418_R	0.701	0.90
286_D	289_N	0.698	0.89
213_L	246_I	0.694	0.89
176_K	181_E	0.694	0.89
315_S	479_E	0.693	0.89
331_E	471_A	0.693	0.89
168_A	172_E	0.692	0.89
348_R	450_E	0.692	0.89
109_R	114_A	0.691	0.89
390_S	410_V	0.691	0.89
113_I	120_F	0.691	0.89
302_M	498_V	0.691	0.89
378_I	417_T	0.691	0.89
202_S	228_H	0.690	0.89
313_A	481_S	0.688	0.89
525_A	529_V	0.688	0.89
366_E	436_E	0.687	0.89
545_G	549_D	0.687	0.89
200_A	219_A	0.686	0.89
74_L	78_A	0.685	0.89
56_I	77_E	0.682	0.88
66_V	69_F	0.682	0.88
354_V	361_L	0.681	0.88
484_T	487_G	0.680	0.88
89_D	92_D	0.676	0.88
279_E	283_E	0.675	0.88
325_A	465_A	0.675	0.88
463_F	487_G	0.675	0.88
305_V	417_T	0.673	0.88
267_V	526_T	0.671	0.87
173_L	176_K	0.670	0.87
499_E	503_S	0.670	0.87
171_A	174_E	0.668	0.87
339_E	451_R	0.666	0.87
156_G	163_A	0.665	0.87
437_D	440_I	0.664	0.87
145_P	149_E	0.664	0.87
244_D	248_D	0.662	0.87
340_T	491_V	0.660	0.87
153_G	157_E	0.659	0.87
278_S	520_A	0.657	0.86
232_V	236_N	0.657	0.86
486_Q	493_D	0.657	0.86
422_A	425_S	0.656	0.86
98_E	101_R	0.655	0.86
384_M	412_D	0.654	0.86
109_R	117_V	0.654	0.86
53_V	64_L	0.651	0.86
297_N	493_D	0.651	0.86
175_D	181_E	0.649	0.86
156_G	159_I	0.649	0.86
204_A	239_L	0.648	0.86
157_E	160_T	0.648	0.86
285_A	513_D	0.647	0.86
162_M	170_T	0.647	0.86
56_I	67_V	0.647	0.86
56_I	60_G	0.647	0.86
197_L	229_R	0.646	0.85
365_V	452_K	0.646	0.85
347_L	448_E	0.646	0.85
351_S	355_A	0.642	0.85
123_M	126_N	0.642	0.85
134_A	138_A	0.642	0.85
364_E	431_V	0.641	0.85
155_F	166_L	0.640	0.85
195_R	202_S	0.639	0.85
190_Q	193_Q	0.639	0.85
131_S	137_L	0.639	0.85
410_V	416_E	0.638	0.85
343_A	347_L	0.638	0.85
77_E	84_L	0.637	0.85
419_E	422_A	0.631	0.84
57_G	62_L	0.630	0.84
263_T	533_M	0.630	0.84
353_A	356_E	0.630	0.84
509_A	513_D	0.629	0.84
238_L	245_T	0.629	0.84
174_E	178_A	0.629	0.84
321_K	324_Q	0.629	0.84
171_A	175_D	0.628	0.84
280_S	515_V	0.625	0.84
86_A	89_D	0.625	0.84
301_E	493_D	0.624	0.83
306_S	488_A	0.623	0.83
134_A	137_L	0.622	0.83
117_V	120_F	0.621	0.83
109_R	112_E	0.621	0.83
255_A	535_E	0.620	0.83
456_A	466_I	0.619	0.83
334_R	467_V	0.618	0.83
516_A	519_A	0.618	0.83
332_D	465_A	0.618	0.83
79_D	83_P	0.617	0.83
520_A	528_E	0.616	0.83
137_L	140_Q	0.615	0.83
333_G	337_V	0.614	0.82
318_D	321_K	0.614	0.82
536_L	550_F	0.614	0.82
88_E	91_A	0.611	0.82
201_L	236_N	0.610	0.82
544_A	548_D	0.609	0.82
135_D	139_R	0.608	0.82
440_I	443_G	0.607	0.82
257_L	261_R	0.606	0.82
171_A	176_K	0.605	0.82
144_D	147_L	0.605	0.82
541_A	545_G	0.604	0.81
383_N	415_E	0.602	0.81
159_I	165_S	0.601	0.81
188_E	226_D	0.600	0.81
170_T	176_K	0.598	0.81
365_V	372_T	0.598	0.81
302_M	305_V	0.597	0.81
335_G	338_E	0.597	0.81
195_R	199_D	0.597	0.81
480_I	487_G	0.596	0.81
273_R	521_E	0.595	0.80
526_T	536_L	0.594	0.80
134_A	142_F	0.592	0.80
167_E	171_A	0.592	0.80
113_I	119_S	0.592	0.80
111_D	141_A	0.591	0.80
431_V	435_A	0.590	0.80
200_A	218_D	0.590	0.80
529_V	532_Q	0.589	0.80
291_Q	309_V	0.589	0.80
213_L	239_L	0.588	0.80
156_G	162_M	0.586	0.79
538_E	541_A	0.586	0.79
431_V	434_K	0.585	0.79
115_S	120_F	0.583	0.79
448_E	456_A	0.583	0.79
339_E	458_G	0.582	0.79
362_A	436_E	0.581	0.79
174_E	181_E	0.579	0.79
116_L	119_S	0.579	0.79
454_T	457_E	0.579	0.79
371_I	376_E	0.579	0.79
351_S	445_V	0.579	0.79
496_G	499_E	0.578	0.79
300_A	304_T	0.577	0.78
206_D	237_Q	0.577	0.78
126_N	129_V	0.576	0.78
108_K	111_D	0.575	0.78
531_D	535_E	0.573	0.78
355_A	443_G	0.571	0.78
176_K	183_Q	0.571	0.78
178_A	184_Q	0.570	0.78
287_G	507_E	0.569	0.77
176_K	179_E	0.568	0.77
273_R	533_M	0.568	0.77
471_A	475_H	0.568	0.77
506_E	511_E	0.567	0.77
152_P	155_F	0.566	0.77
466_I	470_V	0.566	0.77
383_N	414_A	0.565	0.77
359_E	362_A	0.564	0.77
172_E	175_D	0.564	0.77
115_S	118_A	0.563	0.77
350_Q	444_E	0.563	0.77
234_D	241_T	0.563	0.77
354_V	442_I	0.563	0.77
135_D	140_Q	0.562	0.77
146_A	155_F	0.562	0.77
319_V	361_L	0.561	0.76
133_Q	138_A	0.561	0.76
178_A	182_H	0.561	0.76
224_V	236_N	0.559	0.76
456_A	515_V	0.559	0.76
343_A	346_A	0.558	0.76
58_V	61_M	0.558	0.76
287_G	291_Q	0.557	0.76
541_A	544_A	0.557	0.76
307_A	310_E	0.556	0.76
93_D	98_E	0.556	0.76
126_N	130_A	0.556	0.76
214_T	552_V	0.555	0.76
506_E	514_T	0.554	0.76
66_V	70_Y	0.553	0.75
204_A	215_A	0.553	0.75
301_E	490_S	0.552	0.75
256_V	536_L	0.552	0.75
368_I	431_V	0.552	0.75
371_I	463_F	0.551	0.75
347_L	350_Q	0.551	0.75
390_S	412_D	0.551	0.75
113_I	118_A	0.551	0.75
304_T	308_T	0.549	0.75
154_A	158_S	0.549	0.75
435_A	438_A	0.547	0.75
87_L	90_A	0.546	0.75
377_D	380_E	0.545	0.74
282_T	516_A	0.543	0.74
277_V	518_N	0.543	0.74
205_T	209_R	0.542	0.74
536_L	543_L	0.541	0.74
81_V	84_L	0.540	0.74
432_T	436_E	0.540	0.74
56_I	73_Y	0.538	0.73
288_A	512_S	0.538	0.73
163_A	166_L	0.537	0.73
171_A	177_T	0.537	0.73
502_A	506_E	0.535	0.73
417_T	459_V	0.535	0.73
103_D	114_A	0.534	0.73
179_E	183_Q	0.534	0.73
328_D	331_E	0.534	0.73
65_S	81_V	0.534	0.73
181_E	184_Q	0.533	0.73
448_E	452_K	0.533	0.73
330_G	340_T	0.531	0.73
368_I	427_I	0.530	0.72
238_L	522_Q	0.528	0.72
298_I	305_V	0.527	0.72
72_T	79_D	0.527	0.72
354_V	438_A	0.526	0.72
137_L	141_A	0.525	0.72
333_G	522_Q	0.525	0.72
345_R	349_E	0.525	0.72
175_D	180_L	0.523	0.71
228_H	232_V	0.523	0.71
174_E	177_T	0.522	0.71
301_E	497_M	0.522	0.71
361_L	501_V	0.521	0.71
313_A	484_T	0.521	0.71
408_D	412_D	0.521	0.71
197_L	231_A	0.519	0.71
274_S	427_I	0.518	0.71
202_S	205_T	0.517	0.71
338_E	464_E	0.517	0.71
332_D	462_D	0.517	0.71
352_Q	446_D	0.516	0.70
286_D	290_Q	0.516	0.70
421_A	442_I	0.516	0.70
213_L	231_A	0.516	0.70
293_N	296_N	0.516	0.70
213_L	238_L	0.514	0.70
358_V	431_V	0.514	0.70
256_V	539_Q	0.513	0.70
294_Q	504_V	0.513	0.70
64_L	71_N	0.510	0.69
83_P	112_E	0.510	0.69
179_E	182_H	0.509	0.69
128_E	131_S	0.507	0.69
288_A	505_S	0.507	0.69
133_Q	142_F	0.506	0.69
280_S	284_I	0.505	0.69
312_I	487_G	0.504	0.69
195_R	227_D	0.504	0.69
134_A	141_A	0.504	0.69
533_M	536_L	0.503	0.68
442_I	460_L	0.503	0.68
226_D	232_V	0.502	0.68
260_S	536_L	0.501	0.68
132_R	138_A	0.500	0.68

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3zx6A	2	0.4848	100	0.436	Contact Map
2ch7A	2	0.4928	100	0.532	Contact Map
1qu7A	2	0.362	100	0.557	Contact Map
3g67A	2	0.3333	100	0.631	Contact Map
4i3mA	2	0.2344	99.9	0.781	Contact Map
3zccA	2	0.1738	98.9	0.894	Contact Map
4cq4A	4	0.1212	98.5	0.907	Contact Map
2f95B	2	0.0845	98.3	0.911	Contact Map
2rm8A	1	0.1085	98.3	0.911	Contact Map
4gycB	2	0.0973	98	0.918	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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