Q9HRK7 - HALSA - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

Q9HRK7 - Methylmalonyl-CoA mutase, subunit alpha

UniProt:	Q9HRK7	Sequences: MEVDRLYTPADVADTDYNEDLGFPGEFPYTRGVYPTGYRGRTWTMRQFAGFGTAEETNERFHYLIDNGQTGLSTAFDMPSLMGLDSDHRMSLGEVGKEGVAVDTLRDMEILFDGIDLAAVSTSFTINPSAPVIYAMYLALADQQGVPREDIRGTLQNDMLKEFIAQKEWVVPPTPSLDLVTDVVEYCVAETPNFHPISVSGYHIREAGSTAVQELAFTLADGFAYVEDAIDRGLDVDAFAPQLSFFFNSHNAIFEEVAKFRAARRIYATLMDDWYGAEADAATQLKFHTQTAGQSLTAQQPKNNIARVTLQALAAVLGGSQSIHTNSFDEALALPSEEAVRVALRTQQIIAEESGAADIVDPLGGSFAVESLTNEIEAEAMAYLTEIKELGDGSVRDGVLAGIADGYFHREIQESAYEYQSRVDDGEETVVGVNEHEMDADTSPDTLHVDAEATRDRQLGRLSDVKAERDDDAVEATLAELRAGIRADENTIPYIVAAVKAYATMGEIMAVFKDEFGGYQETAAAA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	526 (502)
Sequences:	2414 (987)
Seq/√Len:	44.0

ECOLI - SCPA
HALSA - Q9HRK7 Q9HRZ1
SULSO - Q97W21

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
235_D	238_A	4.221	1.00
109_E	143_Q	4.193	1.00
422_R	428_E	3.568	1.00
226_V	271_M	3.555	1.00
379_E	382_A	3.490	1.00
104_T	465_V	3.401	1.00
482_R	514_D	3.398	1.00
142_D	500_K	3.269	1.00
210_T	415_S	3.236	1.00
305_I	342_V	3.206	1.00
86_S	101_A	3.122	1.00
86_S	103_D	3.073	1.00
57_T	61_F	2.879	1.00
247_F	263_A	2.855	1.00
230_I	236_V	2.824	1.00
302_K	328_F	2.812	1.00
269_T	381_M	2.801	1.00
237_D	278_E	2.771	1.00
240_A	271_M	2.736	1.00
199_V	243_L	2.728	1.00
139_A	500_K	2.646	1.00
254_F	368_A	2.641	1.00
352_E	436_H	2.620	1.00
375_E	379_E	2.579	1.00
399_V	408_F	2.572	1.00
4_D	11_D	2.510	1.00
471_D	475_E	2.499	1.00
265_R	374_N	2.483	1.00
121_S	152_R	2.462	1.00
485_I	512_F	2.446	1.00
227_E	388_K	2.443	1.00
470_D	473_A	2.432	1.00
147_P	150_D	2.352	1.00
227_E	275_Y	2.352	1.00
265_R	377_E	2.347	1.00
374_N	378_A	2.317	1.00
414_E	418_E	2.306	1.00
185_E	232_R	2.290	1.00
464_D	468_E	2.287	1.00
237_D	282_A	2.284	1.00
249_S	256_E	2.232	1.00
254_F	369_V	2.209	1.00
418_E	422_R	2.197	1.00
88_H	510_A	2.183	1.00
215_L	376_I	2.181	1.00
312_A	323_I	2.181	1.00
136_M	499_V	2.162	1.00
456_D	460_G	2.140	1.00
118_A	150_D	2.131	1.00
227_E	231_D	2.123	1.00
371_S	375_E	2.110	1.00
401_A	404_A	2.108	0.99
278_E	282_A	2.079	0.99
310_L	314_A	2.072	0.99
213_Q	411_E	2.048	0.99
253_I	257_V	2.036	0.99
27_F	268_A	2.033	0.99
271_M	277_A	2.032	0.99
289_T	320_S	2.029	0.99
201_G	218_T	2.017	0.99
429_T	435_E	2.008	0.99
30_T	265_R	1.985	0.99
460_G	464_D	1.959	0.99
240_A	282_A	1.955	0.99
310_L	350_I	1.946	0.99
473_A	476_A	1.927	0.99
221_D	399_V	1.914	0.99
223_F	384_L	1.909	0.99
386_E	411_E	1.907	0.99
484_G	494_Y	1.896	0.99
419_Y	428_E	1.896	0.99
118_A	146_V	1.879	0.99
495_I	499_V	1.874	0.99
426_G	435_E	1.866	0.99
381_M	385_T	1.851	0.99
272_D	283_T	1.851	0.99
302_K	338_E	1.848	0.99
499_V	508_I	1.822	0.99
55_E	457_R	1.811	0.98
303_N	349_I	1.796	0.98
459_L	463_S	1.795	0.98
309_T	354_S	1.768	0.98
305_I	328_F	1.768	0.98
142_D	148_R	1.767	0.98
252_A	358_D	1.704	0.98
474_V	503_A	1.699	0.98
185_E	189_A	1.694	0.98
288_H	322_S	1.677	0.97
498_A	503_A	1.671	0.97
214_E	259_K	1.638	0.97
480_E	497_A	1.635	0.97
223_F	270_L	1.631	0.97
217_F	407_Y	1.629	0.97
174_T	404_A	1.628	0.97
483_A	486_R	1.609	0.97
390_L	407_Y	1.589	0.96
383_Y	386_E	1.589	0.96
475_E	479_A	1.586	0.96
247_F	260_F	1.572	0.96
385_T	389_E	1.566	0.96
216_A	383_Y	1.557	0.96
219_L	222_G	1.549	0.96
178_D	516_F	1.540	0.96
45_M	344_L	1.539	0.96
251_N	311_Q	1.535	0.96
473_A	497_A	1.530	0.96
438_M	441_D	1.528	0.95
116_D	119_A	1.517	0.95
187_C	196_P	1.513	0.95
62_H	114_G	1.510	0.95
481_L	498_A	1.506	0.95
320_S	323_I	1.497	0.95
236_V	277_A	1.496	0.95
27_F	273_D	1.493	0.95
482_R	486_R	1.488	0.95
215_L	380_A	1.477	0.95
224_A	228_D	1.465	0.94
513_K	518_G	1.462	0.94
312_A	350_I	1.459	0.94
407_Y	411_E	1.456	0.94
210_T	213_Q	1.456	0.94
266_I	380_A	1.453	0.94
410_R	414_E	1.452	0.94
105_L	109_E	1.449	0.94
383_Y	407_Y	1.439	0.94
336_S	339_A	1.437	0.94
484_G	487_A	1.434	0.94
482_R	511_V	1.430	0.94
61_F	72_L	1.429	0.94
171_V	509_M	1.422	0.93
316_V	323_I	1.421	0.93
184_V	229_A	1.416	0.93
512_F	516_F	1.415	0.93
106_R	109_E	1.409	0.93
160_L	225_Y	1.407	0.93
44_T	71_G	1.405	0.93
477_T	501_A	1.400	0.93
390_L	402_G	1.394	0.93
509_M	513_K	1.393	0.93
383_Y	411_E	1.388	0.93
140_L	144_Q	1.386	0.92
148_R	186_Y	1.386	0.92
295_S	311_Q	1.378	0.92
46_R	71_G	1.375	0.92
466_K	474_V	1.374	0.92
453_A	457_R	1.373	0.92
55_E	110_I	1.370	0.92
363_L	369_V	1.370	0.92
181_T	228_D	1.366	0.92
218_T	247_F	1.363	0.92
480_E	484_G	1.356	0.92
327_S	340_V	1.356	0.92
3_V	368_A	1.355	0.92
148_R	190_E	1.339	0.91
138_L	186_Y	1.335	0.91
228_D	231_D	1.320	0.90
380_A	384_L	1.317	0.90
251_N	295_S	1.316	0.90
56_E	59_E	1.300	0.90
104_T	504_T	1.295	0.90
253_I	313_L	1.292	0.90
220_A	384_L	1.284	0.89
341_R	438_M	1.284	0.89
235_D	278_E	1.281	0.89
222_G	267_Y	1.272	0.89
386_E	390_L	1.272	0.89
224_A	400_L	1.269	0.89
378_A	382_A	1.269	0.89
401_A	405_D	1.263	0.88
422_R	427_E	1.262	0.88
212_V	379_E	1.257	0.88
212_V	216_A	1.250	0.88
306_A	309_T	1.246	0.88
308_V	311_Q	1.234	0.87
223_F	275_Y	1.228	0.87
341_R	345_R	1.225	0.87
138_L	496_V	1.214	0.86
317_L	363_L	1.212	0.86
81_L	166_Q	1.207	0.86
138_L	148_R	1.199	0.86
280_D	283_T	1.194	0.85
457_R	463_S	1.193	0.85
382_A	385_T	1.182	0.85
493_P	497_A	1.180	0.85
219_L	270_L	1.180	0.85
63_Y	337_E	1.179	0.85
495_I	508_I	1.175	0.84
58_N	114_G	1.172	0.84
213_Q	383_Y	1.172	0.84
268_A	283_T	1.172	0.84
488_D	491_T	1.172	0.84
160_L	399_V	1.169	0.84
205_R	292_A	1.167	0.84
484_G	489_E	1.164	0.84
479_A	483_A	1.162	0.84
510_A	514_D	1.160	0.84
237_D	240_A	1.153	0.83
429_T	434_N	1.146	0.83
446_T	450_D	1.142	0.83
402_G	407_Y	1.141	0.83
266_I	381_M	1.135	0.82
204_I	221_D	1.132	0.82
58_N	62_H	1.130	0.82
122_T	137_Y	1.128	0.82
184_V	232_R	1.127	0.82
313_L	317_L	1.124	0.82
370_E	373_T	1.123	0.82
252_A	428_E	1.121	0.82
155_L	196_P	1.117	0.81
510_A	513_K	1.116	0.81
457_R	460_G	1.113	0.81
471_D	474_V	1.112	0.81
270_L	381_M	1.106	0.81
30_T	377_E	1.104	0.81
219_L	266_I	1.102	0.80
160_L	400_L	1.101	0.80
48_F	81_L	1.098	0.80
241_P	282_A	1.093	0.80
453_A	456_D	1.093	0.80
189_A	238_A	1.092	0.80
55_E	59_E	1.091	0.80
421_S	425_D	1.088	0.80
459_L	466_K	1.084	0.79
100_V	111_L	1.079	0.79
263_A	285_L	1.079	0.79
402_G	408_F	1.079	0.79
78_M	81_L	1.078	0.79
104_T	466_K	1.072	0.79
409_H	413_Q	1.067	0.78
136_M	505_M	1.066	0.78
249_S	289_T	1.065	0.78
74_T	112_F	1.063	0.78
386_E	389_E	1.058	0.78
141_A	151_I	1.056	0.78
131_P	512_F	1.052	0.77
237_D	277_A	1.050	0.77
48_F	166_Q	1.045	0.77
481_L	494_Y	1.045	0.77
154_T	244_S	1.042	0.77
224_A	227_E	1.036	0.76
268_A	272_D	1.035	0.76
333_A	336_S	1.033	0.76
265_R	268_A	1.026	0.75
411_E	414_E	1.025	0.75
129_S	132_V	1.023	0.75
473_A	477_T	1.023	0.75
137_Y	141_A	1.020	0.75
477_T	480_E	1.019	0.75
249_S	260_F	1.016	0.75
74_T	111_L	1.010	0.74
463_S	467_A	1.009	0.74
186_Y	191_T	1.005	0.74
247_F	287_F	1.001	0.74
362_P	369_V	0.999	0.73
300_Q	345_R	0.999	0.73
6_L	360_V	0.993	0.73
48_F	75_A	0.987	0.73
81_L	167_K	0.984	0.72
46_R	123_S	0.982	0.72
45_M	348_Q	0.979	0.72
211_A	255_E	0.976	0.72
136_M	508_I	0.973	0.71
61_F	74_T	0.969	0.71
6_L	23_F	0.969	0.71
247_F	289_T	0.967	0.71
57_T	111_L	0.962	0.71
164_I	167_K	0.960	0.70
201_G	247_F	0.958	0.70
496_V	499_V	0.958	0.70
109_E	139_A	0.958	0.70
472_D	476_A	0.957	0.70
181_T	232_R	0.956	0.70
473_A	501_A	0.955	0.70
487_A	491_T	0.952	0.70
62_H	66_D	0.951	0.70
131_P	495_I	0.950	0.70
23_F	26_E	0.950	0.70
359_I	364_G	0.942	0.69
209_S	412_I	0.941	0.69
328_F	338_E	0.940	0.69
226_V	239_F	0.939	0.69
152_R	193_N	0.937	0.69
386_E	407_Y	0.933	0.68
27_F	269_T	0.929	0.68
132_V	509_M	0.924	0.67
63_Y	66_D	0.924	0.67
108_M	140_L	0.917	0.67
220_A	387_I	0.914	0.67
5_R	36_T	0.910	0.66
462_L	504_T	0.907	0.66
10_A	13_A	0.907	0.66
345_R	348_Q	0.901	0.65
474_V	478_L	0.901	0.65
496_V	500_K	0.900	0.65
492_I	495_I	0.897	0.65
277_A	282_A	0.894	0.65
254_F	363_L	0.893	0.65
81_L	98_E	0.892	0.65
405_D	408_F	0.892	0.65
138_L	191_T	0.886	0.64
511_V	515_E	0.884	0.64
148_R	496_V	0.880	0.64
426_G	429_T	0.879	0.64
333_A	446_T	0.876	0.63
492_I	496_V	0.873	0.63
153_G	194_F	0.872	0.63
211_A	250_H	0.870	0.63
309_T	319_G	0.869	0.63
290_Q	326_N	0.868	0.63
260_F	289_T	0.868	0.63
86_S	458_Q	0.866	0.62
314_A	317_L	0.866	0.62
483_A	489_E	0.866	0.62
258_A	372_L	0.863	0.62
217_F	383_Y	0.863	0.62
25_G	28_P	0.863	0.62
22_G	30_T	0.862	0.62
482_R	515_E	0.862	0.62
277_A	283_T	0.860	0.62
213_Q	415_S	0.859	0.62
110_I	113_D	0.856	0.61
384_L	388_K	0.854	0.61
479_A	482_R	0.852	0.61
253_I	350_I	0.852	0.61
382_A	386_E	0.849	0.61
300_Q	341_R	0.842	0.60
310_L	354_S	0.839	0.60
53_T	56_E	0.839	0.60
49_A	57_T	0.839	0.60
105_L	143_Q	0.836	0.60
446_T	449_V	0.835	0.60
78_M	166_Q	0.832	0.59
480_E	494_Y	0.832	0.59
245_F	285_L	0.831	0.59
23_F	360_V	0.831	0.59
248_N	294_Q	0.830	0.59
195_H	242_Q	0.830	0.59
216_A	380_A	0.829	0.59
184_V	196_P	0.827	0.59
8_T	23_F	0.826	0.59
24_P	31_R	0.824	0.59
64_L	340_V	0.822	0.58
230_I	277_A	0.818	0.58
129_S	509_M	0.818	0.58
199_V	226_V	0.817	0.58
295_S	308_V	0.817	0.58
257_V	317_L	0.815	0.58
467_A	476_A	0.813	0.57
316_V	356_A	0.808	0.57
437_E	441_D	0.807	0.57
237_D	241_P	0.800	0.56
78_M	169_W	0.800	0.56
180_V	197_I	0.799	0.56
462_L	466_K	0.796	0.56
216_A	411_E	0.796	0.56
294_Q	423_V	0.795	0.56
98_E	167_K	0.791	0.55
383_Y	387_I	0.789	0.55
477_T	482_R	0.789	0.55
135_A	186_Y	0.787	0.55
375_E	378_A	0.786	0.55
313_L	356_A	0.784	0.55
52_G	57_T	0.781	0.54
174_T	177_L	0.779	0.54
416_A	420_Q	0.778	0.54
25_G	32_G	0.777	0.54
230_I	275_Y	0.776	0.54
319_G	362_P	0.776	0.54
472_D	475_E	0.775	0.54
363_L	368_A	0.773	0.54
291_T	325_T	0.772	0.54
118_A	147_P	0.772	0.54
219_L	384_L	0.772	0.54
184_V	242_Q	0.770	0.53
7_Y	371_S	0.769	0.53
22_G	265_R	0.769	0.53
215_L	254_F	0.768	0.53
8_T	11_D	0.767	0.53
265_R	269_T	0.762	0.53
247_F	285_L	0.762	0.53
463_S	466_K	0.758	0.52
355_G	358_D	0.758	0.52
376_I	380_A	0.757	0.52
466_K	481_L	0.757	0.52
4_D	7_Y	0.755	0.52
184_V	197_I	0.755	0.52
205_R	211_A	0.753	0.52
254_F	366_S	0.752	0.52
123_S	154_T	0.751	0.52
54_A	111_L	0.750	0.51
198_S	246_F	0.749	0.51
467_A	479_A	0.749	0.51
189_A	473_A	0.748	0.51
27_F	272_D	0.748	0.51
48_F	168_E	0.748	0.51
477_T	498_A	0.747	0.51
326_N	330_E	0.745	0.51
293_G	330_E	0.744	0.51
480_E	483_A	0.743	0.51
497_A	500_K	0.740	0.51
497_A	501_A	0.739	0.50
25_G	29_Y	0.736	0.50
88_H	506_G	0.734	0.50
500_K	503_A	0.734	0.50
229_A	232_R	0.734	0.50
181_T	185_E	0.734	0.50
164_I	403_I	0.733	0.50
250_H	292_A	0.732	0.50
240_A	277_A	0.731	0.50
457_R	462_L	0.730	0.50
269_T	377_E	0.730	0.50
359_I	368_A	0.726	0.49
105_L	465_V	0.726	0.49
117_L	122_T	0.725	0.49
447_L	450_D	0.725	0.49
308_V	326_N	0.721	0.49
125_T	161_K	0.719	0.49
161_K	203_H	0.719	0.49
226_V	267_Y	0.717	0.48
33_V	284_Q	0.715	0.48
217_F	387_I	0.715	0.48
117_L	144_Q	0.714	0.48
31_R	364_G	0.714	0.48
271_M	283_T	0.712	0.48
485_I	491_T	0.712	0.48
461_R	464_D	0.711	0.48
63_Y	67_N	0.711	0.48
481_L	512_F	0.710	0.48
501_A	505_M	0.710	0.48
467_A	473_A	0.710	0.48
60_R	340_V	0.708	0.47
209_S	248_N	0.708	0.47
180_V	183_V	0.706	0.47
48_F	78_M	0.705	0.47
316_V	350_I	0.702	0.47
123_S	153_G	0.701	0.47
254_F	372_L	0.700	0.47
494_Y	498_A	0.699	0.47
112_F	115_I	0.699	0.47
171_V	512_F	0.698	0.46
489_E	493_P	0.697	0.46
246_F	290_Q	0.696	0.46
98_E	168_E	0.695	0.46
486_R	515_E	0.694	0.46
327_S	512_F	0.694	0.46
211_A	313_L	0.694	0.46
341_R	441_D	0.694	0.46
287_F	320_S	0.693	0.46
159_M	171_V	0.693	0.46
488_D	494_Y	0.693	0.46
84_L	90_M	0.692	0.46
180_V	184_V	0.691	0.46
250_H	256_E	0.689	0.46
423_V	430_V	0.689	0.46
202_Y	290_Q	0.686	0.45
23_F	35_P	0.684	0.45
478_L	481_L	0.683	0.45
204_I	412_I	0.682	0.45
106_R	465_V	0.682	0.45
135_A	492_I	0.682	0.45
186_Y	190_E	0.682	0.45
71_G	154_T	0.680	0.45
61_F	115_I	0.677	0.44
302_K	305_I	0.673	0.44
474_V	477_T	0.672	0.44
27_F	283_T	0.671	0.44
470_D	475_E	0.670	0.44
4_D	12_V	0.670	0.44
456_D	463_S	0.669	0.44
255_E	300_Q	0.668	0.44
35_P	284_Q	0.667	0.44
248_N	259_K	0.666	0.43
76_F	290_Q	0.666	0.43
34_Y	360_V	0.666	0.43
46_R	153_G	0.665	0.43
297_T	430_V	0.664	0.43
42_T	45_M	0.664	0.43
217_F	399_V	0.663	0.43
37_G	360_V	0.662	0.43
465_V	479_A	0.661	0.43
35_P	224_A	0.657	0.43
254_F	362_P	0.656	0.43
219_L	285_L	0.656	0.43
65_I	115_I	0.656	0.43
81_L	168_E	0.656	0.43
205_R	250_H	0.655	0.42
161_K	164_I	0.655	0.42
88_H	513_K	0.653	0.42
178_D	182_D	0.652	0.42
7_Y	368_A	0.651	0.42
25_G	31_R	0.650	0.42
266_I	270_L	0.650	0.42
490_N	495_I	0.649	0.42
226_V	275_Y	0.647	0.42
252_A	366_S	0.647	0.42
105_L	108_M	0.647	0.42
64_L	69_Q	0.646	0.42
73_S	347_Q	0.645	0.41
3_V	6_L	0.645	0.41
49_A	61_F	0.644	0.41
105_L	136_M	0.644	0.41
269_T	272_D	0.639	0.41
469_R	474_V	0.639	0.41
55_E	113_D	0.635	0.41
106_R	468_E	0.635	0.41
316_V	351_A	0.635	0.41
381_M	384_L	0.634	0.40
60_R	63_Y	0.634	0.40
270_L	519_Y	0.631	0.40
106_R	197_I	0.630	0.40
223_F	227_E	0.630	0.40
218_T	285_L	0.629	0.40
35_P	65_I	0.629	0.40
302_K	306_A	0.629	0.40
212_V	376_I	0.629	0.40
24_P	253_I	0.629	0.40
473_A	483_A	0.628	0.40
303_N	426_G	0.628	0.40
296_L	335_P	0.626	0.40
382_A	430_V	0.626	0.40
226_V	230_I	0.624	0.40
296_L	311_Q	0.623	0.39
351_A	357_A	0.622	0.39
55_E	461_R	0.622	0.39
477_T	481_L	0.621	0.39
460_G	468_E	0.620	0.39
325_T	347_Q	0.619	0.39
137_Y	281_A	0.619	0.39
387_I	431_V	0.618	0.39
109_E	144_Q	0.617	0.39
288_H	324_H	0.617	0.39
223_F	277_A	0.616	0.39
293_G	326_N	0.614	0.39
313_L	427_E	0.613	0.39
64_L	344_L	0.613	0.39
356_A	466_K	0.612	0.38
142_D	146_V	0.612	0.38
453_A	460_G	0.611	0.38
153_G	192_P	0.611	0.38
328_F	358_D	0.608	0.38
34_Y	425_D	0.607	0.38
455_R	459_L	0.607	0.38
202_Y	293_G	0.606	0.38
314_A	349_I	0.604	0.38
300_Q	441_D	0.604	0.38
204_I	399_V	0.604	0.38
3_V	359_I	0.603	0.38
478_L	482_R	0.603	0.38
431_V	435_E	0.603	0.38
238_A	282_A	0.602	0.38
349_I	431_V	0.601	0.37
256_E	311_Q	0.600	0.37
309_T	349_I	0.600	0.37
450_D	453_A	0.597	0.37
331_A	457_R	0.597	0.37
299_Q	470_D	0.597	0.37
491_T	512_F	0.597	0.37
488_D	514_D	0.596	0.37
135_A	139_A	0.596	0.37
236_V	275_Y	0.595	0.37
59_E	66_D	0.593	0.37
249_S	314_A	0.591	0.37
152_R	286_K	0.591	0.37
29_Y	280_D	0.591	0.37
46_R	154_T	0.591	0.37
43_W	259_K	0.590	0.36
132_V	508_I	0.590	0.36
158_D	292_A	0.590	0.36
32_G	364_G	0.589	0.36
350_I	441_D	0.587	0.36
449_V	455_R	0.587	0.36
211_A	295_S	0.587	0.36
202_Y	206_E	0.586	0.36
60_R	64_L	0.586	0.36
139_A	142_D	0.585	0.36
342_V	516_F	0.581	0.36
206_E	293_G	0.581	0.36
195_H	286_K	0.581	0.36
164_I	204_I	0.581	0.36
463_S	482_R	0.580	0.36
161_K	225_Y	0.580	0.36
485_I	515_E	0.580	0.36
482_R	519_Y	0.579	0.35
143_Q	500_K	0.579	0.35
199_V	218_T	0.579	0.35
185_E	228_D	0.578	0.35
200_S	326_N	0.578	0.35
312_A	325_T	0.578	0.35
55_E	89_R	0.576	0.35
125_T	203_H	0.575	0.35
470_D	478_L	0.575	0.35
178_D	488_D	0.575	0.35
390_L	411_E	0.574	0.35
88_H	92_L	0.573	0.35
511_V	514_D	0.572	0.35
419_Y	423_V	0.572	0.35
253_I	316_V	0.572	0.35
86_S	462_L	0.572	0.35
184_V	239_F	0.572	0.35
12_V	486_R	0.571	0.35
317_L	356_A	0.570	0.35
73_S	290_Q	0.570	0.35
466_K	470_D	0.570	0.35
219_L	223_F	0.570	0.35
46_R	73_S	0.570	0.35
302_K	342_V	0.570	0.35
349_I	429_T	0.569	0.35
278_E	283_T	0.569	0.35
467_A	486_R	0.569	0.35
251_N	354_S	0.569	0.35
189_A	486_R	0.568	0.35
438_M	442_T	0.568	0.35
491_T	495_I	0.568	0.35
46_R	322_S	0.567	0.34
173_P	176_S	0.566	0.34
223_F	276_G	0.565	0.34
303_N	438_M	0.564	0.34
230_I	235_D	0.564	0.34
138_L	430_V	0.564	0.34
48_F	57_T	0.564	0.34
352_E	428_E	0.563	0.34
65_I	118_A	0.562	0.34
92_L	459_L	0.561	0.34
281_A	284_Q	0.561	0.34
489_E	492_I	0.559	0.34
263_A	287_F	0.558	0.34
178_D	232_R	0.556	0.33
6_L	359_I	0.555	0.33
184_V	400_L	0.555	0.33
59_E	63_Y	0.555	0.33
255_E	372_L	0.555	0.33
250_H	311_Q	0.555	0.33
374_N	382_A	0.555	0.33
72_L	76_F	0.554	0.33
251_N	349_I	0.554	0.33
224_A	399_V	0.552	0.33
458_Q	461_R	0.552	0.33
390_L	405_D	0.552	0.33
213_Q	217_F	0.551	0.33
267_Y	380_A	0.550	0.33
475_E	482_R	0.550	0.33
238_A	241_P	0.550	0.33
75_A	125_T	0.550	0.33
407_Y	410_R	0.550	0.33
127_N	161_K	0.550	0.33
73_S	123_S	0.550	0.33
80_S	133_I	0.550	0.33
458_Q	462_L	0.550	0.33
476_A	479_A	0.549	0.33
182_D	185_E	0.549	0.33
62_H	113_D	0.549	0.33
404_A	423_V	0.548	0.33
34_Y	336_S	0.547	0.33
72_L	125_T	0.546	0.33
378_A	389_E	0.546	0.33
7_Y	11_D	0.546	0.33
299_Q	433_V	0.545	0.33
465_V	468_E	0.545	0.33
355_G	359_I	0.544	0.32
109_E	140_L	0.544	0.32
300_Q	342_V	0.543	0.32
211_A	376_I	0.542	0.32
69_Q	364_G	0.541	0.32
440_A	443_S	0.541	0.32
456_D	468_E	0.541	0.32
106_R	143_Q	0.540	0.32
207_A	347_Q	0.539	0.32
126_I	130_A	0.539	0.32
75_A	203_H	0.539	0.32
418_E	421_S	0.539	0.32
81_L	94_E	0.539	0.32
213_Q	408_F	0.538	0.32
6_L	24_P	0.537	0.32
204_I	209_S	0.537	0.32
300_Q	438_M	0.536	0.32
12_V	367_F	0.536	0.32
459_L	465_V	0.533	0.32
54_A	331_A	0.533	0.32
368_A	372_L	0.532	0.31
161_K	166_Q	0.531	0.31
238_A	448_H	0.531	0.31
59_E	430_V	0.531	0.31
441_D	520_Q	0.530	0.31
72_L	154_T	0.529	0.31
57_T	74_T	0.529	0.31
476_A	480_E	0.526	0.31
106_R	289_T	0.526	0.31
201_G	221_D	0.526	0.31
135_A	496_V	0.525	0.31
156_Q	246_F	0.525	0.31
374_N	475_E	0.525	0.31
198_S	244_S	0.524	0.31
82_M	518_G	0.523	0.31
79_P	91_S	0.522	0.31
410_R	430_V	0.522	0.31
200_S	246_F	0.522	0.31
287_F	290_Q	0.521	0.31
294_Q	458_Q	0.521	0.31
200_S	218_T	0.520	0.30
57_T	335_P	0.520	0.30
236_V	282_A	0.519	0.30
389_E	472_D	0.519	0.30
300_Q	344_L	0.518	0.30
117_L	137_Y	0.518	0.30
266_I	384_L	0.518	0.30
149_E	272_D	0.517	0.30
105_L	140_L	0.517	0.30
262_A	369_V	0.517	0.30
460_G	463_S	0.517	0.30
156_Q	220_A	0.516	0.30
50_G	330_E	0.516	0.30
466_K	506_G	0.516	0.30
222_G	245_F	0.516	0.30
453_A	463_S	0.516	0.30
45_M	351_A	0.515	0.30
364_G	367_F	0.514	0.30
469_R	472_D	0.514	0.30
310_L	356_A	0.514	0.30
197_I	229_A	0.513	0.30
137_Y	147_P	0.512	0.30
201_G	204_I	0.511	0.30
379_E	428_E	0.510	0.30
62_H	116_D	0.510	0.30
202_Y	324_H	0.509	0.30
506_G	510_A	0.509	0.30
420_Q	461_R	0.509	0.30
405_D	442_T	0.509	0.30
196_P	199_V	0.509	0.30
483_A	487_A	0.509	0.30
218_T	325_T	0.508	0.29
52_G	277_A	0.507	0.29
290_Q	324_H	0.507	0.29
42_T	436_H	0.505	0.29
48_F	167_K	0.505	0.29
437_E	463_S	0.505	0.29
212_V	255_E	0.504	0.29
466_K	504_T	0.504	0.29
269_T	273_D	0.504	0.29
5_R	441_D	0.504	0.29
309_T	428_E	0.503	0.29
480_E	489_E	0.503	0.29
343_A	412_I	0.503	0.29
134_Y	155_L	0.503	0.29
294_Q	518_G	0.502	0.29
487_A	515_E	0.502	0.29
50_G	202_Y	0.502	0.29
457_R	510_A	0.502	0.29
223_F	399_V	0.502	0.29
249_S	287_F	0.501	0.29
405_D	410_R	0.501	0.29
50_G	57_T	0.500	0.29
341_R	519_Y	0.500	0.29
33_V	411_E	0.500	0.29

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4r3uA	2	0.9753	100	0.052	Contact Map
2xijA	2	0.981	100	0.068	Contact Map
1reqA	1	0.9829	100	0.071	Contact Map
4xc8A	2	0.9639	100	0.111	Contact Map
1reqB	1	0.9125	100	0.226	Contact Map
3kp1A	2	0.8878	100	0.466	Contact Map
1ccwB	2	0.8365	100	0.784	Contact Map
3r12A	2	0.3612	38.9	0.981	Contact Map
2la2A	1	0.0646	32.7	0.982	Contact Map
1p8aA	1	0.2148	28	0.983	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0135 seconds.