Q9HRL9 - HALSA - GREMLIN Contacts

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Q9HRL9 - NADH dehydrogenase/oxidoreductase

UniProt:	Q9HRL9	Sequences: MSTQQEDDTPDVDDAAPATPASGSPAALEALIEDHVLEREDHLNAPGFVIRADAVQDVLSTLKTEAGFDHLSCVTAEEHEDRFESIYHLRKYDDPTQEVSIIVPTSRDNPVSETAEPVFRTADWHEREAYDLVGVEYDDHPNLERILLPDTWQGHPLGLDYNQNKPQIVTFDEHKNPLEGHEQAADDSDTMFLNIGPHHPATHGVLHVETVLDGEQVADVNPDIGYLHRCEEQMAQKGTYRHQIMPYPDRWDYGPGGILNEWAYARTAEDLADIDVPEYAQILRTMGGELCRIACHMLALGTFCLDIYGDFTAIFMYAMRDREVVQNILEDLTGQRMMLNYLRLGGVVWDIPEPRAEFFESVRDFLDELPERLDEYSDLITSNEIFQARTVNTGVLDYETAKDYGVTGPVARGSGVDYDVRRDDPYGYYPELDWDVVTEDGGDNYSRLLVRMEEVEQSARIIEQCVDLLEGWPEDERDIQANVPRTLKPEAGTETYRTVEGAKGELGVYIRADGTEKPGRFKIRSPCFSNLSALKEMSTGEYIPDLVATLGSLDVILGEVDR	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	562 (488)
Sequences:	821 (517)
Seq/√Len:	23.4

ECOLI - NUOCD HYCE HYFG
HALSA - Q9HRL9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
370_P	463_E	6.627	1.00
439_E	453_E	4.591	1.00
417_D	422_R	4.360	1.00
229_R	558_G	4.321	1.00
406_V	533_A	3.979	1.00
279_Y	350_D	3.955	1.00
441_G	446_S	3.950	1.00
435_D	457_Q	3.703	1.00
256_G	259_L	3.684	1.00
283_L	347_V	3.469	1.00
367_D	463_E	3.445	1.00
112_S	137_Y	3.422	1.00
396_L	406_V	3.303	1.00
193_L	543_I	3.286	1.00
434_W	464_Q	3.220	1.00
159_L	236_Q	3.115	1.00
252_D	556_I	3.051	1.00
111_V	138_D	2.830	0.99
394_G	549_T	2.817	0.99
360_E	364_D	2.809	0.99
233_Q	236_Q	2.737	0.99
537_M	553_L	2.607	0.99
374_D	456_E	2.561	0.99
417_D	436_V	2.521	0.99
271_L	495_T	2.506	0.98
282_I	470_E	2.477	0.98
140_H	143_L	2.444	0.98
288_G	426_Y	2.410	0.98
331_D	361_S	2.384	0.98
244_I	264_Y	2.368	0.98
277_P	280_A	2.303	0.97
366_L	463_E	2.256	0.97
208_V	546_L	2.206	0.96
329_L	338_M	2.171	0.96
130_Y	143_L	2.171	0.96
279_Y	470_E	2.154	0.96
56_Q	117_P	2.146	0.96
363_R	467_D	2.132	0.96
302_T	306_D	2.095	0.95
254_G	554_D	2.075	0.95
422_R	436_V	2.067	0.95
278_E	431_E	2.058	0.95
518_P	521_F	2.016	0.94
235_A	521_F	2.011	0.94
206_L	531_L	1.981	0.94
128_E	522_K	1.980	0.94
279_Y	472_W	1.974	0.93
208_V	557_L	1.948	0.93
75_T	86_I	1.943	0.93
306_D	554_D	1.923	0.93
208_V	220_V	1.887	0.92
455_V	462_I	1.865	0.91
133_V	520_R	1.858	0.91
272_A	489_P	1.842	0.91
286_M	465_C	1.839	0.91
303_F	390_T	1.822	0.90
396_L	401_A	1.819	0.90
267_T	510_I	1.813	0.90
204_G	253_Y	1.761	0.89
276_V	281_Q	1.761	0.89
252_D	559_E	1.743	0.88
556_I	559_E	1.719	0.87
434_W	461_I	1.717	0.87
285_T	465_C	1.711	0.87
541_E	549_T	1.708	0.87
266_R	427_G	1.699	0.87
470_E	474_E	1.680	0.86
254_G	559_E	1.672	0.86
91_K	94_D	1.648	0.85
434_W	437_V	1.629	0.84
206_L	557_L	1.626	0.84
285_T	428_Y	1.612	0.84
52_A	109_N	1.611	0.84
397_D	400_T	1.609	0.84
377_S	452_M	1.604	0.83
437_V	453_E	1.603	0.83
124_W	146_I	1.599	0.83
200_P	203_H	1.598	0.83
254_G	556_I	1.597	0.83
365_F	369_L	1.597	0.83
501_G	506_L	1.593	0.83
254_G	525_S	1.588	0.83
251_W	523_I	1.585	0.83
201_A	557_L	1.582	0.83
80_E	83_F	1.578	0.82
130_Y	137_Y	1.578	0.82
494_E	509_Y	1.578	0.82
290_L	325_V	1.571	0.82
508_V	523_I	1.564	0.82
370_P	460_R	1.544	0.81
146_I	333_T	1.540	0.81
245_M	265_A	1.536	0.81
370_P	459_A	1.524	0.80
210_T	551_G	1.524	0.80
142_N	221_N	1.517	0.80
195_I	551_G	1.511	0.80
85_S	101_I	1.504	0.79
275_D	281_Q	1.498	0.79
116_E	123_D	1.486	0.78
201_A	299_A	1.478	0.78
203_H	551_G	1.478	0.78
210_T	220_V	1.473	0.78
114_T	126_E	1.456	0.77
453_E	457_Q	1.453	0.77
494_E	511_R	1.432	0.76
525_S	556_I	1.431	0.76
350_D	472_W	1.416	0.75
55_V	59_L	1.411	0.75
511_R	519_G	1.408	0.74
287_G	341_Y	1.406	0.74
432_L	467_D	1.404	0.74
302_T	554_D	1.403	0.74
299_A	554_D	1.403	0.74
60_S	118_V	1.394	0.74
306_D	556_I	1.382	0.73
275_D	364_D	1.380	0.73
265_A	342_L	1.379	0.73
229_R	257_G	1.374	0.73
510_I	521_F	1.372	0.72
496_Y	507_G	1.370	0.72
259_L	502_A	1.360	0.72
195_I	547_V	1.360	0.72
256_G	306_D	1.358	0.72
203_H	550_L	1.358	0.72
423_D	436_V	1.352	0.71
112_S	129_A	1.350	0.71
61_T	66_A	1.349	0.71
285_T	432_L	1.345	0.71
206_L	299_A	1.345	0.71
256_G	559_E	1.344	0.71
232_E	520_R	1.337	0.70
203_H	306_D	1.329	0.70
81_D	84_E	1.321	0.70
55_V	325_V	1.312	0.69
225_G	322_R	1.302	0.68
282_I	351_I	1.290	0.68
192_F	551_G	1.289	0.68
278_E	281_Q	1.285	0.67
235_A	248_P	1.284	0.67
249_D	340_N	1.281	0.67
269_E	284_R	1.280	0.67
361_S	364_D	1.264	0.66
420_V	496_Y	1.264	0.66
299_A	557_L	1.263	0.66
55_V	93_D	1.261	0.66
111_V	136_E	1.260	0.66
285_T	427_G	1.251	0.65
443_D	446_S	1.246	0.65
426_Y	464_Q	1.245	0.65
508_V	521_F	1.238	0.64
417_D	423_D	1.235	0.64
350_D	470_E	1.228	0.64
513_D	516_E	1.223	0.63
85_S	112_S	1.221	0.63
59_L	89_L	1.210	0.63
217_V	541_E	1.209	0.63
253_Y	291_C	1.206	0.62
431_E	468_L	1.206	0.62
439_E	446_S	1.201	0.62
347_V	369_L	1.194	0.62
433_D	464_Q	1.188	0.61
432_L	465_C	1.185	0.61
254_G	502_A	1.183	0.61
249_D	261_E	1.183	0.61
262_W	288_G	1.180	0.61
293_I	455_V	1.177	0.60
400_T	536_E	1.172	0.60
229_R	252_D	1.171	0.60
367_D	370_P	1.171	0.60
445_Y	449_L	1.171	0.60
57_D	60_S	1.170	0.60
200_P	531_L	1.168	0.60
533_A	537_M	1.165	0.60
328_I	365_F	1.162	0.59
531_L	557_L	1.160	0.59
116_E	544_P	1.157	0.59
256_G	554_D	1.153	0.59
251_W	508_V	1.150	0.59
143_L	271_L	1.149	0.58
252_D	554_D	1.149	0.58
200_P	550_L	1.148	0.58
159_L	233_Q	1.135	0.58
268_A	510_I	1.130	0.57
112_S	135_V	1.130	0.57
364_D	471_G	1.128	0.57
377_S	456_E	1.126	0.57
435_D	460_R	1.119	0.56
373_L	455_V	1.115	0.56
195_I	546_L	1.113	0.56
210_T	550_L	1.109	0.56
301_G	451_R	1.106	0.56
163_Q	234_M	1.102	0.55
320_R	324_V	1.101	0.55
195_I	201_A	1.101	0.55
406_V	410_V	1.097	0.55
235_A	244_I	1.092	0.55
271_L	512_A	1.089	0.54
399_E	468_L	1.088	0.54
133_V	437_V	1.087	0.54
322_R	337_M	1.087	0.54
132_L	283_L	1.085	0.54
369_L	455_V	1.076	0.53
502_A	525_S	1.072	0.53
306_D	559_E	1.071	0.53
550_L	557_L	1.070	0.53
229_R	543_I	1.070	0.53
81_D	86_I	1.066	0.53
270_D	497_R	1.064	0.53
244_I	521_F	1.062	0.52
418_Y	424_D	1.059	0.52
393_T	542_Y	1.059	0.52
54_A	57_D	1.057	0.52
303_F	497_R	1.056	0.52
432_L	461_I	1.053	0.52
250_R	323_E	1.049	0.52
439_E	450_V	1.046	0.51
51_R	54_A	1.044	0.51
387_Q	445_Y	1.040	0.51
60_S	66_A	1.040	0.51
200_P	210_T	1.039	0.51
464_Q	468_L	1.033	0.50
190_T	211_V	1.028	0.50
192_F	221_N	1.027	0.50
162_N	165_K	1.027	0.50
491_A	515_T	1.025	0.50
525_S	554_D	1.014	0.49
305_L	554_D	1.013	0.49
219_D	286_M	1.011	0.49
380_I	448_L	1.007	0.49
123_D	140_H	1.005	0.48
291_C	339_L	1.004	0.48
256_G	502_A	1.002	0.48
106_S	109_N	1.002	0.48
199_H	306_D	1.000	0.48
282_I	468_L	1.000	0.48
260_N	508_V	0.999	0.48
312_T	317_Y	0.995	0.48
185_A	189_D	0.995	0.48
328_I	342_L	0.995	0.48
350_D	436_V	0.992	0.48
510_I	518_P	0.992	0.48
253_Y	557_L	0.990	0.47
554_D	559_E	0.983	0.47
256_G	556_I	0.983	0.47
133_V	157_L	0.983	0.47
531_L	560_V	0.983	0.47
240_Y	243_Q	0.981	0.47
185_A	190_T	0.973	0.46
74_V	85_S	0.973	0.46
114_T	117_P	0.962	0.45
195_I	210_T	0.958	0.45
198_H	557_L	0.956	0.45
57_D	61_T	0.956	0.45
387_Q	391_V	0.955	0.45
139_D	463_E	0.955	0.45
208_V	503_K	0.954	0.45
501_G	525_S	0.953	0.45
309_G	411_A	0.952	0.45
252_D	306_D	0.951	0.45
55_V	113_E	0.948	0.44
144_E	323_E	0.944	0.44
321_D	368_E	0.943	0.44
199_H	203_H	0.941	0.44
51_R	57_D	0.940	0.44
158_G	233_Q	0.936	0.44
201_A	527_C	0.928	0.43
83_F	101_I	0.928	0.43
254_G	560_V	0.926	0.43
397_D	491_A	0.926	0.43
398_Y	442_G	0.925	0.43
282_I	431_E	0.923	0.43
107_R	110_P	0.923	0.43
203_H	206_L	0.922	0.43
203_H	557_L	0.921	0.43
199_H	554_D	0.917	0.42
335_Q	338_M	0.915	0.42
378_D	382_S	0.914	0.42
124_W	528_F	0.912	0.42
143_L	146_I	0.906	0.42
411_A	530_N	0.904	0.41
159_L	519_G	0.903	0.41
76_A	133_V	0.902	0.41
206_L	546_L	0.902	0.41
420_V	498_T	0.900	0.41
304_C	380_I	0.900	0.41
193_L	229_R	0.900	0.41
206_L	551_G	0.897	0.41
286_M	424_D	0.897	0.41
304_C	448_L	0.896	0.41
426_Y	524_R	0.894	0.41
381_T	445_Y	0.890	0.41
457_Q	460_R	0.887	0.40
60_S	65_E	0.887	0.40
200_P	206_L	0.887	0.40
200_P	551_G	0.885	0.40
280_A	345_G	0.884	0.40
71_L	74_V	0.884	0.40
238_G	247_Y	0.882	0.40
460_R	464_Q	0.876	0.40
525_S	559_E	0.875	0.40
205_V	444_N	0.870	0.39
547_V	557_L	0.870	0.39
434_W	438_T	0.870	0.39
227_L	322_R	0.867	0.39
54_A	61_T	0.866	0.39
288_G	444_N	0.865	0.39
258_I	287_G	0.865	0.39
280_A	347_V	0.864	0.39
205_V	557_L	0.862	0.39
275_D	278_E	0.861	0.39
370_P	374_D	0.861	0.39
160_D	233_Q	0.858	0.38
363_R	463_E	0.857	0.38
195_I	206_L	0.857	0.38
128_E	523_I	0.856	0.38
128_E	232_E	0.855	0.38
198_H	531_L	0.854	0.38
199_H	561_D	0.854	0.38
140_H	260_N	0.851	0.38
203_H	554_D	0.850	0.38
82_R	85_S	0.849	0.38
384_E	499_V	0.847	0.38
252_D	503_K	0.846	0.38
52_A	57_D	0.845	0.38
353_E	514_G	0.845	0.38
61_T	67_G	0.843	0.37
310_D	547_V	0.842	0.37
461_I	465_C	0.842	0.37
61_T	74_V	0.842	0.37
80_E	101_I	0.838	0.37
324_V	368_E	0.837	0.37
470_E	475_D	0.836	0.37
296_H	454_E	0.835	0.37
175_K	179_E	0.833	0.37
240_Y	512_A	0.830	0.37
253_Y	556_I	0.827	0.36
198_H	201_A	0.825	0.36
268_A	501_G	0.823	0.36
121_T	505_E	0.823	0.36
283_L	350_D	0.823	0.36
295_C	506_L	0.823	0.36
430_P	433_D	0.822	0.36
386_F	390_T	0.822	0.36
200_P	557_L	0.821	0.36
254_G	306_D	0.820	0.36
56_Q	72_S	0.820	0.36
527_C	559_E	0.819	0.36
502_A	554_D	0.819	0.36
399_E	471_G	0.819	0.36
278_E	450_V	0.818	0.36
124_W	225_G	0.818	0.36
84_E	88_H	0.817	0.36
129_A	135_V	0.816	0.36
329_L	333_T	0.816	0.36
301_G	503_K	0.816	0.36
198_H	202_T	0.816	0.36
204_G	291_C	0.815	0.36
161_Y	164_N	0.815	0.36
265_A	276_V	0.813	0.35
223_D	247_Y	0.812	0.35
101_I	380_I	0.812	0.35
321_D	376_Y	0.811	0.35
58_V	61_T	0.808	0.35
381_T	452_M	0.805	0.35
294_A	333_T	0.804	0.35
391_V	445_Y	0.803	0.35
251_W	558_G	0.803	0.35
249_D	339_L	0.803	0.35
261_E	342_L	0.802	0.35
133_V	159_L	0.801	0.35
396_L	414_S	0.796	0.34
309_G	400_T	0.796	0.34
203_H	299_A	0.792	0.34
225_G	306_D	0.792	0.34
314_I	411_A	0.790	0.34
53_D	56_Q	0.790	0.34
137_Y	141_P	0.790	0.34
59_L	63_K	0.790	0.34
224_I	531_L	0.789	0.34
239_T	475_D	0.789	0.34
496_Y	510_I	0.789	0.34
54_A	66_A	0.787	0.34
315_F	319_M	0.787	0.34
124_W	535_K	0.786	0.34
302_T	556_I	0.785	0.34
75_T	88_H	0.784	0.34
459_A	467_D	0.784	0.34
291_C	559_E	0.783	0.34
453_E	456_E	0.783	0.34
157_L	228_H	0.779	0.33
202_T	394_G	0.777	0.33
131_D	155_H	0.772	0.33
265_A	375_E	0.768	0.33
542_Y	547_V	0.767	0.33
199_H	550_L	0.767	0.33
202_T	557_L	0.766	0.32
205_V	220_V	0.766	0.32
299_A	548_A	0.766	0.32
51_R	80_E	0.762	0.32
537_M	555_V	0.762	0.32
53_D	61_T	0.761	0.32
109_N	135_V	0.761	0.32
402_K	416_V	0.758	0.32
56_Q	60_S	0.757	0.32
132_L	288_G	0.756	0.32
295_C	553_L	0.756	0.32
534_L	557_L	0.756	0.32
207_H	226_Y	0.751	0.32
291_C	557_L	0.750	0.32
205_V	503_K	0.750	0.32
282_I	465_C	0.748	0.31
323_E	492_G	0.748	0.31
206_L	224_I	0.746	0.31
252_D	525_S	0.746	0.31
322_R	329_L	0.746	0.31
437_V	464_Q	0.746	0.31
208_V	531_L	0.745	0.31
192_F	550_L	0.745	0.31
363_R	466_V	0.743	0.31
89_L	139_D	0.742	0.31
424_D	523_I	0.741	0.31
395_V	515_T	0.740	0.31
302_T	559_E	0.739	0.31
546_L	551_G	0.738	0.31
407_T	530_N	0.737	0.31
192_F	533_A	0.735	0.31
161_Y	392_N	0.735	0.31
449_L	453_E	0.734	0.31
531_L	547_V	0.734	0.31
398_Y	414_S	0.734	0.31
87_Y	217_V	0.733	0.30
146_I	445_Y	0.733	0.30
277_P	473_P	0.733	0.30
306_D	551_G	0.732	0.30
439_E	449_L	0.732	0.30
227_L	410_V	0.732	0.30
51_R	56_Q	0.731	0.30
236_Q	519_G	0.731	0.30
434_W	457_Q	0.728	0.30
264_Y	429_Y	0.726	0.30
360_E	440_D	0.725	0.30
213_D	218_A	0.725	0.30
114_T	422_R	0.723	0.30
217_V	367_D	0.723	0.30
299_A	551_G	0.723	0.30
271_L	343_R	0.722	0.30
110_P	135_V	0.722	0.30
201_A	531_L	0.721	0.30
105_T	109_N	0.721	0.30
546_L	550_L	0.721	0.30
274_I	434_W	0.721	0.30
198_H	206_L	0.718	0.30
256_G	302_T	0.717	0.30
280_A	469_L	0.715	0.29
110_P	160_D	0.713	0.29
299_A	302_T	0.713	0.29
298_L	554_D	0.711	0.29
201_A	547_V	0.710	0.29
294_A	298_L	0.709	0.29
146_I	528_F	0.707	0.29
325_V	551_G	0.707	0.29
274_I	373_L	0.706	0.29
144_E	221_N	0.702	0.29
236_Q	520_R	0.700	0.29
219_D	535_K	0.700	0.29
492_G	514_G	0.700	0.29
201_A	546_L	0.699	0.28
239_T	243_Q	0.697	0.28
422_R	434_W	0.695	0.28
254_G	302_T	0.693	0.28
551_G	557_L	0.692	0.28
398_Y	416_V	0.691	0.28
303_F	525_S	0.687	0.28
110_P	375_E	0.686	0.28
252_D	256_G	0.683	0.28
203_H	302_T	0.681	0.27
323_E	326_Q	0.681	0.27
302_T	502_A	0.680	0.27
281_Q	497_R	0.678	0.27
401_A	411_A	0.677	0.27
59_L	66_A	0.676	0.27
262_W	268_A	0.676	0.27
115_A	497_R	0.675	0.27
298_L	312_T	0.674	0.27
420_V	505_E	0.674	0.27
260_N	538_S	0.674	0.27
280_A	284_R	0.674	0.27
203_H	531_L	0.674	0.27
279_Y	434_W	0.673	0.27
275_D	399_E	0.671	0.27
205_V	538_S	0.671	0.27
216_Q	393_T	0.671	0.27
232_E	462_I	0.670	0.27
396_L	537_M	0.670	0.27
409_P	501_G	0.669	0.27
90_R	94_D	0.668	0.27
195_I	557_L	0.667	0.27
215_E	306_D	0.666	0.27
201_A	550_L	0.666	0.27
299_A	550_L	0.665	0.27
418_Y	423_D	0.664	0.27
490_E	518_P	0.663	0.26
472_W	475_D	0.662	0.26
489_P	492_G	0.662	0.26
132_L	148_L	0.662	0.26
62_L	99_V	0.661	0.26
549_T	555_V	0.660	0.26
206_L	220_V	0.660	0.26
203_H	210_T	0.660	0.26
76_A	84_E	0.660	0.26
277_P	409_P	0.660	0.26
187_D	393_T	0.659	0.26
248_P	317_Y	0.658	0.26
455_V	467_D	0.655	0.26
253_Y	547_V	0.655	0.26
54_A	58_V	0.654	0.26
61_T	65_E	0.654	0.26
220_V	557_L	0.654	0.26
306_D	525_S	0.653	0.26
227_L	534_L	0.652	0.26
300_L	394_G	0.651	0.26
52_A	61_T	0.651	0.26
373_L	452_M	0.651	0.26
88_H	93_D	0.650	0.26
131_D	558_G	0.650	0.26
94_D	97_Q	0.650	0.26
132_L	416_V	0.649	0.26
386_F	543_I	0.649	0.26
125_H	508_V	0.648	0.26
264_Y	314_I	0.648	0.26
100_S	103_V	0.647	0.26
56_Q	62_L	0.647	0.26
203_H	561_D	0.645	0.26
202_T	206_L	0.645	0.26
367_D	460_R	0.645	0.26
495_T	540_G	0.644	0.25
192_F	503_K	0.643	0.25
128_E	521_F	0.643	0.25
128_E	140_H	0.640	0.25
459_A	473_P	0.640	0.25
89_L	92_Y	0.639	0.25
147_L	294_A	0.638	0.25
301_G	318_A	0.638	0.25
286_M	467_D	0.635	0.25
367_D	387_Q	0.633	0.25
94_D	98_E	0.633	0.25
131_D	323_E	0.631	0.25
531_L	550_L	0.629	0.25
51_R	62_L	0.629	0.25
204_G	310_D	0.627	0.25
65_E	93_D	0.627	0.25
187_D	200_P	0.626	0.25
220_V	550_L	0.626	0.25
225_G	294_A	0.625	0.24
257_G	298_L	0.623	0.24
54_A	65_E	0.623	0.24
220_V	538_S	0.622	0.24
210_T	299_A	0.622	0.24
277_P	501_G	0.622	0.24
238_G	243_Q	0.621	0.24
305_L	525_S	0.620	0.24
226_Y	382_S	0.620	0.24
77_E	511_R	0.618	0.24
341_Y	349_W	0.615	0.24
209_E	221_N	0.615	0.24
283_L	455_V	0.615	0.24
125_H	529_S	0.613	0.24
299_A	547_V	0.613	0.24
217_V	538_S	0.612	0.24
66_A	81_D	0.612	0.24
298_L	551_G	0.612	0.24
205_V	209_E	0.612	0.24
330_E	514_G	0.610	0.24
366_L	467_D	0.610	0.24
433_D	462_I	0.609	0.24
547_V	550_L	0.607	0.24
53_D	516_E	0.606	0.23
139_D	324_V	0.605	0.23
146_I	249_D	0.605	0.23
85_S	133_V	0.603	0.23
133_V	233_Q	0.602	0.23
411_A	418_Y	0.601	0.23
320_R	372_R	0.600	0.23
306_D	550_L	0.599	0.23
280_A	350_D	0.599	0.23
246_P	340_N	0.598	0.23
327_N	335_Q	0.597	0.23
312_T	379_L	0.596	0.23
395_V	398_Y	0.596	0.23
286_M	435_D	0.596	0.23
235_A	553_L	0.595	0.23
411_A	416_V	0.595	0.23
53_D	94_D	0.594	0.23
295_C	301_G	0.594	0.23
248_P	297_M	0.591	0.23
364_D	468_L	0.590	0.23
293_I	510_I	0.589	0.23
433_D	491_A	0.587	0.23
300_L	448_L	0.587	0.23
299_A	546_L	0.586	0.22
198_H	295_C	0.584	0.22
422_R	426_Y	0.583	0.22
52_A	67_G	0.582	0.22
124_W	305_L	0.581	0.22
198_H	411_A	0.580	0.22
198_H	224_I	0.580	0.22
359_F	369_L	0.579	0.22
555_V	559_E	0.578	0.22
548_A	557_L	0.578	0.22
195_I	550_L	0.577	0.22
204_G	547_V	0.577	0.22
295_C	298_L	0.576	0.22
286_M	469_L	0.576	0.22
113_E	329_L	0.575	0.22
452_M	457_Q	0.574	0.22
412_R	500_E	0.572	0.22
317_Y	320_R	0.572	0.22
428_Y	432_L	0.572	0.22
258_I	442_G	0.572	0.22
550_L	554_D	0.570	0.22
281_Q	427_G	0.568	0.22
96_T	101_I	0.568	0.22
530_N	555_V	0.567	0.22
555_V	558_G	0.567	0.22
187_D	190_T	0.567	0.22
353_E	382_S	0.566	0.22
302_T	525_S	0.565	0.21
556_I	560_V	0.565	0.21
53_D	57_D	0.564	0.21
366_L	370_P	0.561	0.21
60_S	97_Q	0.560	0.21
198_H	555_V	0.560	0.21
102_I	105_T	0.560	0.21
193_L	444_N	0.559	0.21
112_S	548_A	0.558	0.21
201_A	551_G	0.557	0.21
118_V	274_I	0.556	0.21
114_T	141_P	0.555	0.21
118_V	440_D	0.555	0.21
406_V	409_P	0.554	0.21
422_R	429_Y	0.554	0.21
334_G	346_G	0.553	0.21
305_L	559_E	0.552	0.21
126_E	524_R	0.552	0.21
257_G	339_L	0.552	0.21
66_A	94_D	0.552	0.21
322_R	503_K	0.552	0.21
303_F	413_G	0.552	0.21
294_A	326_Q	0.551	0.21
158_G	236_Q	0.551	0.21
132_L	152_W	0.550	0.21
201_A	206_L	0.550	0.21
275_D	360_E	0.550	0.21
196_G	545_D	0.549	0.21
233_Q	520_R	0.549	0.21
206_L	209_E	0.548	0.21
239_T	441_G	0.547	0.21
287_G	379_L	0.547	0.21
198_H	547_V	0.547	0.21
542_Y	550_L	0.547	0.21
304_C	386_F	0.547	0.21
375_E	425_P	0.546	0.21
59_L	115_A	0.545	0.21
257_G	337_M	0.543	0.20
513_D	517_K	0.542	0.20
341_Y	514_G	0.541	0.20
240_Y	268_A	0.539	0.20
145_R	553_L	0.538	0.20
205_V	548_A	0.538	0.20
51_R	65_E	0.538	0.20
294_A	325_V	0.537	0.20
139_D	273_D	0.536	0.20
147_L	225_G	0.536	0.20
57_D	99_V	0.536	0.20
55_V	66_A	0.535	0.20
354_P	468_L	0.535	0.20
58_V	83_F	0.534	0.20
420_V	533_A	0.534	0.20
432_L	490_E	0.534	0.20
135_V	416_V	0.533	0.20
435_D	453_E	0.533	0.20
54_A	217_V	0.533	0.20
417_D	438_T	0.531	0.20
115_A	188_S	0.529	0.20
438_T	441_G	0.528	0.20
254_G	503_K	0.528	0.20
209_E	503_K	0.527	0.20
102_I	490_E	0.527	0.20
264_Y	462_I	0.526	0.20
147_L	194_N	0.525	0.20
138_D	450_V	0.525	0.20
210_T	557_L	0.524	0.20
73_C	77_E	0.524	0.20
488_K	515_T	0.523	0.20
220_V	546_L	0.522	0.20
274_I	282_I	0.522	0.20
146_I	428_Y	0.522	0.20
502_A	555_V	0.522	0.20
210_T	546_L	0.522	0.20
302_T	451_R	0.521	0.19
143_L	510_I	0.521	0.19
221_N	551_G	0.519	0.19
266_R	497_R	0.519	0.19
130_Y	136_E	0.517	0.19
260_N	506_L	0.517	0.19
444_N	549_T	0.517	0.19
253_Y	555_V	0.516	0.19
89_L	98_E	0.516	0.19
256_G	294_A	0.515	0.19
227_L	558_G	0.515	0.19
538_S	549_T	0.514	0.19
160_D	369_L	0.514	0.19
155_H	233_Q	0.514	0.19
82_R	86_I	0.512	0.19
254_G	299_A	0.510	0.19
335_Q	375_E	0.510	0.19
85_S	526_P	0.509	0.19
195_I	203_H	0.509	0.19
437_V	457_Q	0.507	0.19
205_V	551_G	0.507	0.19
312_T	505_E	0.506	0.19
104_P	276_V	0.505	0.19
273_D	399_E	0.504	0.19
80_E	106_S	0.503	0.19
205_V	310_D	0.503	0.19
506_L	526_P	0.503	0.19
247_Y	501_G	0.503	0.19
370_P	456_E	0.502	0.19
299_A	531_L	0.501	0.19
306_D	322_R	0.501	0.19
384_E	438_T	0.501	0.19
284_R	429_Y	0.500	0.19

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3i9v4	1	0.6352	100	0.475	Contact Map
4omfA	1	0.621	100	0.579	Contact Map
4kn9L	2	0.6263	100	0.586	Contact Map
3ze9B	1	0.6299	100	0.586	Contact Map
4uqlQ	1	0.6495	100	0.598	Contact Map
4u9hL	1	0.6388	100	0.599	Contact Map
1e3dB	1	0.6459	100	0.612	Contact Map
1yq9H	1	0.6352	100	0.614	Contact Map
4ue3L	2	0.6655	100	0.622	Contact Map
3myrB	2	0.6423	100	0.631	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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