GREMLIN Database
DNAK - Chaperone protein DnaK
UniProt: Q9HRY2 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 629 (571)
Sequences: 6168 (2881)
Seq/√Len: 120.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
115_K142_D5.3171.00
197_D288_R5.0051.00
208_A284_D4.6611.00
209_I273_I3.6691.00
327_E333_E3.6301.00
170_Y289_T3.5951.00
69_S203_D3.4741.00
324_A328_D3.2261.00
251_E272_D3.2191.00
181_I296_A3.1811.00
371_S383_R3.0111.00
31_N38_T3.0051.00
555_E558_A2.8891.00
216_N277_T2.8811.00
214_A226_R2.8791.00
412_R426_L2.8301.00
35_D53_K2.7821.00
482_D486_D2.7671.00
520_E546_Q2.7511.00
115_K144_E2.7101.00
339_N342_E2.6831.00
410_Q431_H2.6831.00
382_E399_F2.6751.00
323_Q336_K2.5411.00
213_L271_Q2.4981.00
193_A296_A2.4851.00
277_T280_S2.4721.00
536_A540_D2.3831.00
383_R386_E2.3631.00
495_H498_E2.2691.00
283_E287_E2.2641.00
213_L239_A2.2581.00
172_L205_W2.2371.00
493_E496_A2.2221.00
282_T319_M2.2171.00
462_E469_A2.2031.00
6_I144_E2.1951.00
168_L179_V2.1891.00
543_D547_A2.1811.00
487_E491_D2.1751.00
102_K106_E2.1451.00
286_I321_Q2.1431.00
7_L18_F2.1401.00
290_V329_L2.1401.00
168_L181_I2.1291.00
316_S319_M2.1241.00
534_L576_Q2.0721.00
216_N219_N2.0671.00
253_T270_E2.0651.00
205_W285_L2.0641.00
22_E27_E2.0621.00
325_Q328_D2.0531.00
547_A550_D2.0411.00
512_A545_V2.0371.00
207_H211_D2.0141.00
575_K579_Q1.9991.00
373_G381_F1.9781.00
210_I236_T1.9781.00
539_N543_D1.9771.00
531_D534_L1.9651.00
291_G295_Q1.9571.00
500_E504_R1.9331.00
490_E494_A1.9281.00
49_L96_R1.9081.00
414_F426_L1.9041.00
497_E501_Q1.9031.00
562_A565_E1.9001.00
303_S306_D1.8911.00
82_A85_D1.8901.00
82_A87_E1.8781.00
103_R107_E1.8771.00
519_A570_L1.8391.00
278_F316_S1.8141.00
490_E493_E1.8001.00
279_E324_A1.7821.00
64_D229_R1.7741.00
6_I352_G1.7711.00
560_E564_E1.7661.00
544_D562_A1.7561.00
556_I560_E1.7511.00
532_E536_A1.7381.00
130_Q134_D1.7271.00
564_E568_D1.7081.00
274_T277_T1.7041.00
290_V294_E1.6891.00
572_E575_K1.6841.00
309_D335_K1.6821.00
242_A254_V1.6771.00
137_E482_D1.6641.00
516_I546_Q1.6641.00
291_G294_E1.6471.00
65_Q84_G1.6461.00
19_A349_A1.6451.00
100_K104_D1.6381.00
567_S571_Q1.6241.00
242_A252_T1.6201.00
278_F319_M1.6101.00
410_Q429_D1.6071.00
213_L235_L1.5961.00
365_V390_A1.5911.00
294_E329_L1.5901.00
541_A565_E1.5871.00
527_E535_E1.5861.00
540_D544_D1.5841.00
280_S283_E1.5821.00
213_L254_V1.5821.00
238_A242_A1.5771.00
165_Q309_D1.5721.00
137_E142_D1.5721.00
209_I239_A1.5701.00
88_Y93_I1.5541.00
294_E298_E1.5541.00
486_D490_E1.5401.00
412_R429_D1.5311.00
318_R341_D1.5281.00
282_T286_I1.5271.00
240_E244_I1.5271.00
36_R342_E1.5251.00
96_R99_Q1.5241.00
221_H267_V1.5151.00
91_E134_D1.5101.00
70_I81_V1.5101.00
215_D226_R1.5001.00
101_I104_D1.4991.00
181_I307_I1.4971.00
119_T348_A1.4931.00
277_T281_I1.4871.00
420_I506_I1.4851.00
17_A37_T1.4801.00
17_A28_I1.4761.00
535_E539_N1.4701.00
225_L259_V1.4671.00
491_D494_A1.4651.00
481_S484_Q1.4651.00
426_L429_D1.4641.00
558_A562_A1.4621.00
383_R419_E1.4541.00
376_V382_E1.4521.00
561_T565_E1.4471.00
541_A544_D1.4451.00
396_S448_T1.4441.00
212_H277_T1.4391.00
546_Q550_D1.4391.00
134_D137_E1.4351.00
516_I542_I1.4331.00
398_V446_E1.4321.00
557_D561_T1.4311.00
43_A58_Q1.4251.00
368_T451_I1.4221.00
166_T183_D1.4201.00
295_Q299_D1.4171.00
16_S101_I1.4151.00
484_Q487_E1.4101.00
396_S446_E1.3961.00
70_I97_I1.3961.00
534_L537_D1.3921.00
570_L574_G1.3801.00
181_I302_L1.3791.00
70_I94_S1.3781.00
290_V325_Q1.3751.00
44_H96_R1.3701.00
511_E563_T1.3611.00
297_L304_K1.3471.00
541_A545_V1.3441.00
508_A563_T1.3371.00
212_H281_I1.3341.00
29_I108_Y1.3301.00
205_W278_F1.3291.00
92_E96_R1.3221.00
67_I93_I1.3211.00
215_D218_E1.3201.00
326_V334_P1.3171.00
212_H271_Q1.3131.00
21_M353_G1.3121.00
166_T192_A1.3111.00
195_N295_Q1.3101.00
561_T564_E1.3061.00
5_K111_Q1.3011.00
208_A282_T1.2991.00
242_A273_I1.2981.00
324_A327_E1.2971.00
172_L177_F1.2931.00
62_N65_Q1.2921.00
136_G146_I1.2921.00
70_I93_I1.2881.00
420_I423_E1.2871.00
381_F414_F1.2831.00
444_Q464_Q1.2801.00
195_N292_P1.2791.00
238_A241_E1.2751.00
286_I325_Q1.2661.00
414_F421_A1.2661.00
516_I545_V1.2651.00
94_S132_T1.2641.00
508_A560_E1.2610.99
28_I346_L1.2590.99
211_D226_R1.2580.99
11_L132_T1.2580.99
18_F101_I1.2570.99
73_H79_Y1.2550.99
42_V93_I1.2420.99
253_T272_D1.2420.99
295_Q298_E1.2330.99
245_E252_T1.2310.99
297_L302_L1.2300.99
32_E104_D1.2290.99
563_T567_S1.2080.99
375_E412_R1.2070.99
216_N271_Q1.2050.99
73_H76_E1.2030.99
496_A500_E1.2030.99
19_A345_A1.2000.99
283_E321_Q1.1970.99
576_Q579_Q1.1780.99
389_T393_T1.1760.99
26_P346_L1.1720.99
571_Q574_G1.1690.99
118_I136_G1.1690.99
11_L98_L1.1680.99
205_W319_M1.1620.99
166_T302_L1.1600.99
436_P465_G1.1580.99
382_E397_K1.1570.99
133_K456_I1.1560.99
532_E539_N1.1540.99
321_Q324_A1.1530.99
255_N270_E1.1500.99
497_E500_E1.1490.99
102_K141_F1.1480.99
212_H216_N1.1410.99
254_V273_I1.1410.99
275_R279_E1.1390.99
168_L293_T1.1390.99
212_H273_I1.1370.99
541_A569_T1.1370.99
321_Q325_Q1.1250.99
557_D560_E1.1220.99
295_Q387_K1.1210.99
296_A300_A1.1200.99
136_G143_V1.1200.99
211_D215_D1.1190.99
518_R522_L1.1150.99
72_R204_D1.1100.99
44_H88_Y1.1090.99
205_W282_T1.1070.99
192_A302_L1.1070.99
548_V562_A1.1060.99
41_I68_A1.1040.99
144_E355_L1.1040.99
408_S431_H1.0950.99
218_E224_D1.0930.99
537_D572_E1.0920.99
519_A538_V1.0900.99
78_D85_D1.0890.99
505_R552_D1.0870.98
523_L535_E1.0870.98
299_D387_K1.0840.98
533_D537_D1.0810.98
398_V464_Q1.0810.98
572_E576_Q1.0780.98
509_R549_L1.0750.98
504_R556_I1.0740.98
520_E524_E1.0670.98
547_A551_E1.0670.98
7_L116_A1.0660.98
58_Q62_N1.0660.98
510_N517_Q1.0630.98
538_V570_L1.0620.98
282_T321_Q1.0600.98
488_M491_D1.0550.98
531_D576_Q1.0550.98
148_N366_D1.0530.98
519_A542_I1.0470.98
30_T108_Y1.0450.98
508_A556_I1.0400.98
375_E379_G1.0400.98
208_A211_D1.0370.98
99_Q103_R1.0350.98
168_L330_V1.0310.98
217_F269_L1.0290.98
551_E558_A1.0250.98
67_I70_I1.0220.98
80_T87_E1.0210.98
408_S433_T1.0210.98
498_E501_Q1.0200.98
394_T448_T1.0190.98
293_T329_L1.0180.98
71_K149_E1.0180.98
43_A50_L1.0170.98
183_D192_A1.0070.98
21_M26_P1.0060.98
327_E334_P1.0030.97
30_T36_R1.0020.97
70_I74_M1.0010.97
238_A252_T1.0010.97
536_A539_N1.0000.97
76_E79_Y0.9980.97
238_A245_E0.9980.97
515_A519_A0.9950.97
74_M132_T0.9900.97
520_E542_I0.9890.97
207_H236_T0.9890.97
125_N128_Q0.9850.97
205_W286_I0.9840.97
177_F289_T0.9840.97
537_D541_A0.9820.97
544_D565_E0.9820.97
282_T285_L0.9820.97
210_I239_A0.9810.97
439_P442_T0.9800.97
213_L269_L0.9790.97
11_L94_S0.9790.97
548_V551_E0.9770.97
503_R507_E0.9770.97
564_E567_S0.9730.97
568_D571_Q0.9700.97
88_Y96_R0.9650.97
208_A285_L0.9620.97
13_T175_G0.9610.97
137_E489_Q0.9580.97
28_I36_R0.9570.97
537_D569_T0.9540.97
394_T450_E0.9520.97
106_E112_D0.9490.96
438_A442_T0.9480.96
287_E325_Q0.9450.96
505_R508_A0.9450.96
150_P178_D0.9430.96
83_L86_D0.9420.96
545_V562_A0.9420.96
162_D165_Q0.9340.96
65_Q83_L0.9330.96
182_L191_V0.9330.96
371_S417_E0.9320.96
44_H83_L0.9320.96
228_D231_A0.9310.96
428_G474_I0.9300.96
149_E178_D0.9270.96
452_D458_N0.9260.96
214_A232_L0.9260.96
234_R238_A0.9260.96
36_R339_N0.9250.96
209_I212_H0.9230.96
126_D130_Q0.9190.96
551_E555_E0.9190.96
571_Q575_K0.9150.96
234_R257_P0.9120.96
508_A511_E0.9100.95
49_L99_Q0.9070.95
6_I356_S0.9070.95
438_A463_D0.9070.95
537_D540_D0.9050.95
544_D548_V0.9040.95
214_A235_L0.9040.95
419_E503_R0.9040.95
207_H210_I0.9030.95
506_I509_R0.9010.95
574_G577_A0.9000.95
294_E304_K0.8980.95
536_A547_A0.8980.95
558_A561_T0.8960.95
551_E559_L0.8950.95
44_H93_I0.8940.95
293_T330_V0.8930.95
523_L542_I0.8910.95
568_D572_E0.8890.95
540_D543_D0.8870.95
103_R106_E0.8860.95
574_G578_Y0.8830.95
95_A138_I0.8820.95
292_P296_A0.8800.95
335_K343_A0.8780.95
515_A563_T0.8780.95
213_L273_I0.8770.94
260_T265_G0.8770.94
129_R148_N0.8770.94
181_I300_A0.8770.94
510_N514_T0.8740.94
195_N198_N0.8740.94
43_A62_N0.8720.94
148_N151_T0.8700.94
513_E549_L0.8700.94
302_L306_D0.8680.94
279_E282_T0.8670.94
134_D480_L0.8630.94
409_V445_I0.8590.94
401_T406_Q0.8590.94
509_R552_D0.8580.94
45_D48_E0.8540.94
193_A300_A0.8500.94
533_D536_A0.8490.93
290_V293_T0.8460.93
20_V109_L0.8360.93
515_A567_S0.8320.93
465_G578_Y0.8290.93
507_E511_E0.8220.92
234_R256_L0.8200.92
513_E517_Q0.8190.92
377_K402_A0.8190.92
216_N220_E0.8180.92
19_A28_I0.8180.92
104_D107_E0.8170.92
567_S570_L0.8150.92
414_F429_D0.8130.92
14_T174_G0.8110.92
226_R232_L0.8090.92
7_L113_V0.8090.92
486_D489_Q0.8090.92
122_A178_D0.8090.92
367_V388_N0.8070.92
565_E568_D0.8050.92
529_L580_Q0.8030.91
523_L539_N0.8000.91
16_S40_S0.8000.91
16_S97_I0.8000.91
530_V535_E0.8000.91
195_N299_D0.7970.91
538_V569_T0.7970.91
79_Y82_A0.7970.91
526_N577_A0.7960.91
74_M94_S0.7960.91
218_E226_R0.7940.91
565_E569_T0.7900.91
210_I232_L0.7890.91
555_E559_L0.7890.91
210_I235_L0.7880.91
172_L285_L0.7880.91
505_R509_R0.7850.91
293_T326_V0.7850.91
480_L488_M0.7830.90
273_I278_F0.7820.90
7_L105_A0.7800.90
404_D440_A0.7800.90
6_I115_K0.7770.90
353_G359_V0.7760.90
512_A559_L0.7750.90
122_A150_P0.7740.90
8_G345_A0.7740.90
120_V148_N0.7710.90
511_E567_S0.7700.90
548_V559_L0.7670.89
404_D441_G0.7660.89
504_R560_E0.7660.89
170_Y290_V0.7620.89
556_I559_L0.7620.89
516_I549_L0.7620.89
145_R351_Q0.7610.89
197_D200_L0.7610.89
325_Q329_L0.7600.89
548_V552_D0.7600.89
504_R507_E0.7600.89
188_V363_V0.7590.89
532_E543_D0.7570.89
418_R499_D0.7560.89
179_V296_A0.7550.89
125_N198_N0.7550.89
74_M131_A0.7530.89
155_M362_I0.7530.89
512_A549_L0.7530.89
31_N104_D0.7520.89
521_S525_E0.7520.89
552_D555_E0.7510.88
287_E290_V0.7470.88
522_L526_N0.7470.88
355_L453_A0.7460.88
130_Q133_K0.7450.88
19_A26_P0.7440.88
80_T89_T0.7430.88
363_V453_A0.7430.88
35_D244_I0.7430.88
79_Y83_L0.7420.88
40_S71_K0.7400.88
279_E319_M0.7400.88
524_E527_E0.7390.88
401_T404_D0.7380.88
68_A73_H0.7370.88
165_Q308_D0.7360.87
446_E462_E0.7350.87
71_K175_G0.7350.87
175_G178_D0.7340.87
548_V558_A0.7340.87
438_A443_P0.7330.87
89_T97_I0.7300.87
166_T308_D0.7290.87
22_E108_Y0.7260.87
118_I143_V0.7250.87
304_K329_L0.7240.87
522_L538_V0.7220.86
542_I546_Q0.7200.86
279_E321_Q0.7200.86
245_E249_R0.7190.86
308_D332_Q0.7190.86
144_E352_G0.7190.86
405_N571_Q0.7180.86
76_E330_V0.7160.86
346_L350_V0.7150.86
217_F259_V0.7150.86
252_T273_I0.7150.86
38_T104_D0.7140.86
105_A109_L0.7120.86
224_D227_E0.7120.86
532_E535_E0.7090.85
570_L573_I0.7090.85
376_V397_K0.7080.85
172_L316_S0.7070.85
401_T441_G0.7040.85
73_H81_V0.7040.85
41_I56_K0.7030.85
312_L334_P0.7020.85
80_T85_D0.7010.85
177_F200_L0.7010.85
212_H254_V0.6990.85
530_V573_I0.6990.85
216_N269_L0.6980.85
163_R308_D0.6980.85
74_M77_E0.6970.85
572_E579_Q0.6970.85
370_L418_R0.6960.84
416_G424_N0.6960.84
555_E561_T0.6960.84
526_N530_V0.6950.84
519_A574_G0.6950.84
571_Q578_Y0.6930.84
118_I132_T0.6920.84
197_D291_G0.6920.84
199_D293_T0.6900.84
76_E198_N0.6870.84
241_E244_I0.6860.84
150_P176_T0.6850.83
545_V559_L0.6850.83
135_A139_A0.6850.83
511_E516_I0.6850.83
534_L538_V0.6830.83
13_T71_K0.6830.83
247_S320_P0.6830.83
102_K116_A0.6810.83
273_I277_T0.6800.83
62_N66_T0.6790.83
45_D50_L0.6790.83
92_E488_M0.6790.83
379_G422_S0.6770.83
465_G577_A0.6770.83
119_T344_V0.6760.83
159_L311_I0.6750.83
60_V233_Q0.6750.83
575_K578_Y0.6740.82
529_L577_A0.6740.82
33_E53_K0.6730.82
260_T267_V0.6720.82
398_V444_Q0.6690.82
563_T566_L0.6680.82
126_D148_N0.6680.82
487_E490_E0.6670.82
374_I384_L0.6660.82
132_T149_E0.6660.82
538_V566_L0.6660.82
529_L534_L0.6650.82
78_D87_E0.6630.81
484_Q488_M0.6630.81
278_F285_L0.6630.81
125_N425_E0.6620.81
7_L352_G0.6620.81
98_L132_T0.6620.81
172_L289_T0.6610.81
309_D337_N0.6600.81
463_D466_S0.6590.81
569_T572_E0.6590.81
67_I83_L0.6590.81
24_S358_E0.6580.81
86_D92_E0.6580.81
286_I322_V0.6560.81
258_F266_P0.6560.81
8_G12_G0.6560.81
133_K146_I0.6540.81
9_V118_I0.6540.81
61_Q230_Q0.6540.81
212_H215_D0.6540.81
210_I214_A0.6540.81
560_E563_T0.6530.80
312_L336_K0.6530.80
387_K489_Q0.6520.80
132_T176_T0.6510.80
56_K240_E0.6500.80
53_K244_I0.6490.80
567_S574_G0.6480.80
577_A580_Q0.6480.80
15_N69_S0.6470.80
351_Q354_V0.6470.80
534_L541_A0.6470.80
448_T460_E0.6470.80
451_I457_V0.6440.80
505_R549_L0.6440.80
246_L320_P0.6440.80
166_T307_I0.6430.79
32_E100_K0.6420.79
297_L307_I0.6410.79
233_Q237_E0.6410.79
413_V416_G0.6400.79
450_E458_N0.6390.79
521_S524_E0.6380.79
132_T150_P0.6380.79
534_L573_I0.6380.79
126_D456_I0.6380.79
512_A563_T0.6380.79
501_Q504_R0.6380.79
401_T439_P0.6380.79
9_V116_A0.6380.79
511_E514_T0.6370.79
122_A176_T0.6370.79
180_S203_D0.6360.79
517_Q520_E0.6360.79
573_I576_Q0.6340.78
536_A544_D0.6330.78
148_N194_T0.6310.78
502_R505_R0.6300.78
543_D550_D0.6290.78
120_V146_I0.6290.78
153_A313_V0.6280.78
282_T316_S0.6270.78
492_A499_D0.6260.78
238_A256_L0.6260.78
99_Q496_A0.6260.78
247_S275_R0.6250.78
561_T568_D0.6250.78
354_V357_G0.6240.77
418_R423_E0.6240.77
436_P463_D0.6220.77
519_A530_V0.6220.77
173_G314_G0.6200.77
20_V108_Y0.6190.77
58_Q66_T0.6180.77
68_A76_E0.6180.77
195_N296_A0.6180.77
512_A516_I0.6170.77
434_G468_N0.6170.77
132_T178_D0.6170.77
446_E464_Q0.6160.76
338_V343_A0.6160.76
552_D559_L0.6140.76
208_A281_I0.6140.76
509_R513_E0.6140.76
313_V343_A0.6120.76
172_L317_T0.6110.76
100_K103_R0.6100.76
530_V534_L0.6100.76
567_S577_A0.6100.76
74_M91_E0.6090.76
376_V399_F0.6090.76
31_N36_R0.6090.76
544_D547_A0.6090.76
116_A141_F0.6090.76
94_S176_T0.6070.75
9_V12_G0.6070.75
49_L495_H0.6060.75
413_V449_F0.6040.75
374_I447_V0.6040.75
107_E336_K0.6040.75
559_L563_T0.6040.75
430_F434_G0.6030.75
25_D302_L0.6030.75
32_E107_E0.6020.75
76_E128_Q0.6010.75
254_V271_Q0.6010.75
541_A562_A0.6000.75
372_L449_F0.5990.74
550_D559_L0.5990.74
73_H77_E0.5970.74
534_L572_E0.5970.74
355_L363_V0.5970.74
78_D83_L0.5970.74
399_F447_V0.5970.74
411_I430_F0.5960.74
167_V309_D0.5960.74
513_E546_Q0.5960.74
368_T372_L0.5960.74
102_K112_D0.5950.74
217_F221_H0.5950.74
10_D13_T0.5940.74
543_D546_Q0.5940.74
19_A346_L0.5930.74
447_V459_V0.5930.74
38_T100_K0.5930.74
253_T271_Q0.5920.74
522_L570_L0.5920.74
519_A567_S0.5920.74
205_W316_S0.5920.74
234_R259_V0.5910.74
407_T413_V0.5910.74
88_Y495_H0.5910.74
172_L322_V0.5900.73
524_E539_N0.5890.73
374_I397_K0.5870.73
40_S175_G0.5870.73
220_E271_Q0.5870.73
13_T176_T0.5870.73
153_A344_V0.5870.73
20_V29_I0.5850.73
258_F268_H0.5840.73
376_V380_L0.5830.73
516_I566_L0.5830.73
302_L307_I0.5830.73
542_I545_V0.5820.72
297_L300_A0.5810.72
318_R342_E0.5810.72
91_E131_A0.5810.72
523_L530_V0.5810.72
260_T266_P0.5800.72
539_N547_A0.5800.72
543_D549_L0.5800.72
223_I267_V0.5800.72
14_T345_A0.5790.72
505_R556_I0.5790.72
386_E389_T0.5790.72
517_Q521_S0.5780.72
287_E291_G0.5770.72
359_V362_I0.5750.71
491_D495_H0.5740.71
550_D563_T0.5730.71
314_G347_G0.5720.71
536_A565_E0.5710.71
119_T147_V0.5710.71
528_E536_A0.5710.71
509_R512_A0.5690.71
259_V268_H0.5670.70
124_F132_T0.5660.70
375_E378_G0.5640.70
505_R559_L0.5640.70
13_T150_P0.5620.70
532_E540_D0.5620.70
121_P124_F0.5610.70
532_E537_D0.5600.69
516_I519_A0.5590.69
555_E566_L0.5590.69
122_A149_E0.5580.69
405_N439_P0.5580.69
165_Q335_K0.5580.69
129_R455_G0.5580.69
209_I214_A0.5560.69
176_T204_D0.5560.69
494_A498_E0.5550.69
247_S279_E0.5540.69
570_L575_K0.5540.69
188_V365_V0.5530.69
184_L189_Y0.5530.69
333_E336_K0.5520.68
96_R495_H0.5520.68
515_A570_L0.5520.68
304_K330_V0.5520.68
458_N473_T0.5480.68
168_L307_I0.5470.68
412_R421_A0.5460.68
542_I570_L0.5460.68
122_A196_G0.5450.67
380_L420_I0.5440.67
540_D547_A0.5440.67
209_I254_V0.5440.67
430_F472_I0.5420.67
316_S341_D0.5420.67
115_K356_S0.5410.67
78_D89_T0.5410.67
200_L204_D0.5400.67
431_H475_E0.5400.67
124_F128_Q0.5400.67
86_D301_G0.5400.67
381_F424_N0.5390.67
148_N455_G0.5380.66
492_A495_H0.5380.66
217_F267_V0.5380.66
237_E241_E0.5380.66
538_V573_I0.5370.66
234_R258_F0.5360.66
38_T101_I0.5360.66
19_A352_G0.5360.66
522_L534_L0.5360.66
298_E301_G0.5350.66
522_L527_E0.5340.66
257_P266_P0.5340.66
68_A74_M0.5340.66
346_L349_A0.5340.66
560_E568_D0.5330.66
541_A549_L0.5330.66
501_Q555_E0.5330.66
573_I579_Q0.5330.66
400_T444_Q0.5310.65
561_T571_Q0.5300.65
83_L88_Y0.5300.65
88_Y92_E0.5300.65
512_A548_V0.5280.65
544_D561_T0.5260.65
551_E562_A0.5260.65
18_F104_D0.5260.65
415_Q425_E0.5260.65
259_V269_L0.5250.65
153_A176_T0.5250.65
506_I510_N0.5250.65
501_Q557_D0.5250.65
448_T462_E0.5240.64
449_F457_V0.5240.64
312_L326_V0.5230.64
67_I81_V0.5230.64
92_E138_I0.5220.64
509_R571_Q0.5210.64
530_V533_D0.5210.64
287_E294_E0.5210.64
71_K176_T0.5200.64
520_E539_N0.5200.64
519_A526_N0.5190.64
501_Q505_R0.5190.64
502_R506_I0.5180.64
537_D544_D0.5180.64
278_F282_T0.5170.63
387_K417_E0.5160.63
557_D568_D0.5160.63
319_M322_V0.5160.63
120_V129_R0.5150.63
164_D184_L0.5140.63
505_R548_V0.5140.63
50_L58_Q0.5130.63
166_T181_I0.5130.63
157_Y343_A0.5130.63
403_A407_T0.5130.63
385_I389_T0.5130.63
250_K275_R0.5130.63
275_R324_A0.5130.63
94_S98_L0.5130.63
536_A543_D0.5120.63
21_M24_S0.5120.63
71_K94_S0.5120.63
567_S575_K0.5110.63
217_F260_T0.5110.63
375_E414_F0.5100.62
275_R320_P0.5100.62
577_A581_Q0.5100.62
122_A175_G0.5090.62
575_K581_Q0.5090.62
538_V542_I0.5090.62
545_V548_V0.5090.62
169_V311_I0.5090.62
399_F402_A0.5080.62
310_V326_V0.5070.62
509_R516_I0.5060.62
16_S176_T0.5050.62
11_L341_D0.5050.62
311_I335_K0.5040.61
524_E568_D0.5040.61
432_L463_D0.5020.61
94_S97_I0.5020.61
109_L113_V0.5010.61
541_A561_T0.5010.61
64_D84_G0.5010.61
111_Q115_K0.5010.61
178_D344_V0.5000.61
537_D576_Q0.5000.61
65_Q68_A0.5000.61
7_L102_K0.5000.61
117_V352_G0.5000.61
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3d2fA 1 0.9221 100 0.178 Contact Map
4jneA 2 0.9078 100 0.207 Contact Map
4fl9A 1 0.8092 100 0.238 Contact Map
2v7yA 1 0.8013 100 0.267 Contact Map
4rtfD 1 0.5517 100 0.288 Contact Map
3i33A 1 0.5533 100 0.486 Contact Map
4kboA 1 0.5564 100 0.501 Contact Map
4j8fA 2 0.8092 100 0.504 Contact Map
4gniA 2 0.5517 100 0.54 Contact Map
3qfuA 1 0.5548 100 0.555 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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