GREMLIN Database
RS3A - 30S ribosomal protein S3Ae
UniProt: Q9HRA5 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 206 (192)
Sequences: 455 (290)
Seq/√Len: 21.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
85_R89_R6.8441.00
66_I74_A3.9891.00
12_E35_E3.4461.00
115_I141_V3.3921.00
54_D57_D3.1421.00
81_A184_A2.8890.99
45_I66_I2.5130.98
164_S167_Y2.5010.98
35_E39_Q2.4840.98
113_V153_L2.4680.97
153_L157_I2.4510.97
115_I153_L2.4360.97
7_S10_D2.4090.97
17_T28_E2.3730.97
157_I184_A2.3330.96
43_R109_D2.2680.96
116_Q185_T2.2470.96
121_T125_A2.1590.94
165_A169_E2.0410.93
89_R92_V2.0360.93
17_T31_E1.9600.91
137_M166_I1.9230.90
43_R114_R1.8540.88
125_A129_Q1.8080.87
145_G153_L1.7880.86
114_R134_R1.7470.85
43_R134_R1.7230.84
65_Q79_V1.6880.83
135_R138_I1.6730.83
4_R33_L1.6500.82
149_T152_A1.6430.81
88_Q118_V1.6260.81
91_L96_S1.6240.81
13_K21_P1.5830.79
7_S93_R1.5790.79
108_T149_T1.5770.79
117_P181_V1.5120.75
118_V130_Q1.5000.75
135_R139_D1.4800.74
127_Q131_H1.3940.69
65_Q130_Q1.3880.69
37_P74_A1.3870.69
38_D41_Y1.3830.69
106_L112_R1.3780.68
117_P137_M1.3700.68
111_Y190_P1.3670.68
20_A42_D1.3640.67
83_L180_E1.3480.67
62_L153_L1.3340.66
17_T40_V1.3320.66
50_S130_Q1.3200.65
162_L181_V1.3100.64
144_A156_S1.3090.64
109_D134_R1.3070.64
36_E94_R1.3070.64
65_Q189_H1.3010.64
14_R36_E1.2790.62
129_Q166_I1.2430.60
137_M141_V1.2350.60
32_T111_Y1.2350.60
107_T111_Y1.2290.59
153_L160_G1.2280.59
39_Q74_A1.2280.59
65_Q89_R1.2240.59
125_A130_Q1.1910.57
8_K18_V1.1890.57
137_M179_V1.1870.56
65_Q97_S1.1840.56
45_I174_Y1.1520.54
43_R66_I1.1500.54
89_R147_E1.1360.53
117_P141_V1.1250.52
186_L189_H1.1250.52
139_D144_A1.1110.51
167_Y178_R1.1070.51
83_L148_R1.1040.51
101_V138_I1.1020.51
136_T139_D1.0810.49
189_H192_E1.0760.49
116_Q182_E1.0750.49
32_T40_V1.0650.48
46_Q61_K1.0380.47
33_L172_T1.0330.46
18_V29_L1.0090.45
69_V73_S0.9990.44
129_Q133_I0.9970.44
133_I137_M0.9930.44
97_S130_Q0.9930.44
24_F49_L0.9760.43
31_E167_Y0.9740.42
60_I81_A0.9730.42
66_I115_I0.9700.42
160_G178_R0.9650.42
138_I142_E0.9570.41
82_E103_V0.9550.41
91_L160_G0.9520.41
49_L120_Y0.9450.41
120_Y182_E0.9440.41
81_A157_I0.9420.40
15_W21_P0.9380.40
33_L65_Q0.9350.40
64_F130_Q0.9300.40
49_L91_L0.9280.39
16_Y37_P0.9260.39
29_L170_A0.9260.39
48_A59_N0.9230.39
69_V74_A0.9220.39
62_L157_I0.9170.39
100_A182_E0.9160.39
163_S176_L0.9110.38
97_S139_D0.9100.38
19_L28_E0.9040.38
53_R57_D0.9030.38
104_T110_D0.9020.38
109_D114_R0.9010.38
58_N93_R0.8980.38
16_Y125_A0.8940.37
78_F86_D0.8920.37
85_R90_S0.8890.37
101_V176_L0.8880.37
66_I177_R0.8840.37
115_I145_G0.8840.37
114_R186_L0.8840.37
17_T72_D0.8810.37
87_Y94_R0.8810.37
22_E26_R0.8800.36
93_R149_T0.8760.36
141_V169_E0.8690.36
5_S44_T0.8670.36
18_V155_N0.8640.36
45_I170_A0.8530.35
46_Q90_S0.8490.35
95_G116_Q0.8420.34
10_D33_L0.8410.34
125_A174_Y0.8390.34
45_I52_V0.8380.34
50_S53_R0.8320.34
55_G91_L0.8220.33
48_A77_Q0.8180.33
52_V68_D0.8160.33
164_S170_A0.8120.32
16_Y175_P0.8100.32
140_L166_I0.8100.32
27_A146_E0.8080.32
24_F32_T0.8040.32
64_F190_P0.8010.32
64_F102_T0.7970.32
45_I152_A0.7940.31
52_V115_I0.7890.31
100_A120_Y0.7820.31
88_Q173_I0.7790.31
119_A176_L0.7760.30
54_D191_E0.7730.30
69_V92_V0.7680.30
43_R121_T0.7670.30
29_L83_L0.7660.30
44_T65_Q0.7650.30
85_R138_I0.7610.30
184_A188_A0.7530.29
87_Y180_E0.7530.29
39_Q176_L0.7530.29
65_Q93_R0.7520.29
11_Q108_T0.7470.29
112_R158_I0.7430.29
22_E187_E0.7430.29
63_T146_E0.7400.28
80_Q134_R0.7400.28
64_F76_T0.7380.28
62_L113_V0.7350.28
114_R124_Q0.7330.28
70_G73_S0.7260.28
61_K157_I0.7180.27
49_L111_Y0.7180.27
27_A34_A0.7160.27
7_S11_Q0.7140.27
51_D114_R0.7130.27
58_N96_S0.7130.27
113_V128_S0.7100.27
155_N166_I0.7080.27
112_R187_E0.7040.26
112_R139_D0.7040.26
68_D193_V0.7020.26
46_Q174_Y0.6940.26
119_A141_V0.6920.26
37_P69_V0.6910.26
181_V190_P0.6880.26
96_S120_Y0.6830.25
166_I182_E0.6810.25
54_D128_S0.6780.25
112_R186_L0.6780.25
5_S45_I0.6720.25
17_T56_G0.6710.25
165_A168_D0.6690.25
66_I88_Q0.6680.25
36_E44_T0.6660.25
30_G166_I0.6630.24
55_G58_N0.6610.24
39_Q138_I0.6610.24
40_V63_T0.6590.24
55_G178_R0.6590.24
136_T141_V0.6590.24
18_V76_T0.6590.24
156_S161_R0.6490.24
33_L58_N0.6490.24
9_Q116_Q0.6410.23
4_R50_S0.6400.23
64_F88_Q0.6390.23
11_Q36_E0.6340.23
33_L146_E0.6300.23
106_L156_S0.6290.23
49_L180_E0.6250.23
4_R12_E0.6250.23
50_S100_A0.6220.22
95_G98_K0.6210.22
55_G62_L0.6200.22
103_V138_I0.6170.22
39_Q151_E0.6160.22
141_V189_H0.6150.22
79_V157_I0.6130.22
5_S14_R0.6110.22
44_T143_E0.6110.22
25_D102_T0.6100.22
61_K84_T0.6080.22
54_D179_V0.6060.22
20_A64_F0.6030.22
102_T115_I0.6020.22
14_R17_T0.6010.21
80_Q86_D0.6000.21
51_D73_S0.5990.21
91_L98_K0.5970.21
16_Y71_S0.5940.21
88_Q166_I0.5890.21
104_T187_E0.5870.21
105_V145_G0.5850.21
144_A148_R0.5830.21
140_L181_V0.5800.21
7_S194_H0.5780.20
51_D70_G0.5750.20
48_A74_A0.5750.20
159_E165_A0.5720.20
90_S120_Y0.5680.20
110_D149_T0.5660.20
80_Q186_L0.5660.20
46_Q179_V0.5620.20
54_D108_T0.5610.20
133_I174_Y0.5610.20
113_V143_E0.5600.20
140_L191_E0.5580.20
38_D67_D0.5560.20
41_Y69_V0.5540.19
6_V112_R0.5520.19
30_G133_I0.5510.19
83_L118_V0.5510.19
32_T52_V0.5490.19
124_Q133_I0.5490.19
167_Y185_T0.5440.19
93_R99_V0.5440.19
148_R156_S0.5430.19
75_S158_I0.5380.19
15_W134_R0.5370.19
152_A173_I0.5370.19
52_V79_V0.5350.19
57_D91_L0.5330.19
37_P41_Y0.5330.19
92_V125_A0.5300.18
22_E72_D0.5280.18
46_Q190_P0.5270.18
34_A37_P0.5250.18
56_G62_L0.5250.18
11_Q94_R0.5230.18
82_E140_L0.5220.18
154_L194_H0.5200.18
70_G79_V0.5160.18
135_R181_V0.5150.18
58_N83_L0.5140.18
14_R82_E0.5140.18
20_A186_L0.5130.18
192_E195_E0.5110.18
110_D130_Q0.5100.18
61_K123_K0.5090.18
48_A180_E0.5090.18
66_I146_E0.5080.18
29_L65_Q0.5070.18
57_D93_R0.5070.18
98_K118_V0.5060.18
113_V133_I0.5040.17
72_D115_I0.5010.17
139_D143_E0.5000.17
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3j38B 1 0.9757 100 0.033 Contact Map
4w23B 1 0.9563 100 0.034 Contact Map
3j7aB 1 0.9369 100 0.035 Contact Map
3j60B 1 0.9417 100 0.038 Contact Map
3zey0 1 0.966 100 0.039 Contact Map
4ujpC 1 0.9563 100 0.041 Contact Map
4bpe4 1 0.9126 100 0.044 Contact Map
3j20A 1 0.9175 100 0.063 Contact Map
3bk6A 3 0.5728 14.1 0.964 Contact Map
1gd8A 1 0.2573 11.2 0.965 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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