GREMLIN Database
Q9HRL7 - NADH dehydrogenase/oxidoreductase-like protein
UniProt: Q9HRL7 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 153 (124)
Sequences: 1443 (638)
Seq/√Len: 57.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
89_E99_L4.8791.00
56_V91_V4.0851.00
109_T112_D3.2431.00
48_I94_V2.9911.00
7_S11_T2.8221.00
6_K9_A2.4291.00
89_E97_I2.2351.00
29_A104_E2.1521.00
12_M15_A2.1451.00
65_V74_Q2.0541.00
59_N83_I2.0091.00
24_E28_E1.9861.00
49_W66_T1.9201.00
23_V30_P1.8390.99
32_V103_F1.8010.99
42_F97_I1.7600.99
4_L8_M1.7510.99
116_N119_Q1.6660.99
15_A20_T1.5970.99
80_G113_L1.5850.98
14_H17_S1.5760.98
39_V102_N1.5570.98
51_R64_I1.5540.98
54_E63_Q1.5230.98
40_H79_V1.5140.98
24_E27_E1.5110.98
52_Q56_V1.5070.98
29_A103_F1.4860.98
115_F119_Q1.4780.98
48_I51_R1.4410.97
7_S10_T1.3990.97
51_R55_N1.3890.96
3_G6_K1.3880.96
5_L9_A1.3840.96
41_K98_L1.3830.96
72_G75_Y1.3820.96
8_M11_T1.3480.96
13_K17_S1.3380.96
107_G113_L1.3330.95
46_R96_A1.3220.95
104_E113_L1.3160.95
48_I98_L1.3160.95
9_A13_K1.3080.95
49_W72_G1.3040.95
117_K121_K1.2640.94
45_E117_K1.2600.94
34_A101_E1.2370.93
59_N75_Y1.2000.92
81_Q99_L1.1900.92
62_I78_H1.1720.91
42_F96_A1.1410.90
51_R94_V1.1210.89
42_F120_L1.1100.89
64_I75_Y1.1050.89
25_Y104_E1.0750.87
45_E94_V1.0740.87
9_A12_M1.0400.85
88_C92_C1.0200.84
17_S34_A1.0190.84
48_I75_Y1.0150.84
75_Y117_K1.0030.83
4_L7_S1.0020.83
79_V115_F1.0010.83
42_F117_K0.9940.83
52_Q91_V0.9930.83
66_T70_R0.9840.82
43_S46_R0.9770.82
12_M16_L0.9670.81
51_R54_E0.9380.79
115_F122_N0.9380.79
119_Q122_N0.9250.78
107_G112_D0.9240.78
123_V127_N0.9180.77
5_L108_D0.9050.76
79_V84_Y0.9050.76
21_F24_E0.9030.76
56_V87_L0.9010.76
82_C88_C0.9010.76
52_Q81_Q0.8930.75
65_V73_E0.8930.75
54_E62_I0.8920.75
63_Q74_Q0.8850.75
91_V96_A0.8820.74
106_T109_T0.8700.73
77_L99_L0.8680.73
69_Q80_G0.8400.71
76_N116_N0.8360.70
40_H87_L0.8140.68
24_E29_A0.8050.67
3_G83_I0.8040.67
6_K12_M0.7980.67
19_D31_E0.7800.65
39_V84_Y0.7730.64
61_T83_I0.7670.64
85_C88_C0.7540.62
79_V97_I0.7510.62
52_Q55_N0.7430.61
71_N106_T0.7420.61
48_I68_N0.7390.61
30_P103_F0.7370.61
83_I87_L0.7370.61
55_N89_E0.7260.59
50_C53_C0.7260.59
47_C53_C0.7240.59
53_C57_C0.7240.59
50_C57_C0.7230.59
47_C50_C0.7230.59
47_C57_C0.7210.59
44_Q96_A0.7190.59
5_L111_H0.7130.58
53_C82_C0.7080.58
40_H100_T0.7040.57
64_I76_N0.6980.56
67_D123_V0.6970.56
20_T103_F0.6960.56
53_C85_C0.6910.56
50_C85_C0.6910.56
54_E64_I0.6900.56
47_C85_C0.6890.55
57_C85_C0.6890.55
41_K100_T0.6880.55
53_C92_C0.6720.54
103_F106_T0.6640.53
55_N70_R0.6640.53
23_V56_V0.6480.51
32_V36_F0.6430.50
111_H114_V0.6390.50
50_C82_C0.6360.50
16_L19_D0.6360.50
47_C82_C0.6340.49
57_C82_C0.6340.49
43_S66_T0.6330.49
78_H81_Q0.6310.49
105_F112_D0.6290.49
5_L13_K0.6270.49
40_H77_L0.6160.48
17_S20_T0.6140.47
42_F52_Q0.6140.47
6_K15_A0.6100.47
61_T97_I0.6060.46
61_T72_G0.6050.46
14_H23_V0.6020.46
50_C92_C0.6000.46
82_C85_C0.5990.46
57_C92_C0.5990.46
47_C92_C0.5990.46
49_W67_D0.5860.44
9_A17_S0.5860.44
11_T21_F0.5810.44
29_A34_A0.5760.43
89_E98_L0.5650.42
82_C92_C0.5640.42
22_T26_P0.5610.42
33_S84_Y0.5610.42
21_F108_D0.5600.41
85_C92_C0.5600.41
54_E108_D0.5570.41
61_T86_R0.5540.41
6_K23_V0.5520.41
96_A125_W0.5510.40
80_G110_K0.5500.40
33_S101_E0.5450.40
103_F113_L0.5420.40
87_L91_V0.5350.39
41_K124_P0.5340.39
7_S75_Y0.5310.38
63_Q76_N0.5310.38
84_Y105_F0.5300.38
112_D116_N0.5300.38
83_I90_E0.5300.38
41_K122_N0.5290.38
31_E74_Q0.5250.38
48_I96_A0.5190.37
55_N91_V0.5170.37
65_V71_N0.5160.37
77_L81_Q0.5140.37
53_C88_C0.5130.37
50_C88_C0.5130.37
57_C88_C0.5110.36
47_C88_C0.5110.36
46_R89_E0.5100.36
6_K14_H0.5070.36
28_E33_S0.5060.36
48_I52_Q0.5040.36
75_Y80_G0.5030.36
46_R98_L0.5000.35
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3i9v9 1 0.8431 99.9 0.509 Contact Map
1gteA 4 0.6928 99.5 0.678 Contact Map
1xerA 2 0.6471 99.5 0.684 Contact Map
5c4iB 1 0.6536 99.5 0.687 Contact Map
3i9v3 1 0.8954 99.5 0.689 Contact Map
2gmhA 1 0.7386 99.4 0.7 Contact Map
1hfeL 2 0.8497 99.4 0.701 Contact Map
2c42A 2 0.9935 99.4 0.707 Contact Map
4omfG 2 0.6601 99.4 0.709 Contact Map
1jb0C 1 0.5098 99.4 0.71 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0062 seconds.