Q9HRD0 - HALSA - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

Q9HRD0 - Anion permease

UniProt:	Q9HRD0	Sequences: MISALLGVGLVVAAFVGFNVGGSTTGPAFGPAVGADALSKPTAAGLMTVFFFIGAWTLGRRVVDTLGTELLRQPGIFTLEASIGVLFFIGLALFVGNYAGVPASTSMTAVGAIAGLGLARDALDVAVMGEIVIWWVVAPVIGFWVSLIIGRYFYARLHRRVAMNRTEGALLRVDRTGAIPTVRPAENTNRRELFGVVTVITIGCLMAFSSGTSNIANAIAPLVGSGVVGMNPAILLGCAAVGVGSFTIARRTLETMGSDITELPLTAAIVVASVSATLVIFLSAIGIPASFVVIATVSIVGLGWGRATRPVSVQSAVSGDSDVAVSVGGLAADDPDEAVPAIGEEQPEDIPSAGDLFDPGTTVRVIAMQNLVPIVGTVSAYLAFRFLPIWGF	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	392 (312)
Sequences:	1349 (696)
Seq/√Len:	39.4

ECOLI - PITA PITB
BACSU - PIT SULP
HALSA - Q9HRD0 Q9HHS6 Q9HN03 O54523 Q9HHW5
SULSO - Q97VZ0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
223_V	226_G	6.182	1.00
45_G	49_V	5.908	1.00
18_F	247_T	5.138	1.00
20_V	105_T	4.513	1.00
81_A	116_L	3.842	1.00
252_T	255_T	3.270	1.00
32_A	203_G	3.163	1.00
85_V	109_A	2.988	1.00
133_I	137_V	2.986	1.00
167_E	194_F	2.957	1.00
289_A	294_I	2.931	1.00
282_L	289_A	2.840	1.00
39_S	42_T	2.835	1.00
132_V	136_V	2.767	1.00
271_V	295_A	2.756	1.00
215_I	241_V	2.704	1.00
223_V	227_V	2.698	1.00
36_D	258_S	2.691	1.00
56_W	235_L	2.563	1.00
7_G	11_V	2.529	1.00
160_R	166_T	2.474	1.00
112_A	204_C	2.316	1.00
256_M	296_T	2.227	0.99
51_F	210_S	2.200	0.99
127_V	130_E	2.193	0.99
243_V	247_T	2.182	0.99
135_W	139_P	2.139	0.99
71_L	117_G	2.076	0.99
16_V	89_I	2.075	0.99
18_F	248_I	2.021	0.99
91_L	95_V	1.913	0.98
17_G	218_A	1.891	0.98
219_I	237_G	1.863	0.98
138_A	293_V	1.824	0.98
95_V	99_A	1.811	0.98
114_A	128_M	1.780	0.97
84_G	88_F	1.769	0.97
256_M	299_I	1.765	0.97
110_V	131_I	1.733	0.97
310_P	313_V	1.708	0.97
152_Y	156_R	1.697	0.97
44_A	246_F	1.661	0.96
152_Y	174_D	1.655	0.96
148_I	152_Y	1.647	0.96
35_A	93_L	1.644	0.96
231_N	235_L	1.637	0.96
15_F	94_F	1.630	0.96
112_A	283_S	1.628	0.96
5_L	83_I	1.626	0.96
31_P	295_A	1.611	0.95
291_F	294_I	1.609	0.95
51_F	245_S	1.607	0.95
27_P	210_S	1.602	0.95
37_A	196_V	1.601	0.95
107_M	293_V	1.587	0.95
50_F	204_C	1.571	0.95
85_V	89_I	1.560	0.94
199_V	272_A	1.533	0.94
146_S	298_S	1.532	0.94
56_W	238_C	1.523	0.94
126_A	133_I	1.502	0.93
153_F	157_L	1.500	0.93
199_V	268_A	1.469	0.92
147_L	305_G	1.463	0.92
224_G	227_V	1.459	0.92
24_T	292_V	1.444	0.92
46_L	229_G	1.444	0.92
274_V	298_S	1.433	0.92
283_S	286_G	1.421	0.91
38_L	200_I	1.419	0.91
123_L	152_Y	1.417	0.91
89_I	279_V	1.409	0.91
53_I	57_T	1.407	0.91
31_P	271_V	1.403	0.91
91_L	243_V	1.382	0.90
214_N	292_V	1.381	0.90
108_T	293_V	1.372	0.90
66_L	220_A	1.371	0.90
5_L	79_L	1.360	0.89
149_I	270_V	1.349	0.89
135_W	143_F	1.346	0.89
6_L	180_P	1.345	0.89
14_A	81_A	1.309	0.87
53_I	208_F	1.304	0.87
133_I	136_V	1.303	0.87
234_I	238_C	1.302	0.87
83_I	176_T	1.298	0.87
40_K	253_L	1.297	0.87
135_W	221_P	1.287	0.86
18_F	94_F	1.282	0.86
169_A	173_V	1.276	0.86
134_W	138_A	1.270	0.86
38_L	42_T	1.256	0.85
19_N	94_F	1.249	0.85
32_A	272_A	1.247	0.85
238_C	241_V	1.246	0.85
17_G	22_G	1.244	0.84
150_G	301_G	1.242	0.84
105_T	216_A	1.231	0.84
15_F	19_N	1.220	0.83
85_V	90_G	1.215	0.83
43_A	303_G	1.213	0.83
14_A	240_A	1.198	0.82
151_R	155_A	1.185	0.81
68_T	112_A	1.184	0.81
11_V	49_V	1.182	0.81
137_V	287_I	1.172	0.81
95_V	161_V	1.164	0.80
248_I	251_R	1.157	0.80
271_V	299_I	1.155	0.80
13_A	216_A	1.146	0.79
47_M	96_G	1.145	0.79
68_T	229_G	1.138	0.79
50_F	57_T	1.137	0.79
154_Y	306_R	1.134	0.78
171_L	175_R	1.125	0.78
128_M	131_I	1.116	0.77
56_W	231_N	1.115	0.77
149_I	201_T	1.109	0.77
24_T	210_S	1.108	0.77
263_L	282_L	1.108	0.77
16_V	34_G	1.106	0.77
151_R	305_G	1.093	0.76
68_T	157_L	1.090	0.76
36_D	165_R	1.087	0.75
172_R	183_R	1.079	0.75
129_G	133_I	1.079	0.75
7_G	228_V	1.074	0.75
148_I	177_G	1.061	0.74
85_V	220_A	1.060	0.74
136_V	140_V	1.057	0.73
69_E	286_G	1.054	0.73
268_A	272_A	1.051	0.73
24_T	107_M	1.029	0.71
142_G	198_T	1.027	0.71
31_P	150_G	1.023	0.71
52_F	56_W	1.009	0.70
108_T	119_A	1.005	0.69
92_A	103_A	1.002	0.69
215_I	237_G	0.997	0.69
172_R	177_G	0.995	0.69
80_E	280_I	0.995	0.69
58_L	238_C	0.992	0.68
206_M	263_L	0.992	0.68
247_T	250_R	0.992	0.68
9_G	250_R	0.990	0.68
35_A	76_I	0.984	0.68
213_S	291_F	0.983	0.68
179_I	182_V	0.977	0.67
217_N	221_P	0.974	0.67
168_G	175_R	0.973	0.67
192_E	265_L	0.968	0.67
38_L	146_S	0.965	0.66
31_P	272_A	0.963	0.66
149_I	277_T	0.958	0.66
70_L	220_A	0.958	0.66
24_T	27_P	0.957	0.66
261_T	279_V	0.956	0.66
33_V	43_A	0.955	0.65
15_F	90_G	0.953	0.65
11_V	14_A	0.946	0.65
158_H	188_T	0.943	0.64
112_A	116_L	0.942	0.64
172_R	181_T	0.939	0.64
52_F	192_E	0.932	0.64
47_M	245_S	0.927	0.63
200_I	289_A	0.925	0.63
200_I	279_V	0.924	0.63
15_F	253_L	0.922	0.63
4_A	7_G	0.921	0.63
41_P	45_G	0.915	0.62
100_G	301_G	0.913	0.62
24_T	213_S	0.913	0.62
267_A	306_R	0.905	0.61
35_A	63_V	0.901	0.61
14_A	236_L	0.898	0.61
204_C	277_T	0.896	0.60
162_A	165_R	0.893	0.60
108_T	202_I	0.893	0.60
117_G	121_D	0.892	0.60
184_P	190_R	0.892	0.60
89_I	269_I	0.887	0.60
85_V	120_R	0.882	0.59
15_F	248_I	0.881	0.59
68_T	132_V	0.881	0.59
136_V	181_T	0.881	0.59
23_S	103_A	0.880	0.59
230_M	281_F	0.880	0.59
98_Y	248_I	0.870	0.58
109_A	216_A	0.870	0.58
71_L	80_E	0.866	0.58
180_P	183_R	0.864	0.58
187_N	190_R	0.863	0.58
215_I	221_P	0.863	0.58
128_M	132_V	0.860	0.57
25_T	241_V	0.849	0.56
66_L	85_V	0.849	0.56
30_G	34_G	0.846	0.56
31_P	202_I	0.845	0.56
169_A	172_R	0.845	0.56
106_S	292_V	0.844	0.56
214_N	217_N	0.844	0.56
14_A	179_I	0.840	0.56
312_S	315_S	0.840	0.56
10_L	236_L	0.839	0.55
23_S	97_N	0.838	0.55
34_G	240_A	0.838	0.55
122_A	241_V	0.837	0.55
27_P	51_F	0.837	0.55
104_S	138_A	0.837	0.55
206_M	294_I	0.835	0.55
204_C	254_E	0.834	0.55
12_V	280_I	0.831	0.55
158_H	266_T	0.831	0.55
124_D	236_L	0.828	0.54
29_F	57_T	0.828	0.54
68_T	127_V	0.827	0.54
158_H	163_M	0.825	0.54
140_V	228_V	0.824	0.54
311_V	315_S	0.824	0.54
24_T	214_N	0.820	0.54
46_L	49_V	0.818	0.54
66_L	110_V	0.818	0.54
6_L	189_N	0.814	0.53
94_F	209_S	0.814	0.53
114_A	118_L	0.811	0.53
210_S	214_N	0.810	0.53
152_Y	155_A	0.810	0.53
35_A	251_R	0.806	0.52
9_G	83_I	0.806	0.52
65_T	69_E	0.805	0.52
38_L	272_A	0.801	0.52
95_V	162_A	0.797	0.52
29_F	38_L	0.797	0.52
27_P	214_N	0.796	0.52
11_V	165_R	0.789	0.51
168_G	183_R	0.789	0.51
154_Y	159_R	0.787	0.51
121_D	142_G	0.785	0.51
118_L	136_V	0.784	0.50
146_S	270_V	0.782	0.50
96_G	103_A	0.782	0.50
117_G	218_A	0.781	0.50
175_R	182_V	0.781	0.50
205_L	212_T	0.779	0.50
136_V	301_G	0.776	0.50
165_R	173_V	0.774	0.50
68_T	275_S	0.774	0.50
10_L	222_L	0.769	0.49
24_T	51_F	0.767	0.49
107_M	292_V	0.766	0.49
74_P	77_F	0.765	0.49
200_I	238_C	0.765	0.49
176_T	242_G	0.762	0.48
124_D	141_I	0.758	0.48
263_L	271_V	0.757	0.48
32_A	125_V	0.756	0.48
107_M	111_G	0.753	0.48
62_V	253_L	0.751	0.47
50_F	53_I	0.745	0.47
129_G	132_V	0.745	0.47
113_I	222_L	0.744	0.47
111_G	135_W	0.742	0.47
184_P	256_M	0.741	0.47
162_A	169_A	0.741	0.47
6_L	233_A	0.740	0.46
179_I	183_R	0.733	0.46
25_T	245_S	0.732	0.46
48_T	242_G	0.730	0.46
146_S	274_V	0.728	0.45
16_V	30_G	0.727	0.45
71_L	154_Y	0.725	0.45
166_T	169_A	0.725	0.45
176_T	229_G	0.724	0.45
28_A	279_V	0.724	0.45
215_I	240_A	0.722	0.45
180_P	274_V	0.719	0.45
17_G	287_I	0.714	0.44
13_A	70_L	0.714	0.44
141_I	287_I	0.710	0.44
50_F	256_M	0.708	0.44
142_G	294_I	0.707	0.43
132_V	151_R	0.706	0.43
201_T	266_T	0.706	0.43
233_A	238_C	0.706	0.43
191_R	266_T	0.705	0.43
66_L	73_Q	0.704	0.43
30_G	113_I	0.702	0.43
171_L	273_S	0.701	0.43
38_L	46_L	0.698	0.43
206_M	216_A	0.698	0.43
8_V	160_R	0.694	0.42
138_A	141_I	0.694	0.42
37_A	50_F	0.694	0.42
148_I	201_T	0.692	0.42
27_P	292_V	0.692	0.42
77_F	114_A	0.691	0.42
96_G	245_S	0.691	0.42
208_F	211_G	0.690	0.42
252_T	296_T	0.689	0.42
155_A	173_V	0.687	0.42
91_L	233_A	0.687	0.42
279_V	283_S	0.686	0.42
270_V	274_V	0.684	0.41
228_V	231_N	0.684	0.41
137_V	282_L	0.680	0.41
19_N	91_L	0.679	0.41
17_G	213_S	0.678	0.41
222_L	306_R	0.678	0.41
172_R	175_R	0.676	0.41
60_R	301_G	0.675	0.41
155_A	313_V	0.672	0.40
160_R	251_R	0.671	0.40
116_L	307_A	0.666	0.40
105_T	136_V	0.664	0.40
82_S	113_I	0.664	0.40
97_N	251_R	0.664	0.40
29_F	196_V	0.663	0.40
25_T	249_A	0.662	0.40
36_D	64_D	0.661	0.39
212_T	300_V	0.661	0.39
156_R	160_R	0.659	0.39
14_A	311_V	0.657	0.39
158_H	310_P	0.656	0.39
221_P	237_G	0.654	0.39
254_E	259_D	0.652	0.39
30_G	208_F	0.651	0.39
242_G	245_S	0.650	0.38
37_A	219_I	0.645	0.38
153_F	294_I	0.643	0.38
84_G	256_M	0.640	0.38
229_G	285_I	0.637	0.37
79_L	227_V	0.633	0.37
6_L	79_L	0.633	0.37
22_G	35_A	0.633	0.37
11_V	228_V	0.632	0.37
189_N	192_E	0.630	0.37
214_N	291_F	0.630	0.37
252_T	256_M	0.629	0.37
178_A	182_V	0.629	0.37
20_V	216_A	0.628	0.37
263_L	299_I	0.628	0.37
216_A	292_V	0.627	0.37
277_T	294_I	0.625	0.36
71_L	116_L	0.623	0.36
87_F	129_G	0.621	0.36
191_R	222_L	0.620	0.36
56_W	262_E	0.620	0.36
36_D	164_N	0.615	0.35
51_F	93_L	0.611	0.35
137_V	187_N	0.610	0.35
95_V	298_S	0.609	0.35
36_D	282_L	0.606	0.35
141_I	173_V	0.606	0.35
93_L	105_T	0.606	0.35
60_R	284_A	0.606	0.35
215_I	282_L	0.606	0.35
12_V	90_G	0.605	0.35
27_P	245_S	0.605	0.35
175_R	179_I	0.605	0.35
31_P	201_T	0.603	0.35
121_D	291_F	0.603	0.35
154_Y	181_T	0.601	0.34
18_F	76_I	0.598	0.34
48_T	142_G	0.597	0.34
52_F	242_G	0.593	0.34
102_P	292_V	0.592	0.34
147_L	207_A	0.588	0.33
173_V	177_G	0.588	0.33
153_F	174_D	0.588	0.33
55_A	86_L	0.588	0.33
101_V	199_V	0.587	0.33
144_W	298_S	0.587	0.33
275_S	302_L	0.587	0.33
45_G	169_A	0.586	0.33
167_E	175_R	0.586	0.33
167_E	279_V	0.586	0.33
30_G	131_I	0.585	0.33
120_R	128_M	0.579	0.33
35_A	255_T	0.578	0.32
17_G	118_L	0.577	0.32
260_I	279_V	0.577	0.32
36_D	173_V	0.576	0.32
36_D	68_T	0.575	0.32
205_L	277_T	0.573	0.32
195_G	269_I	0.572	0.32
28_A	197_V	0.570	0.32
9_G	298_S	0.569	0.32
298_S	314_Q	0.568	0.32
283_S	293_V	0.567	0.32
29_F	260_I	0.566	0.32
69_E	72_R	0.566	0.32
251_R	254_E	0.565	0.31
50_F	198_T	0.565	0.31
22_G	278_L	0.561	0.31
224_G	281_F	0.561	0.31
212_T	259_D	0.561	0.31
147_L	307_A	0.560	0.31
66_L	284_A	0.560	0.31
149_I	310_P	0.559	0.31
93_L	233_A	0.559	0.31
78_T	243_V	0.557	0.31
129_G	209_S	0.557	0.31
269_I	291_F	0.553	0.31
23_S	51_F	0.553	0.31
16_V	86_L	0.552	0.30
93_L	97_N	0.549	0.30
116_L	119_A	0.547	0.30
58_L	199_V	0.545	0.30
157_L	195_G	0.545	0.30
37_A	260_I	0.544	0.30
7_G	193_L	0.542	0.30
307_A	312_S	0.542	0.30
53_I	131_I	0.542	0.30
36_D	262_E	0.541	0.30
71_L	109_A	0.541	0.30
309_R	313_V	0.540	0.30
135_W	237_G	0.539	0.29
209_S	212_T	0.538	0.29
30_G	299_I	0.537	0.29
89_I	282_L	0.537	0.29
68_T	241_V	0.535	0.29
110_V	286_G	0.535	0.29
38_L	242_G	0.535	0.29
31_P	199_V	0.534	0.29
198_T	269_I	0.534	0.29
51_F	96_G	0.534	0.29
232_P	270_V	0.534	0.29
94_F	198_T	0.533	0.29
135_W	217_N	0.532	0.29
143_F	301_G	0.531	0.29
85_V	166_T	0.531	0.29
45_G	173_V	0.531	0.29
104_S	195_G	0.531	0.29
171_L	182_V	0.530	0.29
64_D	67_G	0.529	0.29
203_G	276_A	0.527	0.29
30_G	256_M	0.527	0.29
13_A	83_I	0.526	0.28
119_A	165_R	0.526	0.28
71_L	123_L	0.524	0.28
164_N	259_D	0.522	0.28
145_V	162_A	0.521	0.28
250_R	254_E	0.521	0.28
19_N	32_A	0.520	0.28
272_A	295_A	0.520	0.28
208_F	222_L	0.520	0.28
249_A	257_G	0.518	0.28
206_M	280_I	0.517	0.28
165_R	168_G	0.517	0.28
192_E	267_A	0.516	0.28
108_T	280_I	0.515	0.28
261_T	303_G	0.513	0.28
237_G	241_V	0.512	0.27
45_G	165_R	0.512	0.27
59_G	135_W	0.511	0.27
153_F	230_M	0.510	0.27
158_H	313_V	0.509	0.27
28_A	94_F	0.509	0.27
73_Q	114_A	0.508	0.27
252_T	291_F	0.508	0.27
52_F	206_M	0.508	0.27
235_L	243_V	0.507	0.27
9_G	171_L	0.504	0.27
165_R	177_G	0.503	0.27
70_L	243_V	0.502	0.27
130_E	285_I	0.500	0.27
5_L	11_V	0.500	0.27

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1ldfA	3	0.5995	77.4	0.964	Contact Map
2b6oA	6	0.5893	75.8	0.965	Contact Map
3d9sA	3	0.5816	65.5	0.967	Contact Map
4oj2X	3	0.6122	63.7	0.968	Contact Map
3c02A	3	0.5867	54.5	0.97	Contact Map
1j4nA	4	0.6224	44.1	0.971	Contact Map
4c7rA	3	0.7781	43.1	0.972	Contact Map
4nefA	4	0.4235	24.5	0.975	Contact Map
3pe5A	1	0	23.2	0.975	Contact Map
3fymA	1	0.1837	21.9	0.976	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0104 seconds.