Q9HRN6 - HALSA - GREMLIN Contacts

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Q9HRN6 - Htr16 transducer

UniProt:	Q9HRN6	Sequences: MYTDDGTPSVAYASPVPEEDALLIAVVRTSERAQRFTSAINGTKTTAVGDTTGDVLFDRNESAFLTQYQSIGGSGVIETIESQDRGTVVTEDTIIAFAAVQDDATNWVVVKETPKSDALAIANNVQTNIWVLLGLTLVGLVGFVAVVRAGLIGSLREITTQTAAIADGNLDQEIQDNGRIDEIGRVRSGFRDIKSYLQTVEGQAIALSQQDFDNDVLDDEVPGTLGESLTAMQTDLETFIEDLTDAREEAERSQRDAEQSREEAQALADSLERQAERFSTQMQQAADGDLTQRLDTDVDRESLAQIATAFNDMLVQLEALVDRIQATANAVDDRTHAMSASTDEIEQSSMSVAKSIEQISAGAENQNEKLTAAAGEMTDLSATVEEIASSSNNVAQQAEDAAAMGQDGQAAATDAIAEMDAIESKATQTVEEMQSLQEEVGRISDIVTMIDDIASQTDMLAINASIEAENASTSGDGFAVVADEVKSLAEDTATATDEVESLIAEVEASTSALAEDMYEMRDRVGDGQDTITDTAALLEDIVDRVEDANAGIQSINDATEDQAASVQEATRMVEEVASVSDQTAGEASNVSAAAEEQTSAIQEISQSAQSLQTQATELLDRAEQFDTS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	628 (510)
Sequences:	1272 (1127)
Seq/√Len:	49.9

ECOLI - AER
BACSU - MCPC TLPB TLPA MCPA MCPB YVAQ YOAH TLPC
HALSA - Q9HRN6 Q9HR88 HTR4 Q9HRA1 HTR2 Q9HP10 COST Q9HS86 Q9HPQ5 Q9HQX8 HTR1 HTR7 Q9HPA2 HTR9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
179_R	184_G	6.136	1.00
164_A	169_N	4.676	1.00
284_Q	289_D	4.469	1.00
162_T	186_V	3.161	1.00
229_L	233_Q	3.044	1.00
368_E	375_G	2.919	1.00
154_S	182_E	2.903	1.00
181_D	184_G	2.793	1.00
293_R	314_L	2.669	1.00
110_V	114_P	2.590	1.00
218_D	221_V	2.537	1.00
162_T	190_F	2.536	1.00
455_S	466_I	2.526	1.00
422_I	527_G	2.517	1.00
165_I	193_I	2.430	1.00
463_N	481_V	2.426	1.00
387_I	559_T	2.396	1.00
158_I	162_T	2.393	1.00
148_R	152_I	2.393	1.00
421_A	523_R	2.386	1.00
588_S	592_A	2.379	1.00
225_L	231_A	2.372	1.00
57_F	65_L	2.296	1.00
108_V	112_E	2.296	1.00
93_T	114_P	2.295	1.00
412_A	535_A	2.290	1.00
162_T	166_A	2.208	1.00
93_T	96_A	2.169	1.00
217_L	220_E	2.135	1.00
79_T	83_Q	2.100	1.00
260_S	265_Q	2.080	1.00
452_D	538_L	2.058	1.00
414_D	533_D	2.053	1.00
227_E	237_E	2.043	1.00
105_T	112_E	2.040	1.00
293_R	318_E	2.029	1.00
229_L	237_E	1.953	0.99
162_T	165_I	1.931	0.99
134_G	138_V	1.921	0.99
193_I	197_L	1.919	0.99
214_N	221_V	1.916	0.99
240_I	243_L	1.907	0.99
77_I	86_G	1.887	0.99
255_R	265_Q	1.885	0.99
105_T	114_P	1.879	0.99
253_S	256_D	1.872	0.99
405_G	409_Q	1.855	0.99
162_T	193_I	1.855	0.99
77_I	80_I	1.847	0.99
104_A	107_W	1.847	0.99
107_W	114_P	1.826	0.99
55_V	60_N	1.823	0.99
84_D	87_T	1.813	0.99
446_I	503_I	1.799	0.99
111_K	114_P	1.789	0.99
225_L	237_E	1.787	0.99
112_E	118_A	1.760	0.99
78_E	81_E	1.754	0.99
57_F	61_E	1.749	0.99
158_I	190_F	1.748	0.99
253_S	257_A	1.741	0.99
230_T	233_Q	1.737	0.99
215_D	219_D	1.736	0.99
233_Q	237_E	1.736	0.99
416_I	535_A	1.733	0.99
203_Q	206_A	1.713	0.99
148_R	151_L	1.694	0.98
250_A	253_S	1.664	0.98
74_S	77_I	1.662	0.98
92_D	96_A	1.661	0.98
228_S	232_M	1.657	0.98
293_R	315_V	1.655	0.98
363_A	587_A	1.649	0.98
99_A	107_W	1.648	0.98
274_Q	278_F	1.635	0.98
79_T	87_T	1.630	0.98
214_N	227_E	1.626	0.98
233_Q	244_T	1.624	0.98
371_T	581_D	1.621	0.98
80_I	84_D	1.612	0.98
495_A	538_L	1.604	0.98
236_L	243_L	1.601	0.98
223_G	231_A	1.595	0.98
170_L	197_L	1.595	0.98
81_E	86_G	1.577	0.97
83_Q	86_G	1.572	0.97
459_M	538_L	1.571	0.97
458_D	481_V	1.570	0.97
359_I	367_N	1.569	0.97
314_L	318_E	1.564	0.97
217_L	221_V	1.543	0.97
225_L	233_Q	1.540	0.97
55_V	68_Y	1.539	0.97
111_K	118_A	1.534	0.97
226_G	233_Q	1.528	0.97
357_E	361_A	1.518	0.97
221_V	229_L	1.507	0.97
75_G	80_I	1.506	0.97
55_V	58_D	1.497	0.96
592_A	595_E	1.495	0.96
254_Q	258_E	1.494	0.96
191_R	194_K	1.490	0.96
93_T	100_V	1.489	0.96
487_S	490_E	1.486	0.96
274_Q	303_L	1.484	0.96
78_E	82_S	1.483	0.96
94_I	97_F	1.483	0.96
248_E	252_R	1.478	0.96
76_V	81_E	1.474	0.96
61_E	69_Q	1.471	0.96
93_T	107_W	1.470	0.96
253_S	261_R	1.467	0.96
381_S	570_T	1.462	0.96
101_Q	107_W	1.461	0.96
154_S	184_G	1.460	0.96
214_N	237_E	1.459	0.96
58_D	67_Q	1.453	0.96
547_D	550_A	1.452	0.96
257_A	261_R	1.450	0.96
99_A	114_P	1.447	0.96
451_D	455_S	1.446	0.96
476_D	483_D	1.443	0.96
224_T	229_L	1.440	0.96
257_A	260_S	1.439	0.96
245_D	248_E	1.437	0.96
226_G	231_A	1.432	0.95
114_P	117_D	1.431	0.95
288_G	311_N	1.421	0.95
94_I	99_A	1.417	0.95
77_I	81_E	1.408	0.95
133_L	137_L	1.384	0.95
404_M	534_T	1.376	0.94
158_I	161_Q	1.372	0.94
65_L	68_Y	1.370	0.94
96_A	99_A	1.370	0.94
165_I	194_K	1.369	0.94
493_A	587_A	1.368	0.94
393_N	554_S	1.360	0.94
226_G	229_L	1.359	0.94
538_L	562_Q	1.356	0.94
219_D	229_L	1.354	0.94
538_L	555_I	1.353	0.94
304_A	308_T	1.347	0.94
219_D	224_T	1.344	0.94
289_D	311_N	1.337	0.93
348_S	534_T	1.326	0.93
255_R	260_S	1.316	0.93
475_G	479_A	1.307	0.93
261_R	265_Q	1.303	0.93
59_R	67_Q	1.301	0.93
105_T	110_V	1.300	0.92
232_M	237_E	1.299	0.92
204_A	211_D	1.298	0.92
466_I	566_V	1.292	0.92
465_S	485_V	1.291	0.92
80_I	87_T	1.291	0.92
224_T	228_S	1.283	0.92
492_T	496_T	1.283	0.92
536_A	539_E	1.279	0.92
118_A	121_I	1.276	0.92
99_A	105_T	1.276	0.92
221_V	233_Q	1.273	0.92
105_T	109_V	1.273	0.92
239_F	242_D	1.270	0.92
105_T	117_D	1.261	0.91
305_Q	309_A	1.247	0.91
240_I	244_T	1.247	0.91
281_Q	310_F	1.242	0.91
529_D	533_D	1.240	0.91
281_Q	294_L	1.232	0.90
358_Q	362_G	1.231	0.90
472_S	475_G	1.229	0.90
228_S	233_Q	1.228	0.90
229_L	240_I	1.224	0.90
83_Q	87_T	1.222	0.90
107_W	110_V	1.221	0.90
202_G	206_A	1.215	0.90
458_D	463_N	1.213	0.90
483_D	487_S	1.213	0.90
294_L	307_A	1.212	0.90
585_G	588_S	1.205	0.89
224_T	231_A	1.201	0.89
218_D	222_P	1.199	0.89
56_L	59_R	1.197	0.89
255_R	258_E	1.194	0.89
112_E	116_S	1.193	0.89
106_N	114_P	1.187	0.89
107_W	125_V	1.179	0.88
355_S	586_E	1.177	0.88
233_Q	239_F	1.175	0.88
93_T	99_A	1.170	0.88
219_D	222_P	1.169	0.88
373_A	572_M	1.165	0.88
565_S	572_M	1.161	0.87
158_I	187_R	1.158	0.87
219_D	233_Q	1.156	0.87
265_Q	269_D	1.154	0.87
248_E	253_S	1.153	0.87
538_L	541_I	1.150	0.87
229_L	243_L	1.148	0.87
107_W	119_L	1.143	0.87
57_F	67_Q	1.134	0.86
82_S	85_R	1.133	0.86
469_E	480_V	1.130	0.86
455_S	490_E	1.121	0.86
96_A	101_Q	1.119	0.85
558_A	562_Q	1.117	0.85
214_N	219_D	1.116	0.85
368_E	581_D	1.110	0.85
108_V	117_D	1.107	0.85
362_G	579_V	1.106	0.85
387_I	466_I	1.105	0.85
237_E	242_D	1.102	0.85
446_I	548_A	1.101	0.84
93_T	108_V	1.101	0.84
438_E	441_G	1.100	0.84
57_F	60_N	1.100	0.84
239_F	243_L	1.099	0.84
58_D	93_T	1.098	0.84
532_T	536_A	1.098	0.84
80_I	85_R	1.097	0.84
67_Q	77_I	1.096	0.84
236_L	242_D	1.095	0.84
58_D	69_Q	1.095	0.84
253_S	258_E	1.093	0.84
223_G	229_L	1.090	0.84
299_D	307_A	1.090	0.84
60_N	63_A	1.088	0.84
401_A	545_V	1.086	0.84
487_S	494_T	1.086	0.84
79_T	85_R	1.085	0.84
83_Q	88_V	1.081	0.83
59_R	117_D	1.080	0.83
81_E	87_T	1.079	0.83
109_V	112_E	1.072	0.83
210_Q	213_D	1.071	0.83
105_T	108_V	1.069	0.83
79_T	86_G	1.068	0.83
220_E	229_L	1.067	0.83
449_M	498_E	1.063	0.82
77_I	84_D	1.062	0.82
159_T	165_I	1.061	0.82
225_L	243_L	1.060	0.82
149_A	153_G	1.058	0.82
462_I	479_A	1.057	0.82
237_E	243_L	1.056	0.82
469_E	485_V	1.054	0.82
585_G	592_A	1.052	0.82
277_R	280_T	1.051	0.82
226_G	230_T	1.049	0.81
59_R	114_P	1.046	0.81
228_S	236_L	1.045	0.81
216_V	233_Q	1.044	0.81
392_N	560_E	1.041	0.81
404_M	540_D	1.038	0.81
534_T	538_L	1.037	0.81
255_R	301_E	1.037	0.81
285_A	313_M	1.035	0.81
131_V	135_L	1.033	0.80
221_V	231_A	1.032	0.80
77_I	85_R	1.030	0.80
77_I	91_E	1.028	0.80
108_V	111_K	1.024	0.80
597_Q	611_L	1.024	0.80
223_G	237_E	1.024	0.80
130_W	134_G	1.021	0.80
375_G	379_D	1.018	0.79
455_S	493_A	1.016	0.79
233_Q	243_L	1.015	0.79
121_I	125_V	1.009	0.79
388_A	391_S	1.009	0.79
61_E	76_V	1.006	0.79
186_V	193_I	1.003	0.78
100_V	105_T	1.002	0.78
229_L	244_T	1.002	0.78
63_A	66_T	0.999	0.78
282_M	309_A	0.995	0.78
267_L	271_L	0.995	0.78
57_F	62_S	0.992	0.78
81_E	84_D	0.992	0.78
267_L	272_E	0.989	0.77
159_T	185_R	0.989	0.77
57_F	69_Q	0.987	0.77
60_N	64_F	0.985	0.77
59_R	113_T	0.983	0.77
500_E	576_V	0.982	0.77
451_D	466_I	0.976	0.77
465_S	487_S	0.975	0.76
228_S	231_A	0.973	0.76
275_A	282_M	0.972	0.76
362_G	586_E	0.971	0.76
76_V	83_Q	0.968	0.76
233_Q	236_L	0.968	0.76
253_S	260_S	0.965	0.76
257_A	265_Q	0.965	0.76
271_L	331_V	0.965	0.76
294_L	304_A	0.964	0.76
363_A	586_E	0.961	0.75
221_V	227_E	0.957	0.75
255_R	263_E	0.957	0.75
56_L	67_Q	0.957	0.75
446_I	502_L	0.955	0.75
466_I	490_E	0.952	0.75
214_N	233_Q	0.952	0.75
76_V	85_R	0.951	0.75
227_E	230_T	0.949	0.74
365_N	575_E	0.949	0.74
204_A	210_Q	0.948	0.74
122_A	129_I	0.947	0.74
226_G	237_E	0.942	0.74
261_R	264_A	0.940	0.74
94_I	98_A	0.939	0.74
228_S	237_E	0.938	0.74
201_E	205_I	0.937	0.74
222_P	225_L	0.935	0.73
465_S	491_D	0.935	0.73
74_S	87_T	0.934	0.73
450_I	484_E	0.931	0.73
475_G	480_V	0.930	0.73
58_D	68_Y	0.929	0.73
481_V	484_E	0.926	0.73
87_T	95_I	0.925	0.73
170_L	198_Q	0.924	0.72
207_L	210_Q	0.924	0.72
90_T	97_F	0.921	0.72
214_N	220_E	0.919	0.72
221_V	232_M	0.917	0.72
56_L	65_L	0.916	0.72
86_G	96_A	0.915	0.72
217_L	222_P	0.914	0.72
324_I	364_E	0.913	0.72
59_R	105_T	0.912	0.72
57_F	77_I	0.912	0.72
111_K	115_K	0.910	0.71
357_E	595_E	0.909	0.71
114_P	119_L	0.908	0.71
59_R	107_W	0.907	0.71
214_N	217_L	0.907	0.71
239_F	244_T	0.907	0.71
221_V	225_L	0.906	0.71
93_T	101_Q	0.906	0.71
93_T	112_E	0.905	0.71
104_A	110_V	0.904	0.71
115_K	119_L	0.902	0.71
58_D	61_E	0.900	0.70
90_T	98_A	0.898	0.70
440_V	611_L	0.898	0.70
474_S	568_E	0.897	0.70
119_L	125_V	0.894	0.70
293_R	311_N	0.893	0.70
87_T	91_E	0.893	0.70
415_A	531_I	0.892	0.70
74_S	86_G	0.892	0.70
220_E	231_A	0.890	0.70
77_I	87_T	0.890	0.70
57_F	112_E	0.889	0.70
65_L	69_Q	0.889	0.70
63_A	73_G	0.887	0.69
223_G	228_S	0.886	0.69
419_M	527_G	0.883	0.69
209_Q	212_F	0.883	0.69
150_G	154_S	0.882	0.69
133_L	144_V	0.882	0.69
107_W	111_K	0.881	0.69
223_G	227_E	0.878	0.69
410_A	414_D	0.875	0.68
208_S	212_F	0.871	0.68
76_V	86_G	0.869	0.68
74_S	85_R	0.868	0.68
214_N	222_P	0.867	0.68
100_V	104_A	0.867	0.68
439_E	611_L	0.865	0.67
151_L	154_S	0.864	0.67
227_E	231_A	0.863	0.67
480_V	484_E	0.863	0.67
78_E	87_T	0.863	0.67
63_A	68_Y	0.862	0.67
55_V	64_F	0.862	0.67
446_I	496_T	0.860	0.67
64_F	68_Y	0.859	0.67
214_N	229_L	0.859	0.67
96_A	104_A	0.859	0.67
185_R	188_S	0.859	0.67
95_I	112_E	0.858	0.67
58_D	62_S	0.858	0.67
60_N	65_L	0.854	0.66
492_T	502_L	0.853	0.66
207_L	211_D	0.852	0.66
105_T	111_K	0.851	0.66
136_T	147_V	0.850	0.66
394_V	524_V	0.848	0.66
58_D	65_L	0.847	0.66
93_T	105_T	0.846	0.66
136_T	144_V	0.845	0.66
453_I	463_N	0.845	0.66
74_S	81_E	0.845	0.66
154_S	183_I	0.844	0.66
61_E	65_L	0.843	0.65
120_A	138_V	0.842	0.65
256_D	259_Q	0.840	0.65
75_G	78_E	0.840	0.65
271_L	310_F	0.839	0.65
69_Q	82_S	0.839	0.65
161_Q	174_I	0.836	0.65
60_N	81_E	0.835	0.65
76_V	92_D	0.835	0.65
88_V	93_T	0.835	0.65
245_D	249_E	0.835	0.65
227_E	235_D	0.833	0.64
286_A	289_D	0.833	0.64
222_P	233_Q	0.832	0.64
216_V	226_G	0.830	0.64
412_A	504_A	0.825	0.64
147_V	150_G	0.825	0.64
73_G	76_V	0.825	0.64
101_Q	105_T	0.825	0.64
394_V	449_M	0.823	0.64
440_V	446_I	0.822	0.63
237_E	240_I	0.822	0.63
216_V	220_E	0.822	0.63
418_E	459_M	0.821	0.63
419_M	422_I	0.821	0.63
58_D	63_A	0.821	0.63
74_S	96_A	0.819	0.63
219_D	226_G	0.818	0.63
55_V	114_P	0.817	0.63
250_A	256_D	0.816	0.63
411_A	530_T	0.816	0.63
418_E	538_L	0.815	0.63
57_F	66_T	0.812	0.62
92_D	95_I	0.812	0.62
271_L	275_A	0.808	0.62
467_E	470_N	0.807	0.62
101_Q	110_V	0.804	0.62
80_I	94_I	0.803	0.62
58_D	77_I	0.803	0.62
56_L	108_V	0.802	0.62
76_V	82_S	0.800	0.61
104_A	111_K	0.800	0.61
60_N	77_I	0.800	0.61
76_V	87_T	0.799	0.61
471_A	475_G	0.797	0.61
412_A	474_S	0.796	0.61
608_A	611_L	0.794	0.61
231_A	235_D	0.791	0.60
235_D	242_D	0.789	0.60
75_G	87_T	0.789	0.60
214_N	218_D	0.788	0.60
59_R	65_L	0.787	0.60
165_I	190_F	0.787	0.60
235_D	239_F	0.787	0.60
61_E	83_Q	0.786	0.60
58_D	76_V	0.786	0.60
462_I	486_K	0.784	0.60
221_V	242_D	0.784	0.60
256_D	261_R	0.782	0.60
92_D	98_A	0.781	0.59
604_I	611_L	0.781	0.59
476_D	486_K	0.780	0.59
92_D	97_F	0.780	0.59
376_E	465_S	0.779	0.59
267_L	274_Q	0.778	0.59
67_Q	82_S	0.776	0.59
229_L	235_D	0.775	0.59
348_S	351_S	0.774	0.59
368_E	372_A	0.760	0.57
57_F	64_F	0.759	0.57
222_P	227_E	0.754	0.57
215_D	221_V	0.753	0.57
274_Q	304_A	0.751	0.56
503_I	527_G	0.751	0.56
229_L	232_M	0.750	0.56
366_Q	579_V	0.749	0.56
247_R	265_Q	0.748	0.56
277_R	294_L	0.748	0.56
204_A	208_S	0.746	0.56
99_A	108_V	0.743	0.56
554_S	557_D	0.742	0.56
235_D	238_T	0.741	0.55
55_V	66_T	0.741	0.55
60_N	69_Q	0.738	0.55
225_L	228_S	0.738	0.55
88_V	92_D	0.736	0.55
376_E	568_E	0.734	0.55
92_D	112_E	0.730	0.54
183_I	190_F	0.729	0.54
597_Q	600_A	0.729	0.54
105_T	116_S	0.728	0.54
65_L	77_I	0.727	0.54
77_I	82_S	0.726	0.54
221_V	226_G	0.724	0.54
88_V	98_A	0.722	0.54
120_A	123_N	0.717	0.53
285_A	314_L	0.717	0.53
58_D	107_W	0.716	0.53
221_V	224_T	0.715	0.53
154_S	159_T	0.715	0.53
67_Q	79_T	0.715	0.53
223_G	243_L	0.714	0.53
466_I	483_D	0.709	0.52
56_L	174_I	0.709	0.52
415_A	576_V	0.709	0.52
126_Q	130_W	0.708	0.52
110_V	113_T	0.707	0.52
61_E	67_Q	0.706	0.52
73_G	77_I	0.704	0.52
265_Q	268_A	0.704	0.52
86_G	107_W	0.704	0.52
85_R	89_V	0.703	0.52
91_E	96_A	0.703	0.52
98_A	119_L	0.702	0.51
122_A	126_Q	0.702	0.51
69_Q	77_I	0.701	0.51
199_T	203_Q	0.701	0.51
469_E	479_A	0.700	0.51
79_T	84_D	0.700	0.51
91_E	109_V	0.699	0.51
88_V	91_E	0.699	0.51
159_T	162_T	0.698	0.51
454_A	479_A	0.696	0.51
110_V	119_L	0.693	0.51
55_V	80_I	0.693	0.51
251_E	254_Q	0.692	0.50
82_S	86_G	0.691	0.50
69_Q	74_S	0.690	0.50
64_F	92_D	0.689	0.50
475_G	481_V	0.687	0.50
114_P	118_A	0.686	0.50
60_N	93_T	0.686	0.50
252_R	256_D	0.685	0.50
109_V	114_P	0.683	0.50
477_G	484_E	0.682	0.49
381_S	385_E	0.680	0.49
56_L	68_Y	0.679	0.49
217_L	229_L	0.673	0.49
162_T	194_K	0.673	0.49
56_L	63_A	0.669	0.48
231_A	242_D	0.668	0.48
576_V	587_A	0.666	0.48
523_R	552_I	0.664	0.48
301_E	307_A	0.663	0.47
452_D	459_M	0.662	0.47
187_R	194_K	0.661	0.47
303_L	310_F	0.661	0.47
84_D	112_E	0.660	0.47
359_I	611_L	0.659	0.47
58_D	105_T	0.659	0.47
236_L	239_F	0.659	0.47
65_L	96_A	0.658	0.47
172_Q	194_K	0.658	0.47
104_A	112_E	0.656	0.47
110_V	123_N	0.655	0.47
78_E	86_G	0.654	0.47
162_T	189_G	0.653	0.46
268_A	274_Q	0.651	0.46
277_R	299_D	0.651	0.46
77_I	93_T	0.649	0.46
58_D	66_T	0.649	0.46
98_A	101_Q	0.648	0.46
364_E	412_A	0.647	0.46
440_V	520_M	0.647	0.46
361_A	365_N	0.646	0.46
158_I	174_I	0.646	0.46
166_A	186_V	0.645	0.46
275_A	301_E	0.644	0.46
226_G	232_M	0.642	0.45
74_S	78_E	0.642	0.45
90_T	111_K	0.642	0.45
414_D	526_D	0.640	0.45
104_A	108_V	0.640	0.45
96_A	105_T	0.640	0.45
452_D	490_E	0.640	0.45
290_L	317_L	0.639	0.45
96_A	106_N	0.639	0.45
228_S	243_L	0.638	0.45
369_K	496_T	0.638	0.45
77_I	88_V	0.637	0.45
91_E	95_I	0.636	0.45
79_T	98_A	0.636	0.45
459_M	469_E	0.635	0.45
483_D	490_E	0.635	0.45
86_G	91_E	0.633	0.44
77_I	95_I	0.632	0.44
74_S	83_Q	0.632	0.44
140_L	144_V	0.632	0.44
415_A	418_E	0.631	0.44
77_I	83_Q	0.631	0.44
75_G	86_G	0.629	0.44
403_A	407_D	0.628	0.44
415_A	538_L	0.626	0.44
84_D	105_T	0.626	0.44
253_S	265_Q	0.625	0.44
75_G	85_R	0.623	0.43
376_E	570_T	0.621	0.43
59_R	73_G	0.621	0.43
62_S	93_T	0.619	0.43
371_T	375_G	0.619	0.43
83_Q	92_D	0.619	0.43
78_E	84_D	0.618	0.43
88_V	107_W	0.618	0.43
81_E	85_R	0.617	0.43
223_G	233_Q	0.617	0.43
383_T	573_V	0.617	0.43
356_I	594_A	0.616	0.43
147_V	154_S	0.614	0.43
492_T	497_D	0.613	0.42
527_G	538_L	0.612	0.42
376_E	386_E	0.611	0.42
100_V	107_W	0.609	0.42
452_D	491_D	0.608	0.42
86_G	101_Q	0.608	0.42
483_D	500_E	0.608	0.42
260_S	264_A	0.606	0.42
304_A	307_A	0.606	0.42
146_V	152_I	0.606	0.42
408_G	538_L	0.606	0.42
55_V	69_Q	0.604	0.42
466_I	586_E	0.604	0.42
86_G	109_V	0.603	0.41
88_V	99_A	0.603	0.41
99_A	109_V	0.603	0.41
236_L	244_T	0.602	0.41
319_A	323_R	0.602	0.41
253_S	274_Q	0.601	0.41
99_A	104_A	0.598	0.41
60_N	76_V	0.598	0.41
238_T	242_D	0.597	0.41
200_V	203_Q	0.597	0.41
215_D	228_S	0.596	0.41
112_E	117_D	0.594	0.41
216_V	219_D	0.593	0.40
451_D	500_E	0.591	0.40
284_Q	292_Q	0.591	0.40
74_S	79_T	0.590	0.40
257_A	263_E	0.590	0.40
77_I	112_E	0.589	0.40
496_T	566_V	0.588	0.40
360_S	447_V	0.588	0.40
76_V	84_D	0.588	0.40
452_D	463_N	0.586	0.40
100_V	106_N	0.584	0.40
93_T	98_A	0.583	0.39
227_E	243_L	0.582	0.39
56_L	66_T	0.582	0.39
97_F	101_Q	0.581	0.39
59_R	76_V	0.580	0.39
486_K	583_T	0.579	0.39
466_I	496_T	0.579	0.39
385_E	567_Q	0.578	0.39
94_I	101_Q	0.577	0.39
57_F	93_T	0.577	0.39
440_V	535_A	0.576	0.39
76_V	91_E	0.575	0.39
104_A	114_P	0.574	0.39
230_T	234_T	0.573	0.38
158_I	186_V	0.573	0.38
216_V	243_L	0.573	0.38
568_E	571_R	0.572	0.38
466_I	577_A	0.569	0.38
88_V	95_I	0.568	0.38
225_L	244_T	0.568	0.38
227_E	233_Q	0.568	0.38
225_L	236_L	0.567	0.38
61_E	64_F	0.567	0.38
61_E	82_S	0.566	0.38
224_T	233_Q	0.565	0.38
402_A	406_Q	0.565	0.38
440_V	524_V	0.564	0.38
408_G	465_S	0.564	0.38
90_T	93_T	0.563	0.38
184_G	187_R	0.562	0.37
91_E	111_K	0.562	0.37
446_I	455_S	0.561	0.37
57_F	110_V	0.561	0.37
597_Q	604_I	0.560	0.37
221_V	236_L	0.560	0.37
380_L	534_T	0.559	0.37
129_I	133_L	0.558	0.37
383_T	493_A	0.557	0.37
98_A	114_P	0.556	0.37
250_A	254_Q	0.555	0.37
82_S	87_T	0.555	0.37
55_V	59_R	0.554	0.37
496_T	502_L	0.554	0.37
387_I	446_I	0.552	0.36
75_G	79_T	0.551	0.36
405_G	542_V	0.551	0.36
581_D	586_E	0.550	0.36
382_A	561_D	0.550	0.36
63_A	69_Q	0.549	0.36
108_V	114_P	0.549	0.36
450_I	480_V	0.547	0.36
317_L	604_I	0.546	0.36
247_R	250_A	0.545	0.36
161_Q	172_Q	0.544	0.36
449_M	503_I	0.543	0.36
455_S	462_I	0.543	0.36
391_S	394_V	0.541	0.35
212_F	215_D	0.537	0.35
104_A	119_L	0.537	0.35
78_E	85_R	0.537	0.35
86_G	97_F	0.536	0.35
89_V	98_A	0.535	0.35
110_V	122_A	0.534	0.35
221_V	237_E	0.534	0.35
101_Q	108_V	0.531	0.35
454_A	462_I	0.530	0.34
455_S	496_T	0.530	0.34
96_A	118_A	0.529	0.34
220_E	224_T	0.529	0.34
231_A	236_L	0.529	0.34
218_D	225_L	0.529	0.34
401_A	548_A	0.528	0.34
59_R	66_T	0.528	0.34
415_A	503_I	0.527	0.34
589_N	592_A	0.527	0.34
56_L	61_E	0.527	0.34
64_F	97_F	0.527	0.34
64_F	67_Q	0.525	0.34
466_I	484_E	0.525	0.34
258_E	261_R	0.524	0.34
268_A	271_L	0.522	0.34
280_T	292_Q	0.522	0.34
89_V	120_A	0.522	0.34
83_Q	91_E	0.522	0.34
214_N	228_S	0.521	0.34
73_G	110_V	0.520	0.33
144_V	147_V	0.520	0.33
398_A	548_A	0.520	0.33
294_L	306_I	0.520	0.33
260_S	301_E	0.519	0.33
218_D	229_L	0.519	0.33
55_V	65_L	0.519	0.33
456_Q	486_K	0.518	0.33
83_Q	95_I	0.517	0.33
290_L	327_T	0.516	0.33
96_A	112_E	0.515	0.33
107_W	140_L	0.514	0.33
84_D	89_V	0.514	0.33
505_E	523_R	0.514	0.33
101_Q	106_N	0.512	0.33
80_I	112_E	0.512	0.33
412_A	528_Q	0.512	0.33
275_A	303_L	0.511	0.33
368_E	371_T	0.510	0.33
247_R	253_S	0.510	0.33
254_Q	257_A	0.510	0.33
174_I	191_R	0.509	0.32
449_M	493_A	0.509	0.32
93_T	97_F	0.509	0.32
154_S	181_D	0.508	0.32
380_L	404_M	0.508	0.32
62_S	67_Q	0.508	0.32
58_D	74_S	0.506	0.32
107_W	112_E	0.505	0.32
597_Q	603_E	0.504	0.32
97_F	119_L	0.504	0.32
221_V	235_D	0.503	0.32
59_R	82_S	0.503	0.32
129_I	158_I	0.502	0.32
59_R	63_A	0.501	0.32
147_V	151_L	0.500	0.32
229_L	236_L	0.500	0.32
201_E	210_Q	0.500	0.32
220_E	226_G	0.500	0.32

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3zx6A	2	0.4841	100	0.536	Contact Map
2ch7A	2	0.492	100	0.604	Contact Map
1qu7A	2	0.3615	100	0.608	Contact Map
3g67A	2	0.3328	100	0.687	Contact Map
4i3mA	2	0.2389	99.9	0.833	Contact Map
4cq4A	4	0.1385	99.7	0.86	Contact Map
3licA	2	0.1831	99.4	0.888	Contact Map
3lifA	1	0.1847	99.4	0.889	Contact Map
3c8cA	2	0.1959	99.4	0.892	Contact Map
3li9A	2	0.1847	99.3	0.894	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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