Q9HRF3 - HALSA - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

Q9HRF3 - Uncharacterized protein

UniProt:	Q9HRF3	Sequences: MAAPSNREFSEAEAELMQATYSALREHGYVDLTIKRIADEYGKSTAAVHYYYDTKEELLAAFLDYLLEEFVASIRAVETTAPETRLSLLLDELLVDPQPNQALSVALLEMRAQAPYNEPFRERFQQNDEYTRFMLKSVISHGIDEGAFEAVDADHVARSLMTIVDGARTRSVVHGDPSALAAGRRTASEYVDATLL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	196 (179)
Sequences:	46342 (36864)
Seq/√Len:	2755.4

ECOLI - ACRR ENVR UIDR SLMA RUTR COMR NEMR BETI FABR BDCR YJDC RCDA YBIH
BACSU - YHGD YFIR FADR YEZE PKSA BSCR YTTP LMRA YVKB YVDT YXAF YDGC YVAF YDES YCNC YUXN YOBS YERO
HALSA - Q9HRF3 Q9HM72
SULSO - Q97VV1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
35_K	45_T	3.966	1.00
27_H	36_R	3.964	1.00
22_S	40_E	3.550	1.00
53_D	57_E	2.743	1.00
24_L	32_L	2.391	1.00
136_K	154_D	2.164	1.00
54_T	57_E	2.133	1.00
38_A	48_V	2.087	1.00
26_E	40_E	2.008	1.00
23_A	40_E	2.005	1.00
14_A	65_Y	1.977	1.00
19_A	40_E	1.936	1.00
23_A	32_L	1.926	1.00
23_A	36_R	1.897	1.00
136_K	140_S	1.884	1.00
12_A	15_E	1.874	1.00
87_S	188_S	1.863	1.00
81_A	84_T	1.858	1.00
15_E	19_A	1.850	1.00
13_E	61_A	1.845	1.00
85_R	141_H	1.800	1.00
35_K	39_D	1.795	1.00
23_A	27_H	1.794	1.00
140_S	153_A	1.764	1.00
91_D	184_R	1.761	1.00
140_S	144_D	1.681	1.00
21_Y	65_Y	1.663	1.00
14_A	18_Q	1.652	1.00
44_S	47_A	1.649	1.00
19_A	22_S	1.644	1.00
20_T	24_L	1.583	1.00
34_I	49_H	1.565	1.00
17_M	61_A	1.535	1.00
36_R	39_D	1.532	1.00
34_I	45_T	1.509	1.00
140_S	143_I	1.504	1.00
22_S	26_E	1.478	1.00
28_G	32_L	1.441	1.00
61_A	64_D	1.433	1.00
36_R	40_E	1.421	1.00
60_A	64_D	1.419	1.00
65_Y	69_E	1.413	1.00
21_Y	66_L	1.409	1.00
159_S	163_I	1.397	1.00
33_T	36_R	1.396	1.00
143_I	150_A	1.389	1.00
60_A	123_R	1.379	1.00
28_G	31_D	1.375	1.00
52_Y	61_A	1.359	1.00
21_Y	62_F	1.334	1.00
64_D	123_R	1.332	1.00
75_R	134_M	1.318	1.00
20_T	58_L	1.306	1.00
141_H	145_E	1.298	1.00
11_E	15_E	1.290	1.00
32_L	37_I	1.276	1.00
18_Q	65_Y	1.267	1.00
132_R	158_R	1.265	1.00
47_A	50_Y	1.265	1.00
13_E	51_Y	1.242	1.00
34_I	48_V	1.229	1.00
73_S	92_E	1.205	1.00
11_E	14_A	1.201	1.00
24_L	29_Y	1.190	1.00
142_G	147_A	1.185	1.00
45_T	49_H	1.177	1.00
27_H	31_D	1.176	1.00
84_T	88_L	1.176	1.00
19_A	23_A	1.173	1.00
105_V	109_E	1.161	1.00
57_E	61_A	1.149	1.00
132_R	136_K	1.124	1.00
91_D	188_S	1.119	1.00
48_V	58_L	1.114	1.00
87_S	91_D	1.114	1.00
142_G	148_F	1.112	1.00
43_K	47_A	1.108	1.00
17_M	52_Y	1.086	1.00
152_D	155_H	1.076	1.00
179_A	182_A	1.074	1.00
19_A	41_Y	1.072	1.00
143_I	151_V	1.071	1.00
12_A	51_Y	1.070	1.00
138_V	142_G	1.066	1.00
56_E	117_N	1.065	1.00
85_R	138_V	1.063	1.00
47_A	51_Y	1.054	1.00
83_E	87_S	1.050	1.00
134_M	137_S	1.048	1.00
88_L	91_D	1.048	1.00
44_S	50_Y	1.046	1.00
184_R	188_S	1.041	1.00
185_R	188_S	1.037	1.00
56_E	60_A	1.037	1.00
105_V	108_L	1.025	1.00
123_R	126_Q	1.025	1.00
46_A	50_Y	1.022	1.00
18_Q	22_S	1.016	1.00
29_Y	59_L	1.015	1.00
17_M	62_F	1.005	1.00
27_H	40_E	1.004	1.00
37_I	58_L	1.004	1.00
49_H	54_T	1.001	1.00
21_Y	25_R	0.989	1.00
20_T	62_F	0.985	1.00
22_S	102_A	0.980	1.00
9_F	50_Y	0.974	1.00
56_E	119_P	0.968	1.00
64_D	68_E	0.961	1.00
136_K	153_A	0.954	1.00
57_E	60_A	0.952	1.00
71_V	130_Y	0.951	1.00
96_D	100_N	0.941	1.00
143_I	153_A	0.940	1.00
80_T	88_L	0.939	1.00
129_E	133_F	0.936	1.00
38_A	45_T	0.931	1.00
137_S	141_H	0.920	1.00
79_T	85_R	0.916	1.00
71_V	75_R	0.915	1.00
65_Y	68_E	0.915	1.00
126_Q	130_Y	0.915	1.00
84_T	87_S	0.905	1.00
81_A	147_A	0.903	1.00
61_A	65_Y	0.897	1.00
104_S	107_L	0.890	1.00
162_T	166_G	0.888	1.00
73_S	76_A	0.877	1.00
154_D	158_R	0.875	1.00
82_P	145_E	0.874	1.00
10_S	14_A	0.872	1.00
137_S	140_S	0.871	1.00
138_V	141_H	0.867	1.00
66_L	69_E	0.860	1.00
92_E	95_V	0.855	1.00
171_S	174_H	0.854	1.00
133_F	137_S	0.850	1.00
136_K	157_A	0.847	1.00
72_A	76_A	0.837	1.00
122_E	126_Q	0.831	1.00
91_D	95_V	0.824	1.00
151_V	156_V	0.818	1.00
88_L	92_E	0.817	1.00
155_H	182_A	0.815	1.00
132_R	154_D	0.814	1.00
8_E	11_E	0.813	1.00
155_H	186_T	0.809	1.00
106_A	110_M	0.802	1.00
39_D	45_T	0.792	1.00
15_E	41_Y	0.792	1.00
17_M	65_Y	0.788	1.00
182_A	186_T	0.787	1.00
125_Q	128_D	0.784	1.00
12_A	43_K	0.780	1.00
29_Y	55_K	0.779	1.00
45_T	50_Y	0.779	1.00
34_I	55_K	0.778	1.00
25_R	102_A	0.776	1.00
15_E	18_Q	0.776	1.00
100_N	103_L	0.775	1.00
130_Y	134_M	0.773	1.00
107_L	110_M	0.773	1.00
23_A	26_E	0.769	1.00
141_H	144_D	0.767	1.00
143_I	146_G	0.764	1.00
9_F	12_A	0.761	1.00
64_D	127_N	0.760	1.00
68_E	72_A	0.756	1.00
16_L	48_V	0.755	1.00
27_H	32_L	0.754	1.00
153_A	157_A	0.745	1.00
121_R	125_Q	0.743	1.00
80_T	84_T	0.743	1.00
87_S	185_R	0.742	1.00
123_R	127_N	0.736	1.00
118_E	122_E	0.730	1.00
118_E	121_R	0.728	1.00
71_V	134_M	0.713	1.00
79_T	84_T	0.711	1.00
18_Q	21_Y	0.711	1.00
133_F	136_K	0.709	1.00
69_E	72_A	0.709	1.00
155_H	159_S	0.707	1.00
116_Y	119_P	0.706	1.00
17_M	21_Y	0.694	1.00
16_L	41_Y	0.692	1.00
82_P	142_G	0.688	1.00
155_H	185_R	0.683	1.00
95_V	180_L	0.681	1.00
72_A	75_R	0.677	1.00
26_E	36_R	0.671	1.00
12_A	47_A	0.670	1.00
8_E	12_A	0.666	1.00
181_A	184_R	0.666	1.00
143_I	148_F	0.665	1.00
130_Y	133_F	0.663	1.00
180_L	184_R	0.654	1.00
41_Y	44_S	0.644	1.00
101_Q	105_V	0.641	1.00
186_T	189_E	0.635	1.00
95_V	184_R	0.634	1.00
182_A	185_R	0.633	1.00
64_D	126_Q	0.629	1.00
170_R	174_H	0.627	1.00
159_S	162_T	0.626	1.00
181_A	185_R	0.624	1.00
90_L	160_L	0.623	1.00
91_D	181_A	0.621	1.00
29_Y	32_L	0.613	1.00
29_Y	56_E	0.612	1.00
76_A	92_E	0.612	1.00
87_S	90_L	0.610	1.00
162_T	165_D	0.606	1.00
35_K	49_H	0.606	1.00
185_R	189_E	0.604	1.00
102_A	105_V	0.603	1.00
139_I	143_I	0.603	1.00
125_Q	129_E	0.600	1.00
34_I	38_A	0.599	1.00
139_I	160_L	0.599	1.00
178_S	182_A	0.594	1.00
79_T	88_L	0.590	1.00
104_S	109_E	0.589	1.00
68_E	127_N	0.586	1.00
139_I	153_A	0.581	1.00
104_S	108_L	0.580	1.00
81_A	85_R	0.578	1.00
119_P	122_E	0.574	1.00
16_L	51_Y	0.570	1.00
24_L	59_L	0.567	1.00
82_P	147_A	0.566	1.00
180_L	183_G	0.565	1.00
155_H	158_R	0.564	1.00
91_D	185_R	0.564	1.00
90_L	93_L	0.563	1.00
144_D	148_F	0.561	1.00
21_Y	69_E	0.558	1.00
184_R	187_A	0.557	1.00
140_S	154_D	0.553	1.00
150_A	153_A	0.550	1.00
98_Q	180_L	0.549	1.00
9_F	51_Y	0.544	1.00
20_T	37_I	0.544	1.00
152_D	156_V	0.540	1.00
12_A	44_S	0.539	1.00
93_L	97_P	0.539	1.00
41_Y	45_T	0.537	1.00
106_A	109_E	0.531	1.00
92_E	96_D	0.531	1.00
127_N	130_Y	0.530	1.00
165_D	170_R	0.530	1.00
127_N	131_T	0.525	1.00
82_P	85_R	0.524	1.00
163_I	166_G	0.523	1.00
35_K	44_S	0.522	1.00
60_A	119_P	0.520	1.00
116_Y	120_F	0.516	1.00
165_D	169_T	0.514	1.00
25_R	105_V	0.513	1.00
69_E	73_S	0.511	1.00
95_V	99_P	0.511	1.00
38_A	44_S	0.510	1.00
155_H	189_E	0.508	1.00
122_E	125_Q	0.507	1.00
128_D	132_R	0.506	1.00
77_V	80_T	0.503	1.00
10_S	13_E	0.503	1.00
69_E	100_N	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3crjA	2	0.9694	100	0.184	Contact Map
2xdnA	2	0.9796	100	0.186	Contact Map
2w53A	2	0.9388	100	0.2	Contact Map
4udsA	2	0.9388	100	0.205	Contact Map
2wuiA	2	0.9541	100	0.206	Contact Map
4kwaA	2	0.9643	100	0.21	Contact Map
2gfnA	2	0.9643	100	0.217	Contact Map
3lhqA	2	1	100	0.219	Contact Map
3lsjA	2	0.9745	100	0.219	Contact Map
4jykA	2	0.9694	100	0.221	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.008 seconds.