Q9HS42 - HALSA - GREMLIN Contacts

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Q9HS42 - Adenylosuccinate lyase

UniProt:	Q9HS42	Sequences: MNSHTNGVFRASVAGKCTSSCVGGIGRLLRRAPPVGGMTDDHALYAVSPLDGRYSGRTDALAPYVSEAALMRARVEVEAEYVLALADLDAVPLELVGDERTALRDAYKTFDAADADLVKRIETEGALGHAATNHDVKAVEYFLREHAPARAHSWIHFGLTSEDVNNLAYRLLVDGAITAVLTPELRGLRDDLVSFAHDYADLPMLARTHGQPATPTTFGKEMAVYAARLGRALARITDAVDGLTGKLAGASGTWAAHTAAFPDVDWRSFAARFVDSLGLAYAEPTTQVNPCDDLTAVFDAVAGANGVLEDLAVDAWLYVSQRYLGQDAADGETGSSTMPHKVNPIDFENAEGNLAKANSDLGFLGDSLTTSRLQRDLSDSTVKRNIGAAFAHCLLAYRKLGDGLDAVTPNEAVLREDLRANPEVIGEAVQTILRREGHDDAYERVKALTRGERVSLDDFKELFASLDIDADTRDELLALTPERYVGVAADIARDA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	495 (423)
Sequences:	10586 (5383)
Seq/√Len:	261.7

ECOLI - PUR8 ASPA ARLY FUMC
BACSU - PUR8 FUMC ASPA ARLY
HALSA - Q9HS42 FUMC ARLY
SULSO - Q980P8 ARLY FUMC

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
86_A	96_V	3.708	1.00
95_L	154_W	3.476	1.00
79_A	104_R	3.324	1.00
87_D	272_R	3.277	1.00
413_V	416_E	3.228	1.00
178_T	240_V	3.173	1.00
360_D	389_A	2.979	1.00
83_L	276_S	2.848	1.00
186_R	233_L	2.797	1.00
83_L	100_R	2.777	1.00
472_T	475_E	2.767	1.00
73_A	175_G	2.764	1.00
305_N	357_A	2.738	1.00
415_R	419_R	2.660	1.00
189_R	230_G	2.641	1.00
191_D	405_D	2.631	1.00
177_I	297_V	2.600	1.00
353_N	396_A	2.560	1.00
182_T	237_T	2.544	1.00
191_D	401_G	2.528	1.00
69_A	391_A	2.510	1.00
218_F	409_P	2.456	1.00
272_R	275_D	2.414	1.00
182_T	233_L	2.402	1.00
242_G	296_A	2.388	1.00
195_F	198_D	2.273	1.00
302_A	361_L	2.270	1.00
436_E	475_E	2.263	1.00
184_E	398_R	2.238	1.00
201_D	411_E	2.232	1.00
187_G	401_G	2.198	1.00
327_D	408_T	2.110	1.00
186_R	237_T	2.097	1.00
86_A	93_L	2.066	1.00
356_K	385_N	2.056	1.00
416_E	420_A	2.052	1.00
401_G	405_D	2.043	1.00
53_R	146_H	2.008	1.00
457_D	465_S	1.987	1.00
189_R	233_L	1.953	1.00
413_V	417_D	1.937	1.00
92_P	95_L	1.935	1.00
194_S	405_D	1.931	1.00
194_S	198_D	1.928	1.00
272_R	276_S	1.909	1.00
105_D	143_L	1.888	1.00
447_A	451_G	1.884	1.00
460_K	477_L	1.867	1.00
143_L	147_A	1.863	1.00
191_D	404_L	1.863	1.00
306_G	358_N	1.850	1.00
117_L	145_E	1.849	1.00
184_E	394_L	1.849	1.00
312_A	350_A	1.842	1.00
238_D	242_G	1.832	1.00
245_G	274_V	1.820	1.00
233_L	237_T	1.818	1.00
97_G	101_T	1.811	1.00
185_L	304_A	1.765	1.00
235_R	296_A	1.765	1.00
238_D	241_D	1.755	1.00
76_E	175_G	1.754	1.00
93_L	97_G	1.747	1.00
440_D	443_E	1.744	1.00
271_A	275_D	1.743	1.00
447_A	466_L	1.737	1.00
193_V	230_G	1.731	1.00
98_D	148_P	1.715	1.00
79_A	100_R	1.712	1.00
295_T	368_L	1.710	1.00
281_Y	287_Q	1.681	1.00
199_Y	202_L	1.680	1.00
308_L	350_A	1.673	1.00
96_V	100_R	1.645	1.00
451_G	455_S	1.624	1.00
475_E	478_A	1.618	1.00
464_A	473_R	1.617	1.00
473_R	477_L	1.611	1.00
411_E	415_R	1.609	1.00
189_R	226_A	1.607	1.00
232_A	307_V	1.603	1.00
480_T	483_R	1.599	1.00
83_L	272_R	1.576	1.00
247_L	269_F	1.576	1.00
297_V	390_F	1.534	1.00
231_R	286_T	1.530	1.00
356_K	388_A	1.529	1.00
350_A	400_L	1.523	1.00
415_R	482_E	1.520	1.00
312_A	400_L	1.505	1.00
457_D	462_L	1.500	1.00
234_A	242_G	1.499	1.00
109_T	146_H	1.499	1.00
363_F	381_T	1.497	1.00
105_D	146_H	1.485	1.00
79_A	107_Y	1.461	1.00
196_A	226_A	1.450	1.00
268_S	271_A	1.447	1.00
173_V	386_I	1.438	1.00
184_E	401_G	1.436	1.00
302_A	365_G	1.427	1.00
249_G	287_Q	1.427	1.00
104_R	108_K	1.415	1.00
136_V	140_E	1.410	1.00
362_G	366_D	1.395	1.00
231_R	292_D	1.394	1.00
195_F	199_Y	1.390	1.00
410_N	413_V	1.380	1.00
189_R	229_L	1.374	1.00
84_A	272_R	1.369	1.00
72_R	76_E	1.368	1.00
291_C	379_D	1.367	1.00
241_D	280_A	1.361	1.00
239_A	300_A	1.354	1.00
182_T	240_V	1.341	1.00
298_F	364_L	1.337	1.00
412_A	416_E	1.332	1.00
458_D	461_E	1.331	1.00
299_D	303_G	1.316	1.00
311_L	400_L	1.309	1.00
222_M	225_Y	1.308	1.00
86_A	97_G	1.303	1.00
347_F	403_G	1.303	1.00
274_V	280_A	1.298	1.00
59_D	63_P	1.296	1.00
69_A	176_A	1.289	1.00
306_G	368_L	1.288	1.00
317_L	372_R	1.287	1.00
74_R	164_V	1.275	1.00
359_S	363_F	1.269	1.00
142_F	146_H	1.269	1.00
218_F	222_M	1.264	1.00
464_A	477_L	1.262	1.00
187_G	405_D	1.256	1.00
225_Y	374_Q	1.253	1.00
457_D	461_E	1.251	1.00
176_A	394_L	1.251	1.00
79_A	83_L	1.247	1.00
298_F	386_I	1.240	1.00
90_A	157_F	1.237	1.00
295_T	303_G	1.231	1.00
142_F	145_E	1.222	1.00
358_N	366_D	1.221	1.00
193_V	197_H	1.221	1.00
188_L	401_G	1.219	1.00
72_R	107_Y	1.212	1.00
75_V	106_A	1.212	1.00
185_L	229_L	1.205	1.00
218_F	414_L	1.204	1.00
173_V	297_V	1.200	1.00
202_L	411_E	1.196	1.00
100_R	104_R	1.194	1.00
180_V	394_L	1.192	1.00
144_R	152_H	1.191	1.00
440_D	468_I	1.182	1.00
199_Y	411_E	1.177	1.00
87_D	268_S	1.176	1.00
304_A	393_C	1.175	1.00
268_S	272_R	1.172	1.00
75_V	136_V	1.167	1.00
350_A	396_A	1.166	1.00
191_D	194_S	1.160	1.00
357_A	393_C	1.157	1.00
188_L	404_L	1.144	1.00
59_D	62_A	1.142	1.00
158_G	258_T	1.141	1.00
304_A	397_Y	1.138	1.00
326_Q	410_N	1.132	1.00
82_V	91_V	1.126	1.00
197_H	200_A	1.124	1.00
364_L	386_I	1.122	1.00
361_L	365_G	1.115	1.00
177_I	240_V	1.110	1.00
236_I	304_A	1.108	1.00
98_D	101_T	1.106	1.00
181_L	393_C	1.096	1.00
75_V	107_Y	1.094	1.00
294_L	386_I	1.093	1.00
354_L	358_N	1.089	1.00
72_R	111_D	1.086	1.00
182_T	186_R	1.081	1.00
305_N	393_C	1.078	1.00
192_L	311_L	1.076	1.00
80_E	276_S	1.074	1.00
104_R	107_Y	1.072	1.00
68_A	112_A	1.069	1.00
309_E	351_E	1.068	1.00
201_D	219_G	1.063	1.00
158_G	261_F	1.060	1.00
215_P	418_L	1.059	1.00
200_A	219_G	1.058	1.00
101_T	147_A	1.057	1.00
187_G	398_R	1.054	1.00
169_Y	386_I	1.047	1.00
184_E	187_G	1.046	1.00
298_F	389_A	1.045	1.00
169_Y	383_K	1.044	1.00
234_A	241_D	1.043	1.00
186_R	190_D	1.042	1.00
72_R	175_G	1.042	1.00
202_L	414_L	1.040	1.00
105_D	109_T	1.040	1.00
204_M	414_L	1.039	1.00
195_F	404_L	1.039	1.00
76_E	276_S	1.038	1.00
315_A	347_F	1.037	1.00
225_Y	311_L	1.037	1.00
193_V	226_A	1.036	1.00
77_V	164_V	1.034	1.00
48_S	63_P	1.030	1.00
188_L	229_L	1.029	1.00
174_D	279_L	1.027	1.00
315_A	407_V	1.026	1.00
185_L	233_L	1.021	1.00
200_A	217_T	1.017	1.00
451_G	462_L	1.014	1.00
250_A	337_T	1.009	1.00
223_A	283_E	1.009	1.00
238_D	296_A	1.009	1.00
167_L	245_G	1.007	1.00
297_V	386_I	1.007	1.00
300_A	304_A	1.006	1.00
169_Y	294_L	1.006	1.00
176_A	180_V	1.000	1.00
68_A	72_R	0.998	1.00
174_D	240_V	0.996	1.00
105_D	110_F	0.990	1.00
195_F	222_M	0.985	1.00
317_L	373_L	0.985	1.00
227_A	231_R	0.984	1.00
57_R	333_T	0.980	1.00
87_D	276_S	0.977	1.00
227_A	282_A	0.976	1.00
54_Y	59_D	0.971	1.00
53_R	111_D	0.968	1.00
174_D	178_T	0.965	1.00
101_T	105_D	0.960	1.00
308_L	400_L	0.956	1.00
74_R	77_V	0.953	1.00
356_K	392_H	0.952	1.00
327_D	406_A	0.951	1.00
73_A	171_L	0.950	1.00
121_I	141_Y	0.946	1.00
111_D	143_L	0.944	1.00
72_R	112_A	0.944	1.00
468_I	471_D	0.941	1.00
212_P	321_Q	0.940	1.00
98_D	102_A	0.940	1.00
216_T	251_S	0.939	1.00
207_R	212_P	0.939	1.00
451_G	457_D	0.937	1.00
177_I	236_I	0.935	1.00
234_A	238_D	0.934	1.00
447_A	462_L	0.932	1.00
49_P	52_G	0.930	1.00
206_A	216_T	0.929	1.00
97_G	100_R	0.924	1.00
308_L	397_Y	0.922	1.00
245_G	273_F	0.920	1.00
481_P	485_V	0.916	1.00
384_R	388_A	0.916	1.00
299_D	361_L	0.910	1.00
209_H	348_E	0.907	1.00
69_A	175_G	0.906	1.00
176_A	390_F	0.905	1.00
88_L	258_T	0.903	1.00
331_G	402_D	0.899	1.00
77_V	167_L	0.893	1.00
290_P	307_V	0.890	1.00
174_D	280_A	0.890	1.00
189_R	193_V	0.889	1.00
482_E	485_V	0.885	1.00
349_N	399_K	0.884	1.00
73_A	172_L	0.883	1.00
356_K	384_R	0.883	1.00
84_A	269_F	0.881	1.00
360_D	388_A	0.880	1.00
327_D	410_N	0.880	1.00
202_L	409_P	0.878	1.00
216_T	285_T	0.876	1.00
298_F	361_L	0.873	1.00
98_D	151_A	0.872	1.00
198_D	408_T	0.871	1.00
299_D	365_G	0.868	1.00
326_Q	408_T	0.867	1.00
76_E	107_Y	0.866	1.00
221_E	374_Q	0.865	1.00
203_P	418_L	0.863	1.00
262_P	267_R	0.861	1.00
220_K	284_P	0.856	1.00
196_A	223_A	0.853	1.00
210_G	317_L	0.852	1.00
116_D	120_R	0.850	1.00
150_R	153_S	0.845	0.99
301_V	393_C	0.843	0.99
481_P	484_Y	0.840	0.99
76_E	273_F	0.837	0.99
92_P	154_W	0.834	0.99
84_A	88_L	0.834	0.99
226_A	230_G	0.833	0.99
481_P	486_G	0.833	0.99
192_L	222_M	0.831	0.99
461_E	465_S	0.830	0.99
93_L	96_V	0.824	0.99
192_L	226_A	0.823	0.99
476_L	479_L	0.820	0.99
74_R	136_V	0.820	0.99
221_E	318_Y	0.818	0.99
105_D	111_D	0.817	0.99
460_K	473_R	0.816	0.99
190_D	194_S	0.816	0.99
474_D	478_A	0.815	0.99
447_A	465_S	0.815	0.99
289_N	374_Q	0.813	0.99
309_E	369_T	0.812	0.99
109_T	142_F	0.812	0.99
451_G	454_V	0.810	0.99
212_P	421_N	0.805	0.99
83_L	104_R	0.804	0.99
210_G	320_S	0.801	0.99
419_R	460_K	0.800	0.99
429_V	463_F	0.800	0.99
198_D	411_E	0.797	0.99
328_A	406_A	0.794	0.99
443_E	447_A	0.792	0.99
141_Y	145_E	0.792	0.99
66_S	399_K	0.791	0.99
66_S	377_L	0.790	0.99
460_K	464_A	0.789	0.99
103_L	140_E	0.787	0.99
94_E	97_G	0.786	0.99
109_T	112_A	0.785	0.99
432_I	436_E	0.782	0.99
229_L	397_Y	0.781	0.99
457_D	466_L	0.780	0.99
140_E	155_I	0.780	0.99
188_L	397_Y	0.779	0.99
244_T	293_D	0.778	0.99
83_L	87_D	0.777	0.99
355_A	363_F	0.777	0.99
192_L	404_L	0.777	0.99
247_L	273_F	0.775	0.99
90_A	258_T	0.774	0.99
463_F	466_L	0.772	0.99
306_G	365_G	0.772	0.99
102_A	147_A	0.770	0.99
56_G	328_A	0.769	0.99
178_T	279_L	0.767	0.99
87_D	93_L	0.765	0.99
231_R	244_T	0.763	0.99
191_D	195_F	0.761	0.99
60_A	63_P	0.761	0.99
363_F	385_N	0.761	0.99
123_T	134_H	0.760	0.99
81_Y	159_L	0.755	0.99
95_L	151_A	0.754	0.99
199_Y	409_P	0.754	0.99
121_I	138_A	0.754	0.99
418_L	481_P	0.753	0.99
91_V	95_L	0.752	0.99
292_D	307_V	0.751	0.99
106_A	112_A	0.750	0.99
65_V	176_A	0.750	0.99
296_A	299_D	0.749	0.99
185_L	397_Y	0.748	0.99
86_A	100_R	0.748	0.99
227_A	283_E	0.747	0.99
461_E	473_R	0.745	0.99
49_P	53_R	0.745	0.99
285_T	374_Q	0.740	0.99
70_L	165_N	0.738	0.99
367_S	381_T	0.738	0.99
99_E	151_A	0.737	0.99
177_I	243_L	0.737	0.99
329_A	406_A	0.737	0.99
55_S	62_A	0.735	0.99
432_I	435_R	0.734	0.99
294_L	364_L	0.733	0.99
403_G	407_V	0.732	0.99
205_L	322_R	0.731	0.98
205_L	418_L	0.730	0.98
356_K	360_D	0.730	0.98
235_R	292_D	0.730	0.98
246_K	287_Q	0.728	0.98
103_L	143_L	0.728	0.98
86_A	91_V	0.727	0.98
133_N	329_A	0.727	0.98
325_G	410_N	0.726	0.98
192_L	229_L	0.726	0.98
204_M	221_E	0.723	0.98
79_A	276_S	0.719	0.98
82_V	96_V	0.716	0.98
202_L	217_T	0.714	0.98
177_I	239_A	0.712	0.98
258_T	268_S	0.711	0.98
98_D	147_A	0.710	0.98
170_R	293_D	0.708	0.98
451_G	465_S	0.707	0.98
358_N	362_G	0.707	0.98
297_V	301_V	0.705	0.98
143_L	146_H	0.704	0.98
318_Y	373_L	0.704	0.98
228_R	307_V	0.703	0.98
103_L	106_A	0.703	0.98
228_R	289_N	0.703	0.98
443_E	466_L	0.701	0.98
447_A	450_R	0.700	0.98
450_R	454_V	0.699	0.98
286_T	292_D	0.698	0.98
217_T	485_V	0.698	0.98
409_P	414_L	0.697	0.98
239_A	243_L	0.695	0.98
358_N	365_G	0.693	0.98
109_T	114_D	0.692	0.98
295_T	364_L	0.691	0.98
462_L	466_L	0.691	0.98
203_P	485_V	0.688	0.98
229_L	232_A	0.688	0.98
286_T	307_V	0.688	0.98
143_L	155_I	0.686	0.98
207_R	321_Q	0.686	0.98
448_L	468_I	0.686	0.98
224_V	310_D	0.686	0.98
312_A	347_F	0.684	0.98
222_M	414_L	0.683	0.98
190_D	193_V	0.681	0.98
90_A	158_G	0.680	0.98
194_S	197_H	0.680	0.98
295_T	365_G	0.679	0.98
80_E	83_L	0.676	0.97
199_Y	218_F	0.676	0.97
429_V	476_L	0.675	0.97
201_D	482_E	0.672	0.97
106_A	140_E	0.672	0.97
397_Y	401_G	0.672	0.97
88_L	272_R	0.672	0.97
107_Y	111_D	0.671	0.97
451_G	468_I	0.670	0.97
122_E	134_H	0.668	0.97
108_K	112_A	0.667	0.97
186_R	230_G	0.667	0.97
313_V	351_E	0.667	0.97
202_L	415_R	0.666	0.97
455_S	466_L	0.666	0.97
355_A	367_S	0.666	0.97
232_A	303_G	0.666	0.97
88_L	268_S	0.666	0.97
187_G	191_D	0.666	0.97
413_V	420_A	0.665	0.97
91_V	157_F	0.662	0.97
385_N	388_A	0.662	0.97
62_A	346_D	0.661	0.97
178_T	237_T	0.657	0.97
447_A	467_D	0.656	0.97
355_A	366_D	0.656	0.97
228_R	290_P	0.654	0.97
452_E	462_L	0.654	0.97
197_H	201_D	0.653	0.97
181_L	390_F	0.652	0.97
150_R	439_D	0.650	0.97
309_E	366_D	0.649	0.97
111_D	114_D	0.648	0.97
447_A	457_D	0.648	0.97
186_R	189_R	0.647	0.97
323_Y	413_V	0.647	0.97
177_I	182_T	0.645	0.97
399_K	402_D	0.643	0.97
180_V	184_E	0.643	0.97
101_T	104_R	0.643	0.97
270_A	274_V	0.643	0.97
270_A	281_Y	0.641	0.97
303_G	368_L	0.641	0.97
232_A	235_R	0.640	0.97
362_G	365_G	0.640	0.97
419_R	458_D	0.639	0.96
235_R	242_G	0.638	0.96
412_A	415_R	0.638	0.96
102_A	105_D	0.636	0.96
295_T	299_D	0.635	0.96
315_A	400_L	0.634	0.96
79_A	96_V	0.633	0.96
464_A	476_L	0.632	0.96
95_L	98_D	0.631	0.96
323_Y	410_N	0.631	0.96
172_L	387_G	0.629	0.96
388_A	392_H	0.628	0.96
64_Y	69_A	0.626	0.96
82_V	155_I	0.624	0.96
331_G	406_A	0.624	0.96
173_V	390_F	0.624	0.96
386_I	390_F	0.624	0.96
274_V	279_L	0.622	0.96
235_R	238_D	0.620	0.96
229_L	308_L	0.620	0.96
462_L	465_S	0.618	0.96
95_L	99_E	0.617	0.96
204_M	216_T	0.615	0.96
121_I	131_A	0.615	0.96
115_A	142_F	0.615	0.96
451_G	466_L	0.613	0.96
151_A	154_W	0.612	0.96
172_L	390_F	0.611	0.95
94_E	98_D	0.611	0.95
458_D	462_L	0.610	0.95
120_R	123_T	0.610	0.95
312_A	351_E	0.609	0.95
357_A	389_A	0.606	0.95
62_A	66_S	0.606	0.95
195_F	407_V	0.604	0.95
87_D	262_P	0.604	0.95
236_I	300_A	0.601	0.95
411_E	414_L	0.601	0.95
244_T	281_Y	0.601	0.95
234_A	237_T	0.600	0.95
184_E	397_Y	0.599	0.95
418_L	423_E	0.598	0.95
350_A	403_G	0.598	0.95
181_L	301_V	0.597	0.95
357_A	392_H	0.596	0.95
66_S	402_D	0.594	0.95
363_F	382_V	0.593	0.95
117_L	121_I	0.593	0.95
302_A	306_G	0.592	0.95
309_E	370_T	0.590	0.95
353_N	392_H	0.590	0.95
65_V	332_E	0.589	0.95
446_K	450_R	0.588	0.94
239_A	297_V	0.587	0.94
154_W	157_F	0.586	0.94
350_A	354_L	0.586	0.94
230_G	234_A	0.585	0.94
227_A	230_G	0.585	0.94
193_V	196_A	0.585	0.94
301_V	304_A	0.585	0.94
84_A	268_S	0.585	0.94
311_L	404_L	0.584	0.94
123_T	131_A	0.581	0.94
432_I	475_E	0.581	0.94
241_D	244_T	0.579	0.94
229_L	304_A	0.578	0.94
196_A	200_A	0.577	0.94
443_E	450_R	0.576	0.94
71_M	110_F	0.575	0.94
83_L	96_V	0.575	0.94
363_F	367_S	0.572	0.94
105_D	147_A	0.571	0.94
225_Y	228_R	0.569	0.93
478_A	483_R	0.568	0.93
444_R	463_F	0.567	0.93
292_D	296_A	0.566	0.93
422_P	425_I	0.566	0.93
182_T	300_A	0.566	0.93
296_A	303_G	0.565	0.93
231_R	242_G	0.564	0.93
351_E	378_S	0.562	0.93
417_D	420_A	0.561	0.93
221_E	314_D	0.561	0.93
442_Y	446_K	0.560	0.93
346_D	403_G	0.558	0.93
161_S	246_K	0.558	0.93
82_V	100_R	0.553	0.92
92_P	96_V	0.553	0.92
247_L	262_P	0.552	0.92
76_E	80_E	0.552	0.92
175_G	178_T	0.552	0.92
271_A	274_V	0.551	0.92
214_T	251_S	0.551	0.92
75_V	112_A	0.550	0.92
188_L	191_D	0.549	0.92
216_T	220_K	0.548	0.92
209_H	377_L	0.548	0.92
202_L	219_G	0.547	0.92
216_T	253_T	0.545	0.92
448_L	451_G	0.545	0.92
244_T	282_A	0.545	0.92
483_R	486_G	0.545	0.92
239_A	296_A	0.542	0.92
82_V	99_E	0.541	0.92
185_L	236_I	0.540	0.92
303_G	307_V	0.539	0.92
237_T	241_D	0.539	0.92
222_M	407_V	0.537	0.91
86_A	94_E	0.536	0.91
223_A	226_A	0.535	0.91
246_K	288_V	0.534	0.91
439_D	443_E	0.534	0.91
332_E	345_I	0.534	0.91
359_S	362_G	0.533	0.91
73_A	76_E	0.533	0.91
428_A	483_R	0.533	0.91
474_D	477_L	0.532	0.91
234_A	244_T	0.531	0.91
77_V	247_L	0.530	0.91
301_V	389_A	0.530	0.91
81_Y	273_F	0.530	0.91
245_G	270_A	0.530	0.91
236_I	297_V	0.529	0.91
471_D	475_E	0.529	0.91
428_A	484_Y	0.528	0.91
76_E	277_L	0.526	0.91
199_Y	219_G	0.526	0.91
136_V	168_A	0.525	0.90
262_P	270_A	0.525	0.90
408_T	411_E	0.524	0.90
177_I	390_F	0.523	0.90
393_C	397_Y	0.523	0.90
108_K	111_D	0.522	0.90
231_R	296_A	0.519	0.90
147_A	151_A	0.519	0.90
117_L	120_R	0.519	0.90
467_D	470_A	0.516	0.90
444_R	466_L	0.516	0.90
171_L	273_F	0.514	0.90
77_V	168_A	0.513	0.89
315_A	404_L	0.513	0.89
457_D	463_F	0.512	0.89
257_H	431_T	0.510	0.89
148_P	152_H	0.509	0.89
117_L	135_D	0.507	0.89
68_A	75_V	0.506	0.89
183_P	187_G	0.506	0.89
460_K	476_L	0.505	0.89
157_F	434_R	0.505	0.89
214_T	255_A	0.505	0.89
444_R	462_L	0.504	0.89
174_D	243_L	0.503	0.88
195_F	218_F	0.503	0.88
383_K	387_G	0.503	0.88
99_E	147_A	0.502	0.88
206_A	252_G	0.502	0.88
204_M	318_Y	0.501	0.88
404_L	407_V	0.500	0.88
416_E	419_R	0.500	0.88
317_L	320_S	0.500	0.88

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2ptrA	4	0.897	100	0.26	Contact Map
3bhgA	4	0.8848	100	0.265	Contact Map
1re5A	4	0.8606	100	0.275	Contact Map
3c8tA	4	0.8263	100	0.281	Contact Map
4efcA	4	0.8909	100	0.281	Contact Map
4eeiA	4	0.8121	100	0.285	Contact Map
1q5nA	4	0.8364	100	0.286	Contact Map
1c3cA	4	0.8303	100	0.288	Contact Map
4mx2A	5	0.8727	100	0.289	Contact Map
2qgaB	4	0.8848	100	0.291	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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