Q9HS01 - HALSA - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

Q9HS01 - Uncharacterized protein

UniProt:	Q9HS01	Sequences: MSDKHDVIVAGAGPAGAQCARDLAERGYDVVVLEAEPEDEFPRQSNKSTAGTFASMMGAFGVPDDVVMQYTDDVVLESPHEYFVQDQPGAVLEFAEFKQWLVAAGEQQGAEYRFEARVNNPITEGGEIVGVKYDGDEEVYGDIIIDATGPAAPLAKKLGVTDLRRSNQAIGIEWEMENVAVDHEGYADLSDAMMLRLDHDLAPGGYSWIFHTGADTAKVGICYIQNESYQRFGDASKSIDDHLDYWMETDPRLADATKLAGKQHRGSAHIQLPANFSTDNFMAIGDTVPTVDPLWGEGIHKCMESARAAAITADRCFMGDDRDTSADALSIYDDLWHKRVAPNARMRLTMTQLLYLASNERYDRLMSDLQTADVGTLSGANEGGLRSLLEFVHTEDVPLLARFARDRLRA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	410 (334)
Sequences:	26615 (20214)
Seq/√Len:	1106.0

ECOLI - UBIF MHPA UBII UBIH FIXC YDIS YGCN CBRA
BACSU - YHJG YETM
HALSA - Q9HS01 Q9HS24 Q9HQE5 Q9HMA0
SULSO - Q97V59 Q97V18 Q97W83 Q97W89 Q97ZK8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
31_V	113_R	3.963	1.00
35_A	117_R	3.670	1.00
15_A	302_C	3.609	1.00
6_D	142_D	3.218	1.00
333_D	337_H	3.209	1.00
6_D	29_D	3.192	1.00
8_I	141_G	3.174	1.00
120_N	157_K	2.698	1.00
19_C	145_I	2.622	1.00
5_H	31_V	2.591	1.00
65_D	103_A	2.526	1.00
33_L	139_V	2.506	1.00
8_I	33_L	2.485	1.00
104_A	107_Q	2.451	1.00
22_D	310_A	2.442	1.00
116_A	135_G	2.437	1.00
26_R	314_D	2.411	1.00
85_Q	88_P	2.299	1.00
122_I	130_G	2.180	1.00
99_Q	103_A	2.172	1.00
120_N	132_K	2.122	1.00
15_A	284_I	2.113	1.00
8_I	131_V	2.079	1.00
18_Q	303_M	2.060	1.00
312_T	335_L	2.047	1.00
117_R	134_D	2.039	1.00
146_D	154_L	2.031	1.00
130_G	138_E	2.009	1.00
132_K	138_E	1.996	1.00
113_R	116_A	1.981	1.00
130_G	140_Y	1.963	1.00
29_D	111_E	1.945	1.00
7_V	28_Y	1.936	1.00
235_A	238_S	1.927	1.00
240_D	244_D	1.921	1.00
104_A	108_Q	1.905	1.00
277_S	330_S	1.871	1.00
147_A	284_I	1.816	1.00
146_D	283_A	1.783	1.00
21_R	104_A	1.773	1.00
121_P	144_I	1.768	1.00
56_M	307_R	1.768	1.00
58_G	63_P	1.763	1.00
65_D	104_A	1.746	1.00
116_A	133_Y	1.723	1.00
124_E	140_Y	1.700	1.00
337_H	341_A	1.688	1.00
105_G	110_A	1.684	1.00
277_S	282_M	1.679	1.00
37_P	115_E	1.671	1.00
306_A	310_A	1.665	1.00
7_V	23_L	1.663	1.00
275_N	278_T	1.649	1.00
312_T	331_I	1.640	1.00
8_I	139_V	1.634	1.00
122_I	132_K	1.629	1.00
53_F	300_H	1.623	1.00
24_A	110_A	1.601	1.00
31_V	139_V	1.597	1.00
177_E	257_T	1.596	1.00
123_T	278_T	1.590	1.00
143_I	329_L	1.581	1.00
20_A	32_V	1.576	1.00
6_D	31_V	1.570	1.00
65_D	68_M	1.567	1.00
64_D	68_M	1.566	1.00
308_A	312_T	1.565	1.00
118_V	131_V	1.564	1.00
28_Y	314_D	1.560	1.00
305_S	336_W	1.544	1.00
133_Y	136_D	1.543	1.00
65_D	107_Q	1.535	1.00
148_T	152_A	1.521	1.00
25_E	108_Q	1.504	1.00
124_E	127_E	1.499	1.00
145_I	284_I	1.493	1.00
127_E	140_Y	1.481	1.00
311_I	335_L	1.473	1.00
133_Y	139_V	1.470	1.00
276_F	333_D	1.462	1.00
119_N	134_D	1.458	1.00
102_V	114_F	1.455	1.00
308_A	335_L	1.451	1.00
19_C	306_A	1.444	1.00
276_F	340_V	1.433	1.00
238_S	241_D	1.426	1.00
304_E	339_R	1.424	1.00
158_L	281_F	1.423	1.00
275_N	333_D	1.419	1.00
282_M	309_A	1.406	1.00
59_A	307_R	1.402	1.00
270_I	348_L	1.382	1.00
256_A	259_L	1.371	1.00
153_P	157_K	1.365	1.00
119_N	132_K	1.352	1.00
9_V	19_C	1.352	1.00
21_R	25_E	1.348	1.00
237_K	241_D	1.347	1.00
33_L	133_Y	1.347	1.00
241_D	245_Y	1.347	1.00
21_R	105_G	1.338	1.00
124_E	130_G	1.336	1.00
14_P	299_I	1.334	1.00
312_T	328_A	1.326	1.00
289_P	305_S	1.298	1.00
81_E	84_V	1.297	1.00
145_I	282_M	1.296	1.00
133_Y	137_E	1.295	1.00
237_K	240_D	1.293	1.00
22_D	60_F	1.279	1.00
6_D	28_Y	1.278	1.00
118_V	154_L	1.272	1.00
21_R	108_Q	1.270	1.00
102_V	106_E	1.267	1.00
53_F	303_M	1.251	1.00
5_H	8_I	1.249	1.00
255_D	258_K	1.242	1.00
63_P	67_V	1.240	1.00
10_A	154_L	1.235	1.00
19_C	284_I	1.227	1.00
160_V	273_P	1.219	1.00
8_I	31_V	1.217	1.00
69_Q	96_E	1.215	1.00
103_A	106_E	1.210	1.00
141_G	144_I	1.210	1.00
113_R	139_V	1.202	1.00
19_C	23_L	1.201	1.00
277_S	333_D	1.200	1.00
177_E	216_T	1.186	1.00
153_P	156_K	1.182	1.00
236_S	240_D	1.176	1.00
10_A	118_V	1.172	1.00
198_D	202_A	1.170	1.00
241_D	244_D	1.169	1.00
118_V	121_P	1.168	1.00
123_T	280_N	1.163	1.00
240_D	243_L	1.155	1.00
253_L	256_A	1.152	1.00
181_V	185_G	1.151	1.00
12_A	17_A	1.150	1.00
122_I	138_E	1.145	1.00
64_D	67_V	1.145	1.00
96_E	99_Q	1.142	1.00
234_D	238_S	1.140	1.00
312_T	315_R	1.134	1.00
24_A	108_Q	1.129	1.00
171_G	175_E	1.124	1.00
10_A	148_T	1.118	1.00
47_K	299_I	1.108	1.00
129_V	280_N	1.108	1.00
239_I	243_L	1.103	1.00
31_V	111_E	1.100	1.00
33_L	113_R	1.100	1.00
18_Q	60_F	1.096	1.00
39_D	114_F	1.080	1.00
116_A	137_E	1.079	1.00
78_S	82_Y	1.079	1.00
102_V	112_Y	1.076	1.00
33_L	116_A	1.070	1.00
254_A	258_K	1.070	1.00
171_G	174_W	1.070	1.00
253_L	257_T	1.066	1.00
121_P	157_K	1.060	1.00
181_V	184_E	1.059	1.00
284_I	332_Y	1.053	1.00
25_E	104_A	1.045	1.00
10_A	144_I	1.041	1.00
44_Q	47_K	1.040	1.00
150_P	290_T	1.035	1.00
18_Q	22_D	1.027	1.00
65_D	100_W	1.022	1.00
59_A	311_I	1.018	1.00
121_P	158_L	1.016	1.00
9_V	20_A	1.013	1.00
182_D	185_G	1.013	1.00
291_V	301_K	1.012	1.00
277_S	326_A	1.006	1.00
93_E	96_E	0.999	1.00
9_V	30_V	0.999	1.00
65_D	69_Q	0.998	1.00
69_Q	99_Q	0.998	1.00
282_M	332_Y	0.995	1.00
5_H	29_D	0.983	1.00
45_S	48_S	0.982	1.00
291_V	344_A	0.981	1.00
32_V	112_Y	0.980	1.00
24_A	109_G	0.978	1.00
331_I	334_D	0.976	1.00
70_Y	90_A	0.974	1.00
161_T	274_A	0.970	1.00
54_A	63_P	0.968	1.00
62_V	100_W	0.966	1.00
30_V	110_A	0.966	1.00
242_H	246_W	0.961	1.00
62_V	104_A	0.959	1.00
243_L	246_W	0.949	1.00
174_W	219_V	0.948	1.00
66_V	100_W	0.943	1.00
20_A	30_V	0.942	1.00
21_R	60_F	0.940	1.00
251_P	254_A	0.937	1.00
315_R	331_I	0.936	1.00
118_V	153_P	0.932	1.00
208_W	220_G	0.926	1.00
163_L	274_A	0.925	1.00
118_V	157_K	0.925	1.00
12_A	34_E	0.922	1.00
236_S	263_Q	0.920	1.00
5_H	111_E	0.919	1.00
173_E	177_E	0.918	1.00
172_I	175_E	0.916	1.00
17_A	105_G	0.915	1.00
308_A	311_I	0.912	1.00
105_G	109_G	0.911	1.00
330_S	334_D	0.910	1.00
103_A	107_Q	0.908	1.00
28_Y	317_F	0.908	1.00
52_T	304_E	0.908	1.00
273_P	283_A	0.904	1.00
283_A	287_T	0.903	1.00
239_I	242_H	0.901	1.00
146_D	281_F	0.898	1.00
348_L	352_Q	0.892	1.00
52_T	297_E	0.890	1.00
271_Q	290_T	0.884	1.00
14_P	303_M	0.879	1.00
278_T	281_F	0.873	1.00
160_V	278_T	0.870	1.00
341_A	345_R	0.869	1.00
123_T	279_D	0.864	1.00
234_D	237_K	0.862	1.00
57_M	62_V	0.856	1.00
66_V	97_F	0.852	1.00
52_T	55_S	0.852	1.00
34_E	114_F	0.849	1.00
17_A	102_V	0.847	1.00
318_M	323_D	0.846	1.00
248_E	251_P	0.845	1.00
27_G	30_V	0.844	1.00
113_R	137_E	0.840	1.00
158_L	278_T	0.838	1.00
277_S	329_L	0.837	1.00
55_S	58_G	0.835	1.00
69_Q	100_W	0.834	1.00
121_P	281_F	0.828	1.00
54_A	90_A	0.828	1.00
123_T	129_V	0.826	1.00
145_I	309_A	0.825	1.00
232_F	235_A	0.824	1.00
252_R	255_D	0.818	1.00
254_A	257_T	0.813	1.00
106_E	109_G	0.806	1.00
50_A	53_F	0.798	1.00
23_L	310_A	0.797	1.00
276_F	337_H	0.797	1.00
23_L	28_Y	0.794	1.00
31_V	141_G	0.793	1.00
17_A	98_K	0.792	1.00
33_L	141_G	0.791	1.00
319_G	325_S	0.790	1.00
100_W	104_A	0.788	1.00
154_L	281_F	0.788	1.00
106_E	111_E	0.786	1.00
331_I	335_L	0.785	1.00
24_A	105_G	0.780	1.00
22_D	26_R	0.778	1.00
250_D	254_A	0.774	1.00
310_A	314_D	0.773	1.00
295_W	347_R	0.773	1.00
24_A	111_E	0.773	1.00
255_D	259_L	0.772	1.00
33_L	131_V	0.772	1.00
116_A	134_D	0.771	1.00
48_S	89_G	0.771	1.00
49_T	53_F	0.767	1.00
121_P	154_L	0.767	1.00
96_E	213_G	0.762	1.00
127_E	130_G	0.762	1.00
6_D	141_G	0.762	1.00
316_C	319_G	0.756	1.00
6_D	139_V	0.755	1.00
177_E	215_D	0.754	1.00
38_E	114_F	0.754	1.00
251_P	255_D	0.753	1.00
58_G	67_V	0.749	1.00
316_C	331_I	0.748	1.00
268_A	292_D	0.746	1.00
24_A	30_V	0.744	1.00
244_D	247_M	0.744	1.00
42_P	45_S	0.743	1.00
319_G	323_D	0.743	1.00
24_A	106_E	0.738	1.00
243_L	247_M	0.736	1.00
22_D	25_E	0.733	1.00
326_A	330_S	0.732	1.00
276_F	288_V	0.725	1.00
242_H	245_Y	0.725	1.00
131_V	141_G	0.724	1.00
57_M	303_M	0.723	1.00
146_D	158_L	0.722	1.00
299_I	303_M	0.722	1.00
93_E	213_G	0.721	1.00
193_M	196_R	0.721	1.00
52_T	339_R	0.721	1.00
289_P	336_W	0.718	1.00
224_I	227_E	0.717	1.00
94_F	98_K	0.717	1.00
100_W	103_A	0.717	1.00
98_K	102_V	0.716	1.00
152_A	155_A	0.716	1.00
231_R	235_A	0.712	1.00
236_S	239_I	0.712	1.00
23_L	313_A	0.711	1.00
75_V	83_F	0.710	1.00
283_A	288_V	0.710	1.00
218_K	222_C	0.707	1.00
26_R	310_A	0.707	1.00
291_V	295_W	0.706	1.00
195_L	198_D	0.701	1.00
335_L	338_K	0.699	1.00
143_I	282_M	0.698	1.00
20_A	110_A	0.697	1.00
194_M	197_L	0.697	1.00
304_E	336_W	0.693	1.00
235_A	239_I	0.692	1.00
146_D	152_A	0.689	1.00
131_V	144_I	0.685	1.00
134_D	137_E	0.685	1.00
75_V	78_S	0.684	1.00
301_K	343_N	0.684	1.00
58_G	64_D	0.682	1.00
146_D	153_P	0.677	1.00
43_R	47_K	0.674	1.00
168_Q	172_I	0.674	1.00
299_I	302_C	0.671	1.00
167_N	348_L	0.671	1.00
63_P	66_V	0.667	1.00
324_T	328_A	0.667	1.00
29_D	142_D	0.666	1.00
176_M	219_V	0.666	1.00
50_A	300_H	0.665	1.00
92_L	97_F	0.664	1.00
22_D	56_M	0.661	1.00
144_I	281_F	0.660	1.00
17_A	32_V	0.659	1.00
169_A	173_E	0.658	1.00
227_E	230_Q	0.656	1.00
297_E	301_K	0.655	1.00
272_L	337_H	0.654	1.00
238_S	247_M	0.652	1.00
239_I	246_W	0.651	1.00
297_E	300_H	0.650	1.00
230_Q	233_G	0.650	1.00
19_C	313_A	0.649	1.00
20_A	105_G	0.649	1.00
338_K	342_P	0.648	1.00
170_I	174_W	0.646	1.00
30_V	105_G	0.646	1.00
8_I	129_V	0.645	1.00
340_V	344_A	0.645	1.00
325_S	328_A	0.645	1.00
18_Q	101_L	0.640	1.00
290_T	305_S	0.640	1.00
154_L	157_K	0.637	1.00
307_R	311_I	0.634	1.00
54_A	58_G	0.632	1.00
327_D	331_I	0.629	1.00
56_M	60_F	0.627	1.00
73_D	192_A	0.626	1.00
291_V	347_R	0.625	1.00
190_S	193_M	0.623	1.00
272_L	341_A	0.622	1.00
47_K	94_F	0.621	1.00
316_C	328_A	0.620	1.00
69_Q	92_L	0.619	1.00
117_R	153_P	0.619	1.00
235_A	240_D	0.619	1.00
334_D	338_K	0.619	1.00
294_L	351_T	0.618	1.00
301_K	340_V	0.617	1.00
263_Q	266_G	0.615	1.00
155_A	283_A	0.615	1.00
330_S	333_D	0.611	1.00
284_I	306_A	0.609	1.00
272_L	276_F	0.608	1.00
194_M	198_D	0.608	1.00
233_G	237_K	0.605	1.00
230_Q	242_H	0.605	1.00
105_G	112_Y	0.604	1.00
168_Q	171_G	0.604	1.00
279_D	326_A	0.603	1.00
19_C	310_A	0.603	1.00
129_V	132_K	0.600	1.00
77_E	80_H	0.595	1.00
67_V	70_Y	0.593	1.00
22_D	307_R	0.592	1.00
93_E	216_T	0.592	1.00
5_H	139_V	0.592	1.00
77_E	81_E	0.592	1.00
193_M	198_D	0.586	1.00
173_E	218_K	0.586	1.00
193_M	197_L	0.586	1.00
282_M	329_L	0.584	1.00
17_A	112_Y	0.583	1.00
123_T	127_E	0.582	1.00
21_R	24_A	0.581	1.00
142_D	317_F	0.580	1.00
170_I	225_Q	0.580	1.00
143_I	317_F	0.579	1.00
316_C	327_D	0.579	1.00
106_E	110_A	0.577	1.00
314_D	318_M	0.575	1.00
77_E	83_F	0.573	1.00
207_S	221_I	0.573	1.00
28_Y	313_A	0.572	1.00
233_G	238_S	0.570	1.00
319_G	324_T	0.568	1.00
122_I	125_G	0.566	1.00
286_D	296_G	0.566	1.00
208_W	212_T	0.565	1.00
7_V	143_I	0.564	1.00
7_V	19_C	0.564	1.00
234_D	242_H	0.562	1.00
144_I	280_N	0.562	1.00
129_V	144_I	0.561	1.00
239_I	263_Q	0.561	1.00
286_D	302_C	0.560	1.00
324_T	327_D	0.560	1.00
115_E	135_G	0.558	1.00
162_D	271_Q	0.557	1.00
56_M	59_A	0.556	1.00
126_G	280_N	0.555	1.00
21_R	110_A	0.555	1.00
75_V	82_Y	0.555	1.00
345_R	349_T	0.554	1.00
166_S	170_I	0.554	1.00
282_M	333_D	0.553	1.00
143_I	313_A	0.552	1.00
219_V	222_C	0.552	1.00
311_I	315_R	0.551	1.00
295_W	350_M	0.551	1.00
230_Q	234_D	0.550	1.00
53_F	56_M	0.550	1.00
151_A	156_K	0.549	1.00
166_S	269_H	0.548	1.00
327_D	330_S	0.548	1.00
167_N	172_I	0.548	1.00
105_G	108_Q	0.545	1.00
144_I	154_L	0.544	1.00
206_Y	210_F	0.542	1.00
12_A	39_D	0.541	1.00
304_E	308_A	0.541	1.00
38_E	41_F	0.540	1.00
191_D	194_M	0.540	1.00
48_S	91_V	0.539	1.00
245_Y	248_E	0.539	1.00
30_V	109_G	0.539	1.00
350_M	353_L	0.536	1.00
240_D	258_K	0.535	1.00
143_I	316_C	0.534	1.00
238_S	242_H	0.531	1.00
266_G	271_Q	0.529	1.00
148_T	154_L	0.528	1.00
218_K	221_I	0.528	1.00
247_M	251_P	0.524	1.00
289_P	297_E	0.524	1.00
78_S	81_E	0.524	1.00
174_W	177_E	0.523	1.00
172_I	176_M	0.523	1.00
169_A	176_M	0.523	1.00
251_P	257_T	0.521	1.00
165_R	168_Q	0.521	1.00
217_A	220_G	0.521	1.00
219_V	223_Y	0.520	1.00
233_G	242_H	0.518	1.00
75_V	84_V	0.517	1.00
284_I	302_C	0.516	1.00
148_T	283_A	0.516	1.00
57_M	66_V	0.516	1.00
238_S	243_L	0.516	1.00
19_C	22_D	0.515	1.00
142_D	280_N	0.515	1.00
210_F	220_G	0.515	1.00
308_A	332_Y	0.514	1.00
10_A	121_P	0.513	1.00
74_V	77_E	0.512	1.00
234_D	239_I	0.511	1.00
143_I	325_S	0.510	1.00
115_E	134_D	0.510	1.00
232_F	236_S	0.509	1.00
170_I	265_R	0.508	1.00
302_C	306_A	0.508	1.00
325_S	329_L	0.507	1.00
235_A	243_L	0.507	1.00
250_D	253_L	0.506	1.00
30_V	111_E	0.505	1.00
253_L	258_K	0.502	1.00
15_A	145_I	0.502	1.00
205_G	245_Y	0.502	1.00
236_S	243_L	0.502	1.00
26_R	311_I	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1pn0A	3	0.939	100	0.369	Contact Map
2qa1A	2	0.9049	100	0.375	Contact Map
4k22A	4	0.8244	100	0.376	Contact Map
2qa2A	2	0.9122	100	0.379	Contact Map
4bjzA	2	0.9122	100	0.38	Contact Map
2dkhA	2	0.9073	100	0.384	Contact Map
4n9xA	5	0.8634	100	0.387	Contact Map
4k5sA	2	0.9049	100	0.39	Contact Map
3ihgA	3	0.9439	100	0.391	Contact Map
3c96A	1	0.8439	100	0.392	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0111 seconds.