Q9HS43 - HALSA - GREMLIN Contacts

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Q9HS43 - Phosphoribosylaminoimidazole-succinocarboxamide formyltransferase

UniProt:	Q9HS43	Sequences: MPPTGGARRKSLPIPPTHEDVHFPATDARNTPLVCEFMDTRSCGTTTALREAAGVVSMSTIAGLASNRGRNLLHLADQQPGGADLGVVVSNHADAPVLDAAADRDIPTVVVERRAEESRRDHERRVVAALDDYDIDVVCLDGYMRVLSEVFLDAMPTTLNVHPSLLPAFPGRNAHEQVLDAGVSVSGCTVHVVTNAVAEDGSVRTGDVDGGPIVTQESVPVFEDDTAATLKTRVRQDAEFEAYPRAIRQFAAGELDATTDGVSRADSDDAATFPARRLTGTTREDVLRYGENPHQDAAVYRDNTHAAASVVHADQLNPDAKALSYNNYNDADAALALVREFDDGPAAAVIKHTNPAGCATADTLADAYSDALSTDAKSAFGGIVALNRECDAETATRVADSFKEVVVAPGYTDDAVDVLTAKSNLRVLDVGTLDGTPAPVTETPLVGGRLVQERNTWAPTADDLEVVTKREPTAAEVETMLFAWRVLTHVKSNGILFAAGTETVGLGVGQVSRVDAVEIAAKKAERDANGKTADGAVMASDAFFPFPDGIAAAAEAGIEAVIQPGGSKNDDQVIEAANEHGMAMVFTGHRAFRHD	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	595 (464)
Sequences:	2852 (1413)
Seq/√Len:	65.6

ECOLI - PUR9
BACSU - PUR9
HALSA - Q9HS43

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
571_D	575_E	5.611	1.00
469_K	578_N	5.368	1.00
470_R	476_E	4.306	1.00
389_E	410_G	3.968	1.00
233_R	245_R	3.936	1.00
547_P	551_A	3.742	1.00
389_E	412_T	3.735	1.00
314_D	429_D	3.590	1.00
283_R	286_V	3.564	1.00
397_R	400_D	3.376	1.00
392_A	418_V	3.260	1.00
410_G	429_D	3.202	1.00
215_T	246_A	3.150	1.00
411_Y	427_V	2.947	1.00
346_A	360_T	2.815	1.00
392_A	414_D	2.789	1.00
169_F	186_S	2.780	1.00
174_A	180_D	2.779	1.00
550_I	561_V	2.765	1.00
358_C	486_V	2.762	1.00
391_D	394_T	2.643	1.00
171_G	178_V	2.613	1.00
145_R	149_E	2.573	1.00
215_T	227_A	2.495	1.00
230_L	245_R	2.440	1.00
457_W	589_H	2.435	1.00
347_A	386_L	2.418	1.00
392_A	396_T	2.412	1.00
563_Q	584_M	2.356	1.00
518_E	522_K	2.338	1.00
176_E	180_D	2.316	1.00
551_A	579_E	2.306	1.00
328_Y	445_L	2.238	1.00
363_T	366_D	2.235	1.00
547_P	572_Q	2.218	1.00
508_V	511_V	2.200	1.00
285_D	322_A	2.170	1.00
125_R	128_A	2.135	1.00
483_A	498_A	2.132	1.00
146_V	150_V	2.052	1.00
202_S	205_T	2.050	1.00
473_T	476_E	2.034	1.00
174_A	181_A	2.022	1.00
569_N	572_Q	2.021	1.00
281_T	449_R	2.006	1.00
228_A	237_D	1.981	1.00
497_F	521_A	1.978	1.00
479_T	498_A	1.964	1.00
365_A	369_S	1.902	1.00
364_L	386_L	1.900	1.00
517_V	549_G	1.897	1.00
236_Q	241_E	1.897	1.00
575_E	578_N	1.886	1.00
575_E	579_E	1.886	1.00
144_M	148_S	1.879	1.00
512_S	523_K	1.876	1.00
386_L	390_C	1.863	1.00
547_P	579_E	1.853	1.00
361_A	370_D	1.852	1.00
538_M	553_A	1.847	1.00
413_D	417_D	1.822	1.00
284_E	301_R	1.821	1.00
398_V	403_K	1.807	1.00
476_E	559_E	1.775	1.00
126_V	237_D	1.766	1.00
155_M	178_V	1.747	1.00
325_Y	441_T	1.736	1.00
329_N	353_T	1.735	1.00
126_V	228_A	1.728	1.00
416_V	420_T	1.710	0.99
329_N	443_T	1.697	0.99
384_V	398_V	1.696	0.99
369_S	397_R	1.689	0.99
194_T	256_D	1.686	0.99
537_V	560_A	1.685	0.99
468_T	584_M	1.679	0.99
497_F	504_V	1.677	0.99
479_T	499_A	1.664	0.99
126_V	187_G	1.663	0.99
362_D	366_D	1.660	0.99
460_T	463_D	1.624	0.99
345_P	364_L	1.619	0.99
551_A	555_E	1.615	0.99
175_H	178_V	1.607	0.99
361_A	366_D	1.601	0.99
317_N	420_T	1.593	0.99
173_N	176_E	1.589	0.99
317_N	425_L	1.586	0.99
331_A	405_V	1.584	0.99
576_A	579_E	1.575	0.99
154_A	217_E	1.569	0.99
174_A	178_V	1.566	0.99
230_L	233_R	1.536	0.99
551_A	580_H	1.532	0.99
515_D	523_K	1.521	0.99
536_A	558_I	1.521	0.99
174_A	182_G	1.518	0.99
464_L	481_L	1.514	0.99
534_D	559_E	1.514	0.99
178_V	182_G	1.507	0.99
576_A	580_H	1.506	0.99
465_E	588_G	1.504	0.99
167_P	183_V	1.501	0.99
470_R	559_E	1.493	0.99
215_T	229_T	1.491	0.99
154_A	181_A	1.483	0.98
299_V	445_L	1.482	0.98
316_L	429_D	1.474	0.98
461_A	481_L	1.462	0.98
173_N	180_D	1.458	0.98
475_A	479_T	1.447	0.98
340_E	489_H	1.441	0.98
538_M	558_I	1.440	0.98
399_A	421_A	1.424	0.98
384_V	403_K	1.423	0.98
479_T	500_G	1.423	0.98
475_A	500_G	1.419	0.98
464_L	562_I	1.418	0.98
480_M	560_A	1.418	0.98
186_S	213_I	1.418	0.98
129_A	133_Y	1.408	0.98
340_E	488_T	1.403	0.98
173_N	177_Q	1.403	0.98
552_A	555_E	1.401	0.98
124_R	146_V	1.401	0.98
273_F	298_A	1.395	0.98
323_L	328_Y	1.389	0.98
440_V	453_E	1.385	0.98
229_T	249_Q	1.383	0.98
174_A	177_Q	1.381	0.98
550_I	573_V	1.375	0.98
178_V	181_A	1.372	0.97
317_N	419_L	1.368	0.97
177_Q	180_D	1.365	0.97
547_P	580_H	1.357	0.97
479_T	501_T	1.356	0.97
349_V	379_A	1.351	0.97
127_V	147_L	1.344	0.97
204_R	261_G	1.340	0.97
244_P	248_R	1.340	0.97
561_V	582_M	1.340	0.97
335_L	430_V	1.335	0.97
478_E	501_T	1.334	0.97
366_D	370_D	1.321	0.97
174_A	179_L	1.311	0.97
238_A	242_A	1.292	0.96
296_D	453_E	1.287	0.96
227_A	246_A	1.284	0.96
442_E	449_R	1.279	0.96
172_R	224_D	1.266	0.96
390_C	411_Y	1.257	0.96
416_V	427_V	1.253	0.96
547_P	576_A	1.252	0.96
244_P	261_G	1.243	0.95
273_F	296_D	1.232	0.95
200_D	203_V	1.231	0.95
129_A	132_D	1.227	0.95
176_E	179_L	1.218	0.95
555_E	580_H	1.213	0.95
135_I	185_V	1.213	0.95
124_R	150_V	1.212	0.95
497_F	536_A	1.204	0.95
194_T	249_Q	1.202	0.95
194_T	198_A	1.202	0.95
521_A	556_A	1.200	0.94
552_A	556_A	1.197	0.94
354_N	508_V	1.196	0.94
213_I	218_S	1.195	0.94
213_I	217_E	1.194	0.94
466_V	585_V	1.174	0.94
222_F	240_F	1.166	0.94
474_A	478_E	1.160	0.93
155_M	177_Q	1.157	0.93
200_D	204_R	1.152	0.93
177_Q	181_A	1.147	0.93
338_V	385_A	1.143	0.93
461_A	477_V	1.136	0.93
272_T	296_D	1.131	0.93
365_A	397_R	1.122	0.92
365_A	393_E	1.120	0.92
204_R	240_F	1.119	0.92
554_A	582_M	1.116	0.92
125_R	235_R	1.113	0.92
508_V	519_I	1.112	0.92
455_N	591_A	1.110	0.92
175_H	180_D	1.108	0.92
374_T	503_T	1.105	0.92
394_T	398_V	1.103	0.92
299_V	311_V	1.100	0.91
131_D	137_V	1.099	0.91
407_V	430_V	1.099	0.91
380_F	568_K	1.099	0.91
497_F	558_I	1.098	0.91
332_D	336_A	1.095	0.91
414_D	417_D	1.093	0.91
171_G	175_H	1.092	0.91
226_T	242_A	1.091	0.91
392_A	412_T	1.086	0.91
204_R	222_F	1.085	0.91
568_K	571_D	1.083	0.91
317_N	427_V	1.081	0.91
470_R	581_G	1.077	0.91
550_I	577_A	1.075	0.91
396_T	400_D	1.069	0.90
574_I	586_F	1.066	0.90
369_S	373_S	1.063	0.90
476_E	583_A	1.052	0.90
121_D	232_T	1.051	0.90
118_S	192_V	1.049	0.89
315_Q	322_A	1.047	0.89
466_V	472_P	1.047	0.89
338_V	346_A	1.042	0.89
364_L	394_T	1.037	0.89
393_E	396_T	1.036	0.89
373_S	502_E	1.028	0.88
374_T	502_E	1.028	0.88
504_V	533_A	1.028	0.88
233_R	236_Q	1.021	0.88
194_T	252_A	1.020	0.88
195_N	199_E	1.018	0.88
237_D	242_A	1.018	0.88
481_L	562_I	1.013	0.88
166_L	217_E	1.011	0.88
335_L	339_R	1.010	0.88
169_F	214_V	1.006	0.87
229_T	233_R	1.005	0.87
511_V	519_I	1.004	0.87
503_T	506_L	1.002	0.87
238_A	241_E	0.999	0.87
222_F	243_Y	0.995	0.87
337_L	348_A	0.987	0.86
372_L	376_A	0.984	0.86
472_P	585_V	0.983	0.86
466_V	471_E	0.983	0.86
175_H	179_L	0.983	0.86
341_F	346_A	0.982	0.86
155_M	172_R	0.982	0.86
398_V	406_V	0.982	0.86
467_V	586_F	0.979	0.86
396_T	421_A	0.976	0.86
411_Y	429_D	0.973	0.86
214_V	217_E	0.973	0.86
550_I	554_A	0.972	0.85
128_A	132_D	0.971	0.85
310_V	313_A	0.970	0.85
173_N	179_L	0.969	0.85
472_P	476_E	0.969	0.85
386_L	394_T	0.967	0.85
399_A	425_L	0.967	0.85
363_T	393_E	0.966	0.85
419_L	427_V	0.961	0.85
331_A	428_L	0.961	0.85
495_I	541_D	0.959	0.85
515_D	518_E	0.956	0.85
377_K	515_D	0.955	0.84
364_L	388_R	0.955	0.84
372_L	401_S	0.949	0.84
464_L	477_V	0.948	0.84
173_N	178_V	0.948	0.84
122_H	125_R	0.947	0.84
472_P	583_A	0.945	0.84
186_S	227_A	0.944	0.84
248_R	252_A	0.943	0.84
490_V	496_L	0.942	0.84
313_A	428_L	0.939	0.83
459_P	464_L	0.933	0.83
347_A	398_V	0.927	0.83
274_P	298_A	0.924	0.82
470_R	583_A	0.919	0.82
169_F	215_T	0.911	0.82
514_V	549_G	0.910	0.81
460_T	481_L	0.906	0.81
255_L	280_G	0.905	0.81
360_T	501_T	0.904	0.81
560_A	583_A	0.901	0.81
343_D	388_R	0.900	0.81
331_A	407_V	0.900	0.81
388_R	409_P	0.896	0.80
410_G	431_G	0.891	0.80
478_E	481_L	0.891	0.80
364_L	391_D	0.888	0.80
169_F	227_A	0.887	0.80
551_A	576_A	0.886	0.80
350_I	385_A	0.886	0.80
131_D	147_L	0.884	0.80
368_Y	401_S	0.881	0.79
497_F	538_M	0.881	0.79
369_S	400_D	0.880	0.79
549_G	573_V	0.879	0.79
386_L	398_V	0.878	0.79
496_L	503_T	0.878	0.79
391_D	412_T	0.877	0.79
155_M	167_P	0.874	0.79
279_T	449_R	0.872	0.79
572_Q	575_E	0.872	0.79
554_A	580_H	0.871	0.79
439_P	454_R	0.870	0.78
123_E	137_V	0.867	0.78
550_I	558_I	0.862	0.78
563_Q	586_F	0.857	0.77
194_T	282_T	0.856	0.77
483_A	537_V	0.856	0.77
166_L	213_I	0.855	0.77
559_E	581_G	0.855	0.77
511_V	515_D	0.854	0.77
123_E	127_V	0.854	0.77
156_P	174_A	0.852	0.77
347_A	384_V	0.849	0.77
154_A	167_P	0.847	0.77
137_V	150_V	0.847	0.77
124_R	128_A	0.844	0.76
226_T	238_A	0.842	0.76
518_E	552_A	0.839	0.76
299_V	328_Y	0.838	0.76
333_A	353_T	0.836	0.76
341_F	486_V	0.836	0.76
251_A	258_T	0.835	0.76
333_A	354_N	0.829	0.75
345_P	388_R	0.828	0.75
146_V	149_E	0.828	0.75
465_E	571_D	0.828	0.75
366_D	369_S	0.823	0.75
497_F	533_A	0.819	0.74
273_F	283_R	0.816	0.74
346_A	358_C	0.814	0.74
283_R	298_A	0.814	0.74
523_K	533_A	0.807	0.73
226_T	237_D	0.804	0.73
167_P	178_V	0.802	0.73
196_A	207_D	0.800	0.72
321_K	404_E	0.798	0.72
199_E	207_D	0.798	0.72
377_K	512_S	0.795	0.72
517_V	550_I	0.795	0.72
201_G	204_R	0.791	0.72
411_Y	428_L	0.786	0.71
154_A	183_V	0.783	0.71
533_A	536_A	0.782	0.71
167_P	181_A	0.782	0.71
248_R	258_T	0.781	0.71
282_T	301_R	0.780	0.70
348_A	358_C	0.780	0.70
416_V	429_D	0.779	0.70
166_L	214_V	0.779	0.70
547_P	573_V	0.779	0.70
538_M	550_I	0.778	0.70
337_L	486_V	0.777	0.70
475_A	478_E	0.775	0.70
145_R	148_S	0.775	0.70
497_F	517_V	0.774	0.70
420_T	425_L	0.774	0.70
137_V	322_A	0.771	0.70
155_M	174_A	0.771	0.70
199_E	202_S	0.769	0.69
571_D	578_N	0.766	0.69
571_D	579_E	0.765	0.69
411_Y	416_V	0.764	0.69
218_S	225_D	0.764	0.69
196_A	199_E	0.764	0.69
354_N	511_V	0.764	0.69
512_S	515_D	0.762	0.69
342_D	388_R	0.758	0.68
252_A	256_D	0.757	0.68
368_Y	397_R	0.752	0.68
197_V	260_D	0.750	0.67
440_V	451_V	0.749	0.67
554_A	576_A	0.748	0.67
457_W	463_D	0.747	0.67
123_E	146_V	0.747	0.67
156_P	172_R	0.746	0.67
521_A	549_G	0.745	0.67
165_L	217_E	0.744	0.67
468_T	563_Q	0.742	0.67
396_T	399_A	0.742	0.67
287_L	328_Y	0.741	0.67
377_K	518_E	0.740	0.66
399_A	418_V	0.739	0.66
231_K	234_V	0.738	0.66
477_V	562_I	0.738	0.66
128_A	131_D	0.737	0.66
477_V	481_L	0.736	0.66
359_A	379_A	0.735	0.66
421_A	425_L	0.735	0.66
248_R	276_R	0.734	0.66
406_V	419_L	0.734	0.66
482_F	498_A	0.729	0.65
465_E	471_E	0.729	0.65
480_M	585_V	0.727	0.65
517_V	538_M	0.727	0.65
267_S	270_A	0.727	0.65
156_P	177_Q	0.726	0.65
343_D	360_T	0.725	0.65
364_L	390_C	0.723	0.65
511_V	523_K	0.721	0.64
255_L	278_L	0.717	0.64
195_N	198_A	0.716	0.64
223_E	240_F	0.716	0.64
506_L	511_V	0.715	0.64
138_V	165_L	0.714	0.64
215_T	226_T	0.711	0.63
164_S	182_G	0.711	0.63
547_P	569_N	0.709	0.63
453_E	456_T	0.709	0.63
390_C	394_T	0.707	0.63
331_A	385_A	0.705	0.63
537_V	583_A	0.704	0.63
441_T	444_P	0.703	0.62
393_E	412_T	0.703	0.62
314_D	410_G	0.703	0.62
121_D	231_K	0.702	0.62
335_L	431_G	0.702	0.62
502_E	532_T	0.700	0.62
362_D	388_R	0.699	0.62
326_N	404_E	0.696	0.62
470_R	578_N	0.692	0.61
155_M	171_G	0.688	0.61
524_A	533_A	0.687	0.61
302_D	444_P	0.687	0.61
119_R	195_N	0.687	0.61
176_E	181_A	0.685	0.60
459_P	589_H	0.684	0.60
213_I	240_F	0.683	0.60
241_E	244_P	0.683	0.60
515_D	529_N	0.682	0.60
349_V	491_K	0.681	0.60
403_K	425_L	0.681	0.60
310_V	331_A	0.680	0.60
349_V	359_A	0.679	0.60
530_G	533_A	0.679	0.60
414_D	418_V	0.678	0.60
416_V	419_L	0.678	0.60
353_T	443_T	0.677	0.60
277_R	281_T	0.676	0.59
406_V	425_L	0.671	0.59
504_V	532_T	0.670	0.59
198_A	256_D	0.670	0.59
515_D	549_G	0.669	0.59
173_N	181_A	0.668	0.59
332_D	448_G	0.667	0.58
531_K	534_D	0.667	0.58
154_A	177_Q	0.666	0.58
573_V	577_A	0.666	0.58
361_A	502_E	0.665	0.58
257_A	261_G	0.665	0.58
468_T	578_N	0.664	0.58
511_V	516_A	0.664	0.58
423_S	568_K	0.664	0.58
461_A	478_E	0.663	0.58
329_N	332_D	0.662	0.58
499_A	559_E	0.662	0.58
374_T	515_D	0.660	0.58
490_V	511_V	0.658	0.57
377_K	529_N	0.657	0.57
353_T	405_V	0.656	0.57
516_A	519_I	0.656	0.57
497_F	531_K	0.654	0.57
479_T	537_V	0.653	0.57
361_A	394_T	0.653	0.57
283_R	300_Y	0.653	0.57
512_S	533_A	0.650	0.56
337_L	358_C	0.649	0.56
483_A	539_A	0.649	0.56
312_H	431_G	0.649	0.56
124_R	149_E	0.649	0.56
169_F	246_A	0.648	0.56
497_F	512_S	0.647	0.56
550_I	582_M	0.647	0.56
379_A	403_K	0.643	0.56
240_F	244_P	0.643	0.56
467_V	574_I	0.640	0.55
169_F	217_E	0.640	0.55
382_G	403_K	0.640	0.55
266_D	271_A	0.640	0.55
561_V	573_V	0.639	0.55
413_D	416_V	0.638	0.55
370_D	501_T	0.638	0.55
337_L	340_E	0.636	0.55
274_P	300_Y	0.635	0.55
276_R	280_G	0.635	0.55
140_L	156_P	0.634	0.55
349_V	372_L	0.633	0.54
457_W	460_T	0.633	0.54
203_V	222_F	0.632	0.54
175_H	224_D	0.631	0.54
309_S	446_V	0.631	0.54
248_R	261_G	0.630	0.54
169_F	219_V	0.627	0.54
380_F	400_D	0.623	0.53
420_T	427_V	0.622	0.53
325_Y	444_P	0.621	0.53
515_D	519_I	0.621	0.53
498_A	539_A	0.620	0.53
190_V	215_T	0.619	0.53
197_V	201_G	0.619	0.53
148_S	287_L	0.618	0.53
248_R	275_A	0.618	0.53
341_F	345_P	0.617	0.53
189_T	231_K	0.617	0.53
512_S	531_K	0.616	0.53
273_F	440_V	0.615	0.52
553_A	558_I	0.615	0.52
118_S	207_D	0.615	0.52
508_V	523_K	0.614	0.52
196_A	200_D	0.614	0.52
275_A	282_T	0.614	0.52
515_D	521_A	0.612	0.52
243_Y	261_G	0.611	0.52
347_A	368_Y	0.611	0.52
277_R	451_V	0.610	0.52
346_A	361_A	0.610	0.52
331_A	335_L	0.609	0.52
308_A	335_L	0.608	0.52
370_D	500_G	0.608	0.52
313_A	331_A	0.607	0.51
461_A	464_L	0.606	0.51
247_I	254_E	0.605	0.51
349_V	405_V	0.603	0.51
185_V	226_T	0.601	0.51
551_A	572_Q	0.595	0.50
496_L	506_L	0.595	0.50
469_K	581_G	0.594	0.50
554_A	579_E	0.593	0.50
178_V	183_V	0.593	0.50
314_D	416_V	0.593	0.50
175_H	182_G	0.592	0.50
317_N	416_V	0.591	0.50
484_W	587_T	0.591	0.50
167_P	217_E	0.590	0.49
417_D	420_T	0.589	0.49
156_P	217_E	0.588	0.49
161_V	166_L	0.588	0.49
584_M	587_T	0.586	0.49
154_A	213_I	0.586	0.49
197_V	256_D	0.585	0.49
171_G	213_I	0.585	0.49
155_M	175_H	0.584	0.49
187_G	228_A	0.581	0.48
317_N	577_A	0.581	0.48
217_E	257_A	0.580	0.48
469_K	579_E	0.579	0.48
329_N	379_A	0.579	0.48
127_V	213_I	0.578	0.48
309_S	313_A	0.578	0.48
337_L	593_R	0.577	0.48
410_G	413_D	0.577	0.48
126_V	129_A	0.576	0.48
544_F	549_G	0.575	0.48
355_P	506_L	0.575	0.48
248_R	280_G	0.575	0.48
368_Y	403_K	0.575	0.48
459_P	481_L	0.574	0.48
480_M	483_A	0.572	0.47
158_T	163_P	0.571	0.47
368_Y	372_L	0.571	0.47
335_L	446_V	0.571	0.47
174_A	183_V	0.571	0.47
391_D	414_D	0.570	0.47
390_C	398_V	0.570	0.47
441_T	454_R	0.566	0.47
365_A	394_T	0.566	0.47
486_V	511_V	0.566	0.47
281_T	442_E	0.565	0.47
412_T	415_A	0.565	0.47
213_I	247_I	0.563	0.46
380_F	544_F	0.563	0.46
498_A	537_V	0.563	0.46
496_L	508_V	0.563	0.46
245_R	275_A	0.562	0.46
487_L	494_G	0.561	0.46
192_V	195_N	0.560	0.46
359_A	479_T	0.559	0.46
396_T	418_V	0.558	0.46
486_V	503_T	0.558	0.46
187_G	234_V	0.558	0.46
538_M	561_V	0.557	0.46
337_L	489_H	0.556	0.45
334_A	385_A	0.555	0.45
494_G	541_D	0.554	0.45
515_D	552_A	0.554	0.45
139_C	212_P	0.554	0.45
498_A	501_T	0.554	0.45
293_P	483_A	0.554	0.45
118_S	123_E	0.553	0.45
179_L	182_G	0.551	0.45
147_L	150_V	0.550	0.45
345_P	394_T	0.550	0.45
468_T	586_F	0.550	0.45
395_A	418_V	0.549	0.45
490_V	506_L	0.548	0.45
321_K	424_N	0.548	0.45
266_D	270_A	0.547	0.44
390_C	415_A	0.547	0.44
341_F	489_H	0.546	0.44
197_V	202_S	0.546	0.44
512_S	522_K	0.545	0.44
140_L	299_V	0.543	0.44
279_T	442_E	0.543	0.44
226_T	239_E	0.542	0.44
163_P	167_P	0.541	0.44
310_V	407_V	0.540	0.44
472_P	578_N	0.540	0.44
233_R	242_A	0.539	0.44
372_L	379_A	0.539	0.44
299_V	323_L	0.538	0.43
384_V	401_S	0.538	0.43
514_V	552_A	0.537	0.43
187_G	308_A	0.536	0.43
301_R	312_H	0.535	0.43
554_A	577_A	0.535	0.43
510_Q	541_D	0.535	0.43
365_A	391_D	0.534	0.43
521_A	536_A	0.534	0.43
196_A	202_S	0.534	0.43
380_F	406_V	0.534	0.43
468_T	583_A	0.534	0.43
196_A	201_G	0.534	0.43
291_E	326_N	0.533	0.43
332_D	593_R	0.533	0.43
341_F	387_N	0.533	0.43
281_T	302_D	0.532	0.43
461_A	474_A	0.531	0.43
369_S	393_E	0.529	0.42
310_V	328_Y	0.529	0.42
338_V	350_I	0.529	0.42
158_T	161_V	0.528	0.42
217_E	249_Q	0.528	0.42
347_A	482_F	0.528	0.42
510_Q	519_I	0.528	0.42
468_T	472_P	0.528	0.42
481_L	485_R	0.528	0.42
379_A	514_V	0.528	0.42
442_E	451_V	0.527	0.42
332_D	441_T	0.526	0.42
248_R	266_D	0.526	0.42
521_A	552_A	0.526	0.42
345_P	386_L	0.525	0.42
308_A	312_H	0.524	0.42
169_F	183_V	0.524	0.42
296_D	463_D	0.524	0.42
197_V	261_G	0.524	0.42
277_R	440_V	0.523	0.42
135_I	172_R	0.523	0.42
353_T	546_F	0.523	0.42
167_P	171_G	0.523	0.42
169_F	213_I	0.522	0.42
285_D	328_Y	0.522	0.42
504_V	536_A	0.522	0.42
261_G	286_V	0.522	0.42
133_Y	226_T	0.521	0.41
358_C	503_T	0.521	0.41
127_V	187_G	0.520	0.41
497_F	520_A	0.520	0.41
239_E	253_G	0.516	0.41
385_A	406_V	0.515	0.41
127_V	131_D	0.515	0.41
122_H	128_A	0.515	0.41
392_A	417_D	0.514	0.41
523_K	549_G	0.514	0.41
373_S	376_A	0.514	0.41
372_L	397_R	0.514	0.41
213_I	249_Q	0.513	0.41
317_N	399_A	0.513	0.41
228_A	234_V	0.512	0.40
197_V	200_D	0.512	0.40
213_I	246_A	0.511	0.40
549_G	577_A	0.510	0.40
373_S	532_T	0.510	0.40
538_M	573_V	0.509	0.40
556_A	577_A	0.509	0.40
198_A	345_P	0.508	0.40
135_I	184_S	0.508	0.40
158_T	169_F	0.507	0.40
268_D	271_A	0.507	0.40
335_L	338_V	0.507	0.40
347_A	364_L	0.507	0.40
355_P	490_V	0.506	0.40
514_V	517_V	0.506	0.40
269_D	272_T	0.506	0.40
341_F	358_C	0.506	0.40
499_A	504_V	0.506	0.40
350_I	358_C	0.506	0.40
467_V	584_M	0.505	0.40
309_S	335_L	0.505	0.40
137_V	147_L	0.505	0.40
122_H	134_D	0.505	0.40
516_A	549_G	0.505	0.40
317_N	405_V	0.505	0.40
325_Y	451_V	0.504	0.40
154_A	224_D	0.504	0.40
325_Y	563_Q	0.503	0.39
368_Y	398_V	0.503	0.39
294_H	455_N	0.503	0.39
370_D	502_E	0.503	0.39
406_V	552_A	0.502	0.39
127_V	150_V	0.501	0.39
204_R	558_I	0.500	0.39

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3zzmA	2	0.805	100	0.309	Contact Map
4ehiA	2	0.8	100	0.321	Contact Map
1zczA	2	0.7277	100	0.342	Contact Map
1g8mA	2	0.7815	100	0.344	Contact Map
4j6eA	2	0.3529	100	0.862	Contact Map
2ywrA	2	0.3563	99.6	0.941	Contact Map
3p9xA	2	0.321	99.5	0.941	Contact Map
4ew1A	2	0.3378	99.5	0.942	Contact Map
1jkxA	2	0.3445	99.5	0.942	Contact Map
3av3A	1	0.3092	99.5	0.942	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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