Q9HRF7 - HALSA - GREMLIN Contacts

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Q9HRF7 - DNA damage-inducible protein

UniProt:	Q9HRF7	Sequences: MQTFFSGASRAPVSMVPNPFSWLLRAVGVAIARLGLISESRARRTAELAWPRILTGIGRMSKSAADVAMVGAALGSAAITGVGYAGPFWGAAFSIGGGLAAGTIALVSQRFSADEIADAGQALRSSAALTVAATLPIAVLFYSHPAALIGLLTDRQAEIAFGADYLRVVAFGVPFAGLNLIGSRALIGADDAYTAMVLRGGGALANIGLNGVFIFGLGWGVVGAGLGTVLSNVVVTTAFVVGLSRGRLPAVGAFPMTVSVRGAYWVRDDCWDIVTIGLPVVGRNSVWTLARFPLLAFMSLFGQPVAAAYIIVRRVFGIMNTPGWGFGLAASSLVGQELGQGRESTAAAYGREITLYSVVMYVMFAGVVCAFAGQIVGVFVDSASDPSVPIAVTMVYVAAAAVIPQGIGATVAGALDATGDTRWPFYSRAVGMLGALPLVYLGATTPLGLYGIYLSLFSETCVPAVVNYLRFRSGKWKAISREYRPDAAD	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	489 (425)
Sequences:	17650 (13244)
Seq/√Len:	642.4

ECOLI - YEEO DINF MDTK
BACSU - YISQ YPNP YOEA NORM
HALSA - Q9HRF7 Q9HMS7 Q9HRF2 Q9HN79

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
115_E	118_D	4.644	1.00
175_F	233_V	3.946	1.00
164_D	222_V	3.442	1.00
83_G	310_I	3.134	1.00
376_V	391_A	3.109	1.00
371_F	374_Q	3.097	1.00
146_A	163_A	3.070	1.00
108_S	335_G	3.031	1.00
271_W	275_T	2.845	1.00
146_A	150_G	2.821	1.00
342_R	345_T	2.796	1.00
191_D	194_T	2.770	1.00
144_H	147_A	2.757	1.00
103_T	126_S	2.581	1.00
205_A	234_V	2.565	1.00
168_V	222_V	2.553	1.00
267_R	271_W	2.481	1.00
163_A	167_R	2.406	1.00
69_M	214_I	2.394	1.00
77_A	157_A	2.357	1.00
69_M	211_G	2.319	1.00
420_D	470_R	2.316	1.00
155_R	303_Q	2.302	1.00
212_V	217_L	2.296	1.00
110_R	118_D	2.246	1.00
202_G	235_V	2.243	1.00
161_F	164_D	2.207	1.00
81_G	161_F	2.185	1.00
43_R	47_E	2.179	1.00
178_L	236_T	2.099	1.00
393_T	450_Y	2.084	1.00
351_R	355_L	2.080	1.00
330_A	353_I	2.073	1.00
198_L	238_A	2.066	1.00
168_V	225_G	1.978	1.00
121_Q	266_V	1.977	1.00
160_A	164_D	1.971	1.00
308_A	390_I	1.970	1.00
172_G	229_V	1.953	1.00
66_D	228_T	1.952	1.00
386_P	389_P	1.951	1.00
222_V	226_L	1.951	1.00
372_A	396_Y	1.924	1.00
448_G	451_G	1.913	1.00
373_G	392_V	1.903	1.00
70_V	224_A	1.889	1.00
130_T	181_I	1.884	1.00
304_P	386_P	1.882	1.00
219_W	226_L	1.877	1.00
75_G	78_A	1.871	1.00
214_I	224_A	1.868	1.00
53_I	325_G	1.864	1.00
69_M	210_N	1.834	1.00
212_V	216_G	1.829	1.00
110_R	115_E	1.804	1.00
150_G	159_I	1.772	1.00
50_W	54_L	1.765	1.00
337_E	345_T	1.759	1.00
193_Y	197_V	1.748	1.00
110_R	113_A	1.740	1.00
145_P	163_A	1.730	1.00
168_V	226_L	1.708	1.00
237_T	241_V	1.702	1.00
338_L	418_T	1.700	1.00
171_F	174_P	1.679	1.00
404_P	461_C	1.676	1.00
333_L	349_Y	1.672	1.00
350_G	411_V	1.668	1.00
372_A	392_V	1.666	1.00
198_L	239_F	1.663	1.00
147_A	150_G	1.659	1.00
369_C	396_Y	1.650	1.00
266_V	269_D	1.636	1.00
204_L	208_G	1.628	1.00
49_A	329_A	1.614	1.00
175_F	236_T	1.612	1.00
348_A	351_R	1.608	1.00
357_S	406_G	1.599	1.00
106_L	122_A	1.561	1.00
211_G	215_F	1.555	1.00
159_I	163_A	1.540	1.00
209_L	227_G	1.539	1.00
65_A	207_I	1.529	1.00
365_A	369_C	1.527	1.00
156_Q	160_A	1.521	1.00
157_A	303_Q	1.520	1.00
157_A	160_A	1.518	1.00
338_L	346_A	1.513	1.00
347_A	351_R	1.508	1.00
141_F	170_A	1.507	1.00
373_G	377_G	1.504	1.00
383_A	389_P	1.500	1.00
210_N	224_A	1.487	1.00
348_A	352_E	1.486	1.00
145_P	167_R	1.483	1.00
205_A	209_L	1.482	1.00
420_D	423_W	1.476	1.00
168_V	229_V	1.473	1.00
42_A	352_E	1.473	1.00
377_G	388_V	1.472	1.00
337_E	342_R	1.462	1.00
344_S	348_A	1.454	1.00
182_G	239_F	1.453	1.00
465_V	469_L	1.450	1.00
149_I	159_I	1.443	1.00
150_G	156_Q	1.440	1.00
85_A	166_L	1.439	1.00
138_A	174_P	1.439	1.00
350_G	414_A	1.438	1.00
374_Q	377_G	1.437	1.00
76_S	382_S	1.430	1.00
70_V	82_V	1.426	1.00
146_A	160_A	1.426	1.00
208_G	211_G	1.410	1.00
241_V	245_R	1.401	1.00
110_R	122_A	1.394	1.00
41_R	333_L	1.384	1.00
447_L	451_G	1.384	1.00
389_P	393_T	1.376	1.00
213_F	219_W	1.373	1.00
116_I	120_G	1.372	1.00
397_V	454_L	1.359	1.00
197_V	201_G	1.359	1.00
54_L	196_M	1.358	1.00
39_E	43_R	1.354	1.00
222_V	225_G	1.348	1.00
66_D	206_N	1.344	1.00
208_G	212_V	1.342	1.00
392_V	396_Y	1.340	1.00
118_D	121_Q	1.338	1.00
374_Q	378_V	1.335	1.00
117_A	121_Q	1.331	1.00
355_L	359_V	1.326	1.00
80_T	307_A	1.315	1.00
213_F	217_L	1.314	1.00
147_A	151_L	1.310	1.00
382_S	386_P	1.307	1.00
369_C	399_A	1.304	1.00
111_F	336_Q	1.303	1.00
423_W	470_R	1.299	1.00
198_L	242_G	1.298	1.00
109_Q	113_A	1.292	1.00
111_F	119_A	1.291	1.00
74_L	78_A	1.282	1.00
209_L	230_L	1.272	1.00
78_A	161_F	1.269	1.00
58_G	200_G	1.266	1.00
357_S	410_T	1.261	1.00
366_G	370_A	1.253	1.00
469_L	472_R	1.252	1.00
109_Q	335_G	1.246	1.00
315_V	375_I	1.244	1.00
118_D	269_D	1.242	1.00
146_A	159_I	1.239	1.00
343_E	347_A	1.236	1.00
67_V	314_R	1.231	1.00
376_V	388_V	1.226	1.00
383_A	386_P	1.221	1.00
422_R	426_Y	1.221	1.00
112_S	339_G	1.219	1.00
451_G	455_S	1.216	1.00
109_Q	419_G	1.207	1.00
42_A	356_Y	1.200	1.00
468_Y	472_R	1.193	1.00
210_N	227_G	1.190	1.00
268_D	271_W	1.186	1.00
201_G	238_A	1.179	1.00
76_S	304_P	1.176	1.00
278_L	282_G	1.173	1.00
77_A	303_Q	1.169	1.00
81_G	158_E	1.159	1.00
211_G	216_G	1.151	1.00
149_I	162_G	1.149	1.00
206_N	228_T	1.147	1.00
72_A	215_F	1.142	1.00
213_F	230_L	1.133	1.00
125_S	265_W	1.133	1.00
125_S	270_C	1.129	1.00
138_A	142_Y	1.129	1.00
82_V	221_V	1.126	1.00
123_L	185_A	1.124	1.00
67_V	79_I	1.124	1.00
390_I	393_T	1.122	1.00
107_V	188_G	1.122	1.00
447_L	454_L	1.120	1.00
72_A	381_D	1.120	1.00
211_G	214_I	1.118	1.00
142_Y	167_R	1.111	1.00
334_V	346_A	1.106	1.00
45_T	353_I	1.102	1.00
77_A	161_F	1.099	1.00
304_P	390_I	1.099	1.00
129_L	270_C	1.097	1.00
327_G	413_G	1.095	1.00
430_V	434_G	1.094	1.00
213_F	216_G	1.084	1.00
426_Y	430_V	1.081	1.00
388_V	391_A	1.077	1.00
427_S	467_N	1.073	1.00
259_S	262_G	1.068	1.00
408_G	460_T	1.067	1.00
194_T	242_G	1.061	1.00
216_G	219_W	1.060	1.00
350_G	471_F	1.058	1.00
130_T	177_G	1.058	1.00
359_V	363_M	1.058	1.00
40_S	43_R	1.055	1.00
305_V	449_L	1.055	1.00
112_S	340_Q	1.054	1.00
265_W	270_C	1.052	1.00
191_D	195_A	1.051	1.00
380_V	383_A	1.048	1.00
312_V	394_M	1.048	1.00
205_A	231_S	1.045	1.00
167_R	171_F	1.041	1.00
131_V	178_L	1.041	1.00
411_V	471_F	1.036	1.00
415_L	470_R	1.027	1.00
386_P	390_I	1.025	1.00
352_E	356_Y	1.018	1.00
66_D	210_N	1.016	1.00
120_G	262_G	1.007	1.00
272_D	275_T	0.995	1.00
46_A	50_W	0.994	1.00
380_V	387_S	0.994	1.00
296_A	300_L	0.990	1.00
434_G	437_P	0.984	1.00
226_L	229_V	0.980	1.00
63_S	86_G	0.978	1.00
143_S	147_A	0.977	1.00
126_S	273_I	0.977	1.00
111_F	189_A	0.975	1.00
190_D	336_Q	0.973	1.00
121_Q	269_D	0.969	1.00
337_E	349_Y	0.969	1.00
200_G	204_L	0.966	1.00
111_F	116_I	0.965	1.00
122_A	269_D	0.963	1.00
182_G	236_T	0.963	1.00
397_V	450_Y	0.960	1.00
389_P	392_V	0.956	1.00
138_A	171_F	0.955	1.00
325_G	329_A	0.948	1.00
373_G	389_P	0.948	1.00
315_V	368_V	0.943	1.00
435_A	462_V	0.938	1.00
44_R	47_E	0.932	1.00
145_P	166_L	0.932	1.00
394_M	449_L	0.931	1.00
109_Q	338_L	0.929	1.00
84_Y	154_D	0.928	1.00
376_V	392_V	0.925	1.00
363_M	367_V	0.918	1.00
96_G	177_G	0.917	1.00
362_V	366_G	0.917	1.00
404_P	464_A	0.914	1.00
143_S	167_R	0.913	1.00
52_R	328_L	0.911	1.00
128_A	265_W	0.910	1.00
210_N	228_T	0.909	1.00
459_E	463_P	0.903	1.00
68_A	71_G	0.903	1.00
308_A	387_S	0.902	1.00
164_D	167_R	0.900	1.00
229_V	233_V	0.899	1.00
233_V	237_T	0.899	1.00
354_T	407_I	0.896	1.00
309_Y	453_Y	0.896	1.00
132_A	136_P	0.893	1.00
238_A	241_V	0.887	1.00
369_C	373_G	0.884	1.00
346_A	350_G	0.883	1.00
438_L	458_S	0.881	1.00
255_P	259_S	0.879	1.00
69_M	215_F	0.877	1.00
65_A	206_N	0.877	1.00
311_I	379_F	0.877	1.00
161_F	221_V	0.873	1.00
334_V	417_A	0.872	1.00
89_W	169_V	0.872	1.00
156_Q	159_I	0.871	1.00
124_R	263_A	0.868	1.00
65_A	203_A	0.865	1.00
171_F	229_V	0.859	1.00
286_V	429_A	0.853	1.00
191_D	242_G	0.853	1.00
450_Y	454_L	0.851	1.00
186_L	243_L	0.848	1.00
363_M	366_G	0.847	1.00
346_A	418_T	0.845	1.00
179_N	235_V	0.845	1.00
245_R	248_L	0.845	1.00
370_A	374_Q	0.844	1.00
48_L	192_A	0.843	1.00
209_L	213_F	0.843	1.00
206_N	210_N	0.841	1.00
282_G	425_F	0.839	1.00
388_V	392_V	0.838	1.00
103_T	107_V	0.838	1.00
196_M	200_G	0.837	1.00
308_A	391_A	0.836	1.00
182_G	243_L	0.833	1.00
305_V	390_I	0.832	1.00
455_S	459_E	0.831	1.00
191_D	246_G	0.830	1.00
334_V	414_A	0.829	1.00
201_G	205_A	0.828	1.00
136_P	140_L	0.827	1.00
142_Y	146_A	0.827	1.00
298_M	449_L	0.825	1.00
298_M	452_I	0.825	1.00
323_G	361_Y	0.820	1.00
348_A	355_L	0.818	1.00
197_V	200_G	0.817	1.00
345_T	348_A	0.817	1.00
58_G	203_A	0.815	1.00
80_T	158_E	0.815	1.00
314_R	379_F	0.813	1.00
299_S	306_A	0.812	1.00
140_L	144_H	0.810	1.00
344_S	351_R	0.809	1.00
109_Q	272_D	0.809	1.00
139_V	143_S	0.806	1.00
234_V	238_A	0.806	1.00
337_E	340_Q	0.806	1.00
226_L	230_L	0.806	1.00
70_V	214_I	0.806	1.00
145_P	170_A	0.800	1.00
44_R	333_L	0.798	1.00
297_F	300_L	0.795	1.00
275_T	422_R	0.792	1.00
76_S	387_S	0.788	1.00
431_G	463_P	0.788	1.00
107_V	185_A	0.788	1.00
128_A	263_A	0.786	1.00
407_I	464_A	0.786	1.00
186_L	194_T	0.786	1.00
186_L	239_F	0.783	1.00
77_A	158_E	0.782	1.00
106_L	276_I	0.782	1.00
326_F	353_I	0.782	1.00
206_N	231_S	0.781	1.00
353_I	410_T	0.781	1.00
44_R	336_Q	0.780	1.00
160_A	163_A	0.780	1.00
108_S	188_G	0.776	1.00
45_T	352_E	0.775	1.00
255_P	258_V	0.774	1.00
126_S	181_I	0.773	1.00
168_V	171_F	0.772	1.00
311_I	391_A	0.768	1.00
269_D	272_D	0.767	1.00
440_Y	443_A	0.765	1.00
113_A	339_G	0.763	1.00
461_C	465_V	0.763	1.00
42_A	46_A	0.763	1.00
187_I	195_A	0.762	1.00
58_G	61_S	0.762	1.00
128_A	132_A	0.760	1.00
62_K	228_T	0.760	1.00
352_E	355_L	0.759	1.00
95_I	281_V	0.756	1.00
358_V	362_V	0.752	1.00
210_N	214_I	0.749	1.00
272_D	419_G	0.749	1.00
337_E	346_A	0.748	1.00
68_A	378_V	0.748	1.00
164_D	221_V	0.746	1.00
400_A	403_I	0.744	1.00
359_V	362_V	0.741	1.00
355_L	358_V	0.739	1.00
49_A	325_G	0.739	1.00
442_G	446_P	0.739	1.00
149_I	166_L	0.736	1.00
362_V	403_I	0.735	1.00
241_V	244_S	0.734	1.00
81_G	221_V	0.734	1.00
117_A	262_G	0.731	1.00
240_V	244_S	0.730	1.00
411_V	467_N	0.729	1.00
42_A	355_L	0.727	1.00
120_G	259_S	0.726	1.00
158_E	306_A	0.724	1.00
106_L	110_R	0.724	1.00
55_T	199_R	0.723	1.00
308_A	394_M	0.719	1.00
274_V	278_L	0.717	1.00
225_G	229_V	0.716	1.00
201_G	234_V	0.716	1.00
397_V	457_F	0.714	1.00
64_A	318_I	0.714	1.00
297_F	439_V	0.713	1.00
61_S	65_A	0.712	1.00
71_G	79_I	0.711	1.00
157_A	161_F	0.711	1.00
454_L	457_F	0.710	1.00
68_A	72_A	0.705	1.00
423_W	427_S	0.703	1.00
134_T	174_P	0.701	1.00
326_F	360_M	0.700	1.00
170_A	173_V	0.700	1.00
371_F	375_I	0.700	1.00
45_T	329_A	0.699	1.00
285_S	289_L	0.698	1.00
194_T	238_A	0.698	1.00
105_A	109_Q	0.696	1.00
334_V	350_G	0.696	1.00
373_G	388_V	0.695	1.00
326_F	357_S	0.693	1.00
358_V	406_G	0.691	1.00
136_P	139_V	0.688	1.00
144_H	148_L	0.687	1.00
451_G	454_L	0.687	1.00
166_L	170_A	0.686	1.00
372_A	376_V	0.684	1.00
107_V	119_A	0.683	1.00
171_F	175_F	0.682	1.00
301_F	305_V	0.682	1.00
81_G	162_G	0.681	1.00
77_A	80_T	0.681	1.00
57_I	61_S	0.680	1.00
344_S	347_A	0.680	1.00
297_F	440_Y	0.678	1.00
70_V	221_V	0.678	1.00
372_A	395_V	0.677	1.00
441_L	444_T	0.677	1.00
449_L	453_Y	0.676	1.00
139_V	142_Y	0.675	1.00
276_I	421_T	0.673	1.00
205_A	230_L	0.671	1.00
298_M	309_Y	0.670	1.00
219_W	222_V	0.670	1.00
369_C	372_A	0.670	1.00
277_G	281_V	0.670	1.00
65_A	69_M	0.667	1.00
304_P	307_A	0.665	1.00
124_R	262_G	0.665	1.00
294_L	452_I	0.661	1.00
167_R	222_V	0.660	1.00
299_S	302_G	0.660	1.00
62_K	202_G	0.659	1.00
118_D	122_A	0.659	1.00
213_F	224_A	0.657	1.00
330_A	334_V	0.657	1.00
200_G	203_A	0.653	1.00
230_L	233_V	0.652	1.00
172_G	232_N	0.652	1.00
78_A	220_G	0.652	1.00
396_Y	400_A	0.650	1.00
165_Y	210_N	0.648	1.00
172_G	175_F	0.648	1.00
360_M	364_F	0.647	1.00
302_G	305_V	0.647	1.00
231_S	234_V	0.645	1.00
158_E	161_F	0.645	1.00
413_G	417_A	0.642	1.00
279_P	425_F	0.642	1.00
343_E	346_A	0.639	1.00
159_I	162_G	0.639	1.00
361_Y	406_G	0.638	1.00
117_A	120_G	0.636	1.00
370_A	373_G	0.635	1.00
121_Q	124_R	0.632	1.00
98_G	281_V	0.632	1.00
358_V	407_I	0.632	1.00
121_Q	125_S	0.630	1.00
70_V	78_A	0.627	1.00
115_E	121_Q	0.627	1.00
383_A	388_V	0.623	1.00
387_S	391_A	0.621	1.00
466_V	469_L	0.620	1.00
170_A	174_P	0.617	1.00
411_V	468_Y	0.617	1.00
142_Y	171_F	0.616	1.00
320_N	405_Q	0.615	1.00
338_L	343_E	0.615	1.00
294_L	439_V	0.614	1.00
336_Q	340_Q	0.612	1.00
278_L	281_V	0.612	1.00
322_P	360_M	0.612	1.00
79_I	311_I	0.612	1.00
154_D	299_S	0.611	1.00
105_A	276_I	0.609	1.00
319_M	364_F	0.609	1.00
399_A	403_I	0.608	1.00
367_V	371_F	0.608	1.00
238_A	242_G	0.607	1.00
305_V	308_A	0.606	1.00
380_V	388_V	0.606	1.00
331_S	416_D	0.605	1.00
134_T	138_A	0.605	1.00
183_S	187_I	0.604	1.00
268_D	272_D	0.604	1.00
74_L	221_V	0.604	1.00
213_F	226_L	0.603	1.00
441_L	445_T	0.602	1.00
308_A	453_Y	0.601	1.00
70_V	74_L	0.601	1.00
356_Y	359_V	0.600	1.00
436_L	440_Y	0.600	1.00
135_L	139_V	0.599	1.00
215_F	219_W	0.599	1.00
146_A	167_R	0.598	1.00
182_G	240_V	0.596	1.00
104_I	184_R	0.595	1.00
295_L	299_S	0.594	1.00
113_A	341_G	0.594	1.00
61_S	203_A	0.593	1.00
62_K	232_N	0.593	1.00
316_F	402_V	0.590	1.00
354_T	358_V	0.588	1.00
354_T	411_V	0.588	1.00
179_N	236_T	0.587	1.00
86_G	90_G	0.586	1.00
206_N	227_G	0.585	1.00
164_D	168_V	0.585	1.00
134_T	170_A	0.584	1.00
427_S	466_V	0.584	1.00
105_A	335_G	0.584	1.00
79_I	380_V	0.581	1.00
213_F	218_G	0.581	1.00
407_I	468_Y	0.580	1.00
201_G	204_L	0.578	1.00
442_G	445_T	0.577	1.00
414_A	418_T	0.577	1.00
131_V	135_L	0.576	1.00
435_A	459_E	0.572	1.00
149_I	163_A	0.571	1.00
290_A	432_M	0.571	1.00
431_G	466_V	0.571	1.00
41_R	352_E	0.570	1.00
242_G	246_G	0.570	1.00
323_G	406_G	0.569	1.00
441_L	446_P	0.569	1.00
165_Y	224_A	0.568	1.00
92_A	173_V	0.567	1.00
454_L	458_S	0.566	1.00
430_V	466_V	0.566	1.00
40_S	44_R	0.565	1.00
80_T	83_G	0.565	1.00
401_A	457_F	0.564	1.00
135_L	138_A	0.563	1.00
69_M	227_G	0.562	1.00
436_L	439_V	0.561	1.00
149_I	154_D	0.559	1.00
78_A	81_G	0.559	1.00
207_I	211_G	0.559	1.00
142_Y	145_P	0.559	1.00
94_S	97_G	0.558	1.00
187_I	192_A	0.558	1.00
41_R	348_A	0.557	1.00
44_R	345_T	0.557	1.00
125_S	269_D	0.555	1.00
317_G	320_N	0.555	1.00
316_F	398_A	0.555	1.00
223_G	227_G	0.554	1.00
297_F	301_F	0.553	1.00
198_L	235_V	0.553	1.00
350_G	354_T	0.552	1.00
76_S	307_A	0.551	1.00
205_A	208_G	0.550	1.00
365_A	403_I	0.550	1.00
99_L	133_A	0.550	1.00
421_T	425_F	0.550	1.00
154_D	159_I	0.550	1.00
244_S	248_L	0.550	1.00
415_L	420_D	0.548	1.00
114_D	340_Q	0.546	1.00
52_R	325_G	0.546	1.00
175_F	229_V	0.546	1.00
227_G	231_S	0.545	1.00
101_A	328_L	0.544	1.00
158_E	162_G	0.544	1.00
46_A	356_Y	0.543	1.00
297_F	452_I	0.542	1.00
163_A	166_L	0.542	1.00
411_V	464_A	0.541	1.00
312_V	395_V	0.540	1.00
428_R	431_G	0.540	1.00
174_P	233_V	0.540	1.00
155_R	159_I	0.540	1.00
270_C	274_V	0.539	1.00
65_A	68_A	0.539	1.00
408_G	463_P	0.539	1.00
39_E	47_E	0.539	1.00
141_F	145_P	0.538	1.00
301_F	448_G	0.538	1.00
39_E	42_A	0.536	0.99
358_V	403_I	0.536	0.99
107_V	122_A	0.536	0.99
457_F	461_C	0.536	0.99
45_T	356_Y	0.535	0.99
99_L	281_V	0.533	0.99
194_T	246_G	0.531	0.99
138_A	170_A	0.531	0.99
148_L	151_L	0.530	0.99
220_G	223_G	0.530	0.99
52_R	192_A	0.530	0.99
399_A	402_V	0.529	0.99
142_Y	170_A	0.529	0.99
236_T	240_V	0.529	0.99
102_G	277_G	0.529	0.99
84_Y	306_A	0.529	0.99
135_L	174_P	0.528	0.99
41_R	349_Y	0.527	0.99
179_N	183_S	0.527	0.99
308_A	312_V	0.526	0.99
286_V	425_F	0.525	0.99
152_L	292_F	0.524	0.99
230_L	234_V	0.524	0.99
124_R	128_A	0.524	0.99
45_T	49_A	0.524	0.99
443_A	446_P	0.524	0.99
331_S	413_G	0.524	0.99
219_W	223_G	0.523	0.99
158_E	303_Q	0.522	0.99
351_R	471_F	0.521	0.99
377_G	381_D	0.520	0.99
258_V	262_G	0.519	0.99
119_A	123_L	0.519	0.99
140_L	143_S	0.518	0.99
244_S	247_R	0.517	0.99
138_A	143_S	0.517	0.99
63_S	169_V	0.517	0.99
465_V	468_Y	0.516	0.99
84_Y	162_G	0.512	0.99
368_V	375_I	0.512	0.99
42_A	348_A	0.511	0.99
284_N	324_W	0.509	0.99
462_V	466_V	0.507	0.99
75_G	161_F	0.507	0.99
215_F	218_G	0.504	0.99
369_C	400_A	0.504	0.99
293_P	436_L	0.503	0.99
320_N	409_A	0.503	0.99
153_T	156_Q	0.501	0.99
393_T	396_Y	0.500	0.99
186_L	242_G	0.500	0.99

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3mktA	1	0.9182	100	0.377	Contact Map
4lz6A	1	0.908	100	0.388	Contact Map
4humA	1	0.9223	100	0.389	Contact Map
3w4tA	1	0.8998	100	0.437	Contact Map
4ikvA	1	0.8466	64.9	0.954	Contact Map
4j05A	3	0.7832	60.5	0.955	Contact Map
4xnjA	1	0.4601	57.3	0.956	Contact Map
1pw4A	1	0.4479	51.9	0.957	Contact Map
3wdoA	1	0.8037	44.2	0.959	Contact Map
4zw9A	1	0.863	38.4	0.961	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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