Q9HRN1 - HALSA - GREMLIN Contacts

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Q9HRN1 - Propionyl-CoA carboxylase homolog

UniProt:	Q9HRN1	Sequences: MIMKVRIGVGATDAEASAVAAALAAHVSDDVAVYLGDADEPAAVHEPEPPADDSADADDLGPTEREEVLREEIADILDGGPEKYKQRLPEQDKLFVRDRLALWFGDDDDGDDDLLFEDGRFAHFDGWHPNSPDVDEADDGTRVPADGLITGAADFDGRDLHFMANDFTVKAGSMAERGVEKFLRMQQRALKTGKPVLYLMDSSGGRIDQQSGFFANREGIGKYYFNHSRLSGRVPQICVLYGPCIAGAAYTPVFADFTIMVEGMSAMAIASPRMVEMVTGEQIEMQDLGGPQVHAEQSGSADLVARDEDHARELVADLVQYLPDNSDEKPPSQPAKPPAKPPKGIDGLIPEAPNRAYDMHDLIGRVVDQDSFFELRPEYGAEILTGYARIDGRTVGIVANQPAQRAGAIFPDAAEKAAEFVWKSDAYNIPLLYLCDTPGFMPGSSVEKDAILEKGKKMIYATSEATVPKQSVVVRKAYGAGIYAMSGPAYDPESTIALPSGEIGIMGPEAAINAVYANKLDAIDDPEERKQREQELREAYREDIDAHRMASETVIDEIVPPSELRTELSNRFSFYEDVEKDRPSKKHGTIL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	591 (499)
Sequences:	4455 (1920)
Seq/√Len:	85.9

BACSU - PCCB YNGE
HALSA - Q9HRN1 Q9HPQ0
SULSO - Q97VY8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
359_M	384_L	4.888	1.00
367_V	388_A	4.811	1.00
284_E	287_D	4.426	1.00
372_F	386_G	4.340	1.00
383_I	417_A	4.234	1.00
82_E	86_Q	4.110	1.00
262_E	306_R	4.060	1.00
104_F	153_A	3.955	1.00
104_F	162_F	3.696	1.00
239_V	315_V	3.647	1.00
366_V	434_L	3.525	1.00
276_E	282_Q	3.387	1.00
187_Q	226_N	3.071	1.00
346_D	562_S	2.953	1.00
396_G	424_S	2.877	1.00
390_I	568_L	2.853	1.00
534_Q	538_E	2.812	1.00
432_L	572_F	2.806	1.00
532_R	535_E	2.765	1.00
359_M	474_V	2.754	1.00
472_V	564_L	2.711	1.00
86_Q	90_E	2.685	1.00
114_L	154_D	2.676	1.00
346_D	560_P	2.565	1.00
435_C	471_S	2.559	1.00
259_I	315_V	2.539	1.00
303_L	375_L	2.485	1.00
295_A	378_E	2.333	1.00
367_V	397_I	2.297	1.00
94_L	102_L	2.233	1.00
291_P	304_V	2.222	1.00
295_A	301_A	2.211	1.00
305_A	314_L	2.168	1.00
470_Q	572_F	2.142	1.00
390_I	569_S	2.139	1.00
283_I	444_S	2.130	1.00
415_E	454_K	2.126	1.00
391_D	569_S	2.124	1.00
96_V	149_I	2.123	1.00
259_I	311_A	2.116	1.00
307_D	310_H	2.112	1.00
388_A	397_I	2.110	1.00
238_C	255_A	2.104	1.00
161_H	194_K	2.102	1.00
563_E	566_T	2.093	1.00
89_P	98_D	2.083	1.00
161_H	185_M	2.066	1.00
432_L	568_L	2.057	1.00
68_V	72_E	2.046	1.00
119_G	184_R	2.021	1.00
85_K	89_P	2.008	1.00
306_R	310_H	2.006	1.00
498_L	564_L	1.988	1.00
539_A	543_D	1.984	1.00
391_D	573_S	1.982	1.00
260_M	265_S	1.972	1.00
342_P	365_R	1.970	1.00
337_P	340_K	1.968	1.00
262_E	292_Q	1.958	1.00
538_E	542_E	1.910	1.00
102_L	309_D	1.906	1.00
362_L	474_V	1.906	1.00
363_I	367_V	1.902	1.00
336_K	371_S	1.882	1.00
395_V	432_L	1.876	1.00
393_R	576_E	1.850	1.00
190_L	230_L	1.841	1.00
73_I	557_E	1.831	1.00
67_E	71_E	1.828	1.00
321_Y	371_S	1.811	1.00
70_R	560_P	1.793	1.00
259_I	314_L	1.784	1.00
115_L	151_G	1.779	1.00
103_W	155_F	1.746	1.00
310_H	314_L	1.746	1.00
102_L	313_E	1.733	1.00
100_L	162_F	1.726	1.00
295_A	304_V	1.724	1.00
102_L	312_R	1.715	1.00
360_H	374_E	1.709	1.00
100_L	104_F	1.709	1.00
532_R	536_L	1.699	1.00
159_D	194_K	1.684	1.00
123_H	146_D	1.683	1.00
533_E	537_R	1.677	1.00
339_A	369_Q	1.675	1.00
417_A	458_M	1.670	1.00
293_V	448_K	1.670	1.00
125_D	176_E	1.662	1.00
73_I	120_R	1.654	1.00
158_R	323_P	1.652	1.00
96_V	164_A	1.650	1.00
470_Q	568_L	1.628	1.00
297_Q	448_K	1.626	1.00
156_D	320_Q	1.622	1.00
530_K	534_Q	1.605	1.00
241_Y	308_E	1.605	1.00
432_L	470_Q	1.593	1.00
434_L	472_V	1.582	1.00
497_A	501_G	1.580	1.00
259_I	318_L	1.554	1.00
259_I	305_A	1.551	1.00
494_S	571_R	1.533	1.00
292_Q	296_E	1.525	1.00
206_R	209_Q	1.508	1.00
425_D	466_T	1.498	0.99
262_E	304_V	1.491	0.99
302_D	376_R	1.491	0.99
317_D	371_S	1.490	0.99
344_G	365_R	1.472	0.99
376_R	385_T	1.456	0.99
237_I	315_V	1.446	0.99
68_V	71_E	1.438	0.99
363_I	434_L	1.425	0.99
146_D	177_R	1.424	0.99
525_D	528_E	1.423	0.99
287_D	444_S	1.421	0.99
444_S	448_K	1.408	0.99
186_Q	196_V	1.404	0.99
69_L	547_H	1.401	0.99
78_D	82_E	1.399	0.99
397_I	432_L	1.396	0.99
199_L	239_V	1.388	0.99
379_Y	412_D	1.387	0.99
531_Q	535_E	1.386	0.99
560_P	563_E	1.383	0.99
104_F	114_L	1.383	0.99
363_I	397_I	1.381	0.99
148_L	182_F	1.366	0.99
472_V	568_L	1.358	0.99
536_L	539_A	1.355	0.99
557_E	567_E	1.345	0.99
163_M	198_Y	1.341	0.99
496_I	567_E	1.339	0.99
122_A	177_R	1.336	0.99
268_A	285_M	1.335	0.99
87_R	90_E	1.320	0.99
425_D	465_A	1.320	0.99
77_L	120_R	1.318	0.99
190_L	229_R	1.311	0.99
528_E	531_Q	1.301	0.99
120_R	557_E	1.298	0.99
199_L	241_Y	1.271	0.98
63_T	67_E	1.270	0.98
241_Y	312_R	1.266	0.98
154_D	573_S	1.263	0.98
540_Y	544_I	1.258	0.98
363_I	386_G	1.257	0.98
72_E	547_H	1.253	0.98
199_L	312_R	1.241	0.98
523_I	532_R	1.236	0.98
367_V	390_I	1.235	0.98
358_D	361_D	1.234	0.98
470_Q	571_R	1.233	0.98
68_V	545_D	1.233	0.98
85_K	95_F	1.231	0.98
477_A	482_I	1.230	0.98
173_S	203_S	1.228	0.98
394_T	429_I	1.228	0.98
74_A	77_L	1.226	0.98
76_I	121_F	1.218	0.98
72_E	75_D	1.216	0.98
536_L	540_Y	1.215	0.98
411_P	449_D	1.209	0.98
186_Q	226_N	1.206	0.98
363_I	372_F	1.200	0.98
80_G	168_T	1.198	0.98
478_Y	502_E	1.195	0.97
222_K	489_A	1.192	0.97
343_K	346_D	1.182	0.97
215_A	552_E	1.182	0.97
526_P	530_K	1.181	0.97
123_H	177_R	1.175	0.97
158_R	324_D	1.173	0.97
70_R	73_I	1.172	0.97
76_I	145_A	1.172	0.97
150_T	185_M	1.171	0.97
81_P	85_K	1.167	0.97
191_K	493_E	1.166	0.97
191_K	580_K	1.160	0.97
303_L	314_L	1.159	0.97
227_H	251_T	1.155	0.97
470_Q	575_Y	1.153	0.97
296_E	378_E	1.149	0.97
511_A	540_Y	1.148	0.97
78_D	85_K	1.146	0.97
305_A	311_A	1.145	0.97
241_Y	264_M	1.136	0.97
83_K	86_Q	1.132	0.96
303_L	373_F	1.128	0.96
508_P	541_R	1.128	0.96
422_W	464_E	1.126	0.96
344_G	347_G	1.126	0.96
153_A	162_F	1.121	0.96
221_G	483_Y	1.116	0.96
440_F	484_A	1.111	0.96
381_A	404_Q	1.102	0.96
502_E	541_R	1.101	0.96
310_H	313_E	1.098	0.96
218_E	489_A	1.097	0.96
513_N	533_E	1.097	0.96
94_L	308_E	1.096	0.96
421_V	465_A	1.095	0.96
305_A	310_H	1.095	0.96
395_V	572_F	1.091	0.96
529_R	533_E	1.086	0.96
73_I	563_E	1.086	0.96
433_Y	462_T	1.082	0.95
126_G	177_R	1.079	0.95
526_P	529_R	1.076	0.95
336_K	369_Q	1.068	0.95
100_L	164_A	1.068	0.95
361_D	364_G	1.066	0.95
154_D	159_D	1.066	0.95
292_Q	378_E	1.065	0.95
304_V	378_E	1.065	0.95
89_P	95_F	1.064	0.95
336_K	339_A	1.064	0.95
496_I	571_R	1.059	0.95
257_F	303_L	1.057	0.95
360_H	384_L	1.056	0.95
512_I	536_L	1.050	0.95
367_V	432_L	1.049	0.95
281_E	444_S	1.047	0.95
308_E	312_R	1.045	0.95
314_L	373_F	1.045	0.95
71_E	75_D	1.045	0.95
71_E	74_A	1.043	0.94
507_G	510_A	1.040	0.94
503_I	549_M	1.039	0.94
182_F	223_Y	1.036	0.94
116_F	570_N	1.036	0.94
161_H	192_T	1.034	0.94
230_L	234_V	1.030	0.94
167_F	243_P	1.028	0.94
535_E	539_A	1.027	0.94
374_E	377_P	1.025	0.94
192_T	493_E	1.017	0.94
388_A	395_V	1.015	0.94
314_L	317_D	1.014	0.94
95_F	98_D	1.012	0.94
156_D	324_D	1.011	0.93
303_L	377_P	1.009	0.93
343_K	562_S	0.999	0.93
155_F	319_V	0.998	0.93
197_L	319_V	0.998	0.93
332_S	393_R	0.997	0.93
519_K	532_R	0.996	0.93
536_L	541_R	0.992	0.93
471_S	495_T	0.990	0.93
388_A	432_L	0.985	0.93
533_E	536_L	0.983	0.93
520_L	529_R	0.981	0.92
257_F	318_L	0.978	0.92
523_I	526_P	0.973	0.92
73_I	77_L	0.968	0.92
227_H	236_Q	0.964	0.92
225_F	229_R	0.963	0.92
87_R	91_Q	0.961	0.92
327_D	579_E	0.961	0.92
78_D	81_P	0.960	0.92
520_L	524_D	0.959	0.92
183_L	226_N	0.957	0.91
88_L	93_K	0.955	0.91
317_D	373_F	0.952	0.91
144_P	169_V	0.952	0.91
119_G	150_T	0.951	0.91
159_D	573_S	0.950	0.91
146_D	206_R	0.948	0.91
509_E	537_R	0.948	0.91
88_L	167_F	0.946	0.91
123_H	142_R	0.946	0.91
202_S	248_A	0.943	0.91
81_P	84_Y	0.943	0.91
520_L	532_R	0.939	0.91
483_Y	489_A	0.936	0.91
159_D	574_F	0.933	0.90
390_I	472_V	0.932	0.90
361_D	365_R	0.931	0.90
311_A	315_V	0.925	0.90
73_I	121_F	0.925	0.90
358_D	401_Q	0.924	0.90
332_S	391_D	0.924	0.90
520_L	523_I	0.922	0.90
390_I	395_V	0.922	0.90
152_A	194_K	0.920	0.90
292_Q	304_V	0.919	0.90
155_F	160_L	0.916	0.90
160_L	197_L	0.913	0.89
333_Q	389_R	0.911	0.89
335_A	391_D	0.910	0.89
400_N	485_M	0.908	0.89
241_Y	261_V	0.908	0.89
345_I	362_L	0.907	0.89
398_V	421_V	0.906	0.89
228_S	254_F	0.905	0.89
497_A	549_M	0.905	0.89
469_K	486_S	0.904	0.89
179_V	219_G	0.897	0.89
158_R	331_P	0.896	0.89
221_G	489_A	0.892	0.88
152_A	161_H	0.890	0.88
348_L	365_R	0.889	0.88
311_A	314_L	0.889	0.88
118_D	150_T	0.886	0.88
488_P	556_D	0.885	0.88
445_S	448_K	0.884	0.88
283_I	287_D	0.884	0.88
434_L	474_V	0.883	0.88
77_L	101_A	0.882	0.88
183_L	187_Q	0.876	0.87
335_A	340_K	0.876	0.87
156_D	316_A	0.875	0.87
337_P	341_P	0.873	0.87
516_Y	533_E	0.872	0.87
561_P	564_L	0.871	0.87
431_L	486_S	0.868	0.87
546_A	549_M	0.865	0.87
340_K	364_G	0.864	0.87
463_S	490_Y	0.862	0.87
431_L	469_K	0.859	0.86
123_H	551_S	0.857	0.86
476_K	502_E	0.857	0.86
239_V	259_I	0.855	0.86
415_E	453_E	0.848	0.86
273_R	517_A	0.847	0.86
324_D	328_E	0.839	0.85
283_I	448_K	0.839	0.85
222_K	226_N	0.837	0.85
411_P	454_K	0.835	0.85
417_A	421_V	0.832	0.85
534_Q	537_R	0.832	0.85
383_I	409_I	0.831	0.85
76_I	550_A	0.831	0.85
504_G	544_I	0.830	0.84
512_I	520_L	0.829	0.84
462_T	486_S	0.829	0.84
375_L	385_T	0.829	0.84
188_R	192_T	0.828	0.84
250_Y	455_G	0.827	0.84
423_K	427_Y	0.826	0.84
96_V	100_L	0.825	0.84
509_E	513_N	0.824	0.84
315_V	318_L	0.824	0.84
352_A	355_R	0.823	0.84
393_R	573_S	0.822	0.84
155_F	312_R	0.822	0.84
431_L	465_A	0.821	0.84
82_E	85_K	0.821	0.84
225_F	463_S	0.820	0.84
239_V	312_R	0.817	0.84
341_P	563_E	0.817	0.84
165_N	178_G	0.817	0.84
432_L	472_V	0.816	0.83
64_E	67_E	0.816	0.83
496_I	557_E	0.816	0.83
421_V	431_L	0.813	0.83
74_A	78_D	0.810	0.83
357_Y	402_P	0.808	0.83
143_V	170_K	0.808	0.83
259_I	303_L	0.805	0.83
449_D	454_K	0.804	0.83
259_I	373_F	0.802	0.82
122_A	553_T	0.802	0.82
527_E	531_Q	0.793	0.82
224_Y	247_G	0.793	0.82
473_V	495_T	0.790	0.81
391_D	566_T	0.790	0.81
519_K	522_A	0.786	0.81
323_P	326_S	0.783	0.81
543_D	548_R	0.782	0.81
372_F	384_L	0.779	0.80
559_V	564_L	0.777	0.80
455_G	505_I	0.776	0.80
409_I	414_A	0.775	0.80
121_F	550_A	0.773	0.80
382_E	410_F	0.773	0.80
98_D	101_A	0.773	0.80
445_S	449_D	0.772	0.80
75_D	142_R	0.770	0.80
177_R	180_E	0.769	0.80
525_D	529_R	0.769	0.80
94_L	309_D	0.765	0.79
118_D	185_M	0.764	0.79
331_P	389_R	0.763	0.79
118_D	188_R	0.762	0.79
538_E	541_R	0.759	0.79
455_G	507_G	0.758	0.79
237_I	318_L	0.757	0.79
398_V	425_D	0.756	0.78
178_G	182_F	0.756	0.78
104_F	160_L	0.755	0.78
563_E	567_E	0.755	0.78
225_F	491_D	0.755	0.78
364_G	371_S	0.754	0.78
509_E	541_R	0.753	0.78
196_V	234_V	0.752	0.78
336_K	340_K	0.750	0.78
379_Y	415_E	0.750	0.78
89_P	96_V	0.744	0.77
341_P	366_V	0.744	0.77
174_M	182_F	0.743	0.77
97_R	117_E	0.742	0.77
516_Y	519_K	0.739	0.77
309_D	313_E	0.739	0.77
249_A	452_L	0.739	0.77
548_R	551_S	0.738	0.77
567_E	570_N	0.734	0.76
152_A	159_D	0.732	0.76
341_P	344_G	0.731	0.76
85_K	88_L	0.729	0.76
539_A	544_I	0.729	0.76
294_H	298_S	0.729	0.76
337_P	566_T	0.727	0.76
175_A	178_G	0.727	0.76
88_L	95_F	0.727	0.76
492_P	495_T	0.725	0.76
494_S	574_F	0.724	0.75
222_K	491_D	0.724	0.75
159_D	577_D	0.721	0.75
250_Y	505_I	0.721	0.75
488_P	495_T	0.721	0.75
190_L	234_V	0.718	0.75
418_A	461_A	0.718	0.75
329_K	393_R	0.717	0.75
238_C	252_P	0.717	0.75
489_A	554_V	0.716	0.75
421_V	462_T	0.715	0.75
104_F	154_D	0.714	0.74
164_A	199_L	0.714	0.74
233_R	326_S	0.713	0.74
66_E	560_P	0.711	0.74
162_F	197_L	0.711	0.74
363_I	399_A	0.710	0.74
364_G	370_D	0.708	0.74
176_E	552_E	0.708	0.74
80_G	84_Y	0.706	0.74
103_W	197_L	0.705	0.73
68_V	547_H	0.705	0.73
264_M	312_R	0.705	0.73
342_P	345_I	0.703	0.73
433_Y	469_K	0.700	0.73
530_K	533_E	0.697	0.73
175_A	206_R	0.697	0.73
152_A	574_F	0.694	0.72
431_L	462_T	0.693	0.72
390_I	470_Q	0.693	0.72
342_P	566_T	0.692	0.72
486_S	492_P	0.692	0.72
201_D	248_A	0.692	0.72
161_H	188_R	0.690	0.72
239_V	311_A	0.689	0.72
541_R	544_I	0.688	0.72
161_H	574_F	0.688	0.72
520_L	526_P	0.688	0.72
156_D	160_L	0.687	0.72
317_D	320_Q	0.687	0.72
385_T	420_F	0.685	0.71
260_M	301_A	0.685	0.71
103_W	312_R	0.685	0.71
545_D	549_M	0.683	0.71
261_V	311_A	0.682	0.71
88_L	91_Q	0.681	0.71
163_M	196_V	0.680	0.71
573_S	576_E	0.679	0.71
193_G	325_N	0.679	0.71
337_P	391_D	0.678	0.71
519_K	523_I	0.676	0.70
293_V	297_Q	0.675	0.70
88_L	168_T	0.674	0.70
320_Q	389_R	0.672	0.70
66_E	346_D	0.672	0.70
201_D	244_C	0.672	0.70
152_A	192_T	0.672	0.70
229_R	466_T	0.672	0.70
78_D	86_Q	0.672	0.70
324_D	331_P	0.669	0.70
537_R	541_R	0.669	0.70
349_I	362_L	0.669	0.70
66_E	69_L	0.669	0.70
382_E	413_A	0.665	0.69
348_L	362_L	0.665	0.69
104_F	155_F	0.664	0.69
523_I	528_E	0.664	0.69
155_F	162_F	0.662	0.69
103_W	162_F	0.662	0.69
264_M	308_E	0.661	0.69
183_L	222_K	0.661	0.69
69_L	73_I	0.661	0.69
205_G	213_F	0.661	0.69
330_P	428_N	0.660	0.69
197_L	237_I	0.660	0.69
101_A	112_D	0.660	0.69
339_A	391_D	0.660	0.69
93_K	264_M	0.659	0.68
389_R	394_T	0.659	0.68
340_K	390_I	0.658	0.68
104_F	197_L	0.658	0.68
360_H	401_Q	0.657	0.68
344_G	362_L	0.657	0.68
498_L	561_P	0.656	0.68
435_C	486_S	0.655	0.68
312_R	316_A	0.655	0.68
65_R	68_V	0.654	0.68
471_S	486_S	0.654	0.68
231_S	426_A	0.653	0.68
473_V	497_A	0.652	0.68
372_F	434_L	0.652	0.68
197_L	315_V	0.652	0.68
262_E	291_P	0.651	0.67
509_E	533_E	0.651	0.67
119_G	122_A	0.651	0.67
67_E	70_R	0.651	0.67
484_A	495_T	0.651	0.67
171_A	203_S	0.650	0.67
335_A	338_P	0.649	0.67
325_N	428_N	0.648	0.67
231_S	457_K	0.647	0.67
384_L	474_V	0.643	0.67
520_L	536_L	0.641	0.66
257_F	423_K	0.640	0.66
116_F	152_A	0.640	0.66
330_P	394_T	0.639	0.66
228_S	463_S	0.639	0.66
387_Y	423_K	0.636	0.66
72_E	545_D	0.635	0.66
93_K	167_F	0.634	0.65
65_R	351_E	0.633	0.65
187_Q	491_D	0.631	0.65
319_V	322_L	0.631	0.65
267_M	452_L	0.630	0.65
319_V	394_T	0.629	0.65
330_P	393_R	0.629	0.65
332_S	394_T	0.628	0.65
118_D	496_I	0.627	0.65
383_I	458_M	0.626	0.64
576_E	580_K	0.626	0.64
525_D	535_E	0.625	0.64
292_Q	306_R	0.624	0.64
349_I	353_P	0.623	0.64
418_A	458_M	0.623	0.64
275_V	513_N	0.622	0.64
193_G	578_V	0.622	0.64
75_D	78_D	0.622	0.64
209_Q	212_G	0.621	0.64
437_T	440_F	0.621	0.64
428_N	580_K	0.620	0.64
577_D	580_K	0.619	0.64
184_R	556_D	0.619	0.64
314_L	318_L	0.618	0.63
451_I	455_G	0.618	0.63
114_L	197_L	0.618	0.63
567_E	571_R	0.618	0.63
202_S	243_P	0.617	0.63
379_Y	454_K	0.617	0.63
348_L	361_D	0.616	0.63
380_G	453_E	0.614	0.63
205_G	505_I	0.614	0.63
298_S	450_A	0.613	0.63
175_A	453_E	0.612	0.63
85_K	168_T	0.611	0.63
378_E	381_A	0.609	0.62
329_K	579_E	0.609	0.62
360_H	377_P	0.608	0.62
275_V	300_S	0.608	0.62
186_Q	230_L	0.608	0.62
193_G	579_E	0.608	0.62
76_I	120_R	0.606	0.62
128_H	142_R	0.605	0.62
83_K	87_R	0.605	0.62
409_I	413_A	0.604	0.62
183_L	186_Q	0.603	0.62
548_R	552_E	0.603	0.62
571_R	575_Y	0.603	0.62
411_P	451_I	0.603	0.62
432_L	575_Y	0.603	0.62
101_A	113_D	0.603	0.62
254_F	460_Y	0.602	0.61
160_L	323_P	0.602	0.61
93_K	201_D	0.601	0.61
339_A	342_P	0.600	0.61
199_L	308_E	0.599	0.61
275_V	288_L	0.599	0.61
165_N	186_Q	0.597	0.61
353_P	502_E	0.596	0.61
70_R	74_A	0.595	0.61
415_E	484_A	0.595	0.61
218_E	483_Y	0.595	0.61
160_L	319_V	0.593	0.60
203_S	271_S	0.593	0.60
188_R	191_K	0.592	0.60
155_F	375_L	0.591	0.60
313_E	316_A	0.591	0.60
187_Q	191_K	0.590	0.60
193_G	233_R	0.590	0.60
240_L	252_P	0.589	0.60
302_D	375_L	0.589	0.60
442_P	480_A	0.589	0.60
517_A	521_D	0.588	0.60
281_E	445_S	0.587	0.60
345_I	349_I	0.587	0.60
275_V	408_A	0.584	0.59
254_F	490_Y	0.584	0.59
100_L	149_I	0.584	0.59
532_R	539_A	0.583	0.59
388_A	572_F	0.582	0.59
566_T	569_S	0.582	0.59
86_Q	89_P	0.581	0.59
397_I	568_L	0.581	0.59
199_L	548_R	0.580	0.59
194_K	574_F	0.579	0.58
203_S	514_A	0.579	0.58
338_P	370_D	0.577	0.58
313_E	317_D	0.576	0.58
159_D	192_T	0.575	0.58
340_K	370_D	0.575	0.58
423_K	429_I	0.574	0.58
180_E	222_K	0.574	0.58
247_G	250_Y	0.573	0.58
341_P	566_T	0.573	0.58
357_Y	425_D	0.573	0.58
79_G	168_T	0.573	0.58
200_M	248_A	0.572	0.58
559_V	567_E	0.572	0.58
575_Y	578_V	0.572	0.58
158_R	193_G	0.571	0.57
126_G	551_S	0.570	0.57
536_L	544_I	0.569	0.57
301_A	304_V	0.567	0.57
229_R	491_D	0.565	0.57
437_T	451_I	0.564	0.57
187_Q	217_R	0.563	0.56
186_Q	198_Y	0.563	0.56
268_A	273_R	0.563	0.56
159_D	570_N	0.563	0.56
470_Q	496_I	0.562	0.56
553_T	556_D	0.562	0.56
149_I	164_A	0.562	0.56
293_V	296_E	0.562	0.56
522_A	525_D	0.561	0.56
572_F	575_Y	0.561	0.56
421_V	433_Y	0.560	0.56
473_V	501_G	0.560	0.56
401_Q	503_I	0.559	0.56
335_A	339_A	0.556	0.55
447_E	450_A	0.555	0.55
156_D	313_E	0.555	0.55
267_M	300_S	0.555	0.55
433_Y	486_S	0.554	0.55
422_W	461_A	0.554	0.55
201_D	243_P	0.552	0.55
390_I	566_T	0.552	0.55
574_F	577_D	0.551	0.55
250_Y	480_A	0.551	0.55
125_D	552_E	0.550	0.55
415_E	457_K	0.550	0.55
81_P	399_A	0.549	0.55
148_L	178_G	0.549	0.55
550_A	558_I	0.546	0.54
454_K	457_K	0.546	0.54
291_P	301_A	0.545	0.54
516_Y	539_A	0.545	0.54
72_E	538_E	0.544	0.54
495_T	555_I	0.543	0.54
364_G	377_P	0.543	0.54
87_R	140_G	0.543	0.54
124_F	127_W	0.542	0.54
73_I	76_I	0.542	0.54
218_E	222_K	0.542	0.54
263_G	286_Q	0.541	0.53
201_D	241_Y	0.541	0.53
321_Y	394_T	0.541	0.53
458_M	485_M	0.541	0.53
79_G	169_V	0.541	0.53
171_A	514_A	0.540	0.53
277_M	513_N	0.539	0.53
257_F	375_L	0.539	0.53
387_Y	427_Y	0.539	0.53
443_G	450_A	0.537	0.53
520_L	533_E	0.536	0.53
390_I	572_F	0.535	0.53
506_M	511_A	0.534	0.53
123_H	126_G	0.533	0.52
362_L	498_L	0.532	0.52
366_V	498_L	0.532	0.52
102_L	316_A	0.530	0.52
222_K	554_V	0.530	0.52
117_E	181_K	0.529	0.52
566_T	570_N	0.529	0.52
266_A	285_M	0.528	0.52
396_G	420_F	0.528	0.52
103_W	199_L	0.526	0.51
216_N	489_A	0.526	0.51
243_P	266_A	0.526	0.51
281_E	290_G	0.526	0.51
179_V	183_L	0.525	0.51
329_K	576_E	0.525	0.51
101_A	524_D	0.524	0.51
114_L	117_E	0.524	0.51
261_V	307_D	0.524	0.51
574_F	578_V	0.524	0.51
350_P	353_P	0.523	0.51
352_A	356_A	0.523	0.51
523_I	529_R	0.522	0.51
221_G	269_I	0.521	0.51
83_K	90_E	0.521	0.51
114_L	570_N	0.521	0.51
193_G	324_D	0.521	0.51
525_D	530_K	0.520	0.51
154_D	570_N	0.519	0.50
118_D	161_H	0.519	0.50
293_V	408_A	0.518	0.50
460_Y	464_E	0.518	0.50
458_M	489_A	0.517	0.50
499_P	561_P	0.516	0.50
80_G	85_K	0.516	0.50
412_D	449_D	0.515	0.50
362_L	365_R	0.515	0.50
434_L	572_F	0.515	0.50
321_Y	373_F	0.515	0.50
67_E	82_E	0.515	0.50
247_G	506_M	0.515	0.50
114_L	151_G	0.514	0.50
478_Y	504_G	0.514	0.50
196_V	230_L	0.513	0.50
224_Y	250_Y	0.513	0.50
231_S	236_Q	0.513	0.50
393_R	572_F	0.512	0.50
146_D	170_K	0.512	0.50
250_Y	271_S	0.512	0.50
318_L	423_K	0.512	0.50
493_E	578_V	0.512	0.50
348_L	355_R	0.512	0.50
491_D	549_M	0.510	0.49
332_S	573_S	0.509	0.49
573_S	577_D	0.509	0.49
121_F	547_H	0.509	0.49
576_E	579_E	0.508	0.49
528_E	535_E	0.507	0.49
174_M	220_I	0.507	0.49
292_Q	295_A	0.507	0.49
419_E	453_E	0.506	0.49
340_K	343_K	0.505	0.49
202_S	280_G	0.503	0.48
85_K	98_D	0.502	0.48
121_F	558_I	0.502	0.48
174_M	178_G	0.500	0.48
90_E	534_Q	0.500	0.48

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3u9rB	5	0.8917	100	0.245	Contact Map
3n6rB	4	0.8511	100	0.245	Contact Map
1vrgA	4	0.868	100	0.25	Contact Map
4rcnA	6	0.8849	100	0.262	Contact Map
1pixA	4	0.9052	100	0.272	Contact Map
2bzrA	4	0.8494	100	0.275	Contact Map
3gf3A	4	0.8934	100	0.275	Contact Map
3iavA	4	0.8714	100	0.288	Contact Map
1on3A	6	0.8765	100	0.306	Contact Map
1x0uA	5	0.8697	100	0.32	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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