GREMLIN Database
RS15 - 30S ribosomal protein S15
UniProt: Q9HRA2 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 155 (149)
Sequences: 379 (205)
Seq/√Len: 16.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
102_L122_T6.9061.00
71_T78_I4.8221.00
73_K81_A3.9961.00
138_L142_F3.0220.99
2_A8_R2.6460.97
103_H146_Y2.5280.96
5_H102_L2.4860.95
102_L115_N2.4430.95
37_V78_I2.4350.95
16_R66_D2.2850.93
26_S70_A2.2080.91
123_Q144_Y2.1830.91
150_R153_I2.1230.89
57_E67_V1.8990.83
88_L137_K1.8390.81
26_S65_P1.8230.81
34_E38_V1.7800.79
36_R136_D1.7400.77
67_V78_I1.7190.76
1_M5_H1.7070.76
110_G125_K1.6890.75
28_V64_V1.6250.72
31_D34_E1.6010.71
148_T152_I1.6000.71
122_T125_K1.5810.70
38_V82_H1.5790.70
42_E84_A1.5540.69
36_R39_E1.5510.68
43_Q124_S1.5480.68
17_P41_A1.5210.67
98_K110_G1.4990.66
26_S29_D1.4490.63
48_S74_K1.4260.62
99_A144_Y1.4180.61
75_V102_L1.4000.60
119_L123_Q1.3820.59
34_E136_D1.3770.59
139_D142_F1.3510.57
101_R118_A1.3110.55
48_S90_E1.3070.55
35_E39_E1.2980.54
55_R90_E1.2440.51
82_H137_K1.2390.51
26_S32_A1.2340.51
107_E116_K1.2210.50
37_V71_T1.2000.49
17_P127_R1.1830.47
21_E33_I1.1690.47
38_V87_E1.1590.46
32_A134_R1.1570.46
116_K120_Q1.1520.46
65_P117_R1.1310.44
26_S69_L1.1180.44
57_E136_D1.1160.44
104_E109_N1.1060.43
57_E65_P1.1010.43
87_E153_I1.0980.43
41_A86_P1.0950.42
109_N146_Y1.0940.42
36_R40_L1.0860.42
40_L67_V1.0620.40
88_L153_I1.0600.40
104_E107_E1.0540.40
12_S87_E1.0530.40
143_A151_E1.0520.40
97_E113_H1.0500.40
12_S34_E1.0400.39
93_R97_E1.0360.39
9_R124_S1.0340.39
7_R16_R1.0300.39
100_V153_I1.0130.38
99_A123_Q1.0090.37
29_D38_V1.0090.37
2_A7_R1.0060.37
12_S141_E0.9980.37
48_S69_L0.9940.37
104_E151_E0.9920.36
103_H120_Q0.9880.36
130_A142_F0.9820.36
114_Q118_A0.9740.36
126_I144_Y0.9700.35
42_E142_F0.9690.35
22_P28_V0.9350.33
145_S148_T0.9280.33
91_D133_Y0.9250.33
1_M4_M0.9240.33
65_P125_K0.9220.33
37_V50_I0.9200.33
142_F151_E0.9080.32
123_Q126_I0.9010.32
9_R131_D0.8740.30
98_K114_Q0.8720.30
6_T135_G0.8700.30
8_R125_K0.8680.30
77_E80_E0.8670.30
105_H112_D0.8620.30
144_Y149_A0.8500.29
67_V111_Q0.8490.29
18_T80_E0.8460.29
80_E85_E0.8410.29
20_D131_D0.8360.28
80_E136_D0.8330.28
2_A9_R0.8230.28
74_K96_L0.8230.28
58_G64_V0.8220.28
76_T85_E0.8200.28
16_R49_Q0.8140.27
64_V68_K0.7970.27
72_G95_L0.7960.27
53_K106_V0.7950.26
66_D69_L0.7880.26
63_P131_D0.7840.26
34_E94_N0.7790.26
36_R58_G0.7770.26
2_A100_V0.7760.26
87_E106_V0.7620.25
43_Q116_K0.7600.25
29_D145_S0.7550.25
47_P76_T0.7500.24
16_R68_K0.7490.24
27_D127_R0.7450.24
17_P119_L0.7450.24
99_A126_I0.7440.24
111_Q136_D0.7420.24
39_E77_E0.7410.24
19_A137_K0.7350.24
16_R75_V0.7350.24
114_Q131_D0.7300.24
64_V96_L0.7280.23
127_R150_R0.7260.23
74_K93_R0.7230.23
36_R66_D0.7210.23
24_E39_E0.7200.23
149_A152_I0.7160.23
17_P124_S0.7150.23
141_E146_Y0.7110.23
25_W56_D0.7110.23
45_H49_Q0.7080.23
114_Q117_R0.7050.23
11_S70_A0.7040.22
3_R10_G0.7020.22
148_T153_I0.6990.22
4_M74_K0.6990.22
43_Q115_N0.6940.22
11_S78_I0.6930.22
29_D76_T0.6930.22
16_R108_A0.6920.22
91_D129_L0.6920.22
28_V58_G0.6900.22
115_N124_S0.6900.22
5_H135_G0.6860.22
21_E34_E0.6820.22
33_I153_I0.6800.22
1_M6_T0.6740.21
75_V135_G0.6690.21
103_H130_A0.6620.21
116_K149_A0.6510.20
12_S76_T0.6470.20
41_A47_P0.6360.20
83_D131_D0.6330.20
96_L152_I0.6300.20
66_D71_T0.6280.19
119_L144_Y0.6250.19
134_R143_A0.6210.19
2_A95_L0.6160.19
103_H119_L0.6150.19
31_D58_G0.6110.19
12_S82_H0.6070.19
93_R113_H0.6050.19
30_E64_V0.6030.19
7_R150_R0.6010.19
64_V73_K0.5990.18
110_G122_T0.5980.18
80_E124_S0.5980.18
11_S81_A0.5980.18
38_V65_P0.5960.18
69_L78_I0.5960.18
48_S76_T0.5930.18
124_S131_D0.5920.18
63_P146_Y0.5920.18
115_N145_S0.5910.18
79_L104_E0.5880.18
22_P137_K0.5870.18
34_E82_H0.5840.18
32_A136_D0.5840.18
2_A101_R0.5800.18
79_L85_E0.5790.18
12_S50_I0.5790.18
39_E73_K0.5780.18
55_R112_D0.5750.18
23_P55_R0.5720.17
110_G118_A0.5700.17
70_A151_E0.5700.17
78_I126_I0.5690.17
85_E88_L0.5680.17
46_D109_N0.5670.17
25_W65_P0.5630.17
75_V147_E0.5530.17
38_V126_I0.5510.17
25_W72_G0.5470.17
64_V81_A0.5460.17
4_M10_G0.5450.17
10_G17_P0.5450.17
72_G113_H0.5400.16
70_A79_L0.5380.16
42_E63_P0.5380.16
4_M7_R0.5370.16
10_G14_S0.5360.16
9_R40_L0.5330.16
45_H136_D0.5330.16
43_Q97_E0.5330.16
43_Q117_R0.5310.16
24_E143_A0.5300.16
85_E124_S0.5260.16
47_P77_E0.5200.16
69_L73_K0.5200.16
55_R65_P0.5190.16
19_A103_H0.5150.16
125_K150_R0.5120.16
12_S115_N0.5080.15
100_V149_A0.5060.15
64_V67_V0.5050.15
99_A119_L0.5000.15
34_E73_K0.5000.15
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3j7aU 1 0.9548 100 0.131 Contact Map
3zeyG 1 0.9032 100 0.132 Contact Map
4bpeO 1 0.9613 100 0.14 Contact Map
4ujpO 1 0.9613 100 0.149 Contact Map
3j20Q 1 0.9677 100 0.306 Contact Map
5aj3O 1 0.6839 98.6 0.851 Contact Map
4iylA 3 0.5032 97.7 0.881 Contact Map
4a5uB 1 0.4581 97.6 0.884 Contact Map
3bbnO 1 0.5032 97.6 0.884 Contact Map
4rb5O 1 0.5097 97.4 0.889 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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