THIC - HALSA - GREMLIN Contacts

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THIC - Phosphomethylpyrimidine synthase

UniProt:	Q9HRG2	Sequences: MSTQLQHARDGTVTDAMRRVADREGRDPEVVREAVADGHAVIPANHHHDALDPMIIGRDFATKVNANIGNSDTTGDIDDELEKLHTAVHYGADTVMDLSTGENLDGIRTANIDNSPVPVGTVPIYEAVTRVEDVTDITPDLLIDVVEKQAKQGVDYMTLHAGVLAEHLPLTDDRTTGIVSRGGSILSQWMTEHGEQNPLYTHYDELCEILQAHDVTISLGDGLRPGSVADASDDAQFAELDTLGELTRRAWDHGVQAMVEGPGHVPMDQIRANVDRQQEVCDGAPFYVLGPLVTDIAPGYDHITSAIGATEAARAGAAMLCYVTPKEHLGLPDAEDVRDGMAAYRIAAHAGDVAAGKPGARDWDDALSEARYNFDWNRQFDLALDPERAQAFHDQTLPGDNYKDARFCSMCGVDFCSMRIDQDARDAGDDADDMTELTTETDLSESAAAEVNRPPTGTHDAPAAEQAPSPGDDDDD	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	476 (419)
Sequences:	1236 (400)
Seq/√Len:	19.5

ECOLI - THIC
BACSU - THIC
HALSA - THIC
SULSO - THIC2 THIC1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
105_D	148_K	3.822	1.00
377_N	390_Q	3.751	1.00
62_T	355_A	3.384	1.00
247_T	251_W	3.299	1.00
55_I	60_F	3.264	1.00
378_R	381_D	3.239	1.00
247_T	259_V	3.141	0.99
34_A	40_A	3.117	0.99
143_I	205_E	3.071	0.99
293_V	350_A	2.998	0.99
84_L	95_V	2.992	0.99
271_R	275_D	2.990	0.99
176_T	418_M	2.978	0.99
339_D	388_R	2.975	0.99
20_V	55_I	2.865	0.99
176_T	227_S	2.814	0.99
35_V	42_I	2.739	0.98
15_D	18_R	2.728	0.98
146_V	199_L	2.711	0.98
210_L	217_I	2.685	0.98
29_E	32_R	2.648	0.98
143_I	206_L	2.572	0.98
208_E	253_H	2.536	0.97
150_A	215_V	2.518	0.97
26_R	31_V	2.515	0.97
109_T	152_Q	2.455	0.97
147_E	151_K	2.439	0.97
13_V	32_R	2.402	0.96
105_D	126_E	2.390	0.96
309_A	320_L	2.341	0.96
366_A	378_R	2.339	0.96
6_Q	211_Q	2.299	0.95
178_I	187_S	2.205	0.94
274_V	315_A	2.193	0.94
18_R	22_D	2.175	0.94
76_D	79_D	2.167	0.93
14_T	17_M	2.159	0.93
66_A	341_M	2.154	0.93
20_V	42_I	2.137	0.93
267_M	310_T	2.135	0.93
345_R	363_W	2.109	0.92
349_H	364_D	2.105	0.92
39_H	58_R	2.104	0.92
28_P	32_R	2.099	0.92
147_E	212_A	2.088	0.92
23_R	52_D	2.086	0.92
211_Q	253_H	2.083	0.92
30_V	34_A	2.076	0.92
296_I	363_W	2.069	0.92
31_V	40_A	2.055	0.91
248_R	282_D	2.042	0.91
39_H	283_G	2.004	0.90
298_P	304_T	2.003	0.90
121_T	154_V	1.981	0.90
204_D	249_R	1.968	0.90
159_L	217_I	1.946	0.89
267_M	311_E	1.928	0.89
232_S	273_N	1.926	0.89
82_E	334_A	1.913	0.88
103_N	106_G	1.909	0.88
146_V	206_L	1.902	0.88
82_E	85_H	1.829	0.86
211_Q	254_G	1.799	0.85
31_V	34_A	1.775	0.84
4_Q	17_M	1.765	0.84
361_R	365_D	1.758	0.83
40_A	60_F	1.753	0.83
175_T	365_D	1.738	0.83
150_A	157_M	1.728	0.82
251_W	282_D	1.709	0.82
391_A	395_Q	1.686	0.81
34_A	39_H	1.683	0.81
268_D	356_G	1.658	0.79
88_V	116_P	1.651	0.79
18_R	28_P	1.634	0.78
175_T	229_A	1.618	0.78
207_C	217_I	1.613	0.78
5_L	41_V	1.610	0.77
6_Q	254_G	1.610	0.77
369_E	373_N	1.599	0.77
305_S	323_V	1.586	0.76
259_V	277_Q	1.576	0.76
195_E	201_T	1.575	0.76
165_A	194_G	1.555	0.75
200_Y	245_E	1.553	0.75
159_L	206_L	1.551	0.75
269_Q	279_E	1.551	0.75
277_Q	286_F	1.538	0.74
62_T	357_K	1.531	0.74
4_Q	14_T	1.523	0.73
44_A	51_L	1.522	0.73
322_Y	337_V	1.513	0.73
240_L	286_F	1.498	0.72
175_T	227_S	1.497	0.72
13_V	28_P	1.492	0.72
232_S	286_F	1.488	0.71
370_A	378_R	1.488	0.71
273_N	286_F	1.487	0.71
67_N	158_T	1.471	0.71
219_L	243_L	1.465	0.70
277_Q	281_C	1.451	0.69
94_T	118_P	1.449	0.69
338_R	342_A	1.448	0.69
10_D	254_G	1.444	0.69
33_E	37_D	1.440	0.69
202_H	205_E	1.411	0.67
68_I	84_L	1.411	0.67
85_H	114_N	1.408	0.67
42_I	55_I	1.402	0.67
378_R	382_L	1.391	0.66
366_A	382_L	1.382	0.66
41_V	216_T	1.382	0.66
66_A	87_A	1.367	0.65
139_P	202_H	1.347	0.64
147_E	205_E	1.345	0.63
242_T	245_E	1.343	0.63
5_L	251_W	1.342	0.63
43_P	56_I	1.336	0.63
209_I	215_V	1.324	0.62
227_S	368_S	1.323	0.62
228_V	353_V	1.321	0.62
375_D	378_R	1.315	0.62
313_A	351_G	1.314	0.62
41_V	258_M	1.311	0.61
368_S	418_M	1.311	0.61
84_L	115_S	1.309	0.61
309_A	344_Y	1.296	0.60
139_P	201_T	1.292	0.60
89_H	387_E	1.286	0.60
8_A	14_T	1.282	0.60
81_L	84_L	1.280	0.60
31_V	35_V	1.271	0.59
396_T	409_S	1.267	0.59
271_R	315_A	1.259	0.58
102_E	107_I	1.257	0.58
278_Q	318_A	1.256	0.58
17_M	31_V	1.253	0.58
112_I	149_Q	1.253	0.58
87_A	341_M	1.251	0.58
59_D	318_A	1.244	0.57
338_R	388_R	1.237	0.57
251_W	259_V	1.234	0.57
167_H	242_T	1.233	0.57
268_D	361_R	1.229	0.56
274_V	317_A	1.223	0.56
232_S	237_F	1.215	0.55
7_H	12_T	1.204	0.55
203_Y	219_L	1.204	0.55
365_D	369_E	1.201	0.55
207_C	253_H	1.200	0.54
207_C	255_V	1.197	0.54
104_L	107_I	1.188	0.54
142_L	146_V	1.187	0.54
58_R	283_G	1.184	0.53
20_V	35_V	1.183	0.53
156_Y	319_M	1.181	0.53
105_D	152_Q	1.179	0.53
294_T	297_A	1.175	0.53
359_G	362_D	1.173	0.53
126_E	130_R	1.163	0.52
166_E	196_Q	1.159	0.52
30_V	40_A	1.158	0.52
251_W	284_A	1.157	0.52
26_R	30_V	1.153	0.51
237_F	276_R	1.152	0.51
149_Q	157_M	1.143	0.51
66_A	95_V	1.139	0.51
170_L	238_A	1.136	0.50
335_E	339_D	1.132	0.50
56_I	118_P	1.122	0.50
115_S	119_V	1.120	0.49
221_D	225_P	1.115	0.49
303_I	343_A	1.108	0.49
65_N	71_S	1.106	0.48
64_V	341_M	1.102	0.48
314_R	355_A	1.099	0.48
88_V	115_S	1.094	0.48
140_D	143_I	1.093	0.48
176_T	368_S	1.093	0.48
5_L	247_T	1.093	0.48
165_A	190_M	1.092	0.48
19_R	52_D	1.088	0.47
288_V	312_A	1.085	0.47
166_E	169_P	1.085	0.47
17_M	32_R	1.078	0.47
47_H	213_H	1.069	0.46
122_V	289_L	1.068	0.46
388_R	391_A	1.066	0.46
205_E	212_A	1.066	0.46
249_R	253_H	1.066	0.46
231_A	269_Q	1.061	0.46
68_I	95_V	1.055	0.45
168_L	190_M	1.054	0.45
108_R	152_Q	1.051	0.45
270_I	311_E	1.050	0.45
86_T	90_Y	1.046	0.45
419_R	423_D	1.046	0.45
305_S	344_Y	1.041	0.44
146_V	157_M	1.040	0.44
140_D	205_E	1.034	0.44
64_V	119_V	1.029	0.44
139_P	143_I	1.028	0.44
90_Y	341_M	1.026	0.43
119_V	268_D	1.026	0.43
320_L	344_Y	1.024	0.43
406_R	422_Q	1.022	0.43
65_N	260_E	1.020	0.43
296_I	349_H	1.018	0.43
342_A	345_R	1.017	0.43
65_N	122_V	1.013	0.43
276_R	286_F	1.011	0.42
54_M	93_D	1.008	0.42
292_L	305_S	1.006	0.42
62_T	352_D	1.001	0.42
184_S	417_S	1.001	0.42
296_I	364_D	0.996	0.42
366_A	369_E	0.996	0.42
17_M	42_I	0.994	0.41
4_Q	214_D	0.993	0.41
49_D	113_D	0.992	0.41
35_V	41_V	0.991	0.41
61_A	345_R	0.990	0.41
207_C	210_L	0.988	0.41
35_V	55_I	0.984	0.41
377_N	381_D	0.981	0.41
281_C	286_F	0.981	0.41
311_E	315_A	0.978	0.40
406_R	419_R	0.977	0.40
93_D	345_R	0.963	0.39
260_E	289_L	0.959	0.39
220_G	260_E	0.958	0.39
59_D	278_Q	0.957	0.39
122_V	260_E	0.956	0.39
48_H	53_P	0.954	0.39
90_Y	338_R	0.952	0.39
88_V	117_V	0.951	0.39
266_P	269_Q	0.945	0.38
330_G	396_T	0.940	0.38
111_N	119_V	0.939	0.38
247_T	282_D	0.938	0.38
65_N	289_L	0.935	0.38
217_I	259_V	0.933	0.38
241_D	280_V	0.930	0.37
234_D	248_R	0.929	0.37
250_A	257_A	0.929	0.37
142_L	199_L	0.927	0.37
8_A	36_A	0.927	0.37
162_G	243_L	0.917	0.37
239_E	291_P	0.916	0.37
187_S	421_D	0.913	0.36
8_A	17_M	0.912	0.36
93_D	184_S	0.908	0.36
387_E	391_A	0.906	0.36
149_Q	152_Q	0.903	0.36
41_V	251_W	0.901	0.36
17_M	36_A	0.901	0.36
137_I	193_H	0.900	0.36
240_L	277_Q	0.899	0.36
319_M	344_Y	0.898	0.36
111_N	351_G	0.897	0.36
71_S	220_G	0.891	0.35
31_V	60_F	0.889	0.35
85_H	89_H	0.887	0.35
144_D	147_E	0.887	0.35
166_E	238_A	0.883	0.35
220_G	289_L	0.883	0.35
162_G	219_L	0.875	0.34
170_L	245_E	0.873	0.34
398_P	407_F	0.872	0.34
198_P	312_A	0.870	0.34
54_M	118_P	0.870	0.34
297_A	346_I	0.870	0.34
146_V	159_L	0.870	0.34
159_L	199_L	0.867	0.34
110_A	113_D	0.862	0.33
330_G	392_F	0.858	0.33
181_R	289_L	0.856	0.33
388_R	392_F	0.853	0.33
241_D	276_R	0.849	0.33
158_T	287_Y	0.849	0.33
383_A	386_P	0.849	0.33
247_T	350_A	0.848	0.33
144_D	148_K	0.846	0.33
333_D	395_Q	0.846	0.33
37_D	283_G	0.845	0.33
409_S	425_R	0.845	0.33
19_R	22_D	0.844	0.32
172_D	282_D	0.840	0.32
62_T	314_R	0.835	0.32
294_T	364_D	0.835	0.32
65_N	220_G	0.833	0.32
267_M	270_I	0.832	0.32
13_V	29_E	0.830	0.32
64_V	254_G	0.830	0.32
71_S	260_E	0.829	0.32
272_A	275_D	0.828	0.32
161_A	217_I	0.827	0.32
240_L	273_N	0.825	0.31
175_T	368_S	0.824	0.31
122_V	287_Y	0.822	0.31
232_S	269_Q	0.819	0.31
40_A	59_D	0.815	0.31
187_S	425_R	0.814	0.31
243_L	259_V	0.811	0.31
137_I	141_L	0.807	0.30
170_L	241_D	0.801	0.30
163_V	222_G	0.800	0.30
161_A	269_Q	0.800	0.30
91_G	337_V	0.799	0.30
393_H	406_R	0.797	0.30
94_T	319_M	0.796	0.30
71_S	289_L	0.796	0.30
163_V	167_H	0.791	0.30
40_A	55_I	0.786	0.29
139_P	205_E	0.785	0.29
67_N	220_G	0.781	0.29
157_M	210_L	0.781	0.29
97_D	221_D	0.780	0.29
240_L	276_R	0.779	0.29
77_I	106_G	0.778	0.29
177_G	185_I	0.774	0.29
141_L	149_Q	0.772	0.29
68_I	134_V	0.772	0.29
5_L	254_G	0.770	0.28
140_D	194_G	0.769	0.28
97_D	225_P	0.767	0.28
71_S	122_V	0.763	0.28
66_A	84_L	0.761	0.28
158_T	289_L	0.761	0.28
175_T	369_E	0.761	0.28
142_L	145_V	0.761	0.28
67_N	178_I	0.760	0.28
380_F	389_A	0.760	0.28
122_V	220_G	0.760	0.28
227_S	351_G	0.756	0.28
200_Y	203_Y	0.747	0.27
273_N	287_Y	0.746	0.27
168_L	379_Q	0.746	0.27
159_L	164_L	0.744	0.27
309_A	367_L	0.743	0.27
86_T	334_A	0.741	0.27
158_T	231_A	0.740	0.27
146_V	161_A	0.739	0.27
157_M	215_V	0.739	0.27
236_Q	288_V	0.736	0.27
34_A	59_D	0.735	0.27
363_W	384_L	0.733	0.27
393_H	409_S	0.732	0.27
268_D	275_D	0.731	0.26
339_D	343_A	0.730	0.26
384_L	387_E	0.727	0.26
23_R	54_M	0.724	0.26
70_N	100_T	0.724	0.26
121_T	223_L	0.723	0.26
33_E	212_A	0.723	0.26
169_P	320_L	0.718	0.26
81_L	115_S	0.718	0.26
376_W	410_M	0.714	0.26
184_S	420_I	0.712	0.26
152_Q	213_H	0.711	0.25
65_N	70_N	0.709	0.25
158_T	221_D	0.709	0.25
203_Y	217_I	0.708	0.25
143_I	147_E	0.707	0.25
149_Q	177_G	0.707	0.25
311_E	314_R	0.705	0.25
172_D	234_D	0.704	0.25
37_D	58_R	0.704	0.25
330_G	379_Q	0.703	0.25
14_T	42_I	0.701	0.25
304_T	323_V	0.695	0.25
8_A	32_R	0.694	0.25
181_R	260_E	0.693	0.25
150_A	209_I	0.692	0.25
392_F	396_T	0.690	0.24
170_L	242_T	0.688	0.24
9_R	254_G	0.686	0.24
54_M	94_T	0.684	0.24
393_H	407_F	0.684	0.24
89_H	345_R	0.684	0.24
170_L	234_D	0.683	0.24
62_T	359_G	0.682	0.24
252_D	267_M	0.681	0.24
159_L	210_L	0.679	0.24
27_D	30_V	0.679	0.24
208_E	211_Q	0.677	0.24
236_Q	240_L	0.673	0.24
393_H	396_T	0.672	0.24
78_D	85_H	0.667	0.23
158_T	178_I	0.665	0.23
116_P	155_D	0.664	0.23
307_I	310_T	0.663	0.23
48_H	51_L	0.660	0.23
81_L	85_H	0.660	0.23
18_R	296_I	0.659	0.23
4_Q	8_A	0.657	0.23
95_V	117_V	0.653	0.23
109_T	113_D	0.652	0.23
101_G	185_I	0.651	0.23
163_V	205_E	0.649	0.23
127_A	314_R	0.649	0.23
78_D	110_A	0.647	0.22
109_T	334_A	0.646	0.22
305_S	406_R	0.646	0.22
56_I	390_Q	0.644	0.22
157_M	164_L	0.644	0.22
86_T	89_H	0.643	0.22
155_D	216_T	0.642	0.22
238_A	367_L	0.642	0.22
122_V	181_R	0.642	0.22
203_Y	243_L	0.641	0.22
131_V	141_L	0.640	0.22
32_R	36_A	0.639	0.22
215_V	381_D	0.638	0.22
205_E	208_E	0.638	0.22
354_A	382_L	0.636	0.22
228_V	368_S	0.635	0.22
204_D	253_H	0.634	0.22
121_T	145_V	0.634	0.22
298_P	367_L	0.633	0.22
384_L	389_A	0.629	0.22
170_L	235_A	0.629	0.22
34_A	58_R	0.628	0.22
310_T	314_R	0.627	0.22
135_T	192_E	0.624	0.21
158_T	181_R	0.623	0.21
334_A	341_M	0.622	0.21
362_D	366_A	0.622	0.21
243_L	284_A	0.618	0.21
346_I	384_L	0.617	0.21
374_F	407_F	0.615	0.21
130_R	193_H	0.612	0.21
6_Q	10_D	0.611	0.21
311_E	342_A	0.610	0.21
107_I	111_N	0.610	0.21
143_I	202_H	0.609	0.21
244_G	281_C	0.608	0.21
70_N	331_L	0.608	0.21
13_V	17_M	0.607	0.21
97_D	121_T	0.607	0.21
342_A	346_I	0.606	0.21
244_G	284_A	0.605	0.21
296_I	345_R	0.605	0.21
115_S	184_S	0.605	0.21
126_E	379_Q	0.602	0.21
4_Q	274_V	0.602	0.21
135_T	185_I	0.601	0.20
237_F	240_L	0.600	0.20
43_P	216_T	0.600	0.20
100_T	420_I	0.600	0.20
162_G	206_L	0.598	0.20
100_T	222_G	0.598	0.20
96_M	289_L	0.597	0.20
128_V	231_A	0.597	0.20
15_D	32_R	0.597	0.20
260_E	287_Y	0.597	0.20
363_W	382_L	0.596	0.20
56_I	124_I	0.595	0.20
12_T	355_A	0.594	0.20
88_V	114_N	0.594	0.20
176_T	186_L	0.593	0.20
94_T	156_Y	0.593	0.20
65_N	331_L	0.592	0.20
201_T	205_E	0.591	0.20
16_A	19_R	0.590	0.20
203_Y	250_A	0.590	0.20
72_D	333_D	0.589	0.20
232_S	276_R	0.588	0.20
181_R	287_Y	0.588	0.20
143_I	222_G	0.588	0.20
269_Q	272_A	0.587	0.20
104_L	424_A	0.587	0.20
142_L	198_P	0.586	0.20
185_I	368_S	0.586	0.20
110_A	114_N	0.585	0.20
7_H	10_D	0.585	0.20
210_L	255_V	0.583	0.20
45_N	155_D	0.583	0.20
25_G	358_P	0.582	0.20
247_T	351_G	0.582	0.20
374_F	418_M	0.582	0.20
10_D	252_D	0.580	0.20
274_V	288_V	0.579	0.20
157_M	206_L	0.579	0.20
80_E	83_K	0.578	0.20
225_P	312_A	0.578	0.20
100_T	220_G	0.578	0.20
135_T	177_G	0.576	0.19
43_P	54_M	0.575	0.19
167_H	245_E	0.575	0.19
45_N	48_H	0.574	0.19
122_V	331_L	0.570	0.19
133_D	136_D	0.570	0.19
96_M	120_G	0.570	0.19
97_D	288_V	0.569	0.19
265_V	276_R	0.568	0.19
272_A	279_E	0.568	0.19
60_F	313_A	0.568	0.19
50_A	64_V	0.567	0.19
161_A	288_V	0.567	0.19
231_A	287_Y	0.567	0.19
67_N	71_S	0.566	0.19
255_V	280_V	0.566	0.19
97_D	154_V	0.564	0.19
78_D	82_E	0.564	0.19
236_Q	322_Y	0.563	0.19
92_A	122_V	0.563	0.19
32_R	395_Q	0.563	0.19
158_T	162_G	0.562	0.19
203_Y	259_V	0.561	0.19
162_G	376_W	0.561	0.19
386_P	389_A	0.560	0.19
65_N	287_Y	0.559	0.19
64_V	90_Y	0.559	0.19
274_V	278_Q	0.559	0.19
112_I	119_V	0.558	0.19
120_G	262_P	0.557	0.19
5_L	35_V	0.557	0.19
222_G	284_A	0.557	0.19
162_G	222_G	0.557	0.19
58_R	62_T	0.554	0.19
267_M	315_A	0.554	0.19
178_I	220_G	0.554	0.19
309_A	319_M	0.554	0.19
70_N	104_L	0.554	0.19
177_G	187_S	0.552	0.19
3_T	6_Q	0.552	0.19
15_D	335_E	0.552	0.19
101_G	126_E	0.552	0.19
100_T	187_S	0.552	0.19
56_I	112_I	0.552	0.19
405_A	409_S	0.552	0.19
126_E	177_G	0.551	0.18
421_D	425_R	0.551	0.18
198_P	288_V	0.550	0.18
298_P	329_L	0.550	0.18
100_T	181_R	0.549	0.18
140_D	206_L	0.547	0.18
367_L	383_A	0.546	0.18
91_G	409_S	0.546	0.18
148_K	152_Q	0.546	0.18
86_T	341_M	0.545	0.18
19_R	23_R	0.545	0.18
66_A	92_A	0.545	0.18
162_G	273_N	0.545	0.18
97_D	320_L	0.545	0.18
97_D	349_H	0.544	0.18
159_L	190_M	0.544	0.18
35_V	259_V	0.542	0.18
154_V	228_V	0.542	0.18
315_A	378_R	0.542	0.18
394_D	397_L	0.541	0.18
143_I	258_M	0.540	0.18
243_L	291_P	0.540	0.18
49_D	213_H	0.540	0.18
234_D	241_D	0.540	0.18
234_D	245_E	0.540	0.18
247_T	277_Q	0.539	0.18
312_A	375_D	0.538	0.18
210_L	215_V	0.537	0.18
46_H	214_D	0.537	0.18
390_Q	394_D	0.535	0.18
231_A	266_P	0.535	0.18
67_N	122_V	0.535	0.18
373_N	422_Q	0.535	0.18
194_G	345_R	0.535	0.18
359_G	369_E	0.535	0.18
8_A	11_G	0.534	0.18
27_D	33_E	0.532	0.18
227_S	379_Q	0.532	0.18
267_M	356_G	0.532	0.18
105_D	109_T	0.532	0.18
58_R	278_Q	0.531	0.18
97_D	309_A	0.531	0.18
81_L	114_N	0.531	0.18
22_D	61_A	0.531	0.18
120_G	289_L	0.531	0.18
139_P	195_E	0.530	0.18
241_D	278_Q	0.529	0.18
138_T	141_L	0.528	0.18
76_D	409_S	0.527	0.18
135_T	188_Q	0.527	0.18
126_E	145_V	0.527	0.18
259_V	396_T	0.527	0.18
128_V	259_V	0.526	0.18
94_T	155_D	0.524	0.17
66_A	90_Y	0.524	0.17
145_V	339_D	0.524	0.17
163_V	223_L	0.523	0.17
335_E	387_E	0.522	0.17
177_G	372_Y	0.520	0.17
189_W	193_H	0.519	0.17
342_A	388_R	0.519	0.17
363_W	368_S	0.518	0.17
85_H	217_I	0.517	0.17
247_T	257_A	0.517	0.17
345_R	386_P	0.516	0.17
204_D	217_I	0.514	0.17
122_V	158_T	0.513	0.17
65_N	181_R	0.512	0.17
164_L	235_A	0.512	0.17
198_P	375_D	0.512	0.17
297_A	304_T	0.512	0.17
156_Y	278_Q	0.511	0.17
213_H	353_V	0.510	0.17
54_M	117_V	0.510	0.17
107_I	177_G	0.510	0.17
206_L	217_I	0.509	0.17
5_L	9_R	0.507	0.17
41_V	319_M	0.506	0.17
33_E	252_D	0.506	0.17
6_Q	253_H	0.505	0.17
181_R	231_A	0.505	0.17
12_T	49_D	0.505	0.17
67_N	260_E	0.505	0.17
240_L	323_V	0.504	0.17
61_A	310_T	0.504	0.17
64_V	173_D	0.504	0.17
140_D	151_K	0.503	0.17
186_L	206_L	0.503	0.17
313_A	393_H	0.503	0.17
381_D	390_Q	0.502	0.17
58_R	355_A	0.501	0.17
143_I	198_P	0.501	0.17
243_L	356_G	0.501	0.17
161_A	203_Y	0.501	0.17
228_V	384_L	0.500	0.17
211_Q	217_I	0.500	0.17

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3epoA	2	0.8193	100	0.025	Contact Map
4s28A	2	0.9139	100	0.035	Contact Map
1w8sA	4	0.4832	93.1	0.975	Contact Map
4djdD	1	0.5084	92.2	0.976	Contact Map
2dqwA	2	0.4643	91.1	0.977	Contact Map
3f4wA	2	0.4265	90.1	0.977	Contact Map
1aj0A	1	0.5063	88.8	0.978	Contact Map
4cq8A	1	0.5231	87.8	0.978	Contact Map
2h9aB	1	0.4958	86.3	0.979	Contact Map
2y5sA	2	0.4937	85.6	0.979	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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