Q9HRG8 - HALSA - GREMLIN Contacts

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Q9HRG8 - Uncharacterized protein

UniProt:	Q9HRG8	Sequences: MTTVWVLGNQLTRTAGPLTDDPDRVLLIEAAALARRRRYHPQKLCMVFAAMRHFRDELRDDGVDVVYERAETFGAGLDAYFDAHPGDDLVVQRPANHGTADRLRELVAARGGSLRVVANAQFRCSPAQFDDWMGTEPPFKHRPFYRHMRRETGYLMRDDDTPEGGDWSYDDQNQETPPAEYDSPSVGGFEYDEHVPAVRDWVATEFDTWGDPDGFDWPVTREQATRALESFVADRLAGFGPYEDAVLADDWHLEHSLLSAAVNIGLLHPEEVADAALDAYRSRDDIPLNSIEGFVRQLIGWREFMRHVYRHQMPGLATANQLGADRDLPPLYWTPTATDMACLGSAAGRVYDRGYAHHIERLMVLSNFALTYGARPQALTEWFHGGFVDAYDWVVTPNVVGMGSFGTDAFTSKPYASSANYIDKMTDHCSDCAFDPDSTVGERACPFNSLYWDFLATHEDTLRSNHRMGLVYSHLDSKRDAGKLAAIRERAQRVREGVAAGRL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	503 (490)
Sequences:	1057 (797)
Seq/√Len:	36.0

HALSA - Q9HRG8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
459_E	476_D	5.636	1.00
286_I	291_I	5.633	1.00
327_D	378_A	4.557	1.00
218_P	261_A	4.016	1.00
225_T	271_E	3.846	1.00
420_N	424_K	3.747	1.00
221_R	225_T	3.727	1.00
277_L	295_V	3.618	1.00
140_K	412_S	3.360	1.00
46_M	264_I	3.189	1.00
270_E	274_D	3.163	1.00
128_Q	151_E	3.103	1.00
273_A	299_I	3.051	1.00
419_A	436_P	2.913	1.00
453_D	457_T	2.883	1.00
475_L	484_L	2.852	1.00
339_D	433_A	2.815	1.00
47_V	391_Y	2.735	1.00
228_L	272_V	2.705	1.00
459_E	463_R	2.643	1.00
246_V	426_T	2.636	1.00
42_Q	217_W	2.614	1.00
232_V	279_A	2.599	1.00
221_R	271_E	2.550	1.00
326_R	495_R	2.546	1.00
34_A	48_F	2.544	1.00
175_E	241_P	2.526	1.00
354_G	388_V	2.455	1.00
349_R	353_R	2.453	1.00
341_A	345_S	2.453	1.00
343_L	347_A	2.443	1.00
229_E	275_A	2.432	1.00
241_P	290_S	2.399	1.00
156_M	159_D	2.371	1.00
456_A	488_R	2.332	0.99
332_Y	369_A	2.314	0.99
211_D	352_D	2.311	0.99
373_G	457_T	2.255	0.99
45_C	212_P	2.247	0.99
478_K	483_K	2.207	0.99
305_M	410_F	2.203	0.99
490_R	494_V	2.113	0.99
330_P	334_T	2.106	0.99
88_D	115_R	2.092	0.99
380_T	400_V	2.071	0.99
49_A	53_H	2.054	0.99
177_P	247_L	2.023	0.99
276_A	291_I	2.012	0.98
365_L	383_F	2.009	0.98
47_V	264_I	1.969	0.98
163_E	280_Y	1.969	0.98
73_F	99_T	1.961	0.98
438_S	443_R	1.958	0.98
156_M	160_D	1.952	0.98
278_D	282_S	1.948	0.98
45_C	199_R	1.934	0.98
53_H	219_V	1.931	0.98
453_D	492_Q	1.920	0.98
473_S	476_D	1.903	0.98
44_L	208_T	1.897	0.98
123_R	152_T	1.883	0.98
53_H	220_T	1.863	0.97
455_L	468_M	1.860	0.97
304_F	410_F	1.855	0.97
453_D	488_R	1.849	0.97
458_H	462_L	1.849	0.97
251_W	353_R	1.843	0.97
142_R	168_S	1.841	0.97
435_D	438_S	1.807	0.97
166_D	169_Y	1.799	0.97
246_V	428_H	1.792	0.97
93_R	126_P	1.789	0.97
19_T	120_A	1.781	0.97
13_R	57_E	1.751	0.96
163_E	281_R	1.746	0.96
332_Y	374_A	1.727	0.96
100_A	126_P	1.695	0.95
332_Y	365_L	1.695	0.95
90_V	117_V	1.667	0.95
77_L	106_L	1.646	0.95
475_L	488_R	1.632	0.94
366_S	403_G	1.629	0.94
324_A	416_A	1.624	0.94
66_V	83_A	1.598	0.94
16_G	120_A	1.598	0.94
49_A	194_H	1.593	0.94
209_W	351_Y	1.587	0.94
423_D	430_S	1.583	0.93
51_M	67_Y	1.577	0.93
5_W	99_T	1.576	0.93
317_A	396_T	1.569	0.93
470_L	473_S	1.569	0.93
453_D	495_R	1.568	0.93
154_Y	273_A	1.559	0.93
229_E	233_A	1.550	0.93
123_R	270_E	1.548	0.93
277_L	281_R	1.539	0.92
8_G	51_M	1.539	0.92
379_L	404_S	1.534	0.92
224_A	261_A	1.533	0.92
318_T	377_Q	1.532	0.92
24_R	66_V	1.502	0.92
334_T	337_A	1.494	0.91
483_K	487_I	1.492	0.91
209_W	386_G	1.490	0.91
439_T	483_K	1.489	0.91
249_D	345_S	1.487	0.91
462_L	468_M	1.486	0.91
324_A	417_S	1.473	0.91
321_Q	461_T	1.470	0.91
433_A	443_R	1.459	0.90
230_S	235_R	1.458	0.90
488_R	492_Q	1.457	0.90
441_G	490_R	1.433	0.89
241_P	289_N	1.413	0.89
365_L	399_V	1.408	0.89
274_D	277_L	1.408	0.89
422_I	426_T	1.406	0.89
217_W	257_L	1.403	0.88
373_G	453_D	1.391	0.88
66_V	84_H	1.388	0.88
322_L	462_L	1.378	0.88
101_D	104_R	1.358	0.87
123_R	268_H	1.355	0.87
177_P	181_Y	1.354	0.87
440_V	490_R	1.346	0.86
365_L	386_G	1.343	0.86
81_F	86_G	1.333	0.86
195_V	219_V	1.330	0.86
372_Y	495_R	1.327	0.85
305_M	397_P	1.327	0.85
133_M	139_F	1.321	0.85
383_F	399_V	1.316	0.85
264_I	391_Y	1.308	0.85
247_L	427_D	1.307	0.85
449_S	490_R	1.299	0.84
76_G	79_A	1.298	0.84
158_D	163_E	1.296	0.84
154_Y	299_I	1.294	0.84
435_D	443_R	1.290	0.84
35_R	208_T	1.289	0.84
189_F	227_A	1.286	0.84
123_R	299_I	1.280	0.83
346_A	428_H	1.270	0.83
192_D	195_V	1.266	0.83
27_L	67_Y	1.266	0.83
26_L	80_Y	1.264	0.83
39_Y	43_K	1.264	0.83
364_V	422_I	1.247	0.82
138_P	143_P	1.247	0.82
455_L	471_V	1.247	0.82
100_A	104_R	1.239	0.81
154_Y	277_L	1.237	0.81
380_T	404_S	1.235	0.81
223_Q	226_R	1.233	0.81
3_T	86_G	1.231	0.81
49_A	198_V	1.227	0.81
322_L	461_T	1.226	0.81
32_A	102_R	1.223	0.80
468_M	471_V	1.223	0.80
28_I	76_G	1.214	0.80
249_D	427_D	1.210	0.80
317_A	392_D	1.208	0.80
181_Y	254_E	1.203	0.79
291_I	295_V	1.199	0.79
228_L	232_V	1.197	0.79
124_C	148_M	1.192	0.79
422_I	447_F	1.189	0.78
88_D	113_S	1.186	0.78
347_A	365_L	1.183	0.78
57_E	221_R	1.182	0.78
331_L	347_A	1.176	0.78
456_A	484_L	1.169	0.77
36_R	39_Y	1.169	0.77
439_T	478_K	1.164	0.77
70_A	201_W	1.163	0.77
380_T	403_G	1.162	0.77
56_D	59_R	1.162	0.77
138_P	412_S	1.161	0.77
137_P	166_D	1.160	0.77
470_L	474_H	1.159	0.77
53_H	194_H	1.154	0.76
252_H	353_R	1.154	0.76
26_L	77_L	1.153	0.76
404_S	417_S	1.153	0.76
94_P	100_A	1.152	0.76
366_S	404_S	1.148	0.76
36_R	96_N	1.143	0.76
449_S	494_V	1.142	0.76
123_R	273_A	1.142	0.76
308_V	410_F	1.138	0.75
230_S	234_D	1.137	0.75
68_E	76_G	1.136	0.75
121_Q	265_G	1.136	0.75
341_A	431_D	1.136	0.75
228_L	271_E	1.118	0.74
72_T	75_A	1.115	0.74
375_R	378_A	1.113	0.74
28_I	73_F	1.107	0.73
469_G	473_S	1.102	0.73
152_T	299_I	1.102	0.73
41_P	212_P	1.097	0.73
356_A	387_F	1.094	0.72
462_L	465_N	1.086	0.72
420_N	439_T	1.075	0.71
474_H	477_S	1.075	0.71
463_R	476_D	1.072	0.71
377_Q	400_V	1.070	0.71
341_A	344_G	1.065	0.70
93_R	100_A	1.064	0.70
485_A	489_E	1.063	0.70
228_L	258_L	1.062	0.70
324_A	458_H	1.059	0.70
335_P	344_G	1.058	0.70
92_Q	119_N	1.054	0.70
46_M	215_F	1.053	0.69
423_D	436_P	1.050	0.69
252_H	257_L	1.046	0.69
308_V	316_L	1.046	0.69
243_E	355_Y	1.045	0.69
370_L	404_S	1.045	0.69
275_A	279_A	1.044	0.69
43_K	448_N	1.043	0.69
73_F	102_R	1.040	0.68
57_E	222_E	1.039	0.68
38_R	385_G	1.034	0.68
248_A	428_H	1.033	0.68
59_R	64_D	1.032	0.68
45_C	215_F	1.031	0.68
177_P	253_L	1.031	0.68
453_D	456_A	1.031	0.68
456_A	459_E	1.029	0.68
371_T	416_A	1.015	0.67
46_M	261_A	1.014	0.66
374_A	404_S	1.012	0.66
384_H	395_V	1.011	0.66
325_D	375_R	1.009	0.66
203_A	213_D	1.008	0.66
344_G	348_G	1.006	0.66
15_A	92_Q	1.006	0.66
365_L	369_A	1.004	0.66
36_R	98_G	1.003	0.66
271_E	275_A	1.002	0.66
20_D	117_V	1.000	0.65
166_D	172_Q	0.995	0.65
71_E	200_D	0.995	0.65
282_S	479_R	0.994	0.65
202_V	206_F	0.993	0.65
316_L	319_A	0.991	0.65
455_L	472_Y	0.990	0.65
449_S	487_I	0.987	0.64
257_L	260_A	0.985	0.64
341_A	428_H	0.984	0.64
97_H	314_P	0.977	0.64
251_W	348_G	0.977	0.64
468_M	472_Y	0.976	0.63
458_H	468_M	0.972	0.63
270_E	277_L	0.970	0.63
276_A	294_F	0.968	0.63
118_A	127_A	0.968	0.63
91_V	103_L	0.967	0.63
334_T	347_A	0.965	0.63
396_T	410_F	0.963	0.62
41_P	203_A	0.962	0.62
350_V	386_G	0.957	0.62
279_A	285_D	0.956	0.62
18_L	265_G	0.953	0.62
4_V	17_P	0.951	0.61
8_G	47_V	0.949	0.61
172_Q	175_E	0.943	0.61
369_A	374_A	0.940	0.61
31_A	35_R	0.938	0.60
31_A	205_E	0.937	0.60
349_R	360_E	0.935	0.60
232_V	295_V	0.930	0.60
225_T	275_A	0.929	0.60
93_R	116_V	0.929	0.60
176_T	304_F	0.929	0.60
287_P	290_S	0.928	0.60
217_W	388_V	0.928	0.60
383_F	395_V	0.926	0.59
339_D	434_F	0.926	0.59
308_V	411_T	0.925	0.59
248_A	345_S	0.923	0.59
89_L	110_R	0.922	0.59
53_H	195_V	0.920	0.59
13_R	61_D	0.919	0.59
5_W	28_I	0.912	0.58
228_L	275_A	0.911	0.58
5_W	89_L	0.910	0.58
16_G	92_Q	0.909	0.58
4_V	25_V	0.907	0.58
480_D	484_L	0.906	0.58
438_S	441_G	0.906	0.58
479_R	483_K	0.906	0.58
97_H	313_M	0.903	0.57
152_T	273_A	0.903	0.57
143_P	412_S	0.903	0.57
198_V	201_W	0.901	0.57
58_L	65_V	0.900	0.57
96_N	392_D	0.900	0.57
74_G	106_L	0.898	0.57
466_H	469_G	0.897	0.57
248_A	341_A	0.896	0.57
74_G	99_T	0.895	0.57
237_A	276_A	0.895	0.57
6_V	25_V	0.893	0.57
107_V	114_L	0.893	0.57
350_V	387_F	0.889	0.56
129_F	133_M	0.884	0.56
258_L	264_I	0.883	0.56
43_K	367_N	0.882	0.56
178_P	181_Y	0.880	0.55
238_G	241_P	0.878	0.55
417_S	447_F	0.878	0.55
348_G	352_D	0.877	0.55
248_A	427_D	0.876	0.55
153_G	156_M	0.872	0.55
129_F	132_W	0.872	0.55
280_Y	291_I	0.872	0.55
368_F	372_Y	0.870	0.55
152_T	270_E	0.868	0.54
490_R	493_R	0.867	0.54
154_Y	274_D	0.864	0.54
136_E	143_P	0.862	0.54
44_L	206_F	0.857	0.53
81_F	89_L	0.856	0.53
331_L	334_T	0.853	0.53
41_P	198_V	0.853	0.53
42_Q	214_G	0.852	0.53
163_E	169_Y	0.851	0.53
6_V	17_P	0.848	0.53
140_K	466_H	0.847	0.53
191_Y	223_Q	0.845	0.52
238_G	254_E	0.845	0.52
139_F	311_H	0.843	0.52
156_M	163_E	0.842	0.52
407_T	411_T	0.841	0.52
439_T	449_S	0.838	0.52
493_R	497_G	0.836	0.52
140_K	143_P	0.836	0.52
335_P	348_G	0.836	0.52
59_R	69_R	0.836	0.52
152_T	156_M	0.835	0.52
43_K	391_Y	0.833	0.51
232_V	236_L	0.833	0.51
38_R	208_T	0.830	0.51
56_D	194_H	0.829	0.51
155_L	288_L	0.828	0.51
201_W	205_E	0.828	0.51
258_L	262_V	0.827	0.51
276_A	295_V	0.827	0.51
23_D	90_V	0.825	0.51
484_L	488_R	0.824	0.51
286_I	290_S	0.824	0.51
265_G	391_Y	0.824	0.51
41_P	208_T	0.822	0.50
169_Y	289_N	0.819	0.50
374_A	379_L	0.817	0.50
330_P	378_A	0.815	0.50
144_F	148_M	0.812	0.50
154_Y	295_V	0.811	0.49
329_P	332_Y	0.810	0.49
220_T	223_Q	0.808	0.49
225_T	268_H	0.800	0.49
164_G	288_L	0.799	0.48
377_Q	380_T	0.791	0.48
49_A	220_T	0.791	0.48
316_L	407_T	0.787	0.47
187_G	230_S	0.787	0.47
258_L	298_L	0.787	0.47
443_R	490_R	0.785	0.47
199_R	203_A	0.781	0.47
6_V	15_A	0.776	0.46
81_F	84_H	0.776	0.46
141_H	256_S	0.776	0.46
471_V	474_H	0.774	0.46
369_A	379_L	0.773	0.46
243_E	256_S	0.771	0.46
282_S	285_D	0.771	0.46
4_V	90_V	0.771	0.46
396_T	400_V	0.771	0.46
436_P	448_N	0.770	0.46
492_Q	496_E	0.769	0.46
216_D	353_R	0.769	0.46
148_M	299_I	0.768	0.46
419_A	448_N	0.767	0.46
218_P	260_A	0.766	0.46
225_T	232_V	0.764	0.45
53_H	192_D	0.764	0.45
130_D	311_H	0.762	0.45
169_Y	288_L	0.760	0.45
81_F	112_G	0.760	0.45
141_H	148_M	0.760	0.45
313_M	396_T	0.758	0.45
478_K	487_I	0.754	0.45
74_G	77_L	0.753	0.44
147_H	150_R	0.752	0.44
177_P	183_S	0.749	0.44
195_V	215_F	0.749	0.44
470_L	477_S	0.747	0.44
177_P	182_D	0.743	0.44
429_C	446_P	0.742	0.43
89_L	112_G	0.741	0.43
26_L	410_F	0.741	0.43
103_L	106_L	0.740	0.43
93_R	118_A	0.737	0.43
52_R	67_Y	0.736	0.43
332_Y	343_L	0.735	0.43
456_A	475_L	0.733	0.43
160_D	479_R	0.732	0.43
17_P	25_V	0.729	0.42
246_V	364_V	0.727	0.42
371_T	450_L	0.726	0.42
33_L	384_H	0.726	0.42
429_C	445_C	0.726	0.42
228_L	268_H	0.725	0.42
8_G	27_L	0.725	0.42
229_E	278_D	0.720	0.42
356_A	360_E	0.720	0.42
211_D	214_G	0.719	0.42
384_H	392_D	0.718	0.41
148_M	152_T	0.718	0.41
74_G	102_R	0.718	0.41
133_M	311_H	0.718	0.41
224_A	227_A	0.718	0.41
474_H	478_K	0.718	0.41
46_M	260_A	0.717	0.41
225_T	228_L	0.717	0.41
345_S	349_R	0.717	0.41
172_Q	418_S	0.716	0.41
455_L	469_G	0.715	0.41
91_V	116_V	0.713	0.41
85_P	477_S	0.712	0.41
177_P	180_E	0.710	0.41
324_A	392_D	0.708	0.41
33_L	98_G	0.706	0.40
440_V	483_K	0.706	0.40
219_V	223_Q	0.705	0.40
66_V	80_Y	0.703	0.40
25_V	58_L	0.695	0.40
331_L	468_M	0.695	0.40
34_A	206_F	0.694	0.39
339_D	443_R	0.694	0.39
128_Q	152_T	0.691	0.39
49_A	195_V	0.690	0.39
431_D	439_T	0.690	0.39
342_C	429_C	0.689	0.39
183_S	254_E	0.687	0.39
123_R	151_E	0.687	0.39
49_A	219_V	0.686	0.39
405_F	462_L	0.685	0.39
144_F	290_S	0.684	0.39
264_I	388_V	0.682	0.38
38_R	41_P	0.682	0.38
80_Y	84_H	0.682	0.38
12_T	15_A	0.681	0.38
43_K	449_S	0.681	0.38
57_E	61_D	0.678	0.38
243_E	418_S	0.677	0.38
278_D	476_D	0.676	0.38
44_L	47_V	0.675	0.38
75_A	79_A	0.674	0.38
42_Q	216_D	0.670	0.37
72_T	76_G	0.668	0.37
423_D	437_D	0.667	0.37
73_F	103_L	0.667	0.37
16_G	117_V	0.664	0.37
142_R	146_R	0.663	0.37
272_V	299_I	0.663	0.37
439_T	490_R	0.662	0.37
276_A	279_A	0.659	0.37
224_A	266_L	0.658	0.36
342_C	446_P	0.658	0.36
424_K	473_S	0.658	0.36
39_Y	391_Y	0.657	0.36
333_W	390_A	0.657	0.36
183_S	250_D	0.655	0.36
166_D	229_E	0.655	0.36
39_Y	383_F	0.654	0.36
55_R	169_Y	0.654	0.36
435_D	441_G	0.654	0.36
403_G	410_F	0.653	0.36
191_Y	215_F	0.653	0.36
24_R	86_G	0.652	0.36
247_L	250_D	0.650	0.36
99_T	391_Y	0.650	0.36
129_F	307_H	0.649	0.36
222_E	229_E	0.648	0.36
331_L	447_F	0.647	0.36
269_P	298_L	0.647	0.36
49_A	52_R	0.646	0.36
34_A	39_Y	0.646	0.36
220_T	266_L	0.646	0.36
12_T	120_A	0.645	0.35
217_W	261_A	0.644	0.35
40_H	43_K	0.643	0.35
221_R	268_H	0.643	0.35
260_A	405_F	0.642	0.35
370_L	416_A	0.642	0.35
386_G	395_V	0.642	0.35
403_G	417_S	0.641	0.35
339_D	424_K	0.638	0.35
342_C	445_C	0.637	0.35
366_S	370_L	0.636	0.35
310_R	313_M	0.636	0.35
177_P	427_D	0.634	0.35
33_L	39_Y	0.633	0.34
150_R	160_D	0.633	0.34
250_D	253_L	0.633	0.34
48_F	264_I	0.633	0.34
329_P	368_F	0.632	0.34
380_T	385_G	0.632	0.34
36_R	43_K	0.630	0.34
20_D	63_V	0.629	0.34
392_D	395_V	0.629	0.34
196_P	213_D	0.629	0.34
161_T	166_D	0.626	0.34
321_Q	462_L	0.626	0.34
254_E	313_M	0.624	0.34
331_L	335_P	0.622	0.34
38_R	207_D	0.620	0.33
55_R	59_R	0.619	0.33
321_Q	405_F	0.618	0.33
381_E	385_G	0.618	0.33
417_S	424_K	0.618	0.33
80_Y	86_G	0.617	0.33
90_V	115_R	0.617	0.33
131_D	431_D	0.615	0.33
33_L	36_R	0.615	0.33
18_L	25_V	0.615	0.33
7_L	39_Y	0.613	0.33
19_T	337_A	0.613	0.33
33_L	95_A	0.613	0.33
87_D	460_D	0.612	0.33
304_F	471_V	0.609	0.33
154_Y	270_E	0.609	0.33
367_N	416_A	0.608	0.33
39_Y	448_N	0.608	0.33
134_G	442_E	0.608	0.33
36_R	350_V	0.608	0.33
276_A	286_I	0.607	0.32
4_V	400_V	0.606	0.32
129_F	139_F	0.605	0.32
304_F	462_L	0.605	0.32
335_P	351_Y	0.604	0.32
42_Q	353_R	0.603	0.32
134_G	311_H	0.603	0.32
150_R	494_V	0.602	0.32
405_F	479_R	0.601	0.32
49_A	223_Q	0.600	0.32
44_L	201_W	0.600	0.32
139_F	312_Q	0.600	0.32
236_L	276_A	0.597	0.32
420_N	423_D	0.597	0.32
448_N	471_V	0.597	0.32
179_A	254_E	0.596	0.32
252_H	355_Y	0.596	0.32
439_T	487_I	0.595	0.32
43_K	471_V	0.595	0.32
191_Y	227_A	0.593	0.31
281_R	291_I	0.592	0.31
356_A	428_H	0.592	0.31
62_G	258_L	0.592	0.31
217_W	260_A	0.590	0.31
243_E	308_V	0.589	0.31
462_L	472_Y	0.588	0.31
254_E	257_L	0.587	0.31
256_S	259_S	0.587	0.31
33_L	395_V	0.586	0.31
268_H	274_D	0.584	0.31
176_T	470_L	0.584	0.31
182_D	254_E	0.583	0.31
161_T	354_G	0.583	0.31
222_E	496_E	0.581	0.31
217_W	242_Y	0.581	0.31
189_F	223_Q	0.580	0.30
404_S	420_N	0.577	0.30
433_A	436_P	0.577	0.30
191_Y	195_V	0.576	0.30
251_W	349_R	0.576	0.30
188_G	216_D	0.575	0.30
226_R	305_M	0.575	0.30
101_D	105_E	0.575	0.30
237_A	290_S	0.575	0.30
134_G	412_S	0.574	0.30
248_A	431_D	0.573	0.30
31_A	34_A	0.573	0.30
197_A	201_W	0.573	0.30
442_E	490_R	0.573	0.30
81_F	85_P	0.572	0.30
268_H	271_E	0.572	0.30
21_D	323_G	0.571	0.30
400_V	404_S	0.570	0.30
153_G	464_S	0.570	0.30
429_C	444_A	0.569	0.30
227_A	235_R	0.569	0.30
6_V	131_D	0.569	0.30
169_Y	220_T	0.569	0.30
232_V	276_A	0.568	0.30
364_V	496_E	0.568	0.30
178_P	242_Y	0.567	0.30
392_D	396_T	0.567	0.30
39_Y	384_H	0.567	0.30
453_D	491_A	0.567	0.30
317_A	380_T	0.563	0.29
276_A	460_D	0.563	0.29
34_A	44_L	0.563	0.29
46_M	354_G	0.562	0.29
449_S	471_V	0.562	0.29
186_V	189_F	0.562	0.29
27_L	169_Y	0.561	0.29
82_D	151_E	0.560	0.29
217_W	221_R	0.559	0.29
392_D	405_F	0.557	0.29
96_N	99_T	0.556	0.29
56_D	82_D	0.556	0.29
419_A	455_L	0.556	0.29
115_R	274_D	0.555	0.29
103_L	116_V	0.554	0.29
449_S	475_L	0.554	0.29
9_N	168_S	0.553	0.29
194_H	197_A	0.553	0.29
42_Q	260_A	0.552	0.28
340_M	372_Y	0.552	0.28
254_E	439_T	0.551	0.28
304_F	411_T	0.551	0.28
438_S	444_A	0.550	0.28
187_G	227_A	0.550	0.28
346_A	365_L	0.550	0.28
285_D	323_G	0.549	0.28
37_R	98_G	0.548	0.28
4_V	63_V	0.548	0.28
276_A	298_L	0.546	0.28
81_F	110_R	0.544	0.28
88_D	109_A	0.544	0.28
35_R	41_P	0.544	0.28
274_D	348_G	0.544	0.28
186_V	191_Y	0.543	0.28
23_D	63_V	0.543	0.28
105_E	233_A	0.543	0.28
78_D	82_D	0.543	0.28
39_Y	395_V	0.540	0.28
8_G	67_Y	0.540	0.28
46_M	218_P	0.540	0.28
8_G	48_F	0.540	0.28
177_P	254_E	0.540	0.28
68_E	75_A	0.539	0.28
339_D	438_S	0.539	0.28
96_N	384_H	0.539	0.28
127_A	131_D	0.539	0.28
304_F	308_V	0.539	0.28
227_A	322_L	0.538	0.27
207_D	211_D	0.538	0.27
44_L	384_H	0.538	0.27
387_F	465_N	0.537	0.27
100_A	116_V	0.537	0.27
37_R	384_H	0.535	0.27
77_L	103_L	0.535	0.27
431_D	438_S	0.534	0.27
146_R	445_C	0.534	0.27
38_R	209_W	0.534	0.27
316_L	411_T	0.533	0.27
313_M	317_A	0.533	0.27
223_Q	458_H	0.532	0.27
6_V	24_R	0.532	0.27
176_T	247_L	0.530	0.27
96_N	395_V	0.530	0.27
328_L	374_A	0.530	0.27
18_L	92_Q	0.529	0.27
350_V	365_L	0.529	0.27
61_D	220_T	0.529	0.27
36_R	48_F	0.529	0.27
343_L	346_A	0.529	0.27
199_R	212_P	0.528	0.27
27_L	51_M	0.528	0.27
30_A	76_G	0.527	0.27
59_R	489_E	0.526	0.27
237_A	284_D	0.526	0.27
218_P	227_A	0.523	0.26
106_L	114_L	0.523	0.26
6_V	481_A	0.522	0.26
91_V	311_H	0.522	0.26
87_D	364_V	0.522	0.26
192_D	451_Y	0.520	0.26
178_P	230_S	0.520	0.26
59_R	172_Q	0.520	0.26
232_V	275_A	0.519	0.26
124_C	152_T	0.519	0.26
103_L	223_Q	0.519	0.26
400_V	403_G	0.519	0.26
221_R	439_T	0.518	0.26
28_I	36_R	0.517	0.26
9_N	310_R	0.517	0.26
12_T	265_G	0.517	0.26
305_M	369_A	0.517	0.26
367_N	448_N	0.517	0.26
483_K	486_A	0.516	0.26
375_R	379_L	0.516	0.26
343_L	447_F	0.516	0.26
18_L	46_M	0.516	0.26
24_R	64_D	0.516	0.26
137_P	478_K	0.516	0.26
202_V	205_E	0.515	0.26
197_A	206_F	0.515	0.26
365_L	374_A	0.515	0.26
78_D	109_A	0.514	0.26
15_A	120_A	0.514	0.26
305_M	471_V	0.514	0.26
15_A	121_Q	0.513	0.26
424_K	474_H	0.513	0.26
135_T	308_V	0.513	0.26
201_W	364_V	0.512	0.26
460_D	463_R	0.512	0.26
165_G	169_Y	0.512	0.26
180_E	492_Q	0.511	0.26
390_A	429_C	0.511	0.26
95_A	119_N	0.511	0.26
405_F	468_M	0.510	0.26
462_L	469_G	0.510	0.26
159_D	166_D	0.509	0.25
98_G	384_H	0.508	0.25
232_V	298_L	0.508	0.25
315_G	375_R	0.507	0.25
187_G	235_R	0.507	0.25
412_S	466_H	0.507	0.25
86_G	112_G	0.506	0.25
381_E	403_G	0.506	0.25
335_P	424_K	0.505	0.25
455_L	476_D	0.504	0.25
131_D	207_D	0.502	0.25
8_G	34_A	0.501	0.25
176_T	256_S	0.500	0.25
71_E	201_W	0.500	0.25
345_S	428_H	0.500	0.25

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4djaA	1	0.9861	100	0.456	Contact Map
3zxsA	1	0.9841	100	0.466	Contact Map
2wq7A	1	0.8986	100	0.679	Contact Map
4k0rA	1	0.833	100	0.738	Contact Map
4u63A	1	0.8767	100	0.738	Contact Map
4mlpC	1	0.9185	100	0.743	Contact Map
1owlA	1	0.8728	100	0.744	Contact Map
1u3dA	1	0.8628	100	0.744	Contact Map
1dnpA	1	0.8688	100	0.749	Contact Map
1np7A	1	0.8728	100	0.75	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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