Q9HS11 - HALSA - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

Q9HS11 - Phosphate ABC transporter permease

UniProt:	Q9HS11	Sequences: MSGDDLEAALTTRTQNAPSELLSRSFFFLCAALSIVTTIGLIALLATEAAKFFTFSAPLVGVDGATAGIVEFLTGTNWDPTNGSFGVLALVSATLMVMIGSSIIALPLGLGTATYLSEYASPRLRSVLKPALEILAGIPTVVYGFFAVIYITPALGTVLPGLSKFNMLSACVVVGIMIIPMVASISEDAMSAVPDELRQAGYGMGATKLEVSTGVVVPAALSGIFSSFILALSRAIGETMAVTIAAGSTARFLNIIDPGAYTESALPMTAAMVKLVKGDVTGGGLAYRSVFAIGATLFVITLVMNIVSDVIAHRFKEEY	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	319 (257)
Sequences:	68054 (44428)
Seq/√Len:	2771.4

ECOLI - POTH PSTA PSTC YDCU UGPA YCJO POTI CYSW POTB CYST YCJP POTC MALG YDCV THIP UGPE MALF YNJC MODB TAUC SSUC YEHY YEHW METI PROW PHNE YECS
BACSU - GANP YTEP MDXF AMYD YQGH ARAP LPLB YESP YURN YURM YQGI YESQ GANQ AMYC MDXG LPLC YTCP ARAQ SSUC OPUAB YVGM YTLD METP TCYB YXEN TCYL OPUCB OPUBD OPUCD OPUBB
HALSA - Q9HS11 Q9HML6 Q9HP01 Q9HP02 Q9HHQ7 Q9HMT4 Q9HPK3 Q9HHQ6 Q9HR05 Q9HNI9 Q9HML7 Q9HS12
SULSO - Q97UF3 Q97UZ0 Q97YY2 Q97YY3 Q97ZC1 Q97ZT6 Q97UY9 Q97ZT7 Q97UF4 Q97VC0 Q97ZC2 Q97Z98

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
210_E	214_G	4.178	1.00
92_S	96_M	3.186	1.00
202_Y	211_V	3.009	1.00
187_E	191_S	3.001	1.00
59_L	78_W	2.873	1.00
118_E	198_R	2.698	1.00
89_A	92_S	2.629	1.00
198_R	216_V	2.609	1.00
207_T	210_E	2.579	1.00
201_G	211_V	2.548	1.00
90_L	271_A	2.530	1.00
100_G	171_C	2.461	1.00
76_T	79_D	2.413	1.00
104_I	175_G	2.413	1.00
189_A	223_G	2.389	1.00
88_L	92_S	2.320	1.00
102_S	228_F	2.283	1.00
209_L	213_T	2.280	1.00
76_T	80_P	2.276	1.00
186_S	224_I	2.261	1.00
208_K	211_V	2.241	1.00
110_L	212_S	2.104	1.00
206_A	210_E	2.057	1.00
210_E	213_T	2.046	1.00
286_A	289_S	2.029	1.00
79_D	83_G	2.021	1.00
190_M	220_A	2.015	1.00
69_I	72_F	2.006	1.00
197_L	219_A	1.980	1.00
122_P	125_R	1.961	1.00
117_S	191_S	1.960	1.00
182_V	227_S	1.952	1.00
266_L	274_K	1.862	1.00
201_G	206_A	1.842	1.00
96_M	167_M	1.839	1.00
110_L	220_A	1.809	1.00
306_I	310_V	1.793	1.00
53_F	57_A	1.783	1.00
202_Y	208_K	1.766	1.00
89_A	93_A	1.763	1.00
109_G	182_V	1.726	1.00
106_L	228_F	1.725	1.00
198_R	211_V	1.695	1.00
98_M	232_L	1.693	1.00
116_L	183_A	1.675	1.00
129_K	187_E	1.669	1.00
57_A	61_G	1.654	1.00
110_L	186_S	1.650	1.00
96_M	100_G	1.643	1.00
112_T	183_A	1.605	1.00
101_S	235_A	1.576	1.00
198_R	202_Y	1.550	1.00
80_P	289_S	1.545	1.00
226_S	230_L	1.465	1.00
113_A	186_S	1.460	1.00
56_S	295_A	1.460	1.00
239_T	243_T	1.433	1.00
195_D	198_R	1.432	1.00
124_L	127_V	1.423	1.00
54_T	58_P	1.394	1.00
50_A	54_T	1.394	1.00
217_V	224_I	1.387	1.00
271_A	275_L	1.387	1.00
117_S	187_E	1.377	1.00
190_M	216_V	1.368	1.00
182_V	231_A	1.361	1.00
74_T	77_N	1.354	1.00
201_G	215_V	1.333	1.00
75_G	79_D	1.327	1.00
38_T	42_I	1.325	1.00
186_S	227_S	1.319	1.00
118_E	195_D	1.317	1.00
241_A	245_A	1.308	1.00
105_A	231_A	1.306	1.00
107_P	111_G	1.302	1.00
119_Y	122_P	1.300	1.00
121_S	125_R	1.287	1.00
173_V	245_A	1.279	1.00
86_G	89_A	1.270	1.00
195_D	199_Q	1.266	1.00
207_T	211_V	1.227	1.00
267_P	270_A	1.227	1.00
114_T	190_M	1.223	1.00
248_S	251_R	1.222	1.00
196_E	199_Q	1.222	1.00
151_I	169_S	1.218	1.00
78_W	295_A	1.215	1.00
110_L	224_I	1.212	1.00
80_P	83_G	1.207	1.00
249_T	252_F	1.202	1.00
239_T	273_V	1.196	1.00
170_A	242_V	1.194	1.00
193_V	219_A	1.193	1.00
94_T	268_M	1.189	1.00
252_F	266_L	1.167	1.00
100_G	103_I	1.157	1.00
127_V	130_P	1.138	1.00
97_V	267_P	1.133	1.00
275_L	286_A	1.131	1.00
186_S	223_G	1.127	1.00
103_I	107_P	1.126	1.00
93_A	96_M	1.119	1.00
106_L	224_I	1.118	1.00
51_K	55_F	1.117	1.00
55_F	295_A	1.091	1.00
221_L	225_F	1.087	1.00
275_L	284_G	1.083	1.00
127_V	131_A	1.079	1.00
114_T	212_S	1.075	1.00
198_R	208_K	1.072	1.00
165_F	168_L	1.062	1.00
179_I	183_A	1.052	1.00
185_I	227_S	1.049	1.00
101_S	174_V	1.040	1.00
42_I	46_A	1.039	1.00
100_G	104_I	1.029	1.00
266_L	270_A	1.029	1.00
58_P	291_F	1.027	1.00
114_T	208_K	1.026	1.00
219_A	222_S	1.026	1.00
168_L	172_V	1.026	1.00
117_S	190_M	1.026	1.00
154_A	157_T	1.025	1.00
54_T	57_A	1.023	1.00
95_L	99_I	1.021	1.00
104_I	171_C	1.018	1.00
31_A	35_I	1.010	1.00
44_L	51_K	0.997	1.00
271_A	293_I	0.994	1.00
238_E	241_A	0.991	1.00
111_G	115_Y	0.990	1.00
62_V	65_A	0.980	1.00
276_V	290_V	0.977	1.00
125_R	191_S	0.974	1.00
211_V	214_G	0.969	1.00
167_M	171_C	0.967	1.00
206_A	211_V	0.967	1.00
101_S	105_A	0.967	1.00
91_V	268_M	0.963	1.00
45_L	49_A	0.959	1.00
174_V	235_A	0.953	1.00
147_A	245_A	0.947	1.00
80_P	84_S	0.945	1.00
189_A	220_A	0.942	1.00
164_K	168_L	0.940	1.00
307_V	311_I	0.938	1.00
99_I	103_I	0.935	1.00
82_N	88_L	0.933	1.00
77_N	288_R	0.928	1.00
271_A	274_K	0.924	1.00
123_R	126_S	0.924	1.00
238_E	242_V	0.924	1.00
212_S	217_V	0.913	1.00
157_T	168_L	0.911	1.00
101_S	171_C	0.910	1.00
307_V	310_V	0.903	1.00
87_V	293_I	0.895	1.00
96_M	168_L	0.892	1.00
97_V	167_M	0.890	1.00
171_C	175_G	0.890	1.00
213_T	217_V	0.885	1.00
32_A	36_V	0.885	1.00
65_A	68_G	0.885	1.00
44_L	48_E	0.884	1.00
149_I	153_P	0.884	1.00
113_A	190_M	0.884	1.00
96_M	99_I	0.882	1.00
91_V	95_L	0.880	1.00
221_L	224_I	0.879	1.00
182_V	186_S	0.878	1.00
104_I	107_P	0.875	1.00
58_P	61_G	0.872	1.00
113_A	117_S	0.872	1.00
147_A	173_V	0.872	1.00
93_A	167_M	0.865	1.00
109_G	183_A	0.858	1.00
45_L	48_E	0.858	1.00
266_L	271_A	0.856	1.00
35_I	39_I	0.853	1.00
105_A	109_G	0.848	1.00
220_A	223_G	0.846	1.00
289_S	293_I	0.844	1.00
115_Y	122_P	0.843	1.00
55_F	291_F	0.836	1.00
34_S	38_T	0.833	1.00
231_A	235_A	0.833	1.00
103_I	228_F	0.830	1.00
126_S	129_K	0.829	1.00
133_E	184_S	0.826	1.00
164_K	167_M	0.825	1.00
33_L	37_T	0.825	1.00
84_S	88_L	0.823	1.00
65_A	69_I	0.820	1.00
80_P	286_A	0.819	1.00
116_L	129_K	0.819	1.00
186_S	220_A	0.819	1.00
150_Y	155_L	0.819	1.00
144_G	244_I	0.817	1.00
197_L	215_V	0.815	1.00
82_N	85_F	0.811	1.00
243_T	270_A	0.808	1.00
148_V	152_T	0.808	1.00
37_T	41_L	0.804	1.00
81_T	296_T	0.801	1.00
303_V	307_V	0.795	1.00
212_S	216_V	0.794	1.00
242_V	267_P	0.792	1.00
105_A	178_I	0.791	1.00
173_V	241_A	0.789	1.00
116_L	128_L	0.786	1.00
113_A	183_A	0.784	1.00
140_T	177_M	0.783	1.00
152_T	164_K	0.780	1.00
100_G	175_G	0.779	1.00
92_S	95_L	0.778	1.00
246_A	251_R	0.775	1.00
97_V	174_V	0.774	1.00
287_Y	290_V	0.768	1.00
90_L	93_A	0.765	1.00
48_E	51_K	0.764	1.00
169_S	173_V	0.761	1.00
63_D	67_A	0.761	1.00
144_G	240_M	0.761	1.00
68_G	71_E	0.759	1.00
193_V	220_A	0.756	1.00
208_K	212_S	0.751	1.00
66_T	69_I	0.749	1.00
238_E	267_P	0.748	1.00
272_M	293_I	0.744	1.00
60_V	74_T	0.741	1.00
274_K	283_G	0.741	1.00
62_V	71_E	0.739	1.00
98_M	102_S	0.737	1.00
105_A	182_V	0.735	1.00
195_D	202_Y	0.734	1.00
211_V	216_V	0.733	1.00
39_I	42_I	0.732	1.00
224_I	227_S	0.729	1.00
72_F	75_G	0.724	1.00
165_F	248_S	0.724	1.00
56_S	60_V	0.721	1.00
186_S	190_M	0.720	1.00
78_W	292_A	0.718	1.00
106_L	186_S	0.718	1.00
94_T	269_T	0.716	1.00
60_V	73_L	0.715	1.00
168_L	171_C	0.714	1.00
170_A	246_A	0.713	1.00
275_L	293_I	0.713	1.00
275_L	289_S	0.712	1.00
136_A	180_P	0.703	1.00
50_A	53_F	0.701	1.00
247_G	250_A	0.700	1.00
169_S	245_A	0.694	1.00
301_T	305_N	0.691	1.00
133_E	136_A	0.691	1.00
166_N	169_S	0.691	1.00
69_I	73_L	0.690	1.00
291_F	295_A	0.690	1.00
36_V	40_G	0.688	1.00
109_G	186_S	0.683	1.00
97_V	170_A	0.682	1.00
116_L	187_E	0.680	1.00
112_T	179_I	0.674	1.00
270_A	274_K	0.674	1.00
119_Y	125_R	0.674	1.00
105_A	235_A	0.673	1.00
90_L	268_M	0.673	1.00
223_G	227_S	0.669	1.00
224_I	228_F	0.665	1.00
102_S	232_L	0.665	1.00
273_V	276_V	0.664	1.00
62_V	66_T	0.661	1.00
88_L	91_V	0.660	1.00
165_F	169_S	0.657	1.00
140_T	240_M	0.654	1.00
102_S	106_L	0.649	1.00
32_A	35_I	0.647	1.00
242_V	270_A	0.646	1.00
97_V	171_C	0.644	1.00
81_T	289_S	0.643	1.00
167_M	251_R	0.643	1.00
124_L	128_L	0.642	1.00
79_D	82_N	0.642	1.00
36_V	39_I	0.640	1.00
49_A	53_F	0.640	1.00
40_G	44_L	0.639	1.00
302_L	306_I	0.639	1.00
55_F	294_G	0.637	1.00
185_I	223_G	0.636	1.00
200_A	204_M	0.634	1.00
61_G	70_V	0.634	1.00
270_A	273_V	0.632	1.00
206_A	214_G	0.632	1.00
207_T	213_T	0.629	1.00
216_V	219_A	0.624	1.00
81_T	293_I	0.624	1.00
287_Y	291_F	0.623	1.00
35_I	38_T	0.618	1.00
108_L	179_I	0.615	1.00
147_A	150_Y	0.613	1.00
85_F	88_L	0.610	1.00
170_A	174_V	0.607	1.00
149_I	152_T	0.606	1.00
269_T	297_L	0.605	1.00
233_S	237_G	0.605	1.00
57_A	60_V	0.603	1.00
141_V	244_I	0.599	1.00
102_S	235_A	0.599	1.00
94_T	236_I	0.597	1.00
105_A	175_G	0.595	1.00
300_I	303_V	0.595	1.00
67_A	71_E	0.594	1.00
246_A	250_A	0.593	1.00
115_Y	119_Y	0.592	1.00
178_I	231_A	0.588	1.00
77_N	80_P	0.587	1.00
178_I	234_R	0.586	1.00
97_V	101_S	0.585	1.00
85_F	89_A	0.585	1.00
268_M	297_L	0.585	1.00
122_P	128_L	0.584	1.00
101_S	175_G	0.584	1.00
291_F	294_G	0.584	1.00
129_K	184_S	0.584	1.00
240_M	243_T	0.583	1.00
136_A	181_M	0.582	1.00
75_G	78_W	0.580	1.00
43_A	47_T	0.579	1.00
283_G	286_A	0.579	1.00
174_V	242_V	0.579	1.00
84_S	289_S	0.579	1.00
108_L	175_G	0.578	1.00
73_L	76_T	0.578	1.00
193_V	198_R	0.578	1.00
240_M	244_I	0.577	1.00
123_R	127_V	0.577	1.00
31_A	34_S	0.574	1.00
211_V	215_V	0.573	1.00
143_Y	176_I	0.572	1.00
98_M	235_A	0.571	1.00
59_L	292_A	0.570	1.00
148_V	164_K	0.567	1.00
128_L	132_L	0.566	1.00
112_T	132_L	0.566	1.00
61_G	72_F	0.565	1.00
140_T	144_G	0.564	1.00
113_A	187_E	0.563	1.00
288_R	291_F	0.559	1.00
225_F	228_F	0.557	1.00
67_A	70_V	0.556	1.00
131_A	135_L	0.556	1.00
92_S	167_M	0.554	1.00
34_S	37_T	0.548	1.00
174_V	238_E	0.547	1.00
126_S	130_P	0.545	1.00
64_G	67_A	0.544	1.00
98_M	236_I	0.544	1.00
41_L	45_L	0.539	1.00
59_L	295_A	0.536	1.00
286_A	290_V	0.535	1.00
200_A	203_G	0.534	1.00
51_K	56_S	0.533	1.00
106_L	110_L	0.532	1.00
114_T	216_V	0.531	1.00
47_T	51_K	0.530	1.00
269_T	272_M	0.529	1.00
213_T	216_V	0.524	1.00
61_G	71_E	0.523	1.00
228_F	231_A	0.522	1.00
151_I	164_K	0.521	1.00
234_R	237_G	0.520	1.00
65_A	71_E	0.519	1.00
199_Q	202_Y	0.517	1.00
112_T	115_Y	0.517	1.00
235_A	238_E	0.516	1.00
227_S	231_A	0.515	1.00
93_A	267_P	0.515	1.00
63_D	66_T	0.514	1.00
130_P	134_I	0.513	1.00
231_A	234_R	0.512	1.00
133_E	137_G	0.512	1.00
91_V	296_T	0.511	1.00
273_V	277_K	0.505	1.00
83_G	86_G	0.503	1.00
96_M	171_C	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2onkC	2	0.7774	100	0.348	Contact Map
3d31C	2	0.7586	100	0.377	Contact Map
4tquM	1	0.8433	100	0.387	Contact Map
3rlfG	1	0.837	100	0.419	Contact Map
3rlfF	1	0.9279	100	0.425	Contact Map
4tquN	1	0.8307	100	0.441	Contact Map
4ymuD	2	0.6708	100	0.528	Contact Map
3tuiA	2	0.6583	99.9	0.54	Contact Map
2m8rA	1	0.1693	20.7	0.946	Contact Map
2kogA	1	0.1693	11.9	0.952	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0101 seconds.