Q9HRV9 - HALSA - GREMLIN Contacts

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Q9HRV9 - DNA polymerase

UniProt:	Q9HRV9	Sequences: MGNTELSEFMHESDGADDPGEDAIQEEAAVVAGDADPVVNEVLTAEADALPDATGEVELMVTQVDYTIEGSGDRERPVLHVFGRTTDDEAEHVRVHGFRPYFYAPTATLSEDDLTDDVITGTEDGYESIRGEALTKIFGRTPRDVGNIRDAFDHYEADILFPNRLLIDKDITDGVRVPARRADDGALYVHHDEIAACEVAADLRVNTFDIEVNDRNGFPEDGEEPVVCLTSHDSYRDEYVAWLYAAPDATVDAPTAVPGYDPLTDDADIDVRVFDTEEAMHDAFLSYIEDTNPDVLTGWNFDDFDAPYLIDRLDELDPRTDHDLDSDRLSRVSEVWTSGWGGPNVKGRVVFDLLYAYQRTKYSELDSYRLDAVGEQELGVGKERYPGDIGDLWEDDPERLLEYNLRDVELCVEIDRKQSIVAFWDEARKLVGCKLEDATTPGDAVDMYVLHKAFGNFVLPSKGQQDAEEFEGGAVFDPITGVRENVSVLDLKSLYPMSMVTINASPETKVDPEEFDGDTYRTPTGVHFRKEPDGIIREMVDELLTEREEKKARRDDHEPDSEDYERYDRQQAAVKVIMNSLYGVFGWDRFRLYDRAMSAGVTSTNREVIDFTEQAAEEFGYEVAYGDTDSVMLELGDDMTKAEAIAESFDIEDHINAAYDEFAREQLHADDHRFQIEFEKLYRRFFQAGKKKRYAGHIVWKEGKDVDDVDITGFEYQRSDIAPITKRVQKEVIDLVVREGDVDAVEEYVHGVIEEFQEGDADLDDIGIPGGIGKRLDNYETDTAQVRGAKYANLLLGTNFDRGSKPKRLYLAKVHPDFWGHVEDEQGIDTSTSDRYREFRRDPDVICYEYADQIPDTFVVDYDKMLDKTLKGPIERILEALDLSWDEVKSGQTQTGLGQFT	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	901 (758)
Sequences:	1884 (1091)
Seq/√Len:	39.6

ECOLI - DPO2
HALSA - Q9HRV9 Q9HHJ8
SULSO - DPOL1 DPOL3 DPOL2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
229_L	284_F	6.974	1.00
479_I	622_E	6.837	1.00
727_R	765_D	6.474	1.00
755_E	760_D	5.716	1.00
640_T	643_E	5.575	1.00
380_V	413_E	5.365	1.00
226_V	309_L	5.039	1.00
101_Y	168_D	4.821	1.00
139_G	148_I	4.170	1.00
756_F	766_I	3.992	1.00
751_G	755_E	3.884	1.00
533_D	541_D	3.612	1.00
208_F	284_F	3.585	1.00
272_R	283_A	3.469	1.00
288_I	296_L	3.459	1.00
728_V	752_V	3.386	1.00
643_E	646_A	3.368	1.00
276_T	279_A	3.246	1.00
731_E	735_L	3.186	1.00
194_I	197_C	3.150	1.00
210_I	229_L	3.149	1.00
614_Q	618_E	3.076	1.00
283_A	286_S	3.054	1.00
274_F	283_A	2.855	1.00
558_E	563_D	2.800	1.00
432_G	451_H	2.787	1.00
193_E	196_A	2.738	1.00
380_V	406_R	2.723	1.00
613_E	617_E	2.722	1.00
682_Y	710_D	2.711	1.00
278_E	282_D	2.692	1.00
305_D	407_D	2.678	1.00
277_E	312_R	2.662	1.00
730_K	734_D	2.621	1.00
520_Y	523_P	2.618	1.00
375_E	381_G	2.610	1.00
809_L	860_V	2.606	1.00
300_N	305_D	2.565	1.00
757_Q	863_D	2.525	1.00
840_R	843_P	2.500	1.00
161_F	168_D	2.487	1.00
646_A	650_D	2.445	1.00
455_G	538_E	2.423	1.00
191_H	194_I	2.345	1.00
863_D	867_D	2.314	1.00
211_E	407_D	2.235	1.00
695_A	714_F	2.229	1.00
841_R	845_V	2.229	1.00
837_R	840_R	2.229	1.00
230_T	408_V	2.225	0.99
619_F	654_H	2.218	0.99
154_H	157_A	2.216	0.99
203_L	295_V	2.213	0.99
650_D	654_H	2.211	0.99
747_E	751_G	2.200	0.99
193_E	197_C	2.194	0.99
391_D	395_D	2.193	0.99
452_K	542_E	2.190	0.99
184_D	188_Y	2.179	0.99
843_P	847_C	2.175	0.99
406_R	409_E	2.164	0.99
552_A	555_D	2.152	0.99
292_N	348_R	2.148	0.99
142_P	161_F	2.129	0.99
228_C	231_S	2.121	0.99
374_G	410_L	2.116	0.99
654_H	657_A	2.112	0.99
121_G	456_N	2.087	0.99
191_H	195_A	2.081	0.99
206_N	231_S	2.079	0.99
184_D	197_C	2.077	0.99
838_E	841_R	2.053	0.99
652_E	656_N	2.033	0.99
528_F	600_G	2.024	0.99
472_G	475_V	2.010	0.99
388_D	391_D	2.007	0.99
209_D	403_Y	1.963	0.99
211_E	305_D	1.962	0.99
715_E	876_R	1.954	0.99
448_Y	577_I	1.952	0.99
839_F	843_P	1.941	0.99
298_G	301_F	1.940	0.99
734_D	738_R	1.913	0.98
553_R	567_Y	1.909	0.98
100_P	156_E	1.907	0.98
207_T	411_C	1.904	0.98
188_Y	194_I	1.903	0.98
680_K	710_D	1.901	0.98
184_D	194_I	1.861	0.98
842_D	845_V	1.850	0.98
311_D	314_D	1.834	0.98
453_A	535_I	1.823	0.98
810_Y	864_K	1.821	0.98
136_K	168_D	1.807	0.98
77_P	100_P	1.805	0.98
292_N	326_S	1.804	0.98
205_V	295_V	1.792	0.98
791_Y	845_V	1.781	0.98
160_L	163_N	1.781	0.98
754_E	758_E	1.778	0.97
278_E	316_L	1.778	0.97
561_S	564_Y	1.774	0.97
769_P	805_K	1.766	0.97
95_V	165_L	1.756	0.97
190_H	194_I	1.753	0.97
622_E	634_E	1.742	0.97
382_K	407_D	1.709	0.97
611_F	614_Q	1.701	0.97
502_I	608_V	1.691	0.97
300_N	304_F	1.674	0.96
518_D	523_P	1.671	0.96
211_E	300_N	1.668	0.96
839_F	842_D	1.662	0.96
700_W	703_G	1.661	0.96
492_K	677_E	1.651	0.96
295_V	421_V	1.650	0.96
209_D	407_D	1.644	0.96
844_D	847_C	1.637	0.96
547_R	571_Q	1.634	0.96
626_G	630_S	1.632	0.96
326_S	348_R	1.631	0.96
209_D	305_D	1.629	0.96
285_L	289_E	1.623	0.96
735_L	744_A	1.618	0.96
838_E	842_D	1.618	0.96
541_D	545_T	1.616	0.96
748_Y	752_V	1.616	0.96
407_D	602_T	1.614	0.96
211_E	403_Y	1.610	0.95
653_D	657_A	1.605	0.95
837_R	841_R	1.601	0.95
536_I	585_F	1.593	0.95
534_G	537_R	1.589	0.95
787_R	791_Y	1.578	0.95
488_V	632_M	1.576	0.95
503_N	508_T	1.569	0.95
349_V	435_L	1.569	0.95
637_D	644_A	1.566	0.95
305_D	382_K	1.565	0.95
717_Q	785_Q	1.565	0.95
228_C	401_L	1.562	0.95
731_E	734_D	1.557	0.95
142_P	168_D	1.555	0.94
142_P	145_V	1.552	0.94
615_A	658_A	1.550	0.94
475_V	691_K	1.547	0.94
452_K	455_G	1.547	0.94
441_P	444_A	1.543	0.94
79_L	165_L	1.542	0.94
839_F	861_D	1.540	0.94
460_P	464_Q	1.539	0.94
164_R	168_D	1.539	0.94
453_A	507_E	1.535	0.94
503_N	534_G	1.532	0.94
434_K	437_D	1.532	0.94
627_D	692_K	1.520	0.94
590_F	593_Y	1.520	0.94
812_A	859_V	1.511	0.94
407_D	472_G	1.507	0.93
300_N	407_D	1.506	0.93
114_L	117_D	1.504	0.93
701_K	704_K	1.501	0.93
472_G	602_T	1.501	0.93
357_Y	360_T	1.494	0.93
680_K	696_G	1.488	0.93
491_L	497_M	1.485	0.93
516_D	519_T	1.483	0.93
598_S	605_N	1.480	0.93
610_D	614_Q	1.478	0.93
615_A	618_E	1.478	0.93
248_D	252_D	1.470	0.93
840_R	845_V	1.465	0.92
300_N	354_L	1.463	0.92
105_P	155_Y	1.462	0.92
582_Y	598_S	1.455	0.92
775_R	778_N	1.455	0.92
839_F	844_D	1.455	0.92
450_L	459_L	1.442	0.92
656_N	659_Y	1.440	0.92
755_E	761_A	1.439	0.92
543_L	574_V	1.439	0.92
493_S	576_V	1.437	0.92
564_Y	568_D	1.430	0.92
728_V	748_Y	1.426	0.91
424_W	435_L	1.422	0.91
210_I	226_V	1.420	0.91
232_H	412_V	1.420	0.91
427_A	573_A	1.418	0.91
274_F	280_M	1.417	0.91
250_T	254_P	1.411	0.91
119_I	123_E	1.403	0.91
282_D	286_S	1.402	0.91
118_V	121_G	1.402	0.91
772_I	786_V	1.400	0.91
168_D	456_N	1.387	0.90
390_G	394_E	1.387	0.90
124_D	136_K	1.385	0.90
746_E	884_S	1.372	0.90
609_I	631_V	1.362	0.89
80_H	94_R	1.358	0.89
211_E	304_F	1.357	0.89
251_V	254_P	1.354	0.89
384_R	407_D	1.342	0.89
615_A	655_I	1.339	0.89
560_D	563_D	1.337	0.89
211_E	382_K	1.331	0.88
366_D	726_K	1.329	0.88
304_F	407_D	1.328	0.88
695_A	737_V	1.327	0.88
192_D	196_A	1.325	0.88
515_F	518_D	1.322	0.88
249_A	252_D	1.320	0.88
842_D	847_C	1.314	0.88
871_K	886_D	1.306	0.87
126_Y	129_I	1.305	0.87
617_E	622_E	1.303	0.87
526_V	600_G	1.300	0.87
294_D	348_R	1.298	0.87
206_N	288_I	1.297	0.87
488_V	696_G	1.295	0.87
842_D	846_I	1.292	0.87
367_S	372_A	1.292	0.87
120_T	131_G	1.289	0.87
544_L	578_M	1.285	0.86
549_E	552_A	1.276	0.86
725_T	873_P	1.276	0.86
810_Y	840_R	1.275	0.86
77_P	142_P	1.272	0.86
534_G	538_E	1.269	0.86
335_V	340_W	1.267	0.86
355_Y	358_Q	1.266	0.86
785_Q	808_R	1.256	0.85
214_D	390_G	1.252	0.85
139_G	145_V	1.248	0.85
742_V	745_V	1.248	0.85
191_H	196_A	1.245	0.85
102_F	148_I	1.244	0.85
554_R	568_D	1.243	0.85
106_T	135_T	1.239	0.84
700_W	704_K	1.236	0.84
281_H	313_L	1.236	0.84
102_F	568_D	1.235	0.84
352_D	472_G	1.223	0.84
444_A	590_F	1.220	0.83
838_E	843_P	1.220	0.83
446_D	587_W	1.219	0.83
191_H	197_C	1.218	0.83
403_Y	407_D	1.214	0.83
156_E	168_D	1.214	0.83
843_P	846_I	1.210	0.83
371_D	381_G	1.210	0.83
502_I	674_F	1.208	0.83
715_E	718_R	1.208	0.83
101_Y	136_K	1.207	0.83
488_V	680_K	1.206	0.83
118_V	122_T	1.205	0.83
234_S	412_V	1.204	0.83
77_P	161_F	1.197	0.82
722_A	869_T	1.195	0.82
789_A	861_D	1.192	0.82
171_I	672_H	1.190	0.82
230_T	404_N	1.187	0.82
728_V	732_V	1.187	0.82
335_V	342_G	1.184	0.82
837_R	842_D	1.184	0.82
382_K	403_Y	1.184	0.82
382_K	410_L	1.183	0.81
550_K	574_V	1.181	0.81
840_R	844_D	1.179	0.81
334_E	338_S	1.176	0.81
649_F	653_D	1.176	0.81
334_E	337_T	1.172	0.81
299_W	414_I	1.172	0.81
776_L	790_K	1.170	0.81
174_G	425_D	1.167	0.81
292_N	432_G	1.167	0.81
101_Y	142_P	1.159	0.80
391_D	394_E	1.159	0.80
840_R	847_C	1.156	0.80
405_L	676_I	1.152	0.80
188_Y	191_H	1.148	0.79
655_I	676_I	1.146	0.79
518_D	522_T	1.144	0.79
655_I	793_N	1.141	0.79
358_Q	368_Y	1.133	0.79
356_A	360_T	1.131	0.78
557_H	560_D	1.131	0.78
142_P	157_A	1.123	0.78
839_F	847_C	1.122	0.78
122_T	131_G	1.121	0.78
741_D	744_A	1.119	0.78
642_A	646_A	1.119	0.78
174_G	722_A	1.105	0.77
483_R	497_M	1.104	0.77
800_F	805_K	1.103	0.77
874_I	878_L	1.102	0.77
305_D	403_Y	1.098	0.76
486_V	792_A	1.092	0.76
370_L	573_A	1.091	0.76
635_L	647_E	1.091	0.76
159_I	450_L	1.085	0.75
308_Y	312_R	1.082	0.75
226_V	248_D	1.082	0.75
101_Y	164_R	1.077	0.75
586_G	598_S	1.077	0.75
80_H	92_H	1.076	0.75
492_K	537_R	1.075	0.75
427_A	431_V	1.074	0.75
426_E	570_Q	1.072	0.75
575_K	583_G	1.071	0.75
231_S	284_F	1.069	0.74
286_S	289_E	1.066	0.74
210_I	300_N	1.064	0.74
400_L	430_L	1.061	0.74
102_F	145_V	1.060	0.74
118_V	123_E	1.060	0.74
188_Y	197_C	1.060	0.74
749_V	866_L	1.059	0.74
409_E	413_E	1.059	0.74
149_R	152_F	1.058	0.74
645_I	678_F	1.058	0.74
723_P	727_R	1.058	0.74
188_Y	195_A	1.058	0.74
81_V	165_L	1.057	0.74
426_E	429_K	1.051	0.73
431_V	685_F	1.045	0.73
460_P	463_G	1.045	0.73
184_D	193_E	1.044	0.73
105_P	132_E	1.043	0.73
731_E	748_Y	1.042	0.72
104_A	154_H	1.039	0.72
480_T	603_S	1.037	0.72
578_M	719_S	1.034	0.72
797_G	800_F	1.033	0.72
204_R	291_T	1.031	0.72
137_I	142_P	1.030	0.72
77_P	80_H	1.030	0.72
304_F	354_L	1.029	0.72
353_L	411_C	1.029	0.72
756_F	870_L	1.029	0.72
788_G	840_R	1.028	0.71
147_N	646_A	1.025	0.71
480_T	689_G	1.025	0.71
209_D	382_K	1.023	0.71
419_S	422_A	1.022	0.71
80_H	83_G	1.019	0.71
370_L	407_D	1.016	0.71
417_K	499_M	1.014	0.70
518_D	521_R	1.013	0.70
627_D	691_K	1.012	0.70
546_E	549_E	1.011	0.70
104_A	134_L	1.010	0.70
697_H	738_R	1.010	0.70
795_L	800_F	1.007	0.70
253_A	275_D	1.005	0.70
294_D	347_G	1.001	0.69
189_V	486_V	1.000	0.69
171_I	395_D	0.997	0.69
275_D	642_A	0.997	0.69
76_R	80_H	0.997	0.69
137_I	148_I	0.996	0.69
366_D	372_A	0.995	0.69
209_D	304_F	0.994	0.69
184_D	196_A	0.994	0.69
839_F	845_V	0.992	0.69
470_F	475_V	0.992	0.69
608_V	612_T	0.992	0.69
77_P	83_G	0.992	0.69
345_V	420_I	0.991	0.69
156_E	159_I	0.991	0.69
328_R	734_D	0.988	0.68
498_S	608_V	0.988	0.68
100_P	142_P	0.987	0.68
568_D	571_Q	0.987	0.68
369_R	374_G	0.987	0.68
508_T	534_G	0.987	0.68
396_D	624_A	0.986	0.68
552_A	653_D	0.984	0.68
686_F	695_A	0.983	0.68
358_Q	771_G	0.978	0.68
148_I	152_F	0.976	0.67
294_D	326_S	0.975	0.67
207_T	408_V	0.974	0.67
414_I	475_V	0.972	0.67
864_K	876_R	0.972	0.67
492_K	576_V	0.970	0.67
866_L	871_K	0.970	0.67
501_T	673_R	0.968	0.67
407_D	410_L	0.967	0.67
842_D	862_Y	0.965	0.67
554_R	564_Y	0.964	0.66
378_L	410_L	0.963	0.66
452_K	539_M	0.963	0.66
349_V	450_L	0.963	0.66
211_E	370_L	0.961	0.66
233_D	291_T	0.960	0.66
436_E	440_T	0.957	0.66
793_N	799_N	0.955	0.66
403_Y	410_L	0.952	0.65
463_G	870_L	0.947	0.65
310_I	314_D	0.946	0.65
837_R	843_P	0.946	0.65
446_D	591_R	0.946	0.65
502_I	609_I	0.945	0.65
486_V	634_E	0.942	0.65
504_A	522_T	0.941	0.65
192_D	195_A	0.937	0.64
324_L	332_V	0.937	0.64
78_V	94_R	0.936	0.64
743_D	747_E	0.936	0.64
747_E	750_H	0.931	0.64
477_D	500_V	0.931	0.64
458_V	614_Q	0.929	0.64
485_N	593_Y	0.928	0.63
516_D	520_Y	0.927	0.63
693_R	715_E	0.926	0.63
717_Q	810_Y	0.926	0.63
348_R	623_V	0.923	0.63
327_D	330_S	0.921	0.63
715_E	729_Q	0.920	0.63
336_W	340_W	0.919	0.63
370_L	472_G	0.916	0.62
580_S	602_T	0.915	0.62
586_G	630_S	0.915	0.62
209_D	300_N	0.913	0.62
93_V	177_V	0.912	0.62
800_F	804_S	0.911	0.62
591_R	715_E	0.911	0.62
305_D	354_L	0.910	0.62
591_R	876_R	0.910	0.62
383_E	399_R	0.908	0.62
582_Y	712_T	0.907	0.62
720_D	770_G	0.906	0.62
385_Y	392_L	0.906	0.62
100_P	157_A	0.904	0.61
150_D	517_G	0.904	0.61
632_M	696_G	0.904	0.61
316_L	458_V	0.901	0.61
838_E	844_D	0.901	0.61
275_D	278_E	0.900	0.61
104_A	137_I	0.900	0.61
611_F	615_A	0.899	0.61
300_N	374_G	0.899	0.61
144_D	148_I	0.898	0.61
173_D	432_G	0.897	0.61
793_N	800_F	0.896	0.61
608_V	674_F	0.893	0.60
85_T	88_D	0.891	0.60
755_E	844_D	0.890	0.60
497_M	550_K	0.889	0.60
249_A	287_Y	0.887	0.60
558_E	567_Y	0.886	0.60
353_L	601_V	0.886	0.60
299_W	373_V	0.884	0.60
208_F	306_A	0.881	0.59
86_T	199_V	0.881	0.59
442_G	447_M	0.878	0.59
763_L	860_V	0.878	0.59
455_G	535_I	0.876	0.59
328_R	331_R	0.876	0.59
174_G	869_T	0.876	0.59
288_I	614_Q	0.874	0.59
735_L	738_R	0.873	0.59
790_K	793_N	0.871	0.59
211_E	472_G	0.871	0.59
282_D	318_P	0.869	0.58
625_Y	630_S	0.868	0.58
501_T	656_N	0.864	0.58
493_S	630_S	0.864	0.58
807_K	842_D	0.864	0.58
101_Y	161_F	0.863	0.58
222_G	311_D	0.863	0.58
498_S	674_F	0.862	0.58
392_L	399_R	0.860	0.58
721_I	872_G	0.859	0.57
558_E	561_S	0.859	0.57
612_T	631_V	0.858	0.57
195_A	727_R	0.858	0.57
323_D	328_R	0.858	0.57
444_A	593_Y	0.857	0.57
76_R	96_H	0.857	0.57
520_Y	604_T	0.853	0.57
278_E	318_P	0.849	0.57
721_I	725_T	0.849	0.57
113_D	117_D	0.849	0.57
687_Q	712_T	0.848	0.56
78_V	96_H	0.847	0.56
243_L	247_P	0.846	0.56
772_I	785_Q	0.845	0.56
421_V	714_F	0.844	0.56
258_P	276_T	0.843	0.56
717_Q	720_D	0.842	0.56
249_A	274_F	0.840	0.56
656_N	676_I	0.837	0.55
711_I	714_F	0.837	0.55
124_D	134_L	0.834	0.55
584_V	590_F	0.834	0.55
189_V	194_I	0.833	0.55
442_G	673_R	0.833	0.55
768_I	869_T	0.832	0.55
763_L	771_G	0.830	0.55
555_D	564_Y	0.829	0.55
650_D	653_D	0.829	0.55
423_F	569_R	0.829	0.55
786_V	789_A	0.828	0.55
785_Q	868_K	0.827	0.55
587_W	680_K	0.825	0.54
813_K	816_P	0.824	0.54
683_R	707_D	0.824	0.54
285_L	313_L	0.824	0.54
128_S	132_E	0.823	0.54
305_D	472_G	0.823	0.54
491_L	543_L	0.822	0.54
653_D	867_D	0.822	0.54
294_D	720_D	0.822	0.54
618_E	646_A	0.822	0.54
578_M	584_V	0.819	0.54
482_V	880_A	0.818	0.54
447_M	593_Y	0.817	0.54
249_A	253_A	0.817	0.54
491_L	540_V	0.814	0.53
111_E	114_L	0.811	0.53
171_I	727_R	0.809	0.53
231_S	287_Y	0.809	0.53
335_V	338_S	0.807	0.53
454_F	459_L	0.806	0.53
337_T	340_W	0.803	0.52
119_I	122_T	0.803	0.52
404_N	408_V	0.801	0.52
875_E	879_E	0.800	0.52
317_D	624_A	0.800	0.52
584_V	592_L	0.798	0.52
591_R	718_R	0.798	0.52
687_Q	710_D	0.797	0.52
112_D	479_I	0.797	0.52
607_E	611_F	0.796	0.52
654_H	658_A	0.793	0.51
301_F	350_V	0.793	0.51
353_L	415_D	0.792	0.51
770_G	808_R	0.791	0.51
505_S	508_T	0.790	0.51
211_E	410_L	0.790	0.51
575_K	628_T	0.788	0.51
211_E	404_N	0.788	0.51
210_I	410_L	0.786	0.51
840_R	846_I	0.784	0.51
517_G	522_T	0.784	0.51
807_K	843_P	0.783	0.51
501_T	585_F	0.779	0.50
77_P	101_Y	0.778	0.50
749_V	888_V	0.778	0.50
120_T	133_A	0.778	0.50
765_D	846_I	0.776	0.50
470_F	586_G	0.776	0.50
212_V	308_Y	0.774	0.50
212_V	227_V	0.774	0.50
686_F	880_A	0.773	0.50
583_G	628_T	0.773	0.50
77_P	168_D	0.772	0.50
528_F	693_R	0.770	0.49
302_D	350_V	0.770	0.49
209_D	370_L	0.770	0.49
725_T	869_T	0.769	0.49
709_V	734_D	0.768	0.49
724_I	870_L	0.768	0.49
515_F	527_H	0.767	0.49
139_G	142_P	0.766	0.49
770_G	785_Q	0.765	0.49
101_Y	156_E	0.765	0.49
335_V	341_G	0.765	0.49
145_V	149_R	0.764	0.49
142_P	148_I	0.764	0.49
297_T	763_L	0.764	0.49
492_K	675_Q	0.764	0.49
695_A	733_I	0.763	0.49
205_V	297_T	0.763	0.49
76_R	140_R	0.762	0.49
796_L	801_D	0.760	0.48
448_Y	473_G	0.760	0.48
283_A	287_Y	0.759	0.48
205_V	421_V	0.758	0.48
347_G	493_S	0.758	0.48
348_R	432_G	0.757	0.48
370_L	403_Y	0.757	0.48
90_A	294_D	0.757	0.48
371_D	375_E	0.756	0.48
184_D	195_A	0.755	0.48
598_S	774_K	0.755	0.48
79_L	162_P	0.752	0.48
184_D	290_D	0.751	0.48
587_W	696_G	0.751	0.48
85_T	89_E	0.750	0.48
723_P	726_K	0.749	0.47
104_A	113_D	0.748	0.47
249_A	809_L	0.747	0.47
209_D	602_T	0.746	0.47
81_V	281_H	0.746	0.47
692_K	718_R	0.746	0.47
470_F	595_R	0.745	0.47
636_G	695_A	0.745	0.47
306_A	803_G	0.742	0.47
861_D	873_P	0.742	0.47
555_D	568_D	0.741	0.47
753_I	757_Q	0.740	0.47
356_A	421_V	0.740	0.47
328_R	333_S	0.739	0.47
783_T	790_K	0.739	0.47
549_E	553_R	0.737	0.46
212_V	273_V	0.736	0.46
103_Y	280_M	0.736	0.46
300_N	472_G	0.736	0.46
526_V	596_A	0.735	0.46
167_I	174_G	0.734	0.46
505_S	529_R	0.733	0.46
791_Y	841_R	0.732	0.46
489_L	651_I	0.732	0.46
521_R	527_H	0.732	0.46
83_G	173_D	0.732	0.46
768_I	876_R	0.732	0.46
567_Y	608_V	0.730	0.46
118_V	125_G	0.730	0.46
472_G	627_D	0.730	0.46
476_F	717_Q	0.728	0.46
134_L	458_V	0.728	0.46
232_H	408_V	0.727	0.45
347_G	718_R	0.727	0.45
297_T	415_D	0.725	0.45
81_V	85_T	0.725	0.45
116_D	226_V	0.723	0.45
141_T	651_I	0.721	0.45
570_Q	578_M	0.721	0.45
472_G	692_K	0.721	0.45
473_G	492_K	0.720	0.45
752_V	761_A	0.718	0.45
608_V	659_Y	0.717	0.45
751_G	754_E	0.716	0.44
764_D	847_C	0.715	0.44
370_L	475_V	0.715	0.44
726_K	730_K	0.714	0.44
727_R	731_E	0.714	0.44
430_L	574_V	0.713	0.44
556_D	560_D	0.713	0.44
299_W	776_L	0.713	0.44
469_E	588_D	0.712	0.44
687_Q	719_S	0.711	0.44
378_L	677_E	0.710	0.44
714_F	719_S	0.710	0.44
696_G	715_E	0.710	0.44
792_A	796_L	0.710	0.44
93_V	97_G	0.710	0.44
413_E	676_I	0.709	0.44
478_P	606_R	0.708	0.44
869_T	872_G	0.708	0.44
371_D	384_R	0.707	0.44
774_K	810_Y	0.706	0.44
585_F	725_T	0.706	0.44
693_R	718_R	0.705	0.43
628_T	713_G	0.705	0.43
304_F	403_Y	0.705	0.43
297_T	499_M	0.705	0.43
329_L	484_E	0.703	0.43
113_D	116_D	0.703	0.43
640_T	644_A	0.702	0.43
280_M	740_G	0.702	0.43
630_S	633_L	0.701	0.43
248_D	254_P	0.699	0.43
784_A	788_G	0.699	0.43
392_L	396_D	0.698	0.43
189_V	195_A	0.696	0.43
107_A	200_A	0.696	0.43
571_Q	606_R	0.696	0.43
352_D	580_S	0.695	0.43
255_T	276_T	0.695	0.43
131_G	456_N	0.694	0.42
81_V	644_A	0.694	0.42
787_R	790_K	0.694	0.42
270_D	309_L	0.694	0.42
682_Y	725_T	0.694	0.42
225_P	655_I	0.693	0.42
616_A	631_V	0.692	0.42
696_G	710_D	0.692	0.42
209_D	472_G	0.691	0.42
444_A	501_T	0.690	0.42
487_S	633_L	0.690	0.42
506_P	729_Q	0.689	0.42
507_E	590_F	0.689	0.42
150_D	316_L	0.688	0.42
206_N	284_F	0.688	0.42
285_L	321_D	0.688	0.42
371_D	382_K	0.687	0.42
517_G	523_P	0.687	0.42
884_S	887_E	0.686	0.42
650_D	657_A	0.685	0.42
157_A	461_S	0.685	0.42
368_Y	720_D	0.684	0.42
456_N	500_V	0.684	0.42
543_L	786_V	0.683	0.42
407_D	677_E	0.682	0.41
550_K	570_Q	0.682	0.41
108_T	111_E	0.682	0.41
654_H	761_A	0.681	0.41
553_R	557_H	0.679	0.41
583_G	713_G	0.678	0.41
505_S	810_Y	0.676	0.41
466_D	588_D	0.675	0.41
132_E	811_L	0.675	0.41
552_A	762_D	0.674	0.41
426_E	555_D	0.672	0.41
258_P	269_I	0.672	0.41
587_W	590_F	0.672	0.41
400_L	489_L	0.671	0.40
575_K	713_G	0.671	0.40
183_D	256_A	0.670	0.40
641_K	683_R	0.670	0.40
470_F	598_S	0.669	0.40
544_L	659_Y	0.669	0.40
547_R	606_R	0.668	0.40
461_S	591_R	0.667	0.40
452_K	726_K	0.666	0.40
458_V	870_L	0.665	0.40
793_N	806_P	0.664	0.40
767_G	809_L	0.664	0.40
365_L	590_F	0.663	0.40
838_E	845_V	0.660	0.39
77_P	126_Y	0.660	0.39
305_D	602_T	0.659	0.39
576_V	601_V	0.659	0.39
93_V	179_A	0.659	0.39
110_S	113_D	0.659	0.39
547_R	583_G	0.659	0.39
115_T	193_E	0.659	0.39
516_D	521_R	0.658	0.39
396_D	399_R	0.657	0.39
304_F	374_G	0.656	0.39
723_P	763_L	0.655	0.39
586_G	626_G	0.655	0.39
516_D	522_T	0.654	0.39
170_D	454_F	0.654	0.39
211_E	602_T	0.654	0.39
714_F	729_Q	0.652	0.39
204_R	235_Y	0.651	0.39
414_I	470_F	0.651	0.39
746_E	882_D	0.650	0.39
324_L	395_D	0.649	0.39
557_H	564_Y	0.649	0.39
473_G	602_T	0.648	0.38
205_V	751_G	0.647	0.38
535_I	703_G	0.647	0.38
492_K	591_R	0.647	0.38
353_L	505_S	0.647	0.38
843_P	854_I	0.645	0.38
583_G	627_D	0.645	0.38
651_I	676_I	0.644	0.38
543_L	861_D	0.644	0.38
716_Y	873_P	0.643	0.38
584_V	715_E	0.642	0.38
772_I	788_G	0.642	0.38
841_R	844_D	0.642	0.38
206_N	678_F	0.641	0.38
510_V	527_H	0.641	0.38
300_N	410_L	0.641	0.38
355_Y	360_T	0.640	0.38
711_I	733_I	0.640	0.38
695_A	724_I	0.640	0.38
794_L	802_R	0.640	0.38
178_P	702_E	0.639	0.38
221_D	224_E	0.639	0.38
575_K	627_D	0.639	0.38
271_V	622_E	0.638	0.38
166_L	877_I	0.637	0.38
541_D	649_F	0.637	0.38
581_L	736_V	0.637	0.38
99_R	394_E	0.637	0.38
812_A	858_F	0.637	0.38
160_L	167_I	0.637	0.38
444_A	500_V	0.637	0.38
329_L	333_S	0.635	0.37
547_R	575_K	0.635	0.37
625_Y	628_T	0.634	0.37
77_P	156_E	0.634	0.37
751_G	760_D	0.633	0.37
365_L	373_V	0.633	0.37
472_G	691_K	0.633	0.37
444_A	673_R	0.633	0.37
697_H	707_D	0.632	0.37
147_N	860_V	0.632	0.37
693_R	766_I	0.632	0.37
519_T	527_H	0.632	0.37
256_A	521_R	0.632	0.37
351_F	356_A	0.631	0.37
300_N	382_K	0.630	0.37
695_A	736_V	0.629	0.37
525_G	607_E	0.629	0.37
582_Y	605_N	0.628	0.37
552_A	557_H	0.628	0.37
87_D	112_D	0.628	0.37
84_R	89_E	0.628	0.37
584_V	598_S	0.627	0.37
739_E	742_V	0.627	0.37
348_R	876_R	0.626	0.37
494_L	497_M	0.626	0.37
734_D	751_G	0.626	0.37
102_F	465_Q	0.625	0.36
489_L	659_Y	0.625	0.36
230_T	802_R	0.624	0.36
78_V	81_V	0.624	0.36
442_G	590_F	0.623	0.36
493_S	590_F	0.622	0.36
475_V	602_T	0.622	0.36
292_N	347_G	0.622	0.36
472_G	677_E	0.621	0.36
229_L	539_M	0.621	0.36
648_S	678_F	0.620	0.36
516_D	545_T	0.620	0.36
514_E	518_D	0.619	0.36
423_F	714_F	0.617	0.36
613_E	756_F	0.617	0.36
370_L	602_T	0.617	0.36
314_D	514_E	0.616	0.36
130_R	275_D	0.616	0.36
491_L	594_D	0.615	0.36
455_G	604_T	0.613	0.35
323_D	331_R	0.613	0.35
746_E	888_V	0.613	0.35
291_T	417_K	0.612	0.35
771_G	801_D	0.612	0.35
232_H	884_S	0.612	0.35
585_F	600_G	0.612	0.35
352_D	407_D	0.612	0.35
557_H	563_D	0.612	0.35
249_A	254_P	0.611	0.35
541_D	709_V	0.611	0.35
313_L	766_I	0.611	0.35
378_L	540_V	0.610	0.35
78_V	142_P	0.610	0.35
404_N	407_D	0.610	0.35
348_R	451_H	0.609	0.35
586_G	785_Q	0.609	0.35
472_G	586_G	0.608	0.35
154_H	288_I	0.608	0.35
768_I	864_K	0.607	0.35
111_E	642_A	0.607	0.35
234_S	617_E	0.606	0.35
628_T	692_K	0.606	0.35
471_E	773_G	0.606	0.35
324_L	568_D	0.606	0.35
209_D	373_V	0.605	0.35
373_V	741_D	0.605	0.35
281_H	385_Y	0.605	0.35
537_R	578_M	0.605	0.35
791_Y	842_D	0.604	0.35
723_P	765_D	0.604	0.35
368_Y	494_L	0.604	0.35
816_P	837_R	0.604	0.35
281_H	642_A	0.604	0.35
164_R	389_I	0.604	0.35
506_P	585_F	0.603	0.35
478_P	494_L	0.603	0.35
870_L	874_I	0.603	0.35
483_R	505_S	0.603	0.35
388_D	392_L	0.602	0.35
618_E	860_V	0.601	0.34
275_D	643_E	0.601	0.34
225_P	499_M	0.601	0.34
163_N	447_M	0.600	0.34
717_Q	721_I	0.599	0.34
189_V	192_D	0.599	0.34
116_D	296_L	0.599	0.34
489_L	644_A	0.598	0.34
752_V	755_E	0.598	0.34
352_D	370_L	0.597	0.34
387_G	845_V	0.596	0.34
491_L	865_M	0.596	0.34
287_Y	552_A	0.595	0.34
732_V	806_P	0.595	0.34
587_W	684_R	0.595	0.34
673_R	805_K	0.595	0.34
441_P	590_F	0.595	0.34
272_R	642_A	0.595	0.34
559_P	564_Y	0.595	0.34
616_A	687_Q	0.594	0.34
476_F	776_L	0.594	0.34
758_E	764_D	0.594	0.34
389_I	400_L	0.593	0.34
278_E	747_E	0.593	0.34
546_E	555_D	0.593	0.34
122_T	127_E	0.593	0.34
269_I	405_L	0.592	0.34
229_L	251_V	0.592	0.34
427_A	767_G	0.591	0.34
688_A	719_S	0.591	0.34
437_D	457_F	0.591	0.34
102_F	734_D	0.590	0.34
432_G	591_R	0.590	0.34
103_Y	334_E	0.590	0.34
520_Y	524_T	0.590	0.34
145_V	150_D	0.590	0.34
472_G	580_S	0.589	0.33
627_D	713_G	0.589	0.33
226_V	312_R	0.589	0.33
136_K	454_F	0.589	0.33
497_M	574_V	0.588	0.33
494_L	625_Y	0.587	0.33
875_E	884_S	0.587	0.33
744_A	867_D	0.586	0.33
158_D	164_R	0.586	0.33
414_I	572_A	0.584	0.33
258_P	754_E	0.584	0.33
190_H	193_E	0.582	0.33
258_P	265_D	0.582	0.33
606_R	627_D	0.582	0.33
163_N	174_G	0.582	0.33
556_D	877_I	0.582	0.33
514_E	517_G	0.582	0.33
309_L	652_E	0.581	0.33
756_F	866_L	0.581	0.33
583_G	692_K	0.580	0.33
360_T	720_D	0.580	0.33
224_E	308_Y	0.580	0.33
298_G	347_G	0.579	0.33
81_V	250_T	0.579	0.33
716_Y	729_Q	0.579	0.33
523_P	528_F	0.579	0.33
356_A	420_I	0.578	0.33
519_T	522_T	0.578	0.33
339_G	345_V	0.578	0.33
490_D	495_Y	0.578	0.33
238_E	242_W	0.577	0.33
685_F	696_G	0.577	0.33
504_A	573_A	0.577	0.33
210_I	305_D	0.576	0.32
113_D	754_E	0.576	0.32
781_T	867_D	0.575	0.32
300_N	403_Y	0.575	0.32
365_L	368_Y	0.573	0.32
487_S	600_G	0.573	0.32
243_L	257_V	0.573	0.32
574_V	655_I	0.572	0.32
161_F	499_M	0.572	0.32
373_V	677_E	0.572	0.32
578_M	581_L	0.572	0.32
813_K	817_D	0.572	0.32
295_V	349_V	0.571	0.32
316_L	345_V	0.571	0.32
385_Y	388_D	0.571	0.32
114_L	171_I	0.571	0.32
756_F	847_C	0.571	0.32
575_K	692_K	0.571	0.32
632_M	768_I	0.570	0.32
528_F	679_E	0.570	0.32
384_R	677_E	0.570	0.32
391_D	646_A	0.570	0.32
598_S	726_K	0.570	0.32
226_V	231_S	0.569	0.32
446_D	680_K	0.566	0.32
372_A	607_E	0.566	0.32
883_L	886_D	0.565	0.32
348_R	715_E	0.565	0.32
481_G	586_G	0.564	0.31
437_D	443_D	0.564	0.31
476_F	586_G	0.563	0.31
111_E	197_C	0.563	0.31
208_F	296_L	0.563	0.31
112_D	115_T	0.561	0.31
587_W	710_D	0.561	0.31
92_H	96_H	0.561	0.31
551_K	555_D	0.560	0.31
548_E	577_I	0.560	0.31
352_D	602_T	0.558	0.31
368_Y	805_K	0.558	0.31
192_D	251_V	0.557	0.31
638_D	646_A	0.557	0.31
200_A	425_D	0.557	0.31
423_F	729_Q	0.556	0.31
586_G	772_I	0.556	0.31
207_T	297_T	0.556	0.31
133_A	777_D	0.556	0.31
625_Y	632_M	0.556	0.31
515_F	523_P	0.555	0.31
633_L	649_F	0.555	0.31
469_E	486_V	0.554	0.31
492_K	578_M	0.554	0.31
679_E	753_I	0.553	0.31
646_A	761_A	0.553	0.31
368_Y	572_A	0.553	0.31
577_I	884_S	0.552	0.31
370_L	382_K	0.552	0.31
150_D	296_L	0.552	0.31
598_S	712_T	0.552	0.31
389_I	568_D	0.552	0.31
498_S	505_S	0.551	0.30
130_R	145_V	0.551	0.30
370_L	431_V	0.551	0.30
359_R	684_R	0.551	0.30
430_L	468_E	0.551	0.30
319_R	642_A	0.551	0.30
438_A	866_L	0.550	0.30
360_T	471_E	0.550	0.30
248_D	251_V	0.550	0.30
811_L	860_V	0.550	0.30
594_D	710_D	0.549	0.30
215_R	220_E	0.548	0.30
808_R	865_M	0.548	0.30
449_V	573_A	0.548	0.30
509_K	594_D	0.548	0.30
334_E	340_W	0.547	0.30
282_D	884_S	0.547	0.30
777_D	780_E	0.547	0.30
490_D	694_Y	0.547	0.30
426_E	682_Y	0.547	0.30
504_A	576_V	0.546	0.30
78_V	161_F	0.546	0.30
627_D	718_R	0.546	0.30
95_V	103_Y	0.546	0.30
448_Y	721_I	0.546	0.30
553_R	652_E	0.546	0.30
542_E	549_E	0.545	0.30
338_S	342_G	0.545	0.30
806_P	877_I	0.545	0.30
210_I	281_H	0.545	0.30
371_D	383_E	0.543	0.30
103_Y	119_I	0.543	0.30
417_K	881_L	0.543	0.30
75_E	456_N	0.543	0.30
95_V	870_L	0.542	0.30
176_R	422_A	0.541	0.30
295_V	775_R	0.541	0.30
625_Y	633_L	0.541	0.30
618_E	751_G	0.541	0.30
139_G	146_G	0.541	0.30
618_E	642_A	0.540	0.30
568_D	572_A	0.539	0.30
579_N	583_G	0.539	0.30
599_A	604_T	0.539	0.30
209_D	352_D	0.539	0.30
517_G	530_K	0.538	0.29
348_R	695_A	0.538	0.29
444_A	587_W	0.537	0.29
772_I	789_A	0.536	0.29
704_K	707_D	0.536	0.29
728_V	874_I	0.536	0.29
508_T	606_R	0.535	0.29
290_D	657_A	0.534	0.29
124_D	129_I	0.533	0.29
481_G	785_Q	0.532	0.29
575_K	629_D	0.532	0.29
101_Y	137_I	0.531	0.29
137_I	156_E	0.531	0.29
195_A	456_N	0.531	0.29
557_H	561_S	0.530	0.29
103_Y	111_E	0.530	0.29
126_Y	368_Y	0.529	0.29
79_L	452_K	0.529	0.29
504_A	601_V	0.529	0.29
616_A	800_F	0.529	0.29
674_F	806_P	0.529	0.29
313_L	841_R	0.529	0.29
250_T	259_G	0.528	0.29
358_Q	733_I	0.528	0.29
300_N	602_T	0.527	0.29
371_D	374_G	0.527	0.29
208_F	420_I	0.526	0.29
681_L	687_Q	0.526	0.29
210_I	304_F	0.525	0.29
856_D	859_V	0.525	0.29
465_Q	469_E	0.525	0.29
305_D	352_D	0.525	0.29
478_P	503_N	0.525	0.29
304_F	472_G	0.525	0.29
750_H	757_Q	0.524	0.28
118_V	165_L	0.523	0.28
109_L	113_D	0.523	0.28
270_D	517_G	0.523	0.28
711_I	717_Q	0.523	0.28
441_P	719_S	0.523	0.28
296_L	353_L	0.522	0.28
583_G	629_D	0.522	0.28
619_F	653_D	0.522	0.28
743_D	746_E	0.521	0.28
638_D	653_D	0.521	0.28
305_D	410_L	0.521	0.28
692_K	713_G	0.521	0.28
112_D	116_D	0.521	0.28
298_G	305_D	0.521	0.28
610_D	684_R	0.519	0.28
197_C	309_L	0.519	0.28
585_F	590_F	0.519	0.28
382_K	404_N	0.519	0.28
103_Y	458_V	0.518	0.28
501_T	506_P	0.518	0.28
136_K	161_F	0.516	0.28
712_T	865_M	0.516	0.28
478_P	544_L	0.516	0.28
98_F	164_R	0.516	0.28
284_F	402_E	0.516	0.28
226_V	311_D	0.515	0.28
688_A	773_G	0.515	0.28
215_R	308_Y	0.515	0.28
74_R	316_L	0.514	0.28
119_I	145_V	0.513	0.28
95_V	102_F	0.513	0.28
226_V	747_E	0.512	0.28
593_Y	805_K	0.512	0.28
221_D	601_V	0.512	0.28
287_Y	291_T	0.511	0.27
211_E	307_P	0.509	0.27
837_R	845_V	0.509	0.27
164_R	212_V	0.509	0.27
146_G	151_A	0.509	0.27
268_D	373_V	0.509	0.27
446_D	656_N	0.508	0.27
721_I	869_T	0.507	0.27
112_D	178_P	0.507	0.27
171_I	554_R	0.507	0.27
110_S	114_L	0.506	0.27
621_Y	651_I	0.506	0.27
431_V	543_L	0.506	0.27
478_P	508_T	0.506	0.27
84_R	88_D	0.505	0.27
184_D	191_H	0.505	0.27
134_L	163_N	0.505	0.27
505_S	606_R	0.504	0.27
85_T	870_L	0.504	0.27
148_I	151_A	0.504	0.27
506_P	592_L	0.503	0.27
483_R	536_I	0.503	0.27
442_G	593_Y	0.502	0.27
580_S	677_E	0.501	0.27
685_F	773_G	0.501	0.27
745_V	749_V	0.501	0.27
159_I	648_S	0.501	0.27
523_P	603_S	0.501	0.27
110_S	117_D	0.500	0.27
494_L	808_R	0.500	0.27
581_L	594_D	0.500	0.27
178_P	276_T	0.500	0.27
444_A	447_M	0.500	0.27

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3iayA	1	0.8746	100	0.223	Contact Map
4qclA	1	0.8668	100	0.258	Contact Map
4fvmA	1	0.8324	100	0.274	Contact Map
1qhtA	1	0.7514	100	0.278	Contact Map
2gv9A	1	0.9279	100	0.28	Contact Map
4m8oA	1	0.9212	100	0.298	Contact Map
3k59A	1	0.828	100	0.309	Contact Map
1s5jA	1	0.7303	100	0.336	Contact Map
3qexA	1	0.8491	100	0.346	Contact Map
2py5A	2	0.5006	100	0.704	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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