TRPE2 - HALSA - GREMLIN Contacts

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TRPE2 - Anthranilate synthase component 1 2

UniProt:	Q9HS66	Sequences: MPDSAALATDPAAFRDAAGDATAPTRAVVEARLPVTDPFAAYRRARGDAPSFHYETTGGSDGWGYFGVDPASMLRADGAGALDTVQAAVGARLARVGCDVPHPGGLFGWLSYDIARELEAIPDTTTDARGLPRLQLGVYPTIAAWREPFTPGDDLRLIAAVPVDEYTPDGAFEAGRDRVQSLAAAIRDGDPAVGPPPADSPAPFESVAGRAAFESRVRRIQDAIRDGDTFQANVSHRLDAPAAVHPVAVFEALRDTNPAPYSGIVEFPGVDLVSASPELLLARRGRELTTEPIAGTRPRGATPAEDDAARAALRADDKERAEHAMLVDLERNDLGKVSEYGSVAVPDYRRVDAYSEVLHLVSEVTGRLRDSCSLRDAIAAVFPGGTITGAPKPRTMALIDTVEATRRGPYTGSLAAIGFDGDATLSITIRTLVRRAATYHLRVGAGIVHDSTPAAEYDETLAKARALVTALGDAGGIGRVADTTPDNS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	488 (435)
Sequences:	5598 (3766)
Seq/√Len:	180.6

ECOLI - TRPE PABB MENF ENTC
BACSU - TRPE PABB MENF DHBC
HALSA - TRPE2 TRPE1 Q9HQN2
SULSO - TRPE

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
338_S	366_G	4.543	1.00
86_Q	373_S	4.135	1.00
339_E	367_R	4.107	1.00
387_I	411_T	4.043	1.00
210_R	214_E	3.677	1.00
339_E	370_D	3.415	1.00
297_R	312_A	3.313	1.00
287_E	365_T	3.246	1.00
239_D	438_T	3.022	1.00
296_T	357_V	3.019	1.00
452_T	455_A	2.970	1.00
346_P	365_T	2.961	1.00
223_A	228_D	2.811	1.00
214_E	454_A	2.727	1.00
223_A	401_T	2.690	1.00
347_D	350_R	2.690	1.00
210_R	454_A	2.586	1.00
213_F	445_A	2.577	1.00
209_G	212_A	2.568	1.00
394_R	397_A	2.535	1.00
415_A	425_L	2.435	1.00
80_G	83_D	2.430	1.00
299_R	306_D	2.399	1.00
52_F	67_G	2.391	1.00
372_C	376_D	2.389	1.00
307_D	311_A	2.380	1.00
222_D	226_D	2.378	1.00
344_A	365_T	2.376	1.00
311_A	315_A	2.371	1.00
369_R	372_C	2.312	1.00
310_R	353_A	2.311	1.00
80_G	379_A	2.273	1.00
239_D	440_H	2.244	1.00
246_P	271_D	2.229	1.00
241_P	438_T	2.228	1.00
208_A	216_R	2.223	1.00
286_R	367_R	2.185	1.00
229_T	232_A	2.169	1.00
112_Y	396_M	2.162	1.00
272_L	409_P	2.122	1.00
384_G	427_I	2.070	1.00
215_S	218_R	2.062	1.00
220_I	232_A	2.061	1.00
263_G	414_L	2.059	1.00
42_Y	51_S	2.012	1.00
62_G	146_R	1.998	1.00
351_V	360_L	1.993	1.00
287_E	367_R	1.986	1.00
300_G	305_E	1.947	1.00
263_G	274_S	1.928	1.00
307_D	310_R	1.921	1.00
353_A	358_L	1.905	1.00
316_D	319_E	1.901	1.00
65_Y	144_A	1.895	1.00
314_R	360_L	1.886	1.00
52_F	107_F	1.883	1.00
218_R	221_Q	1.838	1.00
337_V	380_A	1.832	1.00
43_R	251_E	1.832	1.00
303_P	307_D	1.817	1.00
334_L	338_S	1.810	1.00
273_V	434_R	1.795	1.00
290_T	330_E	1.782	1.00
434_R	439_Y	1.781	1.00
245_H	248_A	1.778	1.00
207_V	405_T	1.755	1.00
149_F	154_D	1.729	1.00
305_E	308_A	1.728	1.00
301_A	305_E	1.716	1.00
218_R	453_P	1.706	1.00
398_L	402_V	1.701	1.00
231_Q	446_G	1.696	1.00
222_D	225_R	1.694	1.00
279_L	424_T	1.669	1.00
41_A	145_W	1.660	1.00
300_G	309_A	1.659	1.00
220_I	234_V	1.654	1.00
454_A	458_D	1.653	1.00
293_I	361_V	1.639	1.00
310_R	351_V	1.621	1.00
339_E	369_R	1.616	1.00
291_E	352_D	1.602	1.00
210_R	457_Y	1.601	1.00
352_D	361_V	1.595	1.00
106_L	138_V	1.590	1.00
266_E	271_D	1.583	1.00
110_L	114_I	1.574	1.00
309_A	312_A	1.560	1.00
458_D	462_A	1.525	1.00
236_H	460_T	1.513	1.00
308_A	312_A	1.512	1.00
172_F	176_R	1.500	1.00
378_I	417_I	1.473	1.00
242_A	434_R	1.471	1.00
432_L	439_Y	1.457	1.00
284_R	422_D	1.454	1.00
141_T	178_R	1.452	1.00
302_T	305_E	1.451	1.00
409_P	428_T	1.445	1.00
234_V	445_A	1.424	1.00
217_V	453_P	1.417	1.00
214_E	218_R	1.400	1.00
55_E	254_R	1.388	1.00
219_R	401_T	1.380	1.00
223_A	394_R	1.374	1.00
210_R	458_D	1.372	1.00
204_F	240_A	1.372	1.00
237_R	440_H	1.361	1.00
113_D	400_D	1.356	1.00
335_G	341_G	1.352	1.00
223_A	398_L	1.348	1.00
41_A	186_I	1.348	1.00
219_R	222_D	1.346	1.00
81_A	134_L	1.345	1.00
229_T	395_T	1.334	1.00
86_Q	90_G	1.333	1.00
378_I	425_L	1.326	1.00
64_G	147_E	1.316	1.00
212_A	215_S	1.314	1.00
334_L	366_G	1.313	1.00
288_L	338_S	1.310	1.00
235_S	442_R	1.307	1.00
124_T	400_D	1.305	1.00
264_I	271_D	1.302	1.00
274_S	426_S	1.301	1.00
214_E	453_P	1.294	1.00
217_V	447_I	1.293	1.00
246_P	434_R	1.287	1.00
457_Y	461_L	1.285	1.00
249_V	434_R	1.280	1.00
127_D	130_G	1.280	1.00
416_A	424_T	1.278	1.00
443_V	464_A	1.275	1.00
455_A	458_D	1.273	1.00
113_D	406_R	1.272	1.00
289_T	365_T	1.265	1.00
212_A	404_A	1.260	1.00
84_T	87_A	1.256	1.00
234_V	447_I	1.252	1.00
304_A	308_A	1.239	1.00
211_A	215_S	1.237	1.00
38_P	145_W	1.236	1.00
205_E	241_P	1.235	1.00
418_G	422_D	1.234	1.00
291_E	347_D	1.221	1.00
263_G	272_L	1.220	1.00
241_P	437_A	1.219	1.00
414_L	428_T	1.214	1.00
458_D	461_L	1.212	1.00
394_R	401_T	1.212	1.00
368_L	377_A	1.205	1.00
346_P	363_E	1.199	1.00
36_T	44_R	1.197	1.00
432_L	467_L	1.185	1.00
288_L	334_L	1.185	1.00
233_N	444_G	1.183	1.00
46_R	266_E	1.173	1.00
283_R	377_A	1.173	1.00
240_A	439_Y	1.170	1.00
169_D	173_E	1.169	1.00
324_A	348_Y	1.167	1.00
249_V	432_L	1.166	1.00
232_A	399_I	1.164	1.00
144_A	158_I	1.161	1.00
283_R	288_L	1.161	1.00
219_R	223_A	1.158	1.00
375_R	417_I	1.157	1.00
86_Q	376_D	1.156	1.00
252_A	473_D	1.154	1.00
127_D	406_R	1.152	1.00
236_H	461_L	1.151	1.00
206_S	236_H	1.151	1.00
212_A	216_R	1.149	1.00
136_L	425_L	1.147	1.00
215_S	219_R	1.146	1.00
324_A	349_R	1.146	1.00
83_D	86_Q	1.142	1.00
445_A	460_T	1.135	1.00
283_R	368_L	1.135	1.00
286_R	370_D	1.133	1.00
225_R	449_H	1.132	1.00
261_Y	279_L	1.131	1.00
409_P	433_V	1.130	1.00
249_V	273_V	1.127	1.00
310_R	358_L	1.125	1.00
102_H	105_G	1.122	1.00
320_R	349_R	1.121	1.00
289_T	363_E	1.116	1.00
311_A	314_R	1.111	1.00
143_A	155_L	1.109	1.00
157_L	183_A	1.101	1.00
110_L	417_I	1.101	1.00
81_A	117_E	1.094	1.00
218_R	222_D	1.089	1.00
247_V	264_I	1.086	1.00
274_S	414_L	1.084	1.00
257_N	275_A	1.083	1.00
131_L	433_V	1.081	1.00
135_Q	267_F	1.081	1.00
246_P	264_I	1.079	1.00
308_A	311_A	1.075	1.00
71_A	140_P	1.062	1.00
157_L	179_V	1.054	1.00
242_A	249_V	1.051	1.00
145_W	155_L	1.051	1.00
441_L	468_V	1.043	1.00
294_A	386_T	1.042	1.00
75_R	135_Q	1.039	1.00
138_V	419_F	1.036	1.00
441_L	464_A	1.034	1.00
291_E	363_E	1.031	1.00
280_L	381_V	1.028	1.00
334_L	381_V	1.027	1.00
269_G	435_R	1.026	0.99
314_R	351_V	1.020	0.99
297_R	309_A	1.011	0.99
327_V	348_Y	1.009	0.99
232_A	398_L	1.004	0.99
250_F	254_R	1.003	0.99
294_A	323_H	1.002	0.99
71_A	138_V	0.999	0.99
257_N	356_E	0.998	0.99
179_V	183_A	0.994	0.99
157_L	182_L	0.993	0.99
205_E	239_D	0.993	0.99
70_P	139_Y	0.989	0.99
242_A	439_Y	0.985	0.99
305_E	309_A	0.984	0.99
221_Q	449_H	0.982	0.99
387_I	429_I	0.980	0.99
178_R	181_S	0.977	0.99
55_E	250_F	0.977	0.99
83_D	87_A	0.975	0.99
80_G	117_E	0.975	0.99
86_Q	379_A	0.974	0.99
326_L	386_T	0.974	0.99
228_D	394_R	0.973	0.99
280_L	290_T	0.970	0.99
236_H	457_Y	0.965	0.99
465_R	469_T	0.962	0.99
65_Y	142_I	0.959	0.99
204_F	468_V	0.956	0.99
141_T	159_A	0.953	0.99
339_E	342_S	0.953	0.99
116_R	400_D	0.948	0.99
413_S	425_L	0.947	0.99
90_G	373_S	0.946	0.99
67_G	107_F	0.945	0.99
288_L	377_A	0.944	0.99
316_D	455_A	0.940	0.99
121_I	397_A	0.940	0.99
129_R	440_H	0.934	0.99
37_D	40_A	0.934	0.99
221_Q	225_R	0.933	0.99
69_D	141_T	0.932	0.99
298_P	462_A	0.931	0.99
294_A	326_L	0.930	0.99
220_I	402_V	0.926	0.99
298_P	309_A	0.925	0.99
119_E	393_P	0.925	0.99
208_A	404_A	0.920	0.99
101_P	284_R	0.918	0.99
220_I	447_I	0.915	0.99
122_P	397_A	0.913	0.99
400_D	406_R	0.912	0.99
110_L	136_L	0.912	0.99
128_A	405_T	0.908	0.99
88_A	91_A	0.907	0.99
109_W	409_P	0.906	0.99
233_N	387_I	0.906	0.99
211_A	214_E	0.905	0.99
457_Y	460_T	0.903	0.99
63_W	144_A	0.902	0.99
72_S	88_A	0.896	0.99
297_R	319_E	0.894	0.99
262_S	275_A	0.891	0.99
347_D	363_E	0.888	0.99
323_H	326_L	0.887	0.99
272_L	414_L	0.886	0.99
102_H	107_F	0.886	0.99
184_A	188_D	0.883	0.98
271_D	434_R	0.882	0.98
238_L	468_V	0.881	0.98
469_T	472_G	0.880	0.98
220_I	229_T	0.878	0.98
113_D	116_R	0.877	0.98
118_L	382_F	0.877	0.98
233_N	388_T	0.877	0.98
354_Y	361_V	0.872	0.98
176_R	180_Q	0.871	0.98
233_N	411_T	0.869	0.98
183_A	187_R	0.865	0.98
238_L	461_L	0.865	0.98
52_F	139_Y	0.864	0.98
62_G	148_P	0.864	0.98
73_M	135_Q	0.863	0.98
173_E	177_D	0.859	0.98
82_L	114_I	0.856	0.98
468_V	472_G	0.856	0.98
110_L	378_I	0.855	0.98
114_I	117_E	0.854	0.98
131_L	270_V	0.852	0.98
445_A	455_A	0.852	0.98
279_L	289_T	0.852	0.98
250_F	273_V	0.848	0.98
171_A	174_A	0.848	0.98
114_I	134_L	0.848	0.98
283_R	374_L	0.846	0.98
149_F	153_D	0.841	0.98
263_G	426_S	0.836	0.98
229_T	398_L	0.831	0.98
202_A	241_P	0.829	0.98
384_G	426_S	0.820	0.98
130_G	435_R	0.820	0.98
394_R	398_L	0.819	0.98
34_P	37_D	0.814	0.97
312_A	315_A	0.812	0.97
180_Q	183_A	0.808	0.97
111_S	133_R	0.807	0.97
297_R	462_A	0.804	0.97
207_V	239_D	0.800	0.97
290_T	381_V	0.800	0.97
374_L	423_A	0.799	0.97
286_R	339_E	0.797	0.97
283_R	286_R	0.796	0.97
116_R	123_D	0.793	0.97
107_F	265_V	0.792	0.97
259_A	262_S	0.792	0.97
85_V	136_L	0.791	0.97
214_E	217_V	0.787	0.97
51_S	266_E	0.786	0.97
217_V	221_Q	0.785	0.97
72_S	138_V	0.779	0.97
330_E	384_G	0.779	0.97
68_V	141_T	0.778	0.97
272_L	431_T	0.776	0.97
76_A	134_L	0.776	0.97
323_H	386_T	0.768	0.96
319_E	455_A	0.766	0.96
110_L	425_L	0.765	0.96
432_L	441_L	0.764	0.96
285_G	422_D	0.764	0.96
57_T	60_S	0.761	0.96
142_I	158_I	0.760	0.96
125_T	400_D	0.759	0.96
181_S	185_A	0.759	0.96
118_L	379_A	0.758	0.96
270_V	435_R	0.758	0.96
232_A	395_T	0.755	0.96
42_Y	264_I	0.754	0.96
335_G	340_Y	0.754	0.96
283_R	423_A	0.749	0.96
129_R	406_R	0.748	0.96
117_E	133_R	0.747	0.96
115_A	396_M	0.747	0.96
123_D	400_D	0.745	0.96
216_R	220_I	0.745	0.96
218_R	225_R	0.744	0.96
81_A	85_V	0.744	0.96
116_R	122_P	0.744	0.96
280_L	330_E	0.742	0.96
344_A	367_R	0.741	0.96
280_L	294_A	0.740	0.96
127_D	237_R	0.738	0.95
320_R	348_Y	0.737	0.95
265_V	414_L	0.737	0.95
282_A	289_T	0.736	0.95
110_L	134_L	0.734	0.95
214_E	452_T	0.733	0.95
417_I	423_A	0.733	0.95
398_L	401_T	0.730	0.95
34_P	39_F	0.726	0.95
256_T	469_T	0.724	0.95
177_D	180_Q	0.724	0.95
290_T	334_L	0.723	0.95
393_P	396_M	0.723	0.95
183_A	186_I	0.721	0.95
314_R	320_R	0.721	0.95
216_R	234_V	0.719	0.95
116_R	133_R	0.718	0.95
69_D	178_R	0.717	0.95
323_H	411_T	0.716	0.95
350_R	363_E	0.715	0.95
280_L	323_H	0.713	0.95
123_D	406_R	0.711	0.94
329_L	385_G	0.702	0.94
279_L	291_E	0.700	0.94
355_S	466_A	0.700	0.94
298_P	301_A	0.698	0.94
243_A	437_A	0.695	0.94
216_R	404_A	0.694	0.94
63_W	101_P	0.694	0.94
175_G	186_I	0.693	0.94
298_P	458_D	0.693	0.94
207_V	236_H	0.693	0.94
223_A	397_A	0.692	0.94
337_V	377_A	0.691	0.94
237_R	405_T	0.690	0.94
281_L	377_A	0.690	0.94
235_S	460_T	0.689	0.93
180_Q	184_A	0.687	0.93
206_S	460_T	0.686	0.93
387_I	427_I	0.685	0.93
173_E	219_R	0.682	0.93
208_A	212_A	0.681	0.93
119_E	336_K	0.681	0.93
267_F	270_V	0.680	0.93
42_Y	66_F	0.678	0.93
373_S	376_D	0.677	0.93
41_A	143_A	0.677	0.93
286_R	368_L	0.675	0.93
86_Q	375_R	0.674	0.93
135_Q	270_V	0.674	0.93
351_V	358_L	0.673	0.93
321_A	450_D	0.673	0.93
115_A	118_L	0.673	0.93
143_A	157_L	0.671	0.93
49_A	266_E	0.671	0.93
298_P	455_A	0.670	0.92
378_I	423_A	0.669	0.92
310_R	314_R	0.668	0.92
244_V	249_V	0.666	0.92
42_Y	46_R	0.666	0.92
435_R	438_T	0.665	0.92
393_P	397_A	0.665	0.92
39_F	251_E	0.665	0.92
323_H	358_L	0.663	0.92
259_A	356_E	0.660	0.92
208_A	236_H	0.659	0.92
281_L	381_V	0.659	0.92
110_L	415_A	0.657	0.92
328_D	331_R	0.655	0.92
50_P	73_M	0.655	0.92
33_L	37_D	0.654	0.92
249_V	439_Y	0.651	0.91
320_R	324_A	0.651	0.91
40_A	43_R	0.645	0.91
291_E	350_R	0.644	0.91
203_P	472_G	0.644	0.91
34_P	251_E	0.644	0.91
234_V	402_V	0.643	0.91
323_H	330_E	0.641	0.91
434_R	437_A	0.640	0.91
40_A	44_R	0.639	0.91
397_A	401_T	0.638	0.91
55_E	262_S	0.637	0.91
328_D	333_D	0.637	0.91
115_A	400_D	0.635	0.90
313_L	351_V	0.635	0.90
178_R	182_L	0.633	0.90
268_P	271_D	0.630	0.90
325_M	333_D	0.630	0.90
287_E	346_P	0.629	0.90
221_Q	453_P	0.629	0.90
272_L	428_T	0.628	0.90
71_A	419_F	0.627	0.90
125_T	128_A	0.625	0.90
235_S	444_G	0.624	0.90
131_L	409_P	0.623	0.90
323_H	327_V	0.623	0.90
224_I	449_H	0.623	0.90
127_D	435_R	0.622	0.89
258_P	355_S	0.621	0.89
36_T	40_A	0.619	0.89
182_L	186_I	0.619	0.89
103_P	420_D	0.618	0.89
103_P	418_G	0.617	0.89
233_N	274_S	0.616	0.89
247_V	251_E	0.616	0.89
43_R	247_V	0.615	0.89
386_T	445_A	0.615	0.89
469_T	473_D	0.612	0.89
342_S	367_R	0.612	0.89
92_R	95_R	0.611	0.89
347_D	352_D	0.611	0.89
233_N	426_S	0.610	0.89
321_A	325_M	0.610	0.89
461_L	465_R	0.608	0.88
405_T	442_R	0.608	0.88
345_V	348_Y	0.607	0.88
349_R	360_L	0.607	0.88
171_A	175_G	0.607	0.88
238_L	464_A	0.606	0.88
230_F	332_N	0.605	0.88
74_L	84_T	0.604	0.88
216_R	402_V	0.604	0.88
411_T	426_S	0.604	0.88
280_L	326_L	0.601	0.88
359_H	446_G	0.601	0.88
326_L	445_A	0.600	0.88
132_P	270_V	0.600	0.88
330_E	386_T	0.599	0.88
306_D	358_L	0.599	0.88
298_P	305_E	0.599	0.88
237_R	442_R	0.599	0.88
77_D	81_A	0.598	0.88
300_G	303_P	0.598	0.88
294_A	445_A	0.597	0.87
82_L	379_A	0.597	0.87
323_H	362_S	0.596	0.87
173_E	176_R	0.595	0.87
87_A	90_G	0.595	0.87
46_R	245_H	0.594	0.87
177_D	181_S	0.592	0.87
384_G	387_I	0.591	0.87
433_V	440_H	0.589	0.87
314_R	317_D	0.588	0.87
238_L	443_V	0.588	0.87
233_N	263_G	0.587	0.87
275_A	416_A	0.587	0.87
315_A	320_R	0.585	0.86
109_W	382_F	0.584	0.86
44_R	189_G	0.584	0.86
73_M	137_G	0.584	0.86
71_A	106_L	0.584	0.86
330_E	411_T	0.581	0.86
290_T	364_V	0.581	0.86
248_A	251_E	0.580	0.86
112_Y	388_T	0.580	0.86
172_F	175_G	0.580	0.86
46_R	49_A	0.578	0.86
42_Y	247_V	0.576	0.86
233_N	359_H	0.573	0.85
274_S	384_G	0.572	0.85
77_D	84_T	0.572	0.85
317_D	320_R	0.572	0.85
56_T	61_D	0.572	0.85
274_S	428_T	0.572	0.85
160_A	419_F	0.571	0.85
35_V	43_R	0.571	0.85
263_G	431_T	0.570	0.85
170_G	174_A	0.570	0.85
36_T	41_A	0.570	0.85
387_I	467_L	0.569	0.85
45_A	66_F	0.568	0.85
217_V	445_A	0.568	0.85
174_A	177_D	0.568	0.85
241_P	436_A	0.567	0.85
320_R	360_L	0.567	0.85
326_L	330_E	0.566	0.85
376_D	380_A	0.566	0.85
312_A	316_D	0.565	0.84
331_R	390_A	0.565	0.84
332_N	336_K	0.564	0.84
35_V	153_D	0.562	0.84
70_P	73_M	0.562	0.84
115_A	386_T	0.562	0.84
199_D	243_A	0.561	0.84
62_G	149_F	0.560	0.84
105_G	419_F	0.560	0.84
281_L	423_A	0.559	0.84
42_Y	53_H	0.559	0.84
274_S	411_T	0.558	0.84
231_Q	448_V	0.558	0.84
76_A	133_R	0.558	0.84
288_L	366_G	0.557	0.84
288_L	368_L	0.556	0.84
316_D	387_I	0.556	0.84
220_I	399_I	0.555	0.83
274_S	387_I	0.555	0.83
139_Y	142_I	0.555	0.83
297_R	358_L	0.554	0.83
404_A	442_R	0.554	0.83
161_V	175_G	0.553	0.83
381_V	425_L	0.551	0.83
461_L	468_V	0.551	0.83
240_A	471_L	0.551	0.83
294_A	448_V	0.551	0.83
462_A	465_R	0.550	0.83
249_V	471_L	0.550	0.83
215_S	222_D	0.550	0.83
330_E	426_S	0.549	0.83
386_T	442_R	0.548	0.83
227_G	331_R	0.548	0.83
338_S	343_V	0.548	0.83
220_I	398_L	0.547	0.83
328_D	390_A	0.547	0.83
213_F	460_T	0.547	0.83
209_G	214_E	0.546	0.82
304_A	307_D	0.546	0.82
130_G	196_P	0.545	0.82
258_P	275_A	0.544	0.82
228_D	332_N	0.543	0.82
384_G	411_T	0.542	0.82
302_T	308_A	0.541	0.82
319_E	386_T	0.539	0.82
291_E	354_Y	0.539	0.82
356_E	466_A	0.538	0.82
321_A	331_R	0.538	0.82
330_E	364_V	0.537	0.81
186_I	190_D	0.536	0.81
233_N	395_T	0.536	0.81
177_D	195_P	0.534	0.81
233_N	384_G	0.534	0.81
304_A	370_D	0.534	0.81
231_Q	326_L	0.534	0.81
125_T	404_A	0.532	0.81
170_G	173_E	0.532	0.81
136_L	415_A	0.531	0.81
309_A	358_L	0.531	0.81
65_Y	107_F	0.530	0.81
39_F	247_V	0.530	0.81
129_R	408_G	0.529	0.80
181_S	184_A	0.529	0.80
468_V	471_L	0.528	0.80
206_S	443_V	0.527	0.80
39_F	53_H	0.526	0.80
176_R	179_V	0.525	0.80
263_G	384_G	0.525	0.80
280_L	386_T	0.525	0.80
275_A	467_L	0.524	0.80
359_H	387_I	0.524	0.80
46_R	51_S	0.523	0.80
230_F	325_M	0.523	0.80
325_M	328_D	0.522	0.80
323_H	349_R	0.522	0.80
325_M	331_R	0.521	0.79
66_F	143_A	0.519	0.79
79_A	83_D	0.519	0.79
120_A	400_D	0.518	0.79
257_N	466_A	0.518	0.79
325_M	390_A	0.517	0.79
230_F	331_R	0.516	0.79
384_G	395_T	0.516	0.79
332_N	335_G	0.516	0.79
210_R	236_H	0.515	0.79
256_T	356_E	0.515	0.79
293_I	429_I	0.514	0.79
190_D	194_G	0.514	0.79
214_E	457_Y	0.513	0.78
110_L	382_F	0.513	0.78
292_P	329_L	0.512	0.78
233_N	330_E	0.511	0.78
76_A	117_E	0.509	0.78
31_A	34_P	0.509	0.78
196_P	243_A	0.508	0.78
120_A	397_A	0.506	0.77
82_L	118_L	0.506	0.77
230_F	333_D	0.506	0.77
76_A	81_A	0.506	0.77
221_Q	448_V	0.506	0.77
456_E	459_E	0.505	0.77
464_A	468_V	0.505	0.77
231_Q	359_H	0.504	0.77
133_R	406_R	0.504	0.77
284_R	287_E	0.504	0.77
367_R	370_D	0.503	0.77
104_G	418_G	0.503	0.77
115_A	326_L	0.503	0.77
234_V	444_G	0.502	0.77
78_G	86_Q	0.502	0.77
317_D	450_D	0.500	0.77

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1k0eA	1	0.8586	100	0.183	Contact Map
1qdlA	1	0.8463	100	0.191	Contact Map
1i1qA	2	0.9098	100	0.191	Contact Map
4grhA	1	0.8627	100	0.2	Contact Map
3logA	1	0.8811	100	0.231	Contact Map
3h9mA	1	0.7951	100	0.235	Contact Map
2fn0A	2	0.8053	100	0.274	Contact Map
3gseA	1	0.8463	100	0.301	Contact Map
3bzmA	1	0.8627	100	0.331	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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