GREMLIN Database
Q9HS11 - Phosphate ABC transporter permease
UniProt: Q9HS11 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 319 (257)
Sequences: 68054 (44428)
Seq/√Len: 2771.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
210_E214_G4.1781.00
92_S96_M3.1861.00
202_Y211_V3.0091.00
187_E191_S3.0011.00
59_L78_W2.8731.00
118_E198_R2.6981.00
89_A92_S2.6291.00
198_R216_V2.6091.00
207_T210_E2.5791.00
201_G211_V2.5481.00
90_L271_A2.5301.00
100_G171_C2.4611.00
76_T79_D2.4131.00
104_I175_G2.4131.00
189_A223_G2.3891.00
88_L92_S2.3201.00
102_S228_F2.2831.00
209_L213_T2.2801.00
76_T80_P2.2761.00
186_S224_I2.2611.00
208_K211_V2.2411.00
110_L212_S2.1041.00
206_A210_E2.0571.00
210_E213_T2.0461.00
286_A289_S2.0291.00
79_D83_G2.0211.00
190_M220_A2.0151.00
69_I72_F2.0061.00
197_L219_A1.9801.00
122_P125_R1.9611.00
117_S191_S1.9601.00
182_V227_S1.9521.00
266_L274_K1.8621.00
201_G206_A1.8421.00
96_M167_M1.8391.00
110_L220_A1.8091.00
306_I310_V1.7931.00
53_F57_A1.7831.00
202_Y208_K1.7661.00
89_A93_A1.7631.00
109_G182_V1.7261.00
106_L228_F1.7251.00
198_R211_V1.6951.00
98_M232_L1.6931.00
116_L183_A1.6751.00
129_K187_E1.6691.00
57_A61_G1.6541.00
110_L186_S1.6501.00
96_M100_G1.6431.00
112_T183_A1.6051.00
101_S235_A1.5761.00
198_R202_Y1.5501.00
80_P289_S1.5451.00
226_S230_L1.4651.00
113_A186_S1.4601.00
56_S295_A1.4601.00
239_T243_T1.4331.00
195_D198_R1.4321.00
124_L127_V1.4231.00
54_T58_P1.3941.00
50_A54_T1.3941.00
217_V224_I1.3871.00
271_A275_L1.3871.00
117_S187_E1.3771.00
190_M216_V1.3681.00
182_V231_A1.3611.00
74_T77_N1.3541.00
201_G215_V1.3331.00
75_G79_D1.3271.00
38_T42_I1.3251.00
186_S227_S1.3191.00
118_E195_D1.3171.00
241_A245_A1.3081.00
105_A231_A1.3061.00
107_P111_G1.3021.00
119_Y122_P1.3001.00
121_S125_R1.2871.00
173_V245_A1.2791.00
86_G89_A1.2701.00
195_D199_Q1.2661.00
207_T211_V1.2271.00
267_P270_A1.2271.00
114_T190_M1.2231.00
248_S251_R1.2221.00
196_E199_Q1.2221.00
151_I169_S1.2181.00
78_W295_A1.2151.00
110_L224_I1.2121.00
80_P83_G1.2071.00
249_T252_F1.2021.00
239_T273_V1.1961.00
170_A242_V1.1941.00
193_V219_A1.1931.00
94_T268_M1.1891.00
252_F266_L1.1671.00
100_G103_I1.1571.00
127_V130_P1.1381.00
97_V267_P1.1331.00
275_L286_A1.1311.00
186_S223_G1.1271.00
103_I107_P1.1261.00
93_A96_M1.1191.00
106_L224_I1.1181.00
51_K55_F1.1171.00
55_F295_A1.0911.00
221_L225_F1.0871.00
275_L284_G1.0831.00
127_V131_A1.0791.00
114_T212_S1.0751.00
198_R208_K1.0721.00
165_F168_L1.0621.00
179_I183_A1.0521.00
185_I227_S1.0491.00
101_S174_V1.0401.00
42_I46_A1.0391.00
100_G104_I1.0291.00
266_L270_A1.0291.00
58_P291_F1.0271.00
114_T208_K1.0261.00
219_A222_S1.0261.00
168_L172_V1.0261.00
117_S190_M1.0261.00
154_A157_T1.0251.00
54_T57_A1.0231.00
95_L99_I1.0211.00
104_I171_C1.0181.00
31_A35_I1.0101.00
44_L51_K0.9971.00
271_A293_I0.9941.00
238_E241_A0.9911.00
111_G115_Y0.9901.00
62_V65_A0.9801.00
276_V290_V0.9771.00
125_R191_S0.9741.00
211_V214_G0.9691.00
167_M171_C0.9671.00
206_A211_V0.9671.00
101_S105_A0.9671.00
91_V268_M0.9631.00
45_L49_A0.9591.00
174_V235_A0.9531.00
147_A245_A0.9471.00
80_P84_S0.9451.00
189_A220_A0.9421.00
164_K168_L0.9401.00
307_V311_I0.9381.00
99_I103_I0.9351.00
82_N88_L0.9331.00
77_N288_R0.9281.00
271_A274_K0.9241.00
123_R126_S0.9241.00
238_E242_V0.9241.00
212_S217_V0.9131.00
157_T168_L0.9111.00
101_S171_C0.9101.00
307_V310_V0.9031.00
87_V293_I0.8951.00
96_M168_L0.8921.00
97_V167_M0.8901.00
171_C175_G0.8901.00
213_T217_V0.8851.00
32_A36_V0.8851.00
65_A68_G0.8851.00
44_L48_E0.8841.00
149_I153_P0.8841.00
113_A190_M0.8841.00
96_M99_I0.8821.00
91_V95_L0.8801.00
221_L224_I0.8791.00
182_V186_S0.8781.00
104_I107_P0.8751.00
58_P61_G0.8721.00
113_A117_S0.8721.00
147_A173_V0.8721.00
93_A167_M0.8651.00
109_G183_A0.8581.00
45_L48_E0.8581.00
266_L271_A0.8561.00
35_I39_I0.8531.00
105_A109_G0.8481.00
220_A223_G0.8461.00
289_S293_I0.8441.00
115_Y122_P0.8431.00
55_F291_F0.8361.00
34_S38_T0.8331.00
231_A235_A0.8331.00
103_I228_F0.8301.00
126_S129_K0.8291.00
133_E184_S0.8261.00
164_K167_M0.8251.00
33_L37_T0.8251.00
84_S88_L0.8231.00
65_A69_I0.8201.00
80_P286_A0.8191.00
116_L129_K0.8191.00
186_S220_A0.8191.00
150_Y155_L0.8191.00
144_G244_I0.8171.00
197_L215_V0.8151.00
82_N85_F0.8111.00
243_T270_A0.8081.00
148_V152_T0.8081.00
37_T41_L0.8041.00
81_T296_T0.8011.00
303_V307_V0.7951.00
212_S216_V0.7941.00
242_V267_P0.7921.00
105_A178_I0.7911.00
173_V241_A0.7891.00
116_L128_L0.7861.00
113_A183_A0.7841.00
140_T177_M0.7831.00
152_T164_K0.7801.00
100_G175_G0.7791.00
92_S95_L0.7781.00
246_A251_R0.7751.00
97_V174_V0.7741.00
287_Y290_V0.7681.00
90_L93_A0.7651.00
48_E51_K0.7641.00
169_S173_V0.7611.00
63_D67_A0.7611.00
144_G240_M0.7611.00
68_G71_E0.7591.00
193_V220_A0.7561.00
208_K212_S0.7511.00
66_T69_I0.7491.00
238_E267_P0.7481.00
272_M293_I0.7441.00
60_V74_T0.7411.00
274_K283_G0.7411.00
62_V71_E0.7391.00
98_M102_S0.7371.00
105_A182_V0.7351.00
195_D202_Y0.7341.00
211_V216_V0.7331.00
39_I42_I0.7321.00
224_I227_S0.7291.00
72_F75_G0.7241.00
165_F248_S0.7241.00
56_S60_V0.7211.00
186_S190_M0.7201.00
78_W292_A0.7181.00
106_L186_S0.7181.00
94_T269_T0.7161.00
60_V73_L0.7151.00
168_L171_C0.7141.00
170_A246_A0.7131.00
275_L293_I0.7131.00
275_L289_S0.7121.00
136_A180_P0.7031.00
50_A53_F0.7011.00
247_G250_A0.7001.00
169_S245_A0.6941.00
301_T305_N0.6911.00
133_E136_A0.6911.00
166_N169_S0.6911.00
69_I73_L0.6901.00
291_F295_A0.6901.00
36_V40_G0.6881.00
109_G186_S0.6831.00
97_V170_A0.6821.00
116_L187_E0.6801.00
112_T179_I0.6741.00
270_A274_K0.6741.00
119_Y125_R0.6741.00
105_A235_A0.6731.00
90_L268_M0.6731.00
223_G227_S0.6691.00
224_I228_F0.6651.00
102_S232_L0.6651.00
273_V276_V0.6641.00
62_V66_T0.6611.00
88_L91_V0.6601.00
165_F169_S0.6571.00
140_T240_M0.6541.00
102_S106_L0.6491.00
32_A35_I0.6471.00
242_V270_A0.6461.00
97_V171_C0.6441.00
81_T289_S0.6431.00
167_M251_R0.6431.00
124_L128_L0.6421.00
79_D82_N0.6421.00
36_V39_I0.6401.00
49_A53_F0.6401.00
40_G44_L0.6391.00
302_L306_I0.6391.00
55_F294_G0.6371.00
185_I223_G0.6361.00
200_A204_M0.6341.00
61_G70_V0.6341.00
270_A273_V0.6321.00
206_A214_G0.6321.00
207_T213_T0.6291.00
216_V219_A0.6241.00
81_T293_I0.6241.00
287_Y291_F0.6231.00
35_I38_T0.6181.00
108_L179_I0.6151.00
147_A150_Y0.6131.00
85_F88_L0.6101.00
170_A174_V0.6071.00
149_I152_T0.6061.00
269_T297_L0.6051.00
233_S237_G0.6051.00
57_A60_V0.6031.00
141_V244_I0.5991.00
102_S235_A0.5991.00
94_T236_I0.5971.00
105_A175_G0.5951.00
300_I303_V0.5951.00
67_A71_E0.5941.00
246_A250_A0.5931.00
115_Y119_Y0.5921.00
178_I231_A0.5881.00
77_N80_P0.5871.00
178_I234_R0.5861.00
97_V101_S0.5851.00
85_F89_A0.5851.00
268_M297_L0.5851.00
122_P128_L0.5841.00
101_S175_G0.5841.00
291_F294_G0.5841.00
129_K184_S0.5841.00
240_M243_T0.5831.00
136_A181_M0.5821.00
75_G78_W0.5801.00
43_A47_T0.5791.00
283_G286_A0.5791.00
174_V242_V0.5791.00
84_S289_S0.5791.00
108_L175_G0.5781.00
73_L76_T0.5781.00
193_V198_R0.5781.00
240_M244_I0.5771.00
123_R127_V0.5771.00
31_A34_S0.5741.00
211_V215_V0.5731.00
143_Y176_I0.5721.00
98_M235_A0.5711.00
59_L292_A0.5701.00
148_V164_K0.5671.00
128_L132_L0.5661.00
112_T132_L0.5661.00
61_G72_F0.5651.00
140_T144_G0.5641.00
113_A187_E0.5631.00
288_R291_F0.5591.00
225_F228_F0.5571.00
67_A70_V0.5561.00
131_A135_L0.5561.00
92_S167_M0.5541.00
34_S37_T0.5481.00
174_V238_E0.5471.00
126_S130_P0.5451.00
64_G67_A0.5441.00
98_M236_I0.5441.00
41_L45_L0.5391.00
59_L295_A0.5361.00
286_A290_V0.5351.00
200_A203_G0.5341.00
51_K56_S0.5331.00
106_L110_L0.5321.00
114_T216_V0.5311.00
47_T51_K0.5301.00
269_T272_M0.5291.00
213_T216_V0.5241.00
61_G71_E0.5231.00
228_F231_A0.5221.00
151_I164_K0.5211.00
234_R237_G0.5201.00
65_A71_E0.5191.00
199_Q202_Y0.5171.00
112_T115_Y0.5171.00
235_A238_E0.5161.00
227_S231_A0.5151.00
93_A267_P0.5151.00
63_D66_T0.5141.00
130_P134_I0.5131.00
231_A234_R0.5121.00
133_E137_G0.5121.00
91_V296_T0.5111.00
273_V277_K0.5051.00
83_G86_G0.5031.00
96_M171_C0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2onkC 2 0.7774 100 0.348 Contact Map
3d31C 2 0.7586 100 0.377 Contact Map
4tquM 1 0.8433 100 0.387 Contact Map
3rlfG 1 0.837 100 0.419 Contact Map
3rlfF 1 0.9279 100 0.425 Contact Map
4tquN 1 0.8307 100 0.441 Contact Map
4ymuD 2 0.6708 100 0.528 Contact Map
3tuiA 2 0.6583 99.9 0.54 Contact Map
2m8rA 1 0.1693 20.7 0.946 Contact Map
2kogA 1 0.1693 11.9 0.952 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0103 seconds.