GREMLIN Database
Q9HRK7 - Methylmalonyl-CoA mutase, subunit alpha
UniProt: Q9HRK7 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 526 (502)
Sequences: 2414 (987)
Seq/√Len: 44.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
235_D238_A4.2211.00
109_E143_Q4.1931.00
422_R428_E3.5681.00
226_V271_M3.5551.00
379_E382_A3.4901.00
104_T465_V3.4011.00
482_R514_D3.3981.00
142_D500_K3.2691.00
210_T415_S3.2361.00
305_I342_V3.2061.00
86_S101_A3.1221.00
86_S103_D3.0731.00
57_T61_F2.8791.00
247_F263_A2.8551.00
230_I236_V2.8241.00
302_K328_F2.8121.00
269_T381_M2.8011.00
237_D278_E2.7711.00
240_A271_M2.7361.00
199_V243_L2.7281.00
139_A500_K2.6461.00
254_F368_A2.6411.00
352_E436_H2.6201.00
375_E379_E2.5791.00
399_V408_F2.5721.00
4_D11_D2.5101.00
471_D475_E2.4991.00
265_R374_N2.4831.00
121_S152_R2.4621.00
485_I512_F2.4461.00
227_E388_K2.4431.00
470_D473_A2.4321.00
147_P150_D2.3521.00
227_E275_Y2.3521.00
265_R377_E2.3471.00
374_N378_A2.3171.00
414_E418_E2.3061.00
185_E232_R2.2901.00
464_D468_E2.2871.00
237_D282_A2.2841.00
249_S256_E2.2321.00
254_F369_V2.2091.00
418_E422_R2.1971.00
88_H510_A2.1831.00
215_L376_I2.1811.00
312_A323_I2.1811.00
136_M499_V2.1621.00
456_D460_G2.1401.00
118_A150_D2.1311.00
227_E231_D2.1231.00
371_S375_E2.1101.00
401_A404_A2.1080.99
278_E282_A2.0790.99
310_L314_A2.0720.99
213_Q411_E2.0480.99
253_I257_V2.0360.99
27_F268_A2.0330.99
271_M277_A2.0320.99
289_T320_S2.0290.99
201_G218_T2.0170.99
429_T435_E2.0080.99
30_T265_R1.9850.99
460_G464_D1.9590.99
240_A282_A1.9550.99
310_L350_I1.9460.99
473_A476_A1.9270.99
221_D399_V1.9140.99
223_F384_L1.9090.99
386_E411_E1.9070.99
484_G494_Y1.8960.99
419_Y428_E1.8960.99
118_A146_V1.8790.99
495_I499_V1.8740.99
426_G435_E1.8660.99
381_M385_T1.8510.99
272_D283_T1.8510.99
302_K338_E1.8480.99
499_V508_I1.8220.99
55_E457_R1.8110.98
303_N349_I1.7960.98
459_L463_S1.7950.98
309_T354_S1.7680.98
305_I328_F1.7680.98
142_D148_R1.7670.98
252_A358_D1.7040.98
474_V503_A1.6990.98
185_E189_A1.6940.98
288_H322_S1.6770.97
498_A503_A1.6710.97
214_E259_K1.6380.97
480_E497_A1.6350.97
223_F270_L1.6310.97
217_F407_Y1.6290.97
174_T404_A1.6280.97
483_A486_R1.6090.97
390_L407_Y1.5890.96
383_Y386_E1.5890.96
475_E479_A1.5860.96
247_F260_F1.5720.96
385_T389_E1.5660.96
216_A383_Y1.5570.96
219_L222_G1.5490.96
178_D516_F1.5400.96
45_M344_L1.5390.96
251_N311_Q1.5350.96
473_A497_A1.5300.96
438_M441_D1.5280.95
116_D119_A1.5170.95
187_C196_P1.5130.95
62_H114_G1.5100.95
481_L498_A1.5060.95
320_S323_I1.4970.95
236_V277_A1.4960.95
27_F273_D1.4930.95
482_R486_R1.4880.95
215_L380_A1.4770.95
224_A228_D1.4650.94
513_K518_G1.4620.94
312_A350_I1.4590.94
407_Y411_E1.4560.94
210_T213_Q1.4560.94
266_I380_A1.4530.94
410_R414_E1.4520.94
105_L109_E1.4490.94
383_Y407_Y1.4390.94
336_S339_A1.4370.94
484_G487_A1.4340.94
482_R511_V1.4300.94
61_F72_L1.4290.94
171_V509_M1.4220.93
316_V323_I1.4210.93
184_V229_A1.4160.93
512_F516_F1.4150.93
106_R109_E1.4090.93
160_L225_Y1.4070.93
44_T71_G1.4050.93
477_T501_A1.4000.93
390_L402_G1.3940.93
509_M513_K1.3930.93
383_Y411_E1.3880.93
140_L144_Q1.3860.92
148_R186_Y1.3860.92
295_S311_Q1.3780.92
46_R71_G1.3750.92
466_K474_V1.3740.92
453_A457_R1.3730.92
55_E110_I1.3700.92
363_L369_V1.3700.92
181_T228_D1.3660.92
218_T247_F1.3630.92
480_E484_G1.3560.92
327_S340_V1.3560.92
3_V368_A1.3550.92
148_R190_E1.3390.91
138_L186_Y1.3350.91
228_D231_D1.3200.90
380_A384_L1.3170.90
251_N295_S1.3160.90
56_E59_E1.3000.90
104_T504_T1.2950.90
253_I313_L1.2920.90
220_A384_L1.2840.89
341_R438_M1.2840.89
235_D278_E1.2810.89
222_G267_Y1.2720.89
386_E390_L1.2720.89
224_A400_L1.2690.89
378_A382_A1.2690.89
401_A405_D1.2630.88
422_R427_E1.2620.88
212_V379_E1.2570.88
212_V216_A1.2500.88
306_A309_T1.2460.88
308_V311_Q1.2340.87
223_F275_Y1.2280.87
341_R345_R1.2250.87
138_L496_V1.2140.86
317_L363_L1.2120.86
81_L166_Q1.2070.86
138_L148_R1.1990.86
280_D283_T1.1940.85
457_R463_S1.1930.85
382_A385_T1.1820.85
493_P497_A1.1800.85
219_L270_L1.1800.85
63_Y337_E1.1790.85
495_I508_I1.1750.84
58_N114_G1.1720.84
213_Q383_Y1.1720.84
268_A283_T1.1720.84
488_D491_T1.1720.84
160_L399_V1.1690.84
205_R292_A1.1670.84
484_G489_E1.1640.84
479_A483_A1.1620.84
510_A514_D1.1600.84
237_D240_A1.1530.83
429_T434_N1.1460.83
446_T450_D1.1420.83
402_G407_Y1.1410.83
266_I381_M1.1350.82
204_I221_D1.1320.82
58_N62_H1.1300.82
122_T137_Y1.1280.82
184_V232_R1.1270.82
313_L317_L1.1240.82
370_E373_T1.1230.82
252_A428_E1.1210.82
155_L196_P1.1170.81
510_A513_K1.1160.81
457_R460_G1.1130.81
471_D474_V1.1120.81
270_L381_M1.1060.81
30_T377_E1.1040.81
219_L266_I1.1020.80
160_L400_L1.1010.80
48_F81_L1.0980.80
241_P282_A1.0930.80
453_A456_D1.0930.80
189_A238_A1.0920.80
55_E59_E1.0910.80
421_S425_D1.0880.80
459_L466_K1.0840.79
100_V111_L1.0790.79
263_A285_L1.0790.79
402_G408_F1.0790.79
78_M81_L1.0780.79
104_T466_K1.0720.79
409_H413_Q1.0670.78
136_M505_M1.0660.78
249_S289_T1.0650.78
74_T112_F1.0630.78
386_E389_E1.0580.78
141_A151_I1.0560.78
131_P512_F1.0520.77
237_D277_A1.0500.77
48_F166_Q1.0450.77
481_L494_Y1.0450.77
154_T244_S1.0420.77
224_A227_E1.0360.76
268_A272_D1.0350.76
333_A336_S1.0330.76
265_R268_A1.0260.75
411_E414_E1.0250.75
129_S132_V1.0230.75
473_A477_T1.0230.75
137_Y141_A1.0200.75
477_T480_E1.0190.75
249_S260_F1.0160.75
74_T111_L1.0100.74
463_S467_A1.0090.74
186_Y191_T1.0050.74
247_F287_F1.0010.74
362_P369_V0.9990.73
300_Q345_R0.9990.73
6_L360_V0.9930.73
48_F75_A0.9870.73
81_L167_K0.9840.72
46_R123_S0.9820.72
45_M348_Q0.9790.72
211_A255_E0.9760.72
136_M508_I0.9730.71
61_F74_T0.9690.71
6_L23_F0.9690.71
247_F289_T0.9670.71
57_T111_L0.9620.71
164_I167_K0.9600.70
201_G247_F0.9580.70
496_V499_V0.9580.70
109_E139_A0.9580.70
472_D476_A0.9570.70
181_T232_R0.9560.70
473_A501_A0.9550.70
487_A491_T0.9520.70
62_H66_D0.9510.70
131_P495_I0.9500.70
23_F26_E0.9500.70
359_I364_G0.9420.69
209_S412_I0.9410.69
328_F338_E0.9400.69
226_V239_F0.9390.69
152_R193_N0.9370.69
386_E407_Y0.9330.68
27_F269_T0.9290.68
132_V509_M0.9240.67
63_Y66_D0.9240.67
108_M140_L0.9170.67
220_A387_I0.9140.67
5_R36_T0.9100.66
462_L504_T0.9070.66
10_A13_A0.9070.66
345_R348_Q0.9010.65
474_V478_L0.9010.65
496_V500_K0.9000.65
492_I495_I0.8970.65
277_A282_A0.8940.65
254_F363_L0.8930.65
81_L98_E0.8920.65
405_D408_F0.8920.65
138_L191_T0.8860.64
511_V515_E0.8840.64
148_R496_V0.8800.64
426_G429_T0.8790.64
333_A446_T0.8760.63
492_I496_V0.8730.63
153_G194_F0.8720.63
211_A250_H0.8700.63
309_T319_G0.8690.63
290_Q326_N0.8680.63
260_F289_T0.8680.63
86_S458_Q0.8660.62
314_A317_L0.8660.62
483_A489_E0.8660.62
258_A372_L0.8630.62
217_F383_Y0.8630.62
25_G28_P0.8630.62
22_G30_T0.8620.62
482_R515_E0.8620.62
277_A283_T0.8600.62
213_Q415_S0.8590.62
110_I113_D0.8560.61
384_L388_K0.8540.61
479_A482_R0.8520.61
253_I350_I0.8520.61
382_A386_E0.8490.61
300_Q341_R0.8420.60
310_L354_S0.8390.60
53_T56_E0.8390.60
49_A57_T0.8390.60
105_L143_Q0.8360.60
446_T449_V0.8350.60
78_M166_Q0.8320.59
480_E494_Y0.8320.59
245_F285_L0.8310.59
23_F360_V0.8310.59
248_N294_Q0.8300.59
195_H242_Q0.8300.59
216_A380_A0.8290.59
184_V196_P0.8270.59
8_T23_F0.8260.59
24_P31_R0.8240.59
64_L340_V0.8220.58
230_I277_A0.8180.58
129_S509_M0.8180.58
199_V226_V0.8170.58
295_S308_V0.8170.58
257_V317_L0.8150.58
467_A476_A0.8130.57
316_V356_A0.8080.57
437_E441_D0.8070.57
237_D241_P0.8000.56
78_M169_W0.8000.56
180_V197_I0.7990.56
462_L466_K0.7960.56
216_A411_E0.7960.56
294_Q423_V0.7950.56
98_E167_K0.7910.55
383_Y387_I0.7890.55
477_T482_R0.7890.55
135_A186_Y0.7870.55
375_E378_A0.7860.55
313_L356_A0.7840.55
52_G57_T0.7810.54
174_T177_L0.7790.54
416_A420_Q0.7780.54
25_G32_G0.7770.54
230_I275_Y0.7760.54
319_G362_P0.7760.54
472_D475_E0.7750.54
363_L368_A0.7730.54
291_T325_T0.7720.54
118_A147_P0.7720.54
219_L384_L0.7720.54
184_V242_Q0.7700.53
7_Y371_S0.7690.53
22_G265_R0.7690.53
215_L254_F0.7680.53
8_T11_D0.7670.53
265_R269_T0.7620.53
247_F285_L0.7620.53
463_S466_K0.7580.52
355_G358_D0.7580.52
376_I380_A0.7570.52
466_K481_L0.7570.52
4_D7_Y0.7550.52
184_V197_I0.7550.52
205_R211_A0.7530.52
254_F366_S0.7520.52
123_S154_T0.7510.52
54_A111_L0.7500.51
198_S246_F0.7490.51
467_A479_A0.7490.51
189_A473_A0.7480.51
27_F272_D0.7480.51
48_F168_E0.7480.51
477_T498_A0.7470.51
326_N330_E0.7450.51
293_G330_E0.7440.51
480_E483_A0.7430.51
497_A500_K0.7400.51
497_A501_A0.7390.50
25_G29_Y0.7360.50
88_H506_G0.7340.50
500_K503_A0.7340.50
229_A232_R0.7340.50
181_T185_E0.7340.50
164_I403_I0.7330.50
250_H292_A0.7320.50
240_A277_A0.7310.50
457_R462_L0.7300.50
269_T377_E0.7300.50
359_I368_A0.7260.49
105_L465_V0.7260.49
117_L122_T0.7250.49
447_L450_D0.7250.49
308_V326_N0.7210.49
125_T161_K0.7190.49
161_K203_H0.7190.49
226_V267_Y0.7170.48
33_V284_Q0.7150.48
217_F387_I0.7150.48
117_L144_Q0.7140.48
31_R364_G0.7140.48
271_M283_T0.7120.48
485_I491_T0.7120.48
461_R464_D0.7110.48
63_Y67_N0.7110.48
481_L512_F0.7100.48
501_A505_M0.7100.48
467_A473_A0.7100.48
60_R340_V0.7080.47
209_S248_N0.7080.47
180_V183_V0.7060.47
48_F78_M0.7050.47
316_V350_I0.7020.47
123_S153_G0.7010.47
254_F372_L0.7000.47
494_Y498_A0.6990.47
112_F115_I0.6990.47
171_V512_F0.6980.46
489_E493_P0.6970.46
246_F290_Q0.6960.46
98_E168_E0.6950.46
486_R515_E0.6940.46
327_S512_F0.6940.46
211_A313_L0.6940.46
341_R441_D0.6940.46
287_F320_S0.6930.46
159_M171_V0.6930.46
488_D494_Y0.6930.46
84_L90_M0.6920.46
180_V184_V0.6910.46
250_H256_E0.6890.46
423_V430_V0.6890.46
202_Y290_Q0.6860.45
23_F35_P0.6840.45
478_L481_L0.6830.45
204_I412_I0.6820.45
106_R465_V0.6820.45
135_A492_I0.6820.45
186_Y190_E0.6820.45
71_G154_T0.6800.45
61_F115_I0.6770.44
302_K305_I0.6730.44
474_V477_T0.6720.44
27_F283_T0.6710.44
470_D475_E0.6700.44
4_D12_V0.6700.44
456_D463_S0.6690.44
255_E300_Q0.6680.44
35_P284_Q0.6670.44
248_N259_K0.6660.43
76_F290_Q0.6660.43
34_Y360_V0.6660.43
46_R153_G0.6650.43
297_T430_V0.6640.43
42_T45_M0.6640.43
217_F399_V0.6630.43
37_G360_V0.6620.43
465_V479_A0.6610.43
35_P224_A0.6570.43
254_F362_P0.6560.43
219_L285_L0.6560.43
65_I115_I0.6560.43
81_L168_E0.6560.43
205_R250_H0.6550.42
161_K164_I0.6550.42
88_H513_K0.6530.42
178_D182_D0.6520.42
7_Y368_A0.6510.42
25_G31_R0.6500.42
266_I270_L0.6500.42
490_N495_I0.6490.42
226_V275_Y0.6470.42
252_A366_S0.6470.42
105_L108_M0.6470.42
64_L69_Q0.6460.42
73_S347_Q0.6450.41
3_V6_L0.6450.41
49_A61_F0.6440.41
105_L136_M0.6440.41
269_T272_D0.6390.41
469_R474_V0.6390.41
55_E113_D0.6350.41
106_R468_E0.6350.41
316_V351_A0.6350.41
381_M384_L0.6340.40
60_R63_Y0.6340.40
270_L519_Y0.6310.40
106_R197_I0.6300.40
223_F227_E0.6300.40
218_T285_L0.6290.40
35_P65_I0.6290.40
302_K306_A0.6290.40
212_V376_I0.6290.40
24_P253_I0.6290.40
473_A483_A0.6280.40
303_N426_G0.6280.40
296_L335_P0.6260.40
382_A430_V0.6260.40
226_V230_I0.6240.40
296_L311_Q0.6230.39
351_A357_A0.6220.39
55_E461_R0.6220.39
477_T481_L0.6210.39
460_G468_E0.6200.39
325_T347_Q0.6190.39
137_Y281_A0.6190.39
387_I431_V0.6180.39
109_E144_Q0.6170.39
288_H324_H0.6170.39
223_F277_A0.6160.39
293_G326_N0.6140.39
313_L427_E0.6130.39
64_L344_L0.6130.39
356_A466_K0.6120.38
142_D146_V0.6120.38
453_A460_G0.6110.38
153_G192_P0.6110.38
328_F358_D0.6080.38
34_Y425_D0.6070.38
455_R459_L0.6070.38
202_Y293_G0.6060.38
314_A349_I0.6040.38
300_Q441_D0.6040.38
204_I399_V0.6040.38
3_V359_I0.6030.38
478_L482_R0.6030.38
431_V435_E0.6030.38
238_A282_A0.6020.38
349_I431_V0.6010.37
256_E311_Q0.6000.37
309_T349_I0.6000.37
450_D453_A0.5970.37
331_A457_R0.5970.37
299_Q470_D0.5970.37
491_T512_F0.5970.37
488_D514_D0.5960.37
135_A139_A0.5960.37
236_V275_Y0.5950.37
59_E66_D0.5930.37
249_S314_A0.5910.37
152_R286_K0.5910.37
29_Y280_D0.5910.37
46_R154_T0.5910.37
43_W259_K0.5900.36
132_V508_I0.5900.36
158_D292_A0.5900.36
32_G364_G0.5890.36
350_I441_D0.5870.36
449_V455_R0.5870.36
211_A295_S0.5870.36
202_Y206_E0.5860.36
60_R64_L0.5860.36
139_A142_D0.5850.36
342_V516_F0.5810.36
206_E293_G0.5810.36
195_H286_K0.5810.36
164_I204_I0.5810.36
463_S482_R0.5800.36
161_K225_Y0.5800.36
485_I515_E0.5800.36
482_R519_Y0.5790.35
143_Q500_K0.5790.35
199_V218_T0.5790.35
185_E228_D0.5780.35
200_S326_N0.5780.35
312_A325_T0.5780.35
55_E89_R0.5760.35
125_T203_H0.5750.35
470_D478_L0.5750.35
178_D488_D0.5750.35
390_L411_E0.5740.35
88_H92_L0.5730.35
511_V514_D0.5720.35
419_Y423_V0.5720.35
253_I316_V0.5720.35
86_S462_L0.5720.35
184_V239_F0.5720.35
12_V486_R0.5710.35
317_L356_A0.5700.35
73_S290_Q0.5700.35
466_K470_D0.5700.35
219_L223_F0.5700.35
46_R73_S0.5700.35
302_K342_V0.5700.35
349_I429_T0.5690.35
278_E283_T0.5690.35
467_A486_R0.5690.35
251_N354_S0.5690.35
189_A486_R0.5680.35
438_M442_T0.5680.35
491_T495_I0.5680.35
46_R322_S0.5670.34
173_P176_S0.5660.34
223_F276_G0.5650.34
303_N438_M0.5640.34
230_I235_D0.5640.34
138_L430_V0.5640.34
48_F57_T0.5640.34
352_E428_E0.5630.34
65_I118_A0.5620.34
92_L459_L0.5610.34
281_A284_Q0.5610.34
489_E492_I0.5590.34
263_A287_F0.5580.34
178_D232_R0.5560.33
6_L359_I0.5550.33
184_V400_L0.5550.33
59_E63_Y0.5550.33
255_E372_L0.5550.33
250_H311_Q0.5550.33
374_N382_A0.5550.33
72_L76_F0.5540.33
251_N349_I0.5540.33
224_A399_V0.5520.33
458_Q461_R0.5520.33
390_L405_D0.5520.33
213_Q217_F0.5510.33
267_Y380_A0.5500.33
475_E482_R0.5500.33
238_A241_P0.5500.33
75_A125_T0.5500.33
407_Y410_R0.5500.33
127_N161_K0.5500.33
73_S123_S0.5500.33
80_S133_I0.5500.33
458_Q462_L0.5500.33
476_A479_A0.5490.33
182_D185_E0.5490.33
62_H113_D0.5490.33
404_A423_V0.5480.33
34_Y336_S0.5470.33
72_L125_T0.5460.33
378_A389_E0.5460.33
7_Y11_D0.5460.33
299_Q433_V0.5450.33
465_V468_E0.5450.33
355_G359_I0.5440.32
109_E140_L0.5440.32
300_Q342_V0.5430.32
211_A376_I0.5420.32
69_Q364_G0.5410.32
440_A443_S0.5410.32
456_D468_E0.5410.32
106_R143_Q0.5400.32
207_A347_Q0.5390.32
126_I130_A0.5390.32
75_A203_H0.5390.32
418_E421_S0.5390.32
81_L94_E0.5390.32
213_Q408_F0.5380.32
6_L24_P0.5370.32
204_I209_S0.5370.32
300_Q438_M0.5360.32
12_V367_F0.5360.32
459_L465_V0.5330.32
54_A331_A0.5330.32
368_A372_L0.5320.31
161_K166_Q0.5310.31
238_A448_H0.5310.31
59_E430_V0.5310.31
441_D520_Q0.5300.31
72_L154_T0.5290.31
57_T74_T0.5290.31
476_A480_E0.5260.31
106_R289_T0.5260.31
201_G221_D0.5260.31
135_A496_V0.5250.31
156_Q246_F0.5250.31
374_N475_E0.5250.31
198_S244_S0.5240.31
82_M518_G0.5230.31
79_P91_S0.5220.31
410_R430_V0.5220.31
200_S246_F0.5220.31
287_F290_Q0.5210.31
294_Q458_Q0.5210.31
200_S218_T0.5200.30
57_T335_P0.5200.30
236_V282_A0.5190.30
389_E472_D0.5190.30
300_Q344_L0.5180.30
117_L137_Y0.5180.30
266_I384_L0.5180.30
149_E272_D0.5170.30
105_L140_L0.5170.30
262_A369_V0.5170.30
460_G463_S0.5170.30
156_Q220_A0.5160.30
50_G330_E0.5160.30
466_K506_G0.5160.30
222_G245_F0.5160.30
453_A463_S0.5160.30
45_M351_A0.5150.30
364_G367_F0.5140.30
469_R472_D0.5140.30
310_L356_A0.5140.30
197_I229_A0.5130.30
137_Y147_P0.5120.30
201_G204_I0.5110.30
379_E428_E0.5100.30
62_H116_D0.5100.30
202_Y324_H0.5090.30
506_G510_A0.5090.30
420_Q461_R0.5090.30
405_D442_T0.5090.30
196_P199_V0.5090.30
483_A487_A0.5090.30
218_T325_T0.5080.29
52_G277_A0.5070.29
290_Q324_H0.5070.29
42_T436_H0.5050.29
48_F167_K0.5050.29
437_E463_S0.5050.29
212_V255_E0.5040.29
466_K504_T0.5040.29
269_T273_D0.5040.29
5_R441_D0.5040.29
309_T428_E0.5030.29
480_E489_E0.5030.29
343_A412_I0.5030.29
134_Y155_L0.5030.29
294_Q518_G0.5020.29
487_A515_E0.5020.29
50_G202_Y0.5020.29
457_R510_A0.5020.29
223_F399_V0.5020.29
249_S287_F0.5010.29
405_D410_R0.5010.29
50_G57_T0.5000.29
341_R519_Y0.5000.29
33_V411_E0.5000.29
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4r3uA 2 0.9753 100 0.052 Contact Map
2xijA 2 0.981 100 0.068 Contact Map
1reqA 1 0.9829 100 0.071 Contact Map
4xc8A 2 0.9639 100 0.111 Contact Map
1reqB 1 0.9125 100 0.226 Contact Map
3kp1A 2 0.8878 100 0.466 Contact Map
1ccwB 2 0.8365 100 0.784 Contact Map
3r12A 2 0.3612 38.9 0.981 Contact Map
2la2A 1 0.0646 32.7 0.982 Contact Map
1p8aA 1 0.2148 28 0.983 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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