Q9HRM0 - HALSA - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

Q9HRM0 - NADH dehydrogenase/oxidoreductase

UniProt:	Q9HRM0	Sequences: MSSDQPRDSITDTSDPLTSTRDARMGDGVDDRFNSRLREAFGSTPFILTKFDKFMNWVRGSSMFMLQFGIACCSIEMMHTYSVKHDLDRFHAGVPRASPRQADVMIVPGTIVSKFAPRMKRVYDQMPEPKFVVNMGNCSTSGGPFQEGYNVVKGAEEVIPVDIHIPGCPPRPEALVYGVAKLQERIANGESSPVTVKPYELEEFGDLERDEIVDKLAADIDEESLVMRYNWADSP	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	235 (191)
Sequences:	363 (106)
Seq/√Len:	7.7

ECOLI - NUOB HYCG HYFI
HALSA - Q9HRM0
SULSO - Q7LXP2 Q97ZA8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
69_G	74_S	3.996	0.97
165_I	178_G	3.650	0.95
70_I	77_M	3.295	0.91
84_K	173_E	3.218	0.90
80_T	176_V	3.189	0.89
118_R	153_K	2.772	0.81
140_T	145_F	2.573	0.76
50_K	53_K	2.454	0.72
46_F	163_I	2.434	0.72
82_S	87_L	2.334	0.68
70_I	137_N	2.298	0.67
56_N	108_P	2.263	0.66
134_N	140_T	2.248	0.65
66_L	102_A	2.239	0.65
122_V	155_A	2.206	0.64
90_F	171_R	2.189	0.63
114_K	126_M	2.076	0.59
113_S	126_M	1.887	0.51
54_F	104_V	1.878	0.51
77_M	137_N	1.877	0.51
106_I	135_M	1.780	0.47
88_D	92_A	1.773	0.47
165_I	175_L	1.764	0.46
104_V	175_L	1.759	0.46
122_V	172_P	1.728	0.45
121_R	124_D	1.661	0.42
98_S	130_K	1.622	0.41
68_F	151_V	1.616	0.40
147_E	172_P	1.602	0.40
88_D	179_V	1.592	0.40
199_Y	207_L	1.591	0.40
74_S	81_Y	1.584	0.39
134_N	137_N	1.576	0.39
177_Y	181_K	1.544	0.38
210_D	213_V	1.541	0.38
114_K	135_M	1.538	0.37
50_K	186_I	1.519	0.37
64_F	149_Y	1.499	0.36
77_M	134_N	1.483	0.35
63_M	186_I	1.479	0.35
81_Y	106_I	1.477	0.35
70_I	140_T	1.464	0.35
26_G	36_R	1.454	0.34
139_S	159_I	1.443	0.34
134_N	145_F	1.435	0.34
56_N	98_S	1.429	0.33
137_N	178_G	1.427	0.33
128_E	186_I	1.410	0.33
94_V	187_A	1.399	0.32
108_P	126_M	1.399	0.32
110_T	174_A	1.390	0.32
107_V	158_V	1.388	0.32
56_N	130_K	1.368	0.31
85_H	173_E	1.359	0.31
77_M	195_T	1.352	0.31
144_P	147_E	1.348	0.31
66_L	130_K	1.346	0.31
180_A	214_D	1.340	0.30
49_T	163_I	1.322	0.30
84_K	120_K	1.319	0.30
206_D	213_V	1.283	0.28
209_R	212_I	1.271	0.28
84_K	185_R	1.267	0.28
42_G	45_P	1.253	0.28
137_N	140_T	1.248	0.27
120_K	124_D	1.246	0.27
68_F	105_M	1.244	0.27
67_Q	74_S	1.241	0.27
118_R	171_R	1.199	0.26
206_D	210_D	1.193	0.26
70_I	134_N	1.189	0.26
141_S	172_P	1.186	0.25
151_V	178_G	1.159	0.25
210_D	214_D	1.157	0.25
149_Y	161_V	1.155	0.24
70_I	195_T	1.154	0.24
131_F	134_N	1.147	0.24
56_N	173_E	1.144	0.24
114_K	152_V	1.138	0.24
141_S	171_R	1.116	0.23
209_R	215_K	1.108	0.23
75_I	130_K	1.103	0.23
98_S	101_Q	1.101	0.23
144_P	153_K	1.086	0.23
77_M	140_T	1.082	0.22
205_G	212_I	1.071	0.22
50_K	199_Y	1.069	0.22
71_A	149_Y	1.068	0.22
158_V	201_L	1.046	0.21
124_D	209_R	1.024	0.21
71_A	151_V	1.017	0.21
71_A	94_V	1.013	0.21
78_M	104_V	1.004	0.20
66_L	98_S	1.003	0.20
205_G	208_E	1.002	0.20
130_K	165_I	0.999	0.20
42_G	46_F	0.993	0.20
82_S	121_R	0.989	0.20
144_P	172_P	0.988	0.20
65_M	155_A	0.986	0.20
52_D	173_E	0.986	0.20
206_D	212_I	0.983	0.20
87_L	121_R	0.966	0.19
141_S	153_K	0.951	0.19
68_F	178_G	0.950	0.19
107_V	139_S	0.938	0.19
147_E	150_N	0.937	0.19
75_I	145_F	0.931	0.18
105_M	108_P	0.928	0.18
147_E	153_K	0.925	0.18
110_T	140_T	0.920	0.18
95_P	175_L	0.919	0.18
85_H	165_I	0.916	0.18
207_L	210_D	0.915	0.18
51_F	191_S	0.913	0.18
180_A	183_Q	0.904	0.18
30_D	37_L	0.902	0.18
148_G	153_K	0.897	0.18
75_I	140_T	0.897	0.18
156_E	164_H	0.896	0.18
207_L	214_D	0.895	0.18
47_I	199_Y	0.894	0.18
120_K	184_E	0.893	0.18
99_P	109_G	0.884	0.17
211_E	214_D	0.876	0.17
66_L	105_M	0.872	0.17
92_A	127_P	0.871	0.17
149_Y	210_D	0.868	0.17
25_M	28_G	0.867	0.17
100_R	109_G	0.865	0.17
155_A	172_P	0.863	0.17
87_L	178_G	0.862	0.17
71_A	118_R	0.857	0.17
65_M	108_P	0.855	0.17
120_K	215_K	0.853	0.17
80_T	87_L	0.852	0.17
165_I	171_R	0.851	0.17
151_V	165_I	0.848	0.17
131_F	139_S	0.846	0.16
197_K	211_E	0.845	0.16
33_F	36_R	0.844	0.16
53_K	187_A	0.844	0.16
147_E	157_E	0.834	0.16
45_P	163_I	0.834	0.16
130_K	178_G	0.833	0.16
65_M	135_M	0.831	0.16
137_N	165_I	0.829	0.16
25_M	29_V	0.826	0.16
209_R	213_V	0.823	0.16
127_P	180_A	0.822	0.16
37_L	83_V	0.818	0.16
123_Y	129_P	0.806	0.16
203_E	207_L	0.806	0.16
126_M	132_V	0.796	0.15
141_S	146_Q	0.792	0.15
41_F	190_E	0.789	0.15
24_R	30_D	0.785	0.15
82_S	155_A	0.784	0.15
63_M	104_V	0.776	0.15
110_T	151_V	0.775	0.15
158_V	183_Q	0.770	0.15
184_E	187_A	0.764	0.15
88_D	141_S	0.762	0.15
206_D	209_R	0.759	0.15
133_V	150_N	0.756	0.15
150_N	195_T	0.755	0.15
141_S	147_E	0.755	0.15
78_M	81_Y	0.754	0.15
61_S	141_S	0.749	0.14
199_Y	209_R	0.749	0.14
84_K	175_L	0.749	0.14
60_G	186_I	0.748	0.14
44_T	149_Y	0.748	0.14
98_S	207_L	0.743	0.14
153_K	158_V	0.742	0.14
48_L	102_A	0.740	0.14
38_R	41_F	0.738	0.14
204_F	213_V	0.734	0.14
94_V	117_P	0.729	0.14
48_L	187_A	0.727	0.14
121_R	180_A	0.724	0.14
39_E	42_G	0.722	0.14
83_V	130_K	0.719	0.14
207_L	213_V	0.714	0.14
101_Q	173_E	0.713	0.14
74_S	78_M	0.712	0.14
120_K	139_S	0.711	0.14
81_Y	92_A	0.710	0.14
111_I	161_V	0.708	0.14
94_V	180_A	0.705	0.14
40_A	46_F	0.701	0.14
144_P	150_N	0.701	0.14
68_F	165_I	0.696	0.13
78_M	95_P	0.692	0.13
107_V	159_I	0.691	0.13
175_L	183_Q	0.687	0.13
71_A	122_V	0.687	0.13
116_A	159_I	0.683	0.13
141_S	144_P	0.680	0.13
122_V	163_I	0.677	0.13
111_I	115_F	0.670	0.13
79_H	171_R	0.658	0.13
45_P	171_R	0.658	0.13
96_R	109_G	0.651	0.13
37_L	116_A	0.645	0.13
52_D	185_R	0.644	0.13
106_I	175_L	0.640	0.12
171_R	188_N	0.635	0.12
69_G	150_N	0.634	0.12
34_N	37_L	0.631	0.12
68_F	183_Q	0.630	0.12
131_F	150_N	0.628	0.12
142_G	154_G	0.627	0.12
43_S	128_E	0.627	0.12
131_F	140_T	0.626	0.12
103_D	136_G	0.624	0.12
85_H	137_N	0.624	0.12
52_D	101_Q	0.624	0.12
117_P	161_V	0.619	0.12
68_F	75_I	0.613	0.12
87_L	186_I	0.602	0.12
128_E	164_H	0.597	0.12
46_F	51_F	0.596	0.12
96_R	100_R	0.595	0.12
199_Y	205_G	0.594	0.12
199_Y	204_F	0.592	0.12
212_I	215_K	0.590	0.12
31_D	34_N	0.590	0.12
102_A	122_V	0.590	0.12
111_I	155_A	0.589	0.12
49_T	113_S	0.586	0.12
138_C	161_V	0.586	0.12
48_L	213_V	0.585	0.12
87_L	92_A	0.583	0.11
45_P	172_P	0.582	0.11
206_D	214_D	0.582	0.11
80_T	197_K	0.580	0.11
117_P	182_L	0.579	0.11
29_V	34_N	0.575	0.11
35_S	40_A	0.574	0.11
198_P	202_E	0.568	0.11
96_R	99_P	0.568	0.11
75_I	134_N	0.567	0.11
119_M	155_A	0.564	0.11
24_R	28_G	0.563	0.11
100_R	103_D	0.560	0.11
36_R	63_M	0.560	0.11
198_P	214_D	0.559	0.11
31_D	111_I	0.559	0.11
44_T	52_D	0.558	0.11
59_R	105_M	0.556	0.11
32_R	38_R	0.555	0.11
91_H	136_G	0.551	0.11
82_S	131_F	0.551	0.11
89_R	109_G	0.549	0.11
199_Y	203_E	0.540	0.11
58_V	61_S	0.537	0.11
36_R	41_F	0.534	0.11
64_F	164_H	0.534	0.11
65_M	156_E	0.533	0.11
207_L	212_I	0.532	0.11
31_D	70_I	0.531	0.11
209_R	214_D	0.528	0.11
41_F	207_L	0.527	0.11
67_Q	81_Y	0.526	0.11
178_G	203_E	0.526	0.11
200_E	209_R	0.526	0.11
99_P	103_D	0.525	0.11
39_E	204_F	0.524	0.11
31_D	77_M	0.522	0.11
61_S	120_K	0.520	0.10
54_F	126_M	0.520	0.10
85_H	203_E	0.518	0.10
25_M	189_G	0.517	0.10
193_P	198_P	0.514	0.10
45_P	79_H	0.509	0.10
63_M	155_A	0.508	0.10
101_Q	127_P	0.506	0.10
91_H	103_D	0.506	0.10
198_P	208_E	0.504	0.10
137_N	195_T	0.503	0.10
140_T	195_T	0.503	0.10
75_I	193_P	0.502	0.10
105_M	159_I	0.501	0.10
81_Y	147_E	0.500	0.10
32_R	37_L	0.500	0.10

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3i9v6	1	0.617	100	0.475	Contact Map
1h2aS	1	0.7021	100	0.65	Contact Map
2wpnA	1	0.7447	100	0.656	Contact Map
3ayxB	2	0.6979	100	0.658	Contact Map
4ue3S	2	0.7106	100	0.667	Contact Map
4uqlA	1	0.7106	100	0.668	Contact Map
1yq9A	2	0.7277	100	0.678	Contact Map
3myrA	3	0.7064	100	0.679	Contact Map
3ze9A	1	0.7021	100	0.68	Contact Map
4u9hS	1	0.7064	100	0.683	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0084 seconds.