Q9HRT3 - HALSA - GREMLIN Contacts

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Q9HRT3 - Succinoglycan biosynthesis transport protein

UniProt:	Q9HRT3	Sequences: MGDSTDDHEATAPGETVSEAERDALVTISHGAVVTSGGVSAQRALVAVVEFALARGLGPVAYGVYALAWRIAQLLSRLVTFGSVPTLQRYLPAADARRRSRVTGLAYVTTAGVGLLITAGVWLAAPRLNAATVDHPSFPAAMRLLGVVVVLVGLVMVYAATFRADGSARGEVLFNKLLRPAVRLVGALTALALGYSVVGVAGAYAASMLVLVVLGFPLTARVTGVTPTLRGLRRDARRFYDHAAPVAMSSFGKVFQNRADILLVGALLTAVAAGVYNVVLVLVSIAWIPLLSFNQLLPPVASRLHAAGDIDTLNAVYSSVTRLIVTTVVPILAVELVFGRDLLALFGPTYTRGYGPLAVYLAGVFVGSAVGATGWLLMMTDHQYARMALDWLLAVLNVALTYVFVVEFKLVGAALGTSLAIAVQNALQVLLLRRFEGLWPFDATFLRPLAAGAVMAAAMLGVRSLLVDSSLAIAAGVLVGLPSYLGALSVLGVDPRDRLVVRELATRYRNTIADAVRR	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	518 (463)
Sequences:	17135 (14713)
Seq/√Len:	683.8

ECOLI - WZXC MURJ RFBX WZXE YGHQ
BACSU - EPSK YABM TUAB SP5B YTGP YKVU
HALSA - Q9HRT3 Q9HQQ5 Q9HSW2 Q9HRF2
SULSO - Q7LXE2 Q97XG2 Q97XT3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
309_D	312_T	4.798	1.00
237_R	241_D	3.453	1.00
167_S	170_G	3.155	1.00
124_A	127_R	3.151	1.00
66_A	277_N	3.011	1.00
95_D	98_R	2.990	1.00
382_H	385_A	2.948	1.00
354_Y	358_A	2.929	1.00
443_A	447_R	2.915	1.00
166_G	303_R	2.714	1.00
336_L	358_A	2.698	1.00
382_H	435_F	2.679	1.00
384_Y	388_A	2.602	1.00
275_V	352_R	2.344	1.00
91_L	164_A	2.336	1.00
339_G	354_Y	2.246	1.00
260_D	276_Y	2.245	1.00
359_V	411_V	2.232	1.00
122_W	143_R	2.219	1.00
393_L	424_Q	2.216	1.00
444_T	447_R	2.179	1.00
366_V	422_A	2.117	1.00
340_R	344_A	2.113	1.00
458_A	483_S	2.112	1.00
260_D	401_T	2.087	1.00
339_G	358_A	2.076	1.00
400_L	416_G	2.064	1.00
248_M	387_M	2.063	1.00
264_V	268_L	2.058	1.00
304_L	312_T	2.054	1.00
269_T	272_A	2.024	1.00
196_S	199_G	2.024	1.00
34_V	169_R	2.012	1.00
303_R	307_A	2.003	1.00
356_P	410_L	1.993	1.00
139_P	143_R	1.986	1.00
315_A	319_S	1.981	1.00
359_V	418_S	1.980	1.00
90_Y	242_H	1.978	1.00
408_F	415_L	1.946	1.00
58_G	61_A	1.945	1.00
233_R	237_R	1.932	1.00
101_R	232_L	1.917	1.00
405_V	413_A	1.906	1.00
334_V	338_F	1.904	1.00
338_F	341_D	1.902	1.00
389_L	427_L	1.902	1.00
310_I	314_N	1.872	1.00
263_L	405_V	1.834	1.00
121_V	146_G	1.824	1.00
268_L	272_A	1.822	1.00
89_R	93_A	1.799	1.00
98_R	101_R	1.797	1.00
481_L	485_L	1.778	1.00
263_L	401_T	1.741	1.00
328_V	368_S	1.733	1.00
260_D	417_T	1.724	1.00
333_A	456_A	1.715	1.00
455_M	480_G	1.712	1.00
26_V	30_H	1.706	1.00
455_M	459_M	1.703	1.00
312_T	315_A	1.694	1.00
55_R	347_G	1.688	1.00
409_K	412_G	1.677	1.00
396_L	423_V	1.674	1.00
125_A	143_R	1.672	1.00
67_L	265_G	1.665	1.00
348_P	351_T	1.665	1.00
334_V	477_V	1.654	1.00
126_P	139_P	1.653	1.00
232_L	235_D	1.645	1.00
100_S	104_G	1.631	1.00
268_L	410_L	1.628	1.00
305_H	380_T	1.613	1.00
317_Y	376_L	1.612	1.00
412_G	416_G	1.607	1.00
404_F	416_G	1.596	1.00
355_G	411_V	1.588	1.00
167_S	222_V	1.581	1.00
341_D	344_A	1.577	1.00
252_G	391_W	1.575	1.00
54_A	278_V	1.572	1.00
161_T	165_D	1.562	1.00
404_F	408_F	1.557	1.00
335_E	361_L	1.557	1.00
459_M	480_G	1.546	1.00
426_A	430_L	1.546	1.00
166_G	300_V	1.535	1.00
264_V	413_A	1.527	1.00
329_V	452_G	1.527	1.00
359_V	415_L	1.522	1.00
332_L	365_F	1.520	1.00
343_L	353_G	1.518	1.00
326_T	488_L	1.518	1.00
401_T	405_V	1.516	1.00
65_Y	69_W	1.498	1.00
340_R	358_A	1.496	1.00
340_R	354_Y	1.494	1.00
301_A	313_L	1.490	1.00
366_V	425_N	1.487	1.00
343_L	357_L	1.484	1.00
359_V	414_A	1.481	1.00
356_P	414_A	1.479	1.00
68_A	145_L	1.478	1.00
283_V	360_Y	1.476	1.00
456_A	460_L	1.469	1.00
169_R	173_L	1.459	1.00
399_A	403_V	1.443	1.00
263_L	402_Y	1.439	1.00
338_F	342_L	1.437	1.00
314_N	318_S	1.433	1.00
403_V	406_V	1.431	1.00
355_G	358_A	1.430	1.00
87_L	106_A	1.425	1.00
416_G	420_A	1.420	1.00
183_R	207_S	1.413	1.00
313_L	376_L	1.403	1.00
451_A	487_A	1.400	1.00
430_L	434_R	1.398	1.00
363_G	418_S	1.391	1.00
272_A	410_L	1.390	1.00
93_A	381_D	1.389	1.00
264_V	273_A	1.386	1.00
388_A	392_L	1.376	1.00
454_V	487_A	1.370	1.00
279_V	356_P	1.369	1.00
186_G	203_A	1.366	1.00
199_G	203_A	1.352	1.00
259_A	398_V	1.339	1.00
195_Y	199_G	1.335	1.00
103_T	161_T	1.333	1.00
304_L	316_V	1.326	1.00
245_P	387_M	1.325	1.00
182_V	210_V	1.325	1.00
41_A	177_L	1.325	1.00
397_N	401_T	1.324	1.00
311_D	315_A	1.317	1.00
40_S	44_A	1.310	1.00
50_E	281_V	1.308	1.00
312_T	316_V	1.305	1.00
279_V	353_G	1.293	1.00
451_A	455_M	1.293	1.00
174_F	214_L	1.291	1.00
334_V	455_M	1.270	1.00
325_V	329_V	1.268	1.00
297_L	320_V	1.259	1.00
47_A	51_F	1.254	1.00
51_F	55_R	1.252	1.00
343_L	354_Y	1.251	1.00
141_A	201_A	1.250	1.00
461_G	465_L	1.248	1.00
263_L	267_L	1.246	1.00
389_L	431_L	1.237	1.00
404_F	407_E	1.230	1.00
66_A	274_G	1.223	1.00
397_N	417_T	1.219	1.00
362_A	418_S	1.218	1.00
59_P	275_V	1.217	1.00
150_V	153_G	1.213	1.00
352_R	355_G	1.212	1.00
59_P	349_T	1.204	1.00
461_G	464_S	1.200	1.00
484_Y	488_L	1.197	1.00
49_V	184_L	1.191	1.00
275_V	353_G	1.190	1.00
403_V	407_E	1.190	1.00
42_Q	180_P	1.189	1.00
264_V	276_Y	1.179	1.00
347_G	350_Y	1.175	1.00
174_F	215_G	1.174	1.00
310_I	380_T	1.174	1.00
389_L	428_Q	1.170	1.00
411_V	414_A	1.169	1.00
485_L	489_S	1.164	1.00
86_T	242_H	1.163	1.00
258_R	261_I	1.160	1.00
65_Y	200_V	1.159	1.00
38_G	172_V	1.156	1.00
44_A	48_V	1.155	1.00
318_S	322_R	1.154	1.00
106_A	239_F	1.143	1.00
401_T	417_T	1.139	1.00
408_F	412_G	1.136	1.00
244_A	248_M	1.130	1.00
126_P	143_R	1.130	1.00
50_E	346_F	1.125	1.00
305_H	313_L	1.123	1.00
332_L	336_L	1.123	1.00
301_A	379_M	1.123	1.00
112_G	116_L	1.113	1.00
317_Y	373_T	1.113	1.00
341_D	463_R	1.112	1.00
151_L	209_L	1.110	1.00
245_P	384_Y	1.109	1.00
158_Y	216_F	1.104	1.00
213_V	217_P	1.104	1.00
363_G	414_A	1.102	1.00
67_L	273_A	1.102	1.00
62_Y	66_A	1.101	1.00
376_L	432_L	1.101	1.00
105_L	236_A	1.099	1.00
118_T	122_W	1.097	1.00
127_R	130_A	1.096	1.00
298_P	302_S	1.095	1.00
109_T	236_A	1.094	1.00
59_P	274_G	1.092	1.00
249_S	386_R	1.083	1.00
452_G	456_A	1.073	1.00
90_Y	93_A	1.073	1.00
185_V	189_T	1.072	1.00
151_L	212_V	1.072	1.00
252_G	387_M	1.072	1.00
274_G	277_N	1.071	1.00
460_L	464_S	1.069	1.00
93_A	238_R	1.067	1.00
123_L	126_P	1.065	1.00
35_T	296_L	1.065	1.00
61_A	64_V	1.063	1.00
391_W	395_V	1.062	1.00
92_P	164_A	1.059	1.00
373_T	428_Q	1.058	1.00
356_P	411_V	1.055	1.00
335_E	357_L	1.055	1.00
336_L	339_G	1.054	1.00
397_N	420_A	1.053	1.00
147_V	205_A	1.053	1.00
252_G	394_A	1.051	1.00
101_R	105_L	1.049	1.00
189_T	193_L	1.048	1.00
396_L	400_L	1.046	1.00
125_A	139_P	1.041	1.00
168_A	296_L	1.038	1.00
256_Q	397_N	1.038	1.00
32_A	296_L	1.038	1.00
388_A	391_W	1.037	1.00
260_D	397_N	1.036	1.00
448_P	452_G	1.036	1.00
27_T	30_H	1.033	1.00
401_T	404_F	1.031	1.00
188_L	192_A	1.031	1.00
373_T	429_V	1.030	1.00
91_L	99_R	1.028	1.00
118_T	121_V	1.027	1.00
255_F	394_A	1.026	1.00
202_G	206_A	1.023	1.00
88_Q	160_A	1.022	1.00
238_R	381_D	1.020	1.00
86_T	243_A	1.015	1.00
264_V	410_L	1.014	1.00
395_V	399_A	1.013	1.00
385_A	431_L	1.008	1.00
126_P	130_A	1.002	1.00
80_T	84_V	1.001	1.00
457_A	461_G	1.000	1.00
73_Q	77_R	1.000	1.00
407_E	411_V	0.999	1.00
56_G	191_L	0.997	1.00
108_V	112_G	0.997	1.00
170_G	218_L	0.993	1.00
186_G	190_A	0.993	1.00
122_W	126_P	0.993	1.00
351_T	354_Y	0.991	1.00
477_V	481_L	0.990	1.00
147_V	150_V	0.990	1.00
52_A	56_G	0.989	1.00
242_H	383_Q	0.988	1.00
474_A	478_L	0.988	1.00
190_A	195_Y	0.986	1.00
271_V	275_V	0.984	1.00
267_L	405_V	0.983	1.00
32_A	293_F	0.981	1.00
363_G	366_V	0.981	1.00
203_A	207_S	0.981	1.00
279_V	360_Y	0.980	1.00
430_L	433_R	0.980	1.00
162_F	219_T	0.979	1.00
86_T	239_F	0.978	1.00
216_F	220_A	0.974	1.00
45_L	184_L	0.973	1.00
427_L	431_L	0.968	1.00
54_A	346_F	0.966	1.00
338_F	476_G	0.966	1.00
369_A	425_N	0.961	1.00
358_A	362_A	0.955	1.00
439_W	442_D	0.953	1.00
311_D	314_N	0.952	1.00
31_G	166_G	0.951	1.00
427_L	430_L	0.944	1.00
35_T	172_V	0.939	1.00
300_V	304_L	0.937	1.00
406_V	413_A	0.937	1.00
186_G	206_A	0.936	1.00
415_L	418_S	0.934	1.00
83_S	106_A	0.934	1.00
377_L	431_L	0.932	1.00
187_A	203_A	0.931	1.00
91_L	165_D	0.930	1.00
217_P	221_R	0.929	1.00
64_V	270_A	0.929	1.00
87_L	91_L	0.928	1.00
463_R	476_G	0.928	1.00
300_V	303_R	0.928	1.00
207_S	211_L	0.928	1.00
400_L	404_F	0.925	1.00
304_L	309_D	0.925	1.00
235_D	238_R	0.922	1.00
330_P	484_Y	0.921	1.00
269_T	273_A	0.919	1.00
53_L	200_V	0.918	1.00
418_S	421_I	0.916	1.00
98_R	235_D	0.915	1.00
120_G	124_A	0.914	1.00
231_G	236_A	0.913	1.00
143_R	147_V	0.911	1.00
39_V	43_R	0.910	1.00
198_V	201_A	0.910	1.00
144_L	205_A	0.907	1.00
472_A	476_G	0.905	1.00
234_R	237_R	0.904	1.00
137_S	140_A	0.904	1.00
97_R	101_R	0.903	1.00
240_Y	244_A	0.903	1.00
123_L	127_R	0.902	1.00
99_R	165_D	0.897	1.00
82_G	243_A	0.894	1.00
276_Y	360_Y	0.892	1.00
415_L	419_L	0.891	1.00
341_D	476_G	0.886	1.00
118_T	150_V	0.886	1.00
460_L	463_R	0.885	1.00
378_M	386_R	0.884	1.00
140_A	198_V	0.884	1.00
240_Y	243_A	0.882	1.00
33_V	37_G	0.878	1.00
214_L	218_L	0.877	1.00
360_Y	414_A	0.874	1.00
423_V	427_L	0.874	1.00
402_Y	406_V	0.874	1.00
452_G	455_M	0.874	1.00
89_R	381_D	0.873	1.00
477_V	480_G	0.872	1.00
112_G	115_L	0.871	1.00
273_A	277_N	0.870	1.00
400_L	419_L	0.864	1.00
274_G	278_V	0.863	1.00
58_G	350_Y	0.860	1.00
131_A	135_H	0.860	1.00
313_L	380_T	0.858	1.00
202_G	205_A	0.855	1.00
333_A	452_G	0.854	1.00
324_I	368_S	0.849	1.00
146_G	150_V	0.848	1.00
29_S	33_V	0.847	1.00
336_L	340_R	0.846	1.00
36_S	292_S	0.846	1.00
58_G	349_T	0.846	1.00
68_A	141_A	0.846	1.00
102_V	106_A	0.846	1.00
339_G	357_L	0.844	1.00
116_L	120_G	0.844	1.00
183_R	187_A	0.843	1.00
136_P	140_A	0.842	1.00
470_S	477_V	0.840	1.00
330_P	333_A	0.839	1.00
125_A	146_G	0.839	1.00
148_V	208_M	0.838	1.00
400_L	403_V	0.836	1.00
65_Y	197_V	0.829	1.00
336_L	362_A	0.829	1.00
151_L	205_A	0.829	1.00
204_Y	208_M	0.827	1.00
45_L	49_V	0.825	1.00
140_A	143_R	0.824	1.00
241_D	244_A	0.823	1.00
353_G	356_P	0.822	1.00
115_L	119_A	0.819	1.00
283_V	364_V	0.816	1.00
333_A	337_V	0.815	1.00
261_I	273_A	0.812	1.00
57_L	61_A	0.811	1.00
60_V	270_A	0.810	1.00
386_R	390_D	0.809	1.00
30_H	169_R	0.807	1.00
377_L	386_R	0.804	1.00
322_R	326_T	0.802	1.00
96_A	100_S	0.801	1.00
63_G	274_G	0.801	1.00
62_Y	278_V	0.800	1.00
70_R	261_I	0.799	1.00
279_V	357_L	0.799	1.00
246_V	383_Q	0.798	1.00
363_G	417_T	0.798	1.00
32_A	36_S	0.795	1.00
336_L	361_L	0.794	1.00
104_G	108_V	0.794	1.00
469_S	472_A	0.794	1.00
319_S	322_R	0.792	1.00
280_L	284_S	0.792	1.00
464_S	467_V	0.788	1.00
252_G	390_D	0.787	1.00
155_V	212_V	0.787	1.00
387_M	391_W	0.787	1.00
296_L	299_P	0.784	1.00
107_Y	158_Y	0.784	1.00
51_F	54_A	0.783	1.00
398_V	402_Y	0.780	1.00
446_L	450_A	0.778	1.00
34_V	38_G	0.777	1.00
457_A	460_L	0.776	1.00
53_L	187_A	0.773	1.00
278_V	350_Y	0.773	1.00
290_L	294_N	0.771	1.00
86_T	90_Y	0.770	1.00
462_V	479_V	0.768	1.00
31_G	296_L	0.767	1.00
265_G	273_A	0.767	1.00
205_A	208_M	0.765	1.00
448_P	451_A	0.764	1.00
433_R	436_E	0.762	1.00
362_A	365_F	0.761	1.00
245_P	383_Q	0.758	1.00
51_F	346_F	0.752	1.00
189_T	192_A	0.750	1.00
324_I	372_A	0.749	1.00
114_G	153_G	0.748	1.00
330_P	452_G	0.746	1.00
362_A	366_V	0.746	1.00
277_N	281_V	0.745	1.00
93_A	306_A	0.744	1.00
159_A	163_R	0.743	1.00
251_F	255_F	0.742	1.00
242_H	246_V	0.741	1.00
316_V	320_V	0.739	1.00
218_L	222_V	0.736	1.00
111_A	115_L	0.735	1.00
276_Y	280_L	0.733	1.00
38_G	177_L	0.730	1.00
385_A	388_A	0.729	1.00
127_R	131_A	0.729	1.00
298_P	375_W	0.728	1.00
179_R	183_R	0.727	1.00
186_G	189_T	0.727	1.00
431_L	434_R	0.726	1.00
28_I	32_A	0.724	1.00
119_A	123_L	0.723	1.00
344_A	351_T	0.722	1.00
392_L	395_V	0.722	1.00
281_V	284_S	0.721	1.00
444_T	448_P	0.721	1.00
114_G	118_T	0.721	1.00
69_W	73_Q	0.719	1.00
302_S	306_A	0.719	1.00
401_T	413_A	0.719	1.00
337_V	456_A	0.718	1.00
281_V	285_I	0.717	1.00
183_R	203_A	0.716	1.00
389_L	393_L	0.716	1.00
51_F	345_L	0.715	1.00
105_L	231_G	0.715	1.00
278_V	281_V	0.714	1.00
326_T	330_P	0.712	1.00
373_T	425_N	0.709	1.00
80_T	110_T	0.709	1.00
464_S	468_D	0.709	1.00
304_L	307_A	0.708	1.00
140_A	144_L	0.708	1.00
316_V	319_S	0.707	1.00
143_R	146_G	0.707	1.00
454_V	457_A	0.706	1.00
37_G	41_A	0.706	1.00
96_A	99_R	0.702	1.00
62_Y	274_G	0.701	1.00
50_E	54_A	0.701	1.00
52_A	188_L	0.700	1.00
459_M	476_G	0.700	1.00
254_V	258_R	0.700	1.00
241_D	384_Y	0.699	1.00
411_V	415_L	0.699	1.00
330_P	455_M	0.697	1.00
422_A	426_A	0.697	1.00
278_V	346_F	0.696	1.00
396_L	399_A	0.694	1.00
260_D	280_L	0.694	1.00
486_G	490_V	0.693	1.00
392_L	427_L	0.693	1.00
109_T	113_V	0.684	1.00
298_P	379_M	0.682	1.00
36_S	40_S	0.682	1.00
154_L	212_V	0.679	1.00
455_M	458_A	0.677	1.00
429_V	433_R	0.676	1.00
283_V	286_A	0.676	1.00
108_V	227_P	0.675	1.00
334_V	480_G	0.675	1.00
174_F	211_L	0.673	1.00
65_Y	201_A	0.672	1.00
89_R	383_Q	0.671	1.00
351_T	355_G	0.670	1.00
377_L	432_L	0.670	1.00
349_T	352_R	0.669	1.00
431_L	435_F	0.669	1.00
450_A	453_A	0.668	1.00
179_R	211_L	0.667	1.00
339_G	361_L	0.666	1.00
73_Q	76_S	0.666	1.00
88_Q	164_A	0.666	1.00
445_F	448_P	0.666	1.00
181_A	185_V	0.664	1.00
29_S	32_A	0.664	1.00
462_V	465_L	0.659	1.00
414_A	418_S	0.658	1.00
241_D	245_P	0.657	1.00
88_Q	92_P	0.653	1.00
453_A	457_A	0.651	1.00
144_L	201_A	0.649	1.00
87_L	102_V	0.648	1.00
478_L	481_L	0.648	1.00
487_A	490_V	0.648	1.00
375_W	378_M	0.646	1.00
256_Q	394_A	0.646	1.00
125_A	128_L	0.645	1.00
320_V	372_A	0.643	1.00
246_V	378_M	0.642	1.00
41_A	45_L	0.641	1.00
94_A	98_R	0.641	1.00
363_G	421_I	0.641	1.00
54_A	350_Y	0.640	1.00
375_W	379_M	0.640	1.00
258_R	262_L	0.639	1.00
272_A	275_V	0.638	1.00
373_T	432_L	0.637	1.00
463_R	466_L	0.637	1.00
152_V	208_M	0.630	1.00
142_M	146_G	0.629	1.00
329_V	365_F	0.627	1.00
465_L	468_D	0.627	1.00
35_T	168_A	0.627	1.00
205_A	209_L	0.626	1.00
259_A	263_L	0.624	1.00
90_Y	238_R	0.624	1.00
476_G	480_G	0.619	1.00
293_F	297_L	0.618	1.00
121_V	125_A	0.617	1.00
278_V	353_G	0.616	1.00
249_S	390_D	0.616	1.00
239_F	243_A	0.615	1.00
144_L	202_G	0.615	1.00
383_Q	386_R	0.614	1.00
124_A	128_L	0.614	1.00
134_D	266_A	0.612	1.00
281_V	346_F	0.612	1.00
173_L	178_L	0.612	1.00
163_R	171_E	0.612	1.00
162_F	170_G	0.611	1.00
223_T	227_P	0.610	1.00
462_V	466_L	0.608	1.00
57_L	197_V	0.608	1.00
59_P	271_V	0.605	1.00
160_A	164_A	0.605	1.00
59_P	350_Y	0.605	1.00
470_S	474_A	0.605	1.00
418_S	422_A	0.604	1.00
97_R	100_S	0.604	1.00
105_L	233_R	0.603	1.00
33_V	40_S	0.602	1.00
463_R	472_A	0.602	1.00
215_G	218_L	0.599	1.00
300_V	316_V	0.599	1.00
405_V	412_G	0.599	1.00
179_R	207_S	0.597	1.00
180_P	183_R	0.596	1.00
417_T	420_A	0.596	1.00
258_R	284_S	0.593	1.00
344_A	354_Y	0.593	1.00
234_R	238_R	0.593	1.00
331_I	334_V	0.593	1.00
236_A	240_Y	0.592	1.00
262_L	266_A	0.592	1.00
449_L	452_G	0.592	1.00
455_M	483_S	0.591	1.00
459_M	463_R	0.589	1.00
387_M	390_D	0.586	1.00
182_V	207_S	0.585	1.00
261_I	277_N	0.584	1.00
261_I	280_L	0.582	1.00
125_A	142_M	0.581	1.00
396_L	420_A	0.580	1.00
325_V	365_F	0.580	1.00
478_L	482_P	0.579	1.00
74_L	254_V	0.577	1.00
89_R	379_M	0.576	1.00
61_A	197_V	0.576	1.00
108_V	111_A	0.575	1.00
101_R	104_G	0.574	1.00
184_L	188_L	0.573	1.00
472_A	475_A	0.573	1.00
267_L	402_Y	0.571	1.00
367_G	371_G	0.570	1.00
397_N	400_L	0.570	1.00
366_V	418_S	0.569	1.00
483_S	487_A	0.569	1.00
67_L	70_R	0.569	1.00
178_L	214_L	0.569	1.00
357_L	361_L	0.568	1.00
165_D	222_V	0.567	1.00
291_L	295_Q	0.566	1.00
158_Y	219_T	0.566	1.00
297_L	301_A	0.565	1.00
168_A	172_V	0.564	1.00
26_V	29_S	0.562	1.00
268_L	409_K	0.561	1.00
238_R	242_H	0.561	1.00
451_A	488_L	0.561	1.00
170_G	173_L	0.558	1.00
433_R	437_G	0.557	1.00
322_R	444_T	0.557	1.00
60_V	64_V	0.554	1.00
136_P	139_P	0.553	1.00
198_V	202_G	0.552	1.00
447_R	451_A	0.551	1.00
329_V	333_A	0.551	1.00
313_L	316_V	0.551	1.00
56_G	192_A	0.550	1.00
211_L	215_G	0.550	1.00
46_V	50_E	0.550	1.00
217_P	220_A	0.549	1.00
84_V	160_A	0.549	1.00
424_Q	428_Q	0.548	1.00
35_T	39_V	0.545	1.00
370_V	425_N	0.544	1.00
27_T	166_G	0.544	1.00
108_V	231_G	0.542	1.00
473_I	477_V	0.542	1.00
314_N	442_D	0.541	1.00
335_E	342_L	0.540	1.00
374_G	386_R	0.539	1.00
50_E	62_Y	0.539	1.00
72_A	76_S	0.539	1.00
474_A	477_V	0.538	1.00
99_R	103_T	0.538	1.00
110_T	114_G	0.538	1.00
200_V	204_Y	0.536	1.00
341_D	472_A	0.534	1.00
313_L	317_Y	0.533	1.00
190_A	203_A	0.533	1.00
290_L	371_G	0.533	1.00
53_L	57_L	0.533	1.00
475_A	478_L	0.532	1.00
53_L	62_Y	0.531	1.00
101_R	235_D	0.530	1.00
226_T	230_R	0.530	1.00
267_L	406_V	0.529	1.00
458_A	461_G	0.529	1.00
76_S	80_T	0.528	1.00
117_I	121_V	0.528	1.00
182_V	185_V	0.527	1.00
391_W	394_A	0.527	1.00
116_L	119_A	0.527	1.00
122_W	125_A	0.526	1.00
67_L	261_I	0.526	1.00
71_I	75_L	0.525	1.00
122_W	146_G	0.525	1.00
249_S	387_M	0.525	1.00
393_L	420_A	0.523	1.00
146_G	149_V	0.522	1.00
118_T	146_G	0.522	1.00
64_V	141_A	0.522	1.00
104_G	107_Y	0.522	1.00
70_R	74_L	0.518	0.99
45_L	48_V	0.518	0.99
401_T	416_G	0.517	0.99
158_Y	215_G	0.517	0.99
332_L	361_L	0.515	0.99
159_A	176_K	0.514	0.99
417_T	421_I	0.514	0.99
103_T	158_Y	0.514	0.99
46_V	51_F	0.514	0.99
223_T	226_T	0.514	0.99
338_F	477_V	0.514	0.99
178_L	182_V	0.513	0.99
115_L	150_V	0.511	0.99
60_V	63_G	0.511	0.99
299_P	303_R	0.511	0.99
30_H	34_V	0.510	0.99
211_L	214_L	0.509	0.99
279_V	283_V	0.508	0.99
249_S	253_K	0.508	0.99
41_A	181_A	0.507	0.99
310_I	313_L	0.506	0.99
249_S	252_G	0.505	0.99
385_A	389_L	0.505	0.99
331_I	335_E	0.503	0.99
374_G	378_M	0.503	0.99
386_R	428_Q	0.500	0.99

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4lz6A	1	0.8282	100	0.436	Contact Map
3w4tA	1	0.8205	100	0.445	Contact Map
4humA	1	0.8378	100	0.454	Contact Map
3mktA	1	0.8301	100	0.468	Contact Map
4j05A	3	0.7181	91.1	0.927	Contact Map
1pw4A	1	0.7761	90.9	0.927	Contact Map
3o7qA	1	0.7162	88.9	0.93	Contact Map
3wdoA	1	0.7683	86.7	0.932	Contact Map
4zw9A	1	0.8147	63.4	0.945	Contact Map
4pypA	1	0.7683	63.4	0.945	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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