DNAK - HALSA - GREMLIN Contacts

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DNAK - Chaperone protein DnaK

UniProt:	Q9HRY2	Sequences: MASEKILGVDLGTTNSAFAVMEGSDPEIITNEEGDRTTPSIVAHDDGELLVGKPAKNQAVQNPDQTIASIKRHMGEEDYTVALGDDEYTPEEISARILQKIKRDAEEYLGQDVEKAVITVPAYFNDRQRQATKDAGEIAGFDVERIVNEPTAASMAYGLDEDRDQTVLVYDLGGGTFDVSILDLGGGVYEVAATNGDNDLGGDDWDHAIIDHLADNFENEHGIDLREDRQALQRLTEAAEEAKIELSSRKETTVNLPFVTATDSGPVHLEQDITRATFESITEDLIERTVGPTEQALEDAGLSKSDIDDVILVGGSTRMPQVQAQVEDLVGQEPKKNVNPDEAVALGAAVQGGVLSGEVDDIVLVDVTPLSLGIEVKGGLFERLIEKNTAIPTTASKVFTTAADNQTSVQIRVFQGEREIASENELLGDFHLTGIPPAPAGTPQIEVTFEIDADGIVNVEAEDQGSGNAESITIEGGAGLSDEQIDEMQEDAEAHAEEDEQRRRRIEARNEAETAIQRAESLLEENEELVDEDLEADVNDAIDDVQAVLDEDEPEIDALETATEELSDTLQEIGKQAYQQQQDAQAGAAGGAGGMGGMGGMADGPGGAADADGDDEEYVDADFEDVDEE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	629 (571)
Sequences:	6168 (2881)
Seq/√Len:	120.6

ECOLI - DNAK HSCA HSCC
BACSU - DNAK
HALSA - DNAK

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
115_K	142_D	5.317	1.00
197_D	288_R	5.005	1.00
208_A	284_D	4.661	1.00
209_I	273_I	3.669	1.00
327_E	333_E	3.630	1.00
170_Y	289_T	3.595	1.00
69_S	203_D	3.474	1.00
324_A	328_D	3.226	1.00
251_E	272_D	3.219	1.00
181_I	296_A	3.181	1.00
371_S	383_R	3.011	1.00
31_N	38_T	3.005	1.00
555_E	558_A	2.889	1.00
216_N	277_T	2.881	1.00
214_A	226_R	2.879	1.00
412_R	426_L	2.830	1.00
35_D	53_K	2.782	1.00
482_D	486_D	2.767	1.00
520_E	546_Q	2.751	1.00
115_K	144_E	2.710	1.00
339_N	342_E	2.683	1.00
410_Q	431_H	2.683	1.00
382_E	399_F	2.675	1.00
323_Q	336_K	2.541	1.00
213_L	271_Q	2.498	1.00
193_A	296_A	2.485	1.00
277_T	280_S	2.472	1.00
536_A	540_D	2.383	1.00
383_R	386_E	2.363	1.00
495_H	498_E	2.269	1.00
283_E	287_E	2.264	1.00
213_L	239_A	2.258	1.00
172_L	205_W	2.237	1.00
493_E	496_A	2.222	1.00
282_T	319_M	2.217	1.00
462_E	469_A	2.203	1.00
6_I	144_E	2.195	1.00
168_L	179_V	2.189	1.00
543_D	547_A	2.181	1.00
487_E	491_D	2.175	1.00
102_K	106_E	2.145	1.00
286_I	321_Q	2.143	1.00
7_L	18_F	2.140	1.00
290_V	329_L	2.140	1.00
168_L	181_I	2.129	1.00
316_S	319_M	2.124	1.00
534_L	576_Q	2.072	1.00
216_N	219_N	2.067	1.00
253_T	270_E	2.065	1.00
205_W	285_L	2.064	1.00
22_E	27_E	2.062	1.00
325_Q	328_D	2.053	1.00
547_A	550_D	2.041	1.00
512_A	545_V	2.037	1.00
207_H	211_D	2.014	1.00
575_K	579_Q	1.999	1.00
373_G	381_F	1.978	1.00
210_I	236_T	1.978	1.00
539_N	543_D	1.977	1.00
531_D	534_L	1.965	1.00
291_G	295_Q	1.957	1.00
500_E	504_R	1.933	1.00
490_E	494_A	1.928	1.00
49_L	96_R	1.908	1.00
414_F	426_L	1.904	1.00
497_E	501_Q	1.903	1.00
562_A	565_E	1.900	1.00
303_S	306_D	1.891	1.00
82_A	85_D	1.890	1.00
82_A	87_E	1.878	1.00
103_R	107_E	1.877	1.00
519_A	570_L	1.839	1.00
278_F	316_S	1.814	1.00
490_E	493_E	1.800	1.00
279_E	324_A	1.782	1.00
64_D	229_R	1.774	1.00
6_I	352_G	1.771	1.00
560_E	564_E	1.766	1.00
544_D	562_A	1.756	1.00
556_I	560_E	1.751	1.00
532_E	536_A	1.738	1.00
130_Q	134_D	1.727	1.00
564_E	568_D	1.708	1.00
274_T	277_T	1.704	1.00
290_V	294_E	1.689	1.00
572_E	575_K	1.684	1.00
309_D	335_K	1.682	1.00
242_A	254_V	1.677	1.00
137_E	482_D	1.664	1.00
516_I	546_Q	1.664	1.00
291_G	294_E	1.647	1.00
65_Q	84_G	1.646	1.00
19_A	349_A	1.645	1.00
100_K	104_D	1.638	1.00
567_S	571_Q	1.624	1.00
242_A	252_T	1.620	1.00
278_F	319_M	1.610	1.00
410_Q	429_D	1.607	1.00
213_L	235_L	1.596	1.00
365_V	390_A	1.591	1.00
294_E	329_L	1.590	1.00
541_A	565_E	1.587	1.00
527_E	535_E	1.586	1.00
540_D	544_D	1.584	1.00
280_S	283_E	1.582	1.00
213_L	254_V	1.582	1.00
238_A	242_A	1.577	1.00
165_Q	309_D	1.572	1.00
137_E	142_D	1.572	1.00
209_I	239_A	1.570	1.00
88_Y	93_I	1.554	1.00
294_E	298_E	1.554	1.00
486_D	490_E	1.540	1.00
412_R	429_D	1.531	1.00
318_R	341_D	1.528	1.00
282_T	286_I	1.527	1.00
240_E	244_I	1.527	1.00
36_R	342_E	1.525	1.00
96_R	99_Q	1.524	1.00
221_H	267_V	1.515	1.00
91_E	134_D	1.510	1.00
70_I	81_V	1.510	1.00
215_D	226_R	1.500	1.00
101_I	104_D	1.499	1.00
181_I	307_I	1.497	1.00
119_T	348_A	1.493	1.00
277_T	281_I	1.487	1.00
420_I	506_I	1.485	1.00
17_A	37_T	1.480	1.00
17_A	28_I	1.476	1.00
535_E	539_N	1.470	1.00
225_L	259_V	1.467	1.00
491_D	494_A	1.465	1.00
481_S	484_Q	1.465	1.00
426_L	429_D	1.464	1.00
558_A	562_A	1.462	1.00
383_R	419_E	1.454	1.00
376_V	382_E	1.452	1.00
561_T	565_E	1.447	1.00
541_A	544_D	1.445	1.00
396_S	448_T	1.444	1.00
212_H	277_T	1.439	1.00
546_Q	550_D	1.439	1.00
134_D	137_E	1.435	1.00
516_I	542_I	1.433	1.00
398_V	446_E	1.432	1.00
557_D	561_T	1.431	1.00
43_A	58_Q	1.425	1.00
368_T	451_I	1.422	1.00
166_T	183_D	1.420	1.00
295_Q	299_D	1.417	1.00
16_S	101_I	1.415	1.00
484_Q	487_E	1.410	1.00
396_S	446_E	1.396	1.00
70_I	97_I	1.396	1.00
534_L	537_D	1.392	1.00
570_L	574_G	1.380	1.00
181_I	302_L	1.379	1.00
70_I	94_S	1.378	1.00
290_V	325_Q	1.375	1.00
44_H	96_R	1.370	1.00
511_E	563_T	1.361	1.00
297_L	304_K	1.347	1.00
541_A	545_V	1.344	1.00
508_A	563_T	1.337	1.00
212_H	281_I	1.334	1.00
29_I	108_Y	1.330	1.00
205_W	278_F	1.329	1.00
92_E	96_R	1.322	1.00
67_I	93_I	1.321	1.00
215_D	218_E	1.320	1.00
326_V	334_P	1.317	1.00
212_H	271_Q	1.313	1.00
21_M	353_G	1.312	1.00
166_T	192_A	1.311	1.00
195_N	295_Q	1.310	1.00
561_T	564_E	1.306	1.00
5_K	111_Q	1.301	1.00
208_A	282_T	1.299	1.00
242_A	273_I	1.298	1.00
324_A	327_E	1.297	1.00
172_L	177_F	1.293	1.00
62_N	65_Q	1.292	1.00
136_G	146_I	1.292	1.00
70_I	93_I	1.288	1.00
420_I	423_E	1.287	1.00
381_F	414_F	1.283	1.00
444_Q	464_Q	1.280	1.00
195_N	292_P	1.279	1.00
238_A	241_E	1.275	1.00
286_I	325_Q	1.266	1.00
414_F	421_A	1.266	1.00
516_I	545_V	1.265	1.00
94_S	132_T	1.264	1.00
508_A	560_E	1.261	0.99
28_I	346_L	1.259	0.99
211_D	226_R	1.258	0.99
11_L	132_T	1.258	0.99
18_F	101_I	1.257	0.99
73_H	79_Y	1.255	0.99
42_V	93_I	1.242	0.99
253_T	272_D	1.242	0.99
295_Q	298_E	1.233	0.99
245_E	252_T	1.231	0.99
297_L	302_L	1.230	0.99
32_E	104_D	1.229	0.99
563_T	567_S	1.208	0.99
375_E	412_R	1.207	0.99
216_N	271_Q	1.205	0.99
73_H	76_E	1.203	0.99
496_A	500_E	1.203	0.99
19_A	345_A	1.200	0.99
283_E	321_Q	1.197	0.99
576_Q	579_Q	1.178	0.99
389_T	393_T	1.176	0.99
26_P	346_L	1.172	0.99
571_Q	574_G	1.169	0.99
118_I	136_G	1.169	0.99
11_L	98_L	1.168	0.99
205_W	319_M	1.162	0.99
166_T	302_L	1.160	0.99
436_P	465_G	1.158	0.99
382_E	397_K	1.157	0.99
133_K	456_I	1.156	0.99
532_E	539_N	1.154	0.99
321_Q	324_A	1.153	0.99
255_N	270_E	1.150	0.99
497_E	500_E	1.149	0.99
102_K	141_F	1.148	0.99
212_H	216_N	1.141	0.99
254_V	273_I	1.141	0.99
275_R	279_E	1.139	0.99
168_L	293_T	1.139	0.99
212_H	273_I	1.137	0.99
541_A	569_T	1.137	0.99
321_Q	325_Q	1.125	0.99
557_D	560_E	1.122	0.99
295_Q	387_K	1.121	0.99
296_A	300_A	1.120	0.99
136_G	143_V	1.120	0.99
211_D	215_D	1.119	0.99
518_R	522_L	1.115	0.99
72_R	204_D	1.110	0.99
44_H	88_Y	1.109	0.99
205_W	282_T	1.107	0.99
192_A	302_L	1.107	0.99
548_V	562_A	1.106	0.99
41_I	68_A	1.104	0.99
144_E	355_L	1.104	0.99
408_S	431_H	1.095	0.99
218_E	224_D	1.093	0.99
537_D	572_E	1.092	0.99
519_A	538_V	1.090	0.99
78_D	85_D	1.089	0.99
505_R	552_D	1.087	0.98
523_L	535_E	1.087	0.98
299_D	387_K	1.084	0.98
533_D	537_D	1.081	0.98
398_V	464_Q	1.081	0.98
572_E	576_Q	1.078	0.98
509_R	549_L	1.075	0.98
504_R	556_I	1.074	0.98
520_E	524_E	1.067	0.98
547_A	551_E	1.067	0.98
7_L	116_A	1.066	0.98
58_Q	62_N	1.066	0.98
510_N	517_Q	1.063	0.98
538_V	570_L	1.062	0.98
282_T	321_Q	1.060	0.98
488_M	491_D	1.055	0.98
531_D	576_Q	1.055	0.98
148_N	366_D	1.053	0.98
519_A	542_I	1.047	0.98
30_T	108_Y	1.045	0.98
508_A	556_I	1.040	0.98
375_E	379_G	1.040	0.98
208_A	211_D	1.037	0.98
99_Q	103_R	1.035	0.98
168_L	330_V	1.031	0.98
217_F	269_L	1.029	0.98
551_E	558_A	1.025	0.98
67_I	70_I	1.022	0.98
80_T	87_E	1.021	0.98
408_S	433_T	1.021	0.98
498_E	501_Q	1.020	0.98
394_T	448_T	1.019	0.98
293_T	329_L	1.018	0.98
71_K	149_E	1.018	0.98
43_A	50_L	1.017	0.98
183_D	192_A	1.007	0.98
21_M	26_P	1.006	0.98
327_E	334_P	1.003	0.97
30_T	36_R	1.002	0.97
70_I	74_M	1.001	0.97
238_A	252_T	1.001	0.97
536_A	539_N	1.000	0.97
76_E	79_Y	0.998	0.97
238_A	245_E	0.998	0.97
515_A	519_A	0.995	0.97
74_M	132_T	0.990	0.97
520_E	542_I	0.989	0.97
207_H	236_T	0.989	0.97
125_N	128_Q	0.985	0.97
205_W	286_I	0.984	0.97
177_F	289_T	0.984	0.97
537_D	541_A	0.982	0.97
544_D	565_E	0.982	0.97
282_T	285_L	0.982	0.97
210_I	239_A	0.981	0.97
439_P	442_T	0.980	0.97
213_L	269_L	0.979	0.97
11_L	94_S	0.979	0.97
548_V	551_E	0.977	0.97
503_R	507_E	0.977	0.97
564_E	567_S	0.973	0.97
568_D	571_Q	0.970	0.97
88_Y	96_R	0.965	0.97
208_A	285_L	0.962	0.97
13_T	175_G	0.961	0.97
137_E	489_Q	0.958	0.97
28_I	36_R	0.957	0.97
537_D	569_T	0.954	0.97
394_T	450_E	0.952	0.97
106_E	112_D	0.949	0.96
438_A	442_T	0.948	0.96
287_E	325_Q	0.945	0.96
505_R	508_A	0.945	0.96
150_P	178_D	0.943	0.96
83_L	86_D	0.942	0.96
545_V	562_A	0.942	0.96
162_D	165_Q	0.934	0.96
65_Q	83_L	0.933	0.96
182_L	191_V	0.933	0.96
371_S	417_E	0.932	0.96
44_H	83_L	0.932	0.96
228_D	231_A	0.931	0.96
428_G	474_I	0.930	0.96
149_E	178_D	0.927	0.96
452_D	458_N	0.926	0.96
214_A	232_L	0.926	0.96
234_R	238_A	0.926	0.96
36_R	339_N	0.925	0.96
209_I	212_H	0.923	0.96
126_D	130_Q	0.919	0.96
551_E	555_E	0.919	0.96
571_Q	575_K	0.915	0.96
234_R	257_P	0.912	0.96
508_A	511_E	0.910	0.95
49_L	99_Q	0.907	0.95
6_I	356_S	0.907	0.95
438_A	463_D	0.907	0.95
537_D	540_D	0.905	0.95
544_D	548_V	0.904	0.95
214_A	235_L	0.904	0.95
419_E	503_R	0.904	0.95
207_H	210_I	0.903	0.95
506_I	509_R	0.901	0.95
574_G	577_A	0.900	0.95
294_E	304_K	0.898	0.95
536_A	547_A	0.898	0.95
558_A	561_T	0.896	0.95
551_E	559_L	0.895	0.95
44_H	93_I	0.894	0.95
293_T	330_V	0.893	0.95
523_L	542_I	0.891	0.95
568_D	572_E	0.889	0.95
540_D	543_D	0.887	0.95
103_R	106_E	0.886	0.95
574_G	578_Y	0.883	0.95
95_A	138_I	0.882	0.95
292_P	296_A	0.880	0.95
335_K	343_A	0.878	0.95
515_A	563_T	0.878	0.95
213_L	273_I	0.877	0.94
260_T	265_G	0.877	0.94
129_R	148_N	0.877	0.94
181_I	300_A	0.877	0.94
510_N	514_T	0.874	0.94
195_N	198_N	0.874	0.94
43_A	62_N	0.872	0.94
148_N	151_T	0.870	0.94
513_E	549_L	0.870	0.94
302_L	306_D	0.868	0.94
279_E	282_T	0.867	0.94
134_D	480_L	0.863	0.94
409_V	445_I	0.859	0.94
401_T	406_Q	0.859	0.94
509_R	552_D	0.858	0.94
45_D	48_E	0.854	0.94
193_A	300_A	0.850	0.94
533_D	536_A	0.849	0.93
290_V	293_T	0.846	0.93
20_V	109_L	0.836	0.93
515_A	567_S	0.832	0.93
465_G	578_Y	0.829	0.93
507_E	511_E	0.822	0.92
234_R	256_L	0.820	0.92
513_E	517_Q	0.819	0.92
377_K	402_A	0.819	0.92
216_N	220_E	0.818	0.92
19_A	28_I	0.818	0.92
104_D	107_E	0.817	0.92
567_S	570_L	0.815	0.92
414_F	429_D	0.813	0.92
14_T	174_G	0.811	0.92
226_R	232_L	0.809	0.92
7_L	113_V	0.809	0.92
486_D	489_Q	0.809	0.92
122_A	178_D	0.809	0.92
367_V	388_N	0.807	0.92
565_E	568_D	0.805	0.92
529_L	580_Q	0.803	0.91
523_L	539_N	0.800	0.91
16_S	40_S	0.800	0.91
16_S	97_I	0.800	0.91
530_V	535_E	0.800	0.91
195_N	299_D	0.797	0.91
538_V	569_T	0.797	0.91
79_Y	82_A	0.797	0.91
526_N	577_A	0.796	0.91
74_M	94_S	0.796	0.91
218_E	226_R	0.794	0.91
565_E	569_T	0.790	0.91
210_I	232_L	0.789	0.91
555_E	559_L	0.789	0.91
210_I	235_L	0.788	0.91
172_L	285_L	0.788	0.91
505_R	509_R	0.785	0.91
293_T	326_V	0.785	0.91
480_L	488_M	0.783	0.90
273_I	278_F	0.782	0.90
7_L	105_A	0.780	0.90
404_D	440_A	0.780	0.90
6_I	115_K	0.777	0.90
353_G	359_V	0.776	0.90
512_A	559_L	0.775	0.90
122_A	150_P	0.774	0.90
8_G	345_A	0.774	0.90
120_V	148_N	0.771	0.90
511_E	567_S	0.770	0.90
548_V	559_L	0.767	0.89
404_D	441_G	0.766	0.89
504_R	560_E	0.766	0.89
170_Y	290_V	0.762	0.89
556_I	559_L	0.762	0.89
516_I	549_L	0.762	0.89
145_R	351_Q	0.761	0.89
197_D	200_L	0.761	0.89
325_Q	329_L	0.760	0.89
548_V	552_D	0.760	0.89
504_R	507_E	0.760	0.89
188_V	363_V	0.759	0.89
532_E	543_D	0.757	0.89
418_R	499_D	0.756	0.89
179_V	296_A	0.755	0.89
125_N	198_N	0.755	0.89
74_M	131_A	0.753	0.89
155_M	362_I	0.753	0.89
512_A	549_L	0.753	0.89
31_N	104_D	0.752	0.89
521_S	525_E	0.752	0.89
552_D	555_E	0.751	0.88
287_E	290_V	0.747	0.88
522_L	526_N	0.747	0.88
355_L	453_A	0.746	0.88
130_Q	133_K	0.745	0.88
19_A	26_P	0.744	0.88
80_T	89_T	0.743	0.88
363_V	453_A	0.743	0.88
35_D	244_I	0.743	0.88
79_Y	83_L	0.742	0.88
40_S	71_K	0.740	0.88
279_E	319_M	0.740	0.88
524_E	527_E	0.739	0.88
401_T	404_D	0.738	0.88
68_A	73_H	0.737	0.88
165_Q	308_D	0.736	0.87
446_E	462_E	0.735	0.87
71_K	175_G	0.735	0.87
175_G	178_D	0.734	0.87
548_V	558_A	0.734	0.87
438_A	443_P	0.733	0.87
89_T	97_I	0.730	0.87
166_T	308_D	0.729	0.87
22_E	108_Y	0.726	0.87
118_I	143_V	0.725	0.87
304_K	329_L	0.724	0.87
522_L	538_V	0.722	0.86
542_I	546_Q	0.720	0.86
279_E	321_Q	0.720	0.86
245_E	249_R	0.719	0.86
308_D	332_Q	0.719	0.86
144_E	352_G	0.719	0.86
405_N	571_Q	0.718	0.86
76_E	330_V	0.716	0.86
346_L	350_V	0.715	0.86
217_F	259_V	0.715	0.86
252_T	273_I	0.715	0.86
38_T	104_D	0.714	0.86
105_A	109_L	0.712	0.86
224_D	227_E	0.712	0.86
532_E	535_E	0.709	0.85
570_L	573_I	0.709	0.85
376_V	397_K	0.708	0.85
172_L	316_S	0.707	0.85
401_T	441_G	0.704	0.85
73_H	81_V	0.704	0.85
41_I	56_K	0.703	0.85
312_L	334_P	0.702	0.85
80_T	85_D	0.701	0.85
177_F	200_L	0.701	0.85
212_H	254_V	0.699	0.85
530_V	573_I	0.699	0.85
216_N	269_L	0.698	0.85
163_R	308_D	0.698	0.85
74_M	77_E	0.697	0.85
572_E	579_Q	0.697	0.85
370_L	418_R	0.696	0.84
416_G	424_N	0.696	0.84
555_E	561_T	0.696	0.84
526_N	530_V	0.695	0.84
519_A	574_G	0.695	0.84
571_Q	578_Y	0.693	0.84
118_I	132_T	0.692	0.84
197_D	291_G	0.692	0.84
199_D	293_T	0.690	0.84
76_E	198_N	0.687	0.84
241_E	244_I	0.686	0.84
150_P	176_T	0.685	0.83
545_V	559_L	0.685	0.83
135_A	139_A	0.685	0.83
511_E	516_I	0.685	0.83
534_L	538_V	0.683	0.83
13_T	71_K	0.683	0.83
247_S	320_P	0.683	0.83
102_K	116_A	0.681	0.83
273_I	277_T	0.680	0.83
62_N	66_T	0.679	0.83
45_D	50_L	0.679	0.83
92_E	488_M	0.679	0.83
379_G	422_S	0.677	0.83
465_G	577_A	0.677	0.83
119_T	344_V	0.676	0.83
159_L	311_I	0.675	0.83
60_V	233_Q	0.675	0.83
575_K	578_Y	0.674	0.82
529_L	577_A	0.674	0.82
33_E	53_K	0.673	0.82
260_T	267_V	0.672	0.82
398_V	444_Q	0.669	0.82
563_T	566_L	0.668	0.82
126_D	148_N	0.668	0.82
487_E	490_E	0.667	0.82
374_I	384_L	0.666	0.82
132_T	149_E	0.666	0.82
538_V	566_L	0.666	0.82
529_L	534_L	0.665	0.82
78_D	87_E	0.663	0.81
484_Q	488_M	0.663	0.81
278_F	285_L	0.663	0.81
125_N	425_E	0.662	0.81
7_L	352_G	0.662	0.81
98_L	132_T	0.662	0.81
172_L	289_T	0.661	0.81
309_D	337_N	0.660	0.81
463_D	466_S	0.659	0.81
569_T	572_E	0.659	0.81
67_I	83_L	0.659	0.81
24_S	358_E	0.658	0.81
86_D	92_E	0.658	0.81
286_I	322_V	0.656	0.81
258_F	266_P	0.656	0.81
8_G	12_G	0.656	0.81
133_K	146_I	0.654	0.81
9_V	118_I	0.654	0.81
61_Q	230_Q	0.654	0.81
212_H	215_D	0.654	0.81
210_I	214_A	0.654	0.81
560_E	563_T	0.653	0.80
312_L	336_K	0.653	0.80
387_K	489_Q	0.652	0.80
132_T	176_T	0.651	0.80
56_K	240_E	0.650	0.80
53_K	244_I	0.649	0.80
567_S	574_G	0.648	0.80
577_A	580_Q	0.648	0.80
15_N	69_S	0.647	0.80
351_Q	354_V	0.647	0.80
534_L	541_A	0.647	0.80
448_T	460_E	0.647	0.80
451_I	457_V	0.644	0.80
505_R	549_L	0.644	0.80
246_L	320_P	0.644	0.80
166_T	307_I	0.643	0.79
32_E	100_K	0.642	0.79
297_L	307_I	0.641	0.79
233_Q	237_E	0.641	0.79
413_V	416_G	0.640	0.79
450_E	458_N	0.639	0.79
521_S	524_E	0.638	0.79
132_T	150_P	0.638	0.79
534_L	573_I	0.638	0.79
126_D	456_I	0.638	0.79
512_A	563_T	0.638	0.79
501_Q	504_R	0.638	0.79
401_T	439_P	0.638	0.79
9_V	116_A	0.638	0.79
511_E	514_T	0.637	0.79
122_A	176_T	0.637	0.79
180_S	203_D	0.636	0.79
517_Q	520_E	0.636	0.79
573_I	576_Q	0.634	0.78
536_A	544_D	0.633	0.78
148_N	194_T	0.631	0.78
502_R	505_R	0.630	0.78
543_D	550_D	0.629	0.78
120_V	146_I	0.629	0.78
153_A	313_V	0.628	0.78
282_T	316_S	0.627	0.78
492_A	499_D	0.626	0.78
238_A	256_L	0.626	0.78
99_Q	496_A	0.626	0.78
247_S	275_R	0.625	0.78
561_T	568_D	0.625	0.78
354_V	357_G	0.624	0.77
418_R	423_E	0.624	0.77
436_P	463_D	0.622	0.77
519_A	530_V	0.622	0.77
173_G	314_G	0.620	0.77
20_V	108_Y	0.619	0.77
58_Q	66_T	0.618	0.77
68_A	76_E	0.618	0.77
195_N	296_A	0.618	0.77
512_A	516_I	0.617	0.77
434_G	468_N	0.617	0.77
132_T	178_D	0.617	0.77
446_E	464_Q	0.616	0.76
338_V	343_A	0.616	0.76
552_D	559_L	0.614	0.76
208_A	281_I	0.614	0.76
509_R	513_E	0.614	0.76
313_V	343_A	0.612	0.76
172_L	317_T	0.611	0.76
100_K	103_R	0.610	0.76
530_V	534_L	0.610	0.76
567_S	577_A	0.610	0.76
74_M	91_E	0.609	0.76
376_V	399_F	0.609	0.76
31_N	36_R	0.609	0.76
544_D	547_A	0.609	0.76
116_A	141_F	0.609	0.76
94_S	176_T	0.607	0.75
9_V	12_G	0.607	0.75
49_L	495_H	0.606	0.75
413_V	449_F	0.604	0.75
374_I	447_V	0.604	0.75
107_E	336_K	0.604	0.75
559_L	563_T	0.604	0.75
430_F	434_G	0.603	0.75
25_D	302_L	0.603	0.75
32_E	107_E	0.602	0.75
76_E	128_Q	0.601	0.75
254_V	271_Q	0.601	0.75
541_A	562_A	0.600	0.75
372_L	449_F	0.599	0.74
550_D	559_L	0.599	0.74
73_H	77_E	0.597	0.74
534_L	572_E	0.597	0.74
355_L	363_V	0.597	0.74
78_D	83_L	0.597	0.74
399_F	447_V	0.597	0.74
411_I	430_F	0.596	0.74
167_V	309_D	0.596	0.74
513_E	546_Q	0.596	0.74
368_T	372_L	0.596	0.74
102_K	112_D	0.595	0.74
217_F	221_H	0.595	0.74
10_D	13_T	0.594	0.74
543_D	546_Q	0.594	0.74
19_A	346_L	0.593	0.74
447_V	459_V	0.593	0.74
38_T	100_K	0.593	0.74
253_T	271_Q	0.592	0.74
522_L	570_L	0.592	0.74
519_A	567_S	0.592	0.74
205_W	316_S	0.592	0.74
234_R	259_V	0.591	0.74
407_T	413_V	0.591	0.74
88_Y	495_H	0.591	0.74
172_L	322_V	0.590	0.73
524_E	539_N	0.589	0.73
374_I	397_K	0.587	0.73
40_S	175_G	0.587	0.73
220_E	271_Q	0.587	0.73
13_T	176_T	0.587	0.73
153_A	344_V	0.587	0.73
20_V	29_I	0.585	0.73
258_F	268_H	0.584	0.73
376_V	380_L	0.583	0.73
516_I	566_L	0.583	0.73
302_L	307_I	0.583	0.73
542_I	545_V	0.582	0.72
297_L	300_A	0.581	0.72
318_R	342_E	0.581	0.72
91_E	131_A	0.581	0.72
523_L	530_V	0.581	0.72
260_T	266_P	0.580	0.72
539_N	547_A	0.580	0.72
543_D	549_L	0.580	0.72
223_I	267_V	0.580	0.72
14_T	345_A	0.579	0.72
505_R	556_I	0.579	0.72
386_E	389_T	0.579	0.72
517_Q	521_S	0.578	0.72
287_E	291_G	0.577	0.72
359_V	362_I	0.575	0.71
491_D	495_H	0.574	0.71
550_D	563_T	0.573	0.71
314_G	347_G	0.572	0.71
536_A	565_E	0.571	0.71
119_T	147_V	0.571	0.71
528_E	536_A	0.571	0.71
509_R	512_A	0.569	0.71
259_V	268_H	0.567	0.70
124_F	132_T	0.566	0.70
375_E	378_G	0.564	0.70
505_R	559_L	0.564	0.70
13_T	150_P	0.562	0.70
532_E	540_D	0.562	0.70
121_P	124_F	0.561	0.70
532_E	537_D	0.560	0.69
516_I	519_A	0.559	0.69
555_E	566_L	0.559	0.69
122_A	149_E	0.558	0.69
405_N	439_P	0.558	0.69
165_Q	335_K	0.558	0.69
129_R	455_G	0.558	0.69
209_I	214_A	0.556	0.69
176_T	204_D	0.556	0.69
494_A	498_E	0.555	0.69
247_S	279_E	0.554	0.69
570_L	575_K	0.554	0.69
188_V	365_V	0.553	0.69
184_L	189_Y	0.553	0.69
333_E	336_K	0.552	0.68
96_R	495_H	0.552	0.68
515_A	570_L	0.552	0.68
304_K	330_V	0.552	0.68
458_N	473_T	0.548	0.68
168_L	307_I	0.547	0.68
412_R	421_A	0.546	0.68
542_I	570_L	0.546	0.68
122_A	196_G	0.545	0.67
380_L	420_I	0.544	0.67
540_D	547_A	0.544	0.67
209_I	254_V	0.544	0.67
430_F	472_I	0.542	0.67
316_S	341_D	0.542	0.67
115_K	356_S	0.541	0.67
78_D	89_T	0.541	0.67
200_L	204_D	0.540	0.67
431_H	475_E	0.540	0.67
124_F	128_Q	0.540	0.67
86_D	301_G	0.540	0.67
381_F	424_N	0.539	0.67
148_N	455_G	0.538	0.66
492_A	495_H	0.538	0.66
217_F	267_V	0.538	0.66
237_E	241_E	0.538	0.66
538_V	573_I	0.537	0.66
234_R	258_F	0.536	0.66
38_T	101_I	0.536	0.66
19_A	352_G	0.536	0.66
522_L	534_L	0.536	0.66
298_E	301_G	0.535	0.66
522_L	527_E	0.534	0.66
257_P	266_P	0.534	0.66
68_A	74_M	0.534	0.66
346_L	349_A	0.534	0.66
560_E	568_D	0.533	0.66
541_A	549_L	0.533	0.66
501_Q	555_E	0.533	0.66
573_I	579_Q	0.533	0.66
400_T	444_Q	0.531	0.65
561_T	571_Q	0.530	0.65
83_L	88_Y	0.530	0.65
88_Y	92_E	0.530	0.65
512_A	548_V	0.528	0.65
544_D	561_T	0.526	0.65
551_E	562_A	0.526	0.65
18_F	104_D	0.526	0.65
415_Q	425_E	0.526	0.65
259_V	269_L	0.525	0.65
153_A	176_T	0.525	0.65
506_I	510_N	0.525	0.65
501_Q	557_D	0.525	0.65
448_T	462_E	0.524	0.64
449_F	457_V	0.524	0.64
312_L	326_V	0.523	0.64
67_I	81_V	0.523	0.64
92_E	138_I	0.522	0.64
509_R	571_Q	0.521	0.64
530_V	533_D	0.521	0.64
287_E	294_E	0.521	0.64
71_K	176_T	0.520	0.64
520_E	539_N	0.520	0.64
519_A	526_N	0.519	0.64
501_Q	505_R	0.519	0.64
502_R	506_I	0.518	0.64
537_D	544_D	0.518	0.64
278_F	282_T	0.517	0.63
387_K	417_E	0.516	0.63
557_D	568_D	0.516	0.63
319_M	322_V	0.516	0.63
120_V	129_R	0.515	0.63
164_D	184_L	0.514	0.63
505_R	548_V	0.514	0.63
50_L	58_Q	0.513	0.63
166_T	181_I	0.513	0.63
157_Y	343_A	0.513	0.63
403_A	407_T	0.513	0.63
385_I	389_T	0.513	0.63
250_K	275_R	0.513	0.63
275_R	324_A	0.513	0.63
94_S	98_L	0.513	0.63
536_A	543_D	0.512	0.63
21_M	24_S	0.512	0.63
71_K	94_S	0.512	0.63
567_S	575_K	0.511	0.63
217_F	260_T	0.511	0.63
375_E	414_F	0.510	0.62
275_R	320_P	0.510	0.62
577_A	581_Q	0.510	0.62
122_A	175_G	0.509	0.62
575_K	581_Q	0.509	0.62
538_V	542_I	0.509	0.62
545_V	548_V	0.509	0.62
169_V	311_I	0.509	0.62
399_F	402_A	0.508	0.62
310_V	326_V	0.507	0.62
509_R	516_I	0.506	0.62
16_S	176_T	0.505	0.62
11_L	341_D	0.505	0.62
311_I	335_K	0.504	0.61
524_E	568_D	0.504	0.61
432_L	463_D	0.502	0.61
94_S	97_I	0.502	0.61
109_L	113_V	0.501	0.61
541_A	561_T	0.501	0.61
64_D	84_G	0.501	0.61
111_Q	115_K	0.501	0.61
178_D	344_V	0.500	0.61
537_D	576_Q	0.500	0.61
65_Q	68_A	0.500	0.61
7_L	102_K	0.500	0.61
117_V	352_G	0.500	0.61

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3d2fA	1	0.9221	100	0.178	Contact Map
4jneA	2	0.9078	100	0.207	Contact Map
4fl9A	1	0.8092	100	0.238	Contact Map
2v7yA	1	0.8013	100	0.267	Contact Map
4rtfD	1	0.5517	100	0.288	Contact Map
3i33A	1	0.5533	100	0.486	Contact Map
4kboA	1	0.5564	100	0.501	Contact Map
4j8fA	2	0.8092	100	0.504	Contact Map
4gniA	2	0.5517	100	0.54	Contact Map
3qfuA	1	0.5548	100	0.555	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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