GREMLIN Database
Q9HRA6 - Plastocyanin homology
UniProt: Q9HRA6 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 149 (127)
Sequences: 466 (374)
Seq/√Len: 33.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
18_L21_C3.9601.00
2_H5_A2.8261.00
77_Y137_E2.7171.00
62_V123_L2.5981.00
8_A12_T2.4401.00
54_H145_L2.3520.99
56_L123_L2.3390.99
26_V29_S2.2290.99
133_C136_H2.2000.99
58_A126_P2.1720.99
54_H60_D1.9930.98
62_V131_Y1.9280.97
75_T134_I1.8180.96
66_N117_A1.7830.96
66_N73_T1.7590.95
64_W145_L1.7300.95
53_T146_V1.7280.95
27_S30_D1.6310.93
66_N113_I1.6200.93
66_N70_R1.6130.93
7_L16_G1.6100.93
12_T16_G1.6040.92
72_H133_C1.5910.92
56_L145_L1.5700.92
113_I117_A1.5110.90
25_S28_K1.5070.90
34_G39_G1.5060.90
81_L84_G1.4930.89
43_Q48_G1.4920.89
134_I142_R1.4900.89
55_Q126_P1.4320.87
132_F137_E1.3870.86
42_P46_V1.3780.85
18_L22_I1.3690.85
43_Q46_V1.3530.84
54_H64_W1.3140.82
135_P140_G1.3130.82
53_T144_K1.3090.82
128_E146_V1.3040.82
42_P145_L1.2990.82
134_I137_E1.2970.82
38_N47_E1.2920.81
117_A138_G1.2770.80
76_A79_S1.2740.80
5_A8_A1.2720.80
64_W131_Y1.2580.79
64_W123_L1.2410.79
78_G105_D1.2410.79
61_T122_T1.2360.78
128_E142_R1.2140.77
47_E139_A1.2090.77
21_C126_P1.1920.76
35_M39_G1.1870.75
56_L74_V1.1720.74
130_Y144_K1.1670.74
66_N75_T1.1590.74
40_F43_Q1.1550.73
105_D109_G1.1440.73
10_G15_V1.1200.71
8_A11_T1.1180.71
20_G60_D1.1150.71
83_E119_Y1.0860.69
11_T14_S1.0800.68
39_G43_Q1.0780.68
77_Y132_F1.0750.68
51_M72_H1.0750.68
61_T120_E1.0730.68
127_G147_V1.0500.66
79_S132_F1.0500.66
55_Q146_V1.0410.65
71_N112_N1.0400.65
21_C58_A1.0170.63
38_N45_P1.0150.63
47_E69_S1.0000.62
46_V70_R0.9960.62
123_L145_L0.9900.61
50_D130_Y0.9660.59
73_T111_G0.9510.58
132_F138_G0.9490.58
70_R73_T0.9440.58
55_Q128_E0.9330.57
79_S82_P0.9110.55
23_G29_S0.9080.55
75_T111_G0.9070.54
71_N116_G0.9030.54
130_Y146_V0.8970.54
23_G128_E0.8940.53
5_A21_C0.8550.50
2_H9_G0.8510.50
47_E116_G0.8400.49
73_T134_I0.8320.48
8_A146_V0.8280.48
81_L117_A0.8280.48
121_V129_Y0.8270.48
135_P141_M0.8260.48
55_Q144_K0.8120.47
49_E73_T0.8040.46
73_T77_Y0.7980.45
5_A18_L0.7970.45
114_S117_A0.7810.44
7_L11_T0.7750.44
36_V54_H0.7710.43
10_G63_T0.7620.42
48_G52_A0.7590.42
27_S31_Y0.7560.42
14_S31_Y0.7510.42
9_G12_T0.7460.41
76_A121_V0.7370.40
130_Y142_R0.7350.40
35_M40_F0.7350.40
121_V124_T0.7330.40
129_Y132_F0.7270.40
34_G115_P0.7260.40
25_S29_S0.7190.39
64_W74_V0.7170.39
109_G112_N0.7160.39
32_D56_L0.7160.39
35_M38_N0.7140.39
47_E115_P0.7040.38
102_A105_D0.7010.38
42_P48_G0.6900.37
75_T132_F0.6750.36
18_L30_D0.6680.35
18_L58_A0.6680.35
109_G113_I0.6670.35
65_A139_A0.6670.35
76_A80_G0.6650.35
16_G19_A0.6600.34
46_V145_L0.6580.34
10_G13_L0.6570.34
62_V143_G0.6560.34
13_L143_G0.6560.34
37_S125_V0.6510.34
82_P119_Y0.6500.34
103_W119_Y0.6490.34
11_T16_G0.6480.34
68_G140_G0.6460.33
43_Q67_T0.6420.33
73_T135_P0.6380.33
64_W121_V0.6340.32
57_T60_D0.6220.32
8_A17_V0.6220.32
25_S54_H0.6190.31
68_G109_G0.6190.31
28_K32_D0.6100.31
104_Q132_F0.6100.31
3_R7_L0.6090.31
34_G43_Q0.6050.30
56_L60_D0.5960.30
103_W139_A0.5960.30
3_R6_F0.5950.30
20_G68_G0.5910.29
136_H141_M0.5910.29
64_W119_Y0.5900.29
85_A121_V0.5840.29
16_G24_P0.5840.29
59_G133_C0.5810.29
21_C56_L0.5790.29
5_A9_G0.5780.29
11_T142_R0.5760.28
47_E146_V0.5750.28
2_H17_V0.5730.28
80_G84_G0.5720.28
60_D118_T0.5700.28
69_S113_I0.5680.28
64_W68_G0.5670.28
34_G41_V0.5610.27
114_S119_Y0.5590.27
14_S56_L0.5520.27
28_K31_Y0.5510.27
78_G81_L0.5440.26
80_G119_Y0.5430.26
70_R113_I0.5410.26
80_G132_F0.5380.26
59_G136_H0.5370.26
51_M145_L0.5280.25
68_G85_A0.5270.25
38_N41_V0.5260.25
13_L124_T0.5230.25
128_E144_K0.5210.25
15_V134_I0.5200.25
53_T60_D0.5200.25
72_H136_H0.5190.25
68_G144_K0.5150.24
6_F33_I0.5150.24
13_L110_G0.5090.24
109_G117_A0.5070.24
82_P129_Y0.5040.24
24_P56_L0.5030.24
59_G127_G0.5000.24
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3c75A 1 0.6846 99.9 0.455 Contact Map
1iuzA 1 0.6577 99.8 0.567 Contact Map
1bypA 1 0.6644 99.8 0.567 Contact Map
3ef4A 1 0.6174 99.8 0.568 Contact Map
1pazA 1 0.6309 99.8 0.569 Contact Map
1pmyA 1 0.6309 99.8 0.571 Contact Map
3erxA 3 0.6309 99.7 0.573 Contact Map
2pltA 1 0.6577 99.7 0.574 Contact Map
1pcsA 2 0.6577 99.7 0.575 Contact Map
2ov0A 1 0.7047 99.7 0.577 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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