GREMLIN Database
Q9HRZ1 - Methylmalonyl-CoA mutase, subunit alpha
UniProt: Q9HRZ1 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 653 (541)
Sequences: 2274 (879)
Seq/√Len: 37.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
360_V405_M4.6791.00
369_D372_E3.9691.00
238_T593_V3.8881.00
513_E516_A3.7991.00
610_R642_D3.6761.00
276_D628_K3.6301.00
364_L370_V3.4491.00
220_S235_A3.2801.00
220_S237_D3.2691.00
243_E277_Q3.2161.00
550_E556_R3.2091.00
403_T515_Q3.0461.00
333_I377_L3.0461.00
486_H564_F3.0071.00
344_T543_V2.9671.00
191_T195_F2.9501.00
436_D462_K2.9331.00
138_D145_D2.8821.00
255_S286_R2.8751.00
361_Q522_D2.8331.00
388_L502_Y2.8001.00
281_D284_E2.7921.00
598_D601_A2.7541.00
592_D596_D2.7321.00
399_R508_D2.6721.00
439_I476_T2.6611.00
613_A640_L2.5851.00
599_S603_E2.5791.00
387_I391_V2.5541.00
399_R511_E2.5491.00
509_D513_E2.5461.00
388_L503_V2.5371.00
252_D284_E2.5281.00
273_A628_K2.4621.00
371_D416_S2.4611.00
189_A585_R2.4211.00
270_M627_V2.4051.00
369_D412_Q2.4041.00
412_Q416_S2.3431.00
527_M536_V2.3211.00
381_F397_A2.3151.00
505_G509_D2.3031.00
319_E366_A2.2740.99
542_D546_D2.2670.99
546_D550_E2.2500.99
406_E417_K2.2450.99
361_Q365_D2.2440.99
222_A638_N2.2360.99
361_Q409_F2.2250.99
588_E592_D2.2170.99
164_T399_R2.2140.99
515_Q519_D2.1960.99
444_Y484_L2.1940.99
584_R588_E2.1810.99
374_A416_S2.1790.99
508_D512_A2.1150.99
520_E539_Q2.1130.99
439_I462_K2.0750.99
547_R556_R2.0580.99
640_L644_F2.0570.99
436_D472_E2.0420.99
437_N483_I2.0400.99
371_D412_Q2.0340.99
386_N492_D2.0300.99
321_C330_T1.9980.99
612_A622_Y1.9980.99
423_T454_T1.9820.99
277_Q630_Y1.9740.99
305_F637_C1.9720.99
349_I510_I1.9490.98
347_Q539_Q1.9340.98
252_D280_V1.9300.98
446_A484_L1.9200.98
243_E630_Y1.9110.98
600_E604_A1.9020.98
405_M411_A1.9000.98
603_E607_A1.8940.98
319_E323_A1.8780.98
587_I591_N1.8770.98
154_D508_D1.8620.98
161_E402_A1.8570.98
611_A614_A1.8560.98
627_V636_I1.8540.98
621_P625_A1.8540.98
566_V569_E1.8440.98
602_V631_A1.8300.98
351_F535_W1.8290.98
239_L630_Y1.8230.97
107_E111_E1.8040.97
282_R324_E1.8040.97
133_G389_E1.8010.97
110_E115_G1.7870.97
349_I514_A1.7690.97
355_D527_M1.7590.97
240_A243_E1.7380.97
357_I404_I1.7210.96
353_L356_G1.7210.96
196_N248_G1.7180.96
529_R532_E1.7080.96
444_Y448_A1.7000.96
608_D625_A1.6930.96
308_E532_E1.6720.96
381_F394_F1.6680.96
161_E407_E1.6600.96
440_V443_A1.6480.95
385_N445_Q1.6370.95
605_A629_A1.6140.95
557_V563_E1.6130.95
137_V502_Y1.5980.95
357_I409_F1.5890.94
514_A518_L1.5800.94
197_Y471_E1.5720.94
138_D141_Y1.5680.94
554_K563_E1.5650.94
271_Y275_G1.5610.94
519_D523_S1.5600.94
612_A615_G1.5580.94
374_A405_M1.5550.94
442_V445_Q1.5390.93
358_E362_T1.5390.93
443_A488_S1.5310.93
335_G352_T1.5280.93
370_V411_A1.5090.93
470_T473_S1.5090.93
348_E393_K1.5090.93
400_M514_A1.5010.92
120_R123_E1.5000.92
641_R646_E1.4960.92
276_D282_R1.4670.92
461_G474_V1.4610.91
429_T445_Q1.4550.91
357_I518_L1.4480.91
402_A406_E1.4470.91
318_F363_A1.4400.91
529_R533_D1.4370.91
594_K602_V1.4320.91
106_R144_D1.4310.91
475_R566_V1.4290.91
601_A625_A1.4240.90
238_T632_S1.4200.90
638_N642_D1.4150.90
270_M633_V1.4150.90
282_R320_F1.4120.90
240_A596_D1.4090.90
371_D413_N1.3970.89
179_M478_L1.3970.89
240_A630_Y1.3800.89
637_C641_R1.3720.89
609_L622_Y1.3600.88
607_A611_A1.3450.88
517_I535_W1.3430.88
128_F136_S1.3200.87
400_M515_Q1.3190.87
272_I282_R1.3170.86
451_L497_L1.3150.86
385_N429_T1.2990.86
239_L243_E1.2990.86
346_A513_E1.2980.86
609_L626_A1.2850.85
312_R644_F1.2830.85
265_S623_I1.2810.85
446_A457_L1.2770.85
612_A617_E1.2750.85
493_T498_A1.2750.85
265_S640_L1.2740.85
179_M482_Q1.2730.85
387_I447_L1.2700.84
318_F366_A1.2660.84
135_Q513_E1.2570.84
250_P253_E1.2540.84
107_E110_E1.2530.84
601_A605_A1.2510.83
383_A390_E1.2500.83
535_W539_Q1.2500.83
143_P151_Y1.2490.83
141_Y505_G1.2490.83
344_T347_Q1.2440.83
605_A608_D1.2330.83
497_L503_V1.2310.82
146_V149_R1.2310.82
182_Y300_R1.2250.82
362_T365_D1.2240.82
121_F126_E1.2180.82
346_A510_I1.2110.81
381_F423_T1.2070.81
289_I330_T1.2070.81
623_I627_V1.2040.81
422_H456_S1.2020.81
215_Q300_R1.2010.81
591_N594_K1.1940.80
178_T205_G1.1920.80
195_F206_L1.1900.80
315_T362_T1.1870.80
386_N556_R1.1850.80
347_Q517_I1.1800.80
196_N200_D1.1750.79
475_R479_R1.1730.79
150_D154_D1.1710.79
638_N641_R1.1710.79
272_I624_V1.1700.79
450_V490_A1.1700.79
142_T145_D1.1680.79
626_A631_A1.1650.79
516_A519_D1.1630.79
323_A372_E1.1600.79
524_R535_W1.1580.78
608_D612_A1.1520.78
132_T550_E1.1460.78
140_L494_I1.1400.77
550_E555_E1.1370.77
623_I636_I1.1330.77
411_A416_S1.1310.77
591_N595_G1.1300.77
106_R110_E1.1270.76
189_A244_T1.1260.76
105_G108_D1.1250.76
120_R124_R1.1160.76
141_Y502_Y1.1150.76
182_Y215_Q1.1090.75
414_P417_K1.1080.75
584_R591_N1.1020.75
450_V457_L1.0960.74
594_K632_S1.0940.74
593_V630_Y1.0940.74
517_I521_V1.0930.74
610_R614_A1.0890.74
180_R205_G1.0880.74
352_T381_F1.0880.74
131_D137_V1.0870.74
195_F208_M1.0860.74
208_M246_F1.0830.74
358_E361_Q1.0750.73
266_V637_C1.0750.73
462_K472_E1.0750.73
517_I539_Q1.0740.73
609_L640_L1.0730.73
399_R402_A1.0630.72
270_M636_I1.0610.72
131_D135_Q1.0600.72
118_L122_G1.0580.72
240_A593_V1.0490.71
256_T271_Y1.0390.70
156_G164_T1.0370.70
530_A536_V1.0370.70
318_F331_I1.0340.70
208_M245_V1.0310.70
371_D374_A1.0310.70
157_F160_E1.0240.69
581_D585_R1.0220.69
164_T511_E1.0180.69
447_L490_A1.0170.69
303_Y649_P1.0150.69
402_A417_K1.0140.68
358_E528_R1.0130.68
429_T442_V1.0090.68
607_A610_R1.0060.68
590_L632_S1.0050.68
139_R170_T1.0040.68
524_R530_A1.0030.68
400_M404_I0.9990.67
161_E406_E0.9960.67
350_A517_I0.9930.67
600_E603_E0.9910.67
610_R643_V0.9890.67
286_R327_K0.9880.66
538_R542_D0.9880.66
639_T643_V0.9870.66
282_R624_V0.9850.66
447_L451_L0.9850.66
353_L404_I0.9820.66
375_P416_S0.9820.66
520_E535_W0.9800.66
190_E193_E0.9790.66
391_V451_L0.9760.65
444_Y488_S0.9760.65
339_R426_A0.9730.65
424_Q460_N0.9710.65
294_L359_Y0.9710.65
387_I484_L0.9690.65
269_A620_M0.9660.65
601_A604_A0.9640.64
212_L215_Q0.9620.64
244_T247_D0.9590.64
517_I520_E0.9570.64
371_D411_A0.9570.64
404_I515_Q0.9560.64
428_S551_I0.9540.64
381_F421_F0.9510.63
272_I325_T0.9510.63
343_A540_I0.9510.63
601_A629_A0.9500.63
451_L490_A0.9490.63
232_S301_N0.9490.63
215_Q301_N0.9450.63
554_K557_V0.9450.63
117_T120_R0.9400.63
518_L522_D0.9390.62
263_P637_C0.9370.62
448_A451_L0.9350.62
356_G401_W0.9340.62
467_S575_I0.9310.62
614_A643_V0.9280.62
383_A394_F0.9250.61
599_S602_V0.9250.61
182_Y209_A0.9250.61
346_A350_A0.9210.61
129_E137_V0.9130.60
135_Q509_D0.9130.60
597_R601_A0.9120.60
329_N376_Q0.9040.59
516_A558_I0.9030.59
301_N649_P0.9020.59
527_M649_P0.9010.59
608_D622_Y0.9000.59
168_Y494_I0.9000.59
490_A594_K0.8990.59
407_E410_D0.8980.59
585_R588_E0.8950.59
140_L157_F0.8930.59
338_I355_D0.8920.58
308_E529_R0.8910.58
215_Q232_S0.8900.58
450_V484_L0.8890.58
467_S470_T0.8870.58
388_L500_S0.8840.58
318_F330_T0.8810.57
370_V409_F0.8770.57
610_R639_T0.8710.57
383_A423_T0.8690.56
537_Q541_Q0.8670.56
512_A516_A0.8650.56
434_Q479_R0.8640.56
442_V460_N0.8640.56
371_D375_P0.8630.56
275_G285_L0.8620.56
520_E524_R0.8610.56
127_S139_R0.8580.55
163_Y412_Q0.8570.55
244_T589_H0.8550.55
505_G508_D0.8540.55
388_L497_L0.8500.55
436_D476_T0.8490.55
422_H458_H0.8490.55
320_F325_T0.8480.55
212_L300_R0.8470.54
509_D512_A0.8450.54
274_V278_Q0.8450.54
135_Q388_L0.8450.54
343_A382_N0.8390.54
587_I594_K0.8380.54
565_E569_E0.8380.54
239_L593_V0.8370.54
144_D147_A0.8350.53
411_A417_K0.8340.53
382_N428_S0.8340.53
604_A608_D0.8310.53
137_V493_T0.8300.53
583_E587_I0.8270.53
360_V370_V0.8270.53
443_A453_G0.8260.53
161_E403_T0.8260.53
530_A535_W0.8260.53
232_S302_T0.8250.53
384_H426_A0.8240.52
272_I320_F0.8230.52
156_G399_R0.8220.52
189_A193_E0.8220.52
479_R482_Q0.8210.52
180_R257_S0.8170.52
192_N248_G0.8170.52
403_T511_E0.8150.52
448_A498_A0.8140.52
165_R498_A0.8140.52
475_R569_E0.8130.51
263_P266_V0.8100.51
595_G614_A0.8070.51
246_F249_I0.8070.51
388_L506_L0.8060.51
238_T594_K0.8050.51
157_F494_I0.8050.51
493_T502_Y0.8010.50
294_L528_R0.8010.50
141_Y145_D0.8000.50
565_E568_D0.7980.50
130_T136_S0.7970.50
132_T556_R0.7960.50
212_L303_Y0.7950.50
333_I360_V0.7930.50
601_A611_A0.7880.49
196_N247_D0.7880.49
454_T457_L0.7870.49
193_E197_Y0.7870.49
330_T333_I0.7860.49
314_I318_F0.7850.49
314_I317_I0.7850.49
151_Y155_I0.7840.49
318_F376_Q0.7830.49
293_I305_F0.7800.49
222_A634_G0.7800.49
551_I558_I0.7780.48
539_Q542_D0.7770.48
288_T378_S0.7740.48
436_D440_V0.7730.48
335_G381_F0.7730.48
316_D319_E0.7720.48
484_L569_E0.7710.48
182_Y302_T0.7710.48
182_Y212_L0.7710.48
391_V503_V0.7710.48
338_I540_I0.7700.48
283_E324_E0.7700.48
497_L502_Y0.7690.48
163_Y570_E0.7690.48
323_A614_A0.7680.47
345_A384_H0.7680.47
357_I410_D0.7680.47
314_I331_I0.7670.47
590_L594_K0.7670.47
146_V501_Y0.7670.47
215_Q302_T0.7670.47
197_Y200_D0.7640.47
239_L277_Q0.7640.47
357_I411_A0.7630.47
133_G345_A0.7560.46
380_F424_Q0.7560.46
251_L256_T0.7550.46
158_P387_I0.7540.46
240_A592_D0.7540.46
198_L474_V0.7540.46
318_F373_F0.7530.46
251_L278_Q0.7490.46
252_D281_D0.7470.46
333_I373_F0.7450.45
339_R345_A0.7450.45
334_S352_T0.7450.45
510_I514_A0.7440.45
141_Y388_L0.7440.45
204_T253_E0.7440.45
336_Y340_E0.7400.45
533_D536_V0.7370.45
590_L593_V0.7360.45
189_A589_H0.7360.45
295_K337_H0.7360.45
298_I301_N0.7350.45
347_Q543_V0.7290.44
611_A617_E0.7280.44
161_E417_K0.7260.44
505_G512_A0.7250.44
191_T245_V0.7240.44
404_I647_H0.7230.43
147_A154_D0.7190.43
358_E527_M0.7190.43
622_Y626_A0.7160.43
625_A629_A0.7140.43
370_V405_M0.7130.43
357_I361_Q0.7130.43
124_R491_A0.7130.43
149_R155_I0.7120.43
382_N393_K0.7120.43
189_A223_T0.7110.42
257_S288_T0.7100.42
230_G233_G0.7090.42
334_S460_N0.7090.42
239_L270_M0.7060.42
179_M402_A0.7060.42
397_A419_L0.7050.42
372_E416_S0.7050.42
502_Y506_L0.7040.42
340_E427_G0.7030.42
434_Q569_E0.7000.41
574_D578_V0.7000.41
360_V373_F0.6970.41
242_M274_V0.6970.41
159_G165_R0.6960.41
424_Q458_H0.6960.41
520_E523_S0.6950.41
186_G191_T0.6930.41
269_A624_V0.6910.41
538_R558_I0.6900.41
625_A628_K0.6900.41
163_Y414_P0.6880.40
233_G336_Y0.6870.40
461_G640_L0.6860.40
192_N196_N0.6820.40
295_K300_R0.6810.40
434_Q475_R0.6800.40
605_A610_R0.6790.40
280_V284_E0.6780.40
612_A644_F0.6770.40
352_T459_T0.6770.40
315_T366_A0.6760.39
352_T540_I0.6740.39
121_F124_R0.6730.39
581_D584_R0.6730.39
193_E200_D0.6710.39
189_A624_V0.6710.39
142_T157_F0.6710.39
357_I522_D0.6690.39
566_V570_E0.6680.39
407_E411_A0.6680.39
318_F528_R0.6680.39
608_D617_E0.6660.39
533_D538_R0.6640.38
294_L527_M0.6640.38
305_F640_L0.6620.38
287_G328_F0.6600.38
515_Q518_L0.6580.38
364_L409_F0.6580.38
313_V317_I0.6570.38
169_P358_E0.6560.38
620_M623_I0.6560.38
312_R316_D0.6550.38
135_Q389_E0.6540.38
271_Y281_D0.6520.37
119_D122_G0.6500.37
593_V607_A0.6490.37
198_L478_L0.6490.37
462_K492_D0.6490.37
117_T121_F0.6490.37
489_G492_D0.6490.37
634_G638_N0.6480.37
214_T267_L0.6450.37
113_T139_R0.6450.37
236_I242_M0.6440.37
413_N639_T0.6420.37
628_K631_A0.6420.37
444_Y447_L0.6400.36
351_F533_D0.6400.36
259_T337_H0.6390.36
151_Y157_F0.6390.36
329_N420_K0.6380.36
450_V559_V0.6380.36
406_E410_D0.6370.36
133_G434_Q0.6370.36
363_A366_A0.6370.36
272_I558_I0.6360.36
210_F424_Q0.6360.36
332_S380_F0.6350.36
412_Q648_Q0.6350.36
593_V596_D0.6340.36
585_R638_N0.6330.36
351_F498_A0.6320.36
516_A520_E0.6320.36
351_F517_I0.6320.36
591_N642_D0.6310.36
266_V636_I0.6310.36
108_D112_E0.6290.35
336_Y427_G0.6290.35
158_P164_T0.6270.35
132_T386_N0.6260.35
425_T457_L0.6240.35
435_I490_A0.6230.35
435_I466_L0.6230.35
138_D505_G0.6220.35
187_T190_E0.6210.35
511_E515_Q0.6200.35
128_F555_E0.6190.35
444_Y490_A0.6180.35
268_L289_I0.6180.35
177_W393_K0.6170.35
176_L179_M0.6160.34
610_R647_H0.6160.34
477_A540_I0.6150.34
427_G464_E0.6150.34
353_L400_M0.6140.34
394_F423_T0.6140.34
193_E471_E0.6140.34
399_R403_T0.6120.34
346_A443_A0.6120.34
447_L555_E0.6120.34
348_E390_E0.6120.34
142_T648_Q0.6120.34
453_G496_P0.6120.34
364_L369_D0.6110.34
209_A337_H0.6110.34
460_N464_E0.6110.34
115_G119_D0.6110.34
240_A647_H0.6110.34
289_I318_F0.6110.34
388_L536_V0.6100.34
118_L123_E0.6100.34
223_T592_D0.6100.34
412_Q567_D0.6100.34
104_D108_D0.6070.34
383_A421_F0.6060.34
547_R551_I0.6060.34
199_L250_P0.6050.34
109_W139_R0.6050.34
218_Y224_M0.6050.34
512_A642_D0.6050.34
353_L518_L0.6040.33
605_A626_A0.6040.33
370_V416_S0.6020.33
443_A556_R0.6020.33
334_S380_F0.6020.33
293_I304_I0.6010.33
183_A191_T0.6000.33
118_L124_R0.5990.33
356_G456_S0.5980.33
346_A453_G0.5970.33
504_E507_T0.5960.33
549_Q553_E0.5960.33
259_T295_K0.5950.33
413_N416_S0.5940.33
557_V562_N0.5930.33
269_A273_A0.5930.33
368_L644_F0.5930.33
283_E327_K0.5920.33
198_L203_Q0.5910.32
138_D147_A0.5900.32
595_G607_A0.5880.32
188_A310_S0.5860.32
139_R569_E0.5860.32
303_Y307_P0.5860.32
450_V485_A0.5860.32
212_L302_T0.5850.32
269_A320_F0.5840.32
613_A619_V0.5840.32
180_R287_G0.5830.32
209_A259_T0.5820.32
307_P310_S0.5820.32
412_Q642_D0.5810.32
204_T254_V0.5800.32
216_M646_E0.5800.32
434_Q476_T0.5800.32
203_Q206_L0.5800.32
265_S498_A0.5800.32
298_I355_D0.5800.32
263_P305_F0.5790.32
345_A389_E0.5790.32
365_D553_E0.5790.32
202_G495_D0.5780.31
403_T406_E0.5770.31
620_M624_V0.5770.31
104_D107_E0.5770.31
167_V418_Q0.5770.31
146_V614_A0.5760.31
243_E270_M0.5760.31
206_L210_F0.5750.31
240_A277_Q0.5750.31
598_D624_V0.5750.31
443_A483_I0.5740.31
386_N547_R0.5740.31
509_D516_A0.5730.31
404_I417_K0.5720.31
385_N483_I0.5710.31
234_V245_V0.5700.31
116_P120_R0.5700.31
345_A510_I0.5690.31
222_A226_Q0.5680.31
484_L488_S0.5680.31
389_E434_Q0.5680.31
119_D127_S0.5680.31
276_D280_V0.5670.31
451_L503_V0.5650.30
323_A601_A0.5650.30
301_N537_Q0.5640.30
134_G149_R0.5640.30
544_A548_Q0.5640.30
183_A195_F0.5630.30
180_R340_E0.5630.30
297_Y368_L0.5620.30
206_L259_T0.5610.30
462_K573_A0.5600.30
622_Y625_A0.5600.30
400_M518_L0.5600.30
569_E648_Q0.5600.30
570_E588_E0.5590.30
319_E322_A0.5590.30
346_A349_I0.5560.30
584_R592_D0.5560.30
235_A241_D0.5560.30
605_A615_G0.5550.30
189_A247_D0.5550.30
192_N393_K0.5550.30
364_L411_A0.5550.30
466_L573_A0.5550.30
548_Q589_H0.5550.30
476_T644_F0.5540.30
260_I264_A0.5540.30
567_D601_A0.5540.30
619_V640_L0.5530.30
199_L252_D0.5530.30
617_E621_P0.5530.30
593_V599_S0.5510.29
195_F246_F0.5510.29
513_E556_R0.5510.29
347_Q428_S0.5500.29
401_W514_A0.5490.29
486_H556_R0.5490.29
518_L633_V0.5480.29
588_E638_N0.5480.29
301_N429_T0.5470.29
208_M236_I0.5460.29
111_E115_G0.5460.29
296_E300_R0.5450.29
182_Y232_S0.5440.29
216_M232_S0.5440.29
207_S481_Q0.5430.29
207_S424_Q0.5430.29
573_A577_E0.5410.29
428_S586_Q0.5410.29
167_V498_A0.5390.29
334_S459_T0.5390.29
360_V364_L0.5390.29
261_N295_K0.5390.29
120_R127_S0.5390.29
543_V547_R0.5380.28
238_T241_D0.5380.28
203_Q446_A0.5370.28
194_R198_L0.5370.28
350_A539_Q0.5370.28
369_D503_V0.5370.28
193_E631_A0.5370.28
237_D586_Q0.5360.28
276_D281_D0.5360.28
447_L556_R0.5360.28
595_G604_A0.5360.28
203_Q498_A0.5340.28
410_D414_P0.5340.28
301_N536_V0.5340.28
459_T481_Q0.5330.28
282_R325_T0.5330.28
509_D617_E0.5320.28
588_E595_G0.5320.28
250_P280_V0.5320.28
115_G120_R0.5320.28
533_D570_E0.5320.28
386_N542_D0.5310.28
374_A419_L0.5310.28
212_L304_I0.5310.28
434_Q566_V0.5300.28
169_P199_L0.5300.28
339_R384_H0.5290.28
476_T649_P0.5280.28
448_A483_I0.5280.28
305_F510_I0.5280.28
189_A243_E0.5270.28
451_L502_Y0.5270.28
141_Y493_T0.5270.28
106_R138_D0.5260.28
218_Y317_I0.5260.28
188_A235_A0.5260.28
357_I527_M0.5260.28
483_I557_V0.5260.28
193_E558_I0.5260.28
182_Y301_N0.5250.28
133_G479_R0.5250.28
385_N488_S0.5250.28
469_P483_I0.5250.28
245_V334_S0.5240.27
472_E484_L0.5240.27
415_K418_Q0.5240.27
186_G298_I0.5230.27
137_V147_A0.5230.27
512_A523_S0.5220.27
194_R197_Y0.5210.27
168_Y553_E0.5200.27
159_G166_G0.5190.27
461_G535_W0.5180.27
360_V401_W0.5180.27
130_T512_A0.5180.27
239_L274_V0.5180.27
181_Q203_Q0.5170.27
351_F527_M0.5170.27
126_E512_A0.5170.27
516_A523_S0.5170.27
112_E168_Y0.5160.27
333_I376_Q0.5160.27
204_T503_V0.5160.27
105_G152_D0.5160.27
587_I593_V0.5150.27
357_I400_M0.5140.27
345_A447_L0.5140.27
421_F454_T0.5130.27
118_L643_V0.5130.27
475_R647_H0.5120.27
283_E403_T0.5120.27
179_M485_A0.5120.27
220_S229_V0.5120.27
159_G163_Y0.5110.27
290_Q337_H0.5110.27
360_V505_G0.5100.26
205_G288_T0.5100.26
118_L126_E0.5090.26
210_F335_G0.5090.26
380_F421_F0.5080.26
129_E492_D0.5080.26
197_Y201_E0.5080.26
485_A491_A0.5070.26
180_R424_Q0.5070.26
147_A331_I0.5070.26
372_E412_Q0.5060.26
191_T260_I0.5060.26
314_I366_A0.5060.26
516_A604_A0.5060.26
163_Y418_Q0.5040.26
226_Q587_I0.5040.26
356_G592_D0.5040.26
119_D126_E0.5030.26
126_E157_F0.5020.26
151_Y498_A0.5020.26
424_Q457_L0.5020.26
111_E163_Y0.5020.26
131_D492_D0.5010.26
212_L232_S0.5010.26
163_Y369_D0.5010.26
169_P589_H0.5000.26
108_D111_E0.5000.26
158_P633_V0.5000.26
335_G338_I0.5000.26
127_S134_G0.5000.26
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4xc8A 2 0.9387 100 0.185 Contact Map
4r3uA 2 0.8499 100 0.193 Contact Map
2xijA 2 0.8346 100 0.204 Contact Map
1reqA 1 0.8515 100 0.215 Contact Map
1reqB 1 0.7948 100 0.335 Contact Map
3kp1A 2 0.7626 100 0.564 Contact Map
1ccwB 2 0.6968 100 0.824 Contact Map
3fm3A 1 0.1378 36.4 0.985 Contact Map
3ijdA 2 0.3599 29 0.986 Contact Map
1p8aA 1 0.2037 21.6 0.987 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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