SYP - HALSA - GREMLIN Contacts

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SYP - Proline--tRNA ligase

UniProt:	Q9HS52	Sequences: MSDDDQELGITESKEHSPGDWYAEVVQKAGLADYAPMGGFIVTRPRGYALWEAIQDNLDGWFKDTGVENAYFPMFIPEDYLEREKDIVEGFDPEVAWVTQGGHDDLDQRLAVRPTSESIIAPYLSQWVRSHRDLPLRVNQWNSVVRWEATETKPFFRTKEFLWQEGHTAHATDEAAWAETTLRLDQYHRLYEDVLGIPVLRGRKPDHDKFPGADTTMSVEALMPDGKSVQGGTSHHLGQSFADAFDITFADEDEAERTAYTTSWGLSWRAIGALVMSHSDDQGLVLPPTVAPKQVVIVPIWQEDTKDDVEQYGAEIAAELEAQGVRVHFDDRDGRNPGFKFNEWELNGVPVRFEIGPNEVEDDEVTVVHRPDGESTVEDRAAIADRVHDHLDEVYDKLYDAAADRLAENVREADNRADILGTIGQHGGYVKAPWCGDQDCEAEIKDQIAAEIVMVPLGEDSAARAASELEGERVPEPDHDGEDCAICGDEATRTAYFAKSY	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	501 (382)
Sequences:	3484 (1556)
Seq/√Len:	79.6

ECOLI - SYP SYT
BACSU - SYP SYT1 SYT2
HALSA - SYP SYT
SULSO - SYP SYT

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
251_D	257_R	5.920	1.00
30_G	44_R	3.417	1.00
312_Y	315_E	3.343	1.00
61_W	64_D	3.332	1.00
253_D	257_R	3.290	1.00
382_A	385_D	3.133	1.00
75_F	145_V	3.064	1.00
315_E	319_E	3.022	1.00
295_V	325_V	2.972	1.00
317_A	321_E	2.642	1.00
239_Q	260_Y	2.598	1.00
192_E	199_V	2.572	1.00
61_W	189_R	2.519	1.00
297_I	317_A	2.488	1.00
75_F	112_V	2.479	1.00
178_A	182_L	2.471	1.00
364_E	379_D	2.417	1.00
307_D	311_Q	2.411	1.00
171_A	252_E	2.375	1.00
15_E	281_D	2.356	1.00
68_E	328_H	2.324	1.00
189_R	193_D	2.322	1.00
319_E	384_A	2.318	1.00
386_R	389_D	2.309	1.00
332_R	343_E	2.302	1.00
171_A	249_F	2.286	1.00
56_D	60_G	2.277	1.00
364_E	377_V	2.238	1.00
248_T	256_E	2.232	1.00
170_H	175_A	2.220	1.00
309_V	357_P	2.219	1.00
177_W	236_H	2.212	1.00
296_V	344_W	2.201	1.00
294_Q	326_R	2.194	1.00
337_P	341_F	2.191	1.00
314_A	318_A	2.185	1.00
188_H	192_E	2.159	1.00
239_Q	243_D	2.147	1.00
317_A	329_F	2.117	1.00
78_E	109_R	2.104	1.00
52_E	55_Q	2.090	1.00
67_V	179_E	2.026	1.00
382_A	386_R	2.016	1.00
376_T	386_R	2.013	1.00
379_D	382_A	1.999	1.00
312_Y	360_V	1.996	1.00
216_T	219_V	1.983	1.00
275_V	284_L	1.902	1.00
170_H	179_E	1.892	1.00
53_A	326_R	1.875	1.00
236_H	260_Y	1.840	1.00
274_L	290_V	1.837	1.00
78_E	83_R	1.822	1.00
175_A	178_A	1.818	1.00
172_T	175_A	1.812	1.00
84_E	125_S	1.805	1.00
64_D	321_E	1.796	1.00
318_A	322_A	1.753	1.00
389_D	393_E	1.746	1.00
185_D	189_R	1.727	1.00
185_D	188_H	1.719	1.00
297_I	313_G	1.718	1.00
251_D	255_A	1.712	1.00
59_D	69_N	1.710	1.00
210_F	223_M	1.708	1.00
344_W	349_V	1.688	1.00
60_G	64_D	1.686	1.00
325_V	388_H	1.670	1.00
63_K	139_N	1.640	1.00
112_V	145_V	1.632	1.00
50_L	271_I	1.632	1.00
385_D	389_D	1.628	1.00
57_N	61_W	1.626	1.00
311_Q	315_E	1.622	1.00
363_D	381_A	1.615	1.00
351_V	387_V	1.612	1.00
323_Q	388_H	1.600	1.00
17_S	20_D	1.597	1.00
282_Q	342_N	1.593	1.00
46_R	347_N	1.586	1.00
52_E	63_K	1.584	1.00
366_T	377_V	1.583	1.00
70_A	120_I	1.578	1.00
169_A	259_A	1.570	1.00
317_A	327_V	1.545	0.99
388_H	392_D	1.544	0.99
78_E	82_E	1.529	0.99
308_D	361_E	1.521	0.99
177_W	181_T	1.518	0.99
67_V	137_R	1.511	0.99
314_A	329_F	1.503	0.99
314_A	331_D	1.486	0.99
313_G	329_F	1.475	0.99
121_A	247_I	1.467	0.99
188_H	201_R	1.464	0.99
311_Q	314_A	1.455	0.99
191_Y	219_V	1.446	0.99
35_A	40_F	1.442	0.99
358_N	362_D	1.431	0.99
293_K	328_H	1.425	0.99
26_V	155_F	1.414	0.99
357_P	361_E	1.391	0.99
319_E	380_R	1.389	0.99
358_N	361_E	1.376	0.99
319_E	381_A	1.372	0.99
121_A	261_T	1.368	0.99
351_V	367_V	1.363	0.99
52_E	69_N	1.363	0.99
188_H	199_V	1.360	0.99
383_I	387_V	1.353	0.99
314_A	317_A	1.325	0.98
206_D	209_K	1.323	0.98
312_Y	355_I	1.320	0.98
195_L	290_V	1.318	0.98
282_Q	373_G	1.300	0.98
58_L	62_F	1.299	0.98
297_I	316_I	1.297	0.98
58_L	190_L	1.273	0.98
248_T	258_T	1.258	0.98
173_D	177_W	1.256	0.98
369_H	372_D	1.255	0.98
59_D	63_K	1.249	0.98
70_A	138_V	1.249	0.98
75_F	98_V	1.245	0.98
219_V	231_G	1.244	0.97
249_F	257_R	1.243	0.97
82_E	86_D	1.237	0.97
297_I	355_I	1.232	0.97
61_W	65_T	1.226	0.97
99_T	109_R	1.223	0.97
353_F	367_V	1.222	0.97
392_D	396_D	1.203	0.97
60_G	193_D	1.198	0.97
183_R	186_Q	1.187	0.97
64_D	189_R	1.182	0.97
49_A	53_A	1.180	0.97
330_D	340_K	1.179	0.97
312_Y	380_R	1.174	0.96
14_K	224_P	1.173	0.96
26_V	31_L	1.172	0.96
232_G	266_L	1.171	0.96
90_G	240_S	1.168	0.96
65_T	182_L	1.166	0.96
363_D	379_D	1.165	0.96
84_E	245_F	1.163	0.96
367_V	378_E	1.161	0.96
249_F	259_A	1.159	0.96
113_R	116_S	1.154	0.96
315_E	363_D	1.153	0.96
176_A	236_H	1.150	0.96
365_V	380_R	1.148	0.96
367_V	387_V	1.147	0.96
191_Y	270_A	1.137	0.96
65_T	186_Q	1.133	0.96
158_T	268_W	1.133	0.96
124_L	138_V	1.132	0.96
266_L	270_A	1.126	0.95
300_I	337_P	1.120	0.95
351_V	390_H	1.116	0.95
97_W	111_A	1.113	0.95
321_E	327_V	1.112	0.95
250_A	256_E	1.107	0.95
316_I	383_I	1.104	0.95
197_I	273_A	1.099	0.95
30_G	127_W	1.099	0.95
43_T	271_I	1.097	0.95
128_V	169_A	1.088	0.95
53_A	56_D	1.083	0.94
83_R	89_E	1.083	0.94
184_L	234_S	1.074	0.94
64_D	322_A	1.070	0.94
122_P	125_S	1.065	0.94
94_E	97_W	1.063	0.94
214_D	260_Y	1.060	0.94
31_L	155_F	1.058	0.94
63_K	69_N	1.058	0.94
242_A	259_A	1.057	0.94
386_R	390_H	1.054	0.94
128_V	136_L	1.049	0.93
216_T	220_E	1.048	0.93
296_V	328_H	1.046	0.93
369_H	390_H	1.036	0.93
74_M	145_V	1.029	0.93
11_T	24_E	1.022	0.92
309_V	360_V	1.019	0.92
14_K	24_E	1.018	0.92
42_V	123_Y	1.017	0.92
175_A	179_E	1.015	0.92
385_D	388_H	1.013	0.92
214_D	236_H	1.011	0.92
173_D	260_Y	1.009	0.92
298_V	352_R	1.008	0.92
48_Y	52_E	1.006	0.92
33_D	126_Q	0.996	0.92
308_D	311_Q	0.996	0.92
189_R	192_E	0.994	0.91
372_D	390_H	0.993	0.91
33_D	127_W	0.989	0.91
250_A	255_A	0.983	0.91
24_E	28_K	0.980	0.91
279_S	285_V	0.980	0.91
37_M	110_L	0.977	0.91
71_Y	162_L	0.976	0.91
179_E	182_L	0.974	0.91
177_W	215_T	0.973	0.91
70_A	123_Y	0.973	0.91
54_I	271_I	0.972	0.90
58_L	266_L	0.970	0.90
325_V	387_V	0.970	0.90
345_E	348_G	0.968	0.90
302_Q	314_A	0.961	0.90
43_T	268_W	0.961	0.90
345_E	352_R	0.960	0.90
197_I	277_S	0.959	0.90
88_V	111_A	0.959	0.90
367_V	383_I	0.956	0.90
384_A	388_H	0.954	0.90
46_R	293_K	0.950	0.89
323_Q	384_A	0.950	0.89
79_D	83_R	0.950	0.89
367_V	386_R	0.949	0.89
54_I	270_A	0.949	0.89
242_A	258_T	0.948	0.89
315_E	380_R	0.945	0.89
50_L	286_L	0.944	0.89
51_W	162_L	0.942	0.89
297_I	329_F	0.940	0.89
185_D	201_R	0.940	0.89
102_G	108_Q	0.939	0.89
137_R	179_E	0.935	0.89
182_L	186_Q	0.931	0.88
33_D	44_R	0.931	0.88
328_H	349_V	0.930	0.88
14_K	281_D	0.920	0.88
365_V	383_I	0.919	0.88
298_V	337_P	0.915	0.88
229_V	273_A	0.913	0.88
96_A	147_W	0.912	0.87
82_E	85_K	0.911	0.87
319_E	322_A	0.911	0.87
181_T	185_D	0.906	0.87
49_A	63_K	0.906	0.87
313_G	355_I	0.906	0.87
316_I	319_E	0.906	0.87
243_D	258_T	0.903	0.87
155_F	158_T	0.900	0.87
310_E	314_A	0.899	0.87
137_R	182_L	0.895	0.86
43_T	47_G	0.890	0.86
44_R	123_Y	0.887	0.86
54_I	190_L	0.886	0.86
339_F	344_W	0.880	0.86
336_N	339_F	0.878	0.85
30_G	347_N	0.877	0.85
158_T	161_F	0.875	0.85
371_P	390_H	0.873	0.85
310_E	331_D	0.870	0.85
319_E	323_Q	0.870	0.85
13_S	16_H	0.868	0.85
296_V	349_V	0.865	0.85
298_V	340_K	0.862	0.84
299_P	329_F	0.860	0.84
203_R	209_K	0.860	0.84
288_P	351_V	0.859	0.84
26_V	275_V	0.856	0.84
28_K	346_L	0.854	0.84
49_A	326_R	0.853	0.84
285_V	348_G	0.849	0.83
345_E	368_V	0.848	0.83
57_N	193_D	0.842	0.83
125_S	246_D	0.839	0.83
79_D	108_Q	0.839	0.83
288_P	391_L	0.836	0.82
51_W	268_W	0.836	0.82
162_L	268_W	0.834	0.82
33_D	123_Y	0.830	0.82
93_P	102_G	0.830	0.82
81_L	95_V	0.830	0.82
144_V	264_W	0.824	0.82
280_D	283_G	0.819	0.81
359_E	362_D	0.814	0.81
57_N	189_R	0.808	0.80
48_Y	162_L	0.804	0.80
367_V	390_H	0.802	0.80
351_V	369_H	0.802	0.80
56_D	64_D	0.799	0.80
184_L	201_R	0.797	0.79
85_K	91_F	0.797	0.79
212_G	225_D	0.792	0.79
48_Y	71_Y	0.791	0.79
170_H	262_T	0.790	0.79
171_A	175_A	0.788	0.79
43_T	158_T	0.778	0.78
352_R	375_S	0.776	0.78
378_E	386_R	0.775	0.77
76_I	119_I	0.770	0.77
72_F	123_Y	0.769	0.77
58_L	268_W	0.762	0.76
380_R	384_A	0.758	0.76
288_P	294_Q	0.757	0.76
319_E	363_D	0.757	0.76
325_V	391_L	0.756	0.76
21_W	278_H	0.754	0.75
327_V	331_D	0.750	0.75
74_M	112_V	0.750	0.75
54_I	290_V	0.750	0.75
55_Q	59_D	0.749	0.75
75_F	96_A	0.746	0.75
35_A	42_V	0.743	0.74
203_R	215_T	0.743	0.74
31_L	50_L	0.739	0.74
362_D	377_V	0.735	0.74
96_A	112_V	0.734	0.74
65_T	137_R	0.734	0.74
339_F	346_L	0.732	0.73
20_D	24_E	0.732	0.73
122_P	126_Q	0.731	0.73
390_H	394_V	0.728	0.73
173_D	214_D	0.727	0.73
333_D	340_K	0.727	0.73
37_M	40_F	0.727	0.73
247_I	261_T	0.726	0.73
288_P	394_V	0.723	0.72
223_M	229_V	0.721	0.72
315_E	318_A	0.717	0.72
48_Y	55_Q	0.717	0.72
196_G	395_Y	0.715	0.72
124_L	136_L	0.714	0.71
6_Q	9_G	0.712	0.71
174_E	178_A	0.711	0.71
19_G	23_A	0.711	0.71
40_F	75_F	0.710	0.71
308_D	312_Y	0.709	0.71
21_W	279_S	0.706	0.71
174_E	177_W	0.703	0.70
62_F	186_Q	0.702	0.70
191_Y	266_L	0.700	0.70
382_A	388_H	0.699	0.70
173_D	236_H	0.695	0.69
288_P	390_H	0.694	0.69
247_I	259_A	0.694	0.69
164_Q	187_Y	0.692	0.69
144_V	161_F	0.691	0.69
289_T	392_D	0.690	0.69
120_I	138_V	0.688	0.69
231_G	270_A	0.687	0.69
30_G	343_E	0.687	0.69
337_P	344_W	0.684	0.68
355_I	365_V	0.682	0.68
156_F	229_V	0.681	0.68
56_D	59_D	0.681	0.68
18_P	276_M	0.679	0.68
339_F	342_N	0.678	0.68
36_P	123_Y	0.677	0.67
351_V	391_L	0.677	0.67
100_Q	109_R	0.677	0.67
344_W	352_R	0.673	0.67
144_V	267_S	0.671	0.67
44_R	127_W	0.669	0.66
295_V	327_V	0.666	0.66
208_D	211_P	0.666	0.66
87_I	240_S	0.666	0.66
170_H	176_A	0.662	0.66
129_R	250_A	0.661	0.66
137_R	166_G	0.660	0.65
205_P	208_D	0.657	0.65
31_L	275_V	0.655	0.65
58_L	141_W	0.654	0.65
95_V	111_A	0.654	0.65
78_E	111_A	0.652	0.64
344_W	347_N	0.652	0.64
23_A	34_Y	0.651	0.64
190_L	266_L	0.650	0.64
392_D	395_Y	0.650	0.64
210_F	213_A	0.649	0.64
68_E	136_L	0.649	0.64
129_R	136_L	0.648	0.64
26_V	123_Y	0.647	0.64
355_I	360_V	0.647	0.64
299_P	302_Q	0.647	0.64
19_G	108_Q	0.646	0.64
295_V	353_F	0.646	0.64
74_M	143_S	0.641	0.63
158_T	162_L	0.640	0.63
234_S	263_S	0.638	0.63
310_E	329_F	0.637	0.63
62_F	190_L	0.636	0.63
376_T	382_A	0.635	0.62
124_L	128_V	0.635	0.62
345_E	375_S	0.634	0.62
32_A	43_T	0.633	0.62
176_A	237_L	0.630	0.62
358_N	377_V	0.629	0.62
301_W	309_V	0.628	0.62
163_W	262_T	0.628	0.62
385_D	396_D	0.627	0.61
383_I	388_H	0.625	0.61
358_N	364_E	0.624	0.61
365_V	378_E	0.624	0.61
12_E	24_E	0.624	0.61
322_A	389_D	0.623	0.61
47_G	271_I	0.622	0.61
212_G	224_P	0.622	0.61
65_T	183_R	0.621	0.61
318_A	321_E	0.621	0.61
10_I	14_K	0.621	0.61
60_G	324_G	0.621	0.61
279_S	284_L	0.619	0.60
223_M	273_A	0.619	0.60
337_P	340_K	0.618	0.60
75_F	110_L	0.618	0.60
121_A	258_T	0.617	0.60
376_T	390_H	0.615	0.60
91_F	114_P	0.614	0.60
15_E	18_P	0.612	0.60
87_I	118_S	0.611	0.59
216_T	222_L	0.609	0.59
386_R	393_E	0.609	0.59
384_A	393_E	0.609	0.59
36_P	40_F	0.608	0.59
12_E	19_G	0.608	0.59
317_A	331_D	0.607	0.59
324_G	327_V	0.606	0.59
316_I	380_R	0.606	0.59
89_E	244_A	0.603	0.58
390_H	393_E	0.603	0.58
378_E	382_A	0.603	0.58
320_L	384_A	0.601	0.58
92_D	95_V	0.601	0.58
295_V	387_V	0.601	0.58
46_R	328_H	0.598	0.58
43_T	51_W	0.598	0.58
339_F	343_E	0.597	0.58
391_L	395_Y	0.596	0.58
62_F	183_R	0.596	0.58
153_K	156_F	0.591	0.57
175_A	236_H	0.591	0.57
325_V	384_A	0.591	0.57
31_L	284_L	0.591	0.57
318_A	323_Q	0.589	0.57
324_G	329_F	0.589	0.57
363_D	382_A	0.589	0.57
358_N	375_S	0.588	0.57
298_V	344_W	0.588	0.57
278_H	285_V	0.587	0.56
387_V	391_L	0.587	0.56
240_S	244_A	0.586	0.56
187_Y	264_W	0.586	0.56
302_Q	310_E	0.586	0.56
56_D	63_K	0.584	0.56
84_E	241_F	0.583	0.56
354_E	366_T	0.583	0.56
285_V	371_P	0.582	0.56
308_D	385_D	0.582	0.56
275_V	278_H	0.580	0.56
178_A	181_T	0.580	0.56
101_G	147_W	0.579	0.55
372_D	394_V	0.578	0.55
177_W	366_T	0.577	0.55
11_T	346_L	0.577	0.55
337_P	345_E	0.576	0.55
6_Q	68_E	0.575	0.55
252_E	381_A	0.574	0.55
214_D	238_G	0.573	0.55
38_G	159_K	0.573	0.55
239_Q	258_T	0.572	0.55
355_I	380_R	0.572	0.55
215_T	236_H	0.571	0.54
72_F	127_W	0.571	0.54
34_Y	154_P	0.570	0.54
9_G	358_N	0.569	0.54
319_E	383_I	0.569	0.54
96_A	145_V	0.568	0.54
123_Y	127_W	0.567	0.54
289_T	395_Y	0.567	0.54
23_A	154_P	0.566	0.54
324_G	388_H	0.566	0.54
179_E	215_T	0.564	0.54
322_A	385_D	0.564	0.54
320_L	325_V	0.563	0.53
32_A	41_I	0.563	0.53
13_S	281_D	0.563	0.53
388_H	391_L	0.562	0.53
141_W	164_Q	0.560	0.53
66_G	321_E	0.559	0.53
195_L	270_A	0.559	0.53
298_V	328_H	0.559	0.53
38_G	119_I	0.558	0.53
301_W	337_P	0.558	0.53
354_E	375_S	0.558	0.53
255_A	308_D	0.558	0.53
193_D	289_T	0.556	0.52
299_P	337_P	0.555	0.52
61_W	193_D	0.555	0.52
323_Q	385_D	0.554	0.52
295_V	319_E	0.554	0.52
360_V	365_V	0.553	0.52
303_E	308_D	0.551	0.52
232_G	270_A	0.550	0.52
319_E	377_V	0.549	0.52
368_V	373_G	0.548	0.51
295_V	320_L	0.546	0.51
308_D	357_P	0.545	0.51
210_F	278_H	0.545	0.51
246_D	258_T	0.543	0.51
59_D	141_W	0.543	0.51
52_E	56_D	0.541	0.51
302_Q	329_F	0.540	0.50
296_V	299_P	0.540	0.50
25_V	28_K	0.539	0.50
179_E	262_T	0.539	0.50
66_G	393_E	0.538	0.50
128_V	143_S	0.536	0.50
42_V	210_F	0.536	0.50
285_V	370_R	0.535	0.50
76_I	94_E	0.533	0.50
302_Q	307_D	0.533	0.50
286_L	291_A	0.533	0.50
53_A	294_Q	0.533	0.50
330_D	337_P	0.533	0.50
52_E	59_D	0.532	0.49
165_E	262_T	0.531	0.49
312_Y	359_E	0.529	0.49
338_G	352_R	0.529	0.49
76_I	120_I	0.526	0.49
372_D	376_T	0.526	0.49
116_S	140_Q	0.526	0.49
12_E	339_F	0.525	0.48
388_H	393_E	0.524	0.48
11_T	20_D	0.523	0.48
71_Y	142_N	0.523	0.48
312_Y	316_I	0.521	0.48
128_V	259_A	0.520	0.48
212_G	220_E	0.520	0.48
62_F	164_Q	0.519	0.48
186_Q	189_R	0.519	0.48
42_V	128_V	0.518	0.48
351_V	384_A	0.517	0.47
71_Y	74_M	0.517	0.47
316_I	353_F	0.517	0.47
17_S	27_Q	0.517	0.47
191_Y	231_G	0.516	0.47
36_P	159_K	0.516	0.47
323_Q	393_E	0.515	0.47
297_I	327_V	0.515	0.47
62_F	237_L	0.515	0.47
312_Y	383_I	0.515	0.47
35_A	122_P	0.514	0.47
301_W	336_N	0.514	0.47
83_R	109_R	0.514	0.47
56_D	185_D	0.514	0.47
322_A	384_A	0.513	0.47
57_N	290_V	0.513	0.47
314_A	389_D	0.511	0.47
303_E	309_V	0.511	0.47
25_V	29_A	0.510	0.47
112_V	272_G	0.510	0.47
8_L	12_E	0.510	0.47
273_A	277_S	0.509	0.46
242_A	260_Y	0.508	0.46
72_F	76_I	0.508	0.46
282_Q	345_E	0.507	0.46
12_E	20_D	0.507	0.46
294_Q	325_V	0.506	0.46
26_V	32_A	0.505	0.46
173_D	181_T	0.503	0.46
42_V	73_P	0.503	0.46
131_H	250_A	0.503	0.46
280_D	370_R	0.503	0.46
197_I	231_G	0.502	0.46
48_Y	51_W	0.501	0.45
359_E	377_V	0.500	0.45
180_T	219_V	0.500	0.45

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4ncxA	2	0.9022	100	0.27	Contact Map
3ialA	2	0.9481	100	0.279	Contact Map
1hc7A	2	0.9202	100	0.287	Contact Map
4hvcA	2	0.9541	100	0.29	Contact Map
1nj1A	2	0.9202	100	0.297	Contact Map
1nj8A	2	0.9022	100	0.303	Contact Map
1qf6A	1	0.7625	100	0.526	Contact Map
2i4lA	2	0.7545	100	0.531	Contact Map
1nyrA	2	0.7605	100	0.536	Contact Map
2j3lA	2	0.7685	100	0.55	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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